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https://www.readbyqxmd.com/read/28727662/paraphilic-thoughts-behaviors-and-sex-addiction-in-a-sample-of-persons-who-use-drugs-a-cross-sectional-study
#1
Jales Clemente, Sandra Cristina Pillon, Jair de Jesus Mari, Claudio Jeronimo da Silva, Paulo Roberto Henrique Santana, Alessandra Diehl
OBJECTIVE: The aim of this study was to evaluate the prevalence of paraphilic thoughts/behaviors (including paraphilic disorders) with and without sexual addiction and sexual-related conditions in a sample of substance disorder patients. METHODS: This was a cross-sectional study of substance-dependent individuals who sought outpatient treatment in São Paulo, Brazil. Data included sociodemographic information, drug of choice, responses to questions about sexual behavior, and to the following standardized questionnaires: (a) Sexual Addiction Screening Test, and (b) Childhood Trauma Questionnaire...
July 19, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28724038/sexual-addiction-in-drug-addicts-the-impact-of-drug-of-choice-and-poly-addiction
#2
Nelson Antonio, Alessandra Diehl, Marcelo Niel, Sandra Pillon, Lilian Ratto, Maria Carolina Pinheiro, Dartiu Silveira, Thais Zelia Otani, Victor Otani, Quirino Cordeiro, Ricardo Ushida
Objective: To compare the risk of comorbid sexual addiction in a sample of individuals with a diagnosis of substance dependence, stratifying the sample by drug of choice as well as by mono versus polysubstance addiction. Method: All data were collected at Santa Casa de São Paulo, Brazil. The study sample comprised all alcohol or drug dependents admitted to the Addiction Treatment Unit between November 2013 and August 2014. A generalized linear model with a binomial distribution was performed to compare the odds of having a Sexual Addiction Screening Test (SAST) score greater than 6 points in the subgroups analyzed...
May 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28716656/atomoxetine-in-abstinent-cocaine-users-cognitive-subjective-and-cardiovascular-effects
#3
Elise E DeVito, Aryeh I Herman, Noah S Konkus, Huiping Zhang, Mehmet Sofuoglu
No pharmacotherapies are approved for the treatment of cocaine use disorders (CUD). Behavioral treatments for CUD are efficacious for some individuals, but recovery rates from CUD remain low. Cognitive impairments in CUD have been linked with poorer clinical outcomes. Cognitive enhancing pharmacotherapies have been proposed as promising treatments for CUD. Atomoxetine, a norepinephrine transporter inhibitor, shows potential as a treatment for CUD based on its efficacy as a cognitive enhancer in other clinical populations and impact on addictive processes in preclinical and human laboratory studies...
July 14, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28711378/subjective-perception-of-cocaine-reward-in-mice-assessed-by-a-single-exposure-place-preference-sepp-paradigm
#4
Annika H Runegaard, Kathrine Louise Jensen, Ditte Dencker, Gitta Wörtwein, Ulrik Gether
BACKGROUND: The potential of abused drugs to induce addiction and compulsive drug-related behavior is associated with their ability to alter dopamine signaling. Dopamine plays a key role in reward signaling and it has been of great interest to investigate how various drugs of abuse alter reward-related behavior. COMPARISON WITH EXISTING METHODS: In rodents, the rewarding effects of drugs have often been assessed in self-administration or place preference paradigms; both involving repeated drug exposure and weeks of training and testing...
July 12, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28703074/serum-ionic-dysequilibria-in-clinical-opioid-dependence-cross-sectional-and-longitudinal-studies
#5
A S Reece, A Norman, G K Hulse
INTRODUCTION: Despite an increasing awareness that the activity of excitable membranes is determined by the underlying ionic gradients across them, and their importance in drug dependency, we were not able to identify any reports of comparing the electrolyte composition of opioid-dependent and non-addicted controls. METHODS: Linear regression was used to compare clinical pathology blood results taken from 2699 opioid-dependent patients (ODP) and 5307 medical control (MC) patients on a total of 21,734 occasions for the period 1995-2015...
August 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28697679/increased-synthetic-drug-abuse-and-trends-in-hiv-and-syphilis-prevalence-among-female-drug-users-from-2010-2014-from-beijing-china
#6
Yanming Sun, Wei Guo, Guiying Li, Shufang He, Hongyan Lu
The objective of this study was to monitor the trend of addiction drug use and its relationship with sexually transmitted infections (STIs) among female drug users (FDUs). Serial cross-sectional surveys were conducted during 2010-2014 among FDUs in Beijing to collect information on addiction drug usage, sexual behaviors, and STI prevalence. Characteristics were analyzed and compared between traditional and synthetic drug users among FDUs by logistic regression method. A total of 3859 FDUs were surveyed during 2010-2014, with the median age being 32...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28687897/hypersexuality-a-critical-review-and-introduction-to-the-sexhavior-cycle
#7
Michael T Walton, James M Cantor, Navjot Bhullar, Amy D Lykins
An empirical review of hypersexuality is timely as "compulsive sexual behavior" is being considered as an impulse control disorder for inclusion in the forthcoming International Classification of Diseases, 11th ed. Specifically, hypersexuality has been conceptualized in the literature as the inability to regulate one's sexual behavior that is a source of significant personal distress. Various theoretical models have been posited in an attempt to understand the occurrence of hypersexuality, although disagreement about these divergent conceptualizations of the condition has made assessment and treatment of hypersexual clients more challenging...
July 7, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28672410/-prescription-of-benzodiazepines-and-z-drugs-by-german-general-practitioners-a-cross-sectional-study
#8
Dirk Moßhammer, Hannah Haumann, Rainer Muche, David Scheub, Stefanie Joos, Gunter Laux
Background Due to their addictive potential, benzodiazepine (BZ) and non-benzodiazepine-agonists (NBZ, so-called Z-drugs) should be taken no longer than 6 weeks. BZ and NBZ are primarily prescribed by general practitioners (GPs). Therefore, we aimed to analyze GPs' data on the patients collective, the amount of BZ/NBZ prescribed and the rate of private prescriptions. Methods We analyzed person years of 2-year intervals from 2009 to 2014 of the primary care CONTENT register that contains routine data from 31 general practitioners' practices...
July 3, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28645061/the-neurochemical-consequences-of-methamphetamine-self-administration-in-male-and-female-rats
#9
Andrew Johansen, Lisa M McFadden
BACKGROUND: Methamphetamine (METH) is an addictive substance that is used in both males and females. Few preclinical studies have focused on understanding sex-differences in the neurochemical consequences of contingent METH. The purpose of the current study was to investigate potential sex-differences in the neurochemical consequences of METH self-administration. METHODS: Male and female adult rats were given extended access to METH or saline self-administration for 7d...
June 6, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28642080/impact-of-juvenile-chronic-stress-on-adult-cortico-accumbal-function-implications-for-cognition-and-addiction
#10
REVIEW
Michael J Watt, Matthew A Weber, Shaydel R Davies, Gina L Forster
Repeated exposure to stress during childhood is associated with increased risk for neuropsychiatric illness, substance use disorders and other behavioral problems in adulthood. However, it is not clear how chronic childhood stress can lead to emergence of such a wide range of symptoms and disorders in later life. One possible explanation lies in stress-induced disruption to the development of specific brain regions associated with executive function and reward processing, deficits in which are common to the disorders promoted by childhood stress...
June 19, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28628620/prevalence-and-determinants-of-online-sex-use-in-the-german-population
#11
Manfred E Beutel, Sebastian Giralt, Klaus Wölfling, Yve Stöbel-Richter, Claudia Subic-Wrana, Iris Reiner, Ana Nanette Tibubos, Elmar Brähler
INTRODUCTION: The unlimited access to sexual features in the World Wide Web has raised concerns about excessive and problematic online-sex use. However, little is known about antecedents of internet-sex use of different intensity. Based on a representative German sample of 2,522 participants between the ages of 14 and 97 years, the aims of the present study were (1) to determine the prevalence rates of online-sex users with the short version (ISSTGSV) of the Internet Sex Screening Test and (2) to associate online-sex use with anxious vs...
2017: PloS One
https://www.readbyqxmd.com/read/28624586/modeling-the-development-of-drug-addiction-in-male-and-female-animals
#12
REVIEW
Wendy J Lynch
An increasing emphasis has been placed on the development and use of animal models of addiction that capture defining features of human drug addiction, including escalation/binge drug use, enhanced motivation for the drug, preference for the drug over other reward options, use despite negative consequences, and enhanced drug-seeking/relapse vulnerability. The need to examine behavior in both males and females has also become apparent given evidence demonstrating that the addiction process occurs differently in males and females...
June 15, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28623937/the-association-of-lipid-metabolism-relative-gene-polymorphisms-and-ischemic-stroke-in-han-and-uighur-population-of-xinjiang
#13
Yun-Hua Yue, Ling-Yun Liu, Liang Hu, You-Mei Li, Jie-Ping Mao, Xiao-Ying Yang, Na-Mu Dila
BACKGROUND: The present study is aimed to evaluate difference of lipid metabolism related gene single nucleotide polymorphisms (SNPs) with ischemic stroke (IS) in Han and Uighur population of Xinjiang, China. METHODS: Four hundred eight patients with ischemic stroke and 347 unrelated healthy individuals of age and sex matched were genotyped for Apolipoprotein A5 (ApoA5), lipoprotein lipase (LPL), Cholesteryl ester transfer protein (CETP) and low-density lipoprotein receptor (LDL-R) genes...
June 17, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28617565/psychotropic-medications-in-swedish-homicide-victims-and-offenders-a-forensic-toxicological-case-control-study-of-adherence-and-recreational-use
#14
Jonatan Hedlund, Jonas Forsman, Joakim Sturup, Thomas Masterman
OBJECTIVE: We aimed to assess the extent to which adherence to, and recreational use of, psychotropic medications influence the risk of homicide offending and victimization. METHODS: We conducted a population-based case-control study by way of linking a nationwide registry of dispensed prescriptions with a forensic-toxicological database. Homicide victims (n = 200) and offenders (n = 105) were identified for the years 2007-2009 and vehicle-accident controls (n = 1,643) for the years 2006-2013...
June 6, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28611692/development-of-a-mobile-phone-addiction-craving-scale-and-its-validation-in-a-spanish-adult-population
#15
José De-Sola, Hernán Talledo, Gabriel Rubio, Fernando Rodríguez de Fonseca
In some people, problematic cell phone use can lead to situations in which they lose control, similar to those observed in other cases of addiction. Although different scales have been developed to assess its severity, we lack an instrument that is able to determine the desire or craving associated with it. Thus, with the objective of evaluating craving for cell phone use, in this study, we develop and present the Mobile Phone Addiction Craving Scale (MPACS). It consists of eight Likert-style items, with 10 response options, referring to possible situations in which the interviewee is asked to evaluate the degree of restlessness that he or she feels if the cell phone is unavailable at the moment...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28600000/sex-specific-effects-of-developmental-alcohol-exposure-on-cocaine-induced-place-preference-in-adulthood
#16
Victoria A Macht, Sandra J Kelly, Justin T Gass
Fetal Alcohol Syndrome (FAS) is associated with high rates of drug addiction in adulthood. One possible basis for increased drug use in this population is altered sensitivity to drug-associated contexts. This experiment utilized a rat model of FASD to examine behavioral and neural changes in the processing of drug cues in adulthood. Alcohol was given by intragastric intubation to pregnant rats throughout gestation and to rat pups during the early postnatal period (ET group). Controls consisted of a non-treated group (NC) and a pair-fed group given the intubation procedure without alcohol (IC)...
June 6, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28599850/tobacco-and-alcohol-use-during-adolescence-interactive-mechanisms-in-animal-models
#17
REVIEW
Yael Abreu-Villaça, Alex C Manhães, Thomas E Krahe, Claudio C Filgueiras, Anderson Ribeiro-Carvalho
There is a strong association between tobacco smoking and the consumption of alcoholic beverages. When compared to the effects of either drug on its own, the combined use may lead to worsened outcomes, such as less successful quitting attempts and increased likelihood of developing mood disorders. Co-consumption most frequently begins during adolescence, a developmental period that is characterized by an increased risk for substance use disorders. However, to date, most studies that have contributed to the current state of knowledge on the mechanisms that underlie tobacco or alcohol use/abuse, and their consequences, adopted adult animal models...
June 6, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28598798/level-of-internet-use-among-greek-adolescents-with-type-1-diabetes
#18
Katerina Daniilidou, Panagiota Triantafyllou, Maria Resta, Meropi Dimitriadou, Athanasios Christoforidis
Background Compulsive Internet use has emerged as a contemporary addictive behavior. Our aim was to investigate the reasons for Greek adolescents with type 1 diabetes mellitus (T1DM) and their families to use the Internet and additionally to investigate the level of Internet use and its associations to demographic, socio-economic parameters and glycemic control. Methods Patients with T1DM, aged >12 years and their parents were recruited during their regular visits to the Pediatric Diabetes Clinic. A similar group of healthy children, age- and sex-matched served as a control group...
June 9, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28587607/design-of-a-syndemic-based-intervention-to-facilitate-care-for-men-who-have-sex-with-men-with-high-risk-behaviour-the-syn-bas-in-randomized-controlled-trial
#19
Roel C A Achterbergh, Jannie J van der Helm, Wim van den Brink, Henry J C de Vries
BACKGROUND: Men who have sex with men (MSM) constitute a risk group for sexual transmitted infections (STIs), including HIV. Despite counselling interventions, risk behaviour remains high. Syndemic theory holds that psychosocial problems often co-occur, interact and mutually reinforce each other, thereby increasing high risk behaviours and co-occurring diseases. Therefore, if co-occurring psychosocial problems were assessed and treated simultaneously, this might decrease high risk behaviour and disease...
June 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28586701/the-extent-of-and-factors-associated-with-self-reported-overdose-and-self-reported-receipt-of-naloxone-among-people-who-inject-drugs-pwid-in-england-wales-and-northern-ireland
#20
Charlotte O'Halloran, Katelyn Cullen, Jaquelyn Njoroge, Lucy Jessop, Josie Smith, Vivian Hope, Fortune Ncube
BACKGROUND: Overdose is a major cause of death among PWID, and for opioid overdoses naloxone administration can reduce harm. However, globally there is limited national level data on the extent of non-fatal overdose and naloxone uptake. The first national level data on the extent of self-reported overdose and self-reported receipt of naloxone among UK PWID, providing a baseline to monitor the impact of the recent policy change regarding naloxone availability, is presented. METHODS: Data on self-reported overdose and receipt of naloxone during the preceding year for 2013-2014 from a national survey of PWID was analysed...
June 3, 2017: International Journal on Drug Policy
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