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https://www.readbyqxmd.com/read/29232913/pharmacoeconomic-analysis-of-drugs-used-in-the-treatment-of-pneumonia-in-paediatric-population-in-a-tertiary-care-hospital-in-india-a-cost-of-illness-study
#1
Lekha Saha, Sharonjeet Kaur, Pratibha Khosla, Sweta Kumari, Alka Rani
AIMS AND OBJECTIVES: The cost of antibiotic therapy for the treatment of pneumonia in the inpatient paediatric population can have a major impact on the healthcare expenditure. We planned to assess the direct and indirect costs of diagnosis and medical treatment of paediatric patients with community acquired pneumonia who are hospitalized in a tertiary care hospital in India. METHODS: 125 children with a diagnosis of pneumonia who were admitted to the inpatient department of a paediatric hospital receiving antibiotic treatment were observed...
December 11, 2017: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/29228220/the-burden-of-presumed-tuberculosis-in-hospitalized-children-in-a-resource-limited-setting-in-papua-new-guinea-a-prospective-observational-study
#2
Villa Watch, Jimmy Aipit, Tina Kote-Yarong, Allanie Rero, John W Bolnga, Elvin Lufele, Moses Laman
Background: In Papua New Guinea, TB is considered to be a major public health problem, but little is known about the prevalence and prognosis of presumed TB in children. Methods: As part of a prospective hospital-based surveillance on the northern coast of mainland Papua New Guinea, the authors investigated the admission prevalence and case fatality rate associated with presumed TB over a 6-year period (2011-2016). All children admitted who were diagnosed with TB were followed-up until discharge or death...
December 8, 2017: International Health
https://www.readbyqxmd.com/read/29223147/the-unmet-provision-of-allergy-services-in-hong-kong-impairs-capability-for-allergy-prevention-implications-for-the-asia-pacific-region
#3
Tak-Hong Lee, Ting-Fan Leung, Gary Wong, Marco Ho, Jaime Rosa Duque, Philip Hei Li, Chak-Sing Lau, Wai-Fan Lam, Adrian Wu, Eric Chan, Christopher Lai, Yu-Lung Lau
There is a high and rising prevalence of many allergic diseases in the Asia Pacific, including Hong Kong, which is unmatched by a commensurate provision of clinical allergy services. In the last 3 years, the allergy profile in Hong Kong has increased due to greater public engagement and more frequent educational activities, scientific outputs and publication of local guidelines on allergy prevention, diagnosis and treatment. Two new drug allergy clinics have been established in public hospitals, and for the first time in 20 years, Hong Kong has its first trainee in adult allergy...
December 10, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/29217093/risk-factors-for-the-appearance-of-secondary-foci-of-infection-in-children-with-community-acquired-staphylococcus-aureus-bacteraemia-cohort-study-2010-2016
#4
M Guadalupe Perez, Soledad Martiren, Florencia Escarra, Vanesa Reijtman, Alejandra Mastroianni, Ana Varela-Baino, Carola Cedillo, M Eva Garcia, Moira Taicz, Rosa Bologna
INTRODUCTION: Community-acquired Staphylococcus aureus (SA) bacteraemia is a common cause of hospitalisation in children. The occurrence of secondary foci (SF) of SA infection is associated with higher morbidity and mortality. OBJECTIVES: To identify risk factors for SF of infection in children with community-acquired SA bacteraemia. MATERIAL AND METHODS: Prospective cohort. All children aged from 30 days to 16 years admitted to a paediatric referral hospital between January 2010 and December 2016 for community-acquired infections, with SA isolated in blood cultures, were included...
December 4, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29210182/topical-ofloxacin-use-in-g6pd-deficiency-safe-or-unsafe
#5
Natalie Watson, Manuel Gomez Serrano, David Selvadurai
we have recently treated a paediatric patient with known glucose-6-phosphate dehydrogenase (G6PD) deficiency and wished to communicate to the clinical ENT community the controversies around the use of fluoroquinolone (FQ) antibiotic drops in this patient cohort. This article is protected by copyright. All rights reserved.
December 6, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29207958/bloodstream-infections-at-a-tertiary-level-paediatric-hospital-in-south-africa
#6
Harsha Lochan, Vashini Pillay, Colleen Bamford, James Nuttall, Brian Eley
BACKGROUND: Bloodstream infection (BSI) in children causes significant morbidity and mortality. There are few studies describing the epidemiology of BSI in South African children. METHODS: A retrospective descriptive cohort study was conducted at a paediatric referral hospital in Cape Town, South Africa. The National Health Laboratory Service (NHLS) microbiology database was accessed to identify positive blood culture specimens during the period 2011-2012. Demographic and clinical details, antimicrobial management and patient outcome information were extracted from medical and laboratory records...
December 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29204852/european-antibiotic-awareness-day-2017-training-the-next-generation-of-health-care-professionals-in-antibiotic-stewardship
#7
Lenneke Schrier, Adamos Hadjipanayis, Stefano Del Torso, Tom Stiris, Marieke Emonts, Hans Juergen Dornbusch
Antimicrobial stewardship (AMS) aims to optimise treatment, minimise the risk of adverse effects and reduce health care costs. In addition, it is recognised as a key component to stop the current spread of antimicrobial resistance in Europe. Educational programmes are particularly important for the successful implementation of AMS. Training should start during medical school, continue during clinical training and be reinforced throughout postgraduate training. National core curricula for paediatric training should include passive and active training of competencies needed for AMS and future paediatricians should be skilled in taking leadership roles in AMS initiatives...
December 5, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29201146/time-to-revise-our-dialogue-how-flat-is-the-paediatric-flatfoot
#8
Stewart C Morrison, Juliet McClymont, Carina Price, Chris Nester
A recent systematic review of measures of foot development used the medial longitudinal arch profile as its primary indicator of development. A comparative analysis of existing studies was undertaken. This work confirmed changes with arch profile were age-dependent, although the age at which foot development ceased remains unknown. This work also highlighted the abundance of clinical measures used in existing research and outlined the challenges with drawing consensus from available data. There is a clear need to move this debate forward and, to do so, it is essential that scientific and clinical communities unite...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29170350/53%C3%A2-piloting-patch-providing-assessment-and-treatment-for-children-at-home-and-piecing-together-what-works
#9
Caroline Ward, Katie Knight, Mary-Rose Ballard, Georgina Keogh, Miriam Samuel, Sara Buttle, Claire Robb, Francesca Cleugh
AIMS: PATCH is a pilot acute community children's nurse led service delivering assessment and treatment for children at home who are moderately unwell and might otherwise be admitted to hospital or attend Paediatric Emergency Department (PED). Children are referred by PED or GP and followed up via telephone support and home visits depending on clinical need for duration of acute illness. METHODS: Pilot year funded by Imperial Charity. Using evaluation to build business case for sustained commissioned service...
December 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29168910/parental-immunisation-needs-and-attitudes-survey-in-paediatric-hospital-clinics-and-community-maternal-and-child-health-centres-in-melbourne-australia
#10
Jessica C Costa-Pinto, Harold W Willaby, Julie Leask, Monsurul Hoq, Tibor Schuster, Alice Ghazarian, Jacinta O'Keefe, Margie H Danchin
AIM: Despite Australia's high vaccination rates, an estimated 3.3% of children are under-vaccinated due to vaccine refusal and the proportion of parents with concerns is unclear. Amongst Australian parents, we aimed to determine the prevalence of vaccine concerns, resources and health-care providers (HCPs) accessed and satisfaction with these resources in two different settings. We also aimed to identify relationships between the level of vaccine concern, socio-economic status and vaccine uptake...
November 23, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29152325/changes-of-intestinal-microbiota-composition-and-diversity-in-very-low-birth-weight-infants-related-to-strategies-of-nec-prophylaxis-protocol-for-an-observational-multicentre-pilot-study
#11
Stefan Kurath-Koller, Christine Moissl-Eichinger, Gregor Gorkiewicz, Raimund Kraschl, Claudia Kanduth, Barbara Hopfer, Berndt Urlesberger, Bernhard Resch
Background: At the Division of Neonatology, Department of Paediatrics, Medical University Graz, a unique regimen of necrotizing enterocolitis (NEC) prophylaxis in preterm infants showing a < 1500 g birth weight (i.e. very low birth weight, VLBW) is used. The regimen includes oral antibiotic and antifungal therapy and probiotic preparations as well as a standardised feeding regimen. The incidence of NEC in preterm infants treated by this regimen has been shown to be lower, reflecting 0...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29146655/qualitative-evaluation-of-a-deferred-consent-process-in-paediatric-emergency-research-a-predict-study
#12
Jeremy Furyk, Kristin McBain-Rigg, Kerrianne Watt, Theophilus I Emeto, Richard C Franklin, Donna Franklin, Andreas Schibler, Stuart R Dalziel, Franz E Babl, Catherine Wilson, Natalie Phillips, Robin Ray
BACKGROUND: A challenge of conducting research in critically ill children is that the therapeutic window for the intervention may be too short to seek informed consent prior to enrolment. In specific circumstances, most international ethical guidelines allow for children to be enrolled in research with informed consent obtained later, termed deferred consent (DC) or retrospective consent. There is a paucity of data on the attitudes of parents to this method of enrolment in paediatric emergency research...
November 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29146601/airway-microbiota-across-age-and-disease-spectrum-in-cystic-fibrosis
#13
Edith T Zemanick, Brandie D Wagner, Charles E Robertson, Richard C Ahrens, James F Chmiel, John P Clancy, Ronald L Gibson, William T Harris, Geoffrey Kurland, Theresa A Laguna, Susanna A McColley, Karen McCoy, George Retsch-Bogart, Kurtis T Sobush, Pamela L Zeitlin, Mark J Stevens, Frank J Accurso, Scott D Sagel, J Kirk Harris
Our objectives were to characterise the microbiota in cystic fibrosis (CF) bronchoalveolar lavage fluid (BALF), and determine its relationship to inflammation and disease status.BALF from paediatric and adult CF patients and paediatric disease controls undergoing clinically indicated bronchoscopy was analysed for total bacterial load and for microbiota by 16S rDNA sequencing.We examined 191 BALF samples (146 CF and 45 disease controls) from 13 CF centres. In CF patients aged <2 years, nontraditional taxa (e...
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29144024/epidemiology-of-type-1-diabetes-in-polish-children-a-multicentre-cohort-study
#14
Mieczysław Szalecki, Marta Wysocka-Mincewicz, Anna Ramotowska, Artur Mazur, Lucyna Lisowicz, Iwona Ben-Skowronek, Joanna Sieniawska, Bożena Klonowska, Dorota Charemska, Jolanta Nawrotek, Irena Jałowiec, Artur Bossowski, Milena Jamiołkowska, Beata Pyrżak, Grażyna Miszkurka, Agnieszka Szypowska
BACKGROUND: The incidence of childhood Type-1 diabetes (T1D) varies greatly between populations and the estimates and/or predictions of the rates would aid in adequate planning of health care resources. The study's aim was to assess the incidence of T1D in the paediatric population of eastern and central Poland. METHODS: In this cohort study covering the period from January 2010 to December 2014 data were collected for children and adolescents below 18 years of age with newly diagnosed T1D, living in eastern and central Poland...
November 16, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/29123603/paediatric-appropriate-facilities-in-emergency-departments-of-community-hospitals-in-ontario-a-cross-sectional-study
#15
Muhammad Akhter Hamid, Sohaib Siddiqui, Jabeen Fayyaz, Ayesha Chandna, Aliya Ariz, Joe Butchey, Elancheliyan Ambalavanar, Niraj Mistry, Aftab Muhammad Azad, Junaid A Bhatti, Dennis Scolnik
BACKGROUND: We assessed whether the paediatric-appropriate facilities were available at Emergency Departments (ED) in community hospitals in a Canadian province. METHODS: We conducted a cross-sectional survey of EDs in community hospitals in Ontario, Canada that had inpatient paediatric facilities and a neonatal intensive care unit. Key informants were ED chiefs, clinical educators, or managers. The survey included questions about paediatric facilities related to environment, triage, training, and staff in EDs...
2017: World Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29122906/safety-netting-versus-overtreatment-in-paediatrics-viral-infection-or-incomplete-kawasaki-disease
#16
Jennifer Michelle Charlesworth, Bernadette Power, Edina Moylett
Kawasaki disease (KD) is the most common systemic vasculitis of childhood. The following presentation of a 4-year-old Irish boy referred to a secondary care paediatric service from the community with prolonged fever, oral mucous membrane changes and painless blistering lesions of the hands and feet in the presence of elevated inflammatory markers serves as an opportunity to discuss the diagnostic criteria and treatment for KD and incomplete KD, an often missed diagnosis with significant paediatric morbidity outside an academic paediatric centre...
November 8, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29122828/referrals-to-a-perinatal-specialist-palliative-care-consult-service-in-ireland-2012-2015
#17
Des L McMahon, Marie Twomey, Maeve O'Reilly, Mary Devins
OBJECTIVE: To analyse the referral patterns of perinatal patients referred to a specialist palliative care service (SPCS), their demographics, diagnoses, duration of illness, place of death and symptom profile. DESIGN: A retrospective chart review of all perinatal referrals over a 4-year period to the end of 2015. SETTING: A consultant-led paediatric SPCS at Our Lady's Children's Hospital, Crumlin, Dublin, and the Coombe Women & Infants University Hospital, Dublin...
November 9, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29113911/access-to-care-in-rare-liver-diseases-new-challenges-and-new-opportunities
#18
REVIEW
David Jones, Ekkehard Sturm, Ansgar W Lohse
Patients with rare diseases are often disadvantaged, and this applies to rare liver disease in particular. Reasons for disadvantage include delayed or overlooked diagnosis, lack of local expertise and high quality care, poor scientific understanding of the disease process and limited therapeutic options. In adult liver disease in particular this can be compounded by prejudices towards patients with liver disease in general because of a perception (incorrect for all rare liver disease), that liver disease is lifestyle related and thus "self-inflicted"...
November 4, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/29092651/virtual-community-centre-for-power-wheelchair-training-experience-of-children-and-clinicians
#19
Caryne Torkia, Stephen E Ryan, Denise Reid, Patrick Boissy, Martin Lemay, François Routhier, Resi Contardo, Janet Woodhouse, Phillipe S Archambault
PURPOSE: To: 1) characterize the overall experience in using the McGill immersive wheelchair - community centre (miWe-CC) simulator; and 2) investigate the experience of presence (i.e., sense of being in the virtual rather than in the real, physical environment) while driving a PW in the miWe-CC. METHOD: A qualitative research design with structured interviews was used. Fifteen clinicians and 11 children were interviewed after driving a power wheelchair (PW) in the miWe-CC simulator...
November 2, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29082537/the-internet-as-a-source-of-support-for-youth-with-chronic-conditions-a-qualitative-study
#20
S Ahola Kohut, C LeBlanc, K O'Leary, A C McPherson, E McCarthy, C Nguyen, J Stinson
BACKGROUND: Adolescents living with chronic conditions often portray themselves as "healthy" online, yet use the Internet as one of their top sources of health information and social communication. There is a need to develop online support programs specific to adolescents with chronic conditions in order to provide a private space to discuss concerns. This paper endeavors to increase our understanding of the online support needs and wants of these adolescents and their interest in and preferences for an online support program...
October 29, 2017: Child: Care, Health and Development
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