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https://www.readbyqxmd.com/read/29158980/north-atlantic-oscillation-drives-the-annual-occurrence-of-an-isolated-peripheral-population-of-the-brown-seaweed-fucus-guiryi-in-the-western-mediterranean-sea
#1
Ignacio J Melero-Jiménez, A Enrique Salvo, José C Báez, Elena Bañares-España, Andreas Reul, Antonio Flores-Moya
The canopy-forming, intertidal brown (Phaeophyceae) seaweed Fucus guiryi is distributed along the cold-temperate and warm-temperate coasts of Europe and North Africa. Curiously, an isolated population develops at Punta Calaburras (Alboran Sea, Western Mediterranean) but thalli are not present in midsummer every year, unlike the closest (ca. 80 km), perennial populations at the Strait of Gibraltar. The persistence of the alga at Punta Calaburras could be due to the growth of resilient, microscopic stages as well as the arrival of few-celled stages originating from neighbouring localities, and transported by the permanent Atlantic Jet flowing from the Atlantic Ocean into the Mediterranean...
2017: PeerJ
https://www.readbyqxmd.com/read/29151260/the-first-case-of-locked-in-leaflet-after-transcatheter-aortic-valve-replacement-in-a-patient-with-bicuspid-aortic-stenosis
#2
Nao Shibata, Kensuke Matsumoto, Takayoshi Toba, Shumpei Mori, Shinsuke Shimoyama, Hidekazu Tanaka, Toshiro Shinke, Ken-Ichi Hirata
This case report is about an 85-year-old woman with bicuspid aortic stenosis (AS). Although preoperative multimodality imaging showed challenging anatomical aspects, transcatheter aortic valve replacement (TAVR) was selected to be performed as a less invasive alternative treatment approach, owing to her comorbidity. Postoperative transesophageal echocardiography and multidetector-row computed tomography revealed the presence of "locked-in leaflet" caused by stent distortion due to pinching by calcified native leaflets, with nodular calcification preventing the full expansion of the valve, which resulted in moderate perivalvular leakage...
November 19, 2017: Echocardiography
https://www.readbyqxmd.com/read/29146921/plastic-deformation-behaviour-of-single-crystalline-martensite-of-ti-nb-shape-memory-alloy
#3
Masaki Tahara, Nao Okano, Tomonari Inamura, Hideki Hosoda
β-Ti alloys have attracted considerable attention as new biomedical shape memory alloys. Given the critical importance of the plastic deformation in the martensite phase for the shape memory effect and superelasticity, we investigated here the plastic deformation behaviour of a single crystal of α″ (orthorhombic) martensite of Ti-27 mol%Nb shape memory alloy obtained by the stress-induced martensitic transformation of a single crystal of the parent β phase. Four operative plastic deformation modes were observed, including two dislocation slips and two twinnings...
November 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29140949/predictive-ability-and-interobserver-reliability-of-computed-tomography-findings-for-angioembolization-in-patients-with-pelvic-fracture
#4
Shunsuke Yoshikawa, Atsushi Shiraishi, Mitsuhiro Kishino, Makiko Honda, Nao Urushibata, Kosuke Sekiya, Tomohisa Shoko, Yasuhiro Otomo
BACKGROUND: The purpose of this study was to identify computed tomography (CT) findings that predict the need for angioembolization in patients with pelvic fracture. METHODS: This retrospective cross-sectional study was performed between April 2006 and October 2015 at two urban emergency medical centers in Japan. The study included patients who underwent CT within 3 hours of arrival and were diagnosed with a pelvic fracture. The study outcome was undergoing angioembolization within 24 hours of arrival...
November 14, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29135387/effect-on-bone-architecture-of-marginal-grooves-in-dental-implants-under-occlusal-loaded-conditions-in-beagle-dogs
#5
Hatsumi Kato, Shinichiro Kuroshima, Nao Inaba, Yusuke Uto, Takashi Sawase
The aim was to clarify whether marginal grooves on dental implants affect osseointegration, bone structure and the alignment of collagen fibers determining bone quality under loaded condition. Anodized Ti-6Al-4V alloy dental implants with and without marginal grooves were used (3.7 × 8.0 mm; test and control implants, respectively). Fourth premolars and first molars of six beagle mandibles were extracted. Two control and test implants were placed in randomly selected healed sites at 12 weeks after tooth extraction...
November 14, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29131615/ir4-co-12-catalyzed-benzylic-c-sp3-h-silylation-of-2-alkylpyridines-with-hydrosilanes-leading-to-2-1-silyl-alkylpyridines
#6
Yoshiya Fukumoto, Masaya Hirano, Nao Matsubara, Naoto Chatani
The iridium-catalyzed C(sp3)-H silylation of 2-alkylpyridines with hydrosilanes at the benzylic position to afford 2-(1-silyl)alkylpyridines is described. The low product yield was markedly improved by adding 3,5-dimethylpyridine. Norbornene is also essential additives for the reaction to proceed as a hydrogen scavenger. Carbon monoxide plays an important role in the catalytic cycle as a ligand. Other transition metal carbonyls such as Rh4(CO)12 and Ru3(CO)12 can also be used as catalysts for this C-H silylation...
November 13, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29128287/functional-evaluation-of-swallowing-in-patients-with-tongue-cancer-before-and-after-surgery-using-high-speed-continuous-magnetic-resonance-imaging-based-on-t2-weighted-sequences
#7
Shun Nishimura, Tatsurou Tanaka, Masafumi Oda, Manabu Habu, Masaaki Kodama, Daigo Yoshiga, Kenji Osawa, Shinya Kokuryo, Ikuya Miyamoto, Shinji Kito, Nao Wakasugi-Sato, Shinobu Matsumoto-Takeda, Takaaki Joujima, Yuichi Miyamura, Suzuro Hitomi, Noriaki Yamamoto, Masataka Uehara, Masaaki Sasaguri, Kentaro Ono, Izumi Yoshioka, Kazuhiro Tominaga, Yasuhiro Morimoto
OBJECTIVES: The aim of this study was to determine the usefulness of evaluating the function of swallowing before and after surgery in patients with tongue cancer by using T2-weighted sequences of high-speed continuous magnetic resonance imaging (HSCMRI). STUDY DESIGN: The imaging findings and related parameters on HSCMRI along with those on routine MRI examinations before and after surgery were examined in 19 patients with tongue cancer. In addition, changes in various parameters during 1 year after surgery were evaluated in 10 patients...
October 9, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29123188/spatio-temporal-trends-in-crop-damage-inform-recent-climate-mediated-expansion-of-a-large-boreal-herbivore-into-an-agro-ecosystem
#8
Michel P Laforge, Nicole L Michel, Ryan K Brook
Large-scale climatic fluctuations have caused species range shifts. Moose (Alces alces) have expanded their range southward into agricultural areas previously not considered moose habitat. We found that moose expansion into agro-ecosystems is mediated by broad-scale climatic factors and access to high-quality forage (i.e., crops). We used crop damage records to quantify moose presence across the Canadian Prairies. We regressed latitude of crop damage against North Atlantic Oscillation (NAO) and crop area to test the hypotheses that NAO-mediated wetland recharge and occurrence of more nutritious crop types would result in more frequent occurrences of crop damage by moose at southerly latitudes...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29122576/intracellular-diminazene-aceturate-content-and-adenosine-incorporation-in-diminazene-aceturate-resistant-babesia-gibsoni-isolate-in%C3%A2-vitro
#9
Masahiro Yamasaki, Nao Watanabe, Natsuki Idaka, Tohru Yamamori, Ken-Ichi Otsuguro, Naohiro Uchida, Aiko Iguchi, Hiroshi Ohta, Mitsuyoshi Takiguchi
The mechanism of the development of diminazene aceturate (DA) resistance in Babesia gibsoni is still unknown even though DA-resistant B. gibsoni isolate was previously developed in vitro. To clarify the mechanisms of DA-resistance in B. gibsoni, we initially examined the intracellular DA content in the DA-resistant isolate using high-performance liquid chromatography, and compared it with that in the wild-type. As a result, the intracellular DA content in the DA-resistant isolate was significantly lower than that in the wild-type, suggesting that the decreased DA content may contribute to DA-resistance...
November 6, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/29121986/farm-level-risk-factors-for-fasciola-hepatica-infection-in-danish-dairy-cattle-as-evaluated-by-two-diagnostic-methods
#10
Nao Takeuchi-Storm, Matthew Denwood, Tina Vicky Alstrup Hansen, Tariq Halasa, Erik Rattenborg, Jaap Boes, Heidi Larsen Enemark, Stig Milan Thamsborg
BACKGROUND: The prevalence of bovine fasciolosis in Denmark is increasing but appropriate guidelines for control are currently lacking. In order to help develop a control strategy for liver fluke, a risk factor study of farm management factors was conducted and the utility of bulk tank milk (BTM ELISA) as a tool for diagnosis in Danish dairy cattle farms was assessed. METHODS: This case-control study aimed to identify farm-level risk factors for fasciolosis in Danish dairy farms (> 50 animals slaughtered in 2013) using two diagnostic methods: recordings of liver condemnation at slaughter, and farm-level Fasciola hepatica antibody levels in BTM...
November 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29119097/skeletal-anchorage-for-intrusion-of-bimaxillary-molars-in-a-patient-with-skeletal-open-bite-and-temporomandibular-disorders
#11
Akihiko Iwasa, Shinya Horiuchi, Nao Kinouchi, Takashi Izawa, Masahiro Hiasa, Nobuhiko Kawai, Akihiro Yasue, Ali H Hassan, Eiji Tanaka
The treatment of severe skeletal anterior open bite is extremely difficult in adults, and orthognathic surgery is generally selected for its treatment. We report the case of an 18-year-old adult patient with skeletal anterior open bite and temporomandibular disorders who was successfully treated using temporary anchorage devices. She had an open bite of -2.0 mm and an increased facial height. Miniplates were implanted in both the maxilla and mandible, and molar intrusion resulted in counterclockwise rotation of the mandible over a period of 12 months...
October 2017: Journal of Orthodontic Science
https://www.readbyqxmd.com/read/29111281/association-between-alcohol-consumption-and-incidence-of-impaired-insulin-secretion-and-insulin-resistance-in-japanese-the-saku-study
#12
Yukako Tatsumi, Akiko Morimoto, Kei Asayama, Nao Sonoda, Naomi Miyamatsu, Yuko Ohno, Yoshihiro Miyamoto, Satoshi Izawa, Takayoshi Ohkubo
AIMS: To investigate the effect of alcohol consumption on impaired insulin secretion and insulin resistance in Japanese. METHODS: The participants in this 5-year cohort study were 2100 Japanese aged 30-74 years without type 2 diabetes mellitus, impaired insulin secretion, or insulin resistance who underwent a medical checkup including 75-g OGTT between April 2008 and March 2009 at Saku Central Hospital. Alcohol consumption was categorized as follows: non-drinker (0 g/week), light drinker (1-139 g/week in men and 1-69 g/week in women), moderate drinker (140-274 g/week in men and 70-139 g/week in women) and heavy drinker (≥275 g/week in men and ≥140 g/week in women)...
October 28, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29105509/the-role-of-feature-based-discrimination-in-driving-health-disparities-among-black-americans
#13
Randl B Dent, Nao Hagiwara, Elena V Stepanova, Tiffany L Green
OBJECTIVE: A growing body of research finds that darker skin tone is often associated with poorer physical and mental health in Blacks. However, the psychosocial mechanisms underlying the skin tone-health link remain elusive. The present study seeks to address this knowledge gap by investigating the direct and indirect (through perceived discrimination, socioeconomic status, and self-esteem) effects of skin tone on self-reported physical and mental health. DESIGN: An urban sample of 130 Blacks aged 35 and above completed a self-administered computerized survey as a part of larger cross-sectional study...
November 6, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/29104667/promotion-of-anoxia-reoxygenation-induced-inflammation-and-permeability-enhancement-by-nicotinamide-phosphoribosyltransferase-activated-mapk-signaling-in-human-umbilical-vein-endothelial-cells
#14
Nao Yan, Wei Yang, Xiao Dong, Qiao Fang, Yi Gong, Jian-Liang Zhou, Jian-Jun Xu
Previous studies have demonstrated that nicotinamide phosphoribosyltransferase (NAMPT) promoted inflammation and permeability of vascular endothelial cells following cardiopulmonary bypass (CPB). In addition, mitogen-activated protein kinase (MAPK) signaling was activated and contributed to these cell responses. However, the mechanism by which NAMPT regulates cellular inflammation and permeability remains unknown, and whether NAMPT regulates MAPK signaling during this process is also not clear. The present study established an anoxia-reoxygenation (A-R) model using human umbilical vein endothelial cells (HUVECs) and investigated the regulation of MAPK signaling by NAMPT by using small RNA transfection, ELISA and western blot analysis...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29101095/smartphone-cognitive-behavioral-therapy-as-an-adjunct-to-pharmacotherapy-for-refractory-depression-randomized-controlled-trial
#15
Akio Mantani, Tadashi Kato, Toshi A Furukawa, Masaru Horikoshi, Hissei Imai, Takahiro Hiroe, Bun Chino, Tadashi Funayama, Naohiro Yonemoto, Qi Zhou, Nao Kawanishi
BACKGROUND: In the treatment of major depression, antidepressants are effective but not curative. Cognitive behavioral therapy (CBT) is also effective, alone or in combination with pharmacotherapy, but accessibility is a problem. OBJECTIVE: The aim is to evaluate the effectiveness of a smartphone CBT app as adjunctive therapy among patients with antidepressant-resistant major depression. METHODS: A multisite, assessor-masked, parallel-group randomized controlled trial was conducted in 20 psychiatric clinics and hospitals in Japan...
November 3, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29099658/laparoscopic-hepatic-resection-using-extracorporeal-pringle-maneuver
#16
Yoshihiro Inoue, Yusuke Suzuki, Kensuke Fujii, Nao Kawaguchi, Masatsugu Ishii, Shinsuke Masubuchi, Masashi Yamamoto, Fumitoshi Hirokawa, Michihiro Hayashi, Kazuhisa Uchiyama
BACKGROUND: Laparoscopic hepatic resection (LHR) has been developed as a novel minimally invasive surgery. However, despite improvements in equipment and procedures, intraoperative hemorrhage remains an issue that requires great precaution. To reduce the amount of intraoperative blood loss, we perform the Pringle maneuver, aimed at occluding the inflow of blood into the liver during LHR. This article describes our experience performing LHR using the Pringle maneuver, including postoperative results, and discusses the safety and effectiveness of the Pringle maneuver...
November 3, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29099287/pax5-gene-as-a-novel-methylation-marker-that-predicts-both-clinical-outcome-and-cisplatin-sensitivity-in-esophageal-squamous-cell-carcinoma
#17
Keisuke Kurimoto, Masamichi Hayashi, Rafael Guerrero-Preston, Masahiko Koike, Mitsuro Kanda, Sho Hirabayashi, Hiroshi Tanabe, Nao Takano, Naoki Iwata, Yukiko Niwa, Hideki Takami, Daisuke Kobayashi, Chie Tanaka, Suguru Yamada, Goro Nakayama, Hiroyuki Sugimoto, Tsutomu Fujii, Michitaka Fujiwara, Yasuhiro Kodera
Therapeutic strategies for esophageal cancer largely depend on histopathological assessment. To select appropriate treatments for individual patients, we examined the background molecular characteristics of tumor malignancy and sensitivity to multidisciplinary therapy. Seventy-eight surgically-resected esophageal squamous cell carcinoma (ESCC) cases during 2001-2013 were examined. PAX5, a novel gene methylation marker in ESCC, was evaluated in the specimens, as methylation of this gene was identified as an extremely tumor-specific event in squamous cell carcinogenesis of head and neck...
November 3, 2017: Epigenetics: Official Journal of the DNA Methylation Society
https://www.readbyqxmd.com/read/29097542/lattice-system-of-functionally-distinct-cell-types-in-the-neocortex
#18
Hisato Maruoka, Nao Nakagawa, Shun Tsuruno, Seiichiro Sakai, Taisuke Yoneda, Toshihiko Hosoya
The mammalian neocortex contains many cell types, but whether they organize into repeated structures has been unclear. We discovered that major cell types in neocortical layer 5 form a lattice structure in many brain areas. Large-scale three-dimensional imaging revealed that distinct types of excitatory and inhibitory neurons form cell type-specific radial clusters termed microcolumns. Thousands of microcolumns, in turn, are patterned into a hexagonal mosaic tessellating diverse regions of the neocortex. Microcolumn neurons demonstrate synchronized in vivo activity and visual responses with similar orientation preference and ocular dominance...
November 3, 2017: Science
https://www.readbyqxmd.com/read/29097424/the-free-fatty-acid-receptor-1-promotes-airway-smooth-muscle-cell-proliferation-through-mek-erk-and-pi3k-akt-signaling-pathways
#19
Atsuko Matoba, Nao Matsuyama, Sumire Shibata, Eiji Masaki, Charles W Emala, Kentaro Mizuta
Obesity is a risk factor for asthma and influences airway hyperresponsiveness, which is in part modulated by airway smooth muscle proliferative remodeling. Plasma free fatty acids (FFAs) levels are elevated in obese individuals, and long-chain FFAs act as endogenous ligands for the free fatty acid receptor 1 (FFAR1), which couples to both Gq and Gi proteins. We examined whether stimulation of FFAR1 induces airway smooth muscle cell proliferation through classical MEK/ERK and/or PI3K/Akt signaling pathways. The long-chain FFAs (oleic acid and linoleic acid) and a FFAR1 agonist (GW9508) induced human airway smooth muscle (HASM) cell proliferation, which was inhibited by the MEK inhibitor U0126 and the PI3K inhibitor LY294002...
November 2, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/29084372/a-phase-i-ii-exploratory-clinical-trial-for-intracordal-injection-of-recombinant-hepatocyte-growth-factor-for-vocal-fold-scar-and-sulcus
#20
Shigeru Hirano, Atsuhiko Kawamoto, Ichiro Tateya, Masanobu Mizuta, Yo Kishimoto, Nao Hiwatashi, Yoshitaka Kawai, Takuya Tsuji, Ryo Suzuki, Mami Kaneko, Yasushi Naito, Tatsuo Kagimura, Tatsuo Nakamura, Shin-Ichi Kanemaru
BACKGROUND: Vocal fold scar and sulcus are intractable diseases with no effective established treatments. Hepatocyte growth factor (HGF) has preclinically proven to have potent anti-fibrotic and regenerative effects on vocal fold scar. The current phase I/II clinical trial aims to examine the safety and effectiveness of intracordal injection of a recombinant human HGF drug for patients with vocal fold scar or sulcus. STUDY DESIGN: Phase I/II, open-label, dose-escalating, first-in-human clinical trial...
October 30, 2017: Journal of Tissue Engineering and Regenerative Medicine
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