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https://www.readbyqxmd.com/read/29453329/management-characteristics-and-outcomes-of-patients-with-acute-coronary-syndrome-in-sri-lanka
#1
Priyadarshani Galappatthy, Vipula R Bataduwaarachchi, Priyanga Ranasinghe, Gamini K S Galappatthy, Maheshi Wijayabandara, Dinuka S Warapitiya, Mythily Sivapathasundaram, Thilini Wickramarathna, Upul Senarath, Sathasivam Sridharan, Chandrika N Wijeyaratne, Ruvan Ekanayaka
BACKGROUND: Ischaemic heart disease is the leading cause of in-hospital mortality in Sri Lanka. Acute Coronary Syndrome Sri Lanka Audit Project (ACSSLAP) is the first national clinical-audit project that evaluated patient characteristics, clinical outcomes and care provided by state-sector hospitals. METHODS: ACSSLAP prospectively evaluated acute care, in-hospital care and discharge plans provided by all state-sector hospitals managing patients with ACS. Data were collected from 30 consecutive patients from each hospital during 2-4 weeks window...
February 16, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29449425/young-and-middle-aged-adults-with-airflow-limitation-according-to-lower-limit-of-normal-but-not-fixed-ratio-have-high-morbidity-and-poor-survival-a-population-based-prospective-cohort-study
#2
Yunus Çolak, Shoaib Afzal, Børge G Nordestgaard, Jørgen Vestbo, Peter Lange
A presumed consequence of using a fixed ratio for the definition of airflow limitation (AFL) has been overdiagnosis among older and underdiagnosis among younger individuals. However, the prognosis of younger individuals with potentially underdiagnosed airflow limitation is poorly described. We hypothesised that potential underdiagnosis of AFL at younger age is associated with poor prognosis.We assigned 95 288 participants aged 20-100 years from the Copenhagen General Population Study into: individuals without AFL with forced expiratory volume in 1 s (FEV 1 )/forced vital capacity (FVC)≥0...
February 15, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29442529/signaling-mediators-modulated-by-cardioprotective-interventions-in-healthy-and-diabetic-myocardium-with-ischaemia-reperfusion-injury
#3
Feyzizadeh Saeid, Javadi Aniseh, Badalzadeh Reza, Vafaee S Manouchehr
Ischaemic heart diseases are one of the major causes of death in the world. In most patients, ischaemic heart disease is coincident with other risk factors such as diabetes. Patients with diabetes are more prone to cardiac ischaemic dysfunctions including ischaemia-reperfusion injury. Ischaemic preconditioning, postconditioning and remote conditionings are reliable interventions to protect the myocardium against ischaemia-reperfusion injuries through activating various signaling pathways and intracellular mediators...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29440185/differing-associations-for-sport-versus-occupational-physical-activity-and-cardiovascular-risk
#4
Marco Mario Ferrario, Mattia Roncaioli, Giovanni Veronesi, Andreas Holtermann, Els Clays, Rossana Borchini, Marco Cavicchiolo, Guido Grassi, Giancarlo Cesana
OBJECTIVES: We investigate the independent and interacting long-term associations of occupational physical activity (OPA) and sport physical activity (SpPA) with the incidence of coronary heart disease (CHD) and cardiovascular diseases (CVD; CHD plus ischaemic stroke) in North Italian male workers. METHODS: 3574 employed men aged 25-64 years, free of CVD at baseline, recruited in three population-based and one factory-based cohorts, were included in the analysis...
February 9, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29436171/ischaemic-heart-disease-following-conventional-and-hypofractionated-radiation-treatment-in-a-contemporary-breast-cancer-series
#5
Melissa James, Sami Swadi, Ma Yi, Lisa Johansson, Bridget Robinson, Ashutosh Dixit
INTRODUCTION: We report the incidence of ischaemic cardiac toxicity in a contemporary cohort of patients receiving conventional (CFRT) or hypofractionated (HFRT) radiation after surgery for early breast cancer and investigate the interplay of cardiac risk factors and fractionation. METHODS: Included were patients receiving external beam radiation treatment from 2002 to 2006 at the Christchurch public hospital. Hospital coding databases, oncology databases and medical records were reviewed for baseline characteristics, treatment details and outcomes...
February 13, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29435772/heart-failure-interventions-targeting-impaired-left-ventricles-in-structural-heart-disease
#6
REVIEW
Mitsunobu Kitamura, Tobias Schmidt, Karl-Heinz Kuck, Christian Frerker
PURPOSE OF REVIEW: Interventional techniques have been developed for a wide spectrum of mechanisms of heart failure (HF), especially in valvular heart disease and cardiomyopathies (ischaemic cardiomyopathy and hypertrophic cardiomyopathy). In this article, we review recent reports on catheter interventions to treat patients with HF. RECENT FINDINGS: Direct modification using the Parachute device and the REVIVENT-TC device for patients with impaired left ventricle with large infarct scars improves geometry and haemodynamic efficiency, resulting in a reduction of HF symptoms...
February 12, 2018: Current Cardiology Reports
https://www.readbyqxmd.com/read/29433517/quality-of-life-of-patients-with-first-time-ami-a-descriptive-study
#7
Mandreker Bahall, Katija Khan
BACKGROUND: Outcomes following acute myocardial infarction (AMI) may result in death, increased morbidity, and change in quality of life (QOL). This study explores health-related QOL of first-time patients following AMI. METHODS: This cross-sectional study used a sample of patients with first-time AMI experienced between April 2011 and March 2015 at a tertiary health institution. Recruited patients belonged to different post-AMI periods: 2-10 weeks, 5-22 months, and > 22 months to 4 years post AMI...
February 13, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29429439/clinical-characteristics-and-causes-of-heart-failure-adherence-to-treatment-guidelines-and-mortality-of-patients-with-acute-heart-failure-experience-at-groote-schuur-hospital-cape-town-south-africa
#8
P Z Szymanski, M Badri, B M Mayosi
BACKGROUND: There is limited information on acute heart failure (AHF) and its treatment in sub-Saharan Africa. OBJECTIVE: To describe the clinical characteristics and causes of heart failure (HF), adherence to HF treatment guidelines, and mortality of patients with AHF presenting to Groote Schuur Hospital (GSH), Cape Town, South Africa. METHODS: This sub-study of The Sub-Saharan Africa Survey of Heart Failure (THESUS-HF) was a prospective and observational survey that focused on the enrolment and follow-up of additional patients with AHF presenting to GSH and entered into the existing registry after publication of the primary THESUS-HF article in 2012...
February 1, 2018: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29422952/gender-differences-in-the-use-of-primary-prevention-icds-in-new-zealand-patients-with-heart-failure
#9
Khang-Li Looi, Karishma Sidhu, Lisa Cooper, Liane Dawson, Debbie Slipper, Andrew Gavin, Nigel Lever
Objective: Women have been under-represented in randomised clinical trials for primary prevention implantable cardioverter defibrillators (ICDs), and there are concerns about the efficacy of devices between genders. Our study aimed to investigate gender differences in the use of primary prevention ICD in patients with heart failure from the northern region of New Zealand. Methods: Patients with heart failure with systolic dysfunction who received primary prevention ICD/cardiac resynchronisation therapy-defibrillator (CRT-D) in the northern region of New Zealand from 1 January 2007 to 1 June 2015 were included...
2018: Heart Asia
https://www.readbyqxmd.com/read/29416204/hemodynamic-responses-to-tracheal-intubation-in-elderly-patients-intravenous-or-spray-of-lidocaine-versus-fentanyl
#10
Alireza Jalali, Ebrahim Nasiri, Mohsen Khoramian, Masood Saghafinia, Hasan Siamian
Introduction: Laryngoscopy and tracheal intubation are known to increase sympathetic activity that may be detrimental to patients with preexisting ischaemic or hypertensive heart disease. Aim: The aim of this study was to compare of intravenous and oropharyngeal spray of lidocaine and high dose of fentanyl on systolic and diastolic blood pressures and heart rate of patients over 65 years during tracheal intubation. Material and Methods: In this clinical trial, 160 patients over 65 yrs who were randomly divided into five groups of 32 patients...
December 2017: Medical Archives
https://www.readbyqxmd.com/read/29415207/progression-of-calcium-density-in-the-ascending-thoracic-aorta-is-inversely-associated-with-incident-cardiovascular-disease-events
#11
Isac C Thomas, Robyn L McClelland, Matthew A Allison, Joachim H Ix, Erin D Michos, Nketi I Forbang, Wendy S Post, Nathan D Wong, Matthew J Budoff, Michael H Criqui
Aims: Little is known regarding the risk of atherosclerotic cardiovascular disease (ASCVD) conferred by changes in the volume and density of ascending thoracic aorta calcium (ATAC) over time. We evaluated changes in ATAC volume and density scores and incident ASCVD events. Methods and results: The Multi-Ethnic Study of Atherosclerosis is a prospective cohort study of individuals without baseline clinical ASCVD. Ascending thoracic aorta calcium was measured from baseline and follow-up (mean interval 2...
February 5, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29395362/methods-to-identify-heart-failure-patients-in-general-practice-and-their-impact-on-patient-characteristics-a-systematic-review
#12
Miek Smeets, Séverine Henrard, Bert Aertgeerts, Filip Cools, Stefan Janssens, Bert Vaes
BACKGROUND: Identifying patients with heart failure (HF) in general practice is challenging. Our aim was to provide an overview of methods used to identify patients with HF in general practice and to assess their impact on patient characteristics. METHODS AND RESULTS: A systematic review was conducted using MEDLINE, EMBASE and CENTRAL. Taken together, 105 studies on HF in general practice were included, totalling 196,105 patients. Five main identification methods for HF were distinguished, including 1) echocardiographic assessments, 2) results of echocardiography in general practitioner (GP) charts, 3) GP judgment after chart review, 4) GP judgment of consecutive patients and 5) only chart review...
January 30, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29394350/blood-pressure-and-cardiovascular-outcomes-in-patients-with-diabetes-and-high-cardiovascular-risk
#13
Brian A Bergmark, Benjamin M Scirica, Ph Gabriel Steg, Christina L Fanola, Yared Gurmu, Ofri Mosenzon, Avivit Cahn, Itamar Raz, Deepak L Bhatt
Aims: Optimal blood pressure for prevention of cardiovascular (CV) events in patients with Type 2 diabetes mellitus (T2DM) remains uncertain and there is concern for increased risk with low diastolic blood pressure (DBP). This study analysed the association between blood pressure and CV outcomes in high-risk patients with T2DM. Methods and results: Patients with T2DM and elevated CV risk were enrolled in the Saxagliptin Assessment of Vascular Outcomes Recorded in patients with diabetes mellitus-Thrombolysis in Myocardial Infarction 53 trial...
January 31, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29393035/long-term-outcome-after-normal-myocardial-perfusion-imaging-in-suspected-ischaemic-heart-disease%C3%A2
#14
Pia Hedegaard Johnsen, Martin Berg Johansen, Svend Eggert Jensen
Ischaemic heart disease (IHD) is the leading cause of mortality in the Western world. Therefore, to focus on those at risk of having IHD while at the same time avoiding unnecessary patient concern, it is important to have diagnostic tools capable of refuting an IHD diagnosis. Within the past 30 years, myocardial perfusion imaging (MPI) has been used increasingly to detect myocardial perfusion defects. MPI is a safe and non-invasive method with a sensitivity and specificity of > 90%. The aim of this study was to evaluate the long-term prognostic outcome after a normal MPI...
February 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29392098/patient-specific-coronary-blood-supply-territories-for-quantitative-perfusion-analysis
#15
Constantine Zakkaroff, John D Biglands, John P Greenwood, Sven Plein, Roger D Boyle, Aleksandra Radjenovic, Derek R Magee
Myocardial perfusion imaging, coupled with quantitative perfusion analysis, provides an important diagnostic tool for the identification of ischaemic heart disease caused by coronary stenoses. The accurate mapping between coronary anatomy and under-perfused areas of the myocardium is important for diagnosis and treatment. However, in the absence of the actual coronary anatomy during the reporting of perfusion images, areas of ischaemia are allocated to a coronary territory based on a population-derived 17-segment (American Heart Association) AHA model of coronary blood supply...
2018: Computer Methods in Biomechanics and Biomedical Engineering. Imaging & Visualization
https://www.readbyqxmd.com/read/29390974/burden-of-ischaemic-heart-disease-and-attributable-risk-factors-in-china-from-1990-to-2015-findings-from-the-global-burden-of-disease-2015-study
#16
Ganshen Zhang, Chuanhua Yu, Maigeng Zhou, Lu Wang, Yunquan Zhang, Lisha Luo
BACKGROUND: Ischaemic heart disease (IHD) is a major barrier to sustainable human development, but its health burden and geographic distribution among provinces of China remain unclear. This study aimed to estimate IHD burden in provinces of China, and attributable to risk factors from 1990 to 2015. METHODS: Data were collected from the Global Burden of Disease 2015 Study, which evaluated IHD burden and attributable risk factors using deaths and disability-adjusted life years (DALYs)...
February 2, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29387460/the-role-of-automated-3d-echocardiography-for-left-ventricular-ejection-fraction-assessment
#17
Ernest Spitzer, Ben Ren, Felix Zijlstra, Nicolas M Van Mieghem, Marcel L Geleijnse
Ejection fraction is one of the most powerful determinants of prognosis and is a crucial parameter for the determination of cardiovascular therapies in conditions such as heart failure, valvular conditions and ischaemic heart disease. Among echocardiographic methods, 3D echocardiography has been attributed as the preferred one for its assessment, given an increased accuracy and reproducibility. Full-volume multi-beat acquisitions are prone to stitching artefacts due to arrhythmias and require prolonged breath holds...
November 2017: Cardiac Failure Review
https://www.readbyqxmd.com/read/29386181/migraine-and-risk-of-cardiovascular-diseases-danish-population-based-matched-cohort-study
#18
Kasper Adelborg, Szimonetta Komjáthiné Szépligeti, Louise Holland-Bill, Vera Ehrenstein, Erzsébet Horváth-Puhó, Victor W Henderson, Henrik Toft Sørensen
OBJECTIVE: To examine the risks of myocardial infarction, stroke (ischaemic and haemorrhagic), peripheral artery disease, venous thromboembolism, atrial fibrillation or atrial flutter, and heart failure in patients with migraine and in a general population comparison cohort. DESIGN: Nationwide, population based cohort study. SETTING: All Danish hospitals and hospital outpatient clinics from 1995 to 2013. PARTICIPANTS: 51 032 patients with migraine and 510 320 people from the general population matched on age, sex, and calendar year...
January 31, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29383860/risk-of-stroke-and-bleeding-in-patients-with-heart-failure-and-chronic-kidney-disease-a-nationwide-cohort-study
#19
Line Melgaard, Thure Filskov Overvad, Flemming Skjøth, Jeppe Hagstrup Christensen, Torben Bjerregaard Larsen, Gregory Y H Lip
AIMS: The aim of this study was to assess the prognostic value of chronic kidney disease (CKD) in relation to ischaemic stroke, intracranial haemorrhage, major bleeding, and all-cause death in heart failure patients without atrial fibrillation. METHODS AND RESULTS: In this observational cohort study, heart failure patients without atrial fibrillation were identified using Danish nationwide registries. Risk of stroke, major haemorrhage, and death were calculated after 1 and 5 years to compare patients with and without CKD, ±dialysis [dialysis: CKD with renal replacement therapy (CKD-RRT); no dialysis: CKD-no RRT]...
January 31, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29378544/cigarette-smoking-and-smoking-attributable-diseases-among-estonian-physicians-a-cross-sectional-study
#20
Mait Raag, Kersti Pärna
BACKGROUND: Smoking is a risk factor for several diseases. Physicians are role models for their patients. Physicians who smoke underestimate the health risks of smoking and may be less likely to offer advice to help their patients to quit. The aim of this study was to: provide an overview of smoking behaviour among Estonian physicians; assess the relationship between smoking and ischaemic heart disease (IHD), chronic bronchitis (CB), and lung emphysema (LE); and estimate fractions of prevalences of the three diseases attributable to smoking...
January 30, 2018: BMC Public Health
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