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https://www.readbyqxmd.com/read/29770362/study-of-anti-m%C3%A3-llerian-hormone-levels-in-patients-with-myotonic-dystrophy-type-1-preliminary-results
#1
Manuela Ergoli, Massimo Venditti, Raffaele Dotolo, Esther Picillo, Sergio Minucci, Luisa Politano
Myotonic dystrophy type 1 is a multisystemic disorder characterized by myotonia, muscle weakness and involvement of several organs and apparatus such as heart, lungs, eye, brain and endocrine system. Hypogonadism and reproductive abnormalities are frequently reported. A progressive testicular atrophy occurs in about 80% in the affected males leading to Leydig cell hyperproliferation and elevated basal follicle stimulating hormone (FSH) levels. Anti-Müllerian hormone (AMH) - a dimeric glycoprotein belonging to the super-family of transforming grow factor beta (TGF-beta) - is the earliest Sertoli cell hormone secreted in males and, together with inhibin B and FSH, is an important indicator of Sertoli cell function...
December 2017: Acta Myologica: Myopathies and Cardiomyopathies: Official Journal of the Mediterranean Society of Myology
https://www.readbyqxmd.com/read/29765438/decline-in-ovarian-reserve-may-be-an-undiagnosed-reason-for-unexplained-infertility-a-cohort-study
#2
Burak Yücel, Sefa Kelekci, Emine Demirel
Introduction: Unexplained infertility refers to the absence of a definable cause for a couple's failure to achieve pregnancy. Reproductive aging plays a role in pathogenesis of unexplained infertility. We investigated the results of ovarian reserve tests in unexplained infertility. Material and methods: The patients were divided into two groups: unexplained infertility ( n = 148) and male factor infertility ( n = 112). Follicle-stimulating hormone, estradiol, inhibin b levels and anti-Müllerian hormone levels were evaluated...
April 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29753148/sex-related-differences-in-the-associations-between-maternal-dioxin-like-compounds-and-reproductive-and-steroid-hormones-in-cord-blood-the-hokkaido-study
#3
Chihiro Miyashita, Atsuko Araki, Takahiko Mitsui, Sachiko Itoh, Houman Goudarzi, Seiko Sasaki, Jumboku Kajiwara, Tsuguhide Hori, Kazutoshi Cho, Kimihiko Moriya, Nobuo Shinohara, Katsuya Nonomura, Reiko Kishi
BACKGROUND: Prenatal exposure to dioxin-like compounds (DLCs) irreversibly affects fetal reproductive and steroid hormone synthesis. OBJECTIVE: This study aimed to assess the relationships between maternal DLCs and cord blood reproductive and steroid hormones. METHODS: Participants in this study were pregnant women who enrolled in the Sapporo Cohort of the Hokkaido Study between 2002 and 2005. We quantified 29 DLCs during the 2nd and 3rd trimesters in maternal blood...
May 9, 2018: Environment International
https://www.readbyqxmd.com/read/29752954/regulation-of-the-activins-follistatins-inhibins-axis-by-energy-status-impact-on-reproductive-function
#4
Nikolaos Perakakis, Jagriti Upadhyay, Wael Ghaly, Joyce Chen, Pavlina Chrysafi, Athanasios D Anastasilakis, Christos S Mantzoros
BACKGROUND: We have previously demonstrated that the adipose tissue derived hormone leptin controls reproductive function by regulating the hypothalamic-pituitary-gonadal axis in response to energy deficiency. Here, we evaluate the activins-follistatins-inhibins (AFI) axis during acute (short-term fasting in healthy people) and chronic energy deficiency (women with hypothalamic amenorrhea due to strenuous exercise [HA]) and investigate their relation to leptin and reproductive function in healthy subjects and subjects with HA...
May 9, 2018: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29740842/melatonin-therapy-adds-extra-benefit-to-varicecelectomy-in-terms-of-sperm-parameters-hormonal-profile-and-total-antioxidant-capacity-a-placebo-controlled-double-blind-trial
#5
X-L Lu, J-J Liu, J-T Li, Q-A Yang, J-M Zhang
In this study, we aimed at investigating the impact of melatonin supplementation on semen parameters, hormonal profile and total antioxidant capacity after varicocelectomy. Infertile male patients who were diagnosed with varicocele and underwent subinguinal varicocelectomy were included in the study. After performing subinguinal varicocelectomy, the patients were randomised into two groups: 27 receiving melatonin for 3 months and 27 as the placebo-controlled group receiving placebo for 3 months. The pre-operative parameters of semen analyses, hormonal profile and seminal oxidative stress status of both groups were compared with those of post-operative parameters...
May 8, 2018: Andrologia
https://www.readbyqxmd.com/read/29738413/is-ovarian-reserve-associated-with-body-mass-index-and-obesity-in-reproductive-aged-women-a-meta-analysis
#6
Nazanin Moslehi, Sakineh Shab-Bidar, Fahimeh Ramezani Tehrani, Parvin Mirmiran, Fereidoun Azizi
OBJECTIVE: The associations of body mass index (BMI) and obesity with ovarian reserve are controversial. This systematic review and meta-analysis was conducted to investigate the associations in reproductive-aged women. METHODS: PubMed and Scopus were searched up to December, 2016. Original studies on the association of BMI with ovarian reserve markers, anti-Mullerian hormone (AMH), follicle-stimulating hormone (FSH), inhibin β, and antral follicle count (AFC), either according to BMI categories or a continuous variable, were selected...
May 7, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29738164/-seminal-plasma-anti-m%C3%A3-llerian-hormone-and-inhibin-b-and-serum-inhibin-b-in-predicting-the-outcome-of-routine-ivf-fertilization
#7
Yan-Fei Wang, Xin Wu, Rong Hu, Fei-Miao Wang, Shao-Tong Jia, Li-Guo Pei, Hui Wang, Xiao-E Ouyang, Ting Hu, Yun-Xing Fu
Objective: To analyze the correlations of seminal plasma (sp) anti-Müllerian hormone (spAMH) and inhibin B (spINHB) and serum INHB (serINHB) with semen parameters in oligoasthenospermia patients and explore their value in predicting the outcome of routine in vitro fertilization (IVF). METHODS: We obtained the levels of spAMH, spINHB and serINHB as well as semen parameters from 88 infertile males undergoing IVF due to oligoasthenospermia or female uterine tubal factors from August 2016 to February 2017...
November 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29734187/novel-serum-biomarkers-detected-by-protein-array-in-polycystic-ovary-syndrome-with-low-progesterone-level
#8
Qin Zheng, Feifei Zhou, Xinyuan Cui, Mulin Liu, Yulin Li, Shuai Liu, Jichun Tan, Qiu Yan
BACKGROUND/AIMS: Polycystic ovary syndrome (PCOS), characterized by female infertility and metabolic abnormalities, is one of the most common endocrine disorders. The etiology of PCOS remains unknown. The comprehensive analysis of protein alterations in PCOS patients is meaningful for identifying diagnostic biomarkers of PCOS. Here, we explored the clinical value of serum proteins as novel biomarkers to detect PCOS with low progesterone level. METHODS: A total of 43 patients with PCOS and 30 healthy women were enrolled...
May 3, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29731629/nanosized-titanium-dioxide-induced-premature-ovarian-failure-is-associated-with-abnormalities-in-serum-parameters-in-female-mice
#9
Fashui Hong, Ling Wang
Background: Exposure to titanium dioxide nanoparticles (TiO2 NPs) that are widely used in food, medicine, sunscreen products and cosmetics is reported to cause ovarian damage and lower fertility in animals. However, the potential effects of TiO2 NPs application on premature ovarian failure (POF) have rarely been evaluated to date. Methods: In this study, female mice were continuously exposed to TiO2 NPs at doses of 2.5, 5 or 10 mg/kg via gavage instillation for 30 days, and investigated the serum hormones and autoimmunity markers associated with POF...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29726646/-orchidopexy-increases-the-levels-of-serum-anti-m%C3%A3-llerian-hormone-and-inhibin-b-in-cryptorchidism-patients
#10
Shun-Shun Cao, Yang-Yang Hu, Cun-Jin Nan
Objective: To investigate the levels of serum anti-Müllerian hormone (AMH) and inhibin B (INHB) in patients with unilateral cryptorchidism before and after orchidopexy. METHODS: This study included 58 cases of unilateral cryptorchidism treated by orchidopexy and 32 healthy controls. Before and at 6 months after surgery, we measured the length and circumference of the penis, the volume of the undescended testis, and levels of serum AMH and INHB. RESULTS: There were statistically significant differences between the unilateral cryptorchidism and healthy control groups in the levels of serum AMH ([102...
August 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29725281/ovarian-reserve-evaluation-after-laparoscopic-cyst-enucleation-depending-on-applied-haemostasis-technique-and-with-particular-consideration-of-endometrial-cysts
#11
Dariusz Owczarek, Andrzej Malinowski, Miłosz Wilczyński
Aim of the study: was an evaluation of the effects, exerted by obtained haemostasis on ovarian reserve, depending on haemostasis technique, applied after laparoscopic enucleation of endometrial cysts. Material and methods: Sixty-six female patients, at the age of 20-35 years, were included into the study. The diameters of the cystic lesions were within 40-70 mm. The patients were randomly assigned to two study groups. Group 1 involved patients after laparoscopic enucleation of ovarian cysts, in whom haemostasis was achieved by ovary suturing, while Group 2 included patients with haemostasis achieved by bipolar coagulation technique...
March 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/29723455/-impacts-of-different-procedures-of-testicular-sperm-retrieval-on-testicular-function-and-antisperm-antibodies-in-azoospermia-patients
#12
Yang-Yang Hu, Li-Yuan Wang, Bo-Tian Song, Shun-Shun Cao, Ao-Lei Chen
Objective: To investigate the influence of different procedures of testicular sperm retrieval on the levels of serum inhibin B (INHB), antisperm antibodies (AsAb), follicle-stimulating hormone (FSH), and testosterone (T) in patients with azoospermia. METHODS: We randomly assigned 210 azoospermia patients to receive testicular sperm extraction (TESE, n = 50), testicular sperm aspiration (TESA, n = 56), testicular fine needle aspiration (TEFNA, n = 64), or microscopic TESE (micro-TESE, n = 40)...
July 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29722946/-correlation-of-serum-anti-m%C3%A3-llerian-hormone-with-semen-parameters
#13
Long-Ping Peng, Yong Shao, Cen-Cen Wang, Zhi-Chuan Zou, Tao Shen, Li Chen, Bing Yao
Objective: To investigate the relationship between the serum anti-Müllerian hormone (AMH) level and semen parameters. METHODS: We collected the data about 726 outpatients at the Male Infertility Clinic of Jinling Hospital from September 2015 to November 2016, including 72 with non-obstructive azoospermia, 123 with oligospermia, and 531 with normal sperm concentration. We obtained the semen volume, total sperm count, sperm concentration, sperm motility, the percentages of progressively motile sperm (PMS) and morphologically normal sperm (MNS), and the levels of serum AMH, inhibin B (INH-B), total testosterone (TT) and follicle - stimulating hormone (FSH) of the patients, analyzed the correlation of the serum AMH level with the other parameters, and compared the AMH level among different groups...
June 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29706444/impaired-serum-inhibin-b-and-number-of-germ-cells-in-boys-with-cryptorchidism-following-heavily-gestational-maternal-smoking
#14
Simone Hildorf, Erik Clasen-Linde, Lihua Dong, Dina Cortes, Jorgen Thorup
PURPOSE: A meta-analysis including 11,900 cases showed that maternal gestational smoking was associated with increased risk of cryptorchidism. The aim of study was to investigate whether a hormone profile of cryptorchid boys and a supplementing histopathological evaluation of testicular biopsies could add detailed knowledge to the impact of maternal gestational smoking on pathogenesis of cryptorchidism. METHODS: 601 cryptorchid boys aged 4 months to 14 years old were included...
April 5, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29705715/solid-pseudopapillary-neoplasm-spn-of-the-testis-comprehensive-mutational-analysis-of-6-testicular-and-8-pancreatic-spns
#15
Kvetoslava Michalova, Michael Michal, Monika Sedivcova, Dmitry V Kazakov, Carlos Bacchi, Tatjana Antic, Marketa Miesbauerova, Ondrej Hes, Michal Michal
BACKGROUND: Recently, we came with the theory of a possible relationship between a group of testicular and pancreatic tumors. We used one case of a pancreatic analogue solid pseudopapillary neoplasm of the testis composed partially of areas reminiscent of solid pseudopapillary neoplasm (SPN) of the pancreas and partially of structures identical to primary signet ring stromal tumor of the testis (PSRSTT) as a connecting link between these two entities. After demonstrating that PSRSTT and pancreatic analogue SPN of the testis share the same immunoprofile and genetic features characteristic for pancreatic SPN, we came to the conclusion that pancreatic analogue SPN of the testis and PSRSTT represent a morphological spectrum of a single entity and that both are related to the pancreatic SPN...
April 20, 2018: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/29704537/testosterone-and-fsh-modulate-sertoli-cell-extracellular-secretion-proteomic-analysis
#16
Francesca Mancuso, Mario Calvitti, Domenico Milardi, Giuseppe Grande, Giulia Falabella, Iva Arato, Stefano Giovagnoli, Federica Vincenzoni, Francesca Mancini, Claudio Nastruzzi, Maria Bodo, Tiziano Baroni, Massimo Castagnola, Riccardo Marana, Alfredo Pontecorvi, Riccardo Calafiore, Giovanni Luca
Spermatogenesis is a highly complicated biological process that occurs in the epithelium of the seminiferous tubules. It is regulated by a complex network of endocrine and paracrine factors and by juxtacrine testicular cross-talk. Sertoli cells (SC) play a key role in spermatogenesis due to their production of trophic, differentiation and immune-modulating factors, but many of the molecular pathways of SC action remain controversial and unclear. Over the last two decades, research has focused on extracellular vesicles as an important mechanism of intercellular communication...
April 25, 2018: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/29696926/-protective-effects-of-electroacupuncture-pretreatment-on-ovarian-in-rats-with-premature-ovarian-insufficiency
#17
Weiming Wang, Yang Wang, Jiani Wu, Likun Yang, Zhishun Liu
OBJECTIVE: To explore the protective effect and possible mechanism of electroacupuncture (EA) pretreatment at "Zhongliao" (BL 33) and "Tianshu" (ST 25) on ovarian in rats with premature ovarian insufficiency (POI). METHODS: A total of 32 SD female rats with regular estrus were randomly divided into a blank group, a model group, an EA group and an immobilization group, 8 rats in each one. The rats in the model group, EA group and immobilization group were treated with intraperitoneal injection of 4-vinylcyclohexene diepoxide (160 mg/kg) for 15 days to establish the model...
April 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29668033/sexual-dimorphism-in-postnatal-gonadotropin-levels-in-infancy-reflects-diverse-maturation-of-the-ovarian-and-testicular-hormone-synthesis
#18
Tanja Kuiri-Hänninen, Leo Dunkel, Ulla Sankilampi
BACKGROUND: The postnatal gonadotropin surge is sexually dimorphic: FSH levels predominate in girls and LH levels in boys. However, in preterm (PT) girls, both gonadotropin levels are higher than in PT boys. OBJECTIVE: To evaluate how gonadal maturation contributes to the sex differences in FSH and LH. DESIGN: Monthly follow-up of 58 full-term (FT, 29 boys) and 67 PT (33 boys) infants from one week (D7) to six months of age (M1-M6). Analyses were also done according to postmenstrual (PM) age in PT infants...
April 18, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29661120/uterine-tumors-resembling-ovarian-sex-cord-tumors-in-four-baboons-papio-spp
#19
Sara Mangosing, Ekaterina Perminov, Olga Gonzalez, Erica K Barkei, Emily M Corbin, Shyamesh Kumar, Edward J Dick
Uterine tumors resembling ovarian sex cord tumors (UTROSCTs) are rare uterine neoplasms that exhibit prominent sex cord-like differentiation. The authors describe 4 cases of UTROSCTs that were identified as incidental lesions in female baboons. All baboons were in good body condition. One animal had a 2-mm-diameter yellow-tan mass in the uterine body along the attachment of the left broad ligament; the other 3 did not have any gross lesions in the uterus. Histologically, the myometrium contained multifocal well-demarcated neoplasms composed of cuboidal to columnar cells arranged in variable arrangements of sheets, nests, cords, trabecular, and retiform patterns that occasionally formed Call-Exner-like bodies...
January 1, 2018: Veterinary Pathology
https://www.readbyqxmd.com/read/29658438/a-systematic-review-of-first-trimester-biochemical-and-molecular-predictive-tests-for-preeclampsia
#20
Fatemeh Abdi, Zohreh Aghaie, Fatemeh Sadat Rahnemaie, Zainab Alimoradi
BACKGROUND: Preeclampsia is a multisystem disorder affecting 5%-8% of pregnant women. Considering the ongoing debate over the predicting value of some commercial first trimester tests, the aim of this study was to compare the existing first trimester screening tests for preeclampsia. METHODS: In this systematic review, relevant articles published during 2000-2017 were extracted from PubMed, Science Direct, Scopus, Cochrane Library, ISI Web of Science, and ProQuest databases...
April 16, 2018: Current Hypertension Reviews
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