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https://www.readbyqxmd.com/read/28440561/anterior-st-elevation-myocardial-infarction-induced-by-rituximab-infusion-a-case-report-and-review-of-the-literature
#1
K Sharif, A Watad, N L Bragazzi, E Asher, A Abu Much, Y Horowitz, M Lidar, Y Shoenfeld, H Amital
WHAT IS KNOWN AND OBJECTIVES: Rituximab is a chimeric monoclonal anti-CD20 antibody approved for the treatment of some lymphoid malignancies as well as for autoimmune diseases including rheumatoid arthritis (RA), idiopathic thrombocytopenic purpura (ITP) and vasculitis. Generally, rituximab is well tolerated; nevertheless, some patients develop adverse effects including infusion reactions. Albeit rare, these reactions may in some cases be life-threatening conditions. Rituximab cardiovascular side effects include more common effects such as hypertension, oedema and rare cases of arrhythmias and myocardial infarction...
June 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28439641/data-driven-metabolic-subtypes-predict-future-adverse-events-in-individuals-with-type-1-diabetes
#2
Raija Lithovius, Iiro Toppila, Valma Harjutsalo, Carol Forsblom, Per-Henrik Groop, Ville-Petteri Mäkinen
AIMS/HYPOTHESIS: Previously, we proposed that data-driven metabolic subtypes predict mortality in type 1 diabetes. Here, we analysed new clinical endpoints and revisited the subtypes after 7 years of additional follow-up. METHODS: Finnish individuals with type 1 diabetes (2059 men and 1924 women, insulin treatment before 35 years of age) were recruited by the national multicentre FinnDiane Study Group. The participants were assigned one of six metabolic subtypes according to a previously published self-organising map from 2008...
April 24, 2017: Diabetologia
https://www.readbyqxmd.com/read/28431077/implantable-cardioverter-defibrillator-use-for-primary-prevention-in-ischaemic-and-non-ischaemic-heart-disease-indications-in-the-post-danish-trial-era-results-of-the-european-heart-rhythm-association-survey
#3
Kristina H Haugaa, Roland Tilz, Serge Boveda, Dan Dobreanu, Elena Sciaraffia, Jacques Mansourati, Giorgi Papiashvili, Nikolaos Dagres
Implantable cardioverter-defibrillator (ICD) is the standard of care for prevention of sudden cardiac death (SCD) in high-risk patients. For primary prevention of SCD, in patients with ischaemic heart disease, there is more robust data on the effect of ICD therapy compared with patients with non-ischaemic heart disease, but current real-life practice may differ substantially. The aim of this European Heart Rhythm Association survey was to evaluate the clinical practice regarding implantation of ICD for primary prevention among European countries in patients with non-ischaemic and ischaemic heart disease...
April 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28430901/synergistic-effect-between-ischaemic-heart-disease-and-common-mental-disorders-and-the-risk-of-premature-exit-from-the-labour-market-a-nationwide-register-based-study-from-sweden
#4
Ellenor Mittendorfer-Rutz, Torbjörn Ivert, Marjan Vaez, Thomas Ernst Dorner
Aims: Common mental disorders i.e. depressive and anxiety disorders (CMD) are frequent comorbid conditions in individuals with ischaemic heart disease (IHD). Still, their effect on preterm exit from the labour market [i.e. disability pension (DP)] in individuals with IHD has to date not been scrutinized. The aim of this study was to investigate the separate and joint effect of IHD and CMD on the risk of DP for women and men of working age. Material and methods: This population-based cohort study included all non-pensioned 4 823 069 individuals, registered as living in Sweden 31 December 2004 and then 16-64 years of age...
April 18, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28425011/pregnancy-related-myocardial-infarction
#5
H Lameijer, M C Lont, H Buter, A J van Boven, P W Boonstra, P G Pieper
INTRODUCTION: The risk of acute myocardial infarction in young women is low, but increases during pregnancy due to the physiological changes in pregnancy, including hypercoagulability. Ischaemic heart disease during pregnancy is not only associated with increased maternal morbidity and mortality, but also with high neonatal complications. Advancing maternal age and other risk factors for cardiovascular diseases may further increase the risk of ischaemic heart disease in young women. METHODS: We searched the coronary angiography database of a Dutch teaching hospital to identify women with acute myocardial infarction who presented during pregnancy or postpartum between 2011 and 2013...
April 19, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/28417034/knowledge-regarding-secondary-prevention-lifestyle-practices-among-patients-with-ischaemic-heart-disease-in-oman-pilot-study
#6
Tamim R Al-Tamimi, Hafidh A Ba-Omar, Sunil Nadar
OBJECTIVES: Secondary prevention of ischaemic heart disease (IHD) is very important. This study aimed to assess knowledge of necessary lifestyle changes among Omani patients diagnosed with IHD. METHODS: This cross-sectional pilot study took place between October 2015 and February 2016 at the Sultan Qaboos University Hospital (SQUH), Muscat, Oman. A total of 30 random patients with IHD from the Cardiology Outpatient Clinic of SQUH were included. A 30-item survey was used to determine patients' knowledge of necessary lifestyle practices following their IHD diagnosis, with scores of <70% indicating poor knowledge...
February 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/28415112/clinical-cases-ischaemic-heart-disease
#7
(no author information available yet)
No abstract text is available yet for this article.
December 1, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28409004/effect-of-%C3%AE-blockade-on-lung-function-exercise-performance-and-dynamic-hyperinflation-in-people-with-arterial-vascular-disease-with-and-without-copd
#8
Angela Key, Matthew Parry, Malcolm A West, Rebecca Asher, Sandy Jack, Nick Duffy, Francesco Torella, Paul P Walker
INTRODUCTION: β Blockers are important treatment for ischaemic heart disease and heart failure; however, there has long been concern about their use in people with chronic obstructive pulmonary disease (COPD) due to fear of symptomatic worsening of breathlessness. Despite growing evidence of safety and efficacy, they remain underused. We examined the effect of β-blockade on lung function, exercise performance and dynamic hyperinflation in a group of vascular surgical patients, a high proportion of who were expected to have COPD...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/28408086/estimates-and-25-year-trends-of-the-global-burden-of-disease-attributable-to-ambient-air-pollution-an-analysis-of-data-from-the-global-burden-of-diseases-study-2015
#9
Aaron J Cohen, Michael Brauer, Richard Burnett, H Ross Anderson, Joseph Frostad, Kara Estep, Kalpana Balakrishnan, Bert Brunekreef, Lalit Dandona, Rakhi Dandona, Valery Feigin, Greg Freedman, Bryan Hubbell, Amelia Jobling, Haidong Kan, Luke Knibbs, Yang Liu, Randall Martin, Lidia Morawska, C Arden Pope, Hwashin Shin, Kurt Straif, Gavin Shaddick, Matthew Thomas, Rita van Dingenen, Aaron van Donkelaar, Theo Vos, Christopher J L Murray, Mohammad H Forouzanfar
BACKGROUND: Exposure to ambient air pollution increases morbidity and mortality, and is a leading contributor to global disease burden. We explored spatial and temporal trends in mortality and burden of disease attributable to ambient air pollution from 1990 to 2015 at global, regional, and country levels. METHODS: We estimated global population-weighted mean concentrations of particle mass with aerodynamic diameter less than 2·5 μm (PM2·5) and ozone at an approximate 11 km × 11 km resolution with satellite-based estimates, chemical transport models, and ground-level measurements...
April 10, 2017: Lancet
https://www.readbyqxmd.com/read/28404197/mercaptopurine-versus-placebo-to-prevent-recurrence-of-crohn-s-disease-after-surgical-resection-toppic-a-multicentre-double-blind-randomised-controlled-trial
#10
Craig Mowat, Ian Arnott, Aiden Cahill, Malcolm Smith, Tariq Ahmad, Sreedhar Subramanian, Simon Travis, John Morris, John Hamlin, Anjan Dhar, Chuka Nwokolo, Cathryn Edwards, Tom Creed, Stuart Bloom, Mohamed Yousif, Linzi Thomas, Simon Campbell, Stephen J Lewis, Shaji Sebastian, Sandip Sen, Simon Lal, Chris Hawkey, Charles Murray, Fraser Cummings, Jason Goh, James O Lindsay, Naila Arebi, Lindsay Potts, Aileen J McKinley, John M Thomson, John A Todd, Mhairi Collie, Malcolm G Dunlop, Ashley Mowat, Daniel R Gaya, Jack Winter, Graham D Naismith, Holly Ennis, Catriona Keerie, Steff Lewis, Robin J Prescott, Nicholas A Kennedy, Jack Satsangi
BACKGROUND: Up to 60% of patients with Crohn's disease need intestinal resection within the first 10 years of diagnosis, and postoperative recurrence is common. We investigated whether mercaptopurine can prevent or delay postoperative clinical recurrence of Crohn's disease. METHODS: We did a randomised, placebo-controlled, double-blind trial at 29 UK secondary and tertiary hospitals of patients (aged >16 years in Scotland or >18 years in England and Wales) who had a confirmed diagnosis of Crohn's disease and had undergone intestinal resection...
December 2016: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28403155/fruit-consumption-and-physical-activity-in-relation-to-all-cause-and-cardiovascular-mortality-among-70-000-chinese-adults-with-pre-existing-vascular-disease
#11
Xiaocao Tian, Huaidong Du, Liming Li, Derrick Bennett, Ruqin Gao, Shanpeng Li, Shaojie Wang, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Junshi Chen, Yan Gao, Min Weng, Zengchang Pang, Baofa Jiang, Zhengming Chen
OBJECTIVES: To assess the associations of fresh fruit consumption and total physical activity with all-cause and cardiovascular mortality among Chinese adults who have been diagnosed with cardiovascular disease (CVD) or hypertension. METHODS: During 2004-08, the China Kadoorie Biobank study recruited 70,047 adults, aged 30-79 years, with physician-diagnosed stroke or transient ischaemic attack, ischemic heart disease, or hypertension. Information on diet and physical activity was collected using an interviewer-administered electronic questionnaire...
2017: PloS One
https://www.readbyqxmd.com/read/28399109/tyrosine-kinase-targeting-drugs-associated-heart-failure
#12
N Gronich, I Lavi, O Barnett-Griness, W Saliba, D R Abernethy, G Rennert
BACKGROUND: The impact of cancer therapies on cardiac disease in the general adult cancer survivor population is largely unknown. Our objective was to evaluate which tyrosine kinase-targeting drugs are associated with greater risk for new-onset heart failure (HF). METHODS: A nested case-control analysis was conducted within a cohort of 27 992 patients of Clalit Health Services, newly treated with a tyrosine kinase-targeting, and/or chemotherapeutic drug, for a malignant disease, between 1 January 2005 and 31 December 2012...
April 11, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28397699/restrictive-versus-liberal-blood-transfusion-for-gastrointestinal-bleeding-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#13
Ayodele Odutayo, Michael J R Desborough, Marialena Trivella, Adrian J Stanley, Carolyn Dorée, Gary S Collins, Sally Hopewell, Susan J Brunskill, Brennan C Kahan, Richard F A Logan, Alan N Barkun, Michael F Murphy, Vipul Jairath
BACKGROUND: Acute upper gastrointestinal bleeding is a leading indication for red blood cell (RBC) transfusion worldwide, although optimal thresholds for transfusion are debated. METHODS: We searched MEDLINE, Embase, CENTRAL, CINAHL, and the Transfusion Evidence Library from inception to Oct 20, 2016, for randomised controlled trials comparing restrictive and liberal RBC transfusion strategies for acute upper gastrointestinal bleeding. Main outcomes were mortality, rebleeding, ischaemic events, and mean RBC transfusion...
May 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28397639/intake-of-different-dietary-proteins-and-risk-of-type-2-diabetes-in-men-the-kuopio-ischaemic-heart-disease-risk-factor-study
#14
Heli E K Virtanen, Timo T Koskinen, Sari Voutilainen, Jaakko Mursu, Tomi-Pekka Tuomainen, Petra Kokko, Jyrki K Virtanen
The roles of different dietary proteins in the aetiology of type 2 diabetes (T2D) remain unclear. We investigated the associations of dietary proteins with the risk of incident T2D in Finnish men from the prospective Kuopio Ischaemic Heart Disease Risk Factor Study. The study included 2332 men aged 42-60 years at the baseline examinations in 1984-1989. Protein intakes were calculated from 4-d dietary records. Incident T2D was determined by self-administered questionnaires, fasting blood glucose measurements, 2-h oral glucose tolerance tests, and with national registers...
April 11, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28396699/can-the-onset-of-heart-failure-be-delayed-by-treating-diabetic-cardiomyopathy
#15
REVIEW
Anna Marcinkiewicz, Stanisław Ostrowski, Józef Drzewoski
The pathophysiology of diabetic cardiomyopathy (DC) is not fully understood. This frequently undiagnosed complication of chronic hyperglycemia leads to heart failure (HF). However, it is suggested that an appropriate metabolic control of diabetes at an early stage of this deleterious disease, is able to inhibit the development and progression of DC to HF. Recently, it has been postulated that myocardial ischaemia plays an important role in the development of this pathology. Results of the antianginal pharmacological treatment and revascularization are unsatisfactory and reveal a gap in our knowledge and current approaches to treating DC...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28393705/antithrombotic-therapy-for-transcatheter-valvular-interventions-a-revisit
#16
Shaban Mohammed, Ayman El-Menyar, Haifa Al-Janubi, Adel Shabana, Zaid Alanazi
The optimal antithrombotic therapies for transcatheter aortic valve implantation (TAVI) and MitraClip implantation have not been well established. We conducted a narrative review from currently available studies between January 2002 and May 2016 to highlight the advantages and disadvantages of antithrombotic therapy use in cardiac catheter-based therapeutic techniques. Recently, these techniques have dramatically altered the approach towards valvular heart diseases management. The introduction into clinical practice, of TAVI for severe aortic stenosis and MitraClip for mitral regurgitation, has revolutionized interventional cardiology...
April 6, 2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/28391245/mortality-and-cancer-incidence-among-male-volunteer-australian-firefighters
#17
Deborah C Glass, Anthony Del Monaco, Sabine Pircher, Stephen Vander Hoorn, Malcolm R Sim
OBJECTIVES: This study aims to investigate mortality and cancer incidence of Australian male volunteer firefighters and of subgroups of firefighters by duration of service, era of first service and the number and type of incidents attended. METHODS: Participating fire agencies supplied records of individual volunteer firefighters, including incidents attended. The cohort was linked to the Australian National Death Index and Australian Cancer Database. standardised mortality ratios (SMRs) and standardised incidence ratios (SIRs) for cancer were calculated...
April 8, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28390852/cardiovascular-comorbidity-in-patients-with-chronic-obstructive-pulmonary-disease-in-the-canary-islands-ccecan-study
#18
Juan Marco Figueira Gonc Alves, Rafael Dorta Sánchez, María Del Cristo Rodri Guez Pérez, Pedro Viña Manrique, David Díaz Pérez, Cristina Guzmán Saenz, Juan Manuel Palmero Tejera, Alicia Pérez Rodríguez, Lorenzo Pérez Negrín
INTRODUCTION: Numerous studies have shown a high prevalence of cardiovascular disease in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to analyse the prevalence of cardiovascular risk factors and comorbidity in a Canary Islands population diagnosed with COPD, and compared it with data from the general population. PATIENTS AND METHODS: A cross-sectional study was carried out in 300 patients with COPD and 524 subjects without respiratory disease (control group)...
April 5, 2017: Clínica e Investigación en Arteriosclerosis
https://www.readbyqxmd.com/read/28389491/prevalence-based-disease-specific-estimate-of-the-social-cost-of-smoking-in-singapore
#19
Boon Piang Cher, Cynthia Chen, Joanne Yoong
OBJECTIVE: To estimate the cost of smoking in Singapore in 2014 from the societal perspective. METHODS: A prevalence-based, disease-specific approach was undertaken to estimate the smoking-attributable costs. These include direct and indirect costs of inpatient treatment, premature mortality, loss of productivity due to medical leaves and smoking breaks. RESULTS: In 2014, the social cost of smoking in Singapore was conservatively estimated to be at least US$479...
April 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28389252/the-impact-of-patient-demographics-anatomy-comorbidities-and-peri-operative-planning-on-the-primary-functional-maturation-of-autogenous-radiocephalic-arteriovenous-fistula
#20
A Kordzadeh, A Askari, M Hoff, V Smith, Y Panayiotopoulos
OBJECTIVES: The aim of this study was to evaluate the collective and/or independent impact of patient demographics, comorbidities, anatomical factors, and peri-operative parameters on the primary functional maturation of RCAVFs. This study also aimed to identify the range and best cut off value for each variable and evaluate the likelihood, significance and percentage of primary functional maturation of RCAVFs. METHODS: This was a prospective consecutive single centre cohort study over a 4 year period; it was conducted on patients with the intention-to-treat using a radiocephalic arteriovenous fistula (RCAVF) (Brescia-Cimino)...
April 4, 2017: European Journal of Vascular and Endovascular Surgery
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