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https://www.readbyqxmd.com/read/29775945/greenhouse-gas-emissions-reduction-in-different-economic-sectors-mitigation-measures-health-co-benefits-knowledge-gaps-and-policy-implications
#1
REVIEW
Jinghong Gao, Hongli Hou, Yunkai Zhai, Alistair Woodward, Sotiris Vardoulakis, Sari Kovats, Paul Wilkinson, Liping Li, Xiaoqin Song, Lei Xu, Bohan Meng, Xiaobo Liu, Jun Wang, Jie Zhao, Qiyong Liu
To date, greenhouse gas (GHG) emissions, mitigation strategies and the accompanying health co-benefits in different economic sectors have not been fully investigated. The purpose of this paper is to review comprehensively the evidence on GHG mitigation measures and the related health co-benefits, identify knowledge gaps, and provide recommendations to promote further development and implementation of climate change response policies. Evidence on GHG emissions, abatement measures and related health co-benefits has been observed at regional, national and global levels, involving both low- and high-income societies...
May 15, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29775542/exercise-and-circulating-bdnf-mechanisms-of-release-and-implications-for-the-design-of-exercise-interventions
#2
Jeremy James Walsh, Michael E Tschakovsky
Engagement in regular bouts of exercise confers numerous positive effects on brain health across the lifespan. Acute bouts of exercise transiently improve cognitive function, while long-term exercise training stimulates brain plasticity, improves brain function, and helps to stave off neurological disease. The action of brain-derived neurotrophic factor (BDNF) is a candidate mechanism underlying these exercise-induced benefits and is the subject of considerable attention in the exercise-brain health literature...
May 18, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29775496/young-adult-s-knowledge-and-attitudes-towards-cardiovascular-disease-a-systematic-review-and-meta-analysis
#3
REVIEW
Ronald Trejo, Wendy Cross, John Stephenson, Karen-Leigh Edward
AIMS AND OBJECTIVES: To explore young adult's knowledge and attitudes of cardiovascular disease and its risk factors. BACKGROUND: Cardiovascular disease morbidity is rising and mortality is declining among young adults. However, the knowledge of cardiovascular disease by young adults is not well known. DESIGN: A systematic review with meta-analysis was used. METHODS: The databases of CINHAL, Medline Complete, PsychINFO and Psycharticles were searched for all studies published before June 2016...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29774927/-interpretation-on-chinese-surgeons-consensus-opinion-for-the-definition-of-gastric-stump-cancer-version-2018
#4
Zhidong Gao, Kewei Jiang, Yingjiang Ye, Shan Wang
Gastric stump cancer(GSC) is defined as newly developed remnant stomach cancer following gastrectomy. This definition initially referred to carcinoma detected in the remnant stomach more than 5 years after the primary surgery for a benign disease. Subsequently, this timeframe was extended to 10 years after the primary surgery for a malignant disease. Recently, the concept of "carcinoma in the remnant stomach(CRS)" proposed by the Japanese Gastric Cancer Association was introduced in China. The new definition encompasses all carcinomas arising in the remnant stomach following gastrectomy, irrespective of the histology of the primary lesion, extent of resection, or reconstruction method...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29774765/-staying-safe-a-narrative-review-of-falls-prevention-in-people-with-parkinson-s-pdsafe
#5
Sophia Hulbert, Lynn Rochester, Alice Nieuwboer, Vicki Goodwin, Carolyn Fitton, Kim Chivers-Seymour, Ann Ashburn
BACKGROUND: Parkinson's disease demonstrates a spectrum of motor and non-motor symptoms. Falling is common and disabling. Current medical management shows minimal impact to reduce falls or fall-related risk factors, such as deficits in gait, strength, and postural instability. Despite evidence supporting rehabilitation in reducing fall risk factors, the most appropriate intervention to reduce overall fall rate remains inconclusive. This article aims to 1) synthesise current evidence and conceptual models of falls rehabilitation in Parkinson's in a narrative review; and based on this evidence, 2) introduce the treatment protocol used in the falls prevention and multi-centre clinical trial "PDSAFE"...
May 18, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29774207/overview-of-social-cognitive-dysfunctions-in-rare-developmental-syndromes-with-psychiatric-phenotype
#6
REVIEW
Aurore Morel, Elodie Peyroux, Arnaud Leleu, Emilie Favre, Nicolas Franck, Caroline Demily
Rare neurodevelopmental syndromes often present social cognitive deficits that may underlie difficulties in social interactions and increase the risk of psychosis or autism spectrum disorders. However, little is known regarding the specificities of social cognitive impairment across syndromes while it remains a major challenge for the care. Our review provides an overview of social cognitive dysfunctions in rare diseases associated with psychiatric symptoms (with a prevalence estimated between 1 in 1,200 and 1 in 25,000 live births: 22q11...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29774131/methylation-of-dna-and-chromatin-as-a-mechanism-of-oncogenesis-and-therapeutic-target-in-neuroblastoma
#7
REVIEW
Ram Mohan Ram Kumar, Nina Felice Schor
Neuroblastoma (NB), a developmental cancer, is often fatal, emphasizing the need to understand its pathogenesis and identify new therapeutic targets. The heterogeneous pathological and clinical phenotype of NB underscores the cryptic biological and genetic features of this tumor that result in outcomes ranging from rapid progression to spontaneous regression. Despite recent genome-wide mutation analyses, most primary NBs do not harbor driver mutations, implicating epigenetically-mediated gene regulatory mechanisms in the initiation and maintenance of NB...
April 24, 2018: Oncotarget
https://www.readbyqxmd.com/read/29774010/efficacy-of-vandetanib-in-treating-locally-advanced-or-metastatic-medullary-thyroid-carcinoma-according-to-recist-criteria-a-systematic-review-and-meta-analysis
#8
Pierpaolo Trimboli, Marco Castellana, Camilla Virili, Francesco Giorgino, Luca Giovanella
Background: Vandetanib is the most largely used tyrosine kinase inhibitor (TKI) in patients with locally advanced and/or metastatic medullary thyroid cancer (MTC). Here, we conducted a systematic review on its efficacy and attempted to perform a meta-analysis adopting standardized RECIST criteria as end-points. Methods: The terms "medullary thyroid" and "protein kinase inhibitor" (then including all TKIs) were searched in PubMed, ClinicalTrials...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29773704/effect-of-dietary-omega-3-fatty-acid-supplementation-on-frailty-related-phenotypes-in-older-adults-a-systematic-review-and-meta-analysis-protocol
#9
Joanne Stocks, Ana M Valdes
INTRODUCTION: The beneficial effect of dietary omega-3 supplementation in younger adults or older people with acute or chronic disease is established. Knowledge is now needed about the effect in medically stable older people. The objective of this study is to examine and assess the evidence for a role of dietary omega-3 polyunsaturated fatty acid (PUFA) supplementation in older adults on (1) muscle mass and muscle strength, (2) inflammatory biomarkers and (3) physical activity. METHODS AND ANALYSIS: A systematic review and data synthesis will be conducted of randomised controlled trials in older people not recruited for any given disease diagnosis...
May 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29773338/taking-stock-a-systematic-review-of-archaeological-evidence-of-cancers-in-human-and-early-hominin-remains
#10
Kathryn J Hunt, Charlotte Roberts, Casey Kirkpatrick
This study summarizes data from 154 paleopathological studies documenting 272 archaeologically recovered individuals exhibiting skeletal or soft tissue evidence of cancer (malignant neoplastic disease) between 1.8 million years ago and 1900 CE. The paper reviews and summarizes the temporal, spatial and demographic distribution of the evidence and the methods used to provide the cancer diagnoses. Metastasis to bone is the most widely reported evidence (n = 161), followed by multiple myeloma (n = 55)...
May 14, 2018: International Journal of Paleopathology
https://www.readbyqxmd.com/read/29773244/are-anxiety-disorders-publications-continuing-on-a-trajectory-of-growth-a-look-at-boschen-s-2008-predictions-and-beyond
#11
Gordon J G Asmundson, Aleiia J N Asmundson
The relative health of a field of research can be approximated by assessing peer-reviewed journal publication trends for articles pertinent to that field. The most recent comprehensive assessment of publication trends in the anxiety disorders indicated that the field was on a continuing trajectory of growth (Boschen, 2008). We conducted an updated search of Medline for publications on each of the anxiety disorders from 2006 to 2016. Results indicated that there was continuing growth in anxiety disorders research overall and, particularly, for posttraumatic stress disorder, social anxiety disorder, generalized anxiety disorder, and obsessive compulsive disorder...
May 14, 2018: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29773057/nucleophagy-plays-a-major-role-in-human-diseases
#12
Nian Fu, XueFeng Yang, Linxi Chen
Nucleophagy is a selective autophagy, which selectively remove damaged or non-essential nuclear material from a cell by the autophagy pathway. Additionally, nucleophagy is crucial for promoting cell longevity and ensure body proper function. Increasing evidences have shown that nucleophagy may play a major role in such human diseases as degenerative disorders, tumorigenesis, malnutrition and metabolic disorders, parakeratosis and psoriasis. Studies indicated that nucleophagy can improve degenerative disorders by delaying premature cell senescence, prevent malnutrition and metabolic disorder via maintaining nuclear structure and releasing nutrients for energy production, and alleviate parakeratosis and psoriasis...
May 17, 2018: Current Drug Targets
https://www.readbyqxmd.com/read/29773050/the-importance-of-complying-with-vaccination-protocols-in-developed-countries-anti-vax-hysteria-and-the-spread-of-severe-preventable-diseases
#13
Franco Pandolfi, Laura Franza, Laura Todi, Valentina Carusi, Michele Centrone, Alessandro Bonomo, Estelle E Newton, Domenico Schiavino, Eleonora Nucera
BACKGROUND: Vaccines are very effective medical tools for disease prevention and life span increase. Controversies have raised concern about their safety, from autism to polio vaccine contamination with simian virus 40 (SV-40). Hysteria surrounding vaccine-associated risks has resulted in a declining number of vaccinations in developed countries. Outbreaks of vaccine-preventable diseases (e.g. measles) have occurred in Europe and North America, causing also some causalities. OBJECTIVES: In this review, data on safety and efficacy of vaccines are discussed, showing that the benefits of vaccines far outweigh the risks and that it is important to comply with vaccination protocols, to avoid spreading of severe, preventable diseases...
May 17, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29773017/gastroesophageal-reflux-disease-a-review-of-symptomatic-management
#14
Elsa S Tabrez, Azhar Hussain, Seetharama Rao, Ashraya Jagadeesh, Jagannadha Rao Peela, Shams S M Tabrez
Considered as a chronic illness, gastroesophageal reflux disease (GERD) has manifested itself as a widespread condition throughout the adult population. As a growing epidemic, GERD has reached a staggering prevalence of 10% to 20% in the Western world, by affecting up to 30 million people in the United States alone. Sixty percent of individuals in an adult population will experience symptoms and the impact of GERD over a period of 12 months, whereas a remarkable 20% to 30% of individuals will have weekly symptoms...
2018: Critical Reviews in Eukaryotic Gene Expression
https://www.readbyqxmd.com/read/29772939/enabling-appropriate-personnel-skill-mix-for-progressive-realization-of-equitable-access-to-assistive-technology
#15
Emma M Smith, Rosemary Joan Gowran, Hasheem Mannan, Brian Donnelly, Liliana Alvarez, Diane Bell, Silvana Contepomi, Liezel Ennion Wegner, Evert-Jan Hoogerwerf, Tracey Howe, Yih-Kuen Jan, Jeanne Kagwiza, Natasha Layton, Ritchard Ledgerd, Malcolm MacLachlan, Giulia Oggero, Cecilia Pettersson, Thais Pousada, Elsje Scheffler, Sam Wu
BACKGROUND AND METHODS: This paper reviews the current capacity of personnel in enabling access to assistive technology (AT) as well as the systems and processes within which they work, and was reviewed, discussed, and refined during and following the Global Research, Innovation, and Education in Assistive Technology (GREAT) Summit. FINDINGS: Key concepts addressed include a person-centred team approach; sustainability indicators to monitor, measure, and respond to needs for service design and delivery; education, research, and training for competent practice, using the six rehab-workforce challenges framework; and credentialing frameworks...
May 17, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29772869/-progression-on-finite-element-modeling-method-in-scoliosis
#16
REVIEW
Ning Fan, Lei Zang, Yong Hai, Peng Du, Shuo Yuan
Scoliosis is a complex spinal three-dimensional malformation with complicated pathogenesis, often associated with complications as thoracic deformity and shoulder imbalance. Because the acquisition of specimen or animal models are difficult, the biomechanical study of scoliosis is limited. In recent years, along with the development of the computer technology, software and image, the technology of establishing a finite element model of human spine is maturing and it has been providing strong support for the research of pathogenesis of scoliosis, the design and application of brace, and the selection of surgical methods...
April 25, 2018: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29772824/characterization-of-cyclodextrin-volatile-inclusion-complexes-a-review
#17
REVIEW
Miriana Kfoury, David Landy, Sophie Fourmentin
Cyclodextrins (CDs) are a family of cyclic oligosaccharides that constitute one of the most widely used molecular hosts in supramolecular chemistry. Encapsulation in the hydrophobic cavity of CDs positively affects the physical and chemical characteristics of the guests upon the formation of inclusion complexes. Such a property is interestingly employed to retain volatile guests and reduce their volatility. Within this scope, the starting crucial point for a suitable and careful characterization of an inclusion complex is to assess the value of the formation constant (Kf ), also called stability or binding constant...
May 17, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29772777/oxidative-stress-in-preeclampsia-and-placental-diseases
#18
REVIEW
Rajaa Aouache, Louise Biquard, Daniel Vaiman, Francisco Miralles
Preeclampsia is a persistent hypertensive gestational disease characterized by high blood pressure and proteinuria, which presents from the second trimester of pregnancy. At the cellular level, preeclampsia has largely been associated with the release of free radicals by the placenta. Placenta-borne oxidative and nitrosative stresses are even sometimes considered as the major molecular determinants of the maternal disease. In this review, we present the recent literature evaluating free radical production in both normal and pathological placentas (including preeclampsia and other major pregnancy diseases), in humans and animal models...
May 17, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29772760/a-review-of-carbon-nanomaterials-synthesis-via-the-chemical-vapor-deposition-cvd-method
#19
REVIEW
Yehia M Manawi, Ayman Samara, Tareq Al-Ansari, Muataz A Atieh
Carbon nanomaterials have been extensively used in many applications owing to their unique thermal, electrical and mechanical properties. One of the prime challenges is the production of these nanomaterials on a large scale. This review paper summarizes the synthesis of various carbon nanomaterials via the chemical vapor deposition (CVD) method. These carbon nanomaterials include fullerenes, carbon nanotubes (CNTs), carbon nanofibers (CNFs), graphene, carbide-derived carbon (CDC), carbon nano-onion (CNO) and MXenes...
May 17, 2018: Materials
https://www.readbyqxmd.com/read/29772722/ethnobotany-phytochemistry-and-pharmacological-effects-of-plants-in-genus-cynanchum-linn-asclepiadaceae
#20
REVIEW
Lu Han, Xiuping Zhou, Mengmeng Yang, Li Zhou, Xinxin Deng, Shijie Wei, Wenping Wang, Zhizhong Wang, Xue Qiao, Changcai Bai
Genus Cynanchum L. belongs to the family Asclepiadaceae, which comprise more than 200 species distributed worldwide. In Chinese medical practice, numerous drugs (such as tablets and powders) containing different parts of plants of this genus are used to treat snake bites, bruises, osteoblasts, rheumatoid arthritis and tumors. A search for original articles published on the cynanchum genus was performed by using several resources, including Flora of China Official Website and various scientific databases, such as PubMed, SciFinder, the Web of Science, Science Direct, and China Knowledge Resource Integrated (CNKI)...
May 16, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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