keyword
MENU ▼
Read by QxMD icon Read
search

R biomedical

keyword
https://www.readbyqxmd.com/read/28643930/moving-towards-precision-orthodontics-an-evolving-paradigm-shift-in-the-planning-and-delivery-of-customized-orthodontic-therapy
#1
REVIEW
A H Jheon, S Oberoi, R C Solem, S Kapila
Advances in precision medicine portend similar progress in orthodontics and will be increasingly harnessed to achieve customized treatment approaches and enhance treatment efficiencies. Our goal is to provide a background on emerging advances in computer technologies and biomedicine and highlight their current and likely future applications to precision orthodontics. A review of orthodontically relevant technologies and advances in pertinent biological research was undertaken. Innovations in computer hardware and software, and 3D imaging technologies offer the ability for customized treatment and biomechanical planning that will be more fully realized within the next few decades...
June 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28643695/highly-fluorescent-and-superparamagnetic-nanosystem-for-biomedical-applications
#2
Mariana P Cabrera, Paulo E Cabral Filho, Camila M C M Silva, Rita M Oliveira, Carlos F G C Geraldes, M Margarida C A Castro, Benilde F O Costa, Marta S C Henriques, José A Paixão, Luiz B Carvalho, Beate S Santos, Fernando Hallwass, Adriana Fontes, Giovannia A L Pereira
This work reports on highly fluorescent and superparamagnetic bimodal nanoparticles (BNPs) obtained by a simple and efficient method as probes for fluorescence analysis and/or contrast agents for MRI. These promising BNPs with small dimensions (ca. 17 nm) consist of superparamagnetic iron oxide nanoparticles (SPIONs) covalently bound with CdTe quantum dots (ca. 3 nm). The chemical structure of the magnetic part of BNPs is predominantly magnetite, with minor goethite and maghemite contributions, as shown by Mössbauer spectroscopy, which is compatible with the x-ray diffraction data...
July 14, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28641018/three-dimensional-imaging-of-transparent-tissues-via-metal-nanoparticle-labeling
#3
Abdullah Muhammad Syed, Shrey Sindhwani, Stefan Wilhelm, Benjamin R Kingston, Dennis S W Lee, Jennifer L Gommerman, Warren C W Chan
Chemical probes are key components of the bioimaging toolbox as they label biomolecules in cells and tissues. The new challenge in bioimaging is to design chemical probes for 3-Dimensional (3D) tissue imaging. Here, we discovered that the scattering of metal nanoparticles can provide imaging contrast in intact tissues in 3D. The nanoparticles can act as a template for chemically growing a metal layer to further enhance the scattering signal. The use of chemically-grown nanoparticles in whole tissues can amplify the scattering to produce a 1...
June 22, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28640594/biomedical-diagnostics-enabled-by-integrated-organic-and-printed-electronics
#4
Termeh Ahmadraji, Laura Gonzalez-Macia, Tapio Ritvonen, Andreas Willert, Saara Tuurala, Satu Ylimaula, David Donaghy, Mika Suhonen, Dave Smart, Vitaly Efremov, Aoife Morrin, Reinhard R Baumann, Munira Raja, Antti Kemppainen, Anthony J Killard
Organic and printed electronics integration has the potential to revolutionise many technologies, including biomedical diag-nostics. This work demonstrates the successful integration of multiple printed electronic functionalities into a single device capable of the measurement of hydrogen peroxide, and total cholesterol. The single-use device employed printed electrochemical sen-sors for hydrogen peroxide electroreduction integrated with printed electrochromic display and battery. The system was driven by a conventional electronic circuit designed to illustrate the complete integration of silicon ICs via pick and place, or using organic electronic circuits...
June 22, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28637736/transcatheter-closure-mini-invasive-closure-and-open-heart-surgical-repair-for-treatment-of-perimembranous-ventricular-septal-defects-in-children-a-protocol-for-a-network-meta-analysis
#5
Tao You, Kang Yi, Zhao-Hong Ding, Xiao-Dong Hou, Xing-Guang Liu, Xin-Kuan Wang, Long Ge, Jin-Hui Tian
INTRODUCTION: Both transcatheter device closure and surgical repair are effective treatments with excellent midterm outcomes for perimembranous ventricular septal defects (pmVSDs) in children. The mini-invasive periventricular device occlusion technique has become prevalent in research and application, but evidence is limited for the assessment of transcatheter closure, mini-invasive closure and open-heart surgical repair. This study comprehensively compares the efficacy, safety and costs of transcatheter closure, mini-invasive closure and open-heart surgical repair for treatment of pmVSDs in children using Bayesian network meta-analysis...
June 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28636063/solving-interoperability-in-translational-health-perspectives-of-students-from-the-international-partnership-in-health-informatics-education-iphie-2016-master-class
#6
Anne M Turner, Julio C Facelli, Monique Jaspers, Thomas Wetter, Daniel Pfeifer, Laël Cranmer Gatewood, Terry Adam, Yu-Chuan Li, Ming-Chin Lin, R Scott Evans, Anna Beukenhorst, Hugo Johan Theodoore van Mens, Esmee Tensen, Christian Bock, Laura Fendrich, Peter Seitz, Julian Suleder, Ranyah Aldelkhyyel, Kent Bridgeman, Zhen Hu, Aaron Sattler, Shin-Yi Guo, Islam Md Mohaimenul Mohaimenul, Dina Nur Anggraini Ningrum, Hsin-Ru Tung, Jiantano Bian, Joseph M Plasek, Casey Rommel, Juandalyn Burke, Harkirat Sohih
BACKGROUND: In the summer of 2016 an international group of biomedical and health informatics faculty and graduate students gathered for the 16th meeting of the International Partnership in Health Informatics Education (IPHIE) masterclass at the University of Utah campus in Salt Lake City, Utah. This international biomedical and health informatics workshop was created to share knowledge and explore issues in biomedical health informatics (BHI). OBJECTIVE: The goal of this paper is to summarize the discussions of biomedical and health informatics graduate students who were asked to define interoperability, and make critical observations to gather insight on how to improve biomedical education...
June 20, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28633953/reversal-learning-and-resurgence-of-operant-behavior-in-zebrafish-danio-rerio
#7
Toshikazu Kuroda, Yuto Mizutani, Carlos R X Cançado, Christopher A Podlesnik
Zebrafish are used extensively as vertebrate animal models in biomedical research for having such features as a fully sequenced genome and transparent embryo. Yet, operant-conditioning studies with this species are scarce. The present study investigated reversal learning and resurgence of operant behavior in zebrafish. A target response (approaching a sensor) was reinforced in Phase 1. In Phase 2, the target response was extinguished while reinforcing an alternative response (approaching a different sensor)...
June 17, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/28631849/experiences-of-closed-loop-insulin-delivery-among-pregnant-women-with-type-1-diabetes
#8
C Farrington, Z A Stewart, K Barnard, R Hovorka, H R Murphy
AIMS: To explore the experiences of pregnant women with Type 1 diabetes, and the relationships between perceptions of glucose control, attitudes to technology and glycaemic responses with regard to closed-loop insulin delivery. METHODS: We recruited 16 pregnant women with Type 1 diabetes [mean ± sd age 34.1 ± 4.6 years, duration of diabetes 23.6 ± 7.2 years, baseline HbA1c 51±5 mmol/mol (6.8 ± 0.6%)] to a randomized crossover trial of sensor-augmented pump therapy vs automated closed-loop therapy...
June 20, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28631360/reduced-cell-attachment-to-poly-2-hydroxyethyl-methacrylate-coated-ventricular-catheters-in-vitro
#9
Brian W Hanak, Chia-Yun Hsieh, William Donaldson, Samuel R Browd, Kenneth K S Lau, William Shain
The majority of patients with hydrocephalus are dependent on ventriculoperitoneal shunts for diversion of excess cerebrospinal fluid. Unfortunately, these shunts are failure-prone and over half of all life-threatening pediatric failures are caused by obstruction of the ventricular catheter by the brain's resident immune cells, reactive microglia and astrocytes. Poly(2-hydroxyethyl methacrylate) (PHEMA) hydrogels are widely used for biomedical implants. The extreme hydrophilicity of PHEMA confers resistance to protein fouling, making it a strong candidate coating for ventricular catheters...
June 20, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28630345/synthesis-of-asymmetrical-multiantennary-human-milk-oligosaccharides
#10
Anthony R Prudden, Lin Liu, Chantelle J Capicciotti, Margreet A Wolfert, Shuo Wang, Zhongwei Gao, Lu Meng, Kelley W Moremen, Geert-Jan Boons
Despite mammalian glycans typically having highly complex asymmetrical multiantennary architectures, chemical and chemoenzymatic synthesis has almost exclusively focused on the preparation of simpler symmetrical structures. This deficiency hampers investigations into the biology of glycan-binding proteins, which in turn complicates the biomedical use of this class of biomolecules. Herein, we describe an enzymatic strategy, using a limited number of human glycosyltransferases, to access a collection of 60 asymmetric, multiantennary human milk oligosaccharides (HMOs), which were used to develop a glycan microarray...
June 19, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28629096/synthesis-of-magnetic-nanoparticles-and-their-dispersions-with-special-reference-to-applications-in-biomedicine-and-biotechnology
#11
REVIEW
R V Mehta
Biomedical and biotechnological applications of magnetic nanoparticles and their dispersions in liquids are found to be potentially useful. An exponential growth in publications of papers, reviews and patents has been observed. Possibilities of their indiscriminate use on individual as well as environmental health hazards are also investigated. Still, there appears to be a good scope for further research work in the field. Even a small improvement either in preparation method or development of novel nanoparticles may prove to be beneficial in longer run...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28629081/optimized-composition-of-nanocomposite-scaffolds-formed-from-silk-fibroin-and-nano-tio2-for-bone-tissue-engineering
#12
N Johari, H R Madaah Hosseini, A Samadikuchaksaraei
Natural silk fibroin (SF) polymer has biomedical and mechanical properties as a biomaterial for bone tissue engineering scaffolds. Freeze-dried porous nanocomposite scaffolds were prepared from silk fibroin and titanium dioxide (TiO2) nanoparticles as a bioactive reinforcing agent by a phase separation method. In order to fabricate SF/TiO2 scaffolds, 5, 10, 15 and 20wt% of the TiO2 were added to the SF. The phase structure, functional groups and morphology of the scaffolds were evaluated using X-ray diffraction, Fourier transform infrared spectroscopy and scanning electron microscopy techniques, respectively...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28629028/physicochemical-and-biological-assessment-of-peek-composites-embedding-natural-amorphous-silica-fibers-for-biomedical-applications
#13
Patrícia R Monich, Fernanda V Berti, Luismar M Porto, Bruno Henriques, Antonio P Novaes de Oliveira, Márcio C Fredel, Júlio C M Souza
The main aim of this study was to assess the physicochemical and biological properties of a novel poly(ether ether ketone) (PEEK) composite containing 30%wt natural amorphous silica fibers (NASF). PEEK and NASF powders were previously functionalized by atomization and citric acid in order to enhance adhesion between polymeric matrix and fillers. Then, composites were produced by cold compression molding technique at 350°C for 3h. Materials were characterized by chemical, microstructural, thermophysical, mechanical and cytotoxic analysis...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28629005/laser-surface-structuring-of-ti6al4v-substrates-for-adhesion-enhancement-in-ti6al4v-peek-joints
#14
Bruno Henriques, Miguel Sampaio, Mihaela Buciumeanu, Júlio C M Souza, José R Gomes, Filipe Silva, Oscar Carvalho
PEEK is a promising polymer possessing high mechanical strength and biocompatibility and therefore it can be associated to titanium for biomedical applications. This study aimed at producing Ti6Al4V-PEEK joints with enhanced adhesion through laser-structuring Ti6Al4V treatments. Ti6Al4V cylindrical substrates were prepared by two types of surface treatments: alumina blasting and laser structuring. The holes number and size in laser-structured surfaces was varied. PEEK was then hot pressed against the metallic substrate to completely filling the surface cavities...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28628325/tuning-optical-signatures-of-single-and-few-layer-mos2-by-blown-bubble-bulge-straining-up-to-fracture
#15
Rui Yang, Jaesung Lee, Souvik Ghosh, Hao Tang, R Mohan Sankaran, Christian A Zorman, Philip X-L Feng
Emerging atomic layer semiconducting crystals such as molybdenum disulfide (MoS2) are promising candidates for flexible electronics and strain-tunable devices due to their ultrahigh strain limits (up to ~20-30%) and strain-tunable bandgaps. However, high strain levels, controllable isotropic and anisotropic biaxial strains in single- and few-layer MoS2 on device-oriented flexible substrates permitting convenient and fast strain tuning, remain unexplored. Here, we demonstrate a blown-bubble bulge technique for efficiently applying large biaxial strains to atomic layer MoS2 devices on flexible substrate...
June 19, 2017: Nano Letters
https://www.readbyqxmd.com/read/28623971/remodelling-of-the-bovine-placenta-comprehensive-morphological-and-histomorphological-characterization-at-the-late-embryonic-and-early-accelerated-fetal-growth-stages
#16
Consuelo Amor S Estrella, Karen L Kind, Anna Derks, Ruidong Xiang, Nicole Faulkner, Melina Mohrdick, Carolyn Fitzsimmons, Zbigniew Kruk, Frank Grutzner, Claire T Roberts, Stefan Hiendleder
INTRODUCTION: Placental function impacts growth and development with lifelong consequences for performance and health. We provide novel insights into placental development in bovine, an important agricultural species and biomedical model. METHODS: Concepti with defined genetics and sex were recovered from nulliparous dams managed under standardized conditions to study placental gross morphological and histomorphological parameters at the late embryo (Day48) and early accelerated fetal growth (Day153) stages...
July 2017: Placenta
https://www.readbyqxmd.com/read/28620228/a-sensory-material-approach-for-reducing-variability-in-additively-manufactured-metal-parts
#17
B E Franco, J Ma, B Loveall, G A Tapia, K Karayagiz, J Liu, A Elwany, R Arroyave, I Karaman
Despite the recent growth in interest for metal additive manufacturing (AM) in the biomedical and aerospace industries, variability in the performance, composition, and microstructure of AM parts remains a major impediment to its widespread adoption. The underlying physical mechanisms, which cause variability, as well as the scale and nature of variability are not well understood, and current methods are ineffective at capturing these details. Here, a Nickel-Titanium alloy is used as a sensory material in order to quantitatively, and rather rapidly, observe compositional and/or microstructural variability in selective laser melting manufactured parts; thereby providing a means to evaluate the role of process parameters on the variability...
June 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28619614/rapid-ex-vivo-examination-of-mohs-specimens-using-optical-coherence-tomography
#18
D Rashed, D Shah, A Freeman, R J Cook, C Hopper, C M Perrett
BACKGROUND: Mohs micrographic surgery (MMS) is an effective treatment for certain non-melanoma skin cancers. Optical coherence tomography (OCT) is a biomedical imaging modality that permits high-resolution imaging of the epidermis and dermis with the potential to detect both healthy tissue and tumour. OCT may also provide a means of detecting and differentiating between the various histological subtypes of basal cell carcinomas (BCC) in vivo. OBJECTIVE: The aim of this prospective ex vivo study was to evaluate the efficacy of OCT in recognising healthy and pathological margins of excised BCC lesions and detecting different BCC subtypes...
June 12, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28618895/silver-nanoparticles-inhaled-during-pregnancy-reach-and-affect-the-placenta-and-the-foetus
#19
Luisa Campagnolo, Micol Massimiani, Lucia Vecchione, Diletta Piccirilli, Nicola Toschi, Andrea Magrini, Elena Bonanno, Manuel Scimeca, Luca Castagnozzi, Giorgio Buonanno, Luca Stabile, Francesco Cubadda, Federica Aureli, Paul Hb Fokkens, Wolfgang G Kreyling, Flemming R Cassee, Antonio Pietroiusti
Recently, interest for the potential impact of consumer-relevant engineered nanoparticles on pregnancy has dramatically increased. This study investigates whether inhaled silver nanoparticles (AgNPs) reach and cross mouse placental barrier and induce adverse effects. Apart from their relevance for the growing use in consumer products and biomedical applications, AgNPs are selected since they can be unequivocally identified in tissues. Pregnant mouse females are exposed during the first 15 days of gestation by nose-only inhalation to a freshly produced aerosol of 18-20 nm AgNPs for either 1 or 4 hours, at a particle number concentration of 3...
June 16, 2017: Nanotoxicology
https://www.readbyqxmd.com/read/28618356/developmental-neurotoxic-effects-of-graphene-oxide-exposure-in-zebrafish-larvae-danio-rerio
#20
J C Soares, Tcb Pereira, K M Costa, T Maraschin, N R Basso, M R Bogo
Although graphene oxide (GO), a nanomaterial with hexagonal planar layer, has been widely studied due to its applications in neurobiology that include drug delivery and tissue engineering, additional studies to assess its potential toxic effects are still needed. Thus, this study evaluated the effects of GO exposure (at 5, 10, 50 or 100mg/L) during six consecutive days on mortality, hatching, spontaneous movement, heart rate, morphology, locomotion behavior, acetylcholinesterase (AChE) activity, dopamine levels and relative gene expression of developmental neurology-related genes using zebrafish larvae...
June 3, 2017: Colloids and Surfaces. B, Biointerfaces
keyword
keyword
22315
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"