keyword
MENU ▼
Read by QxMD icon Read
search

Golden hour

keyword
https://www.readbyqxmd.com/read/29846962/breast-crawl-the-attractive-warmth-of-the-mammary-areola
#1
Vincenzo Zanardo
In her famous paper Gastric suction in healthy newborn infants - effects on circulation and developing feeding behavior, which was published in Acta Paediatrica Scandinavica in 1987, the Swedish midwife Ann-Marie Widström wrote that healthy newborn infants were able to find the maternal mammary gland by themselves and start nutritive sucking (1). The sequence was illustrated by amazing pictures and Widström et al described how the newborn infants exhibited several behavioural phases during "the first magical golden hour" before the mouth opened over the nipple and breastfeeding began...
May 30, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29844910/factors-associated-with-late-arrival-of-acute-stroke-patients-to-emergency-department-in-saudi-arabia
#2
Ali M Al Khathaami, Yasmeen O Mohammad, Fatimah S Alibrahim, Hoda A Jradi
Background: Tissue plasminogen activator within 4.5 h of onset is effective for acute ischemic stroke. However, only small proportion of patients is treated due to delayed presentation. We aimed to examine the factors associated with delays of stroke patients in Riyadh, Saudi Arabia. Methods: A cross-sectional survey was conducted at King Abdulaziz Medical City, Riyadh, Saudi Arabia, during a 6-month period. An interviewer administered structured questionnaire addressed to the acute stroke patients or their relatives was used to explore the factors associated with delayed arrival...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29787557/extending-the-golden-hour-for-zone-1-reboa-improved-survival-and-reperfusion-injury-with-intermittent-versus-continuous-reboa-in-a-porcine-severe-truncal-hemorrhage-model
#3
John Kuckelman, Morgan Barron, Donald Moe, Michael Derickson, Cody Phillips, Joseph Kononchik, Michael Lallemand, Shannon Marko, Matthew Eckert, Matthew J Martin
BACKGROUND: Non-compressible hemorrhage can be controlled using resuscitative endovascular occlusion of the aorta (REBOA). Prolonged ischemia limits REBOA application during Zone 1 deployment. Intermittent inflation/deflation may effectively mitigate this problem. METHODS: A lethal abdominal vascular injury was created in 28 swine. Animals were randomized to controls (n=7), 60min full REBOA (FR, n=5), time-based intermittent REBOA (iRT, n=7), and pressure-based REBOA (iRP, n=9)...
May 2, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29774899/smartphone-based-rapid-quantification-of-viable-bacteria-by-single-cell-microdroplet-turbidity-imaging
#4
Xiaonan Cui, Lihui Ren, Yufei Shan, Xixian Wang, Zhenlong Yang, Chunyu Li, Jian Xu, Bo Ma
Standard plate count (SPC) has been recognized as the golden standard for the quantification of viable bacteria. However, SPC usually takes one to several days to grow individual cells into a visible colony, which greatly hampers its application in rapid bacteria enumeration. Here we present a microdroplet turbidity imaging based digital standard plate count (dSPC) method to overcome this hurdle. Instead of cultivating on agar plates, bacteria are encapsulated in monodisperse microdroplets for single-cell cultivation...
May 18, 2018: Analyst
https://www.readbyqxmd.com/read/29773768/us-cuba-health-and-science-cooperation-they-persisted
#5
(no author information available yet)
The first truly universal society was the society of researchers. May the coming generation establish a political and economic society which will insure us against catastrophes. -Albert Einstein in Havana, December 19, 1930 Few may be aware of Einstein's 30 hours in Cuba, just as the world was plummeting into the Great Depression. He was received by the most illustrious academics of his day, leaving the entry above in the Golden Book of the Geographic Society of Cuba. He spoke before what was then the Academy of Medical, Physical and Natural Sciences of Havana-precursor of the Cuban Academy of Sciences...
April 2018: MEDICC Review
https://www.readbyqxmd.com/read/29767482/multicenter-clinical-trial-on-a-permanent-hair-dye-containing-paratoluenediamine
#6
Caterina Foti, Nicola Balato, Antonio Cristaudo, Cataldo Patruno, Paolo Pigatto, Marina Ambrifi, Tamara Bufano, Giovanni Damiani, Mariagrazia De Rocco, Marco Diani, Maddalena Napolitano, Paolo Romita
BACKGROUND: Adverse reactions to hair dyes are frequent and usually caused by sensitization to paraphenylenediamine (PPD). The aim of the study was to evaluate the tolerability of a PPD-free permanent hair dye (Shine On, BioNike, Milan, Italy) containing paratoluenediamine (PTD) in a group of subjects sensitized to PPD. METHODS: The trial, which carried out at four dermatology centers, included subjects sensitized to PPD that turned out negative to patch testing to PTD...
August 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29748030/pharmacies-versus-doctors-offices-for-adolescent-vaccination
#7
Parth D Shah, Macary W Marciniak, Shelley D Golden, Justin G Trogdon, Carol E Golin, Noel T Brewer
PURPOSE: We evaluated how parents' willingness to get their children HPV vaccine from pharmacists related to their perceptions of relative advantages of vaccination in pharmacies compared to doctors' offices. METHODS: Participants were a national sample of 1500 U.S. parents of adolescents ages 11-17 recruited in 2014-15. In an online survey, items informed by Diffusion of Innovation Theory assessed parents' perceptions of the relative advantages of HPV vaccine delivery in pharmacies and doctors' offices...
May 7, 2018: Vaccine
https://www.readbyqxmd.com/read/29704128/prompting-with-electronic-checklist-improves-clinician-performance-in-medical-emergencies-a-high-fidelity-simulation-study
#8
Ronaldo Sevilla-Berrios, John C O'Horo, Christopher N Schmickl, Aysen Erdogan, Xiaomei Chen, Lisbeth Y Garcia Arguello, Yue Dong, Oguz Kilickaya, Brain Pickering, Rahul Kashyap, Ognjen Gajic
BACKGROUND: Inefficient processes of care delivery during acute resuscitation can compromise the "Golden Hour," the time when quick interventions can rapidly determine the course of the patient's outcome. Checklists have been shown to be an effective tool for standardizing care models. We developed a novel electronic tool, the Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN) to facilitate standardized evaluation and treatment approach for acutely decompensating patients...
April 27, 2018: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29688743/serial-culture-is-critical-for-in-vitro-development-of-parthenogenetic-embryos-in-the-golden-syrian-hamster
#9
Guangbin Zhou, Hengxi Wei, Xinrong Wang, Min Yang, Thomas D Bunch, Irina A Polejaeva, Kenneth L White, Zhongde Wang, Qinggang Meng
Unlike oocytes of many other mammalian species, parthenogenetically activated hamster oocytes have not been reported to develop beyond the two-cell stage. This study investigated the in vitro development into blastocysts of parthenogenetic embryos of Golden Syrian hamsters. We observed that hamster oocytes could easily be artificially activated (AA) by treatment with ionomycin plus 6-dimethylaminopurine + cycloheximide + cytochalasin B as assessed by embryo cleavage in HECM-9 (63.15%) or HECM-10 (63.82%). None of the cleaved embryos developed beyond the two-cell stage when cultured in either of the two media...
June 2018: Cellular Reprogramming
https://www.readbyqxmd.com/read/29643063/evaluation-of-prexasertib-a-checkpoint-kinase-1-inhibitor-in-a-phase-ib-study-of-patients-with-squamous-cell-carcinoma
#10
David S Hong, Kathleen Moore, Manish Patel, Stefan C Grant, Howard A Burris, William N William, Suzanne Jones, Funda Meric-Bernstam, Jeffrey Infante, Lisa Golden, Wei Zhang, Ricardo Martinez, Sameera Wijayawardana, Richard Beckmann, Aimee Bence Lin, Cathy Eng, Johanna Bendell
Purpose: Prexasertib, a checkpoint kinase 1 inhibitor, demonstrated single-agent activity in patients with advanced squamous cell carcinoma (SCC) in the dose-escalation portion of a phase I study (NCT01115790). Monotherapy prexasertib was further evaluated in patients with advanced SCC. Experimental Design: Patients were given prexasertib 105 mg/m2 as a 1-hour infusion on day 1 of a 14-day cycle. Expansion cohorts were defined by tumor and treatment line. Safety, tolerability, efficacy, and exploratory biomarkers were analyzed...
April 11, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29624558/a-phase-1-pharmacokinetic-and-safety-study-of-extended-duration-high-dose-cefixime-for-cephalosporin-resistant-neisseria-gonorrhoeae-in-the-pharynx
#11
Lindley A Barbee, Seema U Nayak, Jeffrey L Blumer, Mary Ann O'Riordan, Wesley Gray, Jonathan M Zenilman, Matthew R Golden, J McLeod Griffiss
BACKGROUND: There are no fully oral recommended treatment regimens for gonorrhea. Inadequately treated pharyngeal gonococcal infections are a likely reservoir for transmission and development of antimicrobial resistance. We sought to determine an oral cefixime dosing regimen that would theoretically treat pharyngeal infections by gonococci with MICs 0.5μg/mL. METHODS: We conducted an open label, non-randomized, Phase I pharmacokinetic and safety study of cefixime in 25 healthy male and female volunteers divided into four dosing cohorts (Cohort A, 400 mg; Cohort B, 800 mg; Cohort C, 1200 mg; and Cohort D, 800 mg q8h x 3 doses [total dose 2400mg]) with a target serum concentration of ≥2...
April 5, 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29610867/golden-hour-great-lawn-central-park
#12
(no author information available yet)
No abstract text is available yet for this article.
April 1, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29527311/development-and-validation-of-a-prediction-model-for-insulin-associated-hypoglycemia-in-non-critically-ill-hospitalized-adults
#13
Nestoras Nicolas Mathioudakis, Estelle Everett, Shuvodra Routh, Peter J Pronovost, Hsin-Chieh Yeh, Sherita Hill Golden, Suchi Saria
Objective: To develop and validate a multivariable prediction model for insulin-associated hypoglycemia in non-critically ill hospitalized adults. Research design and methods: We collected pharmacologic, demographic, laboratory, and diagnostic data from 128 657 inpatient days in which at least 1 unit of subcutaneous insulin was administered in the absence of intravenous insulin, total parenteral nutrition, or insulin pump use (index days). These data were used to develop multivariable prediction models for biochemical and clinically significant hypoglycemia (blood glucose (BG) of ≤70 mg/dL and <54 mg/dL, respectively) occurring within 24 hours of the index day...
2018: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/29474335/the-golden-hours-of-icu-sedation-the-clock-is-ticking
#14
Yahya Shehabi
No abstract text is available yet for this article.
March 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29460672/effects-of-distance-and-rescue-time-to-medical-facilities-on-traffic-mortality-utilizing-gis
#15
Wei Hu, Qiao Dong, Baoshan Huang
Although supported by little scientific evidence, the concept of 'golden hour,' which claims that mortality for trauma patients rises significantly over rescue time, plays a vital role in the design of our current trauma system. Only the contrary results could be found by using Fatality Analysis Reporting System data from 2010 to 2012. The results of logistic regression showed that longer total time intervals were associated with lower traffic mortality, with an odds ratio (OR) of 0.993 per minute. Utilizing the closest facility solver in the Geographic Information System, the effect of 'reverse causation' and the difference between trauma centre and non-trauma centre on the time-mortality relationship were discussed...
February 20, 2018: International Journal of Injury Control and Safety Promotion
https://www.readbyqxmd.com/read/29455683/defining-ct-perfusion-thresholds-for-infarction-in-the-golden-hour-and-with-ultra-early-reperfusion
#16
Mohamed Najm, Fahad S Al-Ajlan, Mari E Boesen, Lisa Hur, Chi Kyung Kim, Enrico Fainardi, Michael D Hill, Andrew M Demchuk, Mayank Goyal, Ting Y Lee, Bijoy K Menon
In this brief report, computed tomography perfusion (CTP) thresholds predicting follow-up infarction in patients presenting 20 to 23 seconds and cerebral blood flow <5 to 7 ml/min-1/(100 g)-1 or relative cerebral blood flow <0.14 to 0.20 optimally predicted the final infarct. These thresholds are stricter than published thresholds.
February 19, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29449604/intravenous-synthetic-platelet-synthoplate-nanoconstructs-reduce-bleeding-and-improve-golden-hour-survival-in-a-porcine-model-of-traumatic-arterial-hemorrhage
#17
DaShawn A Hickman, Christa L Pawlowski, Andrew Shevitz, Norman F Luc, Ann Kim, Aditya Girish, Joyann Marks, Simi Ganjoo, Stephanie Huang, Edward Niedoba, Ujjal D S Sekhon, Michael Sun, Mitchell Dyer, Matthew D Neal, Vikram S Kashyap, Anirban Sen Gupta
Traumatic non-compressible hemorrhage is a leading cause of civilian and military mortality and its treatment requires massive transfusion of blood components, especially platelets. However, in austere civilian and battlefield locations, access to platelets is highly challenging due to limited supply and portability, high risk of bacterial contamination and short shelf-life. To resolve this, we have developed an I.V.-administrable 'synthetic platelet' nanoconstruct (SynthoPlate), that can mimic and amplify body's natural hemostatic mechanisms specifically at the bleeding site while maintaining systemic safety...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29440392/structure-function-and-mechanism-of-the-core-circadian-clock-in-cyanobacteria
#18
REVIEW
Jeffrey A Swan, Susan S Golden, Andy LiWang, Carrie L Partch
Circadian rhythms enable cells and organisms to coordinate their physiology with the cyclic environmental changes that come as a result of Earth's light/dark cycles. Cyanobacteria make use of a post-translational oscillator to maintain circadian rhythms, and this elegant system has become an important model for circadian timekeeping mechanisms. Composed of three proteins, the KaiABC system undergoes an oscillatory biochemical cycle that provides timing cues to achieve a 24-h molecular clock. Together with the input/output proteins SasA, CikA, and RpaA, these six gene products account for the timekeeping, entrainment, and output signaling functions in cyanobacterial circadian rhythms...
April 6, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29377268/elevated-donor-plasminogen-activator-inhibitor-1-levels-and-the-risk-of-primary-graft-dysfunction
#19
Barbara C S Hamilton, Gabriela R Dincheva, Hanjing Zhuo, Jeffrey A Golden, Marek Brzezinski, Jonathan P Singer, Michael A Matthay, Jasleen Kukreja
Primary graft dysfunction (PGD) following lung transplantation is associated with elevated recipient plasma levels of plasminogen activator inhibitor-1 (PAI-1) and the receptor for advanced glycation end products (RAGE). However, the significance of these biomarkers in the donor plasma is uncertain. We hypothesized that elevated donor plasma levels of PAI-1 and RAGE would be associated with recipient PGD. We carried out a prospective unmatched case-control study of double-lung transplant recipients between May 2014 and September 2015...
January 29, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29336762/r-a-cowley-the-golden-hour-the-momentary-pause-and-the-third-space
#20
David E Clark
R Adams Cowley (1917-1991), the Baltimore thoracic and trauma surgeon, was an outstanding politician and promoter of emergency medical services. His skills included the effective use of language, for example, identifying the critical time immediately after injury as a "golden hour," and describing shock as a "momentary pause in the act of death." Conversely, Cowley avoided the tendency of some contemporaries to justify massive crystalloid infusion by invoking a "third space." Cowley is often assumed to have originated the first two phrases, but, in fact, their histories go back at least to the 19th century and illustrate the development of surgical science...
December 1, 2017: American Surgeon
keyword
keyword
22617
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"