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https://www.readbyqxmd.com/read/28535277/sensory-impairments-and-cognitive-function-in-middle-aged-adults
#1
Carla R Schubert, Karen J Cruickshanks, Mary E Fischer, Yanjun Chen, Barbara E K Klein, Ronald Klein, A Alex Pinto
Background: Hearing, visual, and olfactory impairments have been associated with cognitive impairment in older adults but less is known about associations with cognitive function in middle-aged adults. Methods: Sensory and cognitive functions were measured on participants in the baseline examination (2005-2008) of the Beaver Dam Offspring Study. Cognitive function was measured with the Trail Making tests A (TMTA) and B (TMTB) and the Grooved Peg Board test. Pure-tone audiometry, Pelli-Robson letter charts, and the San Diego Odor Identification test were used to measure hearing, contrast sensitivity, and olfaction, respectively...
May 23, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28530519/does-a-one-size-fits-all-cost-sharing-approach-incentivize-appropriate-medication-use-a-roundtable-on-the-fairness-and-ethics-associated-with-variable-cost-sharing
#2
Jennifer S Graff, Chuck Shih, Thomas Barker, Gabriela Dieguez, Cheryl Larson, Helen Sherman, Robert W Dubois
BACKGROUND: Tiered formularies, in which patients pay copays or coinsurance out-of-pocket (OOP), are used to manage costs and encourage more efficient health care resource use. Formulary tiers are typically based on the cost of treatment rather than the medical appropriateness for the patient. Cost sharing may have unintended consequences on treatment adherence and health outcomes. Use of higher-cost, higher-tier medications can be due to a variety of factors, including unsuccessful treatment because of lack of efficacy or side effects, patient clinical or genetic characteristics, patient preferences to avoid potential side effects, or patient preferences based on the route of administration...
June 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28528207/interventions-to-increase-male-attendance-and-testing-for-sexually-transmitted-infections-at-publicly-funded-family-planning-clinics
#3
David Fine, Lee Warner, Sarah Salomon, David M Johnson
PURPOSE: We assessed the impact of staff, clinic, and community interventions on male and female family planning client visit volume and sexually transmitted infection testing at a multisite community-based health care agency. METHODS: Staff training, clinic environmental changes, in-reach/outreach, and efficiency assessments were implemented in two Family Health Center (San Diego, CA) family planning clinics during 2010-2012; five Family Health Center family planning programs were identified as comparison clinics...
May 17, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28527809/accuracy-of-genomic-predictions-in-gyr-bos-indicus-dairy-cattle
#4
S A Boison, A T H Utsunomiya, D J A Santos, H H R Neves, R Carvalheiro, G Mészáros, Y T Utsunomiya, A S do Carmo, R S Verneque, M A Machado, J C C Panetto, J F Garcia, J Sölkner, M V G B da Silva
Genomic selection may accelerate genetic progress in breeding programs of indicine breeds when compared with traditional selection methods. We present results of genomic predictions in Gyr (Bos indicus) dairy cattle of Brazil for milk yield (MY), fat yield (FY), protein yield (PY), and age at first calving using information from bulls and cows. Four different single nucleotide polymorphism (SNP) chips were studied. Additionally, the effect of the use of imputed data on genomic prediction accuracy was studied...
May 17, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28525822/the-interplay-between-diabetes-depression-and-affective-temperaments-a-structural-equation-model
#5
Martino Belvederi Murri, Sara Mamberto, Lucia Briatore, Chiara Mazzucchelli, Mario Amore, Renzo Cordera
BACKGROUND: Diabetes and depression are reciprocally linked, but few studies modeled their interplay considering the influence of affective temperaments (AT) and demographic factors. METHODS: Participants with type 1 and type 2 diabetes (T1DM and T2DM, n=279) recruited from Diabetes Units were assessed with the Beck Depression Inventory (BDI), Temperament Evaluation of Memphis, Pisa, Paris and San Diego-autoquestionnaire version (TEMPS-A), Morisky Medication Adherence Scale (MMAS), Diabetes Distress Scale (DDS) and Cumulative Illness Rating Scales (CIRS)...
May 11, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28523460/evaluation-of-the-effect-of-torsemide-on-warfarin-dosage-requirements
#6
Sophia Lai, Jeremiah D Momper, Felix K Yam
Background According to drug interaction databases, torsemide may potentiate the effects of warfarin. Evidence for this drug-drug interaction, however, is conflicting and the clinical significance is unknown. Objective The aim of this study is to evaluate the impact of torsemide initiation on warfarin dosage requirements. Setting This study was conducted at the Veterans Affairs Healthcare System in San Diego, California. Method A retrospective cohort study was conducted using Veterans Affairs data from patients who were converted from bumetanide to torsemide between March 2014 and July 2014...
May 18, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28520873/association-between-neurocognitive-decline-and-visual-field-variability-in-glaucoma
#7
Alberto Diniz-Filho, Lisa Delano-Wood, Fábio B Daga, Sebastião Cronemberger, Felipe A Medeiros
Importance: Visual field variability may impair detection of glaucoma progression over time. Despite the possible overlap between neurocognitive disorders and glaucoma in older individuals, no study has investigated the association between cognitive changes and visual field variability. Objective: To evaluate the association between global neurocognitive impairment and visual field variability in patients diagnosed as having glaucoma or glaucoma suspects. Design, Setting, and Participants: This prospective observational cohort study was conducted at the Visual Performance Laboratory, University of California, San Diego...
May 18, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28520484/fe-en-acci%C3%A3-n-promoting-physical-activity-among-churchgoing-latinas
#8
Elva M Arredondo, John P Elder, Jessica Haughton, Donald J Slymen, James F Sallis, Lilian G Perez, Natalicio Serrano, Maíra T Parra, Rodrigo Valdivia, Guadalupe X Ayala
OBJECTIVES: To evaluate the impact of a faith-based intervention to promote physical activity in Latinas. METHODS: We randomized 16 churches in San Diego County, California, to a physical activity intervention or cancer screening comparison condition (n = 436). The intervention followed an ecological framework and involved promotoras. We examined 12-month intervention effects, including accelerometer-based moderate-to-vigorous physical activity (MVPA; primary outcome) and secondary outcomes...
May 18, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28503372/endosymbiont-interference-and-microbial-diversity-of-the-pacific-coast-tick-dermacentor-occidentalis-in-san-diego-county-california
#9
Nikos Gurfield, Saran Grewal, Lynnie S Cua, Pedro J Torres, Scott T Kelley
The Pacific coast tick, Dermacentor occidentalis Marx, is found throughout California and can harbor agents that cause human diseases such as anaplasmosis, ehrlichiosis, tularemia, Rocky Mountain spotted fever and rickettsiosis 364D. Previous studies have demonstrated that nonpathogenic endosymbiotic bacteria can interfere with Rickettsia co-infections in other tick species. We hypothesized that within D. occidentalis ticks, interference may exist between different nonpathogenic endosymbiotic or nonendosymbiotic bacteria and Spotted Fever group Rickettsia (SFGR)...
2017: PeerJ
https://www.readbyqxmd.com/read/28498895/acute-illness-among-surfers-after-exposure-to-seawater-in-dry-and-wet-weather-conditions
#10
Benjamin F Arnold, Kenneth C Schiff, Ayse Ercumen, Jade Benjamin-Chung, Joshua A Steele, John F Griffith, Steven J Steinberg, Paul Smith, Charles D McGee, Richard Wilson, Chad Nelsen, Stephen B Weisberg, John M Colford
Rainstorms increase levels of fecal indicator bacteria in urban coastal waters, but it is unknown whether exposure to seawater after rainstorms increases rates of acute illness. Our objective was to provide the first estimates of rates of acute illness after seawater exposure during both dry- and wet-weather periods and to determine the relationship between levels of indicator bacteria and illness among surfers, a population with a high potential for exposure after rain. We enrolled 654 surfers in San Diego, California, and followed them longitudinally during the 2013-2014 and 2014-2015 winters (33,377 days of observation, 10,081 surf sessions)...
May 11, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28496268/effect-of-a-dedicated-pharmacy-student-summer-research-program-on-publication-rate
#11
Katharina Brandl, David Adler, Carolyn Kelly, Palmer Taylor, Brookie M Best
Objectives. This study investigated the impact of an optional 12-week summer research program on the publication outcomes and satisfaction with the required research projects of doctor of pharmacy (PharmD) students at the Skaggs School of Pharmacy and Pharmaceutical Sciences (SSPPS) at the University of California San Diego. Methods. PubMed and Google searches provided student publications, and satisfaction surveys submitted by students provided their perceptions of the research project value. Results. Of the studied cohort, the 130 students who fulfilled the requirement through the optional summer research program provided 61 full-text manuscripts and 113 abstracts...
April 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28492063/vaccination-with-killed-but-metabolically-active-e-coli-over-expressing-hemagglutinin-elicits-neutralizing-antibodies-to-h1n1-swine-origin-influenza-a-virus
#12
Pei-Feng Liu, Yanhan Wang, Yu-Tsueng Liu, Chun-Ming Huang
There is a need for a fast and simple method for vaccine production to keep up with the pace of a rapidly spreading virus in the early phases of the influenza pandemic. The use of whole viruses produced in chicken eggs or recombinant antigens purified from various expression systems has presented considerable challenges, especially with lengthy processing times. Here, we use the killed but metabolically active (KBMA) Escherichia coli (E. coli) to harbor the hemagglutinin (HA) of swine origin influenza A (H1N1) virus (S-OIV) San Diego/01/09 (SD/H1N1-S-OIV)...
February 2017: Journal of Nature and Science
https://www.readbyqxmd.com/read/28489967/associations-of-the-polymorphisms-in-dhrs4-serping1-and-apor-genes-with-postmortem-ph-in-berkshire-pigs
#13
Jung Hye Hwang, Sang Mi An, Seul Gi Kwon, Da Hye Park, Tae Wan Kim, Deok Gyung Kang, Go Eun Yu, Il-Suk Kim, Hwa Chun Park, Jeongim Ha, Chul Wook Kim
Postmortem pH is a main factor influencing the meat quality in pigs. This study investigated the association of postmortem pH with single-nucleotide polymorphisms (SNPs) in the fourth member of the short-chain dehydrogenase/reductase family (DHRS4), the first member of serpin peptidase inhibitor, clade G (complement inhibitor) (SERPING1), and the apolipoprotein R precursor (APOR) genes in Berkshire pigs. The study included 437 pigs, and genotyping was conducted using the GoldenGate Assay (Illumina, San Diego, CA, USA)...
May 10, 2017: Animal Biotechnology
https://www.readbyqxmd.com/read/28489777/affective-temperament-does-not-influence-satisfaction-after-total-knee-arthroplasty
#14
Mahmut Özdemir, İsmail Demirkale, Hakan Şeşen, Anil Taşkesen, Mustafa C Okkaoğlu, Murat Altay
BACKGROUND: Inherent temperament of the patient may predict the outcome of the surgical procedure. The purpose of this study was to ascertain whether negative affective temperament affects patient satisfaction and outcome measures. METHODS: This prospective study included 143 patients who underwent total knee arthroplasty for primary arthrosis. Preoperatively, the Memphis, Pisa, Paris and San Diego-Auto questionnaire was used to define the temperament of the patient...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28488087/comparison-of-three-popular-methods-for-recruiting-young-persons-who-inject-drugs-for-interventional-studies
#15
Melissa G Collier, Richard S Garfein, Jazmine Cuevas-Mota, Eyasu H Teshale
Persons who inject drugs (PWID) are at risk for adverse health outcomes as a result of their drug use, and the resulting social stigma makes this a difficult population to reach for interventions aimed at reducing morbidity and mortality. During our study of adult PWID aged ≤40 years living in San Diego during 2009 and 2010, we compared three different sampling methods: respondent-driven sampling (RDS), venue-based sampling at one syringe exchange program (SEP), and street-based outreach. We compared demographic, socioeconomic, health, and behavioral factors and tested participants for HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV) and compared across the three methods...
May 9, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28483085/biopsychosocial-predictors-of-interferon-related-depression-in-patients-with-hepatitis-c
#16
Martino Belvederi Murri, Angela Chiara Cecere, Mattia Masotti, Giorgio Sammito, Alessandra la Marca, Giuseppe Valerio Torres, Iris Bonfitto, Edwige Cuozzo, Luca Rossi, Gaetano Serviddio, Rosanna Villani, Antonino Picciotto, Antonello Bellomo, Mario Amore
OBJECTIVES: The aim of this study is to examine the role of different bio-psycho-social risk factors for the onset of depression among patients with Hepatitis C (HCV) treated with Interferon alpha (IFN). MATERIAL AND METHODS: Patients with HCV were recruited and assessed prospectively at baseline and after 4, 8, and 24 weeks since the start of IFN treatment. Assessments included the Hamilton Depression and Anxiety Rating Scales (HAM-D and HAM-A), Toronto Alexithymia Scale, Temperament Evaluation of the Memphis, Pisa, Paris and San Diego, 110 item version (TEMPS-A), Young Mania Rating Scale and other assessment tools...
April 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28472420/determination-of-vh-family-usage-in-b-cell-malignancies-via-the-biomed-2-igh-pcr-clonality-assay
#17
Thomas J McDonald, Linus Kuo, Frank C Kuo
Objectives: To determine whether V H family usage in B-cell lymphoproliferative disorders can be deduced from polymerase chain reaction (PCR) product-length information obtained through the BIOMED-2 (Invivoscribe, San Diego, CA) clonality assay. Methods: We develop an algorithm that uses the sizing information of the BIOMED-2 immunoglobulin heavy chain (IGH) clonality assay to deduce V H family usage. PCR with family-specific primers on 51 clinical samples containing 54 rearranged alleles were used to validate the algorithm...
May 3, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28468147/a-surgical-technique-for-management-of-the-metopic-suture-in-syndromic-craniosynostosis
#18
Jose Rolando Prada-Madrid, Lina Patricia Franco-Chaparro, Miguel Garcia-Wenninger, Tatiana Palomino-Consuegra, Nora Stanford, Diego Alejandro Castañeda-Hernández
OBJECTIVES: The objective is to describe a new surgical procedure developed in the San Jose Pediatric University Hospital for the management of syndromic synostosis of the metopic suture in a patient clinically diagnosed with Saethre-Chotzen syndrome. METHODS: The diagnosis of Saethre-Chotzen syndrome, bilateral coronal sutures, and metopic suture synostoses was made through photographic, anthropometric, exophthalmometric, and computed tomography analysis. The keel-like frontal bone deformity was corrected following resection using a fusiform osteotomy, remodelling was obtained by milling the edges, and the bony fragments were repositioned and fixed on the posterior wall of the frontal bone...
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28467955/the-impact-of-currently-recommended-antihypertensive-therapy-on-depression-and-other-psychometric-parameters-preliminary-communication
#19
Beata Korosi, Andrea Laszlo, Adam Tabak, Dora Batta, Lilla Lenart, Andrea Fekete, Daniel Eorsi, Orsolya Cseprekal, Andras Tisler, Zsofia Nemcsik-Bencze, Xenia Gonda, Zoltan Rihmer, Janos Nemcsik
AIMS: Current evidence on the psychological effects of antihypertensive medications is controversial. The aim of this study was to evaluate the effect of current antihypertensive medication on different psychometric parameters and on serum brain-derived neurotrophic factor (BDNF) level. METHODS: Psychometric, haemodynamic, arterial stiffness and laboratory parameters were evaluated before and 3 months after the initiation of antihypertensive medication in untreated hypertensive patients (HT, n=31), and once in healthy controls (CONT, n=22)...
March 2017: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/28463449/school-and-neighborhood-predictors-of-physical-fitness-in-elementary-school-students
#20
David Kahan, Thomas L McKenzie
BACKGROUND: We assessed the associations of 5 school and 7 neighborhood variables with fifth-grade students achieving Healthy Fitness Zone (HFZ) or Needs Improvement-Health Risk (NI-HR) on aerobic capacity (AC) and body composition (BC) physical fitness components of the state-mandated FITNESSGRAM(®) physical fitness test. METHODS: Data for outcome (physical fitness) and predictor (school and neighborhood) variables were extracted from various databases (eg, Data Quest, Walk Score(®) ) for 160 schools located in San Diego, California...
June 2017: Journal of School Health
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