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Prediabetes

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https://www.readbyqxmd.com/read/28436739/prediabetes-exhibits-decreased-disposition-index-correlated-with-deterioration-of-glycemic-parameters-in-nonobese-japanese-subjects-a-cross-sectional-study-from-medical-examination
#1
Yasutaka Takeda, Yukihiro Fujita, Tsuyoshi Yanagimachi, Jun Honjo, Atsuko Abiko, Mahito Asai, Masakazu Haneda
BACKGROUND: Prediabetes, defined as impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), likely develops to type 2 diabetes mellitus (DM) and independently increases cardiovascular risk. We employed disposition index (DI), a new metabolic parameter indicating the pancreatic beta cell function adjusted for insulin resistance, and investigated whether it could be altered in Japanese population with prediabetes and associated with early glucose intolerance. METHODS: A total of 102 adults who underwent an oral glucose tolerance test at the medical screening were designated to normal glucose tolerance (NGT), IFG, IGT, and DM...
April 24, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28436293/food-insecurity-and-depression-among-adults-with-diabetes-results-from-the-national-health-and-nutrition-examination-survey-nhanes
#2
Joshua Montgomery, Juan Lu, Scott Ratliff, Briana Mezuk
Purpose While both food insecurity and depression have been linked to risk of type 2 diabetes, little is known about the relationship between food insecurity and depression among adults with diabetes. Research Design and Methods Cross-sectional analyses of the National Health and Nutrition Examination Survey (2011-2014), a nationally representative, population-based survey. Analytic sample was limited to adults aged ≥20 with diabetes determined by either fasting plasma glucose (≥126 mg/dL) or self-report (n = 1724) and adults age ≥20 with prediabetes determined by fasting plasma glucose (100-125 mg/dL) or self-report (n = 2004)...
April 1, 2017: Diabetes Educator
https://www.readbyqxmd.com/read/28435445/cardiometabolic-risk-factors-metabolic-syndrome-and-pre-diabetes-in-adolescents-in-the-sierra-region-of-ecuador
#3
Sharon L Casapulla, Cheryl A Howe, Gabriela Rosero Mora, Darlene Berryman, Mario J Grijalva, Edgar W Rojas, Masato Nakazawa, Jay H Shubrook
BACKGROUND: Excess weight (overweight and obesity) is the major modifiable risk factor for type 2 diabetes mellitus (T2DM) and other non-communicable diseases. However, excess weight may not be as predictive of diabetes risk as once thought. While excess weight and other obesity-related non-communicable diseases are of growing concern in low-middle income countries in Latin America, there is limited research on risk factors associated with T2DM in adolescents. This study investigated prevalence of overweight, obesity, prediabetes, diabetes and metabolic syndrome in adolescents in Ecuador...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28432876/effect-of-pistachio-consumption-on-the-modulation-of-urinary-gut-microbiota-related-metabolites-in-prediabetic-subjects
#4
Pablo Hernández-Alonso, Daniel Cañueto, Simona Giardina, Jordi Salas-Salvadó, Nicolau Cañellas, Xavier Correig, Mònica Bulló
The specific nutritional composition of nuts could affect different metabolic pathways involved in a broad range of metabolic diseases. We therefore investigated whether chronic consumption of pistachio nuts modifies the urine metabolome in prediabetic subjects. We designed a randomized crossover clinical trial in 39 prediabetic subjects. They consumed a pistachio-supplemented diet (PD, 50% carbohydrates, 33% fat, including 57 g/d of pistachios daily) and a control diet (CD, 55% carbohydrates, 30% fat) for 4 months each, separated by a 2-week wash-out...
April 12, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28432278/blood-glucose-concentration-and-risk-of-liver-cancer-systematic-review-and-meta-analysis-of-prospective-studies
#5
Hedong Han, Tianyi Zhang, Zhichao Jin, Honglei Guo, Xin Wei, Yuzhou Liu, Qi Chen, Jia He
The question of whether elevated blood glucose is a risk factor for liver cancer has been intensively studied, yet with inconsistent results. To explore the relationship between blood glucose concentration and risk of liver cancer, we conduct a meta-analysis of prospective studies. Literature search was comprehensively performed using database of PubMed, EMBASE and the Cochrane Library through October 2016. Random-effect models were used to combine the effect estimations. Eight articles containing ten studies with a total of 1975 liver cancer cases were included...
April 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28431967/family-centered-prevention-ameliorates-the-association-between-adverse-childhood-experiences-and-prediabetes-status-in-young-black-adults
#6
Gene H Brody, Tianyi Yu, Edith Chen, Gregory E Miller
Individuals exposed to adverse childhood experiences (ACEs) are vulnerable to various health problems later in life. This study was designed to determine whether participation in an efficacious program to enhance supportive parenting would ameliorate the association between ACEs and prediabetes status at age 25. Rural African American parents and their 11-year-old children (N=390) participated in the Strong African American Families (SAAF) program or a control condition. Each youth at age 25 provided a total ACEs score and a blood sample from which overnight fasting glucose was assayed...
April 18, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28430803/increase-in-serum-albumin-concentration-is-associated-with-prediabetes-development-and-progression-to-overt-diabetes-independently-of-metabolic-syndrome
#7
Ji Eun Jun, Seung-Eun Lee, You-Bin Lee, Jae Hwan Jee, Ji Cheol Bae, Sang-Man Jin, Kyu Yeon Hur, Moon-Kyu Lee, Jae Hyeon Kim
AIM: Serum albumin concentration is associated with both type 2 diabetes and metabolic syndrome (MetS). We sought to investigate whether baseline serum albumin and change in serum albumin could be independent risk factors for prediabetes in subjects without MetS. We further examined the effect of serum albumin on progression to overt diabetes in subjects who developed prediabetes. METHODS: Among 10,792 participants without diabetes and MetS who consecutively underwent yearly health check-ups over six years, 9,807 subjects without incident MetS were enrolled in this longitudinal retrospective study...
2017: PloS One
https://www.readbyqxmd.com/read/28429483/management-of-periodontal-health-in-children-pediatric-dentistry-and-periodontology-interface
#8
REVIEW
Bernadette K Drummond, Michael G Brosnan, Jonathan W Leichter
The oral health of children and adolescents mirrors their general health. Because oral health care is often delivered in isolation from general health care, oral signs and symptoms do not always alert practitioners to their significance beyond the mouth. An important example of this is the association of a higher risk of dental caries and periodontal disease in children and adolescents with overweight, obesity and prediabetic conditions. Oral-health practitioners need to consider the health conditions that their patients may have...
June 2017: Periodontology 2000
https://www.readbyqxmd.com/read/28428964/micrornas-mediated-regulation-of-skeletal-muscle-glut4-expression-and-translocation-in-insulin-resistance
#9
REVIEW
João Victor Esteves, Francisco Javier Enguita, Ubiratan Fabres Machado
The solute carrier family 2 facilitated glucose transporter member 4 (GLUT4) plays a key role in the insulin-induced glucose uptake by muscle and adipose tissues. In prediabetes and diabetes, GLUT4 expression/translocation has been detected as reduced, participating in mechanisms that impair glycemic control. Recently, a class of short endogenous noncoding RNAs named microRNAs (miRNAs) has been increasingly described as involved in the posttranscriptional epigenetic regulation of gene expression. The present review focuses on miRNAs potentially involved in the expression of GLUT4 expression, and proteins related to GLUT4 and translocation in skeletal muscle, seeking to correlate them with insulin resistance and diabetes...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28423969/process-evaluation-of-the-type-2-diabetes-mellitus-pulse-program-randomized-controlled-trial-recruitment-engagement-and-overall-satisfaction
#10
Elroy J Aguiar, Philip J Morgan, Clare E Collins, Ronald C Plotnikoff, Myles D Young, Robin Callister
BACKGROUND: Men are underrepresented in weight loss and type 2 diabetes mellitus (T2DM) prevention studies. PURPOSE: To determine the effectiveness of recruitment, and acceptability of the T2DM Prevention Using LifeStyle Education (PULSE) Program-a gender-targeted, self-administered intervention for men. METHODS: Men (18-65 years, high risk for T2DM) were randomized to intervention ( n = 53) or wait-list control groups ( n = 48). The 6-month PULSE Program intervention focused on weight loss, diet, and exercise for T2DM prevention...
April 1, 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/28422560/effect-of-physical-activity-intervention-in-prediabetes-a-systematic-review-with-meta-analysis
#11
Radhika Aditya Jadhav, Animesh Hazari, Ashma Monterio, Sampath Kuman, Arun G Maiya
BACKGROUND: Prediabetes is a strong risk factor for the development of Type2 Diabetes Mellitus (T2DM). Modification in lifestyle plays an important role to avoid the prognosis of T2DM and its complications in future. The aim of our study was to focus on the effectiveness of physical activity (PA) intervention program on different outcome measures in individuals with prediabetes. The effort of the present review was to contribute to the existing literature by strengthening the evidence pointing towards the positive impact of physical activity in individuals with prediabetes...
April 19, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28420816/coronary-atherosclerotic-plaque-characteristics-and-cardiovascular-risk-factors%C3%A3-insights-from-an-optical-coherence-tomography-study
#12
Roberta De Rosa, Mariuca Vasa-Nicotera, David M Leistner, Sophia M Reis, Claudia E Thome, Jes-Niels Boeckel, Stephan Fichtlscherer, Andreas M Zeiher
BACKGROUND: The association between cardiovascular risk factors (CVRF) and the risk of coronary events is widely acknowledged. Whether individual risk factors may be associated with distinct plaque characteristics is currently unclear. We investigated the relationship between CVRF and coronary plaque burden and phenotype.Methods and Results:We assessed coronary atherosclerotic plaque characteristics by optical coherence tomography in 67 patients with stable coronary artery disease undergoing coronary angiography...
April 14, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28420105/one-year-results-of-a-synthetic-intervention-model-for-the-primary-prevention-of-t2d-among-elderly-individuals-with-prediabetes-in-rural-china
#13
Zhao Hu, Lulu Qin, Huilan Xu
Objective: The objective of this study was to evaluate the effectiveness of a synthetic intervention model aimed at preventing type 2 diabetes and controlling plasma glucose, body weight and waist circumference in elderly individuals with prediabetes in rural China. Methods: We randomly assigned 434 (180 men and 254 women; mean age, 69 years; mean body mass index, 23.6 kg/m²) with prediabetes to either the intervention group or the control group. Each participant in the intervention group received synthetic intervention for 1 year...
April 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28418543/review-hba1c-has-low-accuracy-for-prediabetes-lifestyle-programs-and-metformin-reduce-progression-to-t2dm
#14
Dennis G Maki
No abstract text is available yet for this article.
April 18, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28414819/glycemic-markers-and-relation-with-arterial-stiffness-in-caucasian-subjects-of-the-mark-study
#15
MULTICENTER STUDY
Leticia Gomez-Sanchez, Luis Garcia-Ortiz, Maria C Patino-Alonso, Jose I Recio-Rodriguez, Natalia Feuerbach, Ruth Marti, Cristina Agudo-Conde, Emiliano Rodriguez-Sanchez, Jose A Maderuelo-Fernandez, Rafel Ramos, Manuel A Gomez-Marcos
BACKGROUND: Effect of prediabetes and normal glucose on arterial stiffness remains controversial. The primary aim of this study was to investigate the relationship of fasting plasma glucose (FPG), postprandial glucose (PG) and glycosylated haemoglobin (HbA1c) with brachial-ankle pulse wave velocity (baPWV) and cardio-ankle vascular index (CAVI) in Caucasian adults. The secondary aim was to analyse this relationship by glycaemic status. METHODS: Cross-sectional study...
2017: PloS One
https://www.readbyqxmd.com/read/28414072/resistance-training-is-associated-with-spontaneous-changes-in-aerobic-physical-activity-but-not-overall-diet-quality-in-adults-with-prediabetes
#16
Tanya M Halliday, Jyoti Savla, Elaina L Marinik, Valisa E Hedrick, Richard A Winett, Brenda M Davy
BACKGROUND: Aerobic exercise interventions have been shown to result in alterations to dietary intake and non-exercise physical activity (PA). To date, the ability for resistance training (RT) to influence other health-related behaviors has not been examined. This study aimed to determine if initiation and maintenance of RT is associated with spontaneous changes in dietary quality and non-RT PA in adults with prediabetes. METHODS: Overweight/obese adults (n=170, BMI=32...
April 14, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28412822/determinants-of-lifestyle-behavior-in-iranian-adults-with-prediabetes-applying-the-theory-of-planned-behavior
#17
Fatemeh Rahmati-Najarkolaei, Amir H Pakpour, Mohsen Saffari, Mahboobeh Sadat Hosseini, Fereshteh Hajizadeh, Hui Chen, Mir Saeed Yekaninejad
OBJECTIVE: Prediabetic condition can lead to development of type 2 diabetes, especially in individuals who do not adhere to a healthy lifestyle. The aim of the present study was to investigate the socio-cognitive factors using the Theory of Planned Behavior (TPB) that may be associated with the choice of lifestyle in prediabetic patients. METHODS: A prospective study with one-month follow up was designed to collect data from 350 individuals with prediabetic conditions...
April 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/28406338/increased-kallistatin-levels-in-patients-with-obesity-and-prediabetes-compared-to-normal-glucose-tolerance
#18
Antoaneta Gateva, Yavor Assyov, Tsvetelina Velikova, Zdravko Kamenov
PURPOSE: Kallistatin is a member of serine protease inhibitors (SERPIN) family, which has various functions such as regulation of cardiovascular function and blood vessels development. Its levels are elevated in patients with type 1 and type 2 diabetes with chronic diabetic complications. The aim of the present study was to compare serum kallistatin levels between obese subjects with prediabetes and with normal glucose tolerance. METHODS: In this study we included 80 subjects at mean age of 50...
May 2017: Endocrine Research
https://www.readbyqxmd.com/read/28402800/assessment-of-dysglycemia-risk-in-the-kitikmeot-region-of-nunavut-using-the-canrisk-tool
#19
Ying Jiang, Susan Rogers Van Katwyk, Yang Mao, Heather Orpana, Gina Argwal, Margaret de Groh, Monique Skinner, Robyn Clarke, Howard Morrison
INTRODUCTION: The Public Health Agency of Canada adapted a Finnish diabetes screening tool (FINDRISC) to create a tool (CANRISK) tailored to Canada's multi-ethnic population. CANRISK was developed using data collected in seven Canadian provinces. In an effort to extend the applicability of CANRISK to northern territorial populations, we completed a study with the mainly Inuit population in the Kitikmeot region of Nunavut. METHODS: We obtained CANRISK questionnaires, physical measures and blood samples from participants in five Nunavut communities in Kitikmeot...
April 2017: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/28396144/supplementation-of-diet-with-galacto-oligosaccharides-increases-bifidobacteria-but-not-insulin-sensitivity-in-obese-prediabetic-individuals
#20
Emanuel E Canfora, Christina M van der Beek, Gerben D A Hermes, Gijs H Goossens, Johan W E Jocken, Jens J Holst, Hans M van Eijk, Koen Venema, Hauke Smidt, Erwin G Zoetendal, Cornelis H C Dejong, Kaatje Lenaerts, Ellen E Blaak
BACKGROUND & AIMS: The gut microbiota affects host lipid and glucose metabolism, satiety, and chronic low-grade inflammation to contribute to obesity and type 2 diabetes. Fermentation end products, in particular the short-chain fatty acid (SCFA) acetate, are believed to be involved in these processes. We investigate the long-term effects of supplementation with galacto-oligosaccharides (GOS), an acetogenic fiber, on the composition of the human gut microbiota and human metabolism. METHODS: We performed a double-blinded, placebo-controlled, parallel intervention study of 44 overweight or obese (body mass index, 28-40 kg/m2) prediabetic men and women (ages, 45-70 years) from October 2014 through October 2015 in Maastricht, The Netherlands...
April 7, 2017: Gastroenterology
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