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https://www.readbyqxmd.com/read/28204956/centrally-targeted-pharmacotherapy-for-chronic-abdominal-pain-understanding-and-management
#1
Hans Törnblom, Douglas A Drossman
Chronic abdominal pain has a widespread impact on the individual and the society. Identifying and explaining mechanisms of importance for the pain experience within a biopsychosocial context are central in order to select treatment that has a chance for symptom reduction. With current knowledge of brain-gut interactions, chronic abdominal pain, which mostly appears in functional gastrointestinal disorders, to a large extent involves pain mechanisms residing within the brain. As such, the use of centrally targeted pharmacotherapy as an effective treatment option is obvious in a selected number of patients...
February 16, 2017: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/28202233/practice-makes-perfect-a-systematic-review-of-the-expertise-development-of-pharmacist-and-nurse-independent-prescribers-in-the-united-kingdom
#2
REVIEW
Aseel S Abuzour, Penny J Lewis, Mary P Tully
BACKGROUND: Prescribing is a complex and error-prone task that demands expertise. McLellan et al.'s theory of expertise development model ("the model"), developed to assess medical literature on prescribing by medical students, proposes that in order to develop, individuals should deliberately engage their knowledge, skills and attitudes within a social context. Its applicability to independent prescribers (IP) is unknown. AIM: A systematic review was conducted to explore whether the model is applicable to non-medical independent prescribing and to assess the factors underpinning expertise development reported in the literature...
February 7, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28199800/preventive-biomechanics
#3
Timothy E Hewett, Nathaniel A Bates
BACKGROUND: Preventive medicine techniques have alleviated billions of dollars' worth of the economic burden in the medical care system through the implementation of vaccinations and screenings before the onset of disease symptoms. Knowledge of biomechanical tendencies has progressed rapidly over the past 20 years such that clinicians can identify, in healthy athletes, the underlying mechanisms that lead to catastrophic injuries such as anterior cruciate ligament (ACL) ruptures. As such, preventive medicine concepts can be applied to noncontact musculoskeletal injuries to reduce the economic burden of sports medicine treatments and enhance the long-term health of athletes...
February 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28194523/-establishment-of-the-new-cross-sectional-field-of-pain-medicine-an-application-example-at-the-medical-faculty-of-heidelberg
#4
S Frankenhauser, T Böker-Blum, C Busch, C Berberich, A L Mihaljevic, M A Weigand, H J Bardenheuer, J Kessler
Studies from recent years paint a picture of qualitatively deficient treatment in pain medicine. In order to improve the situation knowledge on targeted diagnostics and effective therapy should be imparted at an early stage during undergraduate studies. For this reason the cross-sectional field Q14 - pain medicine was newly created in the revision of the medical physician licencing regulations. The Q14 was then established in a longitudinal, multidisciplinary form at the medical faculty in Heidelberg, whereby the complete Kern cycle was run through...
February 13, 2017: Der Schmerz
https://www.readbyqxmd.com/read/28178916/development-of-an-interdisciplinary-pre-matriculation-program-designed-to-promote-medical-students-self-efficacy
#5
Anna Wirta Kosobuski, Abigail Whitney, Andrew Skildum, Amy Prunuske
BACKGROUND AND OBJECTIVES: A four-week interdisciplinary pre-matriculation program for Native American and rural medical students was created and its impact on students' transition to medical school was assessed. The program extends the goals of many pre-matriculation programs by aiming to increase not only students' understanding of basic science knowledge, but also to build student self-efficacy through practice with medical school curricular elements while developing their academic support networks...
2017: Medical Education Online
https://www.readbyqxmd.com/read/28178915/the-relationship-between-the-monitored-performance-of-tutors-and-students-at-pbl-tutorials-and-the-marked-hypotheses-generated-by-students-in-a-hybrid-curriculum
#6
Jonas I Addae, Pradeep Sahu, Bidyadhar Sa
INTRODUCTION: There have been a number of published studies examining the link between the effectiveness of the problem-based learning (PBL) process and students' performance in examinations. In a hybrid PBL/lectures curriculum, the results of such studies are of limited use because of the difficulty in dissociating the knowledge gained at lectures from that gained through PBL-related activities. Hence, the objectives of this study were: (1) to develop an instrument to measure the performance of tutors and students at PBL tutorials, and (2) to explore the contribution of such performances to the marks attained by students from the hypotheses generated at PBL tutorials...
2017: Medical Education Online
https://www.readbyqxmd.com/read/28176890/contextualizing-the-relevance-of-basic-sciences-small-group-simulation-with-debrief-for-first-and-second-year-medical-students-in-an-integrated-curriculum
#7
Samara B Ginzburg, Judith Brenner, Michael Cassara, Thomas Kwiatkowski, Joanne M Willey
AIM: There has been a call for increased integration of basic and clinical sciences during preclinical years of undergraduate medical education. Despite the recognition that clinical simulation is an effective pedagogical tool, little has been reported on its use to demonstrate the relevance of basic science principles to the practice of clinical medicine. We hypothesized that simulation with an integrated science and clinical debrief used with early learners would illustrate the importance of basic science principles in clinical diagnosis and management of patients...
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/28160371/effect-of-immersive-workplace-experience-on-undergraduate-nurses-mental-health-clinical-confidence
#8
Christopher Patterson, Lorna Moxham, Ellie K Taylor, Dana Perlman, Renee Brighton, Susan Sumskis, Tim Heffernan, Benjamin Lee-Bates
Preregistration education needs to ensure that student nurses are properly trained with the required skills and knowledge, and have the confidence to work with people who have a mental illness. With increased attention on non-traditional mental health clinical placements, further research is required to determine the effects of non-traditional mental health clinical placements on mental health clinical confidence. The aim of the present study was to investigate the impact of a non-traditional mental health clinical placement on mental health nursing clinical confidence compared to nursing students undergoing traditional clinical placements...
February 3, 2017: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/28157421/procedural-simulations-and-reflective-practice-meeting-the-need
#9
Sarah Sullivan, Andrew Ruis, Carla Pugh
The medical profession continues to learn about the ways in which simulations can help to improve education and training. In addition, simulation is constantly evaluated regarding the many ways it can help to improve the abilities of surgeons throughout their course of training and practice. The goal of this study is to review the importance of reflection on clinical practice in situating surgeons as lifelong learners and explore the role that simulation can play in that process. As surgical trainees work to acquire basic necessary skills, simulations are often used to help new learners with such things as knowledge of procedural steps and development of psychomotor techniques...
February 3, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28149846/parametric-regression-model-for-survival-data-weibull-regression-model-as-an-example
#10
EDITORIAL
Zhongheng Zhang
Weibull regression model is one of the most popular forms of parametric regression model that it provides estimate of baseline hazard function, as well as coefficients for covariates. Because of technical difficulties, Weibull regression model is seldom used in medical literature as compared to the semi-parametric proportional hazard model. To make clinical investigators familiar with Weibull regression model, this article introduces some basic knowledge on Weibull regression model and then illustrates how to fit the model with R software...
December 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28148804/a-microrna-screen-identifies-the-wnt-signaling-pathway-as-a-regulator-of-the-interferon-response-during-flavivirus-infection
#11
Jessica L Smith, Sophia Jeng, Shannon K McWeeney, Alec J Hirsch
: The impact of mosquito-borne flavivirus infections worldwide is significant, and many critical aspects of these viruses' biology, including virus-host interactions, host cell requirements for replication, and how virus-host interactions impact pathology, remain to be fully understood. The recent re-emergence and spread of flaviviruses, including dengue virus (DENV), West Nile virus (WNV), and Zika virus (ZIKV), highlights the importance of performing basic research on this important group of pathogens...
February 1, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28148207/clinical-cancer-advances-2017-annual-report-on-progress-against-cancer-from-the-american-society-of-clinical-oncology
#12
Harold J Burstein, Lada Krilov, Jeanny B Aragon-Ching, Nancy N Baxter, E Gabriela Chiorean, Warren Allen Chow, John Frederick De Groot, Steven Michael Devine, Steven G DuBois, Wafik S El-Deiry, Andrew S Epstein, John Heymach, Joshua Adam Jones, Deborah K Mayer, Rebecca A Miksad, Nathan A Pennell, Michael S Sabel, Richard L Schilsky, Lynn Mara Schuchter, Nadine Tung, Karen Marie Winkfield, Lori J Wirth, Don S Dizon
A MESSAGE FROM ASCO'S PRESIDENT I am pleased to present Clinical Cancer Advances 2017, which highlights the most promising advances in patient-oriented cancer research over the past year. The report gives us an opportunity to reflect on what an exciting time it is for cancer research and how swiftly our understanding of cancer has improved. One year ago, the White House announced the national Cancer Moonshot program to accelerate progress against cancer. This shared vision of progress has reinvigorated the research community, identified new areas of scientific collaboration, and raised our ambitions regarding what may be possible beyond the progress we have already made...
February 1, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28145990/computer-based-medical-education-in-benha-university-egypt-knowledge-attitude-limitations-and-suggestions
#13
Hanaa Bayomy, Mona El Awadi, Eman El Araby, Hala A Abed
BACKGROUND: Computer-assisted medical education has been developed to enhance learning and enable high-quality medical care. This study aimed to assess computer knowledge and attitude toward the inclusion of computers in medical education among second-year medical students in Benha Faculty of Medicine, Egypt, to identify limitations, and obtain suggestions for successful computer-based learning. PARTICIPANTS AND METHODS: This was a one-group pre-post-test study, which was carried out on second-year students in Benha Faculty of Medicine...
December 2016: Journal of the Egyptian Public Health Association
https://www.readbyqxmd.com/read/28145107/a-comprehensive-experiment-for-molecular-biology-determination-of-single-nucleotide-polymorphism-in-human-rev3-gene-using-pcr-rflp
#14
Xu Zhang, Meng Shao, Lu Gao, Yuanyuan Zhao, Zixuan Sun, Liping Zhou, Yongmin Yan, Qixiang Shao, Wenrong Xu, Hui Qian
Laboratory exercise is helpful for medical students to understand the basic principles of molecular biology and to learn about the practical applications of molecular biology. We have designed a lab course on molecular biology about the determination of single nucleotide polymorphism (SNP) in human REV3 gene, the product of which is a subunit of DNA polymerase ζ and SNPs in this gene are associated with altered susceptibility to cancer. This newly designed experiment is composed of three parts, including genomic DNA extraction, gene amplification by PCR, and genotyping by RFLP...
February 1, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28145074/assessment-of-knowledge-of-participants-on-basic-molecular-biology-techniques-after-5-day-intensive-molecular-biology-training-workshops-in-nigeria
#15
J I Yisau, A O Adagbada, T Bamidele, M Fowora, B I C Brai, O Adebesin, M Bamidele, T Fesobi, F O Nwaokorie, A Ajayi, S I Smith
The deployment of molecular biology techniques for diagnosis and research in Nigeria is faced with a number of challenges, including the cost of equipment and reagents coupled with the dearth of personnel skilled in the procedures and handling of equipment. Short molecular biology training workshops were conducted at the Nigerian Institute of Medical Research (NIMR), to improve the knowledge and skills of laboratory personnel and academics in health, research, and educational facilities. Five-day molecular biology workshops were conducted annually between 2011 and 2014, with participants drawn from health, research facilities, and the academia...
February 1, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28144170/flipping-the-classroom-to-teach-millennial-residents-medical-leadership-a-proof-of-concept
#16
Alicia T Lucardie, Lizanne Berkenbosch, Jochem van den Berg, Jamiu O Busari
INTRODUCTION: The ongoing changes in health care delivery have resulted in the reform of educational content and methods of training in postgraduate medical leadership education. Health care law and medical errors are domains in medical leadership where medical residents desire training. However, the potential value of the flipped classroom as a pedagogical tool for leadership training within postgraduate medical education has not been fully explored. Therefore, we designed a learning module for this purpose and made use of the flipped classroom model to deliver the training...
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/28134953/comparison-of-basic-science-knowledge-between-do-and-md-students
#17
Glenn E Davis, Gregory G Gayer
CONTEXT: With the coming single accreditation system for graduate medical education, medical educators may wonder whether knowledge in basic sciences is equivalent for osteopathic and allopathic medical students. OBJECTIVE: To examine whether medical students' basic science knowledge is the same among osteopathic and allopathic medical students. METHODS: A dataset of the Touro University College of Osteopathic Medicine-CA student records from the classes of 2013, 2014, and 2015 and the national cohort of National Board of Medical Examiners Comprehensive Basic Science Examination (NBME-CBSE) parameters for MD students were used...
February 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28131442/the-human-gut-microbiome-as-source-of-innovation-for-health-which-physiological-and-therapeutic-outcomes-could-we-expect
#18
Joël Doré, Marie-Christine Multon, Jehan-Michel Béhier
From the moment of birth, each human being builds a microbe-host symbiosis which is key for the preservation of its health and well-being. This personal symbiotic coexistence is the result of progressive enrichments in microorganism diversity through external supplies. This diversity is nowadays massively overthrown by drastic changes related to clinical practice in birth management, environmental exposure, nutrition and healthcare behaviors. The last two generations have been the frame of massive modifications in life and food habits, with people being more and more sedentary, overfed and permeated with drugs and pollutants...
January 3, 2017: Thérapie
https://www.readbyqxmd.com/read/28130331/metamap-lite-an-evaluation-of-a-new-java-implementation-of-metamap
#19
Dina Demner-Fushman, Willie J Rogers, Alan R Aronson
MetaMap is a widely used named entity recognition tool that identifies concepts from the Unified Medical Language System Metathesaurus in text. This study presents MetaMap Lite, an implementation of some of the basic MetaMap functions in Java. On several collections of biomedical literature and clinical text, MetaMap Lite demonstrated real-time speed and precision, recall, and F1 scores comparable to or exceeding those of MetaMap and other popular biomedical text processing tools, clinical Text Analysis and Knowledge Extraction System (cTAKES) and DNorm...
January 27, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28129720/effective-methods-of-teaching-and-learning-in-anatomy-as-a-basic-science-a-beme-systematic-review-beme-guide-no-44
#20
C Dominique Losco, William D Grant, Anthony Armson, Amanda J Meyer, Bruce F Walker
BACKGROUND: Anatomy is a subject essential to medical practice, yet time committed to teaching is on the decline, and resources required to teach anatomy is costly, particularly dissection. Advances in technology are a potential solution to the problem, while maintaining the quality of teaching required for eventual clinical application. AIM: To identify methods used to teach anatomy, including those demonstrated to enhance knowledge acquisition and retention. METHODS: PubMed, CINAHL, ERIC, Academic OneFile, ProQuest, SAGE journals and Scopus were search from the earliest entry of each database to 31 August 2015...
January 27, 2017: Medical Teacher
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