S A Riesle-Sbarbaro, G Wibbelt, A Düx, V Kouakou, M Bokelmann, K Hansen-Kant, N Kirchoff, M Laue, N Kromarek, A Lander, U Vogel, A Wahlbrink, D M Wozniak, D P Scott, J B Prescott, L Schaade, E Couacy-Hymann, A Kurth
The natural reservoir of Ebola virus (EBOV), agent of a zoonosis burdening several African countries, remains unidentified, albeit evidence points towards bats. In contrast, the ecology of the related Marburg virus is much better understood; with experimental infections of bats being instrumental for understanding reservoir-pathogen interactions. Experiments have focused on elucidating reservoir competence, infection kinetics and specifically horizontal transmission, although, vertical transmission plays a key role in many viral enzootic cycles...
January 31, 2024: Nature Communications