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https://www.readbyqxmd.com/read/28523365/outcome-from-5-year-live-surgical-demonstrations-in-urinary-stone-treatment-are-outcomes-compromised
#1
Jaap D Legemate, Stefano P Zanetti, Joyce Baard, Guido M Kamphuis, Emanuele Montanari, Olivier Traxer, Jean Jmch de la Rosette
PURPOSE: To compare intra- and post-operative outcomes of endourological live surgical demonstrations (LSDs) and routine surgical practice (RSP) for urinary stones. METHODS: Consecutive ureterorenoscopic (URS) and percutaneous (PNL) urinary stone procedures over a 5-year period were reviewed. Procedures were divided into LSDs and RSP. Differences between the groups were separately analysed for URS and PNL. Primary outcomes included intra- and post-operative complication rates and grades...
May 18, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28498511/enhanced-antitumor-effect-of-targeted-nanoliposomal-bleomycin
#2
Mohsen Chiani, Kayhan Azadmanesh, Mohammad Ali Shokrgozar, Mohammad Reza Mehrabi, Azim Akbarzadeh, Dariush Norouzian
Folate receptor (FR)-mediated drug delivery is a promising approach for active targeting of drugs to the FR-positive tumor cells. Bleomycin (BLM) is an antitumor antibiotic with poor therapeutic activity as a result of its limited diffusion into tumor cells. The aim of this study was to investigate whether FR-targeted PEGylated nanoliposomes (FPNL) can effectively deliver BLM to tumor cells and enhance its in vitro and in vivo efficacy. FPNL and PNL (non-targeted) were prepared by thin film hydration method and their physiochemical properties, cellular uptake, tissue distribution and tumor inhibitory effects were investigated...
May 12, 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/28359409/surgical-management-of-urinary-stones-with-abnormal-kidney-anatomy
#3
Giray Ergin, Mustafa Kirac, Ali Unsal, Burak Kopru, Mustafa Yordam, Hasan Biri
In spite of the fact that urologic surgical techniques used by urologists are becoming more and more minimally invasive and easier because of developing technologies, surgical approaches for the urinary stones in kidneys with abnormal anatomy are still confusing. The objective of this article is to determine the treatment options in these kidneys. For this purpose, between 2005 and 2015, we retrospectively evaluated patients operated for urolithiasis with various congenital renal anomalies in five referral urology clinics in our country...
April 2017: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/28357451/comparison-of-supine-and-prone-positions-for-percutaneous-nephrolithotomy-in-treatment-of-staghorn-stones
#4
Mehmet İlker Gökce, Arif Ibiş, Adem Sancı, Aykut Akıncı, Uygar Bağcı, Eylül Asya Ağaoğlu, Evren Süer, Ömer Gülpınar
INTRODUCTION: Percutaneous nephrolithotomy (PNL) is the primary treatment modality for management of staghorn stones. PNL in supine position has important advantages over prone positon. However, studies comparing prone and supine positions for PNL in staghorn stone patients have conflicting results, and the aim of the current study was to compare prone and supine positions for PNL in staghorn stone cases. PATIENTS AND METHODS: Data of patients underwent PNL for staghorn stones in supine or prone position by a single urologist were collected prospectively...
March 29, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28351191/acute-kidney-injury-after-percutaneous-nephrolithotomy-for-stones-in-solitary-kidneys
#5
Ahmed R El-Nahas, Diaa-Eldin Taha, Hussien M Ali, Ahmed M Elshal, Mohamed H Zahran, Nasr A El-Tabey, Ahmed M El-Assmy, Ahmed M Harraz, Hazem E Moawad, Mahmoud M Othman
OBJECTIVES: The aim of this study was to report the incidence, severity, outcome and risk factors of acute kidney injury (AKI) following percutaneous nephrolithotomy (PNL) in solitary kidneys. METHODS: The study included consecutive adult patients who underwent PNL for treatment of calculi in a solitary kidney between May 2012 and July 2015. Patients with congenital renal anomalies or with stages 4 and 5 chronic kidney disease (CKD) were excluded. Serum creatinine levels were measured the day before PNL, daily after PNL for 2-5 days and after 3 months...
March 29, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28255416/the-effects-of-previous-open-renal-stone-surgery-types-on-pnl-outcomes
#6
Faruk Ozgor, Onur Kucuktopcu, Burak Ucpinar, Omer Sarilar, Akif Erbin, Fatih Yanaral, Murat Sahan, Murat Binbay
INTRODUCTION: Our aim was to demonstrate the effect of insicion of renal parenchyma during open renal stone surgery (ORSS) on percutaneous nephrolithotomy (PNL) outcomes. METHODS: Patients with history of ORSS who underwent PNL operation between June 2005 and June 2015 were analyzed retrospectively. Patients were divided into two groups according to their type of previous ORSS. Patients who had a history of ORSS with parenchymal insicion, such as radial nephrotomies, anatrophic nephrolithotomy, lower pole resection, and partial nephrectomy, were included in Group 1...
July 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28253070/comparison-of-retrograde-intrarenal-surgery-and-percutaneous-nephrolithotomy-methods-in-treatment-of-upper-calyceal-stones-of-10-20%C3%A2-mm
#7
Volkan Selmi, Ismail Nalbant, Ufuk Ozturk, Can Tuygun, Hasan Nedim Goksel Goktug, Muhammed Abdurrahim Imamoglu
OBJECTIVE: To compare the success and complication rates and advantages and disadvantages of retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PNL) methods for the upper calyceal renal stones between 10 and 20 mm. MATERIALS AND METHODS: The files of 124 patients who had upper calyceal renal stones in diameter 10-20 mm were analyzed retrospectively. Sixty-one patients were randomized as Group 1 and 63 as Group 2. The parameters as success and complication rates, fluoroscopy and operation times, preoperative and postoperative hemogram (Hb) levels, and need of blood transfusion were saved and then groups compared...
March 2, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28248037/-prospects-for-using-biological-markers-in-various-types-of-urinary-stone-lithotripsy
#8
M M Kutluev, I L Pulin, A Ya Ryakhov, K S Mochalov, R R Farkhutdinov
AIM: To investigate the feasibility of using biological markers for determining the optimal timing to repeat lithotripsy of urinary stones. MATERIALS AND METHODS: This was a prospective, randomized, single-center cohort study of 100 patients randomized into 4 groups. Patients of group I (n=46), II (n=20), III (n=18) and IV (n=16) were used contact lithotripsy (URS), ESWL, PNL, combined lithotripsy. In all patients, before surgery and at 1, 7, 14, 20 days after lithotripsy, iron-induced urine chemiluminescence was measured to determine the level of reactive oxygen species (ROS) and concentration of medium-mass molecules (MMM) in urine...
December 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28247667/-ultraminipercutaneous-nephrolithotripsy-in-treating-kidney-stones
#9
A G Martov, S V Dutov, A S Andronov
INTRODUCTION: Percutaneous nephrolithotripsy (PNL) is the recommended method of surgical treatment of kidney stones of size greater than 2 cm. Trends in the development of modern urology have been steadily toward less traumatic method to treat nephrolithiasis - minimally invasive PNL. The present work aimed to explore of the possibilities of one of the modern variants of minimally invasive PNL - ultra-mini-PNL in treating nephrolithiasis. MATERIALS AND METHODS: The study included 60 patients (mean age 45...
April 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28247629/-percutaneous-nephrolithotripsy-in-patients-after-different-methods-of-urinary-diversion
#10
B G Guliev, E O Stetsik
The study presents the results of percutaneous nephrolithotripsy (PNL) in patients who underwent different methods of urinary diversion. MATERIALS AND METHODS: The study included the results of PNL in 16 patients (study group) with kidney stones who were subjected to different methods of urinary diversion. Earlier, 2 (12.5%) patients underwent bilateral ureterosigmoidostomy for bladder exstrophy, 12 (75%) experienced radical cystectomy with orthotopic ileocystoplasty and 2 (12.5%) - heterotopic cystoplasty...
August 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28237786/tract-sizes-in-miniaturized-percutaneous-nephrolithotomy-a-systematic-review-from-the-european-association-of-urology-urolithiasis-guidelines-panel
#11
Yasir Ruhayel, Abdulkadir Tepeler, Saeed Dabestani, Steven MacLennan, Aleš Petřík, Kemal Sarica, Christian Seitz, Andreas Skolarikos, Michael Straub, Christian Türk, Yuhong Yuan, Thomas Knoll
CONTEXT: Miniaturized instruments for percutaneous nephrolithotomy (PNL), utilizing tracts sized ≤22 Fr, have been developed in an effort to reduce the morbidity and increase the efficiency of stone removal compared with standard PNL (>22 Fr). OBJECTIVE: We systematically reviewed all available evidence on the efficacy and safety of miniaturized PNL for removing renal calculi. EVIDENCE ACQUISITION: The review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement...
February 22, 2017: European Urology
https://www.readbyqxmd.com/read/28221153/ultra-mini-pnl-ump-material-indications-technique-advantages-and-results
#12
Janak D Desai
Stone disease has afflicted mankind since centuries; records from ancient civilisations of India and Egypt have shown stones in human bodies. The scientific mind of humans has always made smart endeavours to remove the kidney stones. From large instruments made like the beaks of different animals and birds in 600 BC (Indian civilisation) to extremely sophisticated and miniaturised endoscopic intruments of today the human race has travelled a long way. The theme has always been to remove the stones with minimal morbidity and mortality and with minimum pain to the patient...
January 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28216931/predictors-of-radiation-exposure-to-providers-during-percutaneous-nephrolithotomy
#13
David L Wenzler, Joel E Abbott, Jeannie J Su, William Shi, Richard Slater, Daniel Miller, Michelle J Siemens, Roger L Sur
BACKGROUND: Limited studies have reported on radiation risks of increased ionizing radiation exposure to medical personnel in the urologic community. Fluoroscopy is readily used in many urologic surgical procedures. The aim of this study was to determine radiation exposure to all operating room personnel during percutaneous nephrolithotomy (PNL), commonly performed for large renal or complex stones. MATERIALS AND METHODS: We prospectively collected personnel exposure data for all PNL cases at two academic institutions...
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28124870/rigid-only-versus-combined-rigid-and-flexible-percutaneous-nephrolithotomy-pnl-a-systematic-review
#14
Cecilia M Cracco, Thomas Knoll, Evangelos N Liatsikos, Palle J Osther, Arthur D Smith, Roberto M Scarpa, Cesare M Scoffone
INTRODUCTION: Percutaneous nephrolithotomy (PNL) is usually performed worldwide with a rigid-only antegrade approach. Daily practice suggests that adding flexible nephroscopy and/or ureteroscopy to conventional rigid PNL might improve its efficacy and safety, but available evidence is weak. Appraisal of reliable outcomes of such PNL techniques would better guide intraoperative choices and optimize surgical results. Therefore our objective was to systematically review relevant literature comparing the outcomes of rigid-only PNL and combined flexible PNLs (adding flexible nephroscopy and/or flexible ureteroscopy) for the treatment of large and/or complex upper urinary tract calculi, with regard to efficacy and safety...
January 26, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28116738/a-comparison-of-retrograde-intrarenal-surgery-and-percutaneous-nephrolithotomy-for-management-of-renal-stones-2-cm
#15
COMPARATIVE STUDY
Sercan Sari, Hakki Ugur Ozok, Mehmet Caglar Cakici, Harun Ozdemir, Okan Bas, Nihat Karakoyunlu, Levent Sagnak, Aykut Bugra Senturk, Hamit Ersoy
PURPOSE: In this retrospective study, we aimed to compare the outcomes in patients who have been treated withpercutaneous nephrolithotomy (PNL) and retrograde intrarenal surgery (RIRS) on renal stones ≥ 2 cm size. MATERIALS AND METHODS: We evaluated patients who underwent PNL or RIRS for renal stones ≥ 2 cm size betweenNovember 2011 and November 2014. Stone size, operation, fluoroscopy and hospitalization time, success rates,stone-free rates and complication rates were compared in both groups...
January 18, 2017: Urology Journal
https://www.readbyqxmd.com/read/28108324/the-circle-nephrostomy-tube-an-attractive-nephrostomy-drainage-system-following-complex-percutaneous-nephrolithotomy
#16
Marawan M El Tayeb, Michael S Borofsky, James E Lingeman
OBJECTIVE: To describe our experience with the circle nephrostomy tube (NT) (Cook Medical), a drainage system uniquely designed for use after multiple-access percutaneous nephrolithotomy (PNL). METHODS: A retrospective review of 1317 consecutive patients undergoing 1599 PNLs at IU Health Methodist Hospital was performed. All multiple access cases utilizing circle NTs were reviewed and analyzed. The method of insertion of circle NT was demonstrated. RESULTS: A total of 1843 accesses were obtained in 1599 renal units (RUs): 380 upper pole, 129 interpolar, and 1334 lower pole...
May 2017: Urology
https://www.readbyqxmd.com/read/28089928/improved-catalytic-properties-of-penicillium-notatum-lipase-immobilized-in-nanoscale-silicone-polymeric-films
#17
Saima Rehman, Ping Wang, Haq Nawaz Bhatti, Muhammad Bilal, Muhammad Asgher
Lipases are one of the most proficient biocatalysts having enormous biotechnological prospective. Immobilization offers a potential solution to improve the stability and recycling characteristics of lipases. An extracellular lipase from Penicillium notatum (PNL) was immobilized in silicon polymers (SiP) through entrapment, and subsequently coated this matrix on the network of fibers in the sponges. The silicone polymers-immobilized lipase (SiP-lipase) displayed highest apparent activity and entrapment efficiency of 1...
April 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28072605/oxytocin-alleviates-orofacial-mechanical-hypersensitivity-associated-with-infraorbital-nerve-injury-through-vasopressin-1a-receptors-of-the-rat-trigeminal-ganglia
#18
Asako Kubo, Masamichi Shinoda, Ayano Katagiri, Mamoru Takeda, Tatsuro Suzuki, Junichi Asaka, David C Yeomans, Koichi Iwata
Oxytocin (OXT) is a neuropeptide hormone synthesized and secreted by hypothalamic neurons and has been reported to play a significant role in pain modulation. However, the mechanisms underlying OXT's antinociceptive effect on neuropathic pain are not fully understood. In this study, we examined the peripheral effect of OXT on mechanical hypersensitivity induced by partial ligation of the infraorbital nerve (PNL) in rats. Mechanical hypersensitivity in the whisker pad skin after PNL was attenuated by the direct administration of OXT into the trigeminal ganglion (TG)...
April 2017: Pain
https://www.readbyqxmd.com/read/28013344/residual-stones-after-percutaneous-nephrolithotomy-comparison-of-intraoperative-assessment-and-postoperative-non-contrast-computerized-tomography
#19
Ahmed M Harraz, Yasser Osman, Ahmed R El-Nahas, Amr A Elsawy, Islam Fakhreldin, Osama Mahmoud, Ahmed El-Assmy, Ahmed A Shokeir
OBJECTIVES: To compare the intraoperative surgeon perspective for detection of residual fragments (RFs) after percutaneous nephrolithotomy (PNL) with postoperative NCCT. METHODS: A prospective study of adult patients who underwent PNL between March and September 2014 was conducted. Stone complexity was evaluated using the Guy's stone score (GSS). All patients were evaluated by pre- and postoperative NCCT. After the procedure, the surgeon had been asked whether there were residual stones or not...
December 24, 2016: World Journal of Urology
https://www.readbyqxmd.com/read/27986574/mammography-before-and-after-bariatric-surgery
#20
Tara E Mokhtari, Ulysses S Rosas, John R Downey, Kanae K Miyake, Debra M Ikeda, John M Morton
BACKGROUND: Morbidly obese women are at increased risk for breast cancer, and the majority of surgical weight-loss patients are older than 40 years old. OBJECTIVE: The purpose of the present study was to determine the technical and interpretive changes in mammography following bariatric surgery. SETTING: Accredited Academic Hospital. METHODS: Two breast-imaging radiologists reviewed screening mammograms performed on 10 morbidly obese women undergoing bariatric surgery both pre- and postoperatively...
October 31, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
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