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https://www.readbyqxmd.com/read/29227676/studying-sex-differences-in-animal-models-of-addiction-an-emphasis-on-alcohol-related-behaviors
#1
Elisa R Hilderbrand, Amy W Lasek
Animal models are essential for understanding the biological factors that contribute to drug and alcohol addiction and discovering new pharmacotherapies to treat these disorders. Alcohol (ethanol) is the most commonly abused drug in the world, and as the prevalence of alcohol use disorder (AUD) increases, so does the need for effective pharmacotherapies. In particular, treatments with high efficacy in the growing number of female AUD sufferers are needed. Female animals remain underrepresented in biomedical research and sex differences in the brain's response to alcohol are poorly understood...
December 11, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/29223914/cannabis-use-disorder-and-male-sex-predict-medical-cannabis-card-status-in-a-sample-of-high-risk-adolescents
#2
Janet Kim, Marilyn E Coors, Susan E Young, Kristen M Raymond, Christian J Hopfer, Tamara L Wall, Robin P Corley, Sandra A Brown, Joseph T Sakai
OBJECTIVE: To examine if a substance use disorder (SUD), especially cannabis use disorder in adolescence, predicts future medical cannabis card status among high-risk youth. METHODS: Data collection occurred in Denver and San Diego. We recruited adolescents, with or at high risk for SUD and conduct problems (hereafter probands) and their siblings (n=654). Baseline (Wave 1) assessments took place between 1999 and 2008, and follow-up (Wave 2) took place between 2010 and 2013...
December 2, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29223761/chemsex-risk-behaviours-and-sexually-transmitted-infections-among-men-who-have-sex-with-men-in-dublin-ireland
#3
Ronan W Glynn, Niamh Byrne, Siobhan O'Dea, Adam Shanley, Mary Codd, Eamon Keenan, Mary Ward, Derval Igoe, Susan Clarke
BACKGROUND: Drug use for or during sex ('chemsex') among MSM has caused concern, because of the direct effects of the drugs themselves, and because of an increased risk of transmission of sexually transmitted infections (STIs). This study aimed to assess the prevalence of chemsex, associated behaviours and STIs among attendees at Ireland's only MSM-specific sexual health clinic in Dublin over a six week period in 2016. METHODS: The questionnaire collected demographic data, information on sexuality and sexual practice, self-reported history of treatment for STIs, and chemsex use...
December 7, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29211192/tobacco-addiction-in-the-psychiatric-population-and-in-the-general-population
#4
Renata Marques de Oliveira, Jair Lício Ferreira Santos, Antonia Regina Ferreira Furegato
OBJECTIVE: To estimate the degree of tobacco addiction and identify independently associated factors by comparing the psychiatric population of secondary and tertiary care with the general population of the primary healthcare network. METHOD: This is a cross-sectional epidemiological study, conducted in a municipality of São Paulo, with 134 smokers of a Mental Health Outpatient Unit (MHOU), a Psychiatric Hospital (PH), and a Primary Healthcare Unit (PHU). Data were collected by means of individual interviews, recorded on a mobile device...
December 4, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/29191171/self-assessment-of-the-mental-health-status-in-older-adults-in-poland-a-cross-sectional-study
#5
Mateusz Cybulski, Lukasz Cybulski, Elzbieta Krajewska-Kulak, Urszula Cwalina
BACKGROUND: Demographic aging of society poses numerous challenges, including the provision of health care to the elderly population. According to World Health Organization data, the most frequent mental disorders in the senior population are: dementia, depression, and drug and alcohol addiction. The aim of this study was to subjectively assess mental health status (the severity of non-psychotic symptoms of mental functions and depressive symptoms) in older adults of Bialystok (Poland)...
December 1, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29183920/reassessing-the-importance-of-lost-pleasure-associated-with-smoking-cessation-implications-for-social-welfare-and-policy
#6
Terry Frank Pechacek, Pratibha Nayak, Paul Slovic, Scott R Weaver, Jidong Huang, Michael P Eriksen
INTRODUCTION: Benefit-cost analyses of tobacco regulations include estimates of the informed choice of smokers to continue smoking. Few studies have focused on subjective feelings associated with continued smoking. This study estimates how smoker discontent and regret relate to risk perceptions and health concerns. METHODS: We analysed data from a 2015 nationally representative, online survey of 1284 US adult current smokers. Information was collected on regret, intention to quit, perceived addiction, risk perceptions and health concerns...
November 28, 2017: Tobacco Control
https://www.readbyqxmd.com/read/29166482/abortion-and-sex-related-conditions-in-substance-dependent-brazilian-patients
#7
Alessandra Diehl, Sandra Cristina Pillon, Manoel Antonio Dos Santos, Ronaldo Laranjeira
Abortion is a very sensitive issue with relevance to public health; however few clinical or population-based studies have examined induced abortion among drug users. The study aims to evaluate the prevalence of induced abortion and sex-related conditions in an inpatient drug user sample. A cross-sectional design study was conducted in an inpatient addiction treatment unit in São Paulo, Brazil, with a sample of 616 patients, aged 18-75. Sociodemographic data, sexual behavior, and dependence severity were evaluated in relation to induced abortion...
November 21, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29161174/the-telescoping-phenomenon-origins-in-gender-bias-and-implications-for-contemporary-scientific-inquiry
#8
Katherine R Marks, Claire D Clark
BACKGROUND: In an article published in International Journal of the Addictions in 1989, Nick Piazza and his coauthors described "telescoping," an accelerated progression through "landmark symptoms" of alcoholism, among a sample of recovering women. OBJECTIVES: The aim of this critical analysis is to apply a feminist philosophy of science to examine the origins of the framework of telescoping research and its implications for contemporary scientific inquiry. METHODS: A feminist philosophy of science framework is outlined and applied to key source publications of telescoping literature drawn from international and United States-based peer-reviewed journals published beginning in 1952...
November 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/29160596/chronic-pain-and-opioid-abuse-factors-associated-with-health-related-quality-of-life
#9
Jermaine D Jones, Jonathan S Vogelman, Rachel Luba, Mudassir Mumtaz, Sandra D Comer
BACKGROUND AND OBJECTIVES: While research on the separate relationships between health-related quality of life (HRQOL) and chronic pain, and HRQOL and opioid abuse has been sparse, even less work has investigated the factors associated with HRQOL in individuals who have both chronic pain and meet criteria for opioid use disorder. The data presented in this analysis should allow a better understanding the factors important to quality of life among this dual-diagnosed population. METHODS: Individuals with dual diagnoses of chronic pain and opioid use disorder were recruited for clinical research studies at Columbia University Medical Center...
December 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/29158111/brain-derived-neurotrophic-factor-bdnf-determines-a-sex-difference-in-cue-conditioned-alcohol-seeking-in-rats
#10
Samuel J Hogarth, Emily J Jaehne, Maarten van den Buuse, Elvan Djouma
Alcohol use disorder is a detrimental addictive disease that develops through prolonged ethanol exposure and regular intoxication. However, the changes in the underlying neurobiology leading to alcohol addiction remain unclear. Brain-Derived Neurotrophic Factor (BDNF) is implicated in substance abuse disorders including alcoholism. As the vast majority of previous animal model studies have concentrated on males only, the aim of this study was to determine whether endogenous BDNF mediates alcohol seeking in a sex-specific manner...
November 17, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29157683/unique-characteristics-of-high-cost-users-of-medical-care-with-comorbid-mental-illness-or-addiction-in-a-population-based-cohort
#11
Jennifer M Hensel, Valerie H Taylor, Kinwah Fung, Claire de Oliveira, Simone N Vigod
OBJECTIVE: To understand whether high-cost users of medical care with and without comorbid mental illness or addiction differ in terms of their sociodemographic and health characteristics. Unique characteristics would warrant different considerations for interventions and service design aimed at reducing unnecessary health care utilization and associated costs. METHODS: From the top 10% of Ontarians ranked by total medical care costs during fiscal year 2011/2012 (N = 314,936), prior 2-year mental illness or addiction diagnoses were determined from administrative data...
October 16, 2017: Psychosomatics
https://www.readbyqxmd.com/read/29154688/substance-use-and-cognitive-function-as-drivers-of-condomless-anal-sex-among-hiv-positive-gay-bisexual-and-other-men-who-have-sex-with-men-aged-50-and-older-the-gold-studies
#12
Sandra A Kupprat, Kristen D Krause, Danielle C Ompad, Perry N Halkitis
PURPOSE: Substance use has been linked to the sexual transmission of HIV among gay, bisexual, and other men who have sex with men (MSM) across the lifespan. Among older, HIV-positive, MSM populations, cognitive dysfunction associated with age and HIV disease progression also may play a role in sexual risk-taking. People aged 50 years and older represent a growing proportion of the overall HIV-positive population. This study aimed to explore relationships between substance use and cognitive function, and their impact on condomless anal sex (CAS) among HIV-positive gay, bisexual, and other MSM aged 50 years and older...
November 20, 2017: LGBT Health
https://www.readbyqxmd.com/read/29135448/-the-psychotherapy-of-male-patient-with-sex-addiction
#13
Edina Hamvas, Tamás Tényi
No abstract available.
2017: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
https://www.readbyqxmd.com/read/29129680/existential-issues-in-sexual-medicine-the-relation-between-death-anxiety-and-hypersexuality
#14
REVIEW
Daniel N Watter
INTRODUCTION: Current sex therapy and sexual medicine protocols often ignore the existential dilemmas associated with sexual dysfunction and other problematic sexual problems. This oversight is especially apparent when assessing and treating the controversial phenomenon of hypersexuality, or "sexual addiction." A deeper understanding of the existential concept of death anxiety could offer an alternative treatment paradigm that might lead to a more effective treatment outcome. AIM: To explore the relation between the existential phenomenon of death anxiety and hypersexuality (ie, sexual addiction) and present an evaluation and treatment paradigm that is rooted in existential psychotherapy, a form of psychotherapy that is a deeply life-affirming and dynamic approach to therapy that focuses on concerns rooted in the individual's existence...
November 9, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29121158/opioid-use-by-patients-after-rhinoplasty
#15
Sagar Patel, Angela Sturm, Michael Bobian, Peter F Svider, Giancarlo Zuliani, Russell Kridel
Importance: Given the increase in opioid addiction and overdose in the United States, reasoned opioid use after outpatient surgery may affect prescription medication abuse. Objectives: To examine patient use of opioids after rhinoplasty and establish an optimal postrhinoplasty pain management regimen. Design, Setting, and Participants: In this case series, opioid use was evaluated in 62 patients who underwent rhinoplasty performed by 3 fellowship-trained facial plastic surgeons, 2 in private practice in Texas and 1 in an academic setting in Michigan, from February 2016 to September 2016...
November 9, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/29115703/moderators-of-response-to-sertraline-versus-placebo-among-recently-abstinent-cocaine-dependent-patients-a-retrospective-analysis-of-two-clinical-trials
#16
Maryam Bashiri, Michael J Mancino, Virginia A Stanick, Jeff Thostenson, Thomas R Kosten, Alison H Oliveto
BACKGROUND AND OBJECTIVES: Moderators of treatment response to serotonin reuptake inhibitor sertraline (SRT) for cocaine dependence were assessed in two randomized, double blind, placebo-controlled clinical trials. METHODS: Generalized estimating equation modeling was performed on data from cocaine-dependent volunteers randomized to receive SRT or placebo (N = 126) who completed >2-week drug-free residential portions of the 12-week trials, in which subsequent outpatient treatment (weeks 3-12) included weekly cognitive behavioral therapy and thrice-weekly supervised urine toxicology...
December 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/29108963/influences-of-social-reward-experience-on-behavioral-responses-to-drugs-of-abuse-review-of-shared-and-divergent-neural-plasticity-mechanisms-for-sexual-reward-and-drugs-of-abuse
#17
REVIEW
Lauren N Beloate, Lique M Coolen
Different factors influence the development of drug addiction in humans, including social reward experiences. In animals, experience with social rewards, such as sexual behavior, pair bonding, social and environmental enrichment, can be protective. However, loss or lack of social rewards can lead to a vulnerability to drug-seeking behavior. The effects of social reward experience on drug-seeking behavior are associated with changes in the neural pathways that control drug-related behavior. This review will provide an introduction and overview of the mesolimbic pathway and the influence of social reward experience on drug-seeking behavior in rodents...
November 3, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29106659/biological-and-psychological-factors-associated-with-smoking-abstinence-six-years-post-stroke
#18
Rosa Suñer-Soler, Armand Grau-Martín, Mikel Terceno, Yolanda Silva, Antoni Davalos, Juan Manuel Sánchez, Silvia Font-Mayolas, Eugenia Gras, Joana Rodrigo, Martha Kazimierczak, Carmen Malagón, Joaquín Serena
Introduction: Tobacco use is a public health problem causing high morbidity and mortality, including stroke. This study evaluates predictive factors of smoking cessation in the long term after stroke. Methods: We followed a cohort of 110 consecutive smokers with stroke for up to 6 years. Sociodemographic variables, stroke severity, insular involvement, stage of change in smoking habit before stroke and disruption of addiction variable (smoking cessation, absence of relapses, having stopped smoking without difficulties and not having had urge) were evaluated...
July 4, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29098678/nutrition-support-therapy
#19
Li-Jun Xiao, Ran Tao
In most addictions, serious nutritional deficiencies of major proteins, fats, vitamins and minerals exist which prevent their capability to digest carbohydrates efficiently. This review aims to point out some treatment approaches in nutrition management for alcohol addiction, drug addiction, food addiction, Internet addiction and sex addiction, according to existing literatures.
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29098672/similarities-and-differences-in-diagnostic-scales
#20
Bin Xuan, Peng Li, Liping Yang, Mingzhu Li, Jing Zhou
A scale plays an important role as a diagnostic tool in discriminating between addicts and non-addicts. At the beginning of this chapter, we have briefly introduced the development of substance and non-substance addiction scales, which not only include alcohol addiction, nicotine addiction and pathological gambling, but also the disputed exercise and sex addiction. While it was found that almost all addiction scales contain items relating to social impairment, preoccupation, withdrawal, and tolerance, the variability is more pronounced with non-substance addiction scales...
2017: Advances in Experimental Medicine and Biology
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