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https://www.readbyqxmd.com/read/28916995/effects-of-environmental-enrichment-on-self-administration-of-the-short-acting-opioid-remifentanil-in-male-rats
#1
Rebecca S Hofford, Jonathan J Chow, Joshua S Beckmann, Michael T Bardo
BACKGROUND: Opioid abuse is a major problem around the world. Identifying environmental factors that contribute to opioid abuse and addiction is necessary for decreasing this epidemic. In rodents, environmental enrichment protects against the development of low dose stimulant self-administration, but studies examining the effect of enrichment and isolation (compared to standard housing) on the development of intravenous opioid self-administration have not been conducted. The present study investigated the role of environmental enrichment on self-administration of the short-acting μ-opioid remifentanil...
September 15, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28903835/soyabean-oil-supplementation-effects-on-perivascular-inflammation-in-lungs-induced-by-bisphenol-a-a-histological-study
#2
Sadia Shaukat, Shabnam Hamid, Faiza Umbreen
OBJECTIVE: To determine the effect of soyabean oil supplementation on perivascular inflammation in lungs of adult mice induced by Bisphenol A(BPA). STUDY DESIGN: An experimental study. PLACE AND DURATION OF STUDY: Department of Anatomy, Army Medical College, Rawalpindi, in collaboration with the Animal House, National Institute of Health, Islamabad, from June to November 2016. METHODOLOGY: Thirty male and female BALB/c mice were divided into three groups, of 10 animals each...
August 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28893674/seroepidemiology-of-leptospirosis-among-febrile-patients-in-a-rapidly-growing-suburban-slum-and-a-flood-vulnerable-rural-district-in-mozambique-2012-2014-implication-for-the-management-of-fever
#3
Policarpo Ribeiro, Nilesh Bhatt, Sádia Ali, Vanessa Monteiro, Edmilson da Silva, Ilana Teruszkin Balassiano, Carolina Aquino, Nilsa de de Deus, Onelia Guiliche, Argentina Felisbela Muianga, Pascoal Jorge Alho, Virginia Lara Evaristo, Ivan Manhiça, Marco Medeiros, Eduardo Samo Gudo
OBJECTIVE: Leptospirosis, is one of most widespread zoonosis in the world and is caused by spirochetes of the genus Leptospira. In Mozambique, the disease is heavily ignored and its epidemiology is unknown. The objective of this study was to investigate occurrence of leptospirosis in febrile patients. METHODS: A cross-sectional study was conducted among febrile patients between June 2012 and September 2015. A total of 373 paired samples were drawn from febrile patients, of whom 208 were from Caia District Hospital (rural setting) in Sofala province and 165 were from Polana Caniço General Hospital (suburban setting) in Maputo city...
September 8, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28877172/automated-recording-of-home-cage-activity-and-temperature-of-individual-rats-housed-in-social-groups-the-rodent-big-brother-project
#4
William S Redfern, Karen Tse, Claire Grant, Amy Keerie, David J Simpson, John C Pedersen, Victoria Rimmer, Lauren Leslie, Stephanie K Klein, Natasha A Karp, Rowland Sillito, Agis Chartsias, Tim Lukins, James Heward, Catherine Vickers, Kathryn Chapman, J Douglas Armstrong
Measuring the activity and temperature of rats is commonly required in biomedical research. Conventional approaches necessitate single housing, which affects their behavior and wellbeing. We have used a subcutaneous radiofrequency identification (RFID) transponder to measure ambulatory activity and temperature of individual rats when group-housed in conventional, rack-mounted home cages. The transponder location and temperature is detected by a matrix of antennae in a baseplate under the cage. An infrared high-definition camera acquires side-view video of the cage and also enables automated detection of vertical activity...
2017: PloS One
https://www.readbyqxmd.com/read/28872575/partner-loss-in-monogamous-rodents-modulation-of-pain-and-emotional-behavior-in-male-prairie-voles
#5
Yoji Osako, Reiko Nobuhara, Young-Chang P Arai, Kenjiro Tanaka, Larry J Young, Makoto Nishihara, Shinichi Mitsui, Kazunari Yuri
OBJECTIVE: Pain is modulated by psychosocial factors and social stress-induced hyperalgesia is a common clinical symptom in pain disorders. To provide a new animal model for studying social modulation of pain, we examined pain behaviors in monogamous prairie voles experiencing partner loss. METHODS: After cohabitation with novel females, males (n=79) were divided into two groups on the basis of preference test scores. Half of the males of each group were separated from their partner (loss group), while the other half remained paired (paired group)...
September 1, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28870755/high-seroprevalence-of-toxoplasma-gondii-and-probability-of-detecting-tissue-cysts-in-backyard-laying-hens-compared-with-hens-from-large-free-range-farms
#6
G Schares, B Bangoura, F Randau, T Goroll, M Ludewig, P Maksimov, B Matzkeit, M Sens, A Bärwald, F J Conraths, M Opsteegh, J Van der Giessen
Serological assays are commonly used to determine the prevalence of Toxoplasma gondii infection in livestock, but the predictive value of seropositivity with respect to the presence of infective tissue cysts is less clear. The present study aimed at the identification of seropositive and seronegative free-range laying hens from organic and backyard farms, and the relationship with the presence of viable tissue cysts. In addition, potential risk and protective factors on the selected farms were investigated...
September 5, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/28837565/leishmania-infection-and-blood-food-sources-of-phlebotomines-in-an-area-of-brazil-endemic-for-visceral-and-tegumentary-leishmaniasis
#7
Antônia Suely Guimarães-E-Silva, Soraia de Oliveira Silva, Rosa Cristina Ribeiro da Silva, Valéria Cristina Soares Pinheiro, José Manuel Macário Rebêlo, Maria Norma Melo
The aims of the study were to determine the blood feeding preferences of sandflies and to identify species of Leishmania that infected phlebotomines in Caxias, Maranhão, Brazil, an area that is highly endemic for leishmaniasis. Sandflies were captured in light traps located in the peridomiciliary environments of randomly selected houses in urban and rural settings between 1800 and 0600 hours on new moon days between March 2013 and February 2015. DNA extracts from 982 engorged female sandflies were submitted to fragment length polymorphism analysis to identify infecting species of Leishmania, and blood sources were identified for 778 of these specimens...
2017: PloS One
https://www.readbyqxmd.com/read/28835420/evaluating-the-voiding-spot-assay-in-mice-a-simple-method-with-complex-environmental-interactions
#8
Huan Chen, Lanlan Zhang, Warren G Hill, Weiqun Yu
The voiding spot assay (VSA) on filter paper is an increasingly popular method for studying lower urinary tract physiology in mice. However, the ways VSA are performed differ significantly between laboratories, and many variables are introduced compared to the mouse's normal housing situation. Rodents are intelligent social animals, and it is increasingly understood that social and environmental stresses have significant effects on their physiology. Surprisingly, little is known about whether change of environment during VSA affects mouse voiding, and what the best methodologies are for retaining 'natural' micturition patterns...
August 23, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28827792/characterization-of-monkeypox-virus-infection-in-african-rope-squirrels-funisciurus-sp
#9
Elizabeth A Falendysz, Juan G Lopera, Jeffrey B Doty, Yoshinori Nakazawa, Colleen Crill, Faye Lorenzsonn, Lem's N Kalemba, Monica D Ronderos, Andres Mejia, Jean M Malekani, Kevin Karem, Darin S Carroll, Jorge E Osorio, Tonie E Rocke
Monkeypox (MPX) is a zoonotic disease endemic in Central and West Africa and is caused by Monkeypox virus (MPXV), the most virulent Orthopoxvirus affecting humans since the eradication of Variola virus (VARV). Many aspects of the MPXV transmission cycle, including the natural host of the virus, remain unknown. African rope squirrels (Funisciurus spp.) are considered potential reservoirs of MPXV, as serosurveillance data in Central Africa has confirmed the circulation of the virus in these rodent species [1,2]...
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28806497/tooth-morphogenesis-and-fgf4-expression-during-development-of-molar-tooth-in-three-muroid-rodents-calomyscus-elburzensis-calomyscidae-mesocricetus-auratus-cricetidae-and-mus-musculus-muridae
#10
Kordiyeh Hamidi, Jamshid Darvish, Maryam M Matin, Athar Sadat Javanmard, C William Kilpatrick
To date, no studies have examined the tooth formation during developmental stages of brush-tailed mice (Calomyscidae) and true hamsters (Cricetidae). Herein, we compared the timing of tooth morphogenesis and FGF4 expression pattern during development of the first lower molar in Goodwin's brush-tailed mouse, Calomyscus elburzensis with two other muroid rodents; the house mouse, Mus musculus (Muridae), model organism for tooth morphogenesis, and the golden hamster, Mesocricetus auratus which shares great similarities in cusp pattern with brush-tailed mice...
August 14, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28805432/strain-dependent-sex-differences-in-a-long-term-forced-swim-paradigm
#11
José Colom-Lapetina, Sabrina L Begley, Megan E Johnson, Kristina J Bean, Whitney N Kuwamoto, Rebecca M Shansky
Women are twice as likely as men to suffer from trauma- and stressor-related disorders. The development of improved therapeutic interventions is contingent upon a more complete grasp of both the neural and behavioral dynamics of the stress response in females. The rodent forced swim test (FST) is a valuable animal model for exploring the neurobiological mechanisms responsible for selection of active and passive responses to inescapable stressors, but it is often neglected in 2-day FST studies is the dissociation of innate (Day 1) versus learned (Day 2) coping responses...
August 14, 2017: Behavioral Neuroscience
https://www.readbyqxmd.com/read/28800756/lawsonia-intracellularis-in-the-feces-of-wild-rodents-and-stray-cats-captured-around-equine-farms
#12
Jeong-Min Hwang, Myung-Ji Seo, Jung-Yong Yeh
BACKGROUND: Proliferative enteropathy is a global enteric disease of particular importance in pigs. The causative bacterium, Lawsonia intracellularis, has a wide range of susceptible host species. Recently, L. intracellularis has been recognized as an etiologic agent of an emerging enteric disease in foals called equine proliferative enteropathy (EPE). The presence of L. intracellularis in nonruminant wildlife has raised questions regarding the role of these species in EPE transmission...
August 11, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28799107/determination-of-selected-neurotoxic-insecticides-in-small-amounts-of-animal-tissue-utilizing-a-newly-constructed-mini-extractor
#13
Marta Seifertová, Eliška Čechová, Marta Llansola, Vicente Felipo, Martina Vykoukalová, Anton Kočan
We developed a simple analytical method for the simultaneous determination of representatives of various groups of neurotoxic insecticides (carbaryl, chlorpyrifos, cypermethrin, and α-endosulfan and β-endosulfan and their metabolite endosulfan sulfate) in limited amounts of animal tissues containing different amounts of lipids. Selected tissues (rodent fat, liver, and brain) were extracted in a special in-house-designed mini-extractor constructed on the basis of the Soxhlet and Twisselmann extractors. A dried tissue sample placed in a small cartridge was extracted, while the nascent extract was simultaneously filtered through a layer of sodium sulfate...
August 10, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28796503/effect-of-processing-on-the-in-vitro-and-in-vivo-protein-quality-of-yellow-and-green-split-peas-pisum-sativum
#14
Matthew G Nosworthy, Adam J Franczyk, Gerardo Medina, Jason Neufeld, Paulyn Appah, Alphonsus Utioh, Peter Frohlich, James D House
In order to determine the effect of extrusion, baking, and cooking on the protein quality of yellow and green split peas, a rodent bioassay was conducted and compared to an in vitro method of protein quality determination. The Protein Digestibility-Corrected Amino Acid Score (PDCAAS) of green split peas (71.4%) was higher than that of yellow split peas (67.8%), on average. Similarly, the average Digestible Indispensable Amino Acid Score (DIAAS) of green split peas (69%) was higher than that of yellow split peas (67%)...
September 6, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28783751/animal-related-factors-associated-with-moderate-to-severe-diarrhea-in-children-younger-than-five-years-in-western-kenya-a-matched-case-control-study
#15
MULTICENTER STUDY
Anne Conan, Ciara E O'Reilly, Eric Ogola, J Benjamin Ochieng, Anna J Blackstock, Richard Omore, Linus Ochieng, Fenny Moke, Michele B Parsons, Lihua Xiao, Dawn Roellig, Tamer H Farag, James P Nataro, Karen L Kotloff, Myron M Levine, Eric D Mintz, Robert F Breiman, Sarah Cleaveland, Darryn L Knobel
BACKGROUND: Diarrheal disease remains among the leading causes of global mortality in children younger than 5 years. Exposure to domestic animals may be a risk factor for diarrheal disease. The objectives of this study were to identify animal-related exposures associated with cases of moderate-to-severe diarrhea (MSD) in children in rural western Kenya, and to identify the major zoonotic enteric pathogens present in domestic animals residing in the homesteads of case and control children...
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28758690/rearing-environment-dependent-hippocampal-local-field-potential-differences-in-wild-type-and-inositol-trisphosphate-receptor-type-2-knockout-mice
#16
Mika Tanaka, Xiaowen Wang, Katsuhiko Mikoshiba, Hajime Hirase, Yoshiaki Shinohara
KEY POINTS: Mice reared in an enriched environment are demonstrated to have larger hippocampal gamma oscillations than those reared in isolation, thereby confirming previous observations in rats. To test whether astrocytic Ca(2+) surges are involved in this experience-dependent LFP pattern modulation, we used inositol trisphosphate receptor type 2 (IP3 R2)-knockout (KO) mice, in which IP3 /Ca(2+) signalling in astrocytes is largely diminished. We found that this experience-dependent gamma power alteration persists in the KO mice...
July 31, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28748078/determination-of-the-protein-quality-of-cooked-canadian-pulses
#17
Matthew G Nosworthy, Jason Neufeld, Peter Frohlich, Gina Young, Linda Malcolmson, James D House
A study to determine the protein digestibility-corrected amino acid score and protein efficiency ratio of nine different cooked Canadian pulse classes was conducted in support of the establishment of protein quality claims in Canada and the United States. Split green and yellow pea, whole green lentil, split red lentil, Kabuli chickpea, navy bean, pinto bean, light red kidney bean, and black bean were investigated. Protein digestibility-corrected amino acid score (PDCAAS) and the protein efficiency ratio (PER) were determined using the appropriate rodent models...
July 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28727808/automatic-mouse-ultrasound-detector-a-mud-a-new-tool-for-processing-rodent-vocalizations
#18
Sarah M Zala, Doris Reitschmidt, Anton Noll, Peter Balazs, Dustin J Penn
House mice (Mus musculus) emit complex ultrasonic vocalizations (USVs) during social and sexual interactions, which have features similar to bird song (i.e., they are composed of several different types of syllables, uttered in succession over time to form a pattern of sequences). Manually processing complex vocalization data is time-consuming and potentially subjective, and therefore, we developed an algorithm that automatically detects mouse ultrasonic vocalizations (Automatic Mouse Ultrasound Detector or A-MUD)...
2017: PloS One
https://www.readbyqxmd.com/read/28720383/preliminary-behavioral-assessment-of-cagemates-living-with-conspecifics-submitted-to-chronic-restraint-stress-in-mice
#19
P E Carneiro de Oliveira, Caroline R Zaniboni, Isabela M Carmona, Aura R Fonseca, Azair Canto-de-Souza
The capacity of rodents to recognize and respond to emotional signs from a conspecific is a valuable adaptive behavior, which provides essential skills for species survival. However, repeated exposure to aversive situations may elicit maladaptive behavioral responses in subjects that experience noxious episodes and their colony members. Previous findings by our group demonstrated that living with a subject in neuropathic pain induces anxiogenic-like behaviors and hypernociception in mice. Whereas chronic pain may be considered a stressful stimulus, we extended our findings on stress-induced emotional transfer...
July 15, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28719007/validating-activity-indices-from-camera-traps-for-commensal-rodents-and-other-wildlife-in-and-around-farm-buildings
#20
Mark Lambert, Fiona Bellamy, Richard Budgey, Rebecca Callaby, Julia Coats, Janet Talling
BACKGROUND: Indices of rodent activity are used as indicators of population change during field evaluation of rodenticides. We investigated the potential for using camera traps to determine activity indices for commensal rodents living in and around farm buildings, and sought to compare these indices against previously calibrated survey methods. RESULTS: We recorded 41, 263 images of 23 species including Norway rats (Rattus norvegicus Berk.) and house mice (Mus musculus L...
July 18, 2017: Pest Management Science
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