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https://www.readbyqxmd.com/read/28635301/stem-cell-mediated-paracrine-signaling-alters-fibroplasia-in-human-vocal-fold-fibroblasts-in-vitro
#1
Nao Hiwatashi, Renjie Bing, Iv Kraja, Ryan C Branski
OBJECTIVES: Interactions between mesenchymal stem cells (MSCs) and native vocal fold fibroblasts (VFFs) have not been described in spite of promising preliminary data regarding the effects of MSCs on vocal fold repair in vivo. The current study employed a conditioned media (CM) model to investigate the paracrine effects of bone marrow-derived mesenchymal stem cells (BMSCs) on VFFs. METHODS: Human VFFs were treated with transforming growth factor-β1 (TGF-β1; 10 ng/mL), CM from human BMSCs following 48 hours of TGF-β1 stimulation, or CM+TGF-β1...
June 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28630446/strong-sub-seasonal-wintertime-cooling-over-east-asia-and-northern-europe-associated-with-super-el-ni%C3%A3-o-events
#2
Xin Geng, Wenjun Zhang, Malte F Stuecker, Fei-Fei Jin
East Asia experienced a record-breaking cold event during the 2015/16 boreal winter, with pronounced impacts on livelihood in the region. We find that this large-scale cold spell can be attributed to the concurrent super El Niño event in the tropical Pacific. Our analysis reveals that all super El Niño winters (1982/83, 1997/98, and 2015/16) were accompanied by a rapid sub-seasonal North Atlantic Oscillation (NAO)/Arctic Oscillation (AO) phase reversal from a positive to a negative state during early January, which was largely caused by the interaction of these super El Niño events with the subtropical jet annual cycle...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28627575/label-free-detection-of-aggregated-platelets-in-blood-by-machine-learning-aided-optofluidic-time-stretch-microscopy
#3
Yiyue Jiang, Cheng Lei, Atsushi Yasumoto, Hirofumi Kobayashi, Yuri Aisaka, Takuro Ito, Baoshan Guo, Nao Nitta, Natsumaro Kutsuna, Yasuyuki Ozeki, Atsuhiro Nakagawa, Yutaka Yatomi, Keisuke Goda
According to WHO, about 10 million new cases of thrombotic disorders are diagnosed worldwide every year. Thrombotic disorders, including atherothrombosis (the leading cause of death in the US and Europe), are induced by occlusion of blood vessels, due to the formation of blood clots in which aggregated platelets play an important role. The presence of aggregated platelets in blood may be related to atherothrombosis (especially acute myocardial infarction) and is, hence, useful as a potential biomarker for the disease...
June 19, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28626308/relationship-between-trunk-function-evaluated-using-the-trunk-righting-test-and-physical-function-in-patients-with-knee-osteoarthritis
#4
Kazuaki Kinoshita, Kazunari Ishida, Masashi Hashimoto, Yuki Yoneda, Yuta Naka, Hideyuki Kitanishi, Hiroki Oyagi, Yuichi Hoshino, Masahiro Kurosaka, Nao Shibanuma
[Purpose] The present study was to validate the importance of the trunk function evaluated by trunk righting test (TRT) with motor function in patients with knee osteoarthritis (OA) and to show the clinical use of TRT. [Subjects and Methods] This study included 50 patients with knee osteoarthritis who underwent total knee arthroplasty in our hospital. Correlations between physical functional test, such as muscle strength, balance function, and performance and TRT were statistically evaluated. [Results] The independent factors for ipsilateral TRT were maximal isometric knee extensor strength test and ipsilateral step test...
June 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28615967/assessment-of-direct-analgesic-effect-of-duloxetine-for-chronic-low-back-pain-post-hoc-path-analysis-of-double-blind-placebo-controlled-studies
#5
Hiroyuki Enomoto, Shinji Fujikoshi, Jumpei Funai, Nao Sasaki, Michael H Ossipov, Toshinaga Tsuji, Levent Alev, Takahiro Ushida
BACKGROUND: Comorbid depression and depressive symptoms are common in patients with chronic low back pain (CLBP). Duloxetine is clinically effective in major depressive disorder and several chronic pain states, including CLBP. The objective of this post hoc meta-analysis was to assess direct and indirect analgesic efficacy of duloxetine for patients with CLBP in previous clinical trials. METHODS: Post hoc path analyses were conducted of 3 randomized, double-blind, clinical studies of patients receiving duloxetine or placebo for CLBP...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28614441/prevalence-and-factors-associated-with-minor-psychiatric-disorders-in-hospital-housekeeping-workers
#6
Cintia da Silva Marconato, Ana Carolina de Souza Magnago, Tânia Solange Bosi de Souza Magnago, Graziele de Lima Dalmolin, Rafaela Andolhe, Juliana Petri Tavares
OBJECTIVE: Investigating the prevalence and factors associated with minor psychiatric disorders (MPDs) in Hospital housekeeping workers. METHOD: A cross-sectional study carried out in 2013 with workers from the cleaning service of a public university hospital in Rio Grande do Sul, Brazil. Data were collected through a form containing sociodemographic, occupational, habits and health variables. The Self-Reporting Questionnaire-20 was used in order to evaluate MPDs...
June 12, 2017: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28614439/residual-volume-in-vials-of-antibiotics-used-in-pediatrics
#7
Caroline Magna Pessoa Chaves, Carolina Martins Bezerra, Francisca Elisângela Teixeira Lima, Maria Vera Lúcia Moreira Leitão Cardoso, Said Gonçalves da Cruz Fonseca, Viviane Martins da Silva
OBJECTIVE: Quantifying residual volume contained in vials of antibiotics used in pediatrics. METHOD: This is an experiment involving samples from vials of antibiotics used in a pediatric hospital. Residual volume was identified by calculating the difference in weight measurement before and after the vials were washed. Evaluation of the residual volume difference in the vials was determined by the Wilcoxon non-parametric test for a sample and established at a significance level of 5%...
June 12, 2017: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28614428/intrapancreatic-accessory-spleen
#8
Marcelo Protásio Dos Santos, Aline Pacheco de Rezende, Paulo Vicente Dos Santos, José Eduardo Gonçalves, Fernando Bray Beraldo, Adriano Pereira Sampaio
An asymptomatic 79-year-old woman, with incidental finding on abdominal ultrasound of a solid nodule in the tail of the pancreas. Magnetic resonance imaging showed a 12mm solid tumor. The suggested diagnosis was pancreatic neuroendocrine tumor. The pathological examination showed an intrapancreatic splenic tissue. This is a rare ectopic location of spleen tissue and it should be considered in the differential diagnosis of pancreatic solid tumors. RESUMO Mulher de 79 anos, com achado incidental em ultrassonografia de abdome de lesão sólida em cauda de pâncreas...
June 12, 2017: Einstein
https://www.readbyqxmd.com/read/28608417/otolaryngology-practice-patterns-in-pediatric-tonsillectomy-the-impact-of-the-codeine-boxed-warning
#9
Julie L Goldman, Craig Ziegler, Elizabeth M Burckardt
OBJECTIVES/HYPOTHESIS: To determine if otolaryngologists at a single children's hospital were adherent to the boxed warning for codeine use in post-tonsillectomy patients and the implications for practice patterns. STUDY DESIGN: Case series with chart review. METHODS: Charts from all patients undergoing adenotonsillectomy at a single children's hospital from January 1, 2010 through December 31, 2015 were analyzed and stratified according to date (pre- or post-boxed warning) and practitioner type (academic otolaryngologists [AO] vs...
June 13, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28604332/microbacterium-tumbae-sp-nov-an-actinobacterium-isolated-from-the-stone-chamber-of-ancient-tumulus
#10
Miyuki Nishijima, Nozomi Tazato, Yutaka Handa, Nao Umekawa, Rika Kigawa, Chie Sano, Junta Sugiyama
Eight strains characterised as Gram-stain-positive, non-spore-forming and non-motile rods were isolated from samples collected from stone chambers of the Takamatsuzuka and Kitora tumuli in Asuka village, Nara Prefecture, Japan. Among them, one strain, T7528-3-6bT, was shown to form a novel lineage within the genus Microbacterium. The most closely phylogenetically related species to T7528-3-6bT was Microbacterium panaciterrae, with 97.8 % sequence similarity. The major isoprenoid quinones of T7528-3-6bT were MK-12, MK-13 and MK-11...
June 13, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28599498/sequential-administration-of-xelox-and-xeliri-is-effective-feasible-and-well-tolerated-by-patients-with-metastatic-colorectal-cancer
#11
Taro Fukui, Koichi Suzuki, Kosuke Ichida, Yuji Takayama, Nao Kakizawa, Yuta Muto, Fumi Hasegawa, Fumiaki Watanabe, Rina Kikugawa, Masaaki Saito, Shingo Tsujinaka, Yasuyuki Miyakura, Toshiki Rikiyama
Sequential administration of the chemotherapy regimes capecitabine and oxaliplatin (XELOX) and capecitabine and irinotecan (XELIRI) in the first- to second-line treatment setting would allow patients to be managed more easily in an outpatient unit. However, a small number of studies have raised concerns of cumulative adverse events as a consequence of the continuous use of capecitabine. To investigate this, the present study conducted a retrospective review of 81 consecutive metastatic colorectal cancer (mCRC) patients treated with the oxaliplatin, fluorouracil and leucovorin-irinotecan, fluorouracil and leucovorin (FOLFOX-FOFIRI/F-F) regimen (n=40) or the XELOX-XELIRI (X-X) regimen (n=41) in first- to second-line chemotherapy in Saitama Medical Center between 2006 and 2012...
June 2017: Oncology Letters
https://www.readbyqxmd.com/read/28596270/timing-of-post-exercise-carbohydrate-protein-supplementation-roles-of-gastrointestinal-blood-flow-and-mucosal-cell-damage-on-gastric-emptying-in-humans
#12
Hideaki Kashima, Nao Harada, Kanae Miyamoto, Masaki Fujimoto, Chiaki Fujita, Masako Yamaoka Endo, Toshio Kobayashi, Akira Miura, Yoshiyuki Fukuba
It is well known that protein ingestion immediately after exercise greatly stimulates muscle protein synthesis during the post-exercise recovery phase. However, immediately after strenuous exercise, the gastrointestinal (GI) mucosa is frequently injured by hypoperfusion in the organ/tissue, possibly resulting in impaired GI function (e.g., gastric emptying; GE). The aim of this study was to examine the effect of GI blood flow on the GE rate. Eight healthy young subjects performed an intermittent supramaximal cycling exercise for 30 min, which consisted of a 120% VO2 peak for 20 s, followed by 20 W for 40 s...
June 8, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28591358/factor-associated-with-self-reported-work-related-musculoskeletal-disorders-in-brazilian-adults
#13
Ada Ávila Assunção, Mery Natali Silva Abreu
OBJECTIVE: To describe the prevalence of work-related musculoskeletal disorder (WMSD) and analyze the factors associated with this outcome in the Brazilian population. METHODS: In this cross-sectional, population-based study, we use data from the National Survey on Health (PNS) of 2013. The sample was composed of 60,202 Brazilians aged 18 years or older. The outcome variable was the occurrence of self-reported WMSD. Sociodemographic and occupational characteristics, personal resources, and health conditions were investigated as explanatory variables...
June 1, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28591356/early-detection-of-breast-cancer-in-brazil-data-from-the-national-health-survey-2013
#14
Gulnar Azevedo E Silva, Paulo Roberto Borges de Souza-Júnior, Giseli Nogueira Damacena, Célia Landmann Szwarcwald
OBJECTIVE: To analyze whether the actions of early detection of breast cancer, initiated with the medical request for mammography, differ between users of the Brazilian Unified Health System (SUS) and those who have private health insurance. METHODS: From the data collected in the National Health Survey, we estimated the proportions of women who had medical request for mammography according to presence or absence of private health insurance. For assessing the factors related to having mammography medical request, we estimated crude and adjusted odds ratios and respective 95%CI by logistic regression...
June 1, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28591354/inequalities-in-healthy-life-expectancy-by-federated-states
#15
Célia Landmann Szwarcwald, Dália Elena Romero Montilla, Aline Pinto Marques, Giseli Nogueira Damacena, Wanessa da Silva de Almeida, Deborah Carvalho Malta
OBJECTIVES: To estimate the healthy life expectancy at 60 years by sex and Federated States and to investigate geographical inequalities by socioeconomic status. METHODS: Healthy life expectancy was estimated by the Sullivan method, based on the information of the National Survey on Health, 2013. Three criteria were adopted for the definition of "unhealthy state": self-assessment of bad health, functionality for performing the activities of daily living, and the presence of noncommunicable disease with intense degree of limitation...
June 1, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28591353/noncommunicable-diseases-and-the-use-of-health-services-analysis-of-the-national-health-survey-in-brazil
#16
Deborah Carvalho Malta, Regina Tomie Ivata Bernal, Margareth Guimarães Lima, Silvânia Suely Caribé de Araújo, Marta Maria Alves da Silva, Maria Imaculada de Fátima Freitas, Marilisa Berti de Azevedo Barros
OBJECTIVE: To assess whether sex, education level, and health insurance affect the use of health services among the adult Brazilian population with chronic noncommunicable diseases (NCD). METHODS: Data from a cross-sectional survey were analyzed, the National Health Survey (PNS). Frequency of use of services in the population that referred at least one NCD were compared with the frequency from a population that did not report NCD, according to sex, education level, health insurance, and NCD number (1, 2, 3, 4, or more)...
June 1, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28591352/depression-and-health-behaviors-in-brazilian-adults-pns-2013
#17
Marilisa Berti de Azevedo Barros, Margareth Guimarães Lima, Renata Cruz Soares de Azevedo, Lhais Barbosa de Paula Medina, Claudia de Souza Lopes, Paulo Rossi Menezes, Deborah Carvalho Malta
OBJECTIVE: To evaluate the prevalence of health-related behaviors according to presence and type of depression in Brazilian adults. METHODS: Based on a sample of 49,025 adults (18 to 59 years) from the National Survey on Health 2013 (PNS 2013), we estimated the prevalence of health-related behaviors (smoking; passive smoking; frequent or risky alcohol consumption; leisure time physical activity; time watching TV; and eating pattern indicators), according to the presence of depression (minor and major), evaluated by the Patient Health Questionnaire - 9 (PHQ-9), and the report of depressive mood (in up to seven days or more than seven days) over a two-week period...
June 1, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28591351/use-of-and-access-to-health-services-in-brazil-2013-national-health-survey
#18
Sheila Rizzato Stopa, Deborah Carvalho Malta, Camila Nascimento Monteiro, Célia Landmann Szwarcwald, Moisés Goldbaum, Chester Luiz Galvão Cesar
OBJECTIVE: To analyze the use of health services in the Brazilian population by sociodemographic factors, according to data from the 2013 Brazilian National Health Survey. METHODS: The study analyzed data from 205,000 Brazilian citizens in all age groups who participated in the Brazilian National Health Survey, a cross-sectional study carried out in 2013. Prevalence and confidence intervals were estimated for indicators related to access to and use of health services according to age group, level of education of head of household, and Brazilian macroregions...
June 1, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28591349/family-influence-on-the-consumption-of-sugary-drinks-by-children-under-two-years-old
#19
Patricia Constante Jaime, Rogério Ruscitto do Prado, Deborah Carvalho Malta
OBJECTIVE: To evaluate the influence of family habits and household characteristics on the consumption of sugary drinks by Brazilian children under two years old. METHODS: This was a cross-sectional study that used secondary data generated by the National Health Survey (PNS) in 2013. We studied 4,839 pairs of children under two years old and adults living in the same house. We estimated the prevalence of the indicator of sugary drinks consumption for the total sample of children and according to family and household variables...
June 1, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28591348/informal-and-paid-care-for-brazilian-older-adults-national-health-survey-2013
#20
Maria Fernanda Lima-Costa, Sérgio Viana Peixoto, Deborah Carvalho Malta, Célia Landmann Szwarcwald, Juliana Vaz de Melo Mambrini
OBJECTIVE: To describe the prevalence and sociodemographic factors associated with informal and paid care for Brazilian older adults with functional limitations. METHODS: Of the 23,815 participants of the National Health Survey aged 60 or older, 5,978 reported needing help to perform activities of daily living and were included in this analysis. The dependent variable was the source of care, categorized as exclusively informal (unpaid), exclusively formal (paid), mixed or none...
June 1, 2017: Revista de Saúde Pública
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