keyword
MENU ▼
Read by QxMD icon Read
search

High responder

keyword
https://www.readbyqxmd.com/read/28821672/audio-visual-modulation-in-mouse-v1-depends-on-cross-modal-stimulus-configuration-and-congruency
#1
Guido T Meijer, Jorrit S Montijn, Cyriel M A Pennartz, Carien S Lansink
The sensory neocortex is a highly connected associative network, in which information from multiple senses is integrated, even at the level of the primary sensory areas. Although this view is supported by a growing body of empirical evidence, the neural mechanisms of cross-modal integration in primary sensory areas, such as the primary visual cortex (V1), are still largely unknown. Using two-photon calcium imaging in awake mice, we show that the encoding of audio-visual stimuli in V1 neuronal populations is highly dependent on the features of the stimulus constituents...
August 8, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28821528/post-traumatic-stress-disorder-in-adult-victims-of-cluster-munitions-in-lebanon-a-10-year-longitudinal-study
#2
Jawad Fares, Souheil Gebeily, Mohamad Saad, Hayat Harati, Sanaa Nabha, Najwane Said, Mohamad Kanso, Ronza Abdel Rassoul, Youssef Fares
OBJECTIVE: This study aims to explore the short-term and long-term prevalence and effects of post-traumatic stress disorder (PTSD) among victims of cluster munitions. DESIGN AND SETTING: A prospective 10-year longitudinal study that took place in Lebanon. PARTICIPANTS: Two-hundred-and-forty-four Lebanese civilian victims of submunition blasts, who were injured in 2006 and were over 18 years old, were interviewed. Included were participants who had been diagnosed with PTSD according to the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) and the PTSD Checklist - Civilian Version in 2006...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28821422/adhesion-molecules-chemokines-and-matrix-metallo-proteinases-response-after-albendazole-and-albendazole-plus-steroid-therapy-in-swine-neurocysticercosis
#3
Satyendra K Singh, Kashi N Prasad, Aloukick K Singh, Kamlesh K Gupta, Amrita Singh, Mukesh Tripathi, Rakesh K Gupta
The treatment of neurocysticercosis (NCC) varies with location, number and stage of the Taenia solium cysticerci (cysts). Albendazole (ABZ) effectively kills cysticerci, and subsequently induces neuro-inflammation facilitated by leukocyte infiltration. We hypothesize that immune response varies around drug responder (degenerating/dying) and non-responder (viable) cysts after ABZ and ABZ plus steroid (ABZS) therapy, which may determine the disease pathogenesis. Twenty cysticercotic swine were treated with ABZ (n = 10; group1) and ABZS (n = 10; group2)...
August 15, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28821075/rapid-fabrication-of-transparent-film-directly-from-wood-fibers-with-microwave-assisted-ionic-liquids-technology
#4
Pengbo Lu, Fan Cheng, Yanghao Ou, Meiyan Lin, Lingfeng Su, Size Chen, Xilang Yao, Detao Liu
Presently flexibly transparent film or nanopaper from all cellulose was mostly fabricated by assembling cellulose nanofibers disintegrated from macroscopic wood fibers which mostly suffers from potential environmental toxicity or high cost. In this work, we firstly reported an all-cellulose transparent film fabricated by a novel microwave-assisted ionic liquids technology (MILT). The use of MILT for treating the original all-cellulose paper brings nearly 2.6 fold-increases in optical transmission, and 2.0 fold-increases in tensile property compared to those without microwave assistance...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28820672/association-of-religion-and-cultural-tradition-with-alcohol-use-among-some-tribal-communities-of-arunachal-pradesh-india
#5
Himanshu K Chaturvedi, Ram C Bajpai, Preeti Tiwari
Arunachal Pradesh, a land of high mountains and dense forest, is home to many tribal communities, which comprise two thirds of the state's population. Alcohol is one of the common addictive substances used traditionally among them despite much awareness about its harmful effect on health. The present study is focused on finding the association of religion, ethnicity, and demographic characteristics with alcohol use among some tribal communities in Changlang district of Arunachal Pradesh. A cross-sectional household survey was conducted on substance use in Changlang district of Arunachal Pradesh, India...
August 18, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/28820314/flow-pattern-dependent-endothelial-cell-responses-through-transcriptional-regulation
#6
Hiroyuki Nakajima, Naoki Mochizuki
Blood flow provides endothelial cells (ECs) lining the inside of blood vessels with mechanical stimuli as well as humoral stimuli. Fluid shear stress, the frictional force between flowing blood and ECs, is recognized as an essential mechanical cue for vascular growth, remodeling, and homeostasis. ECs differentially respond to distinct flow patterns. High laminar shear flow leads to inhibition of cell cycle progression and stabilizes vessels, whereas low shear flow or disturbed flow leads to increased turnover of ECs and inflammatory responses of ECs prone to atherogenic...
August 18, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28820273/psychological-distress-health-and-treatment-related-factors-among-individuals-initiating-art-in-oromia-ethiopia
#7
Angela M Parcesepe, Olga Tymejczyk, Robert Remien, Tsigereda Gadisa, Sarah Gorrell Kulkarni, Susie Hoffman, Zenebe Melaku, Batya Elul, Denis Nash
HIV diagnosis may be a source of psychological distress. Late initiation of antiretroviral therapy (ART) and treatment-related beliefs may intensify psychological distress among those recently diagnosed. This analysis describes the prevalence of psychological distress among people living with HIV (PLWH) and examines the association of recent HIV diagnosis, late ART initiation and treatment-related beliefs with psychological distress. The sample includes 1175 PLWH aged 18 or older initiating ART at six HIV clinics in Ethiopia...
August 18, 2017: AIDS Care
https://www.readbyqxmd.com/read/28820170/paradoxical-worsening-of-a-case-of-tb-subretinal-abscess-with-serpiginous-like-choroiditis-following-the-initiation-of-antitubercular-therapy
#8
Sudha K Ganesh, B Sowkath Ali
A 37-year-old immunocompetent male patient presented with the blurring of vision, both eyes for the past1 year. Fundus examination revealed bilateral multiple subretinal abscesses with areas of healed serpiginous-like choroiditis. Laboratory investigations showed positive tuberculin skin test, positive QuantiFERON TB-Gold Test, and high resolution computed tomography chest showed enlarged mediastinal lymph nodes. The aqueous sample revealed polymerase chain reaction (PCR) positive for Mycobacterium tuberculosis (MTB) (MPB64 genome)...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28820072/structural-design-and-physicochemical-foundations-of-hydrogels-for-biomedical-and-pharmaceutical-applications
#9
Qingyong Li, Wen Li, Jie Xu, Zhengxiang Ning, Jiaoyan Ren, Wenzhen Liao
Biomedical research, known as medical research, is conducive to support and promote the development of knowledge in the field of medicine. Hydrogels have been extensively used in many biomedical fields due to theirs highly absorbent and flexible properties. The smart hydrogels, especially, can respond to a broad range of external stimuli such as temperature, pH value, light, electric and magnetic fields. With excellent biocompatibility, tunable rheology, mechanical properties, porosity, and hydrated molecular structure, hydrogels are considered as promising candidate for simulating local tissue microenvironment...
August 17, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28819571/incidental-finding-of-an-undiagnosed-coarctation-of-the-aorta-causing-dilated-cardiomyopathy-in-an-adult
#10
Abdalla Ibrahim, Zahir Satti, Ronan Curtin
31-year-old male with no past medical history apart from high blood pressure noted by GP one week prior to admission presented with a three-week history of a flu-like illness and symptoms of heart failure with severe global left ventricular dilation and dysfunction on Transthoracic Echocardiography (TTE). Two weeks following admission he complained of left arm pain and CT upper limb confirmed embolic occlusion of the left brachial artery and incidental severe coarctation of the proximal descending aorta after the origin of the left subclavian artery...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28819511/male-partner-involvement-in-the-prevention-of-mother-to-child-transmission-of-hiv-infection-in-mwanza-region-tanzania
#11
Munda Elias, Elia John Mmbaga, Ahmed Abade Mohamed, Rogath Saika Kishimba
INTRODUCTION: Globally, there are 3.3 million children < 15 years of age living with HIV infection. About 95% of HIV infected children have acquired infection from their mothers. Although new pediatric HIV infection in Tanzania has declined by 48% and Prevention of Mother to Child Transmission (PMTCT) coverage of highly active anti-retroviral therapy (HAART) has increased to 77%, the MTCT rate remains high (15%). Poor male partner involvement in PMTCT services is one of the factors contributing to reduced effectiveness of the PMTCT and hence failure to achieve the elimination of maternal to child transmission of HIV...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28819508/perceived-risk-of-reinfection-among-individuals-treated-for-sexually-transmitted-infections-in-northern-ethiopia-implication-for-use-in-clinical-practice
#12
Mache Tsadik, Yemane Berhane, Alemayehu Worku, Wondwossen Terefe
INTRODUCTION: The prevention of reinfection of sexually transmitted infections (STIs) is highly dependent on the level of risk perception and the subsequent adoption of preventive behaviors. While perceived risk is assumed to be key to adoption of preventive measures, the evidence regarding the predictors of perceived risk to STI reinfection are limited. METHODS: This paper is based on a cross sectional facility based survey conducted in North Ethiopia from January to June; 2015...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28819495/birth-preparedness-and-complication-readiness-among-pregnant-women-in-osogbo-metropolis-southwest-nigeria
#13
Adedayo Olukemi Sabageh, Oluwatosin Adediran Adeoye, Adeleye Abiodun Adeomi, Donatus Sabageh, Adebola Afolake Adejimi
INTRODUCTION: High maternal mortality is a major problem in Nigeria. Birth Preparedness and Complication Readiness will ensure that women can have professional delivery thus reducing obstetric complications. This study assessed the birth preparedness and complication readiness among pregnant women in Osogbo metropolis, a south western community in Nigeria. METHODS: A community based descriptive cross sectional survey was used. A total of 180 women were selected using multistage sampling technique...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28818587/phenanthrene-responsive-micrornas-and-their-targets-in-wheat-roots
#14
Jinfeng Li, Le Yue, Yu Shen, Yu Sheng, Xinhua Zhan, Guohua Xu, Baoshan Xing
MicroRNAs (miRNAs) play key roles in plant growth, development and responses to abiotic stress. Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants. However, it is yet unknown how miRNAs work during PAH uptake by plant roots. Thus, in this study we ascertain phenanthrene (a model PAH)-responsive miRNAs using small RNA high-throughput deep sequencing and their target genes in wheat roots. We identified 108 conserved and non-conserved miRNA members belonging to 82 miRNA families and found 11 differentially expressed miRNAs, among which four miRNAs (miR156, miR164, miR171a and miR9678-3p) were up-regulated and the other seven miRNAs (miR398, miR531, miR1121, miR5048-5p, miR9653b, miR9773 and miR9778) were down-regulated...
August 8, 2017: Chemosphere
https://www.readbyqxmd.com/read/28818546/glecaprevir-plus-pibrentasvir-for-chronic-hepatitis-c-virus-genotype-1-2-4-5-or-6-infection-in-adults-with-compensated-cirrhosis-expedition-1-a-single-arm-open-label-multicentre-phase-3-trial
#15
Xavier Forns, Samuel S Lee, Joaquin Valdes, Sabela Lens, Reem Ghalib, Humberto Aguilar, Franco Felizarta, Tarek Hassanein, Holger Hinrichsen, Diego Rincon, Rosa Morillas, Stefan Zeuzem, Yves Horsmans, David R Nelson, Yao Yu, Preethi Krishnan, Chih-Wei Lin, Jens J Kort, Federico J Mensa
BACKGROUND: The once-daily, ribavirin-free, pangenotypic, direct-acting antiviral regimen, glecaprevir coformulated with pibrentasvir, has shown high rates of sustained virological response in phase 2 and 3 studies. We aimed to assess the efficacy and safety of 12 weeks of coformulated glecaprevir and pibrentasvir in patients with hepatitis C virus (HCV) infection and compensated cirrhosis. METHODS: We did this single-arm, open-label, multicentre phase 3 study at 40 sites in Belgium, Canada, Germany, South Africa, Spain, and the USA...
August 14, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28818250/bars-nightclubs-and-cancer-prevention-new-approaches-to-reduce-young-adult-cigarette-smoking
#16
Pamela M Ling, Louisa M Holmes, Jeffrey W Jordan, Nadra E Lisha, Kirsten Bibbins-Domingo
INTRODUCTION: Tobacco contributes to multiple cancers, and it is largely preventable. As overall smoking prevalence in California declines, smoking has become concentrated among high-risk groups. Targeting social/cultural groups (i.e., "peer crowds") that share common values, aspirations, and activities in social venues like bars and nightclubs may reach high-risk young adult smokers. Lack of population data on young adult peer crowds limits the ability to assess the potential reach of such interventions...
September 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28818053/the-impact-of-self-interviews-on-response-patterns-for-sensitive-topics-a-randomized-trial-of-electronic-delivery-methods-for-a-sexual-behaviour-questionnaire-in-rural-south-africa
#17
Guy Harling, Dumile Gumede, Tinofa Mutevedzi, Nuala McGrath, Janet Seeley, Deenan Pillay, Till W Bärnighausen, Abraham J Herbst
BACKGROUND: Self-interviews, where the respondent rather than the interviewer enters answers to questions, have been proposed as a way to reduce social desirability bias associated with interviewer-led interviews. Computer-assisted self-interviews (CASI) are commonly proposed since the computer programme can guide respondents; however they require both language and computer literacy. We evaluated the feasibility and acceptability of using electronic methods to administer quantitative sexual behaviour questionnaires in the Somkhele demographic surveillance area (DSA) in rural KwaZulu-Natal, South Africa...
August 17, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28818019/pembrolizumab-in-the-treatment-of-metastatic-non-small-cell-lung-cancer-a-review-of-current-evidence
#18
Karim Rihawi, Francesco Gelsomino, Francesca Sperandi, Barbara Melotti, Michelangelo Fiorentino, Laura Casolari, Andrea Ardizzoni
Immune checkpoint inhibitors (ICPIs) are considered one of the most important breakthroughs in cancer treatment of the past decade; notably, different studies of programmed cell death protein 1 (PD-1) and programmed death-ligand 1 (PD-L1) inhibitors have reported impressive clinical activity and durable responses in patients with advanced non-small cell lung cancer (NSCLC). These findings have led to the changing of the current therapeutic algorithm of advanced NSCLC, adding a new standard first-line treatment option for patients with PD-L1-positive tumors...
August 1, 2017: Therapeutic Advances in Respiratory Disease
https://www.readbyqxmd.com/read/28817806/specialized-mechanosensory-nociceptors-mediating-rapid-responses-to-hair-pull
#19
Nima Ghitani, Arnab Barik, Marcin Szczot, James H Thompson, Chia Li, Claire E Le Pichon, Michael J Krashes, Alexander T Chesler
The somatosensory system provides animals with the ability to detect, distinguish, and respond to diverse thermal, mechanical, and irritating stimuli. While there has been progress in defining classes of neurons underlying temperature sensation and gentle touch, less is known about the neurons specific for mechanical pain. Here, we use in vivo functional imaging to identify a class of cutaneous sensory neurons that are selectively activated by high-threshold mechanical stimulation (HTMRs). We show that their optogenetic excitation evokes rapid protective and avoidance behaviors...
August 16, 2017: Neuron
https://www.readbyqxmd.com/read/28817783/the-association-between-insurance-type-and-cost-related-delay-in-care-a-survey
#20
Sora Al Rowas, Michael B Rothberg, Benjamin Johnson, Joel Miller, Mohanad AlMahmoud, Jennifer Friderici, Sarah L Goff, Tara Lagu
OBJECTIVES: Massachusetts has insurance rates similar to those projected under the Affordable Care Act, but many of the state's patients are insured through private insurance plans with high out-of-pocket costs. We aimed to explore the relationship between insurance type (private vs public) and delays in care due to cost, stratified by income. STUDY DESIGN: Cross-sectional study. METHODS: We conducted a study of English-speaking adults recruited from the waiting rooms of the emergency department or outpatient clinics of a large healthcare system in western Massachusetts...
July 2017: American Journal of Managed Care
keyword
keyword
22402
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"