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Health promotion; health and development

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https://www.readbyqxmd.com/read/29331678/microrna-320-enhances-radiosensitivity-of-glioma-through-down-regulation-of-sirtuin-type-1-by-directly-targeting-forkhead-box-protein-m1
#1
Tengfei Li, Ji Ma, Xinwei Han, Yongxu Jia, Huifeng Yuan, Shaofeng Shui, Dong Guo
Glioma is the most common cancer in human brain system and seriously threatens human health. miRNA-320 has been demonstrated to be closely correlated with the development of glioma. However, its effect and molecular mechanism underlying radioresistance have not been fully elucidated in glioma. Here, RT-qPCR assay was used to assess the expressions of miR-320 and forkhead box protein M1 (FoxM1) mRNA in glioma tumor tissues and cells. The effects of miR-320, FoxM1 and sirtuin type 1 (Sirt1) on radiosensitivity in glioma cells were evaluated by clone formation assay, apoptosis assay, histone H2AX phosphorylation level (γH2AX) detection and caspase 3 activity analysis, respectively...
January 10, 2018: Translational Oncology
https://www.readbyqxmd.com/read/29331276/analyzing-recommender-systems-for-health-promotion-using-a-multidisciplinary-taxonomy-a-scoping-review
#2
Santiago Hors-Fraile, Octavio Rivera-Romero, Francine Schneider, Luis Fernandez-Luque, Francisco Luna-Perejon, Anton Civit-Balcells, Hein de Vries
BACKGROUND: Recommender systems are information retrieval systems that provide users with relevant items (e.g., through messages). Despite their extensive use in the e-commerce and leisure domains, their application in healthcare is still in its infancy. These systems may be used to create tailored health interventions, thus reducing the cost of healthcare and fostering a healthier lifestyle in the population. OBJECTIVE: This paper identifies, categorizes, and analyzes the existing knowledge in terms of the literature published over the past 10 years on the use of health recommender systems for patient interventions...
December 28, 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29331186/-addictology-promoting-users-power-to-act
#3
Alain Morel
The notion of risk reduction applies to all uses, drinking of alcohol and smoking including, addictions without drugs likewise. With regard to drugs, mentalities change. We now talk more of risks than fault or deviance. Following, collaboration between health professionals and users, sharing and cooperation are the conditions necessary to develop a modern humanist and social addictology approach.
January 2018: Revue de L'infirmière
https://www.readbyqxmd.com/read/29331101/theory-analysis-for-pender-s-health-promotion-model-hpm-by-barnum-s-criteria-a-critical-perspective
#4
REVIEW
Zohreh Khoshnood, Masoud Rayyani, Batool Tirgari
Background Analysis of nursing theoretical works and its role in knowledge development is presented as an essential process of critical reflection. Health promotion model (HPM) focuses on helping people achieve higher levels of well-being and identifies background factors that influence health behaviors. Objectives This paper aims to evaluate, and critique HPM by Barnum's criteria. Methods The present study reviewed books and articles derived from Proquest, PubMed, Blackwell Databases. The method of evaluation for this model is based on Barnum's criteria for analysis, application and evaluation of nursing theories...
January 13, 2018: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/29330785/genetic-knockdown-and-pharmacologic-inhibition-of-hypoxia-inducible-factor-hif-hydroxylases
#5
Christina Pickel, Cormac T Taylor, Carsten C Scholz
Reduced oxygen supply that does not satisfy tissue and cellular demand (hypoxia) regularly occurs both in health and disease. Hence, the capacity for cellular oxygen sensing is of vital importance for each cell to be able to alter its energy metabolism and promote adaptation to hypoxia. The hypoxia-inducible factor (HIF) prolyl hydroxylases 1-3 (PHD1-3) and the asparagine hydroxylase factor-inhibiting HIF (FIH) are the primary cellular oxygen sensors, which confer cellular oxygen-dependent sensitivity upon HIF as well as other hypoxia-sensitive pathways, such as nuclear factor κB (NF-κB)...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29330149/voluntary-exercise-and-depression-like-behavior-in-rodents-are-we-running-in-the-right-direction
#6
Joram D Mul
Acute or chronic exposure to stress can increase the risk to develop major depressive disorder, a severe, recurrent and common psychiatric condition. Depression places an enormous social and financial burden on modern society. Although many depressed patients are treated with antidepressants, their efficacy is only modest, underscoring the necessity to develop clinically-effective pharmaceutical or behavioral treatments. Exercise training produces beneficial effects on stress-related mental disorders, indicative of clinical potential...
January 12, 2018: Journal of Molecular Endocrinology
https://www.readbyqxmd.com/read/29330081/optimization-of-a-technology-supported-physical-activity-intervention-for-breast-cancer-survivors-fit2thrive-study-protocol
#7
Siobhan M Phillips, Linda M Collins, Frank J Penedo, Kerry S Courneya, Whitney Welch, Alison Cottrell, Gillian R Lloyd, Kara Gavin, David Cella, Ronald T Ackermann, Juned Siddique, Bonnie Spring
Fit2Thrive is a theory-guided physical activity promotion trial using the Multiphase Optimization Strategy (MOST) to test efficacy for improving physical activity of five technology-supported physical activity promotion intervention components among breast cancer survivors. This trial will recruit 256 inactive breast cancer survivors nationwide. All participants will receive the core intervention which includes a Fitbit and standard self-monitoring Fit2Thrive smartphone application which will be downloaded to their personal phone...
January 9, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29329792/-implementation-of-a-health-promotion-programme-for-women-in-social-exclusion-in-the-city-of-seville-spain
#8
Cristina Rodríguez Fernández-Viagas, Carmen García Gil, Nora Bayo Barroso, Cristina Villalba Quesada, Manuela Álvarez Girón
Health promotion can contribute towards reducing inequality and ensuring equal opportunities, providing the means to enable the entire population to develop its maximum health possibilities. Women living in areas with social transformation needs (ASTN) are an especially vulnerable group due to the situation of material deprivation and social exclusion in which they live. Health promotion programmes for this group can bring about an improvement in their health. This paper describes the health promotion programme Socio-educational Groups of Primary Care for Women (SEGPC-W), and evaluates its implementation in ASTN in the city of Seville (Spain), as well as the benefits and difficulties of its development through a documentary analysis and interviews with participating professionals...
January 9, 2018: Gaceta Sanitaria
https://www.readbyqxmd.com/read/29329702/ten-factors-to-consider-when-developing-usability-scenarios-and-tasks-for-health-information-technology
#9
Alissa L Russ, Jason J Saleem
The quality of usability testing is highly dependent upon the associated usability scenarios. To promote usability testing as part of electronic health record (EHR) certification, the Office of the National Coordinator (ONC) for Health Information Technology requires that vendors test specific capabilities of EHRs with clinical end-users and report their usability testing process - including the test scenarios used - along with the results. The ONC outlines basic expectations for usability testing, but there is little guidance in usability texts or scientific literature on how to develop usability scenarios for healthcare applications...
January 9, 2018: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29329571/environmental-exposures-and-fetal-growth-the-haifa-pregnancy-cohort-study
#10
Rachel Golan, Itai Kloog, Ronit Almog, Anat Gesser-Edelsburg, Maya Negev, Maya Jolles, Varda Shalev, Vered H Eisenberg, Gideon Koren, Wiessam Abu Ahmad, Hagai Levine
BACKGROUND: The developing fetus is susceptible to environmental insults. Studying the effects of environmental exposures on fetal growth is essential for understanding the causal pathway between prenatal exposures and pregnancy outcomes. Here we describe the Haifa Pregnancy Cohort Study (HPCS) and discuss challenges and opportunities in applying "big data" paradigm. METHODS: Maccabi Healthcare Services (MHS), is the second largest Israeli health maintenance organization (HMO) providing care services to two million beneficiaries...
January 12, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29329456/designing-and-evaluating-an-automated-system-for-real-time-medication-administration-error-detection-in-a-neonatal-intensive-care-unit
#11
Yizhao Ni, Todd Lingren, Eric S Hall, Matthew Leonard, Kristin Melton, Eric S Kirkendall
Background: Timely identification of medication administration errors (MAEs) promises great benefits for mitigating medication errors and associated harm. Despite previous efforts utilizing computerized methods to monitor medication errors, sustaining effective and accurate detection of MAEs remains challenging. In this study, we developed a real-time MAE detection system and evaluated its performance prior to system integration into institutional workflows. Methods: Our prospective observational study included automated MAE detection of 10 high-risk medications and fluids for patients admitted to the neonatal intensive care unit at Cincinnati Children's Hospital Medical Center during a 4-month period...
January 10, 2018: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29329436/development-of-the-place-based-adelante-social-marketing-campaign-for-prevention-of-substance-use-sexual-risk-and-violence-among-latino-immigrant-youth
#12
E L Andrade, W D Evans, N D Barrett, S D Cleary, M C Edberg, R D Alvayero, E C Kierstead, A Beltran
Immigrant Latino youth represent a high-risk subgroup that should be targeted with health promotion efforts. However, there are considerable barriers to engagement in health-related programming. Little is known about the engagement possibilities of social marketing campaigns and digital strategies for traditionally 'hard-to-reach' immigrants, underscoring the importance of testing these techniques with immigrant Latino adolescents. We developed and piloted a place-based social marketing campaign in coordination with the branded, Positive Youth Development-based (PYD) Adelante intervention targeting risk factors for co-occurring youth substance abuse, sexual risk and violence...
January 9, 2018: Health Education Research
https://www.readbyqxmd.com/read/29326891/role-of-exercise-on-molecular-mechanisms-in-the-regulation-of-antidepressant-effects
#13
REVIEW
Hyo-Jun Lee, Seung-Soo Baek
Regular exercise reduces depressive-like behavior activation. In this study, we look for exact roles of exercise on molecular and neuronal mechanisms for antidepressant action by studying the hippocampal neuroplasticity and proliferation. Increased hippocampal neurogenesis with exercise has potential significance for depression. Exercise promotes brain health in the molecular levels in the hippocampus and also affects behavior in a similar way to chronic antidepressant treatment. Wingless (Wnt) and frizzled signaling system plays an important role in cell proliferation, growth, and differentiation during development...
December 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/29325657/my-quest-an-intervention-using-text-messaging-to-improve-dietary-and-physical-activity-behaviors-and-promote-weight-loss-in-low-income-women
#14
Jamie B Griffin, Barb Struempler, Katie Funderburk, Sondra M Parmer, Cecilia Tran, Danielle D Wadsworth
OBJECTIVE: To evaluate changes in dietary and physical activity behaviors and weight after implementation of a 12-week text messaging initiative (My Quest). DESIGN: The researchers conducted a 1-group, pre- to posttest study design to determine changes after implementation of a text messaging initiative developed using the tenets of the Social Cognitive Theory. SETTING: A total of 55 Alabama counties (84% rural) with high rates of poverty, overweight/obesity, and chronic diseases...
January 2018: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/29325552/health-care-access-for-rural-youth-on-equal-terms-a-mixed-methods-study-protocol-in-northern-sweden
#15
Isabel Goicolea, Dean Carson, Miguel San Sebastian, Monica Christianson, Maria Wiklund, Anna-Karin Hurtig
BACKGROUND: The purpose of this paper is to propose a protocol for researching the impact of rural youth health service strategies on health care access. There has been no published comprehensive assessment of the effectiveness of youth health strategies in rural areas, and there is no clearly articulated model of how such assessments might be conducted. The protocol described here aims to gather information to; i) Assess rural youth access to health care according to their needs, ii) Identify and understand the strategies developed in rural areas to promote youth access to health care, and iii) Propose actions for further improvement...
January 11, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29325443/moving-upstream-in-health-promoting-policies-for-older-people-with-early-frailty-in-england-a-policy-analysis
#16
Vari Drennan, Kate Walters, Christina Avgerinou, Benjamin Gardner, Claire Goodman, Rachael Frost, Kalpa Kharicha, Steve Iliffe, Jill Manthorpe
Objectives Globally, populations are rapidly ageing and countries have developed health promotion and wellbeing strategies to address increasing demand for health care and old-age support. The older population is not homogeneous however, and includes a large group in transition between being active and healthy to being frail, i.e. with early frailty. This review explores the extent to which policy in England has addressed this group with a view to supporting independence and preventing further progression towards frailty...
January 1, 2018: Journal of Health Services Research & Policy
https://www.readbyqxmd.com/read/29325417/rhubarb-supplementation-promotes-intestinal-mucosal-innate-immune-homeostasis-through-modulating-intestinal-epithelial-microbiota-in-goat-kids
#17
Jinzhen Jiao, Jian Wu, Min Wang, Chuanshe Zhou, Rong-Zhen Zhong, Zhi-Liang Tan
The abuse and misuse of antibiotics in livestock production pose a potential health risk globally. Rhubarb can serve as a potential alternative to antibiotics, and several studies have looked into its anti-cancer, anti-tumor and anti-inflammatory properties. The aim of this study was to test the effects of rhubarb supplementation to the diet of young ruminants on innate immune function and epithelial microbiota in the small intestine. Goat kids were fed with a control diet supplemented with or without rhubarb (1...
January 11, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29325127/inhibiting-trophoblast-par-1-overexpression-suppresses-sflt-1-induced-anti-angiogenesis-and-abnormal-vascular-remodeling-a-possible-therapeutic-approach-for-preeclampsia
#18
Yin Zhao, YanFang Zheng, XiaoXia Liu, QingQing Luo, Di Wu, XiaoPing Liu, Li Zou
STUDY QUESTION: Is it possible to improve vascular remodeling by inhibiting the excessive expression of protease activated receptor 1 (PAR-1) in trophoblast of abnormal placenta? SUMMARY ANSWER: Inhibition of trophoblast PAR-1 overexpression may promote placental angiogenesis and vascular remodeling, offering an alternative therapeutic approach for preeclampsia. WHAT IS KNOWN ALREADY: PAR-1 is high-affinity receptor of thrombin. Thrombin increases sFlt-1 secretion in trophoblast via the activation of PAR-1...
January 9, 2018: Molecular Human Reproduction
https://www.readbyqxmd.com/read/29324949/training-of-adolescent-multipliers-from-the-perspective-of-health-promotion-core-competencies
#19
Kely Vanessa Leite Gomes da Silva, Gleice Adriana Araújo Gonçalves, Shayane Bezerra Dos Santos, Maria de Fatima Antero Sousa Machado, Cristiana Brasil de Almeida Rebouças, Viviane Martins da Silva, Lorena Barbosa Ximenes
OBJECTIVE: Recognize the domains of health promotion core competencies in the training process of adolescents carried out by nursing students. METHOD: Qualitative and descriptive study, which used the theoretical methodological contribution Developing Competencies and Professional Standards for Health Promotion Capacity Building in Europe (CompHP), carried out with 14 nursing students. RESULTS: There were four domains: Enable Change; Mediate through Partnership; Communication; and Leadership...
January 2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29324773/the-impact-of-a-short-term-cohousing-initiative-among-schizophrenia-patients-high-school-students-and-their-social-context-a-qualitative-case-study
#20
Domingo Palacios-Ceña, Emilio Andrés Martín-Tejedor, Ana Elías-Elispuru, Amaia Garate-Samaniego, Jorge Pérez-Corrales, Elena García-García
BACKGROUND: A number of programs have been developed to promote the contact between adolescents and mentally-ill patients, in order to break the stigma, improve understanding, promote mental health and prevent substance abuse. The aim of this study was to describe the experience of patients with schizophrenia, high school students, and their social context, participating in a short-term cohousing initiative. METHODS: A qualitative case-study approach was implemented...
2018: PloS One
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