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https://www.readbyqxmd.com/read/28202707/cadasil-accelerated-by-acute-hypotension-arterial-and-venous-contribution-to-leukoaraiosis
#1
Jacqueline A Pettersen, Julia Keith, Fuqiang Gao, J David Spence, Sandra E Black
OBJECTIVE: To underline the importance of blood pressure regulation in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and to describe changes that occur in the veins in this condition, specifically venous collagenosis associated with leukoaraiosis. METHODS: Case report with neuroimaging and pathologic data. RESULTS: A 61-year-old man with genetically confirmed CADASIL was initially lucid following a motor vehicle accident but subsequently became hypotensive (60/40 mm Hg) due to an open femur fracture and required intubation...
February 15, 2017: Neurology
https://www.readbyqxmd.com/read/28153949/factors-associated-with-left-atrial-remodeling-in-the-general-population
#2
Walter Oliver, Gwendolyn Matthews, Colby R Ayers, Sonia Garg, Sachin Gupta, Ian J Neeland, Mark H Drazner, Jarett D Berry, Susan Matulevicius, James A de Lemos
BACKGROUND: Although contributors to remodeling of the left ventricle (LV) have been well studied in general population cohorts, few data are available describing factors influencing changes in left atrial (LA) structure. METHODS AND RESULTS: Maximum LA volume was determined by cardiac magnetic resonance imaging among 748 participants in the Dallas Heart Study at 2 visits a mean of 8 years apart. Associations of changes in LA volume (ΔLAV) with traditional risk factors, biomarkers, LV geometry, and remodeling by cardiac magnetic resonance imaging and detailed measurements of global and regional adiposity (by magnetic resonance imaging and dual-energy x ray absorptiometry) were assessed using multivariable linear regression...
February 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28138817/incremental-value-of-cardiac-magnetic-resonance-for-the-evaluation-of-cardiac-tumors-in-adults-experience-of-a-high-volume-tertiary-cardiology-centre
#3
Sorin Giusca, Derliz Mereles, Andreas Ochs, Sebastian Buss, Florian André, Sebastian Seitz, Johannes Riffel, Philipp Fortner, Mindaugas Andrulis, Stefan Schönland, Hugo A Katus, Grigorios Korosoglou
To assess the value of cardiac magnetic resonance imaging (CMR) in evaluating cardiac tumours in a tertiary cardiology centre. Between 2004 and 2014, 125 patients (pts.) from a total of 17000 who received a CMR examination in our institution were referred with the suspicion of cardiac tumours. A dedicated protocol was used that included standard cine SSFP acquisitions as well as tissue characterization using T1 and T2 black-blood (T1 BB and T2 BB respectively) with and without fat suppression, perfusion of the structure and late gadolinium enhancement...
January 30, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28123058/procalcitonin-and-midregional-proatrial-natriuretic-peptide-as-biomarkers-of-subclinical-cerebrovascular-damage-the-northern-manhattan-study
#4
Mira Katan, Yeseon Moon, Arnold von Eckardstein, Kathartina Spanaus, Janet DeRosa, Jose Gutierrez, Charles DeCarli, Clinton Wright, Ralph Sacco, Mitchell Elkind
BACKGROUND AND PURPOSE: Chronic infections and cardiac dysfunction are risk factors for stroke. We hypothesized that blood biomarkers of infection (procalcitonin) and cardiac dysfunction (midregional proatrial natriuretic peptide [MR-proANP]), previously associated with small vessel stroke and cardioembolic stroke are also associated with subclinical cerebrovascular damage, including silent brain infarcts and white matter hyperintensity volume. METHODS: The NOMAS (Northern Manhattan Study) was designed to assess risk factors for incident vascular disease in a multiethnic cohort...
January 25, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28122903/ischemic-lesions-blood-pressure-dysregulation-and-poor-outcomes-in-intracerebral-hemorrhage
#5
Chelsea S Kidwell, Jonathan Rosand, Gina Norato, Simone Dixon, Bradford B Worrall, Michael L James, Mitchell S V Elkind, Matthew L Flaherty, Jennifer Osborne, Anastasia Vashkevich, Carl D Langefeld, Charles J Moomaw, Daniel Woo
OBJECTIVE: To evaluate the associations among diffusion-weighted imaging (DWI) lesions, blood pressure (BP) dysregulation, MRI markers of small vessel disease, and poor outcome in a large, prospective study of primary intracerebral hemorrhage (ICH). METHODS: The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study is a multicenter, observational study of ICH among white, black, and Hispanic patients. RESULTS: Of 600 patients, mean (±SD) age was 60...
January 25, 2017: Neurology
https://www.readbyqxmd.com/read/28109887/compressed-sensing-based-simultaneous-black-and-gray-blood-carotid-vessel-wall-mr-imaging
#6
Bo Li, Hao Li, Hanjing Kong, Li Dong, Jue Zhang, Jing Fang
OBJECTIVE: In this study, we sought to demonstrate the blood suppression performance, image quality and morphological measurements for compressed sensing (CS) based simultaneous 3D black- and gray-blood imaging sequence (CS-siBLAG) in carotid vessel wall MR imaging. MATERIALS AND METHODS: Seven healthy volunteers and five patients were recruited. Healthy subjects underwent five CS-siBLAG scans with 1, 2, 3, 4 and 5-fold accelerations. Signal-to-tissue ratio (STR) and contrast-to-tissue ratio (CTR) were computed as the measures of flowing signal suppression performance and the image quality for black-blood imaging of the technique...
January 19, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28100004/technical-note-measurement-of-common-carotid-artery-lumen-dynamics-using-black-blood-mr-cine-imaging
#7
Erpeng Dai, Li Dong, Zhe Zhang, Lyu Li, Hui Zhang, Xihai Zhao, Jinnan Wang, Chun Yuan, Hua Guo
PURPOSE: To demonstrate the feasibility of measuring the common carotid artery (CCA) lumen dynamics using a black blood cine (BB-cine) imaging method. METHODS: Motion-sensitized driven-equilibrium (MSDE) prepared spoiled gradient sequence was used for the BB-cine imaging. CCAs of eleven healthy volunteers were studied using this method. Lumen dynamics, including lumen area evolution waveforms and distension values, were measured and evaluated by comparing this method with bright blood cine (BrB-cine) imaging...
January 18, 2017: Medical Physics
https://www.readbyqxmd.com/read/28095878/black-blood-thrombus-imaging-bti-a-contrast-free-cardiovascular-magnetic-resonance-approach-for-the-diagnosis-of-non-acute-deep-vein-thrombosis
#8
Guoxi Xie, Hanwei Chen, Xueping He, Jianke Liang, Wei Deng, Zhuonan He, Yufeng Ye, Qi Yang, Xiaoming Bi, Xin Liu, Debiao Li, Zhaoyang Fan
BACKGROUND: Deep vein thrombosis (DVT) is a common but elusive illness that can result in long-term disability or death. Accurate detection of thrombosis and assessment of its size and distribution are critical for treatment decision-making. In the present study, we sought to develop and evaluate a cardiovascular magnetic resonance (CMR) black-blood thrombus imaging (BTI) technique, based on delay alternating with nutation for tailored excitation black-blood preparation and variable flip angle turbo-spin-echo readout, for the diagnosis of non-acute DVT...
January 18, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28092315/choroidal-blood-vessels-in-retinal-pigment-epithelial-atrophy-using-optical-coherence-tomography-angiography
#9
Ichiro Maruko, Hideki Koizumi, Shota Sawaguchi, Taiji Hasegawa, Hisaya Arakawa, Tomohiro Iida
PURPOSE: To observe choroidal blood vessels in cases sharply demarcated with retinal pigment epithelium (RPE) atrophy at the macular area using en-face optical coherence tomography angiography (OCTA) and standard en-face optical coherence tomography (OCT). METHODS: The retrospective study included 12 eyes (8 patients; 5 men, 3 women; average age, 64.3 years) with RPE atrophy seen by ophthalmoscopy. The macular areas with normal and atrophic RPE sections were examined using en-face OCTA with an 840-nm light source (RTVue XR Avanti; Optovue Inc), which system can obtain standard en-face OCT images at identical areas...
January 13, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28034564/acute-black-tea-consumption-improves-cutaneous-vascular-function-in-healthy-middle-aged-humans
#10
Kirsty A Woodward, Nicola D Hopkins, Richard Draijer, Young de Graaf, David A Low, Dick H J Thijssen
BACKGROUND & AIMS: Dietary flavonoids, such as those present in black tea, are associated with reduced risk of cardiovascular disease (CVD), possibly through improving nitric oxide (NO) mediated vascular function. The aim of this study was to examine the effect of acute black tea ingestion on cutaneous microvascular function. METHODS: Twenty healthy participants (58 ± 5 y, 9 men) attended two experimental trials (tea, placebo), 7-days apart in a randomised, controlled, double-blind, cross-over design...
December 22, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28027739/intracranial-arterial-wall-enhancement-using-gadolinium-enhanced-3d-black-blood-t1-weighted-imaging
#11
Koichi Takano, Kosuke Hida, Yasuo Kuwabara, Kengo Yoshimitsu
PURPOSE: We investigated the enhancement of the intracranial arterial walls with gadolinium-enhanced, black-blood three-dimensional T1-weighted imaging (Gd-3DBB) by using an improved motion-sensitized driven-equilibrium (iMSDE)-prepared volumetric isotropic turbo spin-echo acquisition (VISTA). METHODS: A total of 115 patients underwent FLAIR, 3D-TOF-MRA and Gd-3DBB with a 1.5-T scanner. The degree and distribution of the arterial wall enhancement on Gd-3DBB was assessed...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/27888153/three-dimensional-black-blood-t2-mapping-with-compressed-sensing-and-data-driven-parallel-imaging-in-the-carotid-artery
#12
Jianmin Yuan, Ammara Usman, Scott A Reid, Kevin F King, Andrew J Patterson, Jonathan H Gillard, Martin J Graves
PURPOSE: To develop a 3D black-blood T2 mapping sequence with a combination of compressed sensing (CS) and parallel imaging (PI) for carotid wall imaging. MATERIALS AND METHODS: A 3D black-blood fast-spin-echo (FSE) sequence for T2 mapping with CS and PI was developed and validated. Phantom experiments were performed to assess T2 accuracy using a Eurospin Test Object, with different combination of CS and PI acceleration factors. A 2D multi-echo FSE sequence was used as a reference to evaluate the accuracy...
November 22, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27867171/optimal-imaging-parameters-and-the-advantage-of-renal-artery-image-using-time-spatial-labeling-inversion-pulse-at-3-tesla-magnetic-resonance-imaging-comparison-of-image-quality-for-1-5-tesla-magnetic-resonance-imaging
#13
Keita Fukushima, Isao Miyazaki, Kuninori Kobayashi, Makio Ooto
With the recent spread of three tesla (3 T) magnetic resonance imaging (MRI), time-spatial labeling inversion pulse (Time-SLIP) technique at high magnetic field can be used. The purpose of this study was to determine appropriate renal artery imaging parameters and to compare with the 1.5 T MRI image quality of a renal artery using the Time-SLIP technique. The imaging sequence was 3D true steady-state free precession (True SSFP), and using respiratory gated by the voice instructions of breath interval 2, 4, 6 seconds...
2016: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/27866381/cardiac-magnetic-resonance-imaging-of-patent-ductus-arteriosus-in-three-dogs
#14
Youngjae Lee, Jaihyun Jung, Junyong Park, Jiyoon Jeong, Seokho Jeon, Sunyoung Park, Jinhwa Chang, Ji-Houn Kang, Chulhyun Lee, Dongwoo Chang
Patent ductus arteriosus (PDA) is the most common congenital cardiovascular disorder in dogs and requires an accurate diagnosis for an appropriate treatment. Cardiac MRI (cMRI) has been reported as a method for characterization of canine thoracic vasculature. However, to the authors' knowledge, no published studies describe evaluation of canine PDA through cMRI. Three dogs were selected for this exploratory study. Electrocardiogram gating and breath-hold techniques were performed using a 3T MR scanner. Both black blood imaging and bright blood cine acquisitions were performed...
January 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/27856437/quantifying-intracranial-plaque-permeability-with-dynamic-contrast-enhanced-mri-a-pilot-study
#15
P Vakil, A H Elmokadem, F H Syed, C G Cantrell, F H Dehkordi, T J Carroll, S A Ansari
BACKGROUND AND PURPOSE: Intracranial atherosclerotic disease plaque hyperintensity and/or gadolinium contrast enhancement have been studied as imaging biomarkers of acutely symptomatic ischemic presentations using single static MR imaging measurements. However, the value in modeling the dynamics of intracranial plaque permeability has yet to be evaluated. The purpose of this study was to use dynamic contrast-enhanced MR imaging to quantify the contrast permeability of intracranial atherosclerotic disease plaques in symptomatic patients and to compare these parameters against existing markers of plaque volatility using black-blood MR imaging pulse sequences...
February 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27826082/spectrally-presaturated-modulation-spm-an-efficient-fat-suppression-technique-for-steam-based-cardiac-imaging-sequences
#16
Ahmed S Fahmy, El-Sayed H Ibrahim, Nael F Osman
Stimulated-echo acquisition mode (STEAM) is a key pulse sequences in MRI in general, and in cardiac imaging in particular. Fat suppression is an important feature in cardiac imaging to improve visualization and eliminate off-resonance and chemical-shift artifacts. Nevertheless, fat suppression comes at the expense of reduced temporal resolution and signal-to-noise ratio (SNR). The purpose of this study is to develop an efficient fat suppression method (Spectrally-Presaturated Modulation) for STEAM-based sequences to enable imaging with high temporal-resolution, high SNR, and no increase in scan time...
November 5, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27775841/evaluation-of-an-fmri-uspio-based-assay-in-healthy-human-volunteers
#17
Richard Baumgartner, William Cho, Alexandre Coimbra, Christopher Chen, Zaiqi Wang, Arie Struyk, Narayanaswamy Venketasubramanian, May Low, Cindy Gargano, Fuqiang Zhao, Donald Williams, Torsten Reese, Stephanie Seah, Dai Feng, Sonya Apreleva, Esben Petersen, Jeffrey L Evelhoch
PURPOSE: To present the testretest and contrast dose effect results of cerebral blood volume (CBV) functional MRI (fMRI) in healthy human volunteers using ferumoxytol (Feraheme), an ultrasmall-superparamagnetic iron oxide (USPIO) nanoparticle. MATERIALS AND METHODS: This was an open-label, two-period, fixed-sequence study in healthy young volunteers. In eight subjects, using a 3 Tesla field strength system, blood oxygen level dependent (BOLD) and CBV fMRI were acquired in response to a visual black-and-white checkboard stimulation paradigm using an escalating ferumoxytol dose design (250, 350, and 510 mg iron)...
October 24, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27765555/magnetic-resonance-imaging-based-assessment-of-carotid-atheroma-a-comparative-study-of-patients-with-and-without-coronary-artery-disease
#18
Ammara Usman, Umar Sadat, Zhongzhao Teng, Martin J Graves, Jonathan R Boyle, Kevin Varty, Paul D Hayes, Jonathan H Gillard
BACKGROUND: Functional magnetic resonance (MR) imaging of atheroma using contrast media enables assessment of the systemic severity of atherosclerosis in different arterial beds. Whether black-blood imaging has similar ability remains widely unexplored. In this study, we evaluate whether black-blood imaging can differentiate carotid plaques of patients with and without coronary artery disease (CAD) in terms of morphological and biomechanical features of plaque vulnerability, thereby allowing assessment of the systemic severity nature of atherosclerosis in different arterial beds...
October 17, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27761546/a-significant-enhancement-of-color-transition-from-an-on-off-type-achromatic-colorimetric-nanosensor-for-highly-sensitive-multi-analyte-detection-with-the-naked-eye
#19
Jun Hyuk Heo, Gyu Sung Yi, Byoung Sang Lee, Hui Hun Cho, Jin Woong Lee, Jung Heon Lee
Here, we report the development of an achromatic nanoparticle-based colorimetric sensor (achromatic nanosensor) with an on-off type color change that significantly enhances the color transition and increases the sensitivity of the sensor for naked-eye inspection. The achromatic nanosensor was prepared via a modified CMYK (CRYK) subtractive color model by combining DNA-functionalized gold nanoparticles (AuNPs-DNA), silver nanoparticles (AgNPs-DNA), and gold nanorods (AuNRs-DNA). The initially black-colored achromatic nanosensor not only allowed multiplexed detection by generating target-specific diverse color changes, but also improved the recognition of color changes by the naked eye...
October 20, 2016: Nanoscale
https://www.readbyqxmd.com/read/27754031/yia-03-07-reactive-oxygen-species-adversely-relates-to-early-vascular-changes-and-arterial-stiffness-in-black-normotensive-smokers-the-african-predict-study
#20
Ruan Kruger, Moliehi Mothae, Wayne Smith
OBJECTIVE: Cigarette smoking weakens the antioxidant defence system and is considered a lifestyle risk factor contributing to cardiovascular disease progression. Little information exists on these links in non-smoking versus smoking populations. We aimed to explore the associations of oxidative stress with markers of vascular function in a young, normotensive bi-ethnic population. DESIGN AND METHOD: We included 237 non-smokers (108 black and 129 white) and 145 smokers (78 black and 67 white) from South Africa between ages 20 and 30 years...
September 2016: Journal of Hypertension
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