keyword
MENU ▼
Read by QxMD icon Read
search

Cancer mortality epidemiology

keyword
https://www.readbyqxmd.com/read/28729155/incidence-mortality-and-causes-of-death-in-physician-diagnosed-primary-sj%C3%A3-gren-s-syndrome-in-korea-a-nationwide-population-based-study
#1
Hyun Jung Kim, Kyoung Hoon Kim, Hoo Jae Hann, Seungjin Han, Yuri Kim, Sang Hyuk Lee, Dong Sook Kim, Hyeong Sik Ahn
OBJECTIVES: The objective of this study was to investigate the epidemiological features of primary Sjögren's syndrome (pSS) in Korea at a national level, including the incidence, mortality, and causes of death. METHODS: We used a national, population-based registry database called the Rare Intractable Disease Registration Program from the Health Insurance Review and Assessment Service to obtain pSS patient data for the period between 2010 and 2014. pSS was diagnosed by a physician based on uniform criteria...
March 8, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28728748/metastatic-renal-cell-carcinoma-patterns-and-predictors-of-metastases-a-contemporary-population-based-series
#2
Thenappan Chandrasekar, Zachary Klaassen, Hanan Goldberg, Girish S Kulkarni, Robert J Hamilton, Neil E Fleshner
OBJECTIVE: To assess the patterns and predictors of metastatic disease in renal cell carcinoma (RCC) at the time of diagnosis in a contemporary series. METHODS: The Surveillance, Epidemiology, and End Results database was queried for all patients with kidney RCC from 2010 to 2013 (N = 50,815). Distribution and predictors of distant metastases at diagnosis were assessed. Multivariate logistic regression hazard analyses were performed to determine covariates associated with the likelihood of having metastases at diagnosis, whereas competing risks regression analysis was used to assess predictors of cancer-specific mortality (CSM) in patients with metastatic disease...
July 17, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28728168/lung-cancer-prognostic-index-a-risk-score-to-predict-overall-survival-after-the-diagnosis-of-non-small-cell-lung-cancer
#3
Marliese Alexander, Rory Wolfe, David Ball, Matthew Conron, Robert G Stirling, Benjamin Solomon, Michael MacManus, Ann Officer, Sameer Karnam, Kate Burbury, Sue M Evans
INTRODUCTION: Non-small-cell lung cancer outcomes are poor but heterogeneous, even within stage groups. To improve prognostic precision we aimed to develop and validate a simple prognostic model using patient and disease variables. METHODS: Prospective registry and study data were analysed using Cox proportional hazards regression to derive a prognostic model (hospital 1, n=695), which was subsequently tested (Harrell's c-statistic for discrimination and Cox-Snell residuals for calibration) in two independent validation cohorts (hospital 2, n=479 and hospital 3, n=284)...
July 20, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28721887/external-beam-radiation-therapy-with-a-brachytherapy-boost-versus-radical-prostatectomy-in-gleason-pattern-5-prostate-cancer-a-population-based-cohort-study
#4
Chenyang Wang, Amar U Kishan, Mitchell Kamrava, Michael L Steinberg, Christopher R King
PURPOSE: Patients with prostate cancer (PCa) containing Gleason pattern (GP) 5 disease experience a greater and earlier incidence of prostate cancer-specific mortality (PCSM) than general PCa patients. This affords the statistical power to compare PCSM outcomes among different treatment modalities even when restricting the analysis to patients treated in the modern era. The purpose of the present study was to compare the survival outcomes among patients with GP 5 PCa on needle core biopsy or transurethral resection of the prostate who underwent extremely dose-escalated radiation therapy (RT; exemplified by external beam RT with a brachytherapy boost [EBRT + BT]) versus radical prostatectomy (RP) in the modern era...
August 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28717246/estimating-utility-weights-and-quality-adjusted-life-year-loss-for-colorectal-cancer-related-health-states-in-korea
#5
Jin Yong Lee, Minsu Ock, Min-Woo Jo, Woo-Seung Son, Hyeon-Jeong Lee, Seon-Ha Kim, Hyun Joo Kim, Jong Lyul Lee
We aimed to assess utility weight of health states associated with colorectal cancer (CRC) that reflect the societal preference of the Korean population and to estimate the quality-adjusted life year (QALY) loss with CRC. We recruited 607 individuals from the Korean population; they were surveyed via face-to-face computer-assisted interviews. The participants evaluated each CRC-associated health state using standard gamble. Utility weight for each health state was calculated as the possibility of full health restoration...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28717119/nephron-sparing-surgery-has-better-oncologic-outcomes-than-extirpative-nephrectomy-in-t1a-but-not-in-t1b-or-t2-stage-renal-cell-carcinoma
#6
You Luo, San-San Chen, Liang Bai, Li Luo, Xiang-Guang Zheng, Sen Wang
BACKGROUND The aim of this study was to investigate the benefit of nephron sparing surgery (NSS) compared with extirpative nephrectomy in different tumor stages of renal cell carcinoma. MATERIAL AND METHODS We reviewed the Surveillance, Epidemiology and End Results (SEER) database for NSS and extirpative nephrectomy in localized (stages T1-2N0M0) renal cell carcinoma diagnosed after 2004. We used the variable screening function of the SEER database to identified 55,947 cases that met inclusion and exclusion criteria for survival analysis...
July 18, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28716307/should-epithelial-ovarian-carcinoma-metastatic-to-the-inguinal-lymph-nodes-be-assigned-stage-ivb
#7
Dimitrios Nasioudis, Eloise Chapman-Davis, Melissa K Frey, Thomas A Caputo, Steven S Witkin, Kevin Holcomb
OBJECTIVE: According to the revised FIGO staging system women with ovarian carcinoma and inguinal lymph node (LN) metastases, formerly stage III, are now considered stage IVB. In this study we compare their survival to that of women with stage III and stage IV disease. METHODS: Women diagnosed with epithelial ovarian carcinoma were drawn from the Surveillance, Epidemiology, and End Results database (2004-2013). Four groups were formed: group 1 (stage IV due to positive inguinal nodes), group 2 (stage III with positive para-aortic/pelvic nodes), group 3 (stage IV with positive distant nodes) and group 4 (stage IV with distant metastases)...
July 14, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28712791/radiotherapy-for-stage-i-and-ii-testicular-seminomas-secondary-malignancies-and-survival
#8
Hiten D Patel, Arnav Srivastava, Ridwan Alam, Gregory A Joice, Zeyad R Schwen, Alice Semerjian, Mohamad E Allaf, Phillip M Pierorazio
INTRODUCTION: Testicular seminoma affects relatively young men with excellent survival outcomes. There has been increasing concern that radiotherapy (RT) leads to secondary malignant neoplasms (SMNs) and subsequent mortality. We evaluated the effect of RT on incidence of SMNs and quantified cancer-related mortality and other causes of death for patients with stage I and II testicular seminoma. MATERIAL AND METHODS: A national sample of men (1988-2013) diagnosed with stage IA/IB/IS/IIA/IIB/IIC testicular seminomas from Surveillance, Epidemiology, and End Results were evaluated...
July 13, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28712615/predicting-real-world-effectiveness-of-cancer-therapies-using-overall-survival-and-progression-free-survival-from-clinical-trials-empirical-evidence-for-the-asco-value-framework
#9
Darius N Lakdawalla, Jason Shafrin, Ningqi Hou, Desi Peneva, Seanna Vine, Jinhee Park, Jie Zhang, Ron Brookmeyer, Robert A Figlin
OBJECTIVES: To measure the relationship between randomized controlled trial (RCT) efficacy and real-world effectiveness for oncology treatments as well as how this relationship varies depending on an RCT's use of surrogate versus overall survival (OS) endpoints. METHODS: We abstracted treatment efficacy measures from 21 phase III RCTs reporting OS and either progression-free survival or time to progression endpoints in breast, colorectal, lung, ovarian, and pancreatic cancers...
July 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28712528/breast-cancer-in-the-21st-century-from-early-detection-to-new-therapies
#10
J A Merino Bonilla, M Torres Tabanera, L H Ros Mendoza
The analysis of the causes that have given rise to a change in tendency in the incidence and mortality rates of breast cancer in the last few decades generates important revelations regarding the role of breast screening, the regular application of adjuvant therapies and the change of risk factors. The benefits of early detection have been accompanied by certain adverse effects, even in terms of an excessive number of prophylactic mastectomies. Recently, several updates have been published on the recommendations in breast cancer screening at an international level...
July 13, 2017: Radiología
https://www.readbyqxmd.com/read/28709663/pulmonary-resection-for-second-lung-cancer-after-pneumonectomy-a-population-based-study
#11
Adil Ayub, Sadiq S Rehmani, Adnan M Al-Ayoubi, Wissam Raad, Raja M Flores, Faiz Y Bhora
BACKGROUND: Pulmonary resection for a second lung cancer after pneumonectomy is generally considered to be at prohibitive risk. Using a population-based database, we examined treatment patterns and survival in patients who underwent pulmonary resection after pneumonectomy for lung cancer. METHODS: We queried the Surveillance, Epidemiology, and End Results (SEER) database (1988-2012) to identify patients who underwent pneumonectomy and subsequently experienced contralateral non-small cell lung cancer (NSCLC)...
July 11, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28709441/mortality-outcomes-of-low-dose-computed-tomography-screening-for-lung-cancer-in-urban-china-a-decision-analysis-and-implications-for-practice
#12
Zixing Wang, Wei Han, Weiwei Zhang, Fang Xue, Yuyan Wang, Yaoda Hu, Lei Wang, Chunwu Zhou, Yao Huang, Shijun Zhao, Wei Song, Xin Sui, Ruihong Shi, Jingmei Jiang
BACKGROUND: Mortality outcomes in trials of low-dose computed tomography (CT) screening for lung cancer are inconsistent. This study aimed to evaluate whether CT screening in urban areas of China could reduce lung cancer mortality and to investigate the factors that associate with the screening effect. METHODS: A decision tree model with three scenarios (low-dose CT screening, chest X-ray screening, and no screening) was developed to compare screening results in a simulated Chinese urban cohort (100,000 smokers aged 45-80 years)...
July 14, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28708937/malignant-central-nervous-system-tumors-among-adolescents-and-young-adults-15-39-years-old-in-14-southern-eastern-european-registries-and-the-us-surveillance-epidemiology-and-end-results-program-mortality-and-survival-patterns
#13
Marios K Georgakis, Paraskevi Papathoma, Anton Ryzhov, Snezana Zivkovic-Perisic, Sultan Eser, Łukasz Taraszkiewicz, Mario Sekerija, Tina Žagar, Luis Antunes, Anna Zborovskaya, Joana Bastos, Margareta Florea, Daniela Coza, Anna Demetriou, Domenic Agius, Rajko M Strahinja, Marios Themistocleous, Maria Tolia, Spyridon Tzanis, George A Alexiou, Panagiotis G Papanikolaou, Panagiotis Nomikos, Maria Kantzanou, Nick Dessypris, Apostolos Pourtsidis, Eleni T Petridou
BACKGROUND: Unique features and worse outcomes have been reported for cancers among adolescents and young adults (AYAs; 15-39 years old). The aim of this study was to explore the mortality and survival patterns of malignant central nervous system (CNS) tumors among AYAs in Southern-Eastern Europe (SEE) in comparison with the US Surveillance, Epidemiology, and End Results (SEER) program. METHODS: Malignant CNS tumors diagnosed in AYAs during the period spanning 1990-2014 were retrieved from 14 population-based cancer registries in the SEE region (n = 11,438)...
July 14, 2017: Cancer
https://www.readbyqxmd.com/read/28708790/trends-of-gynecological-cancers-in-turkey-towards-europe-or-asia
#14
Murat Gultekin, Irem Kucukyildiz, Mujdegul Zayifoglu Karaca, Selin Dundar, Guledal Boztas, Semra Hatice Turan, Ezgi Hacikamiloglu, Bekir Keskinkilic
OBJECTIVE: The aim of this study was to evaluate nationwide gynecological cancer trends in Turkey. METHODS: National cancer registry data (2009-2013) of Turkish Ministry of Health were evaluated. Ovarian, cervical, endometrial, vulvar, vaginal, and tubal cancers are evaluated with respect to age of diagnosis, incidence rates within years, stage, histological distributions, and mortality rates. Data were collected from active cancer registry centers, which increased from 23% in 2009 to 47...
July 13, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28706207/the-influence-of-marital-status-on-survival-of-gallbladder-cancer-patients-a-population-based-study
#15
Xinxing Li, Ye Liu, Yi Wang, Canping Ruan, Haolu Wang, Xiaowen Liang, Yanping Sun, Zhiqian Hu
Marital status has been found to be a prognostic factor for survival in various cancers, but its role in gallbladder cancer (GBC) has not been fully studied. In this study, we used the Surveillance, Epidemiology, and End Results Program (SEER)-registered database to analyze the survival of GBC patients with different marital status. A total of 6,627 GBC patients were selected from SEER database from 2004 to 2013. The age, race, grade, histologic type, AJCC stage, SEER stage and marital status were identified as independent prognostic factors...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28705001/epidemiology-of-pancreatic-adenocarcinoma
#16
Priya K Simoes, Sara H Olson, Amethyst Saldia, Robert C Kurtz
Pancreatic ductal adenocarcinoma is one of the most lethal cancers worldwide. The highest incidence rates her found are in North America and in Western Europe while lower rates in Asian Africa, with age standard incidence rates of 7.2 and 2.8 per 100,000 populations. Unfortunately the vast majority of individuals with pancreatic cancer present with symptoms, and once symptoms develop the chance for surgery is only about 20%. Additionally he incidence rate and mortality from pancreatic ductal adenocarcinoma in the United States shows a very close association suggesting that her earlier detection and treatment does little to change the outcome from this disease...
June 2017: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/28704326/single-marital-status-and-infectious-mortality-in-women-with-cervical-cancer-in-the-united-states
#17
Hiroko Machida, Sarah E Eckhardt, Antonio V Castaneda, Erin A Blake, Huyen Q Pham, Lynda D Roman, Koji Matsuo
OBJECTIVE: Unmarried status including single marital status is associated with increased mortality in women bearing malignancy. Infectious disease weights a significant proportion of mortality in patients with malignancy. Here, we examined an association of single marital status and infectious mortality in cervical cancer. METHODS: This is a retrospective observational study examining 86,555 women with invasive cervical cancer identified in the Surveillance, Epidemiology, and End Results Program between 1973 and 2013...
July 19, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28702373/murine-pancreatic-acinar-cell-carcinoma-growth-kinetics-are-independent-of-dietary-vitamin-d-deficiency-or-supplementation
#18
James Dooley, Vasiliki Lagou, Nathalie Heirman, Tom Dresselaers, Uwe Himmelreich, Adrian Liston
Vitamin D has been proposed as a therapeutic strategy in pancreatic cancer, yet evidence for an effect of dietary vitamin D on pancreatic cancer is ambiguous, with conflicting data from human epidemiological and intervention studies. Here, we tested the role of dietary vitamin D in the in vivo context of the well-characterized Ela1-TAg transgenic mouse model of pancreatic acinar cell carcinoma. Through longitudinal magnetic resonance imaging of mice under conditions of either dietary vitamin D deficiency (<5 IU/kg vitamin D) or excess (76,500 IU/kg vitamin D), compared to control diet (1,500 IU/kg vitamin D), we measured the effect of variation of dietary vitamin D on tumor kinetics...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28699797/candidemia-and-invasive-candidiasis-among-hospitalized-neonates-and-pediatric-patients
#19
Rachel Harrington, Sylvia L Kindermann, Qingjiang Hou, Robert J Taylor, Nkechi Azie, David L Horn
OBJECTIVE: To investigate the epidemiology, treatment, length of stay (LOS) and costs for neonatal and pediatric inpatients with invasive candidiasis (IC). METHODS: The Cerner Health Facts Database was used to assess inpatients (2005-2014) identified by positive blood or cerebrospinal fluid (CSF) Candida cultures. Log-transformed LOS and cost were examined in candidemia-only patients (n= 191) using multivariable linear regression. RESULTS: 202 patients had a positive culture (blood: n = 192; CSF: n = 10; both: n = 2)...
July 12, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28699133/survival-rates-for-patients-with-resected-gastric-adenocarcinoma-finally-have-increased-in-the-united-states
#20
Elliot G Arsoniadis, Schelomo Marmor, Gustave K Diep, Jane Yuet Ching Hui, Eric H Jensen, Todd M Tuttle
BACKGROUND: In the United States, the overall survival rates for gastric adenocarcinoma have remained low, with surgical resection as the only therapy for many patients. Given the advances in multimodality treatment and the development of guidelines recommending adequate lymph node evaluation, the authors determined whether overall survival rates for patients with gastric adenocarcinoma have increased in the United States. METHODS: The study used the Surveillance Epidemiology and End Results (SEER) database to examine overall survival for patients with the diagnosis of gastric adenocarcinoma between 1988 and 2013...
July 11, 2017: Annals of Surgical Oncology
keyword
keyword
22651
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"