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ACL graft maturity

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https://www.readbyqxmd.com/read/29761106/current-strategies-and-future-directions-to-optimize-acl-reconstruction-in-adolescent-patients
#1
Dustin Jon Richter, Roger Lyon, Scott Van Valin, Xue-Cheng Liu
The incidence of anterior cruciate ligament (ACL) injuries in the pediatric population has risen in recent years. These injuries have historically presented a management dilemma in skeletally immature patients with open physes and significant growth remaining at time of injury. While those nearing skeletal maturity may be treated with traditional, transphyseal adult techniques, these same procedures risk iatrogenic damage to the growth plates and resultant growth disturbances in younger patients with open physes...
2018: Frontiers in Surgery
https://www.readbyqxmd.com/read/29727869/a-preclinical-model-to-study-the-influence-of-graft-force-on-the-healing-of-the-anterior-cruciate-ligament-graft
#2
Richard Ma, Mark Stasiak, Xiang-Hua Deng, Scott A Rodeo
The purpose of this study is to establish a small animal anterior cruciate ligament (ACL) reconstruction research model where ACL graft force can be varied to create different graft force patterns with controlled knee motion. Cadaveric ( n  = 10) and in vivo ( n  = 10) rat knees underwent ACL resection followed by reconstruction using a soft tissue autograft. Five cadaveric and five in vivo knees received a nonisometric, high-force femoral graft tunnel position. Five cadaveric and five in vivo knees received a more isometric, low-force graft tunnel position...
May 4, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29574546/graft-bending-angle-affects-allograft-tendon-maturity-early-after-anterior-cruciate-ligament-reconstruction
#3
Linhai Chen, Yibing Wu, Guanghao Lin, Peng Wei, Zaohui Ye, Yangjian Wang, Tiantian Ren
PURPOSE: The aim of this study was to clarify the association of the anterior cruciate ligament (ACL) graft bending angle and graft maturity of autograft and allograft tendons using high-resolution MRI. METHODS: Patients with unilateral ACL reconstruction were invited to participate in this study, and they were examined using a 3.0-T MRI scan at 3, 6 and 12 months after the operation. Anatomic single-bundle ACL reconstruction was performed on 48 patients using the trans-portal technique, including 28 with autograft hamstring tendons and 20 with allograft tendons...
March 24, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29443537/a-randomized-clinical-trial-to-evaluate-attached-hamstring-anterior-cruciate-ligament-graft-maturity-with-magnetic-resonance-imaging
#4
Shaohua Liu, Hong Li, Hongyue Tao, Yaying Sun, Shiyi Chen, Jiwu Chen
BACKGROUND: The hamstring tendons are commonly harvested for anterior cruciate ligament (ACL) reconstruction with detachment of the tibial insertion. Retaining the insertion may help to preserve vascularity and viability of the graft and bypass the stages of avascular necrosis and revascularization, which might be beneficial to graft maturity. PURPOSE: To investigate and compare graft maturity by magnetic resonance imaging (MRI) after ACL reconstruction with preservation or detachment of hamstring tendon tibial insertion at up to 2 years...
April 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29273252/supercritical-carbon-dioxide-sterilized-bone-allograft-in-the-treatment-of-tunnel-defects-in-2-stage-revision-anterior-cruciate-ligament-reconstruction-a-histologic-evaluation
#5
Gerrit J Van de Pol, Fiona Bonar, Lucy J Salmon, Justin P Roe, Leo A Pinczewski
PURPOSE: To examine the histologic properties of supercritical carbon dioxide (sCO2 )-sterilized bone allograft for tunnel grafting and determine in vivo graft quality, as well as graft incorporation and remodeling, in 2-stage revision anterior cruciate ligament (ACL) surgery. METHODS: Histologic evaluation was performed in 12 subjects undergoing 2-stage revision ACL reconstruction. In the first stage, the femoral and tibial tunnels were debrided, tunnel dimensions were measured, and tunnels were grafted with sCO2 -sterilized bone allograft...
March 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29140169/relationship-between-physical-therapy-characteristics-surgical-procedure-and-clinical-outcomes-in-patients-after-acl-reconstruction
#6
Ian J Dempsey, Grant E Norte, Matthew Hall, John Goetschius, Lindsay V Slater, Jourdan M Cancienne, Brian C Werner, David R Diduch, Joseph M Hart
CONTEXT: Post-operative rehabilitation is critical to optimize outcomes after anterior cruciate ligament reconstruction (ACLR). However, the relationship between physical therapy (PT) and clinical outcomes is unclear. OBJECTIVE: To describe PT characteristics following ACLR, and assess the relationships between PT characteristics, surgical procedure, and clinical outcomes. DESIGN: Cross-sectional. SETTING: Laboratory...
November 15, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28840143/allograft-maturation-after-reconstruction-of-the-anterior-cruciate-ligament-is-dependent-on-graft-parameters-in-the-sagittal-plane
#7
Michael Rose, Dennis Crawford
BACKGROUND: Allograft healing (ligamentization) after reconstruction of the anterior cruciate ligament (ACL) is dependent on multiple factors, including tissue processing, host biologic environment, and biomechanical stressors. Magnetic resonance imaging (MRI) can be used to assess graft maturation after ACL reconstruction. HYPOTHESIS: A significant difference will exist in the MRI analysis between 2 distinct allograft constructs. Specifically, the MRI signal-to-noise quotient (SNQ) value will be smaller in quadrupled hamstring tendon (HT) allografts compared with doubled tibialis anterior (TA) allografts due to the difference in graft geometry (surface area-to-volume ratio)...
August 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28756466/anatomic-and-non-anatomic-anterior-cruciate-ligament-posterolateral-bundle-augmentation-affects-graft-function
#8
Can Yapici, Levent Surer, Kenan Keklikci, Dongliang Shi, Soheil Sabzevari, Monica A Linde, Patrick Smolinski, Freddie H Fu
PURPOSE: The purpose of this study is to compare knee laxity and graft function (tissue force) between anatomic and non-anatomic posterolateral (PL) bundle augmentation. METHODS: Twelve (n = 12) fresh-frozen mature, unpaired porcine knees were tested using a robotic testing system. Four knee states were compared: (a) intact anterior cruciate ligament (ACL), (b) deficient PL and intermediate bundles, (c) anatomic PL augmentation, and (d) non-anatomic PL augmentation...
July 29, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28652828/prevention-treatment-and-rehabilitation-of-anterior-cruciate-ligament-injuries-in-children
#9
REVIEW
Pamela J Lang, Dai Sugimoto, Lyle J Micheli
As more children and adolescents participate in competitive organized sports, there has been an increase in the reported incidence of anterior cruciate ligament (ACL) injuries in these age groups. ACL injuries in skeletally immature athletes present a challenge, as reconstruction must preserve the physis of the distal femur and of the proximal tibia to avoid growth disturbances. Historically, a skeletally immature athlete with an ACL injury was treated with a brace and activity modification until skeletal maturity, with ACL reconstruction being performed at that time in the "non-copers" who experienced instability...
2017: Open Access Journal of Sports Medicine
https://www.readbyqxmd.com/read/28324151/higher-hamstring-to-quadriceps-isokinetic-strength-ratio-during-the-first-post-operative-months-in-patients-with-quadriceps-tendon-compared-to-hamstring-tendon-graft-following-acl-reconstruction
#10
Felix Fischer, Christian Fink, Elmar Herbst, Christian Hoser, Caroline Hepperger, Cornelia Blank, Peter Gföller
PURPOSE: The aim of this study was to compare isokinetic quadriceps and hamstring muscle strength in patients following anterior cruciate ligament (ACL) reconstruction who received either hamstring (HT) or quadriceps (QT) tendon autografts at two time intervals within the first year after surgery. METHODS: One hundred twenty-four patients, 81 males (age 22.0 ± 6.2 years) and 43 females (age 20.9 ± 8.7 years), participated in this study. ACL reconstruction was performed with either quadriceps tendon autografts (QT; n = 61) or hamstring tendon autografts (HT; n = 63)...
February 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28135427/is-remnant-preservation-truly-beneficial-to-anterior-cruciate-ligament-reconstruction-healing-clinical-and-magnetic-resonance-imaging-evaluations-of-remnant-preserved-reconstruction
#11
Takuya Naraoka, Yuka Kimura, Eiichi Tsuda, Yuji Yamamoto, Yasuyuki Ishibashi
BACKGROUND: Remnant-preserved anterior cruciate ligament (ACL) reconstruction was introduced to improve clinical outcomes and biological healing. However, the effects of remnant preservation and the influence of the delay from injury until reconstruction on the outcomes of this technique are still uncertain. Purpose/Hypothesis: The purposes of this study were to evaluate whether remnant preservation improved the clinical outcomes and graft incorporation of ACL reconstruction and to examine the influence of the delay between ACL injury and reconstruction on the usefulness of remnant preservation...
April 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28132087/comparison-of-transtibial-and-retrograde-outside-in-techniques-of-anterior-cruciate-ligament-reconstruction-in-terms-of-graft-nature-and-clinical-outcomes-a-case-control-study-using-3t-mri
#12
COMPARATIVE STUDY
Jin Hwan Ahn, Yong Seuk Lee, Hwa Jae Jeong, Jai Hyung Park, Yohan Cho, Kwang-Jeong Kim, Taeg Su Ko
INTRODUCTION: This study was performed to compare ACL graft maturation and morphologies using MRI between trans-tibial (TT) and retrograde outside-in (OI) techniques, and to compare clinical outcomes between the two groups. MATERIALS AND METHODS: Patients underwent single-tunnel ACL reconstruction using quadrupled hamstring autografts, with the TT technique used on 42 patients (TT group) and the retrograde OI technique used on 39 patients (OI group). All patients were examined with 3 T MRI at 6 months (between 5 and 7 months) after surgery...
March 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/27766344/anterior-laxity-and-patient-reported-outcomes-7%C3%A2-years-after-acl-reconstruction-with-a-fresh-frozen-tibialis-allograft
#13
Emily Meike, S M Howell, M L Hull
PURPOSE: After reconstructing a torn ACL with a soft tissue allograft, the long-term healing process of graft maturation following the short-term healing process of graft incorporation into the bone tunnels might lead to recurring instability and concomitant decreases in the activity level, function, and patient satisfaction. Relying on roentgen stereophotogrammetric analysis (RSA), the primary purpose was to determine whether anterior laxity increased and whether patient-reported outcomes declined between 1 and 7 years for a particular graft construct, surgical technique, and rehabilitation programme...
May 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27672573/biologic-agents-for-anterior-cruciate-ligament-healing-a-systematic-review
#14
Berardo Di Matteo, Markus Loibl, Luca Andriolo, Giuseppe Filardo, Johannes Zellner, Matthias Koch, Peter Angele
AIM: To systematically review the currently available literature concerning the application of biologic agents such as platelet-rich plasma (PRP) and stem cells to promote anterior cruciate ligament (ACL) healing. METHODS: A systematic review of the literature was performed on the use of biologic agents (i.e., PRP or stem cells) to favor ACL healing during reconstruction or repair. The following inclusion criteria for relevant articles were used: Clinical reports of any level of evidence, written in English language, on the use of PRP or stem cells during ACL reconstruction/repair...
September 18, 2016: World Journal of Orthopedics
https://www.readbyqxmd.com/read/27634652/revascularisation-pattern-of-ruptured-flexor-tendon-grafts-in-anterior-cruciate-ligament-reconstruction-a-histological-study
#15
COMPARATIVE STUDY
D Figueroa, R Martínez, R Calvo, M Scheu, M Gallegos, A Vaisman, C Martínez, A González
INTRODUCTION: For successful anterior cruciate ligament (ACL) reconstruction, revascularisation and histological maturation are necessary, as their failure can cause graft rupture. PURPOSE: The purpose of this study was to describe differences in the histological maturation of early failed plasty (less than 12 months after surgery) and late failed plasty (more than 12 months after surgery) in patients with re-rupture after ACL reconstruction with hamstring tendons...
November 2016: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/27511027/mri-signal-intensity-of-anterior-cruciate-ligament-graft-after-transtibial-versus-anteromedial-portal-technique-transig-design-of-a-randomized-controlled-clinical-trial
#16
RANDOMIZED CONTROLLED TRIAL
Simeon J S Ruiter, Reinoud W Brouwer, Tim W G M Meys, Cornelis H Slump, Jos J A M van Raay
BACKGROUND: There are two primary surgical techniques to reconstruct the anterior cruciate ligament (ACL), transtibial (TT) technique and anteromedial portal (AMP) technique. Currently, there is no consensus which surgical technique elicits the best clinical and functional outcomes. MRI-derived measures of the signal intensity (SI) of the ACL graft have been described as an independent predictor of graft properties. The purpose of this study is to compare the MRI derived SI measurements of the ACL graft one year after ACL reconstruction, in order to compare the outcomes of both the AMP and TT ACL reconstruction technique...
August 10, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27485123/mri-based-acl-graft-maturity-does-not-predict-clinical-and-functional-outcomes-during-the-first-year-after-acl-reconstruction
#17
Hong Li, Jiwu Chen, Hongyun Li, Ziying Wu, Shiyi Chen
PURPOSE: To determine whether magnetic resonance image (MRI)-based graft maturity predicts clinical and functional scores during the first year after ACL reconstruction. METHODS: Patients with unilateral ACL reconstruction were prospectively invited to participate in this study, and they were examined using a 3.0-T MRI scan at 3, 6, and 12 months after the operation. Clinical examinations were performed on the same day, including subjective functional examinations, physical examinations and the KT-1000 test...
October 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27438006/does-sterilization-with-fractionated-electron-beam-irradiation-prevent-acl-tendon-allograft-from-tissue-damage
#18
T Schmidt, D Grabau, J H Grotewohl, U Gohs, A Pruß, M Smith, S Scheffler, A Hoburg
PURPOSE: Allografts are frequently used for anterior cruciate ligament (ACL) reconstruction. However, due to the inherent risk of infection, a method that achieves complete sterilization of grafts is warranted without impairing their biomechanical properties. Fractionation of electron beam (FEbeam) irradiation has been shown to maintain similar biomechanical properties compared to fresh-frozen allografts (FFA) in vitro. Therefore, aim of this study was to evaluate the biomechanical properties and early remodelling of grafts that were sterilized with fractionated high-dose electron beam irradiation in an in vivo sheep model...
February 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27379789/risk-factors-for-early-acl-reconstruction-failure-in-pediatric-and-adolescent-patients-a-review-of-561-cases
#19
Brian Ho, Eric W Edmonds, Henry G Chambers, Tracey P Bastrom, Andrew T Pennock
BACKGROUND: Anterior cruciate ligament (ACL) reconstruction failure is relatively common in young high-risk athletes. The purpose of this study was to examine a single center's 10-year experience with ACL reconstructions in pediatric and adolescent patients to better define short-term failure rates and risk factors for revision ACL surgery. METHODS: This institutional review board-approved retrospective study included all patients who underwent a primary ACL reconstruction between 2002 and 2013...
July 2, 2016: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/27349433/anterior-cruciate-ligament-reconstruction-with-bone-patellar-tendon-bone-autograft-versus-allograft-in-skeletally-mature-patients-aged-25%C3%A2-years-or-younger
#20
COMPARATIVE STUDY
Patrick W Kane, Jocelyn Wascher, Christopher C Dodson, Sommer Hammoud, Steven B Cohen, Michael G Ciccotti
PURPOSE: The purpose of this study is to evaluate the clinical outcomes and revision rates of skeletally mature patients aged 25 years or younger who have undergone either BPTB autograft or deep-frozen, non-irradiated BPTB allograft ACL reconstruction by a single surgeon. METHODS: Two hundred and twenty-four patients aged 25 or younger at the time of surgery were identified as having a transtibial ACL reconstruction with either a BPTB autograft or deep-frozen, non-irradiated BPTB allograft by one senior surgeon (101 autografts vs...
November 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
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