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https://www.readbyqxmd.com/read/29451672/predictors-of-persistent-prescription-opioid-analgesic-use-among-people-without-cancer-in-australia
#1
Samanta Lalic, Natasa Gisev, J Simon Bell, Maarit Jaana Korhonen, Jenni Ilomäki
AIMS: To identify patterns of opioid analgesic use and determine predictors of persistent opioid use among people without cancer. METHODS: A population-based cohort study of Australians initiating prescription opioids from July 2013 to December 2015 was conducted using data from a random 10% sample of people who accessed medicines through Australia's Pharmaceutical Benefits Scheme. A 12-month look-back period was used to define opioid initiation, exclude people with cancer, and determine comorbidities...
February 16, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29439942/using-robots-at-home-to-support-patients-with-chronic-obstructive-pulmonary-disease-pilot-randomized-controlled-trial
#2
Elizabeth Broadbent, Jeff Garrett, Nicola Jepsen, Vickie Li Ogilvie, Ho Seok Ahn, Hayley Robinson, Kathryn Peri, Ngaire Kerse, Paul Rouse, Avinesh Pillai, Bruce MacDonald
BACKGROUND: Socially assistive robots are being developed for patients to help manage chronic health conditions such as chronic obstructive pulmonary disease (COPD). Adherence to medication and availability of rehabilitation are suboptimal in this patient group, which increases the risk of hospitalization. OBJECTIVE: This pilot study aimed to investigate the effectiveness of a robot delivering telehealth care to increase adherence to medication and home rehabilitation, improve quality of life, and reduce hospital readmission compared with a standard care control group...
February 13, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29433992/changes-in-statin-prescription-patterns-in-patients-admitted-to-an-australian-geriatric-subacute-unit
#3
Samer Noaman, Omar Al-Mukhtar, Sheri Abramovic, Hanin Mohammed, Cheng Yee Goh, Claire Long, Christopher Neil, Edward Janus, Nicholas Cox, William Chan
BACKGROUND: Assessment of demographic and clinical factors influencing the decision of statin discontinuation in the elderly population admitted to subacute geriatric unit. The aim of this study is to assess the clinical factors impacting the decision-making process of statin discontinuation in the elderly. METHODS: We retrospectively assessed changes in statin discontinuation and prescription among patients (≥60 years old) discharged from a geriatric evaluation and management unit by reviewing hospital digital medical records at Western Health - The Williamstown Hospital over a 12-month period from 4 February 2012 until 4 February 2013 inclusive...
January 31, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29419807/barriers-and-facilitators-of-partner-treatment-of-chlamydia-a-qualitative-investigation-with-prescribers-and-community-pharmacists
#4
Helen Wood, Caroline Hall, Emma Ioppolo, Renée Ioppolo, Ella Scacchia, Rhonda Clifford, Sajni Gudka
Chlamydia trachomatis is the most frequently-notified sexually transmitted infection in Australia. Effective and timely partner treatment of chlamydia is essential to reduce overall prevalence and the burden of infection. Currently in most of Australia, the only avenue for partner treatment of chlamydia ("standard partner therapy") is a tedious, and often inconvenient, process. The barriers and facilitators of standard partner therapy, and newer models of accelerated partner therapy (APT), need to be identified in the Australian setting...
February 8, 2018: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29392214/the-opioid-epidemic-and-national-guidelines-for-opioid-therapy-for-chronic-noncancer-pain-a-perspective-from-different-continents
#5
Winfried Häuser, Stephan Schug, Andrea D Furlan
Introduction: A marked rise in opioid prescriptions for patients with chronic noncancer pain (CNCP) with a parallel increase in opioid abuse/misuse, and resulting deaths was noted in the Unites states in the past decade (opioid epidemic). In response, the US Center of Diseases Control (CDC) developed a guideline for prescribing of opioids for patients with CNCP. Objectives: To assess (1) if there is an opioid epidemic in Australia, Canada, and Germany (2) to compare Australian, Canadian, German, and Center of Diseases Control guidelines recommendations for long-term opioid therapy for CNCP...
May 2017: Pain Reports (Baltimore, Md.)
https://www.readbyqxmd.com/read/29387335/contemporary-utilization-of-antithrombotic-therapy-for-stroke-prevention-in-patients-with-atrial-fibrillation-an-audit-in-an-australian-hospital-setting
#6
Ekta Yogeshkumar Pandya, Elizabeth Anderson, Clara Chow, Yishen Wang, Beata Bajorek
Background: To document antithrombotic utilization in patients with nonvalvular atrial fibrillation (NVAF), particularly, recently approved NOACs (nonvitamin K antagonist oral anticoagulants) and warfarin; and identify factors predicting the use of NOACs versus warfarin. Methods: A retrospective audit was conducted in an Australian hospital. Data pertaining to inpatients diagnosed with atrial fibrillation (AF) admitted between January and December 2014 were extracted...
February 2018: Therapeutic Advances in Drug Safety
https://www.readbyqxmd.com/read/29386279/prescription-of-antihypertensive-medication-at-discharge-influences-survival-following-stroke
#7
Nadine E Andrew, Joosup Kim, Amanda G Thrift, Monique F Kilkenny, Natasha A Lannin, Craig S Anderson, Geoffrey A Donnan, Kelvin Hill, Sandy Middleton, Christopher Levi, Steven Faux, Rohan Grimley, Nisal Gange, Richard Geraghty, Sharan Ermel, Dominique A Cadilhac
OBJECTIVE: To investigate the risk of death from cardiovascular disease between patients who were and were not prescribed antihypertensive medication following stroke or TIA. METHODS: This was a large cohort study using routinely collected prospective data from the Australian Stroke Clinical Registry. Patients registered between 2009 and 2013 who were discharged to the community or rehabilitation were included. Cases were linked to the National Death Index to determine the date and cause of death...
January 31, 2018: Neurology
https://www.readbyqxmd.com/read/29374472/exploring-health-care-seeking-knowledge-perceptions-and-practices-for-childhood-diarrhea-and-pneumonia-and-their-context-in-a-rural-pakistani-community
#8
Wafa Aftab, Leah Shipton, Fauziah Rabbani, Kashif Sangrasi, Shagufta Perveen, Aysha Zahidie, Imran Naeem, Shamim Qazi
BACKGROUND: Where access to facilities for childhood diarrhea and pneumonia is inadequate, community case management (CCM) is an effective way of improving access to care. In Pakistan, utilization of CCM for these diseases through the Lady Health Worker Program remains low. Challenges of access to facilities persist leading to delayed care and poor outcomes. Estimating caregiver knowledge, understanding their perceptions and practices, and recognizing how these are related to care seeking decisions about childhood diarrhea and pneumonia is crucial to bring about coherence between supply and demand-side practices...
January 27, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29372070/a-feasibility-study-of-a-randomised-controlled-trial-to-examine-the-impact-of-the-abcde-bundle-on-quality-of-life-in-icu-survivors
#9
Kellie Sosnowski, Marion L Mitchell, Hayden White, Lynette Morrison, Joanne Sutton, Jessica Sharratt, Frances Lin
Background: Early rehabilitation has been found to prevent delirium and weakness that can hamper the recovery of intensive care unit (ICU) survivors. Integrated clinical practice guidelines for managing patient pain, agitation and delirium (PAD) have been developed. The Awakening and Breathing Coordination, Delirium monitoring/management, and Early exercise/mobility (ABCDE) bundle provides a strategy to implement PAD guidelines into everyday clinical practice. However, there is limited evidence on the effectiveness of the ABCDE bundle in the literature...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29371890/diabetic-foot-australia-guideline-on-footwear-for-people-with-diabetes
#10
Jaap J van Netten, Peter A Lazzarini, David G Armstrong, Sicco A Bus, Robert Fitridge, Keith Harding, Ewan Kinnear, Matthew Malone, Hylton B Menz, Byron M Perrin, Klaas Postema, Jenny Prentice, Karl-Heinz Schott, Paul R Wraight
Background: The aim of this paper was to create an updated Australian guideline on footwear for people with diabetes. Methods: We reviewed new footwear publications, (inter)national guidelines, and consensus expert opinion alongside the 2013 Australian footwear guideline to formulate updated recommendations. Result: We recommend health professionals managing people with diabetes should: (1) Advise people with diabetes to wear footwear that fits, protects and accommodates the shape of their feet...
2018: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29347932/epidemiology-of-arthritis-chronic-back-pain-gout-osteoporosis-spondyloarthropathies-and-rheumatoid-arthritis-among-1-5-million-patients-in-australian-general-practice-nps-medicinewise-medicineinsight-dataset
#11
David Alejandro González-Chica, Simon Vanlint, Elizabeth Hoon, Nigel Stocks
BACKGROUND: Previous estimates for the prevalence of musculoskeletal conditions (MSK) and chronic pain in Australia have been based on self-report. We aimed to determine the prevalence and distribution of arthritis, chronic back pain, gout, osteoporosis, spondyloarthropathies and rheumatoid arthritis and current consultations for chronic pain among adults attending Australian general practice, and describe their distribution according to sociodemographic characteristics and presence of co-morbidities...
January 18, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29332434/relationship-between-antimicrobial-resistance-programs-and-antibiotic-dispensing-for-upper-respiratory-tract-infection-an-analysis-of-australian-data-between-2004-and-2015
#12
Jianyun Wu, Daniel Taylor, Ludmila Ovchinikova, Aine Heaney, Tessa Morgan, Jonathan Dartnell, Rachel Holbrook, Lauren Humphreys, Lynn Weekes, Suzanne Blogg
Objective NPS MedicineWise aims to ensure that medicines are prescribed and used in a manner consistent with current evidence-based best practice. A series of nationwide educational and advertising interventions for general practitioners and consumers were implemented in Australia between 2009 and 2015 with the aim of reducing antibiotic prescriptions for upper respiratory tract infections (URTIs). The work described in this paper quantifies the change in antibiotic dispensing following these interventions...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29330715/case-series-analysis-of-new-zealand-reports-of-rapid-intense-potentiation-of-warfarin-by-roxithromycin
#13
Ruth L Savage, Michael V Tatley
INTRODUCTION: We undertook an analysis of all the reports to the New Zealand Centre for Adverse Reactions Monitoring of a roxithromycin/warfarin interaction after two recent reports described intense rapid warfarin potentiation. The interaction was first published in 1995. Cytochrome P450 3A4 inhibition has been the proposed mechanism but has limited biologic plausibility. There are suggestions that the clinical significance of the interaction may be increased by severe illness, polypharmacy, renal dysfunction, older age and increased warfarin sensitivity...
January 12, 2018: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/29329559/simplification-of-medications-prescribed-to-long-term-care-residents-simpler-study-protocol-for-a-cluster-randomised-controlled-trial
#14
Janet K Sluggett, Esa Y H Chen, Jenni Ilomäki, Megan Corlis, Sarah N Hilmer, Jan Van Emden, Choon Ean Ooi, Kim-Huong Nguyen, Tracy Comans, Michelle Hogan, Tessa Caporale, Susan Edwards, Lyntara Quirke, Allan Patching, J Simon Bell
BACKGROUND: Complex medication regimens are highly prevalent in residential aged care facilities (RACFs). Strategies to reduce unnecessary complexity may be valuable because complex medication regimens can be burdensome for residents and are costly in terms of nursing time. The aim of this study is to investigate application of a structured process to simplify medication administration in RACFs. METHODS: SImplification of Medications Prescribed to Long-tErm care Residents (SIMPLER) is a non-blinded, matched-pair, cluster randomised controlled trial of a single multidisciplinary intervention to simplify medication regimens...
January 12, 2018: Trials
https://www.readbyqxmd.com/read/29320660/nicotine-replacement-therapy-for-smoking-cessation-during-pregnancy
#15
Yael Bar-Zeev, Ling Li Lim, Billie Bonevski, Maree Gruppetta, Gillian S Gould
Nicotine replacement therapy (NRT) is recommended in current Australian clinical guidelines for pregnant women who are unable to quit smoking unassisted. Clinicians report low levels of prescribing NRT during pregnancy, due to safety concerns and low levels of confidence in their ability to prescribe NRT. Animal models show that nicotine is harmful to the fetus, especially for brain and lung development, but human studies have not found any harmful effects on fetal and pregnancy outcomes. Studies of efficacy and effectiveness in the real world suggest that NRT use during pregnancy increases smoking cessation rates...
January 15, 2018: Medical Journal of Australia
https://www.readbyqxmd.com/read/29317112/cannabinoid-disposition-after-human-intraperitoneal-use-an-insight-into-intraperitoneal-pharmacokinetic-properties-in-metastatic-cancer
#16
Catherine J Lucas, Peter Galettis, Shuzhen Song, Nadia Solowij, Stephanie E Reuter, Jennifer Schneider, Jennifer H Martin
BACKGROUND: Medicinal cannabis is prescribed under the provision of a controlled drug in the Australian Poisons Standard. However, multiple laws must be navigated in order for patients to obtain access and imported products can be expensive. Dose-response information for both efficacy and toxicity pertaining to medicinal cannabis is lacking. The pharmacokinetic properties of cannabis administered by traditional routes has been described but to date, there is no literature on the pharmacokinetic properties of an intraperitoneal cannabinoid emulsion...
January 6, 2018: Clinical Therapeutics
https://www.readbyqxmd.com/read/29314552/australian-multicentre-study-of-current-real-world-prophylaxis-practice-in-severe-and-moderate-haemophilia-a-and-b
#17
J A Mason, S Parikh, H Tran, J Rowell, S McRae
INTRODUCTION: With the emergence of novel treatment products for haemophilia and an increasing focus on the benefits of pharmacokinetic driven individualized prophylaxis, robust national data with regard to current patterns of factor consumption and adherence are required. AIM: To characterize current Australian practice with regard to use of prophylactic clotting factor infusions in patients with moderate or severe haemophilia A (HA) and haemophilia B (HB). METHODS: This was a retrospective, non-interventional study utilizing Australian Bleeding Disorder Registry (ABDR) data collected over a 12 month period...
January 3, 2018: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/29314054/evidence-based-practice-guidelines-for-prescribing-home-modifications-for-clients-with-bariatric-care-needs
#18
Laura de Lange, Emma Coyle, Helen Todd, Cylie Williams
BACKGROUND/AIM: Home modifications maintain people's functional independence and safety. No literature exists to guide the prescription of home modifications for clients with bariatric care needs. With Australia's increasing obesity rate, more evidence is needed to support home modification prescribers. This study aimed to map Australian home modification prescribing practices for clients with bariatric care needs and to establish and evaluate a clinical resource for this prescription process...
January 5, 2018: Australian Occupational Therapy Journal
https://www.readbyqxmd.com/read/29300863/changes-in-orchid-populations-and-endophytic-fungi-with-rainfall-and-prescribed-burning-in-pterostylis-revoluta-in-victoria-australia
#19
N U Jasinge, T Huynh, A C Lawrie
Background and Aims: Wildfires are common in seasonally dry parts of the world with a Mediterranean climate. Prescribed burning is used to reduce fuel load and fire risk, but often without reliable information on its effects. This study investigated the effects of prescribed burns in different seasons on Pterostylis revoluta, an autumn-flowering Australian terrestrial orchid, and its orchid mycorrhizal fungi (OMFs) to find the least damaging season for a prescribed burn. Methods: Burns were conducted mid-season in spring and summer 2011 and autumn and winter 2012...
January 2, 2018: Annals of Botany
https://www.readbyqxmd.com/read/29284446/management-of-whiplash-associated-disorders-in-australian-general-practice
#20
Jane Nikles, Michael Yelland, Clare Bayram, Graeme Miller, Michele Sterling
BACKGROUND: Whiplash Associated Disorders (WAD) are common and costly, and are usually managed initially by general practitioners (GPs). How GPs manage WAD is largely unstudied, though there are clinical guidelines. Our aim was to ascertain the rate of management (percentage of encounters) of WAD among patients attending Australian general practice, and to review management of these problems, including imaging, medications and other treatments. METHODS: We analysed data from 2013 to 2016 collected by different random samples of approximately 1000 general practitioners (GPs) per year...
December 29, 2017: BMC Musculoskeletal Disorders
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