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Diet chronic kidney disease

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https://www.readbyqxmd.com/read/29324762/obesogenic-diets-alter-metabolism-in-mice
#1
Megan R Showalter, Eric B Nonnecke, A L Linderholm, Tomas Cajka, Michael R Sa, Bo Lönnerdal, Nicholas J Kenyon, Oliver Fiehn
Obesity and accompanying metabolic disease is negatively correlated with lung health yet the exact mechanisms by which obesity affects the lung are not well characterized. Since obesity is associated with lung diseases as chronic bronchitis and asthma, we designed a series of experiments to measure changes in lung metabolism in mice fed obesogenic diets. Mice were fed either control or high fat/sugar diet (45%kcal fat/17%kcal sucrose), or very high fat diet (60%kcal fat/7% sucrose) for 150 days. We performed untargeted metabolomics by GC-TOFMS and HILIC-QTOFMS and lipidomics by RPLC-QTOFMS to reveal global changes in lung metabolism resulting from obesity and diet composition...
2018: PloS One
https://www.readbyqxmd.com/read/29324682/malnutrition-inflammation-atherosclerosis-syndrome-mia-and-diet-recommendations-among-end-stage-renal-disease-patients-treated-with-maintenance-hemodialysis
#2
Małgorzata Maraj, Beata Kuśnierz-Cabala, Paulina Dumnicka, Agnieszka Gala-Błądzińska, Katarzyna Gawlik, Dorota Pawlica-Gosiewska, Anna Ząbek-Adamska, Małgorzata Mazur-Laskowska, Piotr Ceranowicz, Marek Kuźniewski
Malnutrition-inflammation-atherosclerosis syndrome is one of the causes of increased mortality in chronic kidney disease (CKD). The aim of the study was to assess the inflammation and nutritional status of patients in end-stage kidney disease treated with maintenance hemodialysis. The study included a group of 98 hemodialyzed patients with stage 5 CKD (38 women and 60 men). Albumin, prealbumin (PRE), and C-reactive protein (CRP) were measured in serum samples collected before mid-week dialysis. Fruit and vegetables frequency intakes were assessed with a questionnaire...
January 11, 2018: Nutrients
https://www.readbyqxmd.com/read/29321950/manifestations-of-renal-impairment-in-fructose-induced-metabolic-syndrome
#3
Kameliya Bratoeva, George S Stoyanov, Albena Merdzhanova, Mariya Radanova
Introduction International studies show an increased incidence of chronic kidney disease (CKD) in patients with metabolic syndrome (MS). It is assumed that the major components of MS - obesity, insulin resistance, dyslipidemia, and hypertension - are linked to renal damage through the systemic release of several pro-inflammatory mediators, such as uric acid (UA), C-reactive protein (CRP), and generalized oxidative stress. The aim of the present study was to investigate the extent of kidney impairment and manifestations of dysfunction in rats with fructose-induced MS...
November 7, 2017: Curēus
https://www.readbyqxmd.com/read/29321218/non-uniform-relationship-between-salt-status-and-aldosterone-activity-in-patients-with-chronic-kidney-disease
#4
Alison H M Taylor, Alastair J Rankin, Emily P McQuarrie, E Marie Freel, Natalie Z M Homer, Ruth Andrew, Alan G Jardine, Patrick B Mark
BACKGROUND: Hypertension is prevalent in chronic kidney disease (CKD). Studies suggest that reduction in dietary salt intake reduces blood pressure (BP). We studied relationships between salt intake, BP and renin angiotensin system regulation in order to establish if it is disordered in CKD. METHODS: Mechanistic crossover study of CKD patients versus non-CKD controls. Participants underwent modified saline suppression test prior to randomisation to either low or high salt diet for 5 days and then crossed over to the alternate diet...
January 10, 2018: Clinical Science (1979-)
https://www.readbyqxmd.com/read/29319775/primary-hiperoxaluria-diagnosed-after-kidney-transplantation-report-of-2-cases-and-literature-review
#5
John Fredy Nieto Rios, Monica Zuluaga, Lina Maria Serna Higuita, Adriana Florez, Diana Carolina Bello-Marquez, Arbey Aristizábal, Catalina Ocampo Kohn, Gustavo Adolfo Zuluaga
Primary hyperoxaluria (PH) is a very rare genetic disorder; it is characterized by total or partial deficiency of the enzymes related to the metabolism of glyoxylate, with an overproduction of calcium oxalate that is deposited in different organs, mainly the kidney, leading to recurrent lithiasis, nephrocalcinosis and end stage renal disease (ESRD). In patients with ESRD that receive kidney transplantation alone, the disease has a relapse of 100%, with graft loss in a high percentage of patients in the first 5 years of transplantation...
October 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29311039/sodium-reduced-meat-and-poultry-products-contain-a-significant-amount-of-potassium-from-food-additives
#6
Arti Sharma Parpia, Marc B Goldstein, JoAnne Arcand, France Cho, Mary R L'Abbé, Pauline B Darling
BACKGROUND: Sodium-reduced packaged food products are increasingly available to consumers; however, it is not clear whether they are suitable for inclusion in a potassium-reduced diet. For individuals with impaired renal potassium excretion caused by chronic kidney disease and for those taking certain medications that interfere with the rennin-angiotensin aldosterone axis, the need to limit dietary potassium is important in view of the risk for development of hyperkalemia and fatal cardiac arrhythmias...
January 6, 2018: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/29304720/the-effect-of-cholesterol-overload-on-mouse-kidney-and-kidney-derived-cells
#7
Shoko Honzumi, Miho Takeuchi, Mizuki Kurihara, Masachika Fujiyoshi, Masashi Uchida, Kenta Watanabe, Takaaki Suzuki, Itsuko Ishii
INTRODUCTION: Dyslipidemia is one of the onset and risk factors of chronic kidney disease and renal function drop is seen in lipoprotein abnormal animal models. However, the detailed molecular mechanism of renal lipotoxicity has not been clarified. Therefore, the present study aimed to investigate the influence of cholesterol overload using mouse kidney tissue and kidney-derived cultured cells. METHODS: C57BL/6 mice were fed normal diet (ND) or 1.25% cholesterol-containing high-cholesterol diet (HCD) for 11 weeks, and we used megalin as a proximal tubule marker for immunohistology...
November 2018: Renal Failure
https://www.readbyqxmd.com/read/29304096/exogenous-bmp7-in-aortae-of-rats-with-chronic-uremia-ameliorates-expression-of-profibrotic-genes-but-does-not-reverse-established-vascular-calcification
#8
Eva Gravesen, Maria Lerche Mace, Anders Nordholm, Jacob Hofman-Bang, Keith Hruska, Carsten Haagen Nielsen, Andreas Kjær, Klaus Olgaard, Ewa Lewin
Hyperphosphatemia and vascular calcification are frequent complications of chronic renal failure and bone morphogenetic protein 7 (BMP7) has been shown to protect against development of vascular calcification in uremia. The present investigation examined the potential reversibility of established uremic vascular calcification by treatment of uremic rats with BMP7. A control model of isogenic transplantation of a calcified aorta from uremic rats into healthy littermates examined whether normalization of the uremic environment reversed vascular calcification...
2018: PloS One
https://www.readbyqxmd.com/read/29301002/should-we-eat-more-potassium-to-better-control-blood-pressure-in-hypertension
#9
Michel Burnier
Changes in lifestyle and nutrition are recommended as the first-step approach to the management of hypertension by all national and international guidelines. Today, when considering nutritional factors in hypertension, almost all the attention is focused on the reduction of salt intake to improve blood pressure (BP) control. Changes in potassium intake are only briefly evoked in guidelines. Few physicians actually think about proposing to eat more foods that are high in potassium (fruits, vegetables, nuts) to better control BP...
January 2, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29290351/red-meat-intake-in-chronic-kidney-disease-patients-two-sides-of-the-coin
#10
REVIEW
Denise Mafra, Natalia A Borges, Ludmila Ferreira Medeiros de Franca Cardozo, Juliana S Anjos, Ana Paula Black, Cristiane Moraes, Peter Bergman, Bengt Lindholm, Peter Stenvinkel
Red meat is an important dietary source of high biological value protein and micronutrients such as vitamins, iron, and zinc that exert many beneficial functions. However, high consumption of animal protein sources, especially red meat, results in an increased intake of saturated fat, cholesterol, iron, and salt, as well as an excessive acid load. Red meat intake may lead to an elevated production of uremic toxins by the gut microbiota, such as trimethylamine n-oxide (TMAO), indoxyl sulfate, and p-cresyl sulfate...
February 2018: Nutrition
https://www.readbyqxmd.com/read/29287685/medicinal-plants-and-bioactive-natural-compounds-in-the-treatment-of-non-alcoholic-fatty-liver-disease-a-clinical-review
#11
REVIEW
Mohammad Bagherniya, Valerio Nobili, Christopher N Blesso, Amirhossein Sahebkar
Non-alcoholic fatty liver disease (NAFLD) is a major cause of liver diseases, and is closely related to metabolic syndrome and its related conditions, diabetes mellitus and dyslipidemia. On the other hand, NAFLD as a multisystem disease increases the risk of several chronic diseases include type 2 diabetes mellitus, cardiovascular disease (CVD), and chronic kidney disease. The main objective was to review the efficacy of bioactive natural compounds assessed by clinical trials. Search literature using four databases (PubMed, EBSCO, Web of Science, and Ovid Medline) to review publications that focused on the impact of bioactive natural compounds in NAFLD treatment...
December 26, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29285426/cockcroft-gault-modification-of-diet-in-renal-disease-and-chronic-kidney-disease-epidemiology-collaboration-equations-for-estimating-glomerular-filtration-rates-in-cancer-patients-receiving-cisplatin-based-chemotherapy
#12
Jiyoung Rhee, Jung Mi Kwon, Sang Hoon Han, Sun Hyung Kim, Chang Hyun Park, Ji Hyeon Jeon, Jong Tae Cho, Eun Kyoung Lee, So Mi Kim
Background: Although the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation has been recommended for accurate estimates of glomerular filtration rate (eGFR), there is little information regarding differences in GFR estimates obtained using the Cockcroft-Gault (CG) or Modification of Diet in Renal Disease (MDRD) equations in East Asian cancer patients. We investigated discrepancies in GFR and toxicities in patients treated with cisplatin-based chemotherapy using three equations equations...
December 2017: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/29283932/glomerular-filtration-rate-is-unchanged-by-ultramarathon
#13
Wojciech Wołyniec, Wojciech Ratkowski, Katarzyna Kasprowicz, Zbigniew Jastrzębski, Sylwia Małgorzewicz, Konrad Witek, Tomasz Grzywacz, Piotr Żmijewski, Marcin Renke
THE MAIN PROBLEM: Acute kidney injury (AKI) is reported as a common complication of marathon and ultramarathon running. In previous studies AKI was diagnosed on the basis of the creatinine level in serum and estimated glomerular filtration rate (eGFR). In the present study we calculated eGFR and also measured creatinine clearance after every 25 km of a 100 km run. METHODS: 20 healthy, amateur runners (males, mean age 40.75 ± 7.15 years, mean weight 76.87 ± 8.39 kg) took part in a 100 km run on a track...
December 27, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29280657/-assessment-of-diet-in-patients-with-chronic-kidney-diseases-without-dialysis-and-relationship-with-the-nutritional-status
#14
Almudena Pérez Torres, María Elena González García, Ana María López Sobaler, Rafael Jesús Sánchez Villanueva, Rafael Selgas Gutiérrez
BACKGROUND: Diet is one of the pillars of the treatment for patients with chronic kidney disease without dialysis (NDD-CKD). Despite this, very few studies have evaluated the diet in Spanish population. OBJECTIVE: To evaluate the diet of a group of patients with advanced CKD, comparing it with the recommendations, and its relation with nutritional status. MATERIAL AND METHODS: A cross-sectional study of 74 patients (39 men), with a mean age of 70...
October 27, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29249230/full-age-spectrum-equation-may-be-an-alternative-method-to-estimate-the-glomerular-filtration-rate-in-chinese-patients-with-chronic-kidney-disease%C3%A2
#15
Lingxiong Chai, Meifang Wang, Kedan Cai, Qun Luo, Haihong Yi, Jianyong Wu
OBJECTIVE: To assess the performance of the full age spectrum (FAS) equation in comparison to other equations in subjects with chronic kidney disease (CKD) for the first time in China. MATERIALS AND METHODS: The measured glomerular filtration rate (mGFR) obtained by the 99mTc-diethylenetriamine pentaacetic acid renogram was used as the reference standard. Bias, precision, and accuracy were analyzed to identify which of these four equations performed better: FAS equation, the Modification of Diet in Renal Disease (MDRD) equation, the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation and the Berlin Initiative Study-1 (BIS-1) equation...
December 18, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/29238578/bone-eating-kidney-disease
#16
Abhilash Koratala, Muhannad Leghrouz, Amir Kazory
In the current era of early detection of chronic kidney disease and efficient therapeutic options for management of its complications, skeletal manifestations of renal hyperparathyroidism are increasingly rare. A 31-year-old female patient presented for evaluation of severe pain in the left forearm, right hand, right knee, right hip, and lower back following a fall sustained 3 days prior to presentation. She had a history of end-stage renal disease and received maintenance hemodialysis. Review of the medical records revealed that she had poor compliance with her diet, medications, and dialysis treatments...
2017: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29237422/mdrd-vs-ckd-epi-in-comparison-to-51chromium-edta-a-cross-sectional-study-of-malaysian-ckd-cohort
#17
Maisarah Jalalonmuhali, Soo Kun Lim, Mohammad Nazri Md Shah, Kok Peng Ng
BACKGROUND: Accurate measurement of renal function is important: however, radiolabelled gold standard measurement of GFR is highly expensive and can only be used on a very limited scale. We aim to compare the performance of Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equations in the multi-ethnic population attending University Malaya Medical Centre (UMMC). METHODS: This is a cross-sectional study recruiting patients, who attend UMMC Nephrology clinics on voluntary basis...
December 13, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/29223530/diet-quality-of-chronic-kidney-disease-patients-and-the-impact-of-nutritional-counseling
#18
Andréia Silva Fernandes, Christiane Ishikawa Ramos, Fabiana Baggio Nerbass, Lilian Cuppari
OBJECTIVES: The aims of the study were to evaluate the quality of the diet of nondialysis-dependent patients with chronic kidney disease and to investigate the impact of dietary counseling in the quality of the diet of these patients. METHODS: In the cross-sectional analysis, 3-day food records of 100 nondialysis-dependent patients with chronic kidney disease patients, in the first visit to the renal dietitians, were evaluated using the Diet Quality Index (DQI)...
December 6, 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/29221627/alkaline-diet-and-metabolic-acidosis-practical-approaches-to-the-nutritional-management-of-chronic-kidney-disease
#19
Larissa Rodrigues Neto Angéloco, Gabriela Cristina Arces de Souza, Elen Almeida Romão, Paula Garcia Chiarello
The kidneys play an extremely important role in maintaining the body acid-base balance by excreting nonvolatile acids and regenerating and reabsorbing bicarbonate in the kidney tubules. As the individual loses their kidney function, renal excretion of nonvolatile acid produced by metabolism of the diet is impaired, resulting in low-grade metabolic acidosis. With this in mind, it is relevant to better understand the dietary aspects related to the acid-base balance in chronic kidney disease metabolic acidosis and try to provide possible strategies for the nutritional management of these cases...
December 5, 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/29219869/comparison-of-vegetarian-versus-animal-based-low-protein-diets-on-estimated-glomerular-filtration-rates-in-chronic-kidney-disease-patients-a-systematic-review-protocol
#20
Kruti Patel, Kim W Hoover
The objective of this review is to evaluate studies to determine the effect of a low-protein, vegetarian diet as compared to a low-protein, animal-based diet on estimated glomerular filtration rates (eGFR) in adults with chronic kidney disease (CKD).
December 2017: JBI Database of Systematic Reviews and Implementation Reports
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