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Dietary protein

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https://www.readbyqxmd.com/read/28102354/a-signature-of-renal-stress-resistance-induced-by-short-term-dietary-restriction-fasting-and-protein-restriction
#1
F Jongbloed, T C Saat, M Verweij, C Payan-Gomez, J H J Hoeijmakers, S van den Engel, C T van Oostrom, G Ambagtsheer, S Imholz, J L A Pennings, H van Steeg, J N M IJzermans, M E T Dollé, R W F de Bruin
During kidney transplantation, ischemia-reperfusion injury (IRI) induces oxidative stress. Short-term preoperative 30% dietary restriction (DR) and 3-day fasting protect against renal IRI. We investigated the contribution of macronutrients to this protection on both phenotypical and transcriptional levels. Male C57BL/6 mice were fed control food ad libitum, underwent two weeks of 30%DR, 3-day fasting, or received a protein-, carbohydrate- or fat-free diet for various periods of time. After completion of each diet, renal gene expression was investigated using microarrays...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28102299/systemic-regulation-of-l-carnitine-in-nutritional-metabolism-in-zebrafish-danio-rerio
#2
Jia-Min Li, Ling-Yu Li, Xun Qin, Li-Jun Ning, Dong-Liang Lu, Dong-Liang Li, Mei-Ling Zhang, Xin Wang, Zhen-Yu Du
Excess fat accumulation has been observed widely in farmed fish; therefore, efficient lipid-lowering factors have obtained high attention in the current fish nutrition studies. Dietary L-carnitine can increase fatty acid β-oxidation in mammals, but has produced contradictory results in different fish species. To date, the mechanisms of metabolic regulation of L-carnitine in fish have not been fully determined. The present study used zebrafish to investigate the systemic regulation of nutrient metabolism by dietary L-carnitine supplementation...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28101967/host-related-factors-explaining-interindividual-variability-of-carotenoid-bioavailability-and-tissue-concentrations-in-humans
#3
Torsten Bohn, Charles Desmarchelier, Lars O Dragsted, Charlotte S Nielsen, Wilhelm Stahl, Ralph Rühl, Jaap Keijer, Patrick Borel
Carotenoid dietary intake and their endogenous levels have been associated with a decreased risk of several chronic diseases. There are indications that carotenoid bioavailability depends, in addition to the food matrix, on host factors. These include diseases (e.g. colitis), life-style habits (e.g. smoking), gender and age, as well as genetic variations including single nucleotide polymorphisms that govern carotenoid metabolism. These are expected to explain interindividual differences that contribute to carotenoid uptake, distribution, metabolism and excretion, and therefore possibly also their association with disease risk...
January 19, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28101772/zinc-deficiency-in-the-pediatric-age-group-is-common-but-underevaluated
#4
Dogus Vuralli, Leyla Tumer, Alev Hasanoglu
BACKGROUND: Subclinical micronutrient deficiencies have been gradually becoming more important as a public health problem and drawing attention of the health authorities. Today it has been known that detecting and treating people having deficiency symptoms alone is no longer sufficient. It is important to detect and prevent any deficiency before it displays clinical manifestations. Zinc deficiency is one of the most widespread micronutrient deficiencies. In this study, we aimed to evaluate the zinc status and the associated factors in healthy school-age children...
January 19, 2017: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/28101704/molecular-cloning-and-gene-protein-expression-of-fat-cd36-from-grass-carp-ctenopharyngodon-idella-and-the-regulation-of-its-expression-by-dietary-energy
#5
Juan Tian, Wei Liu, Weihua Gao, Fan Wu, Lijuan Yu, Xing Lu, Chang-Geng Yang, Ming Jiang, Hua Wen
Fatty acid translocase/cluster of differentiation 36 (FAT/CD36) functions as a membrane long-chain fatty acid transporter in various tissues in land animals. Not much is known about the CD36 molecule in teleost fish. Therefore, we studied CD36 in grass carp (Ctenopharyngodon idella, ciCD36). The full-length complementary DNA sequence of ciCD36 was 1976 bp, with an ORF of 468 amino acids, which had high sequence similarity to the CD36 of common carp. The messenger RNA (mRNA) expression of ciCD36 was high in the intestine, heart, liver, visceral tissue, and brain, but absent in the kidney...
January 18, 2017: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/28100883/soy-protein-isolate-suppresses-lipodystrophy-induced-hepatic-lipid-accumulation-in-model-mice
#6
Koji Nagao, Akiko Matsumoto, Shunichi Kai, Tomoko Kayashima, Teruyoshi Yanagita
Lipodystrophies are acquired and genetic disorders characterized by the complete or partial absence of body fat with a line of metabolic disorders, including hepatic steatosis. Because soy protein isolate (SPI) has been reported to reduce cholesterol and triglyceride levels in animals and humans, we explored the effect of SPI on the pathophysiology of hepatic lipid accumutaion in a diet-induced lipodystrophy model mice. Four weeks of the lipodystrophy model diet induced hepatic lipid accumulation concomitant with marked deficiencies of adipose tissue and serum adipocytokines in mice...
January 18, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28100844/phospholipids-and-products-of-their-hydrolysis-as-dietary-preventive-factors-for-civilization-diseases
#7
Karol Parchem, Agnieszka Bartoszek
The results of numerous epidemiological studies indicate that phospholipids play an important role in the prevention of chronic diseases faced by contemporary society. Firstly, these compounds are responsible for the proper functioning of cell membranes, by ensuring liquidity and permeability, which is pivotal for normal activity of membrane proteins, including receptors. These mechanisms are at the core of prevention of cancer, autoimmune or neurological disorders. Secondly, structure and properties of phospholipids cause that they are highly available source of biologically active fatty acids...
December 31, 2016: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/28100325/-an-investigation-of-dietary-nutrition-in-kindergartens-of-chongqing-china
#8
Xia Liu, Xin Fan
OBJECTIVE: To investigate the status of dietary nutrition in kindergartens of Chongqing, China. METHODS: A total of 295 kindergartens (47 first-class ones, 88 second-class ones, and 160 third-class ones) from the 11 districts or counties of Chongqing by stratified cluster random sampling were investigated. The dietary nutrition in each kindergarten was evaluated by weighing. The dietary qualification rates were compared between the three classes of kindergartens...
January 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28100190/translation-of-a-tailored-nutrition-and-resistance-exercise-intervention-for-elderly-people-to-a-real-life-setting-adaptation-process-and-pilot-study
#9
Ellen Ji van Dongen, Joanne N Leerlooijer, Jan M Steijns, Michael Tieland, Lisette Cpgm de Groot, Annemien Haveman-Nies
BACKGROUND: Combining increased dietary protein intake and resistance exercise training for elderly people is a promising strategy to prevent or counteract the loss of muscle mass and decrease the risk of disabilities. Using findings from controlled interventions in a real-life setting requires adaptations to the intervention and working procedures of healthcare professionals (HCPs). The aim of this study is to adapt an efficacious intervention for elderly people to a real-life setting (phase one) and test the feasibility and potential impact of this prototype intervention in practice in a pilot study (phase two)...
January 18, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28099989/effects-of-a-dietary-ketone-ester-on-hippocampal-glycolytic-and-tca-cycle-intermediates-and-amino-acids-in-a-3xtgad-mouse-model-of-alzheimer-s-disease
#10
Robert J Pawlosky, Martin F Kemper, Yoshihero Kashiwaya, M Todd King, Mark P Mattson, Richard L Veech
In patients with Alzheimer's disease (AD) and in a triple transgenic (3xTgAD) mouse model of AD low glucose metabolism in the brain precedes loss of memory and cognitive decline. The metabolism of ketones in the brain by-passes glycolysis and therefore may correct several deficiencies that are associated with glucose hypometabolism. A dietary supplement composed of an ester of D-β-hydroxybutyrate and R-1,3 butane diol referred to as ketone ester (KE) was incorporated into a rodent diet and fed to 3xTgAD mice for 8 months...
January 18, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28099509/a-comparative-study-on-antioxidant-system-in-fish-hepatopancreas-and-intestine-affected-by-choline-deficiency-different-change-patterns-of-varied-antioxidant-enzyme-genes-and-nrf2-signaling-factors
#11
Pei Wu, Yang Liu, Wei-Dan Jiang, Jun Jiang, Juan Zhao, Yong-An Zhang, Xiao-Qiu Zhou, Lin Feng
The liver and intestine are susceptible to the oxidative damage which could result in several diseases. Choline deficiency induced oxidative damage in rat liver cells. Thus, this study aimed to investigate the potential molecular mechanisms responsible for choline deficiency-induced oxidative damage. Juvenile Jian carp were fed diets differing in choline content [165 (deficient group), 310, 607, 896, 1167 and 1820 mg/kg diet] respectively for 65 days. Oxidative damage, antioxidant enzyme activities and related gene expressions in the hepatopancreas and intestine were measured...
2017: PloS One
https://www.readbyqxmd.com/read/28099498/oral-tolerance-induced-by-ova-intake-ameliorates-tnbs-induced-colitis-in-mice
#12
Lisiery N Paiatto, Fernanda G D Silva, Julia Bier, Márcia R Brochetto-Braga, Áureo T Yamada, Wirla M S C Tamashiro, Patricia U Simioni
INTRODUCTION: Literature data have shown that the consumption of dietary proteins may cause modulatory effects on the host immune system, process denominated oral tolerance by bystander suppression. It has been shown that the bystander suppression induced by dietary proteins can improve inflammatory diseases such as experimental arthritis. Here, we evaluated the effects of oral tolerance induced by ingestion of ovalbumin (OVA) on TNBS-induced colitis in mice, an experimental model for human Crohn's disease...
2017: PloS One
https://www.readbyqxmd.com/read/28099128/bone-health-assessment-of-food-allergic-children-on-restrictive-diets-a-practical-guide
#13
Artemis E Doulgeraki, Emmanouel M Manousakis, Nikolaos G Papadopoulos
BACKGROUND: Food allergy in childhood is on the rise globally and is managed with avoidance diets; recent case reports of food allergic children with nutritional rickets in the literature highlight the importance of close monitoring of bone health in this population. METHODS: There is no consensus as yet with regard to bone health evaluation in food allergic children; therefore, extensive literature search was performed and the existing evidence is presented, along with a relevant algorithm...
January 18, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28098506/capsicum-annuum-var-grossum-bell-pepper-inhibits-%C3%AE-secretase-activity-and-%C3%AE-amyloid1-40-aggregation
#14
Omodesola Oluwafisayo Ogunruku, Ganiyu Oboh, Sabina Passamonti, Federica Trammer, Aline Augusti Boligon
The deposition of amyloid protein as senile plaques is the major signature of Alzheimer's disease (AD). It is produced by the sequential cleavage of the amyloid precursor protein by secretases. Moreover, peppers are noted for their antiaging and cognitive enhancing properties. Thus, in this study, the effects of polyphenol-rich extracts from bell pepper on amyloid production and aggregation in vitro were investigated. Bell pepper (ripe and unripe) was extracted with methanol-1 N HCl (1:1 v/v). Thereafter, the inhibitory potentials of the extracts on β-secretase and β-amyloid1-40 aggregation were determined...
January 18, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28098291/investigation-into-the-bioavailability-of-milk-protein-derived-peptides-with-dipeptidyl-peptidase-iv-inhibitory-activity-using-caco-2-cell-monolayers
#15
Isabelle M E Lacroix, Xiu-Min Chen, David D Kitts, Eunice C Y Li-Chan
In recent years, peptides derived from a variety of dietary proteins have been reported to exhibit inhibitory activity against the dipeptidyl-peptidase IV (DPP-IV) enzyme, a target in the management of type 2 diabetes. While much attention has been given to the production and identification of peptides with DPP-IV inhibitory activity from food proteins, particularly dairy proteins, little is known on the bioavailability of these molecules. In this study, the stability and transport of five previously identified milk-derived peptides (LKPTPEGDL, LPYPY, IPIQY, IPI and WR) and a whey protein isolate (WPI) digest with DPP-IV-inhibitory activity were investigated using Caco-2 cell monolayers as a model system for human intestinal absorption...
January 18, 2017: Food & Function
https://www.readbyqxmd.com/read/28098206/protein-kinase-c-%C3%AE-signaling-is-required-for-dietary-prebiotic-induced-strengthening-of-intestinal-epithelial-barrier-function
#16
Richard Y Wu, Majd Abdullah, Pekka Määttänen, Ana Victoria C Pilar, Erin Scruten, Kathene C Johnson-Henry, Scott Napper, Catherine O'Brien, Nicola L Jones, Philip M Sherman
Prebiotics are non-digestible oligosaccharides that promote the growth of beneficial gut microbes, but it is unclear whether they also have direct effects on the intestinal mucosal barrier. Here we demonstrate two commercial prebiotics, inulin and short-chain fructo-oligosaccharide (scFOS), when applied onto intestinal epithelia in the absence of microbes, directly promote barrier integrity to prevent pathogen-induced barrier disruptions. We further show that these effects involve the induction of select tight junction (TJ) proteins through a protein kinase C (PKC) δ-dependent mechanism...
January 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28098050/dairy-food-supplementation-may-reduce-malnutrition-risk-in-institutionalised-elderly
#17
Sandra Iuliano, Shirley Poon, Xiaofang Wang, Minh Bui, Ego Seeman
Malnutrition in institutionalised elderly increases morbidity and care costs. Meat and dairy foods are high-quality protein sources so adequate intakes may reduce malnutrition risk. We aimed to determine whether inadequate intakes of meat and dairy foods contribute to malnutrition in institutionalised elderly. This cross-sectional study involved 215 elderly residents (70·2 % females, mean age 85·8 years) from twenty-one aged-care facilities in Melbourne, Australia. Dietary intake was assessed using observed plate waste...
January 18, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28098047/vitamin-a-deficiency-suppresses-fish-immune-function-with-differences-in-different-intestinal-segments-the-role-of-transcriptional-factor-nf-%C3%AE%C2%BAb-and-p38-mitogen-activated-protein-kinase-signalling-pathways
#18
Li Zhang, Lin Feng, Wei-Dan Jiang, Yang Liu, Pei Wu, Sheng-Yao Kuang, Ling Tang, Wu-Neng Tang, Yong-An Zhang, Xiao-Qiu Zhou
The present study investigated the effects of dietary vitamin A on immune function in the proximal intestine (PI), mid intestine (MI) and distal intestine (DI) of young grass carp (Ctenopharyngodon idella). Fish were fed graded levels of dietary vitamin A for 10 weeks, and then a challenge test using an injection of Aeromonas hydrophila was conducted for 14 d. The results showed that, compared with the optimum vitamin A level, vitamin A deficiency significantly decreased fish growth performance, increased enteritis morbidity, decreased intestinal innate humoral immune response and aggravated intestinal inflammation...
January 18, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28097602/dietary-supplementation-of-chromium-can-alleviate-negative-impacts-of-heat-stress-on-performance-carcass-yield-and-some-blood-hematology-and-chemistry-indices-of-growing-japanese-quail
#19
Mohamed Soliman El-Kholy, Mohamed Mohamed El-Hindawy, Mahmoud Alagawany, Mohamed Ezzat Abd El-Hack, Sabry Abd El-Gawad Abd El-Halim El-Sayed
The main objective of this work was to investigate the impact of dietary chromium supplementation on growth indices, carcass yield, and some hematological and biochemical blood parameters of growing Japanese quails subjected to heat stress. A total of 360 unsexed 2-week-old Japanese quail chicks were used in a 2 × 3 factorial arrangement that had two ambient temperatures (23 ± 2 and 33 ± 2 °C) and three dietary chromium (0.00, 500, and 1000 μg Cr/kg diet as chromium picolinate). For induction of heat stress, the room temperature was set at 33 ± 2 °C from 2 to 6 weeks of age...
January 17, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28096887/thylakoids-reduce-body-fat-and-fat-cell-size-by-binding-to-dietary-fat-making-it-less-available-for-absorption-in-high-fat-fed-mice
#20
Karin G Stenkula, Eva-Lena Stenblom, Caroline Montelius, Emil Egecioglu, Charlotte Erlanson-Albertsson
BACKGROUND: Dietary thylakoids derived from spinach have beneficial effects on body fat accumulation and blood lipids as demonstrated in humans and rodents. Important mechanisms established include delayed fat digestion in the intestine, without causing steatorrhea, and increased fatty acid oxidation in intestinal cells. The objective of our study was to elucidate if increased fecal fat excretion is an important mechanism to normalize adipose tissue metabolism during high-fat feeding in mice supplemented with thylakoids...
2017: Nutrition & Metabolism
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