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Community paediatrics

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https://www.readbyqxmd.com/read/29665952/community-engagement-for-paediatric-mdr-tb-clinical-trials-principles-to-support-ethical-trial-implementation
#1
G Hoddinott, S Staples, R Brown, M Simwinga, C Mubekapi-Musadaidzwa, A C Hesseling, G Hendricks, P De Koker, L McKenna
The paediatric tuberculosis (TB) prevention and treatment landscape is moving into a new and exciting era, with knowledge from clinical trials offering real benefit to children. Community engagement is key to optimising the success of these trials. However, the clinical profile, epidemiology and social perceptions for paediatric multidrug-resistant TB (MDR-TB) complicate the operationalisation of this community engagement. We reflect on a diversity of recent experiences attempting to implement this type of research and the community engagement around it...
May 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29659884/results-from-the-survey-of-antibiotic-resistance-soar-2014-16-in-greece
#2
D Torumkuney, J Papaparaskevas, I Morrissey
Objectives: To determine antimicrobial susceptibility in isolates of Streptococcus pneumoniae and Haemophilus influenzae collected in 2014-16 from patients with community-acquired respiratory tract infections in Greece. Methods: MICs were determined by CLSI broth microdilution and susceptibility assessed using CLSI, EUCAST and pharmacokinetic/pharmacodynamic (PK/PD) breakpoints. Results: A total of 99 S. pneumoniae and 52 H. influenzae isolates were collected...
April 1, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29656273/the-feasibility-and-concurrent-validity-of-performing-the-movement-assessment-battery-for-children-2nd-edition-via-telerehabilitation-technology
#3
Kristy Nicola, Jemimah Waugh, Emily Charles, Trevor Russell
BACKGROUND: In rural and remote communities children with motor difficulties have less access to rehabilitation services. Telerehabilitation technology is a potential method to overcome barriers restricting access to healthcare in these areas. Assessment is necessary to guide clinical reasoning; however it is unclear which paediatric assessments can be administered remotely. The Movement Assessment Battery for Children - 2nd Edition is commonly used by various health professionals to assess motor performance of children...
April 12, 2018: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29629679/feasibility-and-acceptability-of-conducting-hiv-vaccine-trials-in-adolescents-in-south-africa-going-beyond-willingness-to-participate-towards-implementation
#4
M Wallace, K Middelkoop, P Smith, C Pike, T Bennie, J Chandia, G Churchyard, G Gray, M H Latka, M Mathebula, M Nchabeleng, S Roux, C Slack, A Strode, L-G Bekker
BACKGROUND: HIV/AIDS remains a leading cause of death in adolescents (aged 15 - 25 years), and in sub-Saharan Africa HIV-related deaths continue to rise in this age group despite a decline in both adult and paediatric populations. This is attributable in part to high adolescent infection rates and supports the urgent need for more efficacious prevention strategies. In particular, an even partially effective HIV vaccine, given prior to sexual debut, is predicted to significantly curb adolescent infection rates...
March 28, 2018: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29621601/results-from-the-third-scottish-national-prevalence-survey-is-a-population-health-approach-now-needed-to-prevent-hai
#5
Shona Cairns, Cheryl Gibbons, Aynsley Milne, Hazel King, Melissa Llano, Laura MacDonald, William Malcolm, Chris Robertson, Jacqueline Sneddon, Jennifer Weir, Jacqui Reilly
BACKGROUND: Healthcare associated infections (HAI) are a major public health concern and a significant cause of morbidity and mortality. A robust and current evidence base that is specific to local, national and Europe-wide settings is necessary to inform the development of strategies to reduce HAI and contain antimicrobial resistance (AMR). AIM: To measure the prevalence of HAI and antimicrobial prescribing and identify key priority areas for interventions to reduce the burden of infection...
April 2, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29618484/evaluating-the-process-and-outcomes-of-child-death-review-in-the-solomon-islands
#6
Mathew Sandakabatu, Titus Nasi, Carol Titiulu, Trevor Duke
While maternal and perinatal mortality auditing has been strongly promoted by the World Health Organization (WHO), there has been very limited promotion or evaluation of child death auditing in low/middle-income settings. In 2017, a standardised child death review process was introduced in the paediatric department of the National Hospital in Honiara, Solomon Islands. We evaluated the process and outcomes of child death reviews. The child death auditing process was assessed through systematic observations made at each of the weekly meetings using the following standards for evaluation: (1) adapted WHO tools for paediatric auditing; (2) the five stages of the audit cycle; (3) published principles of paediatric audit; and (4) WHO and Solomon Islands national clinical standards of Hospital Care for Children...
April 4, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29618237/transition-from-paediatric-to-adult-healthcare-for-young-people-with-cystic-fibrosis-parents-information-needs
#7
Imelda Coyne, Helen Malone, Emma Chubb, Alison E While
Parents of young people with cystic fibrosis (YPWCF) play an important role during the transition from paediatric to adult health services. There is limited evidence on parental information needs and the extent to which they are met. An online survey was conducted targeting a finite population of 190 parents of YPWCF in Ireland. Fifty-nine parents responded (31% response rate). Parents reported the need for more general preparation and timing of the transfer, more information regarding the differences between adult and child health services and how their child will self-manage his/her illness in the future...
January 1, 2018: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29610937/paediatric-musculoskeletal-disease-in-kumi-district-uganda-a-cross-sectional-survey
#8
Kristin Alves, Norgrove Penny, Olive Kobusingye, Robert Olupot, Jeffrey N Katz, Coleen S Sabatini
PURPOSE: The purpose of this study is to estimate the burden of musculoskeletal disease among children treated in Kumi District, Uganda, to inform training, capacity-building efforts, and resource allocation. METHODS: We conducted a retrospective cohort study by reviewing the musculoskeletal (MSK) clinic and community outreach logs for children (age < 18 years) seen at Kumi Hospital in Kumi, Uganda, between January 2013 and December 2015. For each patient, we recorded the age, sex, diagnosis, and treatment recommendation...
April 2, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29601554/treatment-options-for-paediatric-anaplastic-large-cell-lymphoma-alcl-current-standard-and-beyond
#9
REVIEW
Nina Prokoph, Hugo Larose, Megan S Lim, G A Amos Burke, Suzanne D Turner
Anaplastic Lymphoma Kinase (ALK)-positive Anaplastic Large Cell Lymphoma (ALCL), remains one of the most curable cancers in the paediatric setting; multi-agent chemotherapy cures approximately 65-90% of patients. Over the last two decades, major efforts have focused on improving the survival rate by intensification of combination chemotherapy regimens and employing stem cell transplantation for chemotherapy-resistant patients. More recently, several new and 'renewed' agents have offered the opportunity for a change in the paradigm for the management of both chemo-sensitive and chemo-resistant forms of ALCL...
March 30, 2018: Cancers
https://www.readbyqxmd.com/read/29596188/chapter-7-the-contributions-of-the-espghan-committees-on-nutrition-to-paediatric-nutrition
#10
Olle Hernell, Peter Aggett, Mary Fewtrell, Berthold Koletzko, Jean Rey
The first Committee on Nutrition (CoN) was founded in 1974. Two years later nutrition (N) was added to the society's name, which then became ESPGAN. The Committee systematised compositional and quality criteria for breast milk substitutes and food for special medical purposes, the first of many examples on how recommendations and comments published by the Committees on Nutrition (CsoN) were adopted by the European Economic Community, later the European Union and also influenced the World Health Organization/Food and Agriculture Organization of the United Nations Codex standards...
April 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29579186/arrhythmias-in-congenital-heart-disease-a-position-paper-of-the-european-heart-rhythm-association-ehra-association-for-european-paediatric-and-congenital-cardiology-aepc-and-the-european-society-of-cardiology-esc-working-group-on-grown-up-congenital-heart-disease
#11
Antonio Hernández-Madrid, Thomas Paul, Dominic Abrams, Peter F Aziz, Nico A Blom, Jian Chen, Massimo Chessa, Nicolas Combes, Nikolaos Dagres, Gerhard Diller, Sabine Ernst, Alessandro Giamberti, Joachim Hebe, Jan Janousek, Thomas Kriebel, Jose Moltedo, Javier Moreno, Rafael Peinado, Laurent Pison, Eric Rosenthal, Jonathan R Skinner, Katja Zeppenfeld
The population of patients with congenital heart disease (CHD) is continuously increasing with more and more patients reaching adulthood. A significant portion of these young adults will suffer from arrhythmias due to the underlying congenital heart defect itself or as a sequela of interventional or surgical treatment. The medical community will encounter an increasing challenge as even most of the individuals with complex congenital heart defects nowadays become young adults. Within the past 20 years, management of patients with arrhythmias has gained remarkable progress including pharmacological treatment, catheter ablation, and device therapy...
March 20, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29570494/the-impact-of-paediatric-antimicrobial-stewardship-programmes-on-patient-outcomes
#12
Sanjay V Patel, Stefania Vergnano
PURPOSE OF REVIEW: Although there has been an unprecedented global effort to reduce the spread of antimicrobial resistance, little emphasis has been placed on children. This review aims to evaluate the impact of paediatric antimicrobial stewardship programmes as well as providing a practical approach for effectively implementing them in community-based settings and in hospitals. RECENT FINDINGS: Although rates of serious bacterial infection are low in children, the rates of antimicrobial use and resistance are comparable with adults...
March 22, 2018: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/29552921/a-randomized-controlled-trial-to-compare-two-methods-of-constraint-induced-movement-therapy-to-improve-functional-ability-in-the-affected-upper-limb-in-pre-school-children-with-hemiplegic-cerebral-palsy-catch-trial
#13
Pauline M Christmas, Catherine Sackley, Max G Feltham, Carole Cummins
OBJECTIVE: To determine the feasibility and short-term efficacy of caregiver-directed constraint-induced movement therapy to improve upper limb function in young children with hemiplegic cerebral palsy. DESIGN: Randomized controlled trial with masked assessment. SETTING: Community paediatric therapy services. SUBJECTS: Pre-school children with hemiplegic cerebral palsy. INTERVENTIONS: Caregiver-directed constraint-induced movement therapy administered using either 24-hour short-arm restraint device (prolonged) or intermittent holding restraint during therapy (manual)...
March 1, 2018: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29541438/practice-patterns-and-determinants-of-wait-time-for-autism-spectrum-disorder-diagnosis-in-canada
#14
Melanie Penner, Evdokia Anagnostou, Wendy J Ungar
Background: Inefficient diagnostic practices for autism spectrum disorder (ASD) may contribute to longer wait times, delaying access to intervention. The objectives were to describe the diagnostic practices of Canadian pediatricians and to identify determinants of longer wait time for ASD diagnosis. Methods: An online survey was conducted through the Canadian Paediatric Society's developmental pediatrics, community pediatrics, and mental health sections. Participants were asked for demographic information, whether they diagnosed ASD, and elements of their diagnostic assessment...
2018: Molecular Autism
https://www.readbyqxmd.com/read/29491724/tobacco-use-and-misuse-among-indigenous-children-and-youth-in-canada
#15
Radha Jetty
While tobacco is sacred in many Indigenous cultures, the recreational misuse of commercial tobacco is highly addictive and harmful. Tobacco misuse is the leading preventable cause of premature death in the world. Smoking rates among Canadian Indigenous youth are at least three times higher than for their non-Aboriginal peers, an alarming statistic on many levels. The tolls on health from extensive tobacco use range from disproportionately high individual mortality and morbidity to heavy socioeconomic burdens on Indigenous communities...
October 2017: Paediatrics & Child Health
https://www.readbyqxmd.com/read/29491035/paediatric-lung-imaging-the-times-they-are-a-changin
#16
REVIEW
Harm A W M Tiddens, Wieying Kuo, Marcel van Straten, Pierluigi Ciet
Until recently, functional tests were the most important tools for the diagnosis and monitoring of lung diseases in the paediatric population. Chest imaging has gained considerable importance for paediatric pulmonology as a diagnostic and monitoring tool to evaluate lung structure over the past decade. Since January 2016, a large number of papers have been published on innovations in chest computed tomography (CT) and/or magnetic resonance imaging (MRI) technology, acquisition techniques, image analysis strategies and their application in different disease areas...
March 31, 2018: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/29490519/cost-and-outcome-of-a-community-based-paediatric-hearing-screening-programme-in-rural-india-with-application-of-tele-audiology-for-follow-up-diagnostic-hearing-assessment
#17
Vidya Ramkumar, K R John, K Selvakumar, C S Vanaja, Roopa Nagarajan, James W Hall
OBJECTIVE: This study evaluated the cost and outcome of a community-based hearing screening programme in which village health workers (VHWs) screened children in their homes using a two-step DPOAE screening protocol. Children referred in a second screening underwent tele diagnostic ABR testing in a mobile tele-van using satellite connectivity or at local centre using broadband internet at the rural location. DESIGN: Economic analysis was carried out to estimate cost incurred and outcome achieved for hearing screening, follow-up diagnostic assessment and identification of hearing loss...
February 28, 2018: International Journal of Audiology
https://www.readbyqxmd.com/read/29485739/sustainable-survival-for-adolescents-living-with-hiv-do-sdg-aligned-provisions-reduce-potential-mortality-risk
#18
Lucie Cluver, Marija Pantelic, Mark Orkin, Elona Toska, Sally Medley, Lorraine Sherr
INTRODUCTION: The Sustainable Development Goals (SDGs) present a groundbreaking global development agenda to protect the most vulnerable. Adolescents living with HIV in Sub-Saharan Africa continue to experience extreme health vulnerabilities, but we know little about the impacts of SDG-aligned provisions on their health. This study tests associations of provisions aligned with five SDGs with potential mortality risks. METHODS: Clinical and interview data were gathered from N = 1060 adolescents living with HIV in rural and urban South Africa in 2014 to 2015...
February 2018: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29479861/where-have-all-the-children-gone-high-hiv-prevalence-in-infants-attending-nutrition-and-inpatient-entry-points
#19
Charles Kiyaga, Brittany Urick, Youyi Fong, Christopher Okiira, Nicolette Nabukeera-Barungi, Denis Nansera, Emmanuel Ochola, Julius Nteziyaremye, Victor Bigira, Isaac Ssewanyana, Peter Olupot-Olupot, Trevor Peter, Anisa Ghadrshenas, Lara Vojnov
INTRODUCTION: Despite notable progress towards PMTCT, only 50% of HIV-exposed infants in sub-Saharan Africa were tested within the first 2 months of life and only 30% of HIV-infected infants are on antiretroviral treatment. This study assessed HIV prevalence in infants and children receiving care at various service entry points in primary healthcare facilities in Uganda. METHODS: A total of 3600 infants up to 24 months of age were systematically enrolled and tested at four regional hospitals across Uganda...
February 2018: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29479197/prevalence-and-predictors-of-low-serum-25-hydroxyvitamin-d-levels-in-rural-canadian-children
#20
Michelle Science, Jonathon L Maguire, Margaret L Russell, Marek Smieja, Stephen D Walter, Mark Loeb
Objectives: Studies in Canada have reported varying prevalences of low serum 25-hydroxyvitamin D (25(OH)D) levels, but none have been conducted in rural paediatric populations. The purpose of this study was to determine the prevalence and predictors of low vitamin D levels in rural communities. Methods: We conducted a cross-sectional study of children aged 3 to 15 living in Canadian Hutterite communities. Serum 25(OH)D levels were measured between October 2008 and April 2009 using a chemiluminescence assay...
June 2017: Paediatrics & Child Health
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