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Guillian barre syndrome

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https://www.readbyqxmd.com/read/29091318/early-electrophysiological-findings-in-acute-inflammatory-demyelinating-polyradiculoneuropathy-variant-of-guillain-barre-syndrome-in-the-pakistani-population%C3%A2-%C3%A2-a-comparison-with-global-data
#1
REVIEW
Ahmad Wali, Dureshahwar Kanwar, Safoora A Khan, Sara Khan
Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) and acute motor axonal neuropathy are the most common variants of Guillian-Barre syndrome documented in the Asian population. However, the variability of early neurophysiologic findings in the Asian population compared to western data has not been documented. Eighty-seven cases of AIDP were retrospectively reviewed for their demographic, clinical, electrophysiological, and laboratory data. Mean age of subjects was 31 ± 8 years with males more commonly affected...
November 1, 2017: Journal of the Peripheral Nervous System: JPNS
https://www.readbyqxmd.com/read/28899886/brainstem-encephalitis-and-acute-polyneuropathy-associated-with-hepatitis-e-infection
#2
Omar Jabbar Salim, Amy Davidson, Kathy Li, John Paul Leach, Craig Heath
A 59-year-old man presented with feverish illness. His Glasgow Coma Scale was 15, had reduced visual acuity in the left eye with partial left ptosis and mild left hemiparesis with an extensor left plantar. Over 48 hours, he accrued multiple cranial nerves palsies and progressed to a flaccid paralysis necessitating admission to an intensive care unit.Cerebrospinal fluid (CSF) study showed 20 lymphocytes and raised protein. Viral and bacterial PCRs were negative. Samples for Lyme, blood-borne viruses, syphilis and autoantibodies were also negative...
September 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28879878/guillian-barre-syndrome-and-variants-antiganglioside-antibodies
#3
J M K Murthy
No abstract text is available yet for this article.
September 2017: Neurology India
https://www.readbyqxmd.com/read/28669620/prenatal-tdap-immunization-and-risk-of-maternal-and-newborn-adverse-events
#4
J Bradley Layton, Anne M Butler, Dongmei Li, Kim A Boggess, David J Weber, Leah J McGrath, Sylvia Becker-Dreps
Many countries recommend combined tetanus toxoid, reduced diphtheria toxoid and acellular pertussis immunization (Tdap) during pregnancy to stimulate transplacental transmission of pertussis antibodies to newborns. The immune system can be altered during pregnancy, potentially resulting in differing immunization risks in pregnant women. The safety of widespread Tdap immunization during pregnancy needs to be established. Our objective was to assess whether prenatal Tdap immunization was associated with adverse birth outcomes, and to evaluate the effect of timing of Tdap administration on these outcomes...
July 24, 2017: Vaccine
https://www.readbyqxmd.com/read/28662753/animal-models-of-zika-virus
#5
Michael P Bradley, Claude M Nagamine
Zika virus has garnered great attention over the last several years, as outbreaks of the disease have emerged throughout the Western Hemisphere. Until quite recently Zika virus was considered a fairly benign virus, with limited clinical severity in both people and animals. The size and scope of the outbreak in the Western Hemisphere has allowed for the identification of severe clinical disease that is associated with Zika virus infection, most notably microcephaly among newborns, and an association with Guillian-Barré syndrome in adults...
June 1, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28471623/guillian-barr%C3%A3-syndrome-and-acute-disseminated-encephalomyelitis-related-to-the-bivalent-oral-poliovirus-vaccine
#6
EDITORIAL
Lucija Tomljenovic
No abstract text is available yet for this article.
October 2016: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28457855/polysulfonate-suramin-inhibits-zika-virus-infection
#7
Chee Wah Tan, I-Ching Sam, Wei Lim Chong, Vannajan Sanghiran Lee, Yoke Fun Chan
Zika virus (ZIKV) is an arthropod-borne flavivirus that causes newborn microcephaly and Guillian-Barré syndrome in adults. No therapeutics are available to treat ZIKV infection or other flaviviruses. In this study, we explored the inhibitory effect of glycosaminoglycans and analogues against ZIKV infection. Highly sulfated heparin, dextran sulfate and suramin significantly inhibited ZIKV infection in Vero cells. De-sulfated heparin analogues lose inhibitory effect, implying that sulfonate groups are critical for viral inhibition...
April 27, 2017: Antiviral Research
https://www.readbyqxmd.com/read/28300075/a-human-antibody-against-zika-virus-crosslinks-the-e-protein-to-prevent-infection
#8
S Saif Hasan, Andrew Miller, Gopal Sapparapu, Estefania Fernandez, Thomas Klose, Feng Long, Andrei Fokine, Jason C Porta, Wen Jiang, Michael S Diamond, James E Crowe, Richard J Kuhn, Michael G Rossmann
The recent Zika virus (ZIKV) epidemic has been linked to unusual and severe clinical manifestations including microcephaly in fetuses of infected pregnant women and Guillian-Barré syndrome in adults. Neutralizing antibodies present a possible therapeutic approach to prevent and control ZIKV infection. Here we present a 6.2 Å resolution three-dimensional cryo-electron microscopy (cryoEM) structure of an infectious ZIKV (strain H/PF/2013, French Polynesia) in complex with the Fab fragment of a highly therapeutic and neutralizing human monoclonal antibody, ZIKV-117...
March 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/28273989/healthcare-associated-infections-in-a-resource-limited-setting
#9
Chanaveerappa Bammigatti, Saikumar Doradla, Harish Narasimha Belgode, Harichandra Kumar, Rathinam Palamalai Swaminathan
INTRODUCTION: Health Care associated Infections (HAI) are the most common complications affecting the hospitalized patients. HAI are more common in developing and under developed countries. However, there are no systematic surveillance programs in these countries. AIM: To find out the burden, predisposing factors and multidrug resistant organisms causing HAI in a resource limited setting. MATERIALS AND METHODS: This prospective observational study was done at Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28271821/animal-models-of-zika-virus
#10
Michael P Bradley, Claude M Nagamine
Zika virus has garnered great attention over the last several years, as outbreaks of the disease have emerged throughout the Western Hemisphere. Until quite recently Zika virus was considered a fairly benign virus, with limited clinical severity in both people and animals. The size and scope of the outbreak in the Western Hemisphere has allowed for the identification of severe clinical disease that is associated with Zika virus infection, most notably microcephaly among newborns, and an association with Guillian-Barré syndrome in adults...
March 7, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/27851460/1825-an-atypical-severe-and-rapid-presentation-of-guillian-barr%C3%A3-syndrome
#11
Lyndsay Sprigg, Angella Woodman
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27800000/spontaneous-spinal-epidural-hematoma-coexisting-guillan-barr%C3%A3-syndrome-in-a-child-a-case-report
#12
Chi Hyung Lee, Geun Sung Song, Young Ha Kim, Dong Wuk Son, Sang Weon Lee
Spontaneous spinal epidural hematoma (SSEH) has been reported as a rare cause of spinal cord compression, especially in children. Clinical features are usually nonspecific, although cervicothoracic location of hematoma could be presented with progressive paraplegia. Guillian-Barré syndrome (GBS) is clinically defined as an acute peripheral neuropathy causing progressive limb weakness. Because SSEH and GBS have very similar signs and symptoms, SSEH could be misdiagnosed as GBS. Nevertheless, they can be presented together...
September 2016: Korean Journal of Spine
https://www.readbyqxmd.com/read/27758685/consequence-of-maternal-zika-virus-infection-a-narrative-review
#13
Kamal Niaz, Mohammad Abdollahi
Zika virus (ZIKV) is a deadly flavivirus that has spread from Africa to Asia and European countries. The virus is associated with other viruses in the same genus or family, transmitted by the same mosquito species with known history of fatality. A sudden increase in the rate of infection from ZIKV has made it a global health concern, which necessitates close symptom monitoring, enhancing treatment options, and vaccine production. This paper reviewed current reports on birth defects associated with ZIKV, mode of transmission, body fluids containing the virus, diagnosis , possible preventive measures or treatments, and vaccine development...
October 18, 2016: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/27448322/pain-in-autoimmune-disorders
#14
REVIEW
Katherine A Mifflin, Bradley J Kerr
Most autoimmune diseases are associated with pathological pain development. Autoimmune diseases with pathological pain include complex regional pain syndrome, rheumatoid arthritis, and Guillian-Barré syndrome to name a few. The present Review explores research linking the immune system to the development of pathological pain in autoimmune diseases. Pathological pain has been linked to T-cell activation and the release of cytokines from activated microglia in the dorsal horn of the spinal cord. New research on the role of autoantibodies in autoimmunity has generated insights into potential mechanisms of pain associated with autoimmune disease...
June 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27093288/structure-of-the-thermally-stable-zika-virus
#15
Victor A Kostyuchenko, Elisa X Y Lim, Shuijun Zhang, Guntur Fibriansah, Thiam-Seng Ng, Justin S G Ooi, Jian Shi, Shee-Mei Lok
Zika virus (ZIKV), formerly a neglected pathogen, has recently been associated with microcephaly in fetuses, and with Guillian-Barré syndrome in adults. Here we present the 3.7 Å resolution cryo-electron microscopy structure of ZIKV, and show that the overall architecture of the virus is similar to that of other flaviviruses. Sequence and structural comparisons of the ZIKV envelope (E) protein with other flaviviruses show that parts of the E protein closely resemble the neurovirulent West Nile and Japanese encephalitis viruses, while others are similar to dengue virus (DENV)...
May 19, 2016: Nature
https://www.readbyqxmd.com/read/26853295/guillain-barr%C3%A3-syndrome-after-coronary-artery-bypass-graft-surgery-a-case-report
#16
Manouchehr Hekmat, Hamid Ghaderi, Mahnoosh Foroughi, S Adeleh Mirjafari
Guillain-Barre syndrome is a neurologic disorder that may appear after infection or major surgery. Guillain-Barré syndrome following cardiac surgery is rare and only based on case reports, and we review all of the published cases. A 52-year-old man after 5 months suffering from chest pain was referred to our hospital and underwent coronary artery bypass graft for 3 vessel disease. The patient was discharged without complication on the 5th postoperative day. He presented Guillain-Barré syndrome after 12 months...
January 2016: Acta Medica Iranica
https://www.readbyqxmd.com/read/26721037/acute-flaccid-paralysis-surveillance-a-5-years-study-of-bannu-pakistan
#17
Muhammad Umer Faheem, Muhammad Zeeshan Haroon, Aftab Alam Khan, Maryum Shaukat, Sved Abbas Anwar
BACKGROUND: Acute flaccid paralysis (AFP) is clinical presentation marked by acute onset of weakness and reduced tone. Aetiologies of AFP are diverse including infectious agents, trauma or autoimmune reaction. Currently only three countries in the world that are Nigeria, Pakistan and Afghanistan have endemic poliomyelitis. Pakistan's polio crisis represents one of the last hurdles in a 23-year campaign run by the World Health Organization. Bannu due to its geographical location stands out to be one of highest risk areas for Poliomyelitis...
July 2015: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/26627529/endotracheal-intubation-a-life-saving-procedure-still-potential-hazardous-to-upper-airway-a-case-report
#18
Mahrukh Afreen, Murtaza Ahsan Ansari
Endotracheal intubation plays a key role in the management of upper airway obstruction in emergency situations. It is non-invasive and easily learned technique by medical professionals as compared to other more skilled, surgical procedures, e.g., tracheostomy and cricothyrotomies etc. But prolonged intubation may result in numerous complications, most notorious being tracheoesophageal fistula and narrowing of subglottic area. We report a profile of a patient who had been diagnosed as case of Guillian-Barre Syndrome, had difficulty in breathing due to paralysis of respiratory muscles...
December 2015: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/26409804/guillian-barre-syndrome-as-the-initial-presentation-of-systemic-lupus-erythematosus-case-report-and-review-of-literature
#19
REVIEW
Quaid Nadri, Mohammed Mahdi Althaf
A number of neurological entities have been associated with systemic lupus erythematosus (SLE). Gullian-Barre syndrome (GBS) as a presenting feature of SLE remains uncommon with just 9 cases reported in the last half-century with the first case reported in 19641-9 (Table 1). We report a young female presenting with GBS in whom SLE and WHO class V lupus nephritis (LN) was subsequently diagnosed. The neurological symptoms partially responded to pulse methylprednisone, intravenous immunoglobulin (IVIG) and plasmapheresis...
May 2015: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/26198918/the-frequencies-of-killer-immunoglobulin-like-receptors-and-their-hla-ligands-in-chronic-inflammatory-demyelinating-polyradiculoneuropathy-are-similar-to-those-in-guillian-barre-syndrome-but-differ-from-those-of-controls-suggesting-a-role-for-nk-cells-in-pathogenesis
#20
MULTICENTER STUDY
Stefan Blum, Peter Csurhes, Pamela McCombe
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an acquired inflammatory neuropathy, which has similar clinical and pathological features to Guillain-Barré Syndrome (GBS), but differs in time course. We investigated the frequency of genes encoding Killer immunoglobulin-like receptors and their HLA ligands in subjects with CIDP, in subjects with GBS and in healthy controls. There were no differences in KIR gene frequency among the 3 groups. The gene frequencies for HLA-B Bw4-I were significantly greater in CIDP than HC, but did not differ from GBS...
August 15, 2015: Journal of Neuroimmunology
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