Muhammad Atif Ameer, Haroon Chaudhry, Javaria Mushtaq, Osama S Khan, Maham Babar, Tehmina Hashim, Saima Zeb, Muhammad Ali Tariq, Sridhar Reddy Patlolla, Junaid Ali, Syeda Nafeesa Hashim, Sana Hashim
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystem involvement. It is multifactorial and involves epigenetic, genetic, ecological, and environmental factors. Primarily it leads to activation of both innate and adaptive immunity, which consequently leads to autoreactive B cell activation by T cells and leads to immune complexes deposition in tissues leading to an autoimmune cascade that may be limited to the single organ or can cause a widespread systemic involvement...
October 2022: Curēus