keyword
https://read.qxmd.com/read/38631614/use-of-initial-endotracheal-versus-intravenous-epinephrine-during-neonatal-cardiopulmonary-resuscitation-in-the-delivery-room-review-of-a-national-database
#1
JOURNAL ARTICLE
C Halling, S Conroy, T Raymond, E E Foglia, M Haggerty, L L Brown, M H Wyckoff
OBJECTIVE: To assess whether initial epinephrine administration by endotracheal tube (ET) in newly born infants receiving chest compressions and epinephrine in the delivery room is associated with lower rates of return of spontaneous circulation (ROSC) compared with newborns receiving initial intravenous (IV) epinephrine. STUDY DESIGN: We conducted a retrospective review of neonates receiving chest compressions and epinephrine in the delivery room (DR) from the AHA Get With The Guidelines®-Resuscitation registry from October 2013 through July 2020...
April 15, 2024: Journal of Pediatrics
https://read.qxmd.com/read/38596740/revisiting-the-hydrogenation-behavior-of-ndga-and-its-hydride-phases
#2
JOURNAL ARTICLE
Vitalii Shtender, Johan Cedervall, Gustav Ek, Claudia Zlotea, Mikael S Andersson, Pascal Manuel, Martin Sahlberg, Ulrich Häussermann
NdGa hydride and deuteride phases were prepared from high-quality NdGa samples and their structures characterized by powder and single-crystal X-ray diffraction and neutron powder diffraction. NdGa with the orthorhombic CrB-type structure absorbs hydrogen at hydrogen pressures ≤ 1 bar until reaching the composition NdGaH(D)1.1 , which maintains a CrB-type structure. At elevated hydrogen pressure additional hydrogen is absorbed and the maximum composition recovered under standard temperature and pressure conditions is NdGaH(D)1...
April 1, 2024: Journal of Applied Crystallography
https://read.qxmd.com/read/38497706/neurodevelopmental-outcomes-of-extremely-preterm-infants-fed-donor-milk-or-preterm-infant-formula-a-randomized-clinical-trial
#3
COMMENT
Tarah T Colaizy, Brenda B Poindexter, Scott A McDonald, Edward F Bell, Waldemar A Carlo, Susan J Carlson, Sara B DeMauro, Kathleen A Kennedy, Leif D Nelin, Pablo J Sánchez, Betty R Vohr, Karen J Johnson, Dianne E Herron, Abhik Das, Margaret M Crawford, Michele C Walsh, Rosemary D Higgins, Barbara J Stoll, Namisavayam Ambalavanan, Myra H Wyckoff, Carl T D'Angio, George W Bugg, Robin K Ohls, Anne Marie Reynolds, Gregory M Sokol, Abbot R Laptook, Steven L Olsen, Jessica R White, Sudarshan R Jadcherla, Monika Bajaj, Prabhu S Parimi, Barbara Schmidt, Matthew M Laughon, John Barks, Kimberley A Fisher, Anna Maria Hibbs, Myriam Peralta-Carcelen, Noah Cook, Roy J Heyne, Brenna Cavanaugh, Ira Adams-Chapman, Janell Fuller, Michelle E Hartley-McAndrew, Heidi M Harmon, Andrea F Duncan, Abbey C Hines, Howard W Kilbride, Laurie A Richards, Nathalie L Maitre, Girija Natarajan, Andrea N Trembath, Martha D Carlson, William F Malcolm, Deanne E Wilson-Costello
IMPORTANCE: Maternal milk feeding of extremely preterm infants during the birth hospitalization has been associated with better neurodevelopmental outcomes compared with preterm formula. For infants receiving no or minimal maternal milk, it is unknown whether donor human milk conveys similar neurodevelopmental advantages vs preterm formula. OBJECTIVE: To determine if nutrient-fortified, pasteurized donor human milk improves neurodevelopmental outcomes at 22 to 26 months' corrected age compared with preterm infant formula among extremely preterm infants who received minimal maternal milk...
February 20, 2024: JAMA
https://read.qxmd.com/read/38421708/physical-therapists-acceptance-of-a-wearable-fabric-based-sensor-system-motion-tape-for-use-in-clinical-practice-qualitative-focus-group-study
#4
JOURNAL ARTICLE
Audrey Lee, Patricia Dionicio, Emilia Farcas, Job Godino, Kevin Patrick, Elijah Wyckoff, Kenneth J Loh, Sara Gombatto
BACKGROUND: Low back pain (LBP) is a costly global health condition that affects individuals of all ages and genders. Physical therapy (PT) is a commonly used and effective intervention for the management of LBP and incorporates movement assessment and therapeutic exercise. A newly developed wearable, fabric-based sensor system, Motion Tape, uses novel sensing and data modeling to measure lumbar spine movements unobtrusively and thus offers potential benefits when used in conjunction with PT...
February 29, 2024: JMIR Human Factors
https://read.qxmd.com/read/38396053/association-of-maternal-pre-pregnancy-or-first-trimester-body-mass-index-with-neurodevelopmental-impairment-or-death-in-extremely-low-gestational-age-neonates
#5
JOURNAL ARTICLE
Sanjay Chawla, Abbot R Laptook, Emily A Smith, Sylvia Tan, Girija Natarajan, Myra H Wyckoff, Rachel G Greenberg, Namasivayam Ambalavanan, Edward F Bell, Krisa P Van Meurs, Susan R Hintz, Betty R Vohr, Erika F Werner, Abhik Das, Seetha Shankaran
OBJECTIVE: To compare the rates of death or survival with severe neurodevelopmental impairment (sNDI) at 2 years among extremely preterm infants in relation to pre-pregnancy or first-trimester maternal body mass index (BMI). METHODS: This retrospective cohort study included extremely preterm infants (gestational age 220/7 -266/7 weeks). The study was conducted at National Institute of Child Health and Human Development Neonatal Research Network sites. The primary outcome was death or sNDI at 2 years...
February 23, 2024: Journal of Perinatology: Official Journal of the California Perinatal Association
https://read.qxmd.com/read/38388715/social-distancing-and-extremely-preterm-births-in-the-initial-covid-19-pandemic-period
#6
JOURNAL ARTICLE
Vivek V Shukla, Benjamin A Carper, Namasivayam Ambalavanan, Matthew A Rysavy, Edward F Bell, Abhik Das, Ravi M Patel, Carl T D'Angio, Kristi L Watterberg, C Michael Cotten, Stephanie L Merhar, Myra H Wyckoff, Pablo J Sánchez, Neha Kumbhat, Waldemar A Carlo
HYPOTHESIS: Increased social distancing was associated with a lower incidence of extremely preterm live births (EPLB) during the initial COVID-19 pandemic period. STUDY DESIGN: Prospective study at the NICHD Neonatal Research Network sites comparing EPLB (220/7 -286/7 weeks) and extremely preterm intrapartum stillbirths (EPIS) rates during the pandemic period (March-July, weeks 9-30 of 2020) with the reference period (same weeks in 2018 and 2019), correlating with state-specific social distancing index (SDI)...
February 22, 2024: Journal of Perinatology: Official Journal of the California Perinatal Association
https://read.qxmd.com/read/38333123/cadmium-phosphates-cd-2-po-4-oh-and-cd-5-po-4-2-oh-4-crystallizing-in-mineral-structures
#7
JOURNAL ARTICLE
Felix Eder, Matthias Weil
Single crystals of two basic cadmium phosphates, dicadmium orthophosphate hydroxide, Cd2 (PO4 )OH, and penta-cadmium bis-(orthophosphate) tetra-kis-(hydroxide), Cd5 (PO4 )2 (OH)4 , were obtained under hydro-thermal conditions. Cd2 (PO4 )OH adopts the triplite [(Mn,Fe)2 (PO4 )F] structure type. Its asymmetric unit comprises two Cd, one P and five O sites, all situated at the general Wyckoff position 8 f of space group I 2/ a ; two of the O atoms are positionally disordered over two sites, and the H atom could not be localized...
February 1, 2024: Acta Crystallographica. Section E, Crystallographic Communications
https://read.qxmd.com/read/38314860/surveillance-for-selected-pathogens-and-parasites-of-northern-bobwhite-colinus-virginianus-from-western-oklahoma-usa-2018-20
#8
JOURNAL ARTICLE
Seth T Wyckoff, Tell C Judkins, Nicole M Nemeth, Mark G Ruder, James A Martin, Melanie R Kunkel, Kayla B Garrett, Kayla G Adcock, Daniel G Mead, Michael J Yabsley
The Northern Bobwhite (Colinus virginianus) has been undergoing a range-wide population decline. Potential causes for declines across its historic range have been investigated for decades and include habitat loss and fragmentation and a variety of parasitic and infectious diseases. Although there have been studies on bobwhite ecology in Oklahoma, USA, relatively little is known about parasites and pathogens in the region. We evaluated the health of free-ranging bobwhites from nine sites in western Oklahoma...
February 5, 2024: Journal of Wildlife Diseases
https://read.qxmd.com/read/38312165/synthesis-crystal-structure-and-hydrogenation-properties-of-mg-x-li-3%C3%A2-%C3%A2-x-b-48%C3%A2-%C3%A2-y-x-1-11-y-0-40
#9
JOURNAL ARTICLE
Nazar Pavlyuk, Viktoria Milashius, Vasyl Kordan, Volodymyr Pavlyuk
The ternary magnesium/lithium boride, Mg x Li3 -  x B48 -  y ( x = 1.11, y = 0.40, idealized formula MgLi2 B48 ), crystallizes as its own structure type in P 43 21 2, which is closely related to the structural family comprising α-AlB12 , Be0.7 Al1.1 B22 and tetra-gonal β-boron. The asymmetric unit of title structure contains two statistical mixtures Mg/Li in Wyckoff sites 8 b with relative occupancies Mg:Li = 0.495 (9):0.505 (9) and 4 a with Mg:Li = 0.097 (8):0...
January 1, 2024: Acta Crystallographica. Section E, Crystallographic Communications
https://read.qxmd.com/read/38312161/crystal-structure-of-a-water-oxidation-catalyst-solvate-with-composition-nh-4-2-fe-iv-l-6h-%C3%A2-3ch-3-cooh-l-clathrochelate-ligand
#10
JOURNAL ARTICLE
Maksym O Plutenko, Sergii I Shylin, Sergiu Shova, Aleksander V Blinder, Igor O Fritsky
The synthetic availability of mol-ecular water oxidation catalysts containing high-valent ions of 3 d metals in the active site is a prerequisite to enabling photo- and electrochemical water splitting on a large scale. Herein, the synthesis and crystal structure of di-ammonium {μ-1,3,4,7,8,10,12,13,16,17,19,22-dodeca-aza-tetra-cyclo-[8.8.4.13,17 .18,12 ]tetra-cosane-5,6,14,15,20,21-hexa-onato}ferrate(IV) acetic acid tris-olvate, (NH4 )2 [FeIV (C12 H12 N12 O6 )]·3CH3 COOH or (NH4 )2 [FeIV ( L -6H)]·3CH3 COOH is reported...
January 1, 2024: Acta Crystallographica. Section E, Crystallographic Communications
https://read.qxmd.com/read/38299552/-in-silico-approaches-to-assessing-multiple-high-level-drug-drug-and-drug-disease-adverse-drug-effects
#11
REVIEW
Xuan Xu, Jim E Riviere, Shahzad Raza, Nuwan Indika Millagaha Gedara, Remya Ampadi Ramachandran, Lisa A Tell, Gerald J Wyckoff, Majid Jaberi-Douraki
INTRODUCTION: Pharmacovigilance plays a pivotal role in monitoring adverse events (AEs) related to chemical substances in human/animal populations. With increasing spontaneous-reporting systems, researchers turned to in-silico approaches to efficiently analyze drug safety profiles. Here, we review in-silico methods employed for assessing multiple drug-drug/drug-disease AEs covered by comparative analyses and visualization strategies. AREAS COVERED: Disproportionality, involving multi-stage statistical methodologies and data processing, identifies safety signals among drug-AE pairs...
February 1, 2024: Expert Opinion on Drug Metabolism & Toxicology
https://read.qxmd.com/read/38272063/development-of-a-prediction-model-for-surgery-or-early-mortality-at-the-time-of-initial-assessment-for-necrotizing-enterocolitis
#12
JOURNAL ARTICLE
Sujir Pritha Nayak, Mariela Sanchez-Rosado, Jordan D Reis, L Steven Brown, Kate Louise Mangona, Priya Sharma, David Bryan Nelson, Myra Helen Wyckoff, Samir Pandya, Imran N Mir, Luc Brion
BACKGROUND: No available scale, at the time of initial evaluation for necrotizing enterocolitis (NEC), accurately predicts, i.e., with an area under the curve (AUC) ≥ ≥ 0.9, which preterm infants will undergo surgery for NEC stage III or die within a week. METHODS: This is a retrospective cohort study (n=261) of preterm infants <33 weeks' gestation or <1500 grams birthweight with either suspected or with definite NEC born at Parkland Hospital between 2009-2021...
January 25, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38198979/resting-state-functional-magnetic-resonance-imaging-network-association-with-mortality-epilepsy-cognition-and-motor-two-year-outcomes-in-suspected-severe-neonatal-acute-brain-injury
#13
JOURNAL ARTICLE
Varina L Boerwinkle, Iliana Manjón, Bethany L Sussman, Alyssa McGary, Lucia Mirea, Kirsten Gillette, Jordan Broman-Fulks, Emilio G Cediel, Martin Arhin, Senyene E Hunter, Sarah N Wyckoff, Kimberlee Allred, Deborah Tom
BACKGROUND AND OBJECTIVES: In acute brain injury of neonates, resting-state functional magnetic resonance imaging (MRI) (RS) showed incremental association with consciousness, mortality, cognitive and motor development, and epilepsy, with correction for multiple comparisons, at six months postgestation in neonates with suspected acute brain injury (ABI). However, there are relatively few developmental milestones at six months to benchmark against, thus, we extended this cohort study to evaluate two-year outcomes...
March 2024: Pediatric Neurology
https://read.qxmd.com/read/38190155/evaluation-of-a-best-practice-advisory-for-primary-aldosteronism-screening
#14
JOURNAL ARTICLE
Suranut Charoensri, Linda Bashaw, Cheryl Dehmlow, Tammy Ellies, Jennifer Wyckoff, Adina F Turcu
IMPORTANCE: Primary aldosteronism (PA) is a common cause of secondary hypertension and an independent risk factor for cardiovascular morbidity and mortality. Fewer than 2% to 4% of patients at risk are evaluated for PA. OBJECTIVE: To develop and evaluate an electronic health record best-practice advisory (BPA) that assists with PA screening. DESIGN, SETTING, AND PARTICIPANTS: This prospective quality improvement study was conducted at academic center outpatient clinics...
January 8, 2024: JAMA Internal Medicine
https://read.qxmd.com/read/38184864/the-role-and-potential-of-computer-aided-drug-discovery-strategies-in-the-discovery-of-novel-antimicrobials
#15
REVIEW
Samson O Oselusi, Phumuzile Dube, Adeshina I Odugbemi, Kolajo A Akinyede, Tosin L Ilori, Elizabeth Egieyeh, Nicole Rs Sibuyi, Mervin Meyer, Abram M Madiehe, Gerald J Wyckoff, Samuel A Egieyeh
Antimicrobial resistance (AMR) has become more of a concern in recent decades, particularly in infections associated with global public health threats. The development of new antibiotics is crucial to ensuring infection control and eradicating AMR. Although drug discovery and development are essential processes in the transformation of a drug candidate from the laboratory to the bedside, they are often very complicated, expensive, and time-consuming. The pharmaceutical sector is continuously innovating strategies to reduce research costs and accelerate the development of new drug candidates...
January 2, 2024: Computers in Biology and Medicine
https://read.qxmd.com/read/38131363/high-throughput-computational-materials-screening-of-transition-metal-peroxides
#16
JOURNAL ARTICLE
Yin-Hui Peng, Chang-Chun He, Yu-Jun Zhao, Xiao-Bao Yang
Semiconductor materials of abnormal stoichiometric ratio often exhibit unique properties, yet it is still a challenge to determine the structures of such materials in an efficient way. Herein, we propose a method for structurally biased screening according to the coordination numbers and the numbers of Wyckoff positions, balancing the atom local environment and the global symmetry of structures. Based on first-principles calculations, we have predicted two metastable peroxides P 21 / c -ScO2 and Pmmn -TiO3 with more than six coordination points...
December 22, 2023: Physical Chemistry Chemical Physics: PCCP
https://read.qxmd.com/read/38097721/evaluation-of-a-respiratory-care-protocol-including-less-invasive-surfactant-administration-in-preterm-infants
#17
JOURNAL ARTICLE
Christina S Chan, Melody Chiu, Swathi Ariyapadi, L Steven Brown, Patti Burchfield, Valerie Simcik, Kristi Garcia, Kathryn Mazioniene, Mambarambath A Jaleel, Myra H Wyckoff, Vishal S Kapadia, Venkatakrishna Kakkilaya
BACKGROUND: Respiratory care protocol including less invasive śsurfactant administration (LISA) in ≤29 weeks' gestational age (GA) infants introduced in October 2018. METHODS: Retrospective study of infants admitted on continuous positive airway pressure (CPAP) October 2018 to December 2021. Maternal and neonatal variables were compared between infants managed on CPAP with and without LISA. Infants who received LISA and subsequently required mechanical ventilation (MV) within 72 h of life (HOL) [LISA failure (LF)] were compared with those who required no MV [LISA success (LS)]...
December 14, 2023: Pediatric Research
https://read.qxmd.com/read/38066247/impact-of-fetal-inflammatory-response-on-the-severity-of-necrotizing-enterocolitis-in-preterm-infants
#18
JOURNAL ARTICLE
Imran Nazir Mir, Mariela Sánchez-Rosado, Jordan Reis, Naseem Uddin, L Steven Brown, Kate Louise Mangona, David Nelson, Myra Wyckoff, Sujir Pritha Nayak, Luc Brion
OBJECTIVE: Neonates born with fetal inflammatory response (FIR) are at increased risk for adverse neonatal outcomes. Our objective was to determine whether FIR and its severity is associated with severity of necrotizing enterocolitis (NEC) in preterm infants. METHODS: A case-control retrospective study of infants <33 weeks gestational age or <1500 g birthweight, including 260 with stage I-III NEC and 520 controls matched for gestational age. Placental pathology was evaluated, and FIR progression and its severity were defined according to Amsterdam classification...
December 8, 2023: Pediatric Research
https://read.qxmd.com/read/38050771/porous-single-crystalline-centimeter-sized-%C3%AE-al2o3-monoliths-for-selective-and-durable-non-oxidative-dehydrogenation-of-ethane
#19
JOURNAL ARTICLE
Xue Li, Wenting Li, Jie Zhang, Wen Yin, Yuanguang Xia, Kui Xie
Alpha alumina (α-Al2O3) are inert materials with outstanding thermal, chemical and mechanical stability. Herein, we fabricate porous single-crystalline (PSC) α-Al2O3 monoliths at centimeter scale to endow them with high catalytic activity while maintaining their stability. We reduce PSC α-Al2O3 monoliths to create oxygen vacancies in lattice and stabilize them by the ordered lattice to construct unsaturated Al-O coordination structures for enhancing the catalytic activity. The generation of oxygen vacancy at 18e wyckoff position contribute to the unsaturated Al-O coordination...
December 5, 2023: Angewandte Chemie
https://read.qxmd.com/read/38029926/a-novel-receivership-model-for-the-transition-of-young-adults-with-diabetes-experience-from-a-single-center-academic-transition-program
#20
JOURNAL ARTICLE
Jennifer J Iyengar, Lynn Ang, Kathryn Bux Rodeman, Amith Rao, Yu Kuei Lin, David T Broome, Nada Fanous, Rachel B Reinert, Anna Konigsberg, Emily Weatherup, Christine Hagar, Danielle Rogosch, Jacinta Florek, Brittany Carey, Jennifer Wyckoff, Joyce Lee, Inas H Thomas, Scott A Soleimanpour
OBJECTIVE: The transition from pediatric to adult care for young adults with diabetes represents an important but often challenging time characterized by a shift from the family-centered care model of pediatrics to the patient-centered care model of adult medicine. We developed a structured transition program based upon an adult receivership model at a large academic medical center with the goal of improving care coordination and patient satisfaction with the transition process. METHODS: From 2016 to 2020, we implemented a series of quality improvement efforts for young adults age 18-23 with diabetes by incorporating best practices from the American Diabetes Association guidelines on care for emerging adults...
November 27, 2023: Endocrine Practice
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