keyword
MENU ▼
Read by QxMD icon Read
search

Microbiome R

keyword
https://www.readbyqxmd.com/read/28925412/prenatal-antimicrobial-use-and-early-childhood-body-mass-index
#1
A E Cassidy-Bushrow, C Burmeister, S Havstad, A M Levin, S V Lynch, D R Ownby, A G Rundle, K J Woodcroft, E M Zoratti, C C Johnson, G Wegienka
BACKGROUND/OBJECTIVES: Growing evidence suggests that antibiotic use is associated with childhood body mass index (BMI), potentially via mechanisms mediated by gut microbiome alterations. Less is known on the potential role of prenatal antimicrobial use in offspring obesity risk. We examined whether prenatal antibiotic or antifungal use was associated with BMI at the age of 2 years in 527 birth cohort participants. METHODS/SUBJECTS: Antimicrobial use was obtained from the prenatal medical record...
August 17, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28924190/microbiome-of-pacific-whiteleg-shrimp-reveals-differential-bacterial-community-composition-between-wild-aquacultured-and-ahpnd-ems-outbreak-conditions
#2
Fernanda Cornejo-Granados, Alonso A Lopez-Zavala, Luigui Gallardo-Becerra, Alfredo Mendoza-Vargas, Filiberto Sánchez, Rodrigo Vichido, Luis G Brieba, Maria Teresa Viana, Rogerio R Sotelo-Mundo, Adrián Ochoa-Leyva
Crustaceans form the second largest subphylum on Earth, which includes Litopeneaus vannamei (Pacific whiteleg shrimp), one of the most cultured shrimp worldwide. Despite efforts to study the shrimp microbiota, little is known about it from shrimp obtained from the open sea and the role that aquaculture plays in microbiota remodeling. Here, the microbiota from the hepatopancreas and intestine of wild type (wt) and aquacultured whiteleg shrimp and pond sediment from hatcheries were characterized using sequencing of seven hypervariable regions of the 16S rRNA gene...
September 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28924143/fructooligosaccharide-fos-and-galactooligosaccharide-gos-increase-bifidobacterium-but-reduce-butyrate-producing-bacteria-with-adverse-glycemic-metabolism-in-healthy-young-population
#3
Feitong Liu, Pan Li, Muxuan Chen, Yuemei Luo, M Prabhakar, Huimin Zheng, Yan He, Qi Qi, Haoyu Long, Yi Zhang, Huafang Sheng, Hongwei Zhou
The gut microbiota has been implicated in glucose intolerance and its progression towards type-2 diabetes mellitus (T2DM). Relevant randomized clinical trial with prebiotic intervention was inadequate. We sought to evaluate the impact of fructooligosaccharides (FOS) and galactooligosaccharides (GOS) on glycemia during oral glucose tolerance test (OGTT) and intestinal microbiota. A randomized double-blind cross-over study was performed with 35 adults treated with FOS and GOS for 14 days (16 g/day). Faeces sampling, OGTT and anthropometric parameters were performed...
September 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28919884/secretome-of-intestinal-bacilli-a-natural-guard-against-pathologies
#4
REVIEW
Olga N Ilinskaya, Vera V Ulyanova, Dina R Yarullina, Ilgiz G Gataullin
Current studies of human gut microbiome usually do not consider the special functional role of transient microbiota, although some of its members remain in the host for a long time and produce broad spectrum of biologically active substances. Getting into the gastrointestinal tract (GIT) with food, water and probiotic preparations, two representatives of Bacilli class, genera Bacillus and Lactobacillus, colonize epithelium blurring the boundaries between resident and transient microbiota. Despite their minor proportion in the microbiome composition, these bacteria can significantly affect both the intestinal microbiota and the entire body thanks to a wide range of secreted compounds...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28919882/effects-of-soil-pre-treatment-with-basamid%C3%A2-granules-brassica-juncea-raphanus-sativus-and-tagetes-patula-on-bacterial-and-fungal-communities-at-two-apple-replant-disease-sites
#5
Bunlong Yim, Heike Nitt, Andreas Wrede, Samuel Jacquiod, Søren J Sørensen, Traud Winkelmann, Kornelia Smalla
Nurseries producing apple and rose rootstock plants, apple orchards as well as rose production often experience replanting problems after several cultivations at the same site when a chemical soil disinfectant is not applied. The etiology of apple and rose replanting problems is most likely caused by soil-borne pathogen complex, defined as "replant disease (RD)". Symptoms typical of RD are reduced shoot and root growth, a smaller leaf area, a significant decrease in plant biomass, yield and fruit quality and a shorter life span...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28910628/tooth-be-told-genetics-influences-oral-microbiome
#6
Emily R Davenport
The mix of bacteria that coat our teeth impact oral health, but it remains unclear what factors govern their composition. In this issue of Cell Host & Microbe, Gomez et al. (2017) examine the relationship between host genetics and the oral microbiome in the context of health and disease.
September 13, 2017: Cell Host & Microbe
https://www.readbyqxmd.com/read/28904640/short-term-dietary-methionine-supplementation-affects-one-carbon-metabolism-and-dna-methylation-in-the-mouse-gut-and-leads-to-altered-microbiome-profiles-barrier-function-gene-expression-and-histomorphology
#7
Isabelle R Miousse, Rupak Pathak, Sarita Garg, Charles M Skinner, Stepan Melnyk, Oleksandra Pavliv, Howard Hendrickson, Reid D Landes, Annie Lumen, Alan J Tackett, Nicolaas E P Deutz, Martin Hauer-Jensen, Igor Koturbash
BACKGROUND: Methionine, a central molecule in one-carbon metabolism, is an essential amino acid required for normal growth and development. Despite its importance to biological systems, methionine is toxic when administered at supra-physiological levels. The aim of this study was to investigate the effects of short-term methionine dietary modulation on the proximal jejunum, the section of the gut specifically responsible for amino acid absorption, in a mouse model. Eight-week-old CBA/J male mice were fed methionine-adequate (MAD; 6...
2017: Genes & Nutrition
https://www.readbyqxmd.com/read/28904056/simultaneously-monitoring-immune-response-and-microbial-infections-during-pregnancy-through-plasma-cfrna-sequencing
#8
Wenying Pan, Thuy T M Ngo, Joan Camunas-Soler, Chun-Xiao Song, Mark Kowarsky, Yair J Blumenfeld, Ronald J Wong, Gary M Shaw, David K Stevenson, Stephen R Quake
BACKGROUND: Plasma cell-free RNA (cfRNA) encompasses a broad spectrum of RNA species that can be derived from both human cells and microbes. Because cfRNA is fragmented and of low concentration, it has been challenging to profile its transcriptome using standard RNA-seq methods. METHODS: We assessed several recently developed RNA-seq methods on cfRNA samples. We then analyzed the dynamic changes of both the human transcriptome and the microbiome of plasma during pregnancy from 60 women...
September 13, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28900019/the-human-salivary-microbiome-is-shaped-by-shared-environment-rather-than-genetics-evidence-from-a-large-family-of-closely-related-individuals
#9
Liam Shaw, Andre L R Ribeiro, Adam P Levine, Nikolas Pontikos, Francois Balloux, Anthony W Segal, Adam P Roberts, Andrew M Smith
The human microbiome is affected by multiple factors, including the environment and host genetics. In this study, we analyzed the salivary microbiomes of an extended family of Ashkenazi Jewish individuals living in several cities and investigated associations with both shared household and host genetic similarities. We found that environmental effects dominated over genetic effects. While there was weak evidence of geographical structuring at the level of cities, we observed a large and significant effect of shared household on microbiome composition, supporting the role of the immediate shared environment in dictating the presence or absence of taxa...
September 12, 2017: MBio
https://www.readbyqxmd.com/read/28894161/microbial-communities-in-placentas-from-term-normal-pregnancy-exhibit-spatially-variable-profiles
#10
Lindsay A Parnell, Catherine M Briggs, Bin Cao, Omar Delannoy-Bruno, Andrew E Schrieffer, Indira U Mysorekar
The placenta is the principal organ nurturing the fetus during pregnancy and was traditionally considered to be sterile. Recent work has suggested that the placenta harbours microbial communities, however the location and possible function of these microbes remain to be confirmed and elucidated. Here, we employed genomic DNA sequencing of multiple variable (V) regions of the bacterial 16S ribosomal gene, to interrogate microbial profiles in term pregnancies, from the basal plate, which is in direct contact with maternal uterine, endothelial, and immune cells; placental villi, which are bathed in maternal blood, and fetal membranes, which encapsulate the amniotic cavity...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28888639/increased-microbiome-diversity-at-the-time-of-infection-is-associated-with-improved-growth-rates-of-pigs-after-co-infection-with-porcine-reproductive-and-respiratory-syndrome-virus-prrsv-and-porcine-circovirus-type-2-pcv2
#11
Rebecca A Ober, James B Thissen, Crystal J Jaing, Ada G Cino-Ozuna, Raymond R R Rowland, Megan C Niederwerder
Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2) are two of the most important pathogens affecting the swine industry worldwide. Co-infections are common on a global scale, resulting in pork production losses through reducing weight gain and causing respiratory disease in growing pigs. Our initial work demonstrated that the fecal microbiome was associated with clinical outcome of pigs 70days post-infection (dpi) with PRRSV and PCV2. However, it remained uncertain if microbiome characteristics could predispose response to viral infection...
September 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28887570/the-salivary-microbiome-is-consistent-between-subjects-and-resistant-to-impacts-of-short-term-hospitalization
#12
Damien J Cabral, Jenna I Wurster, Myrto E Flokas, Michail Alevizakos, Michelle Zabat, Benjamin J Korry, Aislinn D Rowan, William H Sano, Nikolaos Andreatos, R Bobby Ducharme, Philip A Chan, Eleftherios Mylonakis, Beth Burgwyn Fuchs, Peter Belenky
In recent years, a growing amount of research has begun to focus on the oral microbiome due to its links with health and systemic disease. The oral microbiome has numerous advantages that make it particularly useful for clinical studies, including non-invasive collection, temporal stability, and lower complexity relative to other niches, such as the gut. Despite recent discoveries made in this area, it is unknown how the oral microbiome responds to short-term hospitalization. Previous studies have demonstrated that the gut microbiome is extremely sensitive to short-term hospitalization and that these changes are associated with significant morbidity and mortality...
September 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28886168/unraveling-the-human-salivary-microbiome-diversity-in-indian-populations
#13
Anujit Sarkar, Mark Stoneking, Madhusudan R Nandineni
The importance of studying the salivary microbiome has been highlighted for its connection to health and disease and as a potential tool for supplementing human genetic diversity studies. While the salivary microbiome has been studied in various world populations, Indian populations have not been examined. We therefore analyzed microbiome diversity in saliva samples from 92 volunteers from eight different sampling locations in India by amplifying and sequencing variable regions (V1 and V2) of the bacterial 16S rRNA gene...
2017: PloS One
https://www.readbyqxmd.com/read/28875948/the-tongue-microbiome-in-healthy-subjects-and-patients-with-intra-oral-halitosis
#14
Kavitha Seerangaiyan, Arie Jan van Winkelhoff, Hermie J M Harmsen, John W A Rossen, Edwin G Winkel
Intra-oral halitosis (IOH) is an unpleasant odor emanating from the oral cavity. It is thought that the microbiota of the dorsal tongue coating plays a crucial role in this condition. The aim of the study was to investigate the composition of the tongue microbiome in subjects with and without IOH. A total of 26 subjects, 16 IOH patients and 10 healthy subjects were recruited based on their organoleptic score and volatile sulfur compound (VSC) measurements. The composition of the tongue microbiome was studied using the 16s amplicon sequencing of the V3-V4 hyper variable region with an Illumina MiSeq...
September 6, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28874832/antibiotic-induced-perturbations-in-microbial-diversity-during-post-natal-development-alters-amyloid-pathology-in-an-aged-appswe-ps1%C3%AE-e9-murine-model-of-alzheimer-s-disease
#15
Myles R Minter, Reinhard Hinterleitner, Marlies Meisel, Can Zhang, Vanessa Leone, Xiaoqiong Zhang, Paul Oyler-Castrillo, Xulun Zhang, Mark W Musch, Xunuo Shen, Bana Jabri, Eugene B Chang, Rudolph E Tanzi, Sangram S Sisodia
Recent evidence suggests the commensal microbiome regulates host immunity and influences brain function; findings that have ramifications for neurodegenerative diseases. In the context of Alzheimer's disease (AD), we previously reported that perturbations in microbial diversity induced by life-long combinatorial antibiotic (ABX) selection pressure in the APPSWE/PS1ΔE9 mouse model of amyloidosis is commensurate with reductions in amyloid-β (Aβ) plaque pathology and plaque-localised gliosis. Considering microbiota-host interactions, specifically during early post-natal development, are critical for immune- and neuro-development we now examine the impact of microbial community perturbations induced by acute ABX exposure exclusively during this period in APPSWE/PS1ΔE9 mice...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28874767/a-cross-sectional-comparative-study-of-gut-bacterial-community-of-indian-and-finnish-children
#16
Shreyas V Kumbhare, Himanshu Kumar, Somak P Chowdhury, Dhiraj P Dhotre, Akihito Endo, Jaana Mättö, Arthur C Ouwehand, Samuli Rautava, Ruchi Joshi, Nitinkumar P Patil, Ravindra H Patil, Erika Isolauri, Ashish R Bavdekar, Seppo Salminen, Yogesh S Shouche
The human gut microbiome plays a crucial role in the compositional development of gut microbiota. Though well documented in western pediatrics population, little is known about how various host conditions affect populations in different geographic locations such as the Indian subcontinent. Given the impact of distinct environmental conditions, our study assess the gut bacterial diversity of a small cohort of Indian and Finnish children and investigated the influence of FUT2 secretor status and birth mode on the gut microbiome of these populations...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28872698/a-multivariate-distance-based-analytic-framework-for-microbial-interdependence-association-test-in-longitudinal-study
#17
Yilong Zhang, Sung Won Han, Laura M Cox, Huilin Li
Human microbiome is the collection of microbes living in and on the various parts of our body. The microbes living on our body in nature do not live alone. They act as integrated microbial community with massive competing and cooperating and contribute to our human health in a very important way. Most current analyses focus on examining microbial differences at a single time point, which do not adequately capture the dynamic nature of the microbiome data. With the advent of high-throughput sequencing and analytical tools, we are able to probe the interdependent relationship among microbial species through longitudinal study...
September 5, 2017: Genetic Epidemiology
https://www.readbyqxmd.com/read/28869358/the-role-of-respiratory-tract-infections-and-the-microbiome-in-the-development-of-asthma-a-narrative-review
#18
REVIEW
Evelien R van Meel, Vincent W V Jaddoe, Klaus Bønnelykke, Johan C de Jongste, Liesbeth Duijts
Asthma is a common disease in childhood, and might predispose for chronic obstructive respiratory morbidity in adolescence and adulthood. Various early-life risk factors might influence the risk of wheezing, asthma, and lower lung function in childhood. Cohort studies demonstrated that lower respiratory tract infections in the first years of life are associated with an increased risk of wheezing and asthma, while the association with lung function is less clear. Additionally, the gut and airway microbiome might influence the risk of wheezing and asthma...
September 4, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28868052/high-resolution-microbiome-profiling-for-detection-and-tracking-of-salmonella-enterica
#19
Christopher J Grim, Ninalynn Daquigan, Tina S Lusk Pfefer, Andrea R Ottesen, James R White, Karen G Jarvis
16S rRNA community profiling continues to be a useful tool to study microbiome composition and dynamics, in part due to advances in next generation sequencing technology that translate into reductions in cost. Reliable taxonomic identification to the species-level, however, remains difficult, especially for short-read sequencing platforms, due to incomplete coverage of the 16S rRNA gene. This is especially true for Salmonella enterica, which is often found as a low abundant member of the microbial community, and is often found in combination with several other closely related enteric species...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28864748/novel-interactions-between-gut-microbiome-and-host-drug-processing-genes-modify-the-hepatic-metabolism-of-the-environmental-chemicals-pbdes
#20
Cindy Yanfei Li, Soowan Lee, Sara Cade, Li-Jung Kuo, Irvin R Schultz, Deepak K Bhatt, Bhagwat Prasad, Theo K Bammler, Julia Yue Cui
The gut microbiome is a novel frontier in xenobiotic metabolism. Polybrominated diphenyl ethers (PBDEs), especially BDE-47 and BDE-99, are among the most abundant and persistent environmental contaminants that produce a variety of toxicities. Little is known about how the gut microbiome affects the hepatic metabolism of PBDEs and the PBDE-mediated regulation of drug-processing genes (DPGs) in vivo. The goal of this study was to determine the role of gut microbiome in modulating the hepatic biotransformation of PBDEs...
September 1, 2017: Drug Metabolism and Disposition: the Biological Fate of Chemicals
keyword
keyword
22313
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"