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https://www.readbyqxmd.com/read/29143943/the-impact-of-ejaculatory-abstinence-on-semen-analysis-parameters-a-systematic-review
#1
REVIEW
Brent M Hanson, Kenneth I Aston, Tim G Jenkins, Douglas T Carrell, James M Hotaling
OBJECTIVE: The aim of this study was to evaluate recent publications and determine the impact of ejaculatory abstinence on semen analysis parameters as well as fertility outcomes. METHODS: This was a systematic review of 28 recent publications. The focus of this study was the impact of abstinence on semen parameters and fertility outcomes in papers published since the year 2000. The specific parameters evaluated were volume, sperm count, motility, morphology, pH, DNA fragmentation rate, viability, and pregnancy or fertilization rates following assisted reproduction...
November 16, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29142452/infertility-stress-in-couples-undergoing-intrauterine-insemination-and-in-vitro-fertilization-treatments
#2
Manisha Awtani, Kamayani Mathur, Sandeep Shah, Manish Banker
Aim: The main aim of the study was to assess the stress levels of husbands and wives undergoing intrauterine insemination (IUI) and in vitro fertilization (IVF) treatments, and also to observe whether the stress levels differed between the methods of treatments. Materials and Methods: This research focused on 120 infertile couples who underwent IUI and In Vitro Fertilization-Intra Sperm Cytoplasmic sperm Injection (IVF-ICSI) at an infertility clinic from April 2014 to November 2014...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29142445/a-study-of-controlled-ovarian-stimulation-with-clomiphene-citrate-or-letrozole-in-combination-with-gonadotropins-and-iui-in-unexplained-infertility
#3
Madhusmita Hembram, Ratna Biswas, Anju Jain
Aim: To compare the effect of clomiphene citrate (CC) + human menopausal gonadotropin (hMG) with letrozole + hMG on size, number of follicles, endometrial thickness, serum levels of oestradiol and progesterone and pregnancy rate. Settings and Design: Non-randomised interventional study. Patients and Methods: A total number of 60 patients in the age group of 20-35 years with unexplained infertility were divided into two groups, 30 in each. Group A received CC + hMG and group B received letrozole + hMG...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29129781/effect-of-sperm-morphology-on-pregnancy-success-via-intrauterine-insemination-a-systematic-review-and-meta-analysis
#4
Taylor P Kohn, Jaden R Kohn, Ranjith Ramasamy
PURPOSE: Men with abnormal sperm morphology are often counseled that natural conception and intrauterine insemination are ineffective and that in vitro fertilization is the only option. Our objective is to determine the effect of sperm morphology on pregnancy success with intrauterine insemination (IUI). MATERIALS AND METHODS: We systematically searched for studies published prior to January 2017 that 1) reported ultrasound-verified clinical pregnancies per IUI cycle; 2) assessed sperm morphology using the Strict Criteria; and 3) reported morphology at the >4% and ≤4% and/or ≥1% and <1% thresholds...
November 9, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29117383/assisted-reproductive-technology-in-europe-2013-results-generated-from-european-registers-by-eshre
#5
C Calhaz-Jorge, C De Geyter, M S Kupka, J de Mouzon, K Erb, E Mocanu, T Motrenko, G Scaravelli, C Wyns, V Goossens
STUDY QUESTION: Are there any changes in the treatments involving ART and IUI initiated in Europe during 2013 compared with previous years? SUMMARY ANSWER: An increase in the overall number of ART cycles resulting from a higher number of countries reporting data was evident, the pregnancy rates (PRs) in 2013 remained stable compared with those reported in 2012, the number of transfers with multiple embryos (3+) was lower than ever before yet the multiple delivery rates (DRs) remained unchanged, and IUI activity and success rates were similar to those of last years...
October 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29078018/cervical-mucus-removal-prior-to-intrauterine-insemination-a-randomized-trial
#6
Mohammad Ahmed Maher, Tarek Mohammad Sayyed, Nabih Elkhouly
OBJECTIVE: To detect if removing the cervical mucus before performing intrauterine insemination (IUI) could improve pregnancy outcomes in patients with unexplained infertility. DESIGN: Prospective randomized study. SETTING: An Egyptian University Hospital. POPULATION: Seven hundred fourteen couples with unexplained infertility who underwent intrauterine insemination (IUI) with or without cervical mucus removal. METHODS: Patients were randomly allocated using computer-generated numbers into cervical mucus removal (removed from both internal and external os) or a non-mucus removal groups...
October 27, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29066016/the-impact-of-access-barriers-on-fertility-treatment-decision-making-a-qualitative-study-from-the-perspectives-of-patients-and-service-providers
#7
Erika Maxwell, Maria Mathews, Shree Mulay
OBJECTIVE: The purpose of this study was to explore how barriers to accessing fertility services affect the treatment decisions made by fertility patients and service providers in Newfoundland and Labrador. METHODS: Semistructured, in-depth interviews were conducted with 11 patients across Newfoundland and with eight service providers from Newfoundland and Labrador Fertility Services (located in St. John's) to gather the perspectives of both patients and providers...
October 20, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29062796/controlled-ovarian-hyperstimulation-with-intrauterine-insemination-is-more-successful-after-r-hcg-administration-than-spontaneous-lh-surge
#8
Evan Taerk, Edward Hughes, Cassandra Greenberg, Michael Neal, Shilpa Amin, Mehrnoosh Faghih, Megan Karnis
BACKGROUND: The purpose of this study was to evaluate whether clinical pregnancy rate is affected by timing intrauterine insemination (IUI) according to serum LH surge, r-hCG trigger, or a combination of LH surge and r-hCG trigger in controlled ovarian hyperstimulation (COH) cycles for patients with a variety of infertility etiologies. METHODS: The last 365 consecutive COH-IUI cycles performed at ONE Fertility Burlington in 2014 were reviewed and categorized according to method of IUI timing...
July 2017: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/29051002/men-with-severe-oligospermia-appear-to-benefit-from-varicocele-repair-a-cost-effectiveness-analysis-of-assisted-reproductive-technology
#9
Justin M Dubin, Aubrey B Greer, Taylor P Kohn, Thomas A Masterson, Lunan Ji, Ranjith Ramasamy
OBJECTIVE: To evaluate the outcomes of men who underwent varicocelectomy for TMSC < 2 million and to perform a cost effectiveness analysis of IUI and IVF/ICSI after varicocelectomy. METHODS: We prospectively collected data of men with TMSC less than 2 million who underwent microsurgical subinguinal varicocelectomy. Men with azoospermia were excluded. Serum testosterone, luteinizing hormone, and follicle stimulating hormone were measured pre-operatively. Post-operative semen analysis was collected first at 3 months and then every 3 months thereafter...
October 16, 2017: Urology
https://www.readbyqxmd.com/read/29043705/quality-of-life-and-its-influencing-factors-of-couples-referred-to-an-infertility-center-in-shiraz-iran
#10
Bahia Namavar Jahromi, Mahsa Mansouri, Sedighe Forouhari, Tahere Poordast, Alireza Salehi
Background: Infertility adversely affects quality of life (QoL). The present study aims to evaluate QoL and its associated factors among infertile couples. MATERIALS AND METHODS: In this cross-sectional study, the Fertility QoL (FertiQoL) instrument was used to measure QoL among 501 volunteer couples who attended the Infertility Clinic at the Mother and Child Hospital, Shiraz, Iran. We used an additional questionnaire to assess participants' demographic and clinical characteristics...
January 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29040538/immobilization-or-mobilization-after-iui-an-rct
#11
J van Rijswijk, M R Caanen, V Mijatovic, C G Vergouw, P M van de Ven, C B Lambalk, R Schats
STUDY QUESTION: Does 15 min of immobilization after IUI improve pregnancy rates? SUMMARY ANSWER: Immobilization for 15 min after IUI does not improve pregnancy rates. WHAT IS KNOWN ALREADY: Prior RCTs report a beneficial effect of supine immobilization for 15 min following IUI compared to immediate mobilization, however, these studies can be criticized. Given the importance for the logistics in daily practice and the lack of biological plausibility we planned a replication study prior to potential implementation of this procedure...
November 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29021901/icsi-diagnostic-a-way-to-prevent-total-fertilization-failure-after-4-unsuccessful-iui
#12
Arnaud Larbuisson, Dominique Raick, Stephanie Demelenne, Annick Delvigne
BACKGROUND: The aim of this retrospective study is to investigate the relevance of dividing oocytes and using some for traditional in vitro fertilization (IVF) and others for intracytoplasmic sperm injection (ICSI) as of the first IVF cycle in patients with unexplained infertility who have undergone 4 intrauterine insemination (IUI) cycles which produced no pregnancies. METHODS: This retrospective study includes patients with unexplained infertility who have failed to become pregnant, after 4 IUI, despite normal semen parameters after sperm capacitation...
2017: Basic and Clinical Andrology
https://www.readbyqxmd.com/read/28982170/a-combined-transcriptome-and-proteome-analysis-extends-the-allergome-of-house-dust-mite-dermatophagoides-species
#13
Véronique Bordas-Le Floch, Maxime Le Mignon, Laetitia Bussières, Karine Jain, Armelle Martelet, Véronique Baron-Bodo, Emmanuel Nony, Laurent Mascarell, Philippe Moingeon
BACKGROUND: House dust mites (HDMs) such as Dermatophagoides farinae and D. pteronyssinus represent major causes of perennial allergy. HDM proteomes are currently poorly characterized, with information mostly restricted to allergens. As of today, 33 distinct allergen groups have been identified for these 2 mite species, with groups 1 and 2 established as major allergens. Given the multiplicity of IgE-reactive mite proteins, potential additional allergens have likely been overlooked. OBJECTIVE: To perform a comprehensive characterization of the transcriptomes, proteomes and allergomes of D...
2017: PloS One
https://www.readbyqxmd.com/read/28942518/projecting-the-potential-impact-of-the-cap-score%C3%A2-on-clinical-pregnancy-live-births-and-medical-costs-in-couples-with-unexplained-infertility
#14
Joseph B Babigumira, Fady I Sharara, Louis P Garrison
PURPOSE: The Cap-Score™ was developed to assess the capacitation status of men, thereby enabling personalized management of unexplained infertility by choosing timed intrauterine insemination (IUI), versus immediate in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) in individuals with a low Cap-Score™. The objective of this study was to estimate the differences in outcomes and costs comparing the use of the Cap-Score™ with timed IUI (CS-TI) and the standard of care (SOC), which was assumed to be three IUI cycles followed by three IVF-ICSI cycles...
September 23, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28941161/from-clinical-observations-and-molecular-dissection-to-novel-therapeutic-strategies-for-primary-immunodeficiency-disorders
#15
REVIEW
Hans D Ochs, Daniel Petroni
The field of primary immunodeficiency diseases (PID) is rapidly expanding with more than 300 genetically defined disorders that have been clinically described and molecularly analyzed. The molecular dissection of these entities has led to the discovery of new immunologic pathways and to novel and effective disease-specific therapies. This review provides a summary of these primary immune defects categorized by clinical phenotype and molecular similarity as defined by the International Union of Immunologic Societies (IUIS) Expert Committee for PID...
September 21, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28938746/women-s-career-priority-is-associated-with-attitudes-towards-family-planning-and-ethical-acceptance-of-reproductive-technologies
#16
Michael K Simoni, Lin Mu, Stephen C Collins
STUDY QUESTION: Do women who place high importance on career success have different perceptions of pregnancy planning, delayed reproduction, and the ethical acceptability of ART than women with less emphasis on their career? SUMMARY ANSWER: Career-focused women place more importance on pregnancy planning, have greater confidence in delayed childbearing, and are more ethically accepting of donor gamete ART than women who do not place as much importance on career success...
October 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28933569/day-two-post-retrieval-1500-iui-hcg-bolus-progesterone-free-luteal-support-post-gnrh-agonist-trigger-a-proof-of-concept-study
#17
Sharon Vanetik, Linoy Segal, Tatiana Breizman, Shahar Kol
Small dose of hCG (1500 IU) on the day of oocyte retrieval, followed by daily progesterone administration, is currently the preferred way to secure adequate luteal support following GnRH agonist trigger. In the current proof-of-concept study, we explored the possibility that a bolus of 1500 IU hCG, given two days after oocyte retrieval, may be sufficient to sustain adequate luteal support without additional progesterone treatment. From February 2015 to August 2016, we obtained 44 pregnancies following GnRHa trigger followed by day 2 hCG (1500 IU) support only (study group)...
September 21, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28932299/the-outcome-of-assisted-reproductive-techniques-among-couples-with-male-factors-at-prince-khalid-bin-sultan-fertility-centre-kingdom-of-saudi-arabia
#18
Hytham Bahaeldin Mukhtar, Amani Shaman, Hyder Osman Mirghani, Ayman Adnan Almasalmah
BACKGROUND: Thirty-three percent of infertility due to paternal factors, there are an increasing proportion of couples who decide to conceive by assisted reproductive techniques (ART). The outcome prediction is pivotal for decision making. AIM: We aimed to study the pregnancy outcomes of different ART with male factors infertility. METHODS: This is retrospective cross-sectional study conducted at Tabuk, Kingdom of Saudi Arabia. One hundred fifteen patients' records reviewed using a structured checklist to collect demographic data, sperm (concentration, motility, and morphology)...
August 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28923283/longer-time-interval-between-semen-processing-and-intrauterine-insemination-does-not-affect-pregnancy-outcome
#19
Charlotte H J R Jansen, Marc G L M Elisen, Cor W Leenstra, Eugenie M Kaaijk, Karlijn J van Stralen, Harold R Verhoeve
OBJECTIVE: To study whether the pregnancy outcome of intrauterine insemination (IUI) is affected by a longer time interval between semen processing and insemination. DESIGN: Retrospective cohort. SETTING: Teaching hospital. PATIENT(S): Couples with subfertility and an indication for IUI over a 10-year period. INTERVENTION (S): Insemination performed the day after but within 24 hours of semen collection and processing (delayed insemination) compared with insemination performed immediately after sperm collection and processing (immediate insemination)...
November 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28911932/varicocelectomy-to-upgrade-semen-quality-to-allow-couples-to-use-less-invasive-forms-of-assisted-reproductive-technology
#20
Mary K Samplaski, Kirk C Lo, Ethan D Grober, Armand Zini, Keith A Jarvi
OBJECTIVE: To determine the magnitude of improvement in semen parameters after a varicocelectomy and the fraction that have improvements such that couples needing IVF or IUI are "upgraded" to needing less invasive assisted reproductive technology (ART). DESIGN: Retrospective review of prospectively collected data. SETTING: Academic medical centers. PATIENT(S): Men presenting for a fertility evaluation with a clinical varicocele...
October 2017: Fertility and Sterility
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