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https://www.readbyqxmd.com/read/29241349/distribution-and-clustering-of-cutaneous-t-cell-lymphoma-ctcl-cases-in-canada-during-1992-to-2010
#1
Feras M Ghazawi, Elena Netchiporouk, Elham Rahme, Matthew Tsang, Linda Moreau, Steven Glassman, Nathalie Provost, Martin Gilbert, Sara-Elizabeth Jean, Osama Roshdy, Kevin Pehr, Denis Sasseville, Ivan V Litvinov
BACKGROUND: Clustering of patients with cutaneous T-cell lymphoma (CTCL) was reported in several jurisdictions around the world. This rare cancer is known to affect spouses and in some cases multiple members of the same family. These combined results suggest the existence of external disease triggers/promoters. We recently conducted the first comprehensive analysis of CTCL incidence and mortality in Canada, which revealed case clustering in several regions. OBJECTIVES: To extend our previous analysis on CTCL incidence across Canada and to provide all the collected data on CTCL patient incidence in Canada during the period of 1992 to 2010...
December 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29237045/informing-antimicrobial-stewardship-factors-associated-with-inappropriate-antimicrobial-prescribing-in-primary-care
#2
Alexander Singer, Sergio Fanella, Leanne Kosowan, Jamie Falk, Brenden Dufault, Kevin Hamilton, Ashley Walus
Background: Antimicrobial stewardship (AS) programs promote the optimal use of antimicrobials and safe patient care. With most antimicrobials prescribed in the ambulatory setting, establishing benchmark data is imperative to gauge the impact of future AS initiatives. Objectives: To determine the frequency of potentially inappropriate antimicrobial prescribing in primary care practices in Manitoba, Canada and to assess the association between potentially inappropriate antimicrobial prescribing and patient, prescriber and practice-related factors...
December 10, 2017: Family Practice
https://www.readbyqxmd.com/read/29229610/follow-up-imaging-after-nephrectomy-for-cancer-in-canada-urologists-compliance-with-guidelines-an-observational-study
#3
Alice Dragomir, Armen Aprikian, Anil Kapoor, Antonio Finelli, Frédéric Pouliot, Ricardo Rendon, Peter C Black, Ronald Moore, Rodney H Breau, Jun Kawakami, Darrell Drachenberg, Jean-Baptiste Lattouf, Simon Tanguay
BACKGROUND: Surgical tumour removal remains the preferred treatment for most patients with renal cell carcinoma, and many medical associations have proposed guidelines for the optimal surveillance of patients following surgery. This study evaluated the adherence of Canadian urologists to the follow-up guidelines proposed by the Canadian Urological Association (CUA) in 2009. METHODS: The study cohort was identified from the Canadian Kidney Cancer Information System, a prospectively populated database from 15 academic institutions in 6 Canadian provinces: British Colombia, Alberta, Manitoba, Ontario, Quebec and Nova Scotia...
December 11, 2017: CMAJ Open
https://www.readbyqxmd.com/read/29223870/validation-of-an-algorithm-to-detect-severe-ms-relapses-in-administrative-health-databases
#4
James John Marriott, Hui Chen, Randall Fransoo, Ruth Ann Marrie
BACKGROUND: Severe relapses that required treatment were important outcomes in the sentinel trials of disease-modifying therapy (DMT). Identifying such relapses in administrative data would allow comparative-effectiveness studies of DMTs to be conducted in real-world clinical settings. METHODS: All relapsing-remitting (RRMS) and secondary-progressive (SPMS) patients living in Manitoba between 1999 and 2015 were identified using a validated case definition and linkage to the Manitoba MS Clinic database...
December 2, 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29216254/international-classification-of-diseases-icd-coded-obesity-predicts-risk-of-incident-osteoporotic-fracture
#5
Shuman Yang, Lisa M Lix, Lin Yan, Aynslie M Hinds, William D Leslie
International Classification of Diseases (ICD) codes have been used to ascertain individuals who are obese. There has been limited research about the predictive value of ICD-coded obesity for major chronic conditions at the population level. We tested the utility of ICD-coded obesity versus measured obesity for predicting incident major osteoporotic fracture (MOF), after adjusting for covariates (i.e., age and sex). In this historical cohort study (2001-2015), we selected 61,854 individuals aged 50 years and older from the Manitoba Bone Mineral Density Database, Canada...
2017: PloS One
https://www.readbyqxmd.com/read/29214329/time-to-surgery-after-hip-fracture-across-canada-by-timing-of-admission
#6
K J Sheehan, C Filliter, B Sobolev, A R Levy, P Guy, L Kuramoto, J D Kim, M Dunbar, S N Morin, J M Sutherland, S Jaglal, E Harvey, L Beaupre, A Chudyk
The extent of Canadian provincial variation in hip fracture surgical timing is unclear. Provinces performed a similar proportion of surgeries within three inpatient days after adjustment. Time to surgery varied by timing of admission across provinces. This may reflect different approaches to providing access to hip fracture surgery. INTRODUCTION: The aim of this study was to compare whether time to surgery after hip fracture varies across Canadian provinces for surgically fit patients and their subgroups defined by timing of admission...
December 6, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/29202664/suicide-attempts-and-completions-among-mothers-whose-children-were-taken-into-care-by-child-protection-services-a-cohort-study-using-linkable-administrative-data
#7
Elizabeth Wall-Wieler, Leslie L Roos, Marni Brownell, Nathan Nickel, Dan Chateau, Deepa Singal
OBJECTIVE: The objective of this study is to examine suicide attempts and completions among mothers who had a child taken into care by child protection services (CPS). These mothers were compared with their biological sisters who did not have a child taken into care and with mothers who received services from CPS but did not have a child taken into care. METHODS: A retrospective cohort of mothers whose first child was born in Manitoba, Canada, between April 1, 1992, and March 31, 2015, is used...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/29186477/host-specificity-in-subarctic-aphids
#8
Daniel J Gibson, Sarah J Adamowicz, Shoshanah R Jacobs, M Alex Smith
Plants and herbivorous (or parasitic) insects form the majority of macroscopic life. The specificity of interaction between host plant and parasitic insect depends on the adaptations of both the host and the parasite. Over time, these interactions evolve and change as a result of an 'arms race' between host and parasite, and the resulting species-specific adaptations may be maintained, perpetuating these interactions across speciation events. This can lead to specialisation between species or clades. With speciation and species sorting over time, complex interactions evolve...
November 27, 2017: Environmental Entomology
https://www.readbyqxmd.com/read/29182779/phosphine-resistance-in-north-american-field-populations-of-the-lesser-grain-borer-rhyzopertha-dominica-coleoptera-bostrichidae
#9
E Afful, Brent Elliott, Manoj K Nayak, Thomas W Phillips
Phosphine is the most widely used fumigant for stored grain insect pests, and resistance to phosphine has evolved in several species worldwide. This study was designed to determine the presence of phosphine resistance in 34 populations of Rhyzopertha dominica (F.) collected from the United States and Canada. Adult R. dominica were sampled and subjected to a discriminatory dose toxicity assay of exposure to 20 ppm of phosphine for 20 h of exposure to distinguish a susceptible R. dominica adult by death from a resistant beetle that survives the treatment...
November 22, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29178960/the-impact-of-a-physician-detailing-and-sampling-program-for-generic-atorvastatin-an-interrupted-time-series-analysis
#10
Heather C Worthington, Lucy Cheng, Sumit R Majumdar, Steven G Morgan, Colette B Raymond, Stephen B Soumerai, Michael R Law
BACKGROUND: In 2011, Manitoba implemented a province-wide program of physician detailing and free sampling for generic atorvastatin to increase use of this generic statin. We examined the impact of this unique combined program of detailing and sampling for generic atorvastatin on the use and cost of statin medicines, market share of generic atorvastatin, the choice of starting statin for new users, and switching from a branded statin to generic atorvastatin. METHODS: We conducted a retrospective study of Manitoba insurance claims data for all continuously enrolled patients who filled one or more prescriptions for a statin between 2008 and 2013...
November 25, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29178935/estimating-annual-prevalence-of-depression-and-anxiety-disorder-in-multiple-sclerosis-using-administrative-data
#11
Ruth Ann Marrie, Randy Walld, James M Bolton, Jitender Sareen, John R Walker, Scott B Patten, Alexander Singer, Lisa M Lix, Carol A Hitchon, Renée El-Gabalawy, Alan Katz, John D Fisk, Charles N Bernstein
OBJECTIVE: Researchers have developed case definitions to estimate incidence and lifetime prevalence of depression and anxiety disorders in multiple sclerosis (MS) using administrative data. For policymakers however, the prevalence of a disease requiring ongoing treatment during a given period such as annual period prevalence may be more relevant for decision-making. We tested a case definition for annual period prevalence of depression and anxiety disorders in MS using administrative data...
November 25, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29151840/adherence-with-epinephrine-autoinjector-prescriptions-in-primary-care
#12
Elissa M Abrams, Alexander G Singer, Lisa Lix, Alan Katz, Marina Yogendran, F Estelle R Simons
Background: The aim of this study was to estimate primary adherence for epinephrine autoinjector (EA) prescriptions in primary care practices in Manitoba, Canada. Methods: A retrospective analysis of electronic medical record and administrative data was performed to determine primary adherence, defined as dispensation of a new EA prescription within 90 days of the date the prescription was written. Multivariable logistic regression models were used to test predictors of filling an EA prescription...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/29144078/presence-of-household-mold-children-s-respiratory-health-and-school-absenteeism-cause-for-concern
#13
Eleoussa Polyzoi, Dimos Polyzois
A study examining the relationship between housing conditions, respiratory health, and school absenteeism was conducted in the city of Winnipeg in Manitoba, Canada. As part of this study, a survey was completed by 3,424 parents of children in grades 3 and 4 to determine the a) relationship between self-reported visible mold in homes and tested airborne mold; b) relationships of self-reported visible mold, tested airborne mold, and asthma and/or persistent colds; c) school absenteeism rates due to asthma and/or persistent colds; and d) children’s socioeconomic status (SES) and incidence of asthma and/or persistent colds...
March 2017: Journal of Environmental Health
https://www.readbyqxmd.com/read/29140427/sudden-unexpected-cardiac-death-on-monday-in-younger-and-older-men-the-manitoba-follow-up-study
#14
Robert B Tate, Philip D St John
No abstract text is available yet for this article.
November 13, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29138175/statin-prescribing-trends-for-primary-and-secondary-prevention-of-cardiovascular-disease
#15
Felicity Brown, Alexander Singer, Alan Katz, Gerald Konrad
OBJECTIVE: To determine the proportion of patients receiving statins for primary or secondary prevention of cardiovascular disease (CVD), as well as to describe lipid-screening trends. DESIGN: Retrospective chart review using the Manitoba Primary Care Research Network repository. SETTING: Manitoba. PARTICIPANTS: A total of 149 262 patients. MAIN OUTCOME MEASURES: Proportion of patients who were taking statins for primary or secondary prevention of cardiovascular disease (CVD), who did not have evidence of CVD recorded in their charts, and who underwent lipid screening; distribution of statins among age groups; and the proportion of patients eligible for lipid screening when the age cutoffs of the 2012 and 2016 Canadian Cardiovascular Society guidelines were applied...
November 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29128303/the-mountain-of-health-the-perceptions-and-perceived-expectations-of-youth-living-with-type-2-diabetes-in-winnipeg-manitoba-canada-through-a-grounded-theory-study
#16
Elizabeth Huynh
OBJECTIVE: The objective of this study was to explore youth's perceptions of diabetes management. METHODS: The study included 8 Manitoban youth with type 2 diabetes (n=7 girls). Each youth participated in a semistructured interview in person, via Skype or over the phone. The constructivist grounded theory methodologic approach guided the analysis of the data. RESULTS: Discussions about diabetes and health and its management revealed 2 viewpoints: 1) youth's perceptions and 2) youth's perceptions of health-care providers' expectations...
November 8, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29122995/families-first-home-visiting-programme-reduces-population-level-child-health-and-social-inequities
#17
Mariette Chartier, Nathan C Nickel, Dan Chateau, Jennifer E Enns, Michael R Isaac, Alan Katz, Joykrishna Sarkar, Elaine Burland, Carole Taylor, Marni Brownell
BACKGROUND: Home visiting has been shown to reduce child maltreatment and improve child health outcomes. In this observational study, we explored whether Families First, a home visiting programme in Manitoba, Canada, decreased population-level inequities in children being taken into care of child welfare and receiving complete childhood immunisations. METHODS: De-identified administrative health and social services data for children born 2003-2009 in Manitoba were linked to home visiting programme data...
November 9, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29117991/availability-of-naloxone-in-canadian-pharmacies-a-population-based-survey
#18
Alex M Cressman, Graham Mazereeuw, Qi Guan, Wenting Jia, Tara Gomes, David N Juurlink
BACKGROUND: Naloxone is life-saving when administered after opioid overdose. In March 2016, the Canadian government made the antidote available without prescription, but anecdotal reports suggest members of the public have difficulty in procuring it. We examined the availability of naloxone in community pharmacies across Canada. METHODS: We identified community pharmacies in Canada (n = 10 296) and randomly selected 506, stratified using proportionate allocation by population size...
November 8, 2017: CMAJ Open
https://www.readbyqxmd.com/read/29106352/the-oral-health-of-preschool-children-of-refugee-and-immigrant-families-in-manitoba
#19
Mohamed El Azrak, Alice Huang, Khalida Hai-Santiago, Mary F Bertone, Daniella DeMaré, Robert J Schroth
INTRODUCTION: Children of newcomers to Canada have been identified as at moderately high risk for developing early childhood caries (ECC). The purpose of this study was to investigate the oral health of preschool children of refugee and immigrant families in Winnipeg. METHODS: Children < 72 months of age and their parent or primary caregiver were recruited through several newcomer settlement agencies, dental clinics and community programs. Parents and caregivers completed a short questionnaire with the assistance of a research team member...
January 2017: Journal—Canadian Dental Association, Journal de L'Association Dentaire Canadienne
https://www.readbyqxmd.com/read/29102812/results-of-a-utilization-focused-evaluation-of-a-right-to-play-program-for-indigenous-youth
#20
Alexandra Arellano, Tanya Halsall, Tanya Forneris, Cindy Gaudet
This paper presents an evaluation of the Promoting Life Skills for Aboriginal Youth (PLAY) program that is operated by Right to Play (RTP). The focus of the program is to help youth develop a variety of life skills and become leaders within their communities. Piloted in 2010 with 2 communities, the program is now implemented in 88 communities in Ontario, Manitoba, British Columbia, and Alberta. This study applies a utilization-focused evaluation to examine staff perceptions related to program implementation...
August 5, 2017: Evaluation and Program Planning
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