Kendra R Sylvester-Armstrong, Callie F Reeder, Andrece Powell, Matthew W Becker, D Walker Hagan, Jing Chen, Clayton E Mathews, Clive H Wasserfall, Mark A Atkinson, Robert Egerman, Edward A Phelps
Pancreatic beta cells are among the slowest replicating cells in the human body and have not been observed to increase in number except during the fetal and neonatal period, in cases of obesity, during puberty, as well as during pregnancy. Pregnancy is associated with increased beta cell mass to meet heightened insulin demands. This phenomenon raises the intriguing possibility that factors present in the serum of pregnant individuals may stimulate beta cell proliferation and offer insights into expansion of the beta cell mass for treatment and prevention of diabetes...
December 31, 2024: Islets