Robin Capomaccio, Inês Osório, Isaac Ojea-Jiménez, Giacomo Ceccone, Pascal Colpo, Douglas Gilliland, Rohanah Hussain, Giuliano Siligardi, Francois Rossi, Sylvie Ricard-Blum, Luigi Calzolai
Ultraviolet (UV) radiation, temperature, and time can degrade proteins. Here, the authors show that gold nanoparticles significantly protect human serum albumin from denaturation when exposed to "stressing" conditions such as UV irradiation and sustained exposure in suboptimal conditions. In particular, the authors show that gold nanoparticles significantly reduce the decrease in secondary structure induced by UV irradiation or extended exposure to ambient temperature.
December 16, 2016: Biointerphases