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https://www.readbyqxmd.com/read/29450245/video-game-addiction-and-psychological-distress-among-expatriate-adolescents-in-saudi-arabia
#1
Nazmus Saquib, Juliann Saquib, AbdulWaris Wahid, Abdulrahman Akmal Ahmed, Hamad Emad Dhuhayr, Mohamed Saddik Zaghloul, Mohammed Ewid, Abdulrahman Al-Mazrou
Introduction: Few studies have estimated screen time among Arab adolescents, and no studies, to date, have published data on addiction to video games or Internet games among Arab adolescents. This study aimed to assess the prevalence of addiction to video games and its correlation with mental health in a sample of expatriate high school students from the Al-Qassim region of Saudi Arabia. Methods: The survey was conducted in 2016 among 276 students enrolled in ninth through twelfth grades in the International Schools in Buraidah, Al-Qassim...
December 2017: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29445298/presence-of-pain-on-three-or-more-days-of-the-week-is-associated-with-worse-patient-reported-outcomes-in-adults-with-sickle-cell-disease
#2
Nitya Bakshi, Diana Ross, Lakshmanan Krishnamurti
While acute episodic pain is the hallmark of sickle cell disease (SCD), transition to chronic pain is a major cause of morbidity and impaired quality of life. One of the core diagnostic criteria used by Analgesic, Anesthetic, and Addiction Clinical Trial Translations Innovations Opportunities and Networks-American Pain Society Pain Taxonomy (AAPT) to define chronic SCD pain is the presence of pain on a "majority of days" in the past 6 months in one or more locations. The frequency characteristic of "majority of days" is adapted from the criteria of 15 days or more per month, used to define chronic migraine, but there are inadequate data to support this cutoff in SCD...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29434815/dopamine-receptor-d4-promoter-hypermethylation-increases-the-risk-of-drug-addiction
#3
Huihui Ji, Xuting Xu, Guili Liu, Huifen Liu, Qinwen Wang, Wenwen Shen, Longhui Li, Xiaohu Xie, Haochang Hu, Lei Xu, Wenhua Zhou, Shiwei Duan
Heroin and methylamphetamine (METH) are two addictive drugs that cause serious problems for society. Dopamine receptor D4 (DRD4), a key receptor in the dopaminergic system, may facilitate the development of drug addiction. The aim of the present study was to investigate the association between the promoter methylation level of DRD4 gene and drug addiction. Bisulfite pyrosequencing technology was used to measure the methylation levels of DRD4 promoter in 60 drug addicts and 52 matched controls. Significantly higher levels of DRD4 CpG1 and CpG4 methylation were detected in METH and heroin drug addicts compared with controls (P<0...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29433454/hepatitis-b-c-in-the-countries-of-the-eu-eea-a-systematic-review-of-the-prevalence-among-at-risk-groups
#4
Abby May Falla, Sanne Henrietta Ina Hofstraat, Erika Duffell, Susan Josien Maria Hahné, Lara Tavoschi, Irene Karen Veldhuijzen
BACKGROUND: In 2016, the World Health Organisation set a goal to eliminate viral hepatitis by 2030. Robust epidemiological information underpins all efforts to achieve elimination and this systematic review provides estimates of HBsAg and anti-HCV prevalence in the European Union/European Economic Area (EU/EEA) among three at-risk populations: people in prison, men who have sex with men (MSM), and people who inject drugs (PWID). METHODS: Estimates of the prevalence among the three risk groups included in our study were derived from multiple sources...
February 12, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29417149/association-of-dsm-5-betel-quid-use-disorder-with-oral-potentially-malignant-disorder-in-6-betel-quid-endemic-asian-populations
#5
Chien-Hung Lee, Albert Min-Shan Ko, Frances M Yang, Chung-Chieh Hung, Saman Warnakulasuriya, Salah Osman Ibrahim, Rosnah Binti Zain, Ying-Chin Ko
Importance: Betel-quid (BQ) is the fourth most popular psychoactive agent worldwide. An emerging trend across Asia is the addictive consumption of BQ, which is associated with oral cancer and other health consequences. Objective: To investigate the validity and pattern of DSM-5-defined BQ use disorder (BUD) and its association with oral potentially malignant disorder (OPMD) among Asian populations. Design, Setting, and Participants: In-person interviews were conducted from January 1, 2009, to February 28, 2010, among a random sample of 8922 noninstitutionalized adults from the Asian Betel-quid Consortium study, an Asian representative survey of 6 BQ-endemic populations...
February 7, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29396749/neuroticism-magnifies-the-detrimental-association-between-social-media-addiction-symptoms-and-wellbeing-in-women-but-not-in-men-a-three-way-moderation-model
#6
Ofir Turel, Natalie Tasha Poppa, Oren Gil-Or
Addiction symptoms in relation to the use of social networking sites (SNS) can be associated with reduced wellbeing. However, the mechanisms that can control this association have not been fully characterized, despite their relevance to effective treatment of individuals presenting SNS addiction symptoms. In this study we hypothesize that sex and neuroticism, which are important determinants of how people evaluate and respond to addiction symptoms, moderate this association. To examine these assertions, we employed hierarchical linear and logistic regression techniques to analyze data collected with a cross-sectional survey of 215 Israeli college students who use SNS...
February 3, 2018: Psychiatric Quarterly
https://www.readbyqxmd.com/read/29382494/-clinical-epidemiological-study-in-children-with-cleft-lip-palate-in-a-secondary-level-hospital
#7
Alicia Pons-Bonals, Leticia Pons-Bonals, Sandra Margarita Hidalgo-Martínez, Carlos Francisco Sosa-Ferreyra
BACKGROUND: One of the most common congenital disorders that affects the facial structures is the cleft lip palate (CLP). The aim of this study was to generate the clinical-epidemiological profile of CLP patients from Hospital de Especialidades del Niño y la Mujer (HENM) Dr. Felipe Nuñez Lara, from the Ministry of Health, Queretaro, Mexico, from 2011 to 2014, who received treatment from the Cleft Lip Palate Clinic in order to provide interdisciplinary treatments for CLP patients based on the information from the pediatric records...
March 2017: Boletín Médico del Hospital Infantil de México
https://www.readbyqxmd.com/read/29369159/substance-associated-elevations-in-monocyte-activation-among-methamphetamine-users-with-treated-hiv-infection
#8
Adam W Carrico, Emily M Cherenack, Margaret E Roach, Elise D Riley, Olorunleke Oni, Samantha E Dilworth, Steven Shoptaw, Peter Hunt, Sabita Roy, Suresh Pallikkuth, Savita Pahwa
OBJECTIVE: Microbial translocation and monocyte activation predict mortality in treated HIV. We examined whether substance use independently contributes to these pathophysiologic processes. DESIGN: Cross-sectional study at baseline for a randomized controlled trial. METHODS: HIV-positive, methamphetamine-using men who have sex with men (MSM) with undetectable HIV viral load (< 40 copies/mL) were enrolled. We examined if plasma biomarkers of monocyte activation and intestinal barrier integrity were associated with the following: 1) reactive urine toxicology results (Tox+) for stimulants (i...
January 23, 2018: AIDS
https://www.readbyqxmd.com/read/29368436/do-women-with-complex-alcohol-and-other-drug-use-histories-want-women-only-residential-treatment
#9
Joanne Neale, Charlotte N E Tompkins, Alison D Marshall, Carla Treloar, John Strang
BACKGROUND: Women-only addiction services tend to be provided on a poorly evidenced assumption that women want single-sex treatment. We draw upon women's expectations and experiences of women-only residential rehabilitation to stimulate debate on this issue. METHODS: Semi-structured interviews were undertaken with 19 women aged 25-44 years [currently in treatment (n = 9), successfully completed treatment (n = 5), left treatment prematurely (n = 5)]. All had histories of physical or sexual abuse, and relapses linked to relationships with men...
January 24, 2018: Addiction
https://www.readbyqxmd.com/read/29347834/acute-care-use-for-ambulatory-care-sensitive-conditions-in-high-cost-users-of-medical-care-with-mental-illness-and-addictions
#10
Jennifer M Hensel, Valerie H Taylor, Kinwah Fung, Rebecca Yang, Simone N Vigod
OBJECTIVE: The role of mental illness and addiction in acute care use for chronic medical conditions that are sensitive to ambulatory care management requires focussed attention. This study examines how mental illness or addiction affects risk for repeat hospitalization and/or emergency department use for ambulatory care-sensitive conditions (ACSCs) among high-cost users of medical care. METHOD: A retrospective, population-based cohort study using data from Ontario, Canada...
January 1, 2018: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/29343455/adolescent-social-stress-increases-anxiety-like-behavior-and-alters-synaptic-transmission-without-influencing-nicotine-responses-in-a-sex-dependent-manner
#11
Michael J Caruso, Nicole A Crowley, Dana E Reiss, Jasmine I Caulfield, Bernhard Luscher, Sonia A Cavigelli, Helen M Kamens
Early-life stress is a risk factor for comorbid anxiety and nicotine use. Because little is known about the factors underlying this comorbidity, we investigated the effects of adolescent stress on anxiety-like behavior and nicotine responses within individual animals. Adolescent male and female C57BL/6J mice were exposed to chronic variable social stress (CVSS; repeated cycles of social isolation + social reorganization) or control conditions from postnatal days (PND) 25-59. Anxiety-like behavior and social avoidance were measured in the elevated plus-maze (PND 61-65) and social approach-avoidance test (Experiment 1: PND 140-144; Experiment 2: 95-97), respectively...
January 14, 2018: Neuroscience
https://www.readbyqxmd.com/read/29341869/a-report-of-the-24th-annual-congress-on-women-s-health-workshop-on-transforming-women-s-health-from-research-to-practice
#12
Jennifer L Plank-Bazinet, Annie Sampson, Susan G Kornstein, Gregory G Germino, Marjorie Robert-Guroff, Stephen E Gilman, Cora Lee Wetherington, Nakela Cook, Terri L Cornelison, Lisa Begg, Janine Austin Clayton
Sex and gender are critical contributors to overall health and disease, and considering both in research informs the development of prevention strategies and treatment interventions for both men and women. The National Institutes of Health (NIH) Office of Research on Women's Health sponsored a preconference workshop on this topic at the 24th Annual Women's Health Congress, which was held in Crystal City, VA, in April 2016. The workshop featured presentations by NIH intramural and extramural scientists who presented data on a variety of topics including polycystic kidney disease, vaccine protection, depression, drug addiction, and cardiovascular disease...
January 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29339170/sub-anesthetic-doses-of-ketamine-attenuate-nicotine-self-administration-in-rats
#13
Amir H Rezvani, Yousef Tizabi, Susan Slade, Bruk Getachew, Edward D Levin
Smoking cessation strategies are of prime medical importance. Despite availability of various pharmacological agents in combating addiction to nicotine, more effective medications are needed. Based on recent findings, the glutamatergic system in the brain may provide novel targets. Here, we evaluated the effects of acute administration of sub-anesthetic doses of ketamine, an NMDA receptor antagonist, in both male and female Sprague-Dawley rats trained to self-administer nicotine. Animals were injected subcutaneously with 5, 7...
January 12, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29310047/differential-comt-expression-and-behavioral-effects-of-comt-inhibition-in-male-and-female-wistar-and-alcohol-preferring-rats
#14
Aqilah M McCane, Michael J DeLory, Maureen M Timm, Sarine S Janetsian-Fritz, Christopher C Lapish, Cristine L Czachowski
Polymorphisms of the catechol-O-methyl transferase (COMT) gene have been associated with alcoholism, suggesting that alterations in the metabolism of catecholamines may be a critical component of the neuropathology of alcoholism. In the current experiments, the COMT inhibitor tolcapone was utilized in an operant behavioral model of reinforcer-seeking and drinking to determine if this compound was capable of remediating the excessive seeking and drinking phenotype of the alcohol-preferring P rat. Tolcapone was administered to male and female alcohol-reinforced P and Wistar rats...
August 19, 2017: Alcohol
https://www.readbyqxmd.com/read/29306727/prevalence-associated-factors-and-impact-of-loneliness-and-interpersonal-problems-on-internet-addiction-a-study-in-chiang-mai-medical-students
#15
Sutapat Simcharoen, Manee Pinyopornpanish, Pattaraporn Haoprom, Pimolpun Kuntawong, Nahathai Wongpakaran, Tinakon Wongpakaran
INTRODUCTION: Internet addiction is common among medical students, and the prevalence is higher than the general population. Identifying and creating solutions for this problem is important. The aim of this study was to examine the prevalence and associated factors, particularly loneliness and interpersonal problems among Chiang Mai medical students. MATERIALS AND METHODS: Of 324 first to sixth year medical students, 56.8% comprised females with a mean age of 20...
December 28, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29302225/clinical-neuropsychiatric-considerations-regarding-nonsubstance-or-behavioral-addictions
#16
Marc N Potenza
Over the past several decades, non-substance-use behaviors like gambling, gaming, and sex have received greater consideration as possible foci of addictions. In this article, I will review the recent history and current status of non-substance or behavioral addictions. A main focus will involve gambling and gambling disorder, given that the latter is currently the sole non-substance addictive disorder described in the main text of the current (fifth) edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5)...
September 2017: Dialogues in Clinical Neuroscience
https://www.readbyqxmd.com/read/29297153/cigarette-smoking-and-schizophrenia-independently-and-reversibly-altered-intrinsic-brain-activity
#17
Huan Liu, Qi Luo, Wanyi Du, Xingbao Li, Zhiwei Zhang, Renqiang Yu, Xiaolu Chen, Huaqing Meng, Lian Du
Schizophrenia patients are at high risk for cigarette smoking, but the neurobiological mechanisms of this comorbid association are relatively unknown. Long-term nicotine intake may impact brain that are independently and additively associated with schizophrenia. We investigated whether altered intrinsic brain activity (iBA) related to schizophrenia pathology is also associated with nicotine addiction. Forty-two schizophrenia patients (21 smokers and 21 nonsmokers) and 21 sex- and age-matched healthy nonsmokers underwent task-free functional MRI...
January 3, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29295020/disclosing-sex-trading-histories-to-providers-barriers-and-facilitators-to-navigation-of-social-services-among-women-impacted-by-commercial-sexual-exploitation
#18
Lara Gerassi, Tonya E Edmond, Vanessa Fabbre, Abby Howard, Andrea J Nichols
Sex trafficking and commercial sexual exploitation (CSE) can lead to devastating health and mental health consequences for women, such as elevated rates of substance use, trauma, posttraumatic stress disorder, depression, sexually transmitted infections (STIs), and HIV. Consequently, engagement with services that address addiction, mental health, and housing, and provide general advocacy is critically important to women's increased safety, stabilization, and quality of life. The purpose of this study is to identify perceived barriers and facilitators to service access and engagement with social services among women involved in CSE...
December 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29289371/glucose-modulates-human-ventral-tegmental-activity-in-response-to-sexual-stimuli
#19
Martin Ulrich, Philipp Stauß, Georg Grön
BACKGROUND: Attribution of salience to sexual stimuli is mediated by the dopaminergic midbrain, including the ventral tegmental area (VTA). The existence of glucose-sensing neurons in the VTA, as suggested by animal studies, offers the opportunity to modulate aberrant salience coding involved in sexual disorders such as sexual addiction. Recent neuroimaging work supported that VTA activity in humans can be modulated by intravenously infusing a small bolus of glucose. However, that study used appetitive food stimuli, leaving the possibility that glucose modulation of VTA-mediated salience coding might be bound to this class of stimuli...
January 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29280290/sports-involvement-injury-history-and-non-medical-use-of-prescription-opioids-among-college-students-an-analysis-with-a-national-sample
#20
Jason A Ford, Corey Pomykacz, Philip Veliz, Sean Esteban McCabe, Carol J Boyd
BACKGROUND AND OBJECTIVES: The United States is in the midst of a prescription drug epidemic, particularly related to opioids. To more effectively deal with the devastating outcomes associated with non-medical use of prescription opioids (NUPO), research is needed to identify populations at increased risk. The current research builds on a small number of studies that have shown that adolescents involved in competitive sports are more likely to report NUPO. Specifically, we examine the relationship between athlete status, injury history, and NUPO among college students...
January 2018: American Journal on Addictions
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