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https://www.readbyqxmd.com/read/27914036/prolactin-regulatory-element-binding-protein-is-involved-in-suppression-of-the-adiponectin-gene-in-vivo
#1
X Z Zhang, H Imachi, J Y Lyu, K Fukunaga, S Sato, T Ibata, T Kobayashi, T Yoshimoto, F Kikuchi, T Dong, K Murao
PURPOSE: Prolactin regulatory element-binding protein (PREB), a member of the WD-repeat protein family, has been recognized as a transcriptional factor that regulates prolactin promoter activity in the anterior pituitary of rats. PREB is expressed not only in the pituitary but also in various other tissues, including the adipose tissue. Previous studies have shown that PREB acts as a transcriptional regulator and suppresses the expression of the adiponectin gene in cultured 3T3L1 preadipocytes...
December 2, 2016: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/27913983/mobile-health-technology-can-objectively-capture-physical-activity-pa-targets-among-african-american-women-within-resource-limited-communities-the-washington-d-c-cardiovascular-health-and-needs-assessment
#2
S Thomas, L Yingling, J Adu-Brimpong, V Mitchell, C R Ayers, G R Wallen, M Peters-Lawrence, A T Brooks, D M Sampson, K L Wiley, J Saygbe, J Henry, A Johnson, A Graham, L Graham, T M Powell-Wiley
BACKGROUND: Little is understood about using mobile health (mHealth) technology to improve cardiovascular (CV) health among African-American women in resource-limited communities. METHODS: We conducted the Washington, D.C. CV Health and Needs Assessment in predominantly African-American churches in city wards 5, 7, and 8 with the lowest socioeconomic status based on community-based participatory research (CBPR) principles. The assessment measured CV health factors: body mass index (BMI), fasting blood glucose and cholesterol, blood pressure, fruit/vegetable (F/V) intake, physical activity (PA), and smoking...
December 2, 2016: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/27913851/impact-of-oxygenation-on-the-performance-of-three-non-saccharomyces-yeasts-in-co-fermentation-with-saccharomyces-cerevisiae
#3
Kirti Shekhawat, Florian F Bauer, Mathabatha E Setati
The sequential or co-inoculation of grape must with non-Saccharomyces yeast species and Saccharomyces cerevisiae wine yeast strains has recently become a common practice in winemaking. The procedure intends to enhance unique aroma and flavor profiles of wine. The extent of the impact of non-Saccharomyces strains depends on their ability to produce biomass and to remain metabolically active for a sufficiently long period. However, mixed-culture wine fermentations tend to become rapidly dominated by S. cerevisiae, reducing or eliminating the non-Saccharomyces yeast contribution...
December 2, 2016: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/27913818/-amyloid-positron-emission-tomography-with-18-%C3%A2-f-florbetaben-in-the-diagnostic-workup-of-dementia-patients
#4
S Schönecker, C Prix, T Raiser, N Ackl, E Wlasich, G Stenglein-Krapf, E Mille, M Brendel, O Sabri, M Patt, H Barthel, P Bartenstein, J Levin, A Rominger, A Danek
BACKGROUND: To this day the definite diagnosis of Alzheimer's disease still relies on post-mortem histopathological detection of neurofibrillary tangles and beta-amyloid deposits. Amyloid positron emission tomography (PET) is a new diagnostic tool that enables the in vivo quantification of pathological beta-amyloid deposits. The aim of the current study was to evaluate to what extent (18)F-florbetaben-PET (FBB-PET) influences the diagnosis of patients with dementia. MATERIAL AND METHODS: Imaging with FBB-PET was performed on 33 patients from our outpatient department for cognitive neurology...
December 2, 2016: Der Nervenarzt
https://www.readbyqxmd.com/read/27913160/psychological-well-being-and-mental-health-recovery-in-the-nimh-raise-early-treatment-program
#5
Julia Browne, David L Penn, Piper S Meyer-Kalos, Kim T Mueser, Sue E Estroff, Mary F Brunette, Christoph U Correll, James Robinson, Robert A Rosenheck, Nina Schooler, Delbert G Robinson, Jean Addington, Patricia Marcy, John M Kane
Recovery-oriented practices that promote client-centered care, collaboration, and functional outcome have been recommended to improve treatment engagement, especially for individuals with serious mental illness (SMI). Psychological well-being (PWB) is related to recovery and refers to experiencing purpose and meaning in life through realizing one's potential. The recently completed Recovery After an Initial Schizophrenia Episode Early Treatment Program (RAISE ETP) study sought to improve quality of life, functional outcome, and well-being in individuals with first episode psychosis (FEP)...
November 29, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27913108/chicken-line-dependent-mortality-after-experimental-infection-with-three-type-iixiii-recombinant-toxoplasma-gondii-clones
#6
G Schares, D C Herrmann, P Maksimov, B Matzkeit, F J Conraths, G Moré, R Preisinger, S Weigend
Three genetically different clones of Toxoplasma gondii, also different in mouse virulence, were studied by experimental infection in chickens. For the experiments, four chicken lines were used, which differed in phylogenetic origin and performance level: two white egg layer lines, one with high laying performance (WLA), one with low (R11) and two brown layer lines, also displaying high (BLA) and low (L68) egg number. Chickens were intraperitoneally infected with three different T. gondii isolates representing type IIxIII recombinant clones, i...
November 29, 2016: Experimental Parasitology
https://www.readbyqxmd.com/read/27912930/prognostic-significance-of-venous-invasion-and-maximum-standardized-uptake-value-of-18-f-fdg-pet-ct-in-surgically-resected-t1n0-esophageal-squamous-cell-carcinoma
#7
J H Jeon, J M Lee, D H Moon, H C Yang, M S Kim, G-K Lee, J I Zo
BACKGROUND: The purpose of this study was to analyze the risk factors of recurrence in patients with early stage esophageal squamous cell carcinoma (ESCC). METHODS: We retrospectively analyzed the medical records of 190 patients with confirmed T1N0M0 ESCC after curative esophagectomy. The following potential prognostic factors for recurrence were investigated: age, sex, pathologic T category, tumor location, differentiation grade, tumor size, venous invasion, angiolymphatic invasion, perineural invasion and the maximum standardized uptake value (SUVmax) of the primary tumor...
November 22, 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27912789/dynamics-of-antigenemia-and-transmission-intensity-of-wuchereria-bancrofti-following-cessation-of-mass-drug-administration-in-a-formerly-highly-endemic-region-of-mali
#8
Yaya I Coulibaly, Siaka Y Coulibaly, Housseini Dolo, Siaka Konate, Abdallah A Diallo, Salif S Doumbia, Lamine Soumaoro, Michel E Coulibaly, Ilo Dicko, Moussa B Sangare, Benoit Dembele, Modibo Sangare, Massitan Dembele, Yeya T Touré, Louise Kelly-Hope, Katja Polman, Dominique Kyelem, Sekou F Traore, Moses Bockarie, Amy D Klion, Thomas B Nutman
BACKGROUND: After seven annual rounds of mass drug administration (MDA) in six Malian villages highly endemic for Wuchereria bancrofti (overall prevalence rate of 42.7%), treatment was discontinued in 2008. Surveillance was performed over the ensuing 5 years to detect recrudescence. METHODS: Circulating filarial antigen (CFA) was measured using immunochromatographic card tests (ICT) and Og4C3 ELISA in 6-7 year-olds. Antibody to the W. bancrofti infective larval stage (L3) antigen, Wb123, was tested in the same population in 2012...
December 3, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27911887/probing-the-spiral-magnetic-phase-in-6%C3%A2-nm-textured-erbium-using-polarised-neutron-reflectometry
#9
N Satchell, J D S Witt, G Burnell, P J Curran, C J Kinane, T R Charlton, S Langridge, J F K Cooper
We characterise the magnetic state of highly-textured, sputter deposited erbium for a film of thickness 6 nm. Using polarised neutron reflectometry it is found that the film has a high degree of magnetic disorder, and we present some evidence that the film's local magnetic state is consistent with bulk-like spiral magnetism. This, combined with complementary characterisation techniques, show that thin film erbium is a strong candidate material for incorporation into device structures.
December 2, 2016: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/27910679/neutron-emission-spectroscopy-of-dt-plasmas-at-enhanced-energy-resolution-with-diamond-detectors
#10
L Giacomelli, M Nocente, M Rebai, D Rigamonti, A Milocco, M Tardocchi, Z J Chen, T F Du, T S Fan, Z M Hu, X Y Peng, A Hjalmarsson, G Gorini
This work presents measurements done at the Peking University Van de Graaff neutron source of the response of single crystal synthetic diamond (SD) detectors to quasi-monoenergetic neutrons of 14-20 MeV. The results show an energy resolution of 1% for incoming 20 MeV neutrons, which, together with 1% detection efficiency, opens up to new prospects for fast ion physics studies in high performance nuclear fusion devices such as SD neutron spectrometry of deuterium-tritium plasmas heated by neutral beam injection...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910640/calibration-of-the-microcalorimeter-spectrometer-on-board-the-hitomi-astro-h-observatory-invited
#11
M E Eckart, K R Boyce, G V Brown, M P Chiao, R Fujimoto, D Haas, J-W den Herder, Y Ishisaki, R L Kelley, C A Kilbourne, M A Leutenegger, D McCammon, K Mitsuda, F S Porter, M Sawada, G A Sneiderman, A E Szymkowiak, Y Takei, M Tashiro, M Tsujimoto, C P de Vries, T Watanabe, S Yamada, N Y Yamasaki
The Hitomi Soft X-ray Spectrometer (SXS) was a pioneering non-dispersive imaging x-ray spectrometer with 5 eV FWHM energy resolution, consisting of an array of 36 silicon-thermistor microcalorimeters at the focus of a high-throughput soft x-ray telescope. The instrument enabled astrophysical plasma diagnostics in the 0.3-12 keV band. We introduce the SXS calibration strategy and corresponding ground calibration measurements that took place from 2012-2015, including both the characterization of the microcalorimeter array and measurements of the x-ray transmission of optical blocking filters...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910630/sensitivity-of-mse-measurements-on-the-beam-atomic-level-population
#12
C Ruiz, S T A Kumar, F S B Anderson, D T Anderson
The effect of variation in atomic level population of a neutral beam on the Motional Stark Effect (MSE) measurements is investigated in the low density plasmas of HSX stellarator. A 30 KeV, 4 A, 3 ms hydrogen diagnostic neutral beam is injected into HSX plasmas of line averaged electron density ranging from 2 to 4 ⋅ 10(18) m(-3) at a magnetic field of 1 T. For this density range, the excited level population of the hydrogen neutral beam is expected to undergo variations. Doppler shifted and Stark split Hα and Hβ emissions from the beam are simultaneously measured using two cross-calibrated spectrometers...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910626/a-high-resolving-power-x-ray-spectrometer-for-the-omega-ep-laser-invited
#13
P M Nilson, F Ehrne, C Mileham, D Mastrosimone, R K Jungquist, C Taylor, C R Stillman, S T Ivancic, R Boni, J Hassett, D J Lonobile, R W Kidder, M J Shoup, A A Solodov, C Stoeckl, W Theobald, D H Froula, K W Hill, L Gao, M Bitter, P Efthimion, D D Meyerhofer
A high-resolving-power x-ray spectrometer has been developed for the OMEGA EP Laser System based on a spherically bent Si [220] crystal with a radius of curvature of 330 mm and a Spectral Instruments (SI) 800 Series charge-coupled device. The instrument measures time-integrated x-ray emission spectra in the 7.97- to 8.11-keV range, centered on the Cu Kα1 line. To demonstrate the performance of the spectrometer under high-power conditions, Kα1,2 emission spectra were measured from Cu foils irradiated by the OMEGA EP laser with 100-J, 1-ps pulses at focused intensities above 10(18) W/cm(2)...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910612/jet-diagnostic-enhancements-in-preparation-for-dt-operations
#14
J Figueiredo, A Murari, C Perez Von Thun, D Marocco, M Tardocchi, F Belli, M García Muñoz, A Silva, S Soare, T Craciunescu, M Santala, P Blanchard, I Balboa, N Hawkes
In order to complete the exploitation of the JET ITER-like Wall and to take full benefit from deuterium-tritium experiments on JET, a set of diagnostic system refurbishments or upgrades is in progress. These diagnostic enhancements focus mainly on neutron, gamma, fast ions, instabilities, and operations support. These efforts intend to provide better spatial, temporal, and energy resolution while increasing measurement coverage. Also previously non-existing capabilities, such as Doppler reflectometry is now available for scientific exploitation...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910604/response-function-of-single-crystal-synthetic-diamond-detectors-to-1-4-mev-neutrons-for-spectroscopy-of-d-plasmas
#15
M Rebai, L Giacomelli, A Milocco, M Nocente, D Rigamonti, M Tardocchi, F Camera, C Cazzaniga, Z J Chen, T F Du, T S Fan, A Giaz, Z M Hu, T Marchi, X Y Peng, G Gorini
A Single-crystal Diamond (SD) detector prototype was installed at Joint European Torus (JET) in 2013 and the achieved results have shown its spectroscopic capability of measuring 2.5 MeV neutrons from deuterium plasmas. This paper presents measurements of the SD response function to monoenergetic neutrons, which is a key point for the development of a neutron spectrometer based on SDs and compares them with Monte Carlo simulations. The analysis procedure allows for a good reconstruction of the experimental results...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910599/synthetic-plasma-edge-diagnostics-for-emc3-eirene-highlighted-for-wendelstein-7-x
#16
H Frerichs, F Effenberg, O Schmitz, C Biedermann, Y Feng, M Jakubowski, R König, M Krychowiak, J Lore, H Niemann, T S Pedersen, L Stephey, G A Wurden
Interpretation of spectroscopic measurements in the edge region of high-temperature plasmas can be a challenge since line of sight integration effects make direct interpretation in terms of quantitative, local emission strengths often impossible. The EMC3-EIRENE code-a 3D fluid edge plasma and kinetic neutral gas transport code-is a suitable tool for full 3D reconstruction of such signals. A versatile synthetic diagnostic module has been developed recently which allows the realistic 3D setup of various plasma edge diagnostics to be captured...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910594/quantitative-low-energy-ion-beam-characterization-by-beam-profiling-and-imaging-via-scintillation-screens
#17
S Germer, F Pietag, J Polak, T Arnold
This study presents the imaging and characterization of low-current ion beams in the neutralized state monitored via single crystal YAG:Ce (Y3Al5O12) scintillators. To validate the presented beam diagnostic tool, Faraday cup measurements and test etchings were performed. Argon ions with a typical energy of 1.0 keV were emitted from an inductively coupled radio-frequency (13.56 MHz) ion beam source with total currents of some mA. Different beam properties, such as, lateral ion current density, beam divergence angle, and current density in pulsed ion beams have been studied to obtain information about the spatial beam profile and the material removal rate distribution...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910586/a-novel-method-to-recover-dd-fusion-proton-cr-39-data-corrupted-by-fast-ablator-ions-at-omega-and-the-national-ignition-facility
#18
G D Sutcliffe, L M Milanese, D Orozco, B Lahmann, M Gatu Johnson, F H Séguin, H Sio, J A Frenje, C K Li, R D Petrasso, H-S Park, J R Rygg, D T Casey, R Bionta, D P Turnbull, C M Huntington, J S Ross, A B Zylstra, M J Rosenberg, V Yu Glebov
CR-39 detectors are used routinely in inertial confinement fusion (ICF) experiments as a part of nuclear diagnostics. CR-39 is filtered to stop fast ablator ions which have been accelerated from an ICF implosion due to electric fields caused by laser-plasma interactions. In some experiments, the filtering is insufficient to block these ions and the fusion-product signal tracks are lost in the large background of accelerated ion tracks. A technique for recovering signal in these scenarios has been developed, tested, and implemented successfully...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910566/hotspot-electron-temperature-from-x-ray-continuum-measurements-on-the-nif
#19
L C Jarrott, L R Benedetti, H Chen, N Izumi, S F Khan, T Ma, S R Nagel, O L Landen, A Pak, P K Patel, M Schneider, H A Scott
We report on measurements of the electron temperature in the hotspot of inertially confined, layered, spherical implosions on the National Ignition Facility using a differential filtering diagnostic. Measurements of the DT and DD ion temperatures using neutron time-of-flight detectors are complicated by the contribution of hot spot motion to the peak width, which produce an apparent temperature higher than the thermal temperature. The electron temperature is not sensitive to this non-thermal velocity and is thus a valuable input to interpreting the stagnated hot spot conditions...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910557/a-storage-ring-experiment-to-detect-a-proton-electric-dipole-moment
#20
V Anastassopoulos, S Andrianov, R Baartman, S Baessler, M Bai, J Benante, M Berz, M Blaskiewicz, T Bowcock, K Brown, B Casey, M Conte, J D Crnkovic, N D'Imperio, G Fanourakis, A Fedotov, P Fierlinger, W Fischer, M O Gaisser, Y Giomataris, M Grosse-Perdekamp, G Guidoboni, S Hacıömeroğlu, G Hoffstaetter, H Huang, M Incagli, A Ivanov, D Kawall, Y I Kim, B King, I A Koop, D M Lazarus, V Lebedev, M J Lee, S Lee, Y H Lee, A Lehrach, P Lenisa, P Levi Sandri, A U Luccio, A Lyapin, W MacKay, R Maier, K Makino, N Malitsky, W J Marciano, W Meng, F Meot, E M Metodiev, L Miceli, D Moricciani, W M Morse, S Nagaitsev, S K Nayak, Y F Orlov, C S Ozben, S T Park, A Pesce, E Petrakou, P Pile, B Podobedov, V Polychronakos, J Pretz, V Ptitsyn, E Ramberg, D Raparia, F Rathmann, S Rescia, T Roser, H Kamal Sayed, Y K Semertzidis, Y Senichev, A Sidorin, A Silenko, N Simos, A Stahl, E J Stephenson, H Ströher, M J Syphers, J Talman, R M Talman, V Tishchenko, C Touramanis, N Tsoupas, G Venanzoni, K Vetter, S Vlassis, E Won, G Zavattini, A Zelenski, K Zioutas
A new experiment is described to detect a permanent electric dipole moment of the proton with a sensitivity of 10(-29) e ⋅ cm by using polarized "magic" momentum 0.7 GeV/c protons in an all-electric storage ring. Systematic errors relevant to the experiment are discussed and techniques to address them are presented. The measurement is sensitive to new physics beyond the standard model at the scale of 3000 TeV.
November 2016: Review of Scientific Instruments
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