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https://www.readbyqxmd.com/read/28749270/health-survey-including-selected-blood-parameters-in-the-african-slender-snouted-crocodile-mecistops-cataphractus-at-the-abidjan-zoo-in-c%C3%A3-te-d-ivoire
#1
Carol Bradford, Matt Eschenbrenner
The Zoo National d'Abidjan (Abidjan Zoo) in Côte d'Ivoire, West Africa, holds the world's largest captive population of African slender-snouted crocodiles (Mecistops cataphractus, formerly Crocodylus cataphractus), at 36 adults, 16 yearlings, and 23 hatchlings. Twelve yearling and 12 adult slender-snouted crocodiles at the Abidjan Zoo were restrained for physical exam, body condition scoring, and venipuncture in September 2015. Blood samples collected from the supravertebral venous sinus were analyzed using a handheld blood analyzer (Abaxis® I-stat, Abaxis, Inc...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28745578/cost-effectiveness-of-g5-mobile-continuous-glucose-monitoring-cgm-device-compared-with-self-monitoring-of-blood-glucose-smbg-alone-for-people-with-type-1-diabetes-from-the-canadian-societal-perspective
#2
Shraddha Chaugule, Claudia Graham
AIMS: To evaluate the cost-effectiveness of real-time continuous glucose monitoring (CGM) compared to self-monitoring of blood glucose (SMBG) alone in people with type 1 diabetes (T1DM) using multiple daily injections (MDI) from the Canadian societal perspective. METHODS: The IMS CORE Diabetes Model (v.9.0) was used to assess the long-term (50 years) cost-effectiveness of real-time CGM (G5 Mobile CGM System; Dexcom, Inc., San Diego, CA) compared with SMBG alone for a cohort of adults with poorly-controlled T1DM...
July 26, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28745523/affective-temperaments-mood-and-insomnia-symptoms-in-a-non-clinical-sample
#3
Włodzimierz Oniszczenko, Marcin Rzeszutek, Ewa Stanisławiak
OBJECTIVE: The aim of the study was to understand the relationship between affective temperaments and insomnia symptoms and to examine mood state as a mediator in this relationship. PARTICIPANTS: The sample consisted of 659 adults (428 women and 231 men), aged between 18-77 years old, derived from a nonclinical population. METHODS: Affective temperaments were assessed using the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Autoquestionnaire (TEMPS-A)...
July 26, 2017: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/28742818/first-identification-of-a-recombinant-form-of-hepatitis-c-virus-in-austrian-patients-by-full-genome-next-generation-sequencing
#4
Evelyn Stelzl, Bernhard Haas, Bernd Bauer, Sherry Zhang, Ellen H Fiss, Grantland Hillman, Aaron T Hamilton, Rochak Mehta, Marintha L Heil, Ed G Marins, Brigitte I Santner, Harald H Kessler
Hepatitis C virus (HCV) intergenotypic recombinant forms have been reported for various HCV genotypes/subtypes in several countries worldwide. In a recent study, four patients living in Austria had been identified to be possibly infected with a recombinant HCV strain. To clarify results and determine the point of recombination, full-genome next-generation sequencing using the Illumina MiSeq v2 300 cycle kit (Illumina, San Diego, CA, USA) was performed in the present study. Samples of all of the patients contained the recombinant HCV strain 2k/1b...
2017: PloS One
https://www.readbyqxmd.com/read/28742395/highlights-from-the-biennial-international-congress-on-schizophrenia-research-icosr-march-24-march-28-2017
#5
Hakon Heimer
The 2017 International Congress on Schizophrenia Research, held in San Diego, California (March 24-28, 2017), attracted over 900 attendees from 34 countries. With the gracious assistance of Congress president James Meador-Woodruff, we bring you the following reports on the prospects for new drugs to treat schizophrenia.
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28739196/developing-optimized-treatment-plans-for-patients-with-dyslipidemia-in-the-era-of-pcsk9-inhibitor-therapeutics
#6
James A Underberg, Michael J Blaha, Elizabeth J Jackson Msn, Peter H Jones
This educational content was derived from live, satellite symposium at the American College of Physicians (ACP) Internal Medicine Meeting 2017 in San Diego, California (online at http://courses.elseviercme.com/acp/702e). This activity will focus on optimized treatment plans for patients with dyslipidemia in the era of PCSK9 inhibitor therapeutics. LDL-C has been identified as an important therapeutic target to prevent the progression of atherosclerotic disease, however only 1 out of every 3 adults with high LDL-C has the condition under control...
July 21, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28737994/impact-of-a-patient-support-program-on-patient-adherence-to-adalimumab-and-direct-medical-costs-in-crohn-s-disease-ulcerative-colitis-rheumatoid-arthritis-psoriasis-psoriatic-arthritis-and-ankylosing-spondylitis
#7
David T Rubin, Manish Mittal, Matthew Davis, Scott Johnson, Jingdong Chao, Martha Skup
BACKGROUND: AbbVie provides a free-to-patient patient support program (PSP) to assist adalimumab-treated patients with medication costs, nurse support, injection training, pen disposal, and medication reminders. The impact of these services on patient adherence to adalimumab and direct medical costs associated with autoimmune disease has not been assessed. OBJECTIVE: To quantify the relationship between participation in a PSP and outcomes (adalimumab adherence, persistence, and direct medical costs) in patients initiating adalimumab treatment...
August 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28729408/femoral-artery-atherosclerosis-is-associated-with-physical-function-across-the-spectrum-of-the-ankle-brachial-index-the-san-diego-population-study
#8
Christina L Wassel, Alicia M Ellis, Natalie C Suder, Emma Barinas-Mitchell, Dena E Rifkin, Nketi I Forbang, Julie O Denenberg, Antoinette M Marasco, Belinda J McQuaide, Nancy S Jenny, Matthew A Allison, Joachim H Ix, Michael H Criqui
BACKGROUND: The ankle-brachial index (ABI) is inadequate to detect early-stage atherosclerotic disease, when interventions to prevent functional decline may be the most effective. We determined associations of femoral artery atherosclerosis with physical functioning, across the spectrum of the ABI, and within the normal ABI range. METHODS AND RESULTS: In 2007-2011, 1103 multiethnic men and women participated in the San Diego Population Study, and completed all components of the summary performance score...
July 20, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28728633/drinking-status-between-ages-50-and-55-for-men-from-the-san-diego-prospective-study-who-developed-dsm-iv-alcohol-abuse-or-dependence-in-prior-follow-ups
#9
Priscila Dib Gonçalves, Marc A Schuckit, Tom L Smith
OBJECTIVE: Although alcohol use disorders (AUDs) are prevalent among older individuals, few studies have examined the course and predictors of AUDs from their onset into the person's 50s. This study describes the AUD course from ages 50 to 55 in participants who developed AUDs according to criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), during the San Diego Prospective Study (SDPS). METHOD: Among the 397 university students in the SDPS who were followed about every 5 years from age 20 (before AUD onset), 165 developed AUDs, 156 of whom were interviewed at age 55...
July 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28727669/differential-pulmonary-rehabilitation-outcomes-in-patients-with-and-without-copd-role-of-gender
#10
Lam-Phuong Nguyen, Emily Beck, Katherine Cayetano, Chin-Shang Li, Kimberly Hardin
PURPOSE: Individuals with all forms of pulmonary disease are referred for pulmonary rehabilitation. This study examines pulmonary rehabilitation outcomes between individuals with chronic obstructive lung disease (COPD) and non-COPD disease and the impact of gender. METHODS: This is a retrospective study at a tertiary center. The primary endpoint was the difference in 6-min walk test distance. Secondary measurements included treadmill and NuStep minutes; biceps curls and front arm raises load; quality of life measured by the St George's Respiratory Questionnaire; and University of California San Diego-Shortness of Breath Questionnaire (UCSD-SOBQ) scores...
July 19, 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28725275/ash-meeting-2016-developments-in-hemostaseology
#11
REVIEW
Clemens Feistritzer, Birgit Mosheimer
During the annual meeting of the American Society of Hematology (ASH) in San Diego/California, novel developments in the field of hemostaseology were presented. Alternative treatment strategies besides factor replacement were discussed for patients with hemophilia. One of the highlights of the meeting in this year's plenary session was the presentation of successful adeno-associated virus mediated gene transfer in patients with hemophilia B leading to sustained elevation of factor IX:C (FIX:c). Other alternative treatment approaches in patients with hemophilia A may include bispecific antibodies mimicking factor VIIIa (FVIIIa) activity or disrupting anticoagulant proteins...
2017: Memo
https://www.readbyqxmd.com/read/28720079/implementation-effectiveness-trial-of-an-ecological-intervention-for-physical-activity-in-ethnically-diverse-low-income-senior-centers
#12
Porchia Rich, Gregory A Aarons, Michelle Takemoto, Veronica Cardenas, Katie Crist, Khalisa Bolling, Brittany Lewars, Cynthia Castro Sweet, Loki Natarajan, Yuyan Shi, Kelsie M Full, Eileen Johnson, Dori E Rosenberg, Melicia Whitt-Glover, Bess Marcus, Jacqueline Kerr
BACKGROUND: As the US population ages, there is an increasing need for evidence based, peer-led physical activity programs, particularly in ethnically diverse, low income senior centers where access is limited. METHODS/DESIGN: The Peer Empowerment Program 4 Physical Activity' (PEP4PA) is a hybrid Type II implementation-effectiveness trial that is a peer-led physical activity (PA) intervention based on the ecological model of behavior change. The initial phase is a cluster randomized control trial randomized to either a peer-led PA intervention or usual center programming...
July 18, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28718202/patterns-of-mortality-in-a-montane-mixed-conifer-forest-in-san-diego-county-california
#13
Mary Pyott Freeman, Douglas A Stow, Li An
We examine spatial patterns of conifer tree mortality and their changes over time for the montane mixed-conifer forests of San Diego County. These forest areas have recently experienced extensive tree mortality due to multiple factors. A spatial contextual image processing approach was utilized with high spatial resolution digital airborne imagery to map dead trees for the years 1997, 2000, 2002, and 2005 for three study areas: Palomar, Volcan, and Laguna mountains. Plot-based fieldwork was conducted to further assess mortality patterns...
July 17, 2017: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/28716579/urinary-nnal-in-hookah-smokers-and-non-smokers-after-attending-a-hookah-social-event-in-a-hookah-lounge-or-a-private-home
#14
Nada O F Kassem, Noura O Kassem, Sandy Liles, Sheila R Jackson, Dale A Chatfield, Peyton Jacob, Neal L Benowitz, Melbourne F Hovell
Tobacco smoking and exposure to tobacco secondhand smoke (SHS) can cause lung cancer. We determined uptake of NNK (4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone), a tobacco specific potent pulmonary carcinogen, in hookah smokers and non-smokers exposed to hookah tobacco SHS. We analyzed data from a community-based convenience sample of 201 of adult (aged ≥18 years) exclusive hookah smokers (n = 99) and non-smokers (n = 102) residing in San Diego County, California. Participants spent an average of three consecutive hours indoors, in hookah lounges or private homes, where hookah tobacco was smoked exclusively...
July 14, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28713548/2017-iscb-accomplishment-by-a-senior-scientist-award-pavel-pevzner
#15
EDITORIAL
Christiana N Fogg, Diane E Kovats, Bonnie Berger
The International Society for Computational Biology ( ISCB) recognizes an established scientist each year with the Accomplishment by a Senior Scientist Award for significant contributions he or she has made to the field. This award honors scientists who have contributed to the advancement of computational biology and bioinformatics through their research, service, and education work. Pavel Pevzner, PhD, Ronald R. Taylor Professor of Computer Science and Director of the NIH Center for Computational Mass Spectrometry at University of California, San Diego, has been selected as the winner of the 2017 Accomplishment by a Senior Scientist Award...
2017: F1000Research
https://www.readbyqxmd.com/read/28711872/cell-scientist-to-watch-kevin-corbett
#16
(no author information available yet)
Kevin Corbett graduated in biology and biochemistry from the University of Virginia. He then went to the University of California, Berkeley, to work on the structure and function of DNA topoisomerases in bacteria and archaea for his PhD with James Berger. In 2005, he moved to the laboratory of Stephen Harrison at Harvard Medical School for his postdoctoral work on kinetochore structure and function, particularly the yeast monopolin complex, which promotes proper chromosome segregation in the first meiotic division...
July 15, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28709118/combat-exposure-and-pain-in-male-and-female-afghanistan-and-iraq-veterans-the-role-of-mediators-and-moderators
#17
Melissa M Buttner, Kathryn M Godfrey, Elizabeth Floto, James Pittman, Laurie Lindamer, Niloofar Afari
Veterans experience physical health problems associated with disability and poor quality of life following combat exposure (CE). Understanding the CE-physical health relationship, specifically pain intensity and somatic pain, may inform etiological models and interventions. This study examined the CE-pain relationship, associated mediators, and gender as a moderator. 2381 veterans at the VA San Diego Healthcare System completed paper or electronic self-report measures of pain intensity and somatic pain. Analyses examined associations of pain with CE and posttraumatic stress disorder (PTSD), depression, and resilience as mediators of the CE-pain association...
July 3, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28708003/arntl-clock-and-per3-polymorphisms-links-with-chronotype-and-affective-dimensions
#18
Konrad S Jankowski, Monika Dmitrzak-Weglarz
Recently, seven single nucleotide polymorphisms (SNPs) of ARNTL, TIM and PER3 genes were found associated with affective temperaments in bipolar disorder patients. This study aimed to test whether a) the same associations appear in a non-clinical sample; b) the SNPs are related to other affective dimensions; c) the SNPs underpin the associations between chronotype and affective temperaments/dimensions. Three hundred thirty-eight university students completed the Temperament Scale of Memphis, Pisa, Paris and San Diego Auto-questionnaire, the Centre for Epidemiological Studies Depression Scale, the Perceived Stress Scale, the General Health Questionnaire, the Seasonal Pattern Assessment Questionnaire and the Composite Scale of Morningness...
July 14, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28702851/sexual-partner-concurrency-among-partners-reported-by-msm-with-recent-hiv-infection
#19
Heather A Pines, Maile Y Karris, Susan J Little
We examined concurrency among sexual partners reported by men who have sex with men (MSM) with recent (acute or early) HIV infection in San Diego, California (2002-2015). Partners overlapping in time in the past 3 months were considered concurrent. Logistic generalized linear mixed models were used to identify factors associated with concurrency at the partner-level. 56% (388/699) of partners were concurrent to ≥1 other partner. The odds of concurrency were higher among partners >10 years younger than the participant (vs...
July 12, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28696779/the-impact-of-retail-beverage-service-training-and-social-host-laws-on-adolescents-dui-rates-in-san-diego-co-california
#20
Michael Scherer, Eduardo Romano, Susan Caldwell, Eileen Taylor
INTRODUCTION: Driving under the influence (DUI) citations are still a serious concern among drivers aged 16-20 years and have been shown to be related to increased risk of fatal and non-fatal crashes. A battery of laws and policies has been enacted to address this concern. While numerous studies have evaluated these policies, there is still a need for comprehensive policy evaluations that take into account a variety of contextual factors. Previous effort by this research team examined the impact of 20 minimum legal drinking age (MLDA)-21 laws in the state of California, as they impacted alcohol-related crash rates among drivers under 21 years of age while at the same time accounting for alcohol and gas taxes, unemployment rates, sex distribution among drivers, and sobriety checkpoints...
July 11, 2017: Traffic Injury Prevention
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