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JOURNAL ARTICLE
Nasrin Saharkhiz, Saghar Salehpoor, Sedigheh Hosseini, Leila Nazari, Samaneh Sheibani, Tahereh Doohandeh
BACKGROUND: Various protocols have been approved to improve the response rate leading to successful fertilization in poor ovarian responders (PORs). The application of double ovarian stimulation (DuoStim) in the follicular and luteal phases of the same ovarian cycle has been shown as an intriguing option to achieve more oocyte retrievals in the shortest time. The aim of the current study is to compare the outcomes of different protocols, minimal stimulation (MS) and Duostim. MATERIALS AND METHODS: This randomized clinical trial was performed on 42 in vitro fertilization (IVF) candidates with POR diagnosis...
February 2, 2024: International Journal of Fertility & Sterility
#22
JOURNAL ARTICLE
Khalid Mahmood, Aijaz Ali Channa, Aamir Ghafoor, Amjad Riaz
Equine embryo transfer (EET) is a prominent technology in the equine breeding industry, and its efficacy is affected by a number of factors. The current study aimed to determine the effects of the breed of donor/recipient mares, estrus/ovulation induction treatment, cooled transportation of embryos, and synchrony between donor and recipient mares on the efficiency of the EET under subtropical conditions of Pakistan. A total of eighty-four (n = 84) Polo-playing donor mares (Argentino-polo = 41 and Anglo-Arab = 43) and seventy (n = 70) recipient mares (light breed = 26 and heavy breed = 44) were used for EET...
2024: PloS One
#23
JOURNAL ARTICLE
Chang-Fa Sun, Jian-Zhong Sheng, He-Feng Huang
BACKGROUND: Assisted reproductive technology (ART) has been reported to have negative effects on maternal and neonatal health. Ovulation induction (OI) was reported to be associated with alteration of epigenetic modification of mice embryos, and extinguishing the influence of ovulation induction and in vitro operations on maternal and neonatal health will bring benefits for reducing side effects. The present study aimed to determine whether ovulation induction alone and ART are associated with adverse pregnancy outcomes and whether ART could induce a higher risk than ovulation induction alone...
2024: Frontiers in Endocrinology
#24
Charlotte Sonigo, Geoffroy Robin, Florence Boitrelle, Eloïse Fraison, Nathalie Sermondade, Emmanuelle Mathieu d' Argent, Pierre-Emmanuel Bouet, Charlotte Dupont, Hélène Creux, Maeliss Peigné, Olivier Pirrello, Sabine Trombert, Emmanuel Lecorche, Ludivine Dion, Laurence Rocher, Emmanuel Arama, Valérie Bernard, Margaux Monnet, Laura Miquel, Eva Birsal, Stéphanie Haïm Boukobza, Ingrid Plotton, Célia Ravel, Véronika Grzegorczyk Martin, Eric Huyghe, Hugo G A Dupuis, Tiphaine Lefevre, Florence Leperlier, Léna Bardet, Imane Lalami, Camille Robin, Virginie Simon, Laura Dijols, Justine Riss, Antoine Koch, Clément Bailly, Constance Rio, Marine Lebret, Margaux Jegaden, Hervé Fernandez, Jean-Luc Pouly, Antoine Torre, Jean-Marie Antoine, Blandine Courbiere
OBJECTIVE: To update the 2010 CNGOF clinical practice guidelines for the first-line management of infertile couples. MATERIALS AND METHODS: Five major themes (first-line assessment of the infertile woman, first-line assessment of the infertile man, prevention of exposure to environmental factors, initial management using ovulation induction regimens, first-line reproductive surgery) were identified, enabling 28 questions to be formulated using the PICO (Patients, Intervention, Comparison, Outcome) format...
February 2, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
#25
JOURNAL ARTICLE
Jie Li, Sien Mo, Zhong Lin, Fuhua Mo, Qiuling Shi
PURPOSE: Our study aimed to investigate the best time to manage hydrosalpinx to improve pregnancy outcomes during in vitro fertilization-embryo transfer (IVF-ET). METHODS: Patients with hydrosalpinx who received IVF treatment were analyzed retrospectively. And two groups were included to compare the effects of different timing treatment of hydrosalpinx on IVF pregnancy outcomes, "Proximal Tubal Occlusion First Group" (Group Ligation-COH) and "Oocyte Retrieval First Group" (Group COH-Ligation)...
February 3, 2024: Archives of Gynecology and Obstetrics
#26
JOURNAL ARTICLE
Hailun Liu, André Franken, Alexandra P Bielfeld, Tanja Fehm, Dieter Niederacher, Zhongping Cheng, Hans Neubauer, Nadia Stamm
BACKGROUND: Decidualization of endometrial cells is the prerequisite for embryo implantation and subsequent placenta formation and is induced by rising progesterone levels following ovulation. One of the hormone receptors contributing to endometrial homeostasis is Progesterone Receptor Membrane Component 1 (PGRMC1), a non-classical membrane-bound progesterone receptor with yet unclear function. In this study, we aimed to investigate how PGRMC1 contributes to human decidualization. METHODS: We first analyzed PGRMC1 expression profile during a regular menstrual cycle in RNA-sequencing datasets...
February 3, 2024: Reproductive Biology and Endocrinology: RB&E
#27
JOURNAL ARTICLE
Laura G Cooney, Mary D Sammel, Iris Lee, M Alexa Clapp, Michelle Goldsammler, Erin Scott, Sarah Bjorkman, Brian T Fisher, Anuja Dokras
OBJECTIVE: To derive and internally validate a clinical prediction model for live birth (LB) in women with polycystic ovary syndrome (PCOS) undergoing in vitro fertilization (IVF). DESIGN: Retrospective cohort study. SETTING: Four academic reproductive endocrinology clinics. PATIENTS: A total of 207 women with PCOS confirmed using Rotterdam criteria undergoing their first fresh IVF cycle. INTERVENTIONS: Not applicable...
February 1, 2024: Fertility and Sterility
#28
JOURNAL ARTICLE
José Nélio de Sousa Sales, Matheus Pedroso Vicente, Laís Reis Carvalho, Lucas Araújo Lemos, Luiz Manoel Souza Simões, Marcos Henrique Alcantara Colli, Walter Antônio Gonçales Junior, Henderson Ayres, Lais Mendes Vieira, Rodolfo Daniel Mingoti, João Paulo Barbuio
The objective of the present study was to evaluate the effect of estradiol valerate administered at the beginning of the ovulation synchronization protocol on the pregnancy rate of Bos indicus cows. In the experiments, the following products from MSD, Sao Paulo, Brazil were used: estradiol valerate (EV), estradiol benzoate (EB), intravaginal progesterone device (P4), estradiol cypionate (EC), equine chorionic gonadotropin (eCG) and cloprostenol (PGF). In Experiment 1, Bos indicus cows (n=899) with a body condition score (BCS) of 2...
January 26, 2024: Theriogenology
#29
Abduljaleel Ethy Ahammedunni, Nadine Borhan Mahmoud Nour, Muhammad Sharif Allah Dad
Cesarean section in a mother with a sextuplet pregnancy is challenging for an anesthesiologist. Several perioperative complications are likely because of the overdistended uterus and associated changes in the mother. We are reporting the case of a woman with a sextuplet pregnancy who came for an emergency cesarean. She also had a background history of polycystic ovarian syndrome (PCOS) and ovulation induction for conception. Early pregnancy was complicated by ovarian hyperstimulation syndrome. She required cervical cerclage in early pregnancy...
January 2024: Curēus
#30
JOURNAL ARTICLE
Adela Rodríguez-Fuentes, Jairo Hernández, Jean Paul Rouleau, Pablo Martín-Vasallo, Angela Palumbo
OBJECTIVE: To determine the minimum follicular volume on the day of trigger that will correspond to a mature oocyte at egg retrieval by individualized follicular puncture and to calculate the mean follicular growth from ovulation induction to egg retrieval by SonoAVC™follicle. DESIGN: Prospective observational study of 53 women undergoing IVF, in which it was possible to identify unequivocally one or more follicles at trigger and at egg retrieval by three-dimensional ultrasound...
January 29, 2024: Fertility and Sterility
#31
JOURNAL ARTICLE
Juan Castillo, Shahar Kol
PURPOSE OF REVIEW: This review aims to compare evidence on four criteria (embryo implantation, obstetric outcomes, patient convenience, and IVF-unit efficiency) by analyzing published research on different endometrial preparation methods for frozen embryo transfer (FET). RECENT FINDINGS: While the artificial-FET cycle provides advantages in scheduling and implantation, it falls short in ensuring optimal obstetric outcomes. In contrast, natural-FET ensures embryo implantation conditions if ovulation is correctly identified...
February 1, 2024: Current Opinion in Obstetrics & Gynecology
#32
JOURNAL ARTICLE
Md Rezanujjaman, Theeranukul Pachoensuk, Md Forhad Hossain, Md Maisum Sarwar Jyoti, Md Rubel Rana, Eisei Tsutsumi, Takumi Mouri, Maria Bramastri Susilo, Klangnurak Wanlada, Chihiro Yamamoto, Md Hasan Ali, Toshinobu Tokumoto
The prss59.1 gene was identified as one of 11 genes that were highly upregulated during the induction of ovulation in zebrafish by using an in vivo ovulation assay. Previously, we conducted biochemical characterization of Prss59.1 and revealed it to be a trypsin-like proteolytic enzyme. In this study, we established a prss59.1 gene knockout strain using the CRISPR/Cas9 system. Phenotypic analysis of prss59.1 knockout fish showed that prss59.1 is associated with chorion elevation, a prominent event in egg activation during fertilization...
January 26, 2024: General and Comparative Endocrinology
#33
REVIEW
Saeed Baradwan, Faisal Al-Shalhoub, Majed Saeed Alshahrani, Samah Himayda, Rayan AlSghan, Hussein Sabban, Inass Hassan Ahmad, Marwa Fekry Mohamed El Sayed, Entesar Omar Mohamad, Abdulhadi A AlAmodi, Ahmed Mohamed Abdelhakim, Kareem Shaheen
OBJECTIVE: To compare letrozole in combination with gonadotropins versus letrozole monotherapy in ovulation induction and clinical pregnancy among infertile women with polycystic ovarian syndrome (PCOS). METHODS: Several databases were searched for available clinical trials from inception until March 2023. We selected randomized controlled trials (RCTs) that compared sequential letrozole/gonadotropin versus letrozole alone among infertile women who met the Rotterdam criteria for PCOS...
January 27, 2024: Hormones: International Journal of Endocrinology and Metabolism
#34
JOURNAL ARTICLE
M L Johannsen, L C Poulsen, L S Mamsen, M L Grøndahl, A L M Englund, N L Lauritsen, E C Carstensen, B Styrishave, C Yding Andersen
STUDY QUESTION: What is the temporal activity and the concentration in follicular fluid (FF) of the anti-inflammatory steroid cortisol during the ovulatory process in humans? SUMMARY ANSWER: Intrafollicular concentrations of cortisol become massively upregulated close to ovulation concomitant with an exceptionally high biological activity securing a timely and efficient termination of inflammatory processes. WHAT IS KNOWN ALREADY: Ovulation has been described as a local, controlled inflammatory process resulting in the degeneration of the follicle wall which facilitate oocyte extrusion...
January 24, 2024: Human Reproduction
#35
JOURNAL ARTICLE
J G Hamze, P Peris-Frau, B Galiano-Cogolludo, C Tomás-Almenar, J Santiago-Moreno, P Bermejo-Álvarez
Rabbits constitute an interesting model to understand gamete interaction and test novel Artificial Reproductive Techniques, but in vitro fertilization (IVF) is particularly problematic in this species. We have conducted a series of experiments to develop a consistent IVF technique. Initially, we checked viability, acrosome integrity, capacitation and motility in ejaculated sperm purified by a density gradient and incubated at different times in three different media: Tyrode's Albumin Lactate Pyruvate (TALP), human tubal fluid (HTF), and Brackett and Oliphant (BO)...
January 9, 2024: Theriogenology
#36
JOURNAL ARTICLE
Eli Y Adashi, Alan S Penzias, Philip A Gruppuso, Aniket D Kulkarni, Yujia Zhang, Dmitry M Kissin, Roee Gutman
OBJECTIVE: To study the contribution of ovulation induction and ovarian stimulation, in vitro fertilization (IVF), and unassisted conception to the increase in national plural births in the United States, a significant contributor to adverse maternal and infant health outcomes. DESIGN: National and IVF-assisted plural birth data were derived from the Centers for Disease Control and Prevention's National Vital Statistics System (1967-2021, after introduction of Clomiphene Citrate in the United States) and the National Assisted Reproductive Technology Surveillance System (1997-2021), respectively...
January 19, 2024: Fertility and Sterility
#37
Mariana Guerra, Daniela Marado, Fátima Silva, Maria Céu Almeida
BACKGROUND: Ovarian hyperstimulation syndrome (OHSS) is a rare ovulation induction therapy side effect. Nevertheless, it can occur in spontaneous ovulation cycles linked to multiple gestation, molar pregnancy, polycystic ovarian syndrome, and hypothyroidism. The pathogenesis of OHSS remains poorly understood. However, in recent studies, it has been observed that increased concentrations of thyroid-stimulating hormone (TSH) can potentially have stimulatory effects on the ovaries due to the homologous structure shared between TSH and gonadotropins...
2024: AME Case Reports
#38
JOURNAL ARTICLE
Paula Almeida Galvão Ferreira, Luiz Augusto Giordano, Luiz Felipe Bittencourt
OBJECTIVE: To evaluate the efficacy of sublingually administered human chorionic gonadotropin (HCG) in combination with clomiphene citrate (CC) or letrozole (LTZ) for ovulation induction. METHODS: In this prospective, double-blind, randomized study, the patients were divided into two placebo groups and two intervention groups using CC, LTZ, and HCG. RESULTS: There were no statistically significant differences in ovulation induction between the groups...
January 15, 2024: JBRA Assisted Reproduction
#39
JOURNAL ARTICLE
Lingling Wu, Fenfang Su, Peixin Luo, Qingqing Dong, Mengni Ma, Guangyong Ye
BACKGROUND: Platelet-rich plasma (PRP) is a therapeutic approach that is gaining attention for its potential in the treatment of poor ovarian response. This meta-analysis aimed to systematically review and analyze clinical studies to evaluate the impact of PRP on poor responders undergoing ovarian stimulation for IVF. METHODS: A comprehensive search was conducted in electronic databases, including PubMed, Embase, Scopus, Web of Science, and the Cochrane Library to identify relevant studies published in English...
December 2024: Platelets
#40
JOURNAL ARTICLE
Simon Azubuike Ubah, Samson Eneojo Abalaka, Victory Clara Asibor, Ebenezer Kehinde Ogundana, Itodo Joy Iyojo, Oluwa Adikpe Agbonu, Philemon Kwinjoh Columbus, Kenneth Owoicho Abah, Christopher Ese Obudu, Oluwatobi Akefe Isaac, Prisca Adaoma Ezinwo
BACKGROUND: The pituitary glands normally produce and stores gonadotropic hormones (GnH) that are responsible for ovulation and spermiation in animals. However, whether fish pituitary extracts can elicit same effects in treated animals need elucidation as a prelude to their practical usage in animals. OBJECTIVES: The aim of this study was to investigate the oestrus-inducing potential of the pituitary gland extract of the Africa Catfish ( Clarias gariepinus ) in immature Wistar rats...
2024: Recent Patents on Biotechnology
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