Read by QxMD icon Read

transfer of accountability

Stefano Iubini, Pierfrancesco Di Cintio, Stefano Lepri, Roberto Livi, Lapo Casetti
We investigate thermal conduction in arrays of long-range interacting rotors and Fermi-Pasta-Ulam (FPU) oscillators coupled to two reservoirs at different temperatures. The strength of the interaction between two lattice sites decays as a power α of the inverse of their distance. We point out the necessity of distinguishing between energy flows towards or from the reservoirs and those within the system. We show that energy flow between the reservoirs occurs via a direct transfer induced by long-range couplings and a diffusive process through the chain...
March 2018: Physical Review. E
Guillaume Dechristé, Jérôme Fehrenbach, Elena Griseti, Valérie Lobjois, Clair Poignard
BACKGROUND: Since several decades, the experiments have highlighted the analogy of fusing cell aggregates with liquid droplets. The physical macroscopic models have been derived under incompressible assumptions. The aim of this paper is to provide a 3D model of growing spheroids, which is more relevant regarding embryo cell aggregates or tumor cell spheroids. METHODS: We extend the past approach to a compressible 3D framework in order to account for the tumor spheroid growth...
May 15, 2018: Journal of Theoretical Biology
Erika N Bentz, Rosana Maria Lobayan, Henar Martinez, Pilar Redondo, Antonio Largo
A computational kinetics study of the antioxidant activity of tryptamine toward HO● and HOO● radicals in water at 298 K has been carried out. Density functional methods have been employed for the quantum chemical calculations and conventional transition state theory was used for rate constants evaluation. Different mechanisms have been considered: radical adduct formation (RAF), single electron transfer (SET), and hydrogen atom transfer (HAT). For the reaction of tryptamine with the hydroxyl radical nearly all channels are diffusion controlled, and the overall rate constant is very high, 6...
May 18, 2018: Journal of Physical Chemistry. B
Tobias Talanow, Ulrich Ettinger
Executive functions (EFs) comprise the updating, shifting and inhibition dimensions. According to the Unity and Diversity Model, the inhibition dimension is fully accounted for by a general EFs factor. This suggests that training of inhibition should transfer, in part, to updating and shifting. Therefore, we tested the effectiveness of a three-week inhibition training (high-conflict Stroop task) and explored near transfer effects to an untrained inhibition task (antisaccade task) and far transfer effects to untrained tasks demanding task-set shifting (number-letter-task), working memory updating (n-back task) and planning abilities (Stockings of Cambridge task)...
May 14, 2018: Acta Psychologica
Didier Raboisson, Pauline Trillat, Marie Dervillé, Célia Cahuzac, Elise Maigné
There is extensive literature addressing acceptable practices of colostrum distribution to new-born calves; however, no economic analyses are available concerning the profitability of this practice. Moreover, the health standards associated with colostrum management have been defined through the observation of reference farms without explicit reference to economic assessments. The objective of the current study was to evaluate the profitability of farm colostrum management and to define the optimal economic situations for given livestock systems and farm situations...
2018: PloS One
Simone C Vitor, Luciano do Amarante, Ladaslav Sodek
A substantial increase in malate in the xylem sap of soybean subjected to mineral N starvation originates mainly from aspartate, a prominent amino acid of the phloem. A substantial increase in xylem malate was found when non-nodulated soybean plants were transferred to a N-free medium. Nodulated plants growing in the absence of mineral N and, therefore, dependent on symbiotic N2 fixation also contained elevated concentrations of malate in the xylem sap. When either nitrate or ammonium was supplied, malate concentrations in the xylem sap were low, both for nodulated and non-nodulated plants...
May 16, 2018: Planta
Rachelle L Stammen, Joyce K Cohen, Tracy L Meeker, Maria M Crane, Rama R Amara, Sakeenah L Hicks, Jerrold S Meyer, Kelly F Ethun
Because tetanus can cause significant morbidity and mortality in NHP, colonywide vaccination with tetanus toxoid is recommendedfor outdoor breeding colonies of rhesus macaques, with primary immunizations commonly given to infants at 6 mo of age followed by booster vaccines every 10 y. Maternal antibodies are thought to offer protective immunity to infants younger than 6 mo. However, historical colony data from the Yerkes National Primate Research Center show a higher incidence of tetanus among infants (≤ 6 mo old) born to subordinate dams...
May 15, 2018: Journal of the American Association for Laboratory Animal Science: JAALAS
Chandani Singh, Subhabrata Mukhopadhyay, Samar K Das
A polyoxometalate (POM)-supported nickel(II) coordination complex, [NiII (2,2'-bpy)3 ]3 [{NiII (2,2'-bpy)2 (H2 O)}{HCoII WVI 12 O40 }]2 ·3H2 O (1; 2,2'-bpy = 2,2'-bipyridine), has been synthesized and structurally characterized. We could obtain a relatively better resolved structure from dried crystals of 1, NiII (2,2'-bpy)3 ]3 [{NiII (2,2'-bpy)2 (H2 O)}{HCoII WVI 12 O40 }]2 ·H2 O (D1). Because the title compound has been characterized with a {NiII (2,2'-bpy)2 (H2 O)}2+ fragment coordinated to the surface of the Keggin anion ([H(CoII W12 O40 ]5- ) via a terminal oxo group of tungsten and the [NiII (2,2'-bpy)3 ]2+ coordination complex cation sitting as the lattice component in the concerned crystals, the electronic spectroscopy of compound 1 has been described by comparing its electronic spectral features with those of [NiII (2,2'-bpy)2 (H2 O)Cl]Cl, [NiII (2,2'-bpy)3 ]Cl2 , and K6 [CoII W12 O40 ]·6H2 O...
May 15, 2018: Inorganic Chemistry
Fatima Sheikh, Evelyn Gathecha, Michele Bellantoni, Colleen Christmas, Justin P Lafreniere, Alicia I Arbaje
BACKGROUND: Older adults with complex medical conditions are vulnerable during care transitions. Poor care transitions can lead to poor patient outcomes and frequent readmissions to the hospital. FACTORS CONTRIBUTING TO SUBOPTIMAL CARE TRANSITIONS: Key factors related to ineffective care transitions, which can lead to suboptimal patient outcomes, include poor cross-site communication and collaboration; lack of awareness of patient wishes, abilities, and goals of care; and incomplete medication reconciliation...
May 2018: Joint Commission Journal on Quality and Patient Safety
Xingcheng Lin, Susmita Roy, Mohit Kumar Jolly, Federico Bocci, Nicholas P Schafer, Min-Yeh Tsai, Yihong Chen, Yanan He, Alexander Grishaev, Keith Weninger, John Orban, Prakash Kulkarni, Govindan Rangarajan, Herbert Levine, José N Onuchic
Prostate-Associated Gene 4 (PAGE4) is an intrinsically disordered protein (IDP) implicated in prostate cancer. The stress-response kinase Homeodomain-Interacting Protein Kinase 1 (HIPK1) phosphorylates two residues in PAGE4, serine 9 and threonine 51. Phosphorylation of these two residues facilitates the interaction of PAGE4 with Activator Protein-1 (AP-1) transcription factor complex to potentiate AP-1's activity. In contrast, hyperphosphorylation of PAGE4 by CDC-Like Kinase 2 (CLK2) attenuates this interaction with AP-1...
May 11, 2018: Journal of Molecular Biology
G Voiriot, M Chalumeau, J Messika, D Basille, B Philippe, J-D Ricard, C Andrejak, V Jounieaux, O Sanchez, M Fartoukh
INTRODUCTION: Outpatient treatment of community-acquired pneumonia (CAP) patients with non-steroidal anti-inflammatory drugs (NSAIDs) is frequent, although this is not based on clinical recommendations and there is no scientific evidence supporting better symptom relief in comparison to acetaminophen. STATE OF THE ART: Experimental data suggest that NSAIDs alter the intrinsic functions of neutrophils, limit their locoregional recruitment, alter bacterial clearance and delay the resolution of inflammatory processes during acute bacterial pulmonary challenge...
May 10, 2018: Revue des Maladies Respiratoires
Alberto Sánchez-Pascuala, Pablo I Nikel, Víctor de Lorenzo
The Embden-Meyerhof-Parnas (EMP) pathway is widely accepted to be the biochemical standard of glucose catabolism. The well-characterized glycolytic route of Escherichia coli, based on the EMP catabolism, is an example of an intricate pathway in terms of genomic organization of the genes involved and patterns of gene expression and regulation. This intrinsic genetic and metabolic complexity renders it difficult to engineer glycolytic activities and transfer them onto other microbial cell factories, thus limiting the biotechnological potential of bacterial hosts that lack the route...
2018: Methods in Molecular Biology
A Lara, M Riquelme, E Vöhringer-Martinez
Partition coefficients serve in various areas as pharmacology and environmental sciences to predict the hydrophobicity of different substances. Recently, they have also been used to address the accuracy of force fields for various organic compounds and specifically the methylated DNA bases. In this study, atomic charges were derived by different partitioning methods (Hirshfeld and Minimal Basis Iterative Stockholder) directly from the electron density obtained by electronic structure calculations in a vacuum, with an implicit solvation model or with explicit solvation taking the dynamics of the solute and the solvent into account...
May 11, 2018: Journal of Computational Chemistry
Reza Erfani, Fatemeh Marefat, Amir M Sodagar, Pedram Mohseni
This paper reports on the modeling and characterization of capacitive elements with tissue as the dielectric material, representing the core building block of a capacitive link for wireless power transfer to neural implants. Each capacitive element consists of two parallel plates that are aligned around the tissue layer and incorporate a grounded, guarded, capacitive pad to mitigate the adverse effect of stray capacitances and shield the plates from external interfering electric fields. The plates are also coated with a biocompatible, insulating, coating layer on the inner side of each plate in contact with the tissue...
May 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
Weijia Liu, Yuyang Long, Yuan Fang, Luyao Ying, Dongsheng Shen
It is thought that mineralized refuse could be excavated from almost-full landfill sites to provide space for the increasing burden of municipal solid waste. When excavating, however, the H2 S emissions from the mineralized waste need to be considered carefully. In an attempt to understand how H2 S emissions might change during this excavation process, we carried out a series of tests, including exposing anaerobic mineralized refuse to oxygen, isolating and determining possible functional bacteria, and characterizing the electron donors and/or acceptors...
May 8, 2018: Science of the Total Environment
Jenifer Gómez-Pastora, Cristina González-Fernández, Eusebio Real, Alexander Iles, Eugenio Bringas, Edward P Furlani, Inmaculada Ortiz
Magnetic beads can be functionalized to capture and separate target pathogens from blood for extracorporeal detoxification. The beads can be magnetically separated from a blood stream and collected into a coflowing buffer solution using a two-phase liquid-liquid continuous-flow microfluidic device in the presence of an external field. However, device design and process optimization, i.e. high bead recovery with minimum blood loss or dilution remain a substantial technological challenge. We introduce a CFD-based Eulerian-Lagrangian computational model that enables the rational design and optimization of such systems...
May 11, 2018: Lab on a Chip
Guang Fu, David Z Zhang, Allen N He, Zhongfa Mao, Kaifei Zhang
A deep understanding of the laser-material interaction mechanism, characterized by laser absorption, is very important in simulating the laser metal powder bed fusion (PBF) process. This is because the laser absorption of material affects the temperature distribution, which influences the thermal stress development and the final quality of parts. In this paper, a three-dimensional finite element analysis model of heat transfer taking into account the effect of material state and phase changes on laser absorption is presented to gain insight into the absorption mechanism, and the evolution of instantaneous absorptance in the laser metal PBF process...
May 10, 2018: Materials
J Shen, L L Gao, Y Zhang, L L Han, J D Wang
Objective: To study the prevalence of high-risk HPV (HR HPV) in women who accepted cervical cancer screening in Beijing and its distribution in cervical precancerous lesions. Methods: From January 2014 to March 2015, all women aged 35-64 years old and received free screening in institutions of cervical cancer in Beijing were recruited. Stratified cluster random sampling method was used in selecting 31 091 women for gynecological examination and genotyping of HR-HPV. Those positive for HR-HPV (except for HPV 16/18) were examined for cervical cell...
May 6, 2018: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
Barbara J King, Andrea L Gilmore-Bykovskyi, Tonya J Roberts, Korey A Kennelty, Jacquelyn F Mirr, Michael B Gehring, Melissa N Dattalo, Amy J H Kind
Background: Twenty-five percentage of patients who are transferred from hospital settings to skilled nursing facilities (SNFs) are rehospitalized within 30 days. One significant factor in poorly executed transitions is the discharge process used by hospital providers. Objective: The objective of this study was to examine how health care providers in hospitals transition care from hospital to SNF, what actions they took based on their understanding of transitioning care, and what conditions influence provider behavior...
May 8, 2018: Gerontologist
Cuiying Song, Wei Guan, Jihui Ma
Public transport (PT) is a key element in most major cities around the world. With the development of smartphones, available journey planning information is becoming an integral part of the PT system. Each traveler has specific preferences when undertaking a trip, and these preferences can also be reflected on the smartphone. This paper considers transit assignment in urban public-transport networks in which the passengers receive smartphone-based information containing elements that might influence the travel decisions in relation to line loads, as well as passenger benefits, and the paper discusses the transition from the current widespread choosing approach to a personalized decision-making approach based on smartphone information...
2018: PloS One
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"