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https://www.readbyqxmd.com/read/28646306/evaluation-of-stone-volume-distribution-in-renal-collecting-system-as-a-predictor-of-stone-free-rate-after-percutaneous-nephrolithotomy-a-retrospective-single-center-study
#1
Hasan Anıl Atalay, Lutfi Canat, Recep Bayraktarlı, Ilter Alkan, Osman Can, Fatih Altunrende
We analyzed our stone-free rates of PNL with regard to stone burden and its ratio to the renal collecting system volume. Data of 164 patients who underwent PNL were analyzed retrospectively. Volume segmentation of renal collecting system and stones were done using 3D segmentation software with the images obtained from CT data. Analyzed stone volume (ASV) and renal collecting system volume (RCSV) were measured and the ASV-to-RCSV ratio was calculated after the creation of a 3D surface volume rendering of renal stones and the collecting system...
June 23, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28645773/abc-protein-cgabcf2-is-required-for-asexual-and-sexual-development-appressorial-formation-and-plant-infection-in-colletotrichum-gloeosporioides
#2
Zongshan Zhou, Jianyuan Wu, Meiyu Wang, Junxiang Zhang
ATP-binding cassette (ABC) proteins are exclusively found in both prokaryotes and eukaryotes. In this study, we have characterized a gene from Glomerella leaf spot pathogen Colletotrichum gloeosporioides that encodes an ABC protein, whose function to date remains unknown. We designated this gene as CgABCF2. Deletion of CgABCF2 showed drastic reduction both growing rate and conidial production in C. gloeosporioides. The Δcgabcf2 mutant did not form the appressoria, lost the capability to infect apple and failed to form lesions on the wounded leaves and fruits...
June 20, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28634113/vitamin-d3-supplementation-attenuates-the-early-stage-of-mouse-hepatocarcinogenesis-promoted-by-hexachlorobenzene-fungicide
#3
Guilherme R Romualdo, Renata L Goto, Ana A H Fernandes, Bruno Cogliati, Luis F Barbisan
Hexachlorobezene (HCB), a fungicide widely distributed in the environment, promotes the development of hepatocellular preneoplastic lesions (PNL) and tumors in rodents. In contrast, vitamin D3 (VD3) supplementation presents a potential role for the prevention/treatment of chronic liver diseases. Thus, we investigated whether VD3 supplementation attenuates the early stage of HCB-promoted hepatocarcinogenesis. Female Balb/C mice were injected a single dose of diethylnitrosamine (DEN, 50 mg/kg) at postnatal day 15...
June 17, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28631903/-solitary-stones-of-the-lower-renal-calyx-how-to-treat
#4
A G Martov, D V Ergakov, A S Andronov, S V Dutov, R A Takhaev, Z I Kil'chukov, S A Moskalenko
INTRODUCTION: The choice of treatment for the stones of the lower renal calyx is one of the challenging issues of modern urology. The aim of this retrospective and prospective study was to investigate the clinical effectiveness and safety of 3 modern minimally invasive techniques for treating renal stones: percutaneous (PNL) and transurethral (TNL) nephrolithotripsy and extracorporeal shock wave lithotripsy (ESWL) in patients with solitary lower calyx stones sized from 10 to 15 mm. MATERIALS AND METHODS: The study included 136 patients with symptomatic stones of the lower calyces, who underwent ESWL, PNL and TNL from November 2010 to the present day...
June 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28613206/-evolution-from-percutaneous-nephrolithotomy-to-mini-pcnl-in-supine-position-on-the-treatment-of-complex-renal-calculi-feasibility-study
#5
Fernando Ramón de Fata-Chillón, Helena Gimbernat-Díaz, Cristina Redondo-Redondo, Elisa Meilán-Hernández, Erika Mateo-Martínez
OBJECTIVES: Mini-PCNL is a potentially less invasive technique than standard percutaneous nephrolithotomy (PCNL). We present our experience and results comparing both approaches in large burden complex renal calculi. METHODS: Prospective non randomized study comparing PCNL (24/26F nephroscope; Group A) and Mini-PCNL (15/18F; Group B) perioperative and postoperative results, in 40 (20 each group) consecutive patients between 2013 and 2014. We analyze demographic data, hemoglobin drop, urine culture, stone characteristics, operative time, puncture, number and size of the tract, disintegration energy sources, nephrostomy placement, hospital stay, stone free rate and Clavien-Dindo complications...
June 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28567327/robot-assisted-laparoscopic-management-of-caliceal-diverticular%C3%A2-calculi
#6
Anneleen Verbrugghe, Loïc Gaillandre, Damien Mouton, Franck Deschildre, Philippe Koenig, Charles Ballereau, Pierre Colin
Standard treatment modalities of caliceal diverticular calculi range from extracorporal shockwave lithotripsy (SWL) over retrograde intrarenal surgery (RIRS), percutaneous nephrolithotomy (PNL) and laparoscopic stone removal. A 55-year-old woman presented with a history of pyelonephritis based on a caliceal diverticular calculus. Due to the narrow infundibulum and anterior location, a robot-assisted laparoscopic calicotomy with extraction of the calculi and fulguration of the diverticulum was performed, with no specific perioperative problems and good stone-free results...
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28560507/comparison-of-croes-s-t-o-n-e-and-guy-s-scoring-systems-for-the-prediction-of-stone-free-status-and-complication-rates-following-percutaneous-nephrolithotomy-in-patients-with-chronic-kidney-disease
#7
Fatih Yanaral, Faruk Ozgor, Metin Savun, Murat Sahan, Omer Sarilar, Murat Binbay
PURPOSE: To evaluate and compare the accuracy of S.T.O.N.E, Clinical Research Office of the Endourological Society (CROES), and Guy's stone score in patients with chronic kidney disease (CKD) following percutaneous nephrolithotomy (PNL). METHODS: The charts of patients who had undergone a prone percutaneous nephrolithotomy from June 2006 to June 2016 were retrospectively analyzed. Patients accepted as stage 3 and higher according to chronic kidney disease epidemiology collaboration formula, were enrolled into the study...
May 30, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28544506/photocatalytic-nanosheet-lithography-a-new-concept-for-photolithography-based-on-organically-modified-photoactive-2d-nanosheets
#8
Pirmin Ganter, Bettina Valeska Lotsch
Harvesting the properties of nanosheets is not only crucial from a fundamental perspective, but also for the development of novel functional devices based on 2D nanosheets. Here, we demonstrate the processing of organically modified TBAxH1-xCa2Nb3O10 nanosheets into photonic thin films and study their colorimetric sensing properties in response to various aqueous and organic solvent vapors. Building on the enhanced solvent accessibility of TBA-containing nanosheets and their photocatalytic activity under UV irradiation, we develop a new concept for photocatalytic lithography using TBAxH1-xCa2Nb3O10 nanosheets as a negative photoresist to obtain high-fidelity micron-scale patterns of robust inorganic nanosheets...
May 24, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28537701/effects-of-body-mass-index-on-the-outcomes-of-percutaneous-nephrolithotomy
#9
Cemal Selcuk Isoglu, Tufan Suelozgen, Hayal Boyacioglu, Gokhan Koc
OBJECTIVE: To examine the the effect of body mass index (BMI) on PNL results and complications with a large number of patients. MATERIALS AND METHODS: A total of 958 patients were included in the study, who underwent percutaneous nephrolithotomy in our clinic between 2008 and 2015. Patients were divided into 2 groups according to their body mass index. Patients with a BMI < 30 kg/m2 were classified as group 1 (n:676) and patients with a BMI ≥ 30 kg/m2 were classified as group 2 (n:282)...
May 23, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28523365/outcome-from-5-year-live-surgical-demonstrations-in-urinary-stone-treatment-are-outcomes-compromised
#10
Jaap D Legemate, Stefano P Zanetti, Joyce Baard, Guido M Kamphuis, Emanuele Montanari, Olivier Traxer, Jean Jmch de la Rosette
PURPOSE: To compare intra- and post-operative outcomes of endourological live surgical demonstrations (LSDs) and routine surgical practice (RSP) for urinary stones. METHODS: Consecutive ureterorenoscopic (URS) and percutaneous (PNL) urinary stone procedures over a 5-year period were reviewed. Procedures were divided into LSDs and RSP. Differences between the groups were separately analysed for URS and PNL. Primary outcomes included intra- and post-operative complication rates and grades...
May 18, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28498511/enhanced-antitumor-effect-of-targeted-nanoliposomal-bleomycin
#11
Mohsen Chiani, Kayhan Azadmanesh, Mohammad Ali Shokrgozar, Mohammad Reza Mehrabi, Azim Akbarzadeh, Dariush Norouzian
Folate receptor (FR)-mediated drug delivery is a promising approach for active targeting of drugs to the FR-positive tumor cells. Bleomycin (BLM) is an antitumor antibiotic with poor therapeutic activity as a result of its limited diffusion into tumor cells. The aim of this study was to investigate whether FR-targeted PEGylated nanoliposomes (FPNL) can effectively deliver BLM to tumor cells and enhance its in vitro and in vivo efficacy. FPNL and PNL (non-targeted) were prepared by thin film hydration method, and their physiochemical properties, cellular uptake, tissue distribution and tumor inhibitory effects were investigated...
May 12, 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/28359409/surgical-management-of-urinary-stones-with-abnormal-kidney-anatomy
#12
Giray Ergin, Mustafa Kirac, Ali Unsal, Burak Kopru, Mustafa Yordam, Hasan Biri
In spite of the fact that urologic surgical techniques used by urologists are becoming more and more minimally invasive and easier because of developing technologies, surgical approaches for the urinary stones in kidneys with abnormal anatomy are still confusing. The objective of this article is to determine the treatment options in these kidneys. For this purpose, between 2005 and 2015, we retrospectively evaluated patients operated for urolithiasis with various congenital renal anomalies in five referral urology clinics in our country...
April 2017: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/28357451/comparison-of-supine-and-prone-positions-for-percutaneous-nephrolithotomy-in-treatment-of-staghorn-stones
#13
Mehmet İlker Gökce, Arif Ibiş, Adem Sancı, Aykut Akıncı, Uygar Bağcı, Eylül Asya Ağaoğlu, Evren Süer, Ömer Gülpınar
INTRODUCTION: Percutaneous nephrolithotomy (PNL) is the primary treatment modality for management of staghorn stones. PNL in supine position has important advantages over prone positon. However, studies comparing prone and supine positions for PNL in staghorn stone patients have conflicting results, and the aim of the current study was to compare prone and supine positions for PNL in staghorn stone cases. PATIENTS AND METHODS: Data of patients underwent PNL for staghorn stones in supine or prone position by a single urologist were collected prospectively...
March 29, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28351191/acute-kidney-injury-after-percutaneous-nephrolithotomy-for-stones-in-solitary-kidneys
#14
Ahmed R El-Nahas, Diaa-Eldin Taha, Hussien M Ali, Ahmed M Elshal, Mohamed H Zahran, Nasr A El-Tabey, Ahmed M El-Assmy, Ahmed M Harraz, Hazem E Moawad, Mahmoud M Othman
OBJECTIVES: The aim of this study was to report the incidence, severity, outcome and risk factors of acute kidney injury (AKI) following percutaneous nephrolithotomy (PNL) in solitary kidneys. METHODS: The study included consecutive adult patients who underwent PNL for treatment of calculi in a solitary kidney between May 2012 and July 2015. Patients with congenital renal anomalies or with stages 4 and 5 chronic kidney disease (CKD) were excluded. Serum creatinine levels were measured the day before PNL, daily after PNL for 2-5 days and after 3 months...
March 29, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28255416/the-effects-of-previous-open-renal-stone-surgery-types-on-pnl-outcomes
#15
Faruk Ozgor, Onur Kucuktopcu, Burak Ucpinar, Omer Sarilar, Akif Erbin, Fatih Yanaral, Murat Sahan, Murat Binbay
INTRODUCTION: Our aim was to demonstrate the effect of insicion of renal parenchyma during open renal stone surgery (ORSS) on percutaneous nephrolithotomy (PNL) outcomes. METHODS: Patients with history of ORSS who underwent PNL operation between June 2005 and June 2015 were analyzed retrospectively. Patients were divided into two groups according to their type of previous ORSS. Patients who had a history of ORSS with parenchymal insicion, such as radial nephrotomies, anatrophic nephrolithotomy, lower pole resection, and partial nephrectomy, were included in Group 1...
July 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28253070/comparison-of-retrograde-intrarenal-surgery-and-percutaneous-nephrolithotomy-methods-in-treatment-of-upper-calyceal-stones-of-10-20%C3%A2-mm
#16
Volkan Selmi, Ismail Nalbant, Ufuk Ozturk, Can Tuygun, Hasan Nedim Goksel Goktug, Muhammed Abdurrahim Imamoglu
OBJECTIVE: To compare the success and complication rates and advantages and disadvantages of retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PNL) methods for the upper calyceal renal stones between 10 and 20 mm. MATERIALS AND METHODS: The files of 124 patients who had upper calyceal renal stones in diameter 10-20 mm were analyzed retrospectively. Sixty-one patients were randomized as Group 1 and 63 as Group 2. The parameters as success and complication rates, fluoroscopy and operation times, preoperative and postoperative hemogram (Hb) levels, and need of blood transfusion were saved and then groups compared...
March 2, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28248037/-prospects-for-using-biological-markers-in-various-types-of-urinary-stone-lithotripsy
#17
M M Kutluev, I L Pulin, A Ya Ryakhov, K S Mochalov, R R Farkhutdinov
AIM: To investigate the feasibility of using biological markers for determining the optimal timing to repeat lithotripsy of urinary stones. MATERIALS AND METHODS: This was a prospective, randomized, single-center cohort study of 100 patients randomized into 4 groups. Patients of group I (n=46), II (n=20), III (n=18) and IV (n=16) were used contact lithotripsy (URS), ESWL, PNL, combined lithotripsy. In all patients, before surgery and at 1, 7, 14, 20 days after lithotripsy, iron-induced urine chemiluminescence was measured to determine the level of reactive oxygen species (ROS) and concentration of medium-mass molecules (MMM) in urine...
December 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28247667/-ultraminipercutaneous-nephrolithotripsy-in-treating-kidney-stones
#18
A G Martov, S V Dutov, A S Andronov
INTRODUCTION: Percutaneous nephrolithotripsy (PNL) is the recommended method of surgical treatment of kidney stones of size greater than 2 cm. Trends in the development of modern urology have been steadily toward less traumatic method to treat nephrolithiasis - minimally invasive PNL. The present work aimed to explore of the possibilities of one of the modern variants of minimally invasive PNL - ultra-mini-PNL in treating nephrolithiasis. MATERIALS AND METHODS: The study included 60 patients (mean age 45...
April 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28247629/-percutaneous-nephrolithotripsy-in-patients-after-different-methods-of-urinary-diversion
#19
B G Guliev, E O Stetsik
The study presents the results of percutaneous nephrolithotripsy (PNL) in patients who underwent different methods of urinary diversion. MATERIALS AND METHODS: The study included the results of PNL in 16 patients (study group) with kidney stones who were subjected to different methods of urinary diversion. Earlier, 2 (12.5%) patients underwent bilateral ureterosigmoidostomy for bladder exstrophy, 12 (75%) experienced radical cystectomy with orthotopic ileocystoplasty and 2 (12.5%) - heterotopic cystoplasty...
August 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28237786/tract-sizes-in-miniaturized-percutaneous-nephrolithotomy-a-systematic-review-from-the-european-association-of-urology-urolithiasis-guidelines-panel
#20
Yasir Ruhayel, Abdulkadir Tepeler, Saeed Dabestani, Steven MacLennan, Aleš Petřík, Kemal Sarica, Christian Seitz, Andreas Skolarikos, Michael Straub, Christian Türk, Yuhong Yuan, Thomas Knoll
CONTEXT: Miniaturized instruments for percutaneous nephrolithotomy (PNL), utilizing tracts sized ≤22 Fr, have been developed in an effort to reduce the morbidity and increase the efficiency of stone removal compared with standard PNL (>22 Fr). OBJECTIVE: We systematically reviewed all available evidence on the efficacy and safety of miniaturized PNL for removing renal calculi. EVIDENCE ACQUISITION: The review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement...
February 22, 2017: European Urology
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