Maude Giroud, Foivos-Filippos Tsokanos, Giorgio Caratti, Stefan Kotschi, Sajjad Khani, Céline Jouffe, Elena S Vogl, Martin Irmler, Christina Glantschnig, Manuel Gil-Lozano, Daniela Hass, Asrar Ali Khan, Marcos Rios Garcia, Frits Mattijssen, Adriano Maida, Daniel Tews, Pamela Fischer-Posovszky, Annette Feuchtinger, Kirsi A Virtanen, Johannes Beckers, Martin Wabitsch, Henriette Uhlenhaut, Matthias Blüher, Jan Tuckermann, Marcel Scheideler, Alexander Bartelt, Stephan Herzig
AIMS/HYPOTHESIS: Adipocytes are critical cornerstones of energy metabolism. While obesity-induced adipocyte dysfunction is associated with insulin resistance and systemic metabolic disturbances, adipogenesis, the formation of new adipocytes and healthy adipose tissue expansion are associated with metabolic benefits. Understanding the molecular mechanisms governing adipogenesis is of great clinical potential to efficiently restore metabolic health in obesity. Here we investigate the role of heart and neural crest derivatives-expressed 2 (HAND2) in adipogenesis...
May 20, 2021: Diabetologia