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https://www.readbyqxmd.com/read/27909413/sex-effects-on-smoking-cue-perception-in-non-smokers-smokers-and-ex-smokers-a-pilot-study
#1
Davide Zanchi, Arthur Brody, Stefan Borgwardt, Sven Haller
INTRODUCTION: Recent neuroimaging research suggests sex-related brain differences in smoking addiction. In the present pilot study, we assessed gender-related differences in brain activation in response to cigarette-related video cues, investigating non-smokers, smokers, and ex-smokers. METHODS: First, we compared 29 females (28.6 ± 5.3) vs. 23 males (31.5 ± 6.4), regardless of current smoking status to assess global gender-related effects. Second, we performed a post hoc analysis of non-smokers (9 females and 8 males), smokers (10 females and 8 males), and ex-smokers (10 females and 7 males)...
2016: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/27898683/mortality-in-hiv-infected-alcohol-and-drug-users-in-st-petersburg-russia
#2
Nadia S Fairbairn, Alexander Y Walley, Debbie M Cheng, Emily Quinn, Carly Bridden, Christine Chaisson, Elena Blokhina, Dmitry Lioznov, Evgeny Krupitsky, Anita Raj, Jeffrey H Samet
In Russia, up to half of premature deaths are attributed to hazardous drinking. The respective roles of alcohol and drug use in premature death among people with HIV in Russia have not been described. Criminalization and stigmatization of substance use in Russia may also contribute to mortality. We explored whether alcohol, drug use and risk environment factors are associated with short-term mortality in HIV-infected Russians who use substances. Secondary analyses were conducted using prospective data collected at baseline, 6 and 12-months from HIV-infected people who use substances recruited between 2007-2010 from addiction and HIV care settings in a single urban setting of St...
2016: PloS One
https://www.readbyqxmd.com/read/27896481/high-perineal-and-overall-frequency-of-staphylococcus-aureus-in-people-who-inject-drugs-compared-to-non-injectors
#3
Disa Dahlman, Farnaz Jalalvand, Marianne Alanko Blomé, Anders Håkansson, Håkan Janson, Susanne Quick, Anna C Nilsson
To investigate the prevalence, distribution, and colonization burden of Staphylococcus aureus (S. aureus) and MRSA in different body sites among people who inject drugs (PWID) and compare it to a control group consisting of non-injectors. In this cross-sectional survey, 49 active PWID from the needle exchange program (NEP) in Malmö, Sweden, and 60 non-injecting controls from an emergency psychiatric inpatient ward at Malmö Addiction Centre were tested for S. aureus (including MRSA) by culture, PCR, and MALDI-TOF...
November 28, 2016: Current Microbiology
https://www.readbyqxmd.com/read/27872524/human-papilloma-virus-in-oral-cavity-cancer-and-relation-to-change-in-quality-of-life-following-treatment-a-pilot-study-from-northern-india
#4
Abhishek Kumar Singh, Jitendra Kumar Kushwaha, Akshay Anand, Abhinav Arun Sonkar, Nuzhat Husain, Kirti Srivastava, Sudhir Singh
Human papilloma virus (HPV)-associated head and neck cancer (HNC) has generated significant amount of research interest in recent times with focus shifted to oral cavity squamous cell cancer (OCSCC) after oropharyngeal cancer. Due to high incidence of OCSCC and anecdotal reports on association of HPV infection from northern region of India, this study was conceived to investigate HPV infection and establish its association with lifestyle habits such as tobacco, alcohol consumption, oro-genital sex, number of sexual contacts, and change in quality of life posttreatment...
December 2016: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27870459/sex-differences-in-nicotine-preference
#5
REVIEW
Sakire Pogun, Gorkem Yararbas, Tanseli Nesil, Lutfiye Kanit
Smoking is the major cause of preventable deaths worldwide, and although there is a decline in overall smoking prevalence in developed countries, the decline in women is less pronounced than in men. Women become dependent faster and experience greater difficulties in quitting. Similar trends have been observed in animal models of nicotine/tobacco addiction. Individual differences in vulnerability to drug abuse are also observed in nicotine/tobacco addiction and point to the importance of sex differences. This Review, summarizes findings from three experimental approaches used to depict nicotine preference in animal models, intravenous and oral nicotine self-administration and nicotine-induced conditioned place preference...
January 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27870394/sex-differences-gender-and-addiction
#6
REVIEW
Jill B Becker, Michele L McClellan, Beth Glover Reed
This review discusses alcohol and other forms of drug addiction as both a sociocultural and biological phenomenon. Sex differences and gender are not solely determined by biology, nor are they entirely sociocultural. The interactions among biological, environmental, sociocultural, and developmental influences result in phenotypes that may be more masculine or more feminine. These gender-related sex differences in the brain can influence the responses to drugs of abuse, progressive changes in the brain after exposure to drugs of abuse and whether addiction results from drug-taking experiences...
January 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27857051/elevation-of-the-acth-cortisol-ratio-in-female-opioid-dependent-patients-a-biomarker-of-aging-and-correlate-of-metabolic-and-immune-activation
#7
(no author information available yet)
BACKGROUND: Whilst the hypothalamic-pituitary-adrenal (HPA) Axis is a major stress axis, and is necessarily perturbed in opioid dependency, and stress is a major contributor to aging mechanisms, the HPA axis has not been studied in opioid dependency in an age-dependent manner. OBJECTIVE: Hypothesis - Differences in age dependent levels of HPA components. DESIGN: Cross-sectional comparison of general medical and opioid dependent patients (ODP, GMP)...
September 18, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/27855664/challenges-in-detecting-and-diagnosing-substance-use-in-women-in-the-acute-psychiatric-department-a-naturalistic-cohort-study
#8
Torill Vassli Sallaup, Arne Einar Vaaler, Valentina Cabral Iversen, Ismail Cuneyt Guzey
BACKGROUND: This study examines sex differences in substance use and substance use disorder in the acute psychiatric department, and possible interactions between sex and clinical and social factors associated with this phenomenon. METHODS: Data concerning substance use were collected in a naturalistic cohort study (n = 384, 51.6% male, 48.4% female) in an acute psychiatric department. Recent intake of substances at admission, diagnosis of substance use disorder and demographic and socioeconomic information were recorded...
November 17, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27837404/the-biology-of-addiction
#9
Brent MacNicol
In this narrative review, the neurobiological mechanisms underlying substance abuse and addiction are discussed with a particular emphasis on the mechanisms that promote ongoing use and relapse. Addiction is estimated to affect 10-15% or more of the adult population, including physicians. Genetic predisposition, psychological and environmental risk factors, the timing of exposure to the substance, the type of substance used, and the frequency of use influence the individual's susceptibility to addiction. Abused substances act on the brain's reward system, a neural circuit that produces pleasurable feelings in response to stimuli that promote survival, thereby modifying future behavior to seek out similar stimuli...
November 11, 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/27833864/a-clinical-study-of-oral-mucosal-lesions-in-patients-visiting-a-tertiary-care-centre-in-central-india
#10
Rashmi Goyal, Shalini Jadia, Leena Jain, Chhavi Agarawal
The aim of this study was to find the frequency of various oral mucosal lesions in relation to age, sex, site and associated addiction habits. This retrospective study was done in tertiary care centre including 1280 patients of oral mucosal lesions. Clinical findings and detailed history of their addiction habits with frequency and duration was noted from the existing data. Cytological and histopathological diagnosis of various lesions was recorded to conclude diagnosis. The most common lesion in this study was found to be aphthous ulcers (44...
December 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/27829288/co-occurring-substance-related-and-behavioral-addiction-problems-a-person-centered-lay-epidemiology-approach
#11
Barna Konkolÿ Thege, David C Hodgins, T Cameron Wild
Background and aims The aims of this study were (a) to describe the prevalence of single versus multiple addiction problems in a large representative sample and (b) to identify distinct subgroups of people experiencing substance-related and behavioral addiction problems. Methods A random sample of 6,000 respondents from Alberta, Canada, completed survey items assessing self-attributed problems experienced in the past year with four substances (alcohol, tobacco, marijuana, and cocaine) and six behaviors (gambling, eating, shopping, sex, video gaming, and work)...
November 10, 2016: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/27822027/childhood-maltreatment-as-a-risk-factor-for-copd-findings-from-a-population-based-survey-of-canadian-adults
#12
Margot E Shields, Wendy E Hovdestad, Charles P Gilbert, Lil E Tonmyr
OBJECTIVE: The aim of this study was to examine the associations between childhood maltreatment (CM) and COPD in adulthood. METHODS: Data were from 15,902 respondents to the 2012 Canadian Community Health Survey - Mental Health. Multiple logistic regression models were used to examine associations between CM and COPD and the role of smoking and mental and substance use variables as mediators in associations. RESULTS: COPD in adulthood was related to CM, with associations differing by sex...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27821595/cannabis-exposure-as-an-interactive-cardiovascular-risk-factor-and-accelerant-of-organismal-ageing-a-longitudinal-study
#13
Albert Stuart Reece, Amanda Norman, Gary Kenneth Hulse
OBJECTIVES: Many reports exist of the cardiovascular toxicity of smoked cannabis but none of arterial stiffness measures or vascular age (VA). In view of its diverse toxicology, the possibility that cannabis-exposed patients may be ageing more quickly requires investigation. DESIGN: Cross-sectional and longitudinal, observational. Prospective. SETTING: Single primary care addiction clinic in Brisbane, Australia. PARTICIPANTS: 11 cannabis-only smokers, 504 tobacco-only smokers, 114 tobacco and cannabis smokers and 534 non-smokers...
November 7, 2016: BMJ Open
https://www.readbyqxmd.com/read/27810653/cortical-excitability-in-tramadol-dependent-patients-a-transcranial-magnetic-stimulation-study
#14
Eman M Khedr, Romany H Gabra, Mostafa Noaman, Noha Abo Elfetoh, Hanan S M Farghaly
BACKGROUND: Addiction to tramadol, a widely used analgesic, is becoming increasingly common. Tramadol can also induce seizures even after a single clinical dose. We tested whether the epileptogenicity of tramadol was associated with any changes in cortical excitability and inhibitory transmission using transcranial magnetic stimulation (TMS). METHODS: The study included 16 tramadol dependent patients and 15 age and sex matched healthy volunteers. Clinical evaluation was conducted using an addiction severity index...
October 17, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/27806533/epidemiologic-correlates-of-chronic-respiratory-infections-in-adults-an-urban-slum-of-bhubaneswar-odisha-india
#15
Sonali Kar, Ipsa Mohapatra, Amrita Konar
INTRODUCTION: Urbanization is marked by emergence of slum areas, wherein migrants from the nearby villages stay in temporary establishments for seeking avenues of employment. These dwellings lack most of the essential living conditions like safe water, healthy living conditions and access to health services. This population is also vulnerable to social evils like alcohol and tobacco addiction. KIMS, a medical college in Bhubaneswar, Odisha, India has an Urban Health Training Centre (UHTC) that caters to a slum population of nearly 12,000 population for their primary health needs...
August 4, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27803891/a-qualitative-study-of-the-relationship-between-methamphetamine-abuse-and-sexual-dysfunction-in-male-substance-abusers
#16
Behrouz Dolatshahi, Ali Farhoudian, Mozhgan Falahatdoost, Mahmoud Tavakoli, Ebrahim Rezaie Dogahe
BACKGROUND: Increased prevalent use of methamphetamine is a global public challenge. Information on drug use can be helpful in preventing high-risk behavior related to drug abuse. OBJECTIVES: This study aims to investigate the sexual function changes related to methamphetamine use in the male clients of public and private addiction treatment centers. PATIENTS AND METHODS: In this qualitative study, 45 men (35 methamphetamine users, 5 family members of the users, and 5 psychiatrists or physicians who were famous for treating or researching addiction) are involved...
September 2016: International Journal of High Risk Behaviors & Addiction
https://www.readbyqxmd.com/read/27784181/barriers-to-female-sex-addiction-treatment-in-the-uk
#17
Manpreet K Dhuffar, Mark D Griffiths
Background Over the last 20 years, behavioral addictions (e.g., addictions to gambling, playing video games, work, etc.) have become more accepted among both public and scientific communities. Addiction to sex is arguably a more controversial issue, but this does not take away from the fact that some individuals seek professional help for problematic excessive sex, irrespective of how the behavior is conceptualized. Empirical evidence suggests that among treatment seekers, men are more likely than women to seek help for sex addiction (SA)...
October 27, 2016: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/27780613/multiple-sclerosis-and-alcohol-use-disorders-in-hospital-mortality-extended-hospital-stays-and-overexpenditures
#18
M Gili-Miner, J López-Méndez, A Vilches-Arenas, G Ramírez-Ramírez, D Franco-Fernández, J Sala-Turrens, L Béjar-Prado
INTRODUCTION: The objective of this study was to analyse the impact of alcohol use disorders (AUD) in patients with multiple sclerosis (MS) in terms of in-hospital mortality, extended hospital stays, and overexpenditures. METHODS: We conducted a retrospective observational study in a sample of MS patients obtained from minimal basic data sets from 87 Spanish hospitals recorded between 2008 and 2010. Mortality, length of hospital stays, and overexpenditures attributable to AUD were calculated...
October 22, 2016: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/27776797/-patterns-of-prescription-of-opioid-analgesics-in-h%C3%A3-tel-dieu-de-france-of-beyrouth
#19
P Noufi, E Khoury, E Ayoub, N Naccache, S Richa
OBJECTIVES: Use of chronic opioid therapy has increased substantially over the past few years, even though opioid therapy is associated with potentially serious harms, including opioid-related adverse effects and outcomes. Prescription of opioids for chronic pain, particularly nonmalignant chronic pain, remains controversial. In the midst of this controversy, patterns of actual prescription and influences on these patterns are not well understood. This study aims to describe the frequency of prescription of opioid analgesics in a university hospital, the attitudes of doctors towards this category of drugs, and the follow-up modalities of patients taking these drugs...
October 21, 2016: L'Encéphale
https://www.readbyqxmd.com/read/27765626/the-effect-of-sazetidine-a-and-other-nicotinic-ligands-on-nicotine-controlled-goal-tracking-in-female-and-male-rats
#20
S Charntikov, A M Falco, K Fink, L P Dwoskin, R A Bevins
Nicotine is the primary addictive component of tobacco products and its complex stimulus effects are readily discriminated by human and non-human animals. Previous research with rodents directly investigating the nature of the nicotine stimulus has been limited to males. The current study began to address this significant gap in the literature by training female and male rats to discriminate 0.4 mg/kg nicotine from saline in the discriminated goal-tracking task. In this task, access to sucrose was intermittently available on nicotine session...
October 17, 2016: Neuropharmacology
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