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Aortic insufficiency

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https://www.readbyqxmd.com/read/28524247/comparison-of-adjuvant-therapy-for-node-positive-clinical-stage-ib-iib-cervical-cancer-systemic-chemotherapy-versus-pelvic-irradiation
#1
Koji Matsuo, Muneaki Shimada, Yoichi Aoki, Masaru Sakamoto, Nobuhiro Takeshima, Hisaya Fujiwara, Takashi Matsumoto, Mikio Mikami, Toru Sugiyama
This was a nation-wide retrospective study in Japan examining women who underwent radical hysterectomy for clinical stage IB-IIB cervical cancer with pelvic and/or para-aortic lymph node metastasis between 2004 and 2008. Time to recurrence or death and patterns of disease recurrence were compared based upon the adjuvant treatment pattern: whole pelvic radiotherapy alone (n=253), concurrent chemo-radiotherapy (CCRT, n=502), and chemotherapy alone (n=319). Women who received chemotherapy alone had similar recurrence (5-year rates, 36...
May 19, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28502074/causes-and-consequences-of-mesenteric-embolization-after-endovascular-aorto-iliac-intervention-a-nested-case-control-study
#2
Stefan Acosta, Jussi Kärkkäinen
BACKGROUND: Causes and consequences of mesenteric embolization after endovascular aorto-iliac procedures have not been studied adequately. METHODS: Consecutive patients with mesenteric embolization after endovascular aorto-iliac intervention between 2011 and 2015 (case-group, n = 9) were investigated and compared with age, gender and procedure-matched random controls (n = 36). RESULTS: Compared to the control group, a higher proportion of patients with mesenteric embolization were current smokers (89% vs...
May 14, 2017: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/28498897/which-technique-of-cusp-repair-is-durable-in-reimplantation-procedure-%C3%A2
#3
Hiroshi Tanaka, Hiroaki Takahashi, Takeshi Inoue, Takashi Matsueda, Tatsuya Oda, Noriyuki Abe, Yoshikatsu Nomura, Yasuko Gotake, Yutaka Okita
OBJECTIVES: We aimed to ascertain the durability of cusp repair techniques used in reimplantation procedures. METHODS: Between 2000 and 2015, 249 patients (mean age, 49 ± 17 years) with aortic insufficiency underwent the reimplantation procedure. The pathology was acute aortic dissection in 24 and non-dissection in 225 patients. Preoperative aortic regurgitation (AR) was absent in 9, 1+ in 19, 2+ in 20, 3+ in 71 and 4+ in 120 patients. The mean aortic root and ascending aortic diameters were 47 ± 9 mm and 38 ± 7 mm, respectively...
May 11, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28496512/takayasu-s-arteritis-presenting-with-headache-and-peripheral-facial-palsy-a-case-report
#4
Maryam Sotoudeh Anvari, Farzad Masoudkabir, Kyomars Abbasi, Mohammad Ali Boroumand, Manijeh Zarghampour, Hamidreza Goodarzynejad
Takayasu's arteritis (TA) is a rare case of granulomatous arteritis which mainly involves the aorta and its large branches. Although arterial hypertension is the most common feature of the disease in both adults and children, patients with TA may present with numerous clinical manifestations. Our patient was a 45-year-old woman, known to have hypertension from 3 years earlier following assessments made for severe headache. One year after the diagnosis of hypertension, she developed a left-sided lower motor neuron facial palsy, which was treated with oral corticosteroids (Prednisolone)...
October 3, 2016: Journal of Tehran Heart Center
https://www.readbyqxmd.com/read/28493342/rapid-deployment-aortic-valve-replacement-versus-standard-bioprosthesis-implantation
#5
Enrico Ferrari, Christelle Roduit, Pauline Salamin, Elena Caporali, Stefanos Demertzis, Piergiorgio Tozzi, Denis Berdajs, Ludwig von Segesser
OBJECTIVE: To compare the outcome and the 1-year hemodynamic results of the rapid-deployment Intuity valve versus the Perimount Magna bioprosthesis in matched populations. METHODS: Between March 2014 and May 2015, 32 patients underwent aortic valve replacement with the Intuity valve (Intuity-group). These patients were compared to a matched population of Perimount valves implanted during the same period of time (Perimount-group). Clinical data were compared and echocardiographic 1-year follow-up was performed...
May 11, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28492719/does-aortic-valve-repair-in-valve-sparing-aortic-root-reconstruction-compromise-the-longevity-of-the-procedure
#6
Ricardo Ribeiro Dias, José Augusto Duncan, Fabrício José de Souza Dinato, Lucas Lacerda Araújo, Hugo Monteiro Neder Issa, Fábio Fernandes, Charles Mady, Fábio Biscegli Jatene
OBJECTIVES: The effect of performing aortic valve repair in combination with valve-sparing operation on the length of time for which patients are free from reoperation is unclear. The objective of this study was to determine if the performance of aortic valve repair during valve-sparing operation modified the freedom from reoperation time. METHODS: From January 2003 to July 2014, 78 patients with a mean age of 49±15 years underwent valve-sparing operation. Sixty-eight percent of these patients were male...
April 2017: Clinics
https://www.readbyqxmd.com/read/28489254/use-of-intra-aortic-counterpulsation-in-cardiogenic-shock-post-liver-transplantation
#7
Arun P Palanisamy, Satish N Nadig, Gabriel R Chedister, Jacob E Dowden, David G Koch, William D Stoll, John W McGillicuddy, Kenneth D Chavin
Left ventricular dysfunction resulting in cardiogenic shock occurs infrequently following organ reperfusion in liver transplantation. The etiology of the cardiogenic shock is often multifactorial and difficult to manage due to the complex nature of the procedure and the patient's baseline physiology. Traditionally, this hemodynamic instability is managed medically using inotropic agents and vasopressor support. If medical treatment is insufficient, the use of an intra-aortic balloon pump for counterpulsation may be employed to improve the hemodynamics and stabilize the patient...
May 10, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28486172/synergistic-effect-of-low-k-and-d-vitamin-status-on-arterial-stiffness-in-a-general-population
#8
Otto Mayer, Jitka Seidlerová, Peter Wohlfahrt, Jan Filipovský, Renata Cífková, Václava Černá, Alena Kučerová, Martin Pešta, Radka Fuchsová, Ondřej Topolčan, Kelly M C Jardon, Nadja E A Drummen, Cees Vermeer
Both vitamins K and D are nutrients with pleiotropic functions in human tissues. The metabolic role of these vitamins overlaps considerably in calcium homeostasis. We analyzed their potential synergetic effect on arterial stiffness. In a cross-sectional study, we analyzed aortic pulse wave velocity (aPWV) in 1023 subjects from the Czech post-MONICA study. Desphospho-uncarboxylated matrix γ-carboxyglutamate protein (dp-ucMGP), a biomarker of vitamin K status, was measured by sandwich ELISA and 25-hydroxyvitamin D3 (25-OH-D3) by a commercial immunochemical assay...
April 22, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28485110/the-role-of-neo-sinus-reconstruction-in-aortic-valve-sparing-surgery
#9
Mario Gaudino, Antonino Di Franco, Luca Weltert, Umberto Benedetto, Christopher Lau, Ivancarmine Gambardella, Ruggero De Paulis, Leonard N Girardi
AIMS: The aim of this study was to evaluate the clinical and echocardiographic results and the predictors of outcomes in patients undergoing valve-sparing operation (VSO) at two aortic centers. In addition, we sought to evaluate the potential effect of recreation of the sinuses of Valsalva (SV) on the outcome of valve-sparing procedures. METHODS: During a 14-year period, 328 patients underwent aortic valve-sparing root replacement at two institutions. Clinical and echo evaluation was performed 6 months after surgery and every year thereafter or in case of clinical symptoms...
May 8, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28475802/complete-fusion-of-a-percutaneous-aortic-valve-placed-after-ventricular-assist-device
#10
Stephen L Derryberry, Renaldo D Williams, Joseph L Fredi, Stephen K Ball
Severe aortic insufficiency following continuous flow left ventricular assist device (LVAD) placement requires intervention. Conventional corrective approaches are varied and morbid. Increasingly, percutaneous solutions, such as transcatheter aortic valve replacement (TAVR), have been used to rescue these patients. The unique flow characteristics in the aortic root following LVAD implantation may have unintended consequences to the TAVR leaflets. We describe the premature fusion of TAVR leaflets following 159 days of LVAD support...
May 4, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28473362/helcococcus-kunzii-prosthetic-valve-endocarditis-secondary-to-lower-extremity-cellulitis
#11
Saira Farid, William Miranda, Joseph Maleszewski, Muhammad Rizwan Sohail
An 88-year-old man with history of bioprosthetic aortic valve replacement was hospitalised with fever, chills, malaise and right lower extremity cellulitis. Laboratory investigations revealed leucocytosis and blood cultures grew Helcococcus kunzii Although transoesophageal echocardiography was negative for endocarditis, the patient was treated with 4 week of intravenous ceftriaxone. However, he was readmitted 6 weeks later with symptoms of fever, chills and hypoxia in setting of recurrent H. kunzii bacteraemia...
May 3, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28471523/laparoscopic-surgery-for-elective-abdominal-aortic-aneurysm-repair
#12
REVIEW
Lindsay Robertson, Sandip Nandhra
BACKGROUND: Abdominal aortic aneurysm (AAA) is an abnormal dilatation of the infradiaphragmatic aorta that is equal to or greater than 30 mm or a local dilatation of equal to or greater than 50% compared to the expected normal diameter of the artery. AAAs rarely occur in individuals under 50 years of age, but thereafter the prevalence dramatically increases with age, with men at a six-fold greater risk of developing an AAA than women. Prevalence of AAA has been reported to range from 1...
May 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28461798/transcatheter-aortic-valve-implantation-in-a-patient-with-unicuspid-aortic-valve
#13
Angelo Nascimbene, Pranav Loyalka, Igor D Gregoric, Ricardo Bellera, Maan Malahfji, Marija Petrovic, Biswajit Kar
Transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic valves has been successfully performed, but there is a lack of published experience in percutaneous treatment of patients with unicuspid valves and severe aortic stenosis. We describe a case of TAVR in such a patient. A 31-year-old woman with Turner syndrome-who had undergone coarctation repair via subclavian flap at age 7 days and an aortic valvotomy at age 6 weeks-presented with severe symptomatic aortic stenosis. She was deemed inoperable because of her severe pulmonary hypertension and numerous comorbidities; consequently, a 20-mm Edwards Sapien 3 Transcatheter Heart Valve was offered for compassionate use...
April 2017: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/28453792/triple-valve-surgery-through-a-less-invasive-approach-early-and-mid-term-results
#14
Petar Risteski, Nadejda Monsefi, Aleksandra Miskovic, Tanja Josic, Sherife Bala, Razan Salem, Andreas Zierer, Anton Moritz
OBJECTIVES: A partial upper sternotomy has become established as a less invasive approach mainly for single and double valve surgery. This report evaluates the clinical outcomes of triple valve surgery performed through a partial upper sternotomy. METHODS: We reviewed the medical records of 37 consecutive patients (28 men, 76%) who underwent triple valve surgery through a partial upper sternotomy between 2005 and 2015. The patients' mean age was 67 ± 17 years; 27 (73%) were in New York Heart Association Class III or IV...
May 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28443262/a-rare-association-of-central-hypothyroidism-and-adrenal-insufficiency-in-a-boy-with-williams-beuren-syndrome
#15
Devi Dayal, Dinesh Giri, Senthil Senniappan
Primary hypothyroidism related to morphological and volumetric abnormalities of the thyroid gland is one of the commonest of several endocrine dysfunctions in Williams-Beuren syndrome (WBS). We report a 10-month-old boy with WBS who presented with central hypothyroidism. During the neonatal period, he had prolonged jaundice, feeding difficulties and episodes of colic that continued during early infancy. Additionally, there was slowing of growth and mild developmental delay. He underwent surgical repair for supravalvular aortic stenosis at 6 months of age...
March 2017: Annals of Pediatric Endocrinology & Metabolism
https://www.readbyqxmd.com/read/28442330/symptomatic-carotid-artery-disease-revascularization
#16
REVIEW
Piero Montorsi, Stefano Galli, Paolo M Ravagnani, Marco Roffi
Patients with symptomatic carotid artery disease should be managed by a multidisciplinary team including neurologists, vascular surgeons and interventionalists. Duplex ultrasound is the most widely used diagnostic modality to assess carotid disease, followed by additional imaging tests (CT- or MR-angiography) to confirm the severity of the stenosis, detect brain lesions, and assess intracranial circulation as well as the supra-aortic anatomy. Although overall randomized trial results favored (CEA) over carotid artery stenting (CAS) in symptomatic patients, this was likely related to the insufficient expertise of the endovascular specialists in several of the trials...
April 22, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28435003/the-hemodynamic-effects-of-aortic-insufficiency-in-patients-supported-with-continuous-flow-left-ventricular-assist-devices
#17
Gabriel Sayer, Nitasha Sarswat, Gene H Kim, Sirtaz Adatya, Diego Medvedofsky, Daniel Rodgers, Eric Kruse, Takeyoshi Ota, Valluvan Jeevanandam, Roberto Lang, Nir Uriel
BACKGROUND: The impact of aortic insufficiency (AI) on the morbidity and mortality of left ventricular assist device (LVAD) patients remains controversial. This study's aim was to assess the hemodynamics of LVAD patients with at least mild AI, at baseline and in response to device speed changes. METHODS AND RESULTS: Asymptomatic LVAD patients were prospectively enrolled and underwent a hemodynamic and echocardiographic ramp study. Hemodynamics at rest and in response to device speed changes were compared between patients with at least mild AI at their baseline speed and patients without AI...
April 20, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/28435002/systemic-arterial-hypertension-secondary-to-chronic-kidney-disease-in-two-captive-born-large-felids
#18
A Leclerc, E Trehiou-Sechi, E M Greunz, C Damoiseaux, J Bouvard, V Chetboul
Systemic arterial hypertension (SHT) has been widely described in the domestic cat (Felis catus). In these feline patients, SHT is considered as the most common vascular disorder of middle-aged to older animals, and secondary SHT related to chronic kidney disease (CKD) represents the most common form of the disease. We describe here the first two cases of spontaneous SHT in large felids, i.e. one 18-year old, 34.4 kg, male North-Chinese leopard (Panthera pardus japonensis, case #1) and one 20-year old, 28...
April 20, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28433490/evaluating-health-of-emerging-economies-through-the-eyes-of-heart-valve-disease-in%C3%A2-the%C3%A2-transcatheter-era
#19
REVIEW
Sameer Arora, Cassandra J Ramm, Amol A Bahekar, John P Vavalle
China and India are the 2 fastest growing major world economies. However, they suffer from great differences in health policies, demographics, and rates of population growth. Whereas China has seen a steep decline in rheumatic heart disease (RHD) and a rise in life expectancy, India continues to suffer from a significant burden of RHD due to insufficient distribution of economic prosperity to health care, denser population, and ineffective application of World Health Organization RHD prevention guidelines. As China faces the burden of the world's largest geriatric population, focus has shifted to calcific aortic stenosis for which it prepares by expansions in the field of transcatheter aortic valve replacement...
April 19, 2017: Global Heart
https://www.readbyqxmd.com/read/28433350/open-repair-of-chronic-thoracic-and-thoracoabdominal-aortic-dissection-using-deep-hypothermia-and-circulatory-arrest
#20
Joel Corvera, Hannah Copeland, David Blitzer, Adam Hicks, Joshua Manghelli, Philip Hess, John Fehrenbacher
BACKGROUND: Chronic dissection of the thoracic and thoracoabdominal aorta as sequela of a prior type A or B dissection is a challenging problem that requires close radiographic surveillance and prompt operative intervention in the presence of symptoms or aneurysm formation. Open repair of chronic thoracic and thoracoabdominal aortic dissection using deep hypothermia has been our preferred method to treat this complex pathology. The advantages of this technique include organ and spinal cord protection, the flexibility to extend the repair proximally into the arch, and the ability to limit ischemia to all vascular beds...
March 18, 2017: Journal of Thoracic and Cardiovascular Surgery
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