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https://www.readbyqxmd.com/read/28637302/re-risk-prediction-for-epithelial-ovarian-cancer-in-11-united-states-based-case-control-studies-incorporation-of-epidemiologic-risk-factors-and-17-confirmed-genetic-loci
#1
(no author information available yet)
No abstract text is available yet for this article.
June 16, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28637279/high-dimensional-multivariate-mediation-with-application-to-neuroimaging-data
#2
Oliver Y Chén, Ciprian Crainiceanu, Elizabeth L Ogburn, Brian S Caffo, Tor D Wager, Martin A Lindquist
Mediation analysis is an important tool in the behavioral sciences for investigating the role of intermediate variables that lie in the path between a treatment and an outcome variable. The influence of the intermediate variable on the outcome is often explored using a linear structural equation model (LSEM), with model coefficients interpreted as possible effects. While there has been significant research on the topic, little work has been done when the intermediate variable (mediator) is a high-dimensional vector...
June 15, 2017: Biostatistics
https://www.readbyqxmd.com/read/28637265/importance-of-carbapenemase-production-detection-in-carbapenem-resistant-enterobacteriaceae-looking-beyond-epidemiological-purposes
#3
Adriana Jimenez, Lilian Abbo, Merhawi T Gebrezgi
No abstract text is available yet for this article.
June 16, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28637226/epidemiologic-risk-factors-for-in-situ-and-invasive-breast-cancer-among-postmenopausal-women-in-the-nih-aarp-diet-and-health-study
#4
Maeve Mullooly, Zeina G Khodr, Cher M Dallal, Sarah J Nyante, Mark E Sherman, Roni Falk, Linda M Liao, Jeffrey Love, Louise A Brinton, Gretchen L Gierach
Comparing risk factor associations between invasive breast cancers and possible precursors may further understanding of factors related to initiation versus progression. Accordingly, among 190,325 postmenopausal participants in the National Institutes of Health-AARP Diet and Health Study (1995-2011), we compared risk factor associations between incident ductal carcinoma in situ (DCIS: n = 1,453) and invasive ductal carcinomas (n = 7,525) and lobular carcinoma in situ (LCIS: n = 186) and invasive lobular carcinomas (n = 1,191)...
June 16, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28637225/characteristics-of-escherichia-coli-isolated-from-broiler-chickens-with-colibacillosis-in-commercial-farms-from-a-common-hatchery
#5
H Ozaki, Y Matsuoka, E Nakagawa, T Murase
To investigate the epidemiologic aspects of colibacillosis in broiler chickens, 83 Escherichia coli isolates obtained from the pericarditis and perihepatitis lesions in broiler chickens from 4 commercial farms, 5 isolates recovered from 5 samples of yolk sac contents that were pooled from 25 emaciated chicks, and 4 fecal isolates obtained from a hatchery that supplied chicks to the 4 commercial farms mentioned above were genetically and bacteriologically characterized. Using pulsed-field gel electrophoresis (PFGE), a total of 92 isolates were classified into 33 pulsotypes...
June 20, 2017: Poultry Science
https://www.readbyqxmd.com/read/28637058/evaluation-of-cases-of-abdominal-wall-endometriosis-at-universidade-estadual-de-campinas-in-a-period-of-10-years
#6
Daniela Angerame Yela, Lucas Trigo, Cristina Laguna Benetti-Pinto
Purpose To determine the clinical and epidemiological characteristics of abdominal wall endometriosis (AWE), as well as the rate and recurrence factors for the disease. Methods A retrospective study of 52 women with AWE was performed at Universidade Estadual de Campinas from 2004 to 2014. Of the 231 surgeries performed for the diagnosis of endometriosis, 52 women were found to have abdominal wall endometriosis (AWE). The frequencies, means and standard deviations of the clinical characteristics of these women were calculated, as well as the recurrence rate of AWE...
June 21, 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28637036/differentiating-incident-from-recurrent-stroke-using-administrative-data-the-impact-of-varying-lengths-of-look-back-periods-on-the-risk-of-misclassification
#7
John Mark Worthington, Melina Gattellari, Chris Goumas, Bin Jalaludin
BACKGROUND/AIMS: Administrative data are widely used to monitor epidemiological trends in stroke and outcomes; yet there is scant empirical guidance on how to best differentiate incident from recurrent stroke. METHODS: We identified all hospital admissions in New South Wales, Australia, with a principal stroke diagnosis from July 1, 2013 to June 30, 2014, linked to 12 years of previous admissions. We calculated the proportion of cases identified with a prior stroke to determine the number of years of look-back required to minimise misclassification of incident and recurrent strokes...
June 22, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28636999/impact-of-insurance-status-on-the-survival-of-gallbladder-cancer-patients
#8
Zhiqiang Chen, Wen Gao, Liyong Pu, Long Zhang, Guoyong Han, Qin Zhu, Xiangcheng Li, Jindao Wu, Xuehao Wang
The prognostic significance of insurance status has been investigated in many types of malignancies, however, its impact on gallbladder cancer is yet not known. The purpose of this study was to determine the relationship between insurance status and gallbladder cancer survival. We searched the Surveillance, Epidemiology, and End Results dataset, and identified 1,729 gallbladder cancer cases. Kaplan-Meier methods and multivariable Cox regression models were used to analyze survival outcomes and risk factors...
June 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/28636993/polymorphisms-and-expression-pattern-of-circular-rna-circ-itch-contributes-to-the-carcinogenesis-of-hepatocellular-carcinoma
#9
Wenzhi Guo, Jiakai Zhang, Dongyu Zhang, Shengli Cao, Gongquan Li, Shuijun Zhang, Zhihui Wang, Peihao Wen, Han Yang, Xiaoyi Shi, Jie Pan, Hua Ye
Hepatocellular carcinoma (HCC) ranks the sixth most common cancer and the third cause of cancer-related mortality worldwide. Recent studies identified that circ-ITCH Suppresses mutiple cancers proliferation via inhibiting the Wnt/beta-Catenin pathway. In current study, conducted a genetic association study together with epidemiological follow-up study to delineate the role of circ-ITCH in the development and progression of HCC. we found rs10485505 (adjusted OR =1.18; 95% CI=1.06-1.31; P value =3.1×10-3) and rs4911154 (adjusted OR =1...
June 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28636983/the-influence-of-marital-status-on-survival-in-patients-with-oral-tongue-squamous-cell-carcinoma
#10
Wei Sun, Zeting Qiu, Wulin Tan, Zhongqi Liu, Zhongxing Wang, Wenqi Huang, Minghui Cao
Marital status was found to be an independent prognostic factor for survival in several cancers. However related researches of oral tongue squamous cell carcinoma (OTSCC) are still rare. We explored the Surveillance, Epidemiology, and End Results (SEER) program and finally identified 14,194 patients with OTSCC. Kaplan-Meier analysis and multivariate Cox regression models were used to distinguish risk factors for overall survival (OS) and tumor cause-specific survival (TCSS). Widowed patients had the highest percentage of female, highest average ages and more prevalence with localized SEER Stage significantly, while patients in the single group were younger than other groups...
June 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/28636889/complications-of-hematopoietic-stem-transplantation-fungal-infections
#11
REVIEW
Ali S Omrani, Reem S Almaghrabi
Patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) are at increased risk of invasive fungal infections, especially during the early neutropenic phase and severe graft-versus-host disease. Mold-active prophylaxis should be limited to the highest risk groups. Empiric antifungal therapy for HSCT with persistent febrile neutropenia is associated with unacceptable response rates, unnecessary antifungal therapy, increased risk of toxicity, and inflated costs. Empiric therapy should not be a substitute for detailed work up to identify the cause of fever in such patients...
June 13, 2017: Hematology/oncology and Stem Cell Therapy
https://www.readbyqxmd.com/read/28636866/prevalence-and-risk-factors-of-chlamydia-trachomatis-neisseria-gonorrhoeae-trichomonas-vaginalis-and-other-sexually-transmissible-infections-among-women-attending-antenatal-clinics-in-three-provinces-in-papua-new-guinea-a-cross-sectional-survey
#12
Lisa M Vallely, Pamela Toliman, Claire Ryan, Glennis Rai, Johanna Wapling, Carolyn Tomado, Savarina Huliafi, Gloria Munnull, Patricia Rarau, Suparat Phuanukoonnon, Handan Wand, Peter Siba, Glen D L Mola, John M Kaldor, Andrew J Vallely
Background Papua New Guinea (PNG) is estimated to have among the highest prevalences of HIV and sexually transmissible infections (STIs) of any Asia-Pacific country, and one of the highest burdens of maternal syphilis globally. The prevalence of curable STIs, such as Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Trichomonas vaginalis (TV), among pregnant women in PNG is relatively unknown. METHODS: A cross-sectional bio-behavioural survey to investigate the epidemiology of CT, NG, TV and other STIs among pregnant women in three provinces of PNG was undertaken...
October 2016: Sexual Health
https://www.readbyqxmd.com/read/28636768/driving-aggression-and-anxiety-intersections-assessment-and-interventions
#13
Heidi M Zinzow, Stephanie M Jeffirs
OBJECTIVE: Driving aggression and anxiety are significant contributors to risky driving and motor vehicle crashes (MVCs), which are leading causes of U.S. morbidity and mortality. Even though aggression and anxiety can be conceptualized as related features of the fight-or-flight response, literature on these topics has not been integrated. Driving aggression and anxiety are also transdiagnostic constructs that span multiple psychiatric disorders. Assessment and treatment of these complex problems must be understood to reduce the public health burden of MVCs...
June 21, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28636692/rethinking-the-current-american-joint-committee-on-cancer-tnm-staging-system-for-medullary-thyroid-cancer
#14
Mohamed Abdelgadir Adam, Samantha Thomas, Sanziana A Roman, Terry Hyslop, Julie A Sosa
Importance: Controversy exists around the American Joint Committee on Cancer (AJCC) TNM staging system for medullary thyroid cancer (MTC). Because of the rarity of the disease and limited available data, the staging system for MTC has been largely extrapolated from staging for differentiated thyroid cancer. Objectives: To evaluate how well the current (seventh and eighth editions) AJCC TNM staging system correlates with survival for patients with MTC and to suggest a possible revision...
June 21, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28636666/molecular-and-microbiological-report-of-a-hospital-outbreak-of-ndm-1-carrying-enterobacteriaceae-in-mexico
#15
Paola Bocanegra-Ibarias, Elvira Garza-González, Rayo Morfín-Otero, Humberto Barrios, Licet Villarreal-Treviño, Eduardo Rodríguez-Noriega, Ulises Garza-Ramos, Santiago Petersen-Morfin, Jesus Silva-Sanchez
OBJECTIVES: To characterize the microbiological, molecular and epidemiological data of an outbreak of carbapenem-resistant Enterobacteriaceae (CRE) in a tertiary-care hospital in Mexico. METHODS: From September 2014 to July 2015, all CRE clinical isolates recovered during an outbreak in the Hospital Civil "Fray Antonio Alcalde" in Jalisco, Mexico were screened for antimicrobial susceptibility, carbapenemase production, carbapenemase-encoding genes, and plasmid profiles...
2017: PloS One
https://www.readbyqxmd.com/read/28636631/incidence-and-mortality-due-to-snakebite-in-the-americas
#16
Jean-Philippe Chippaux
BACKGROUND: Better knowledge of the epidemiological characteristics of snakebites could help to take measures to improve their management. The incidence and mortality of snakebites in the Americas are most often estimated from medical and scientific literature, which generally lack precision and representativeness. METHODOLOGY/PRINCIPAL FINDINGS: Authors used the notifications of snakebites treated in health centers collected by the Ministries of Health of the American countries to estimate their incidence and mortality...
June 21, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28636580/mediator-effects-of-positive-emotions-on-social-support-and-depression-among-adolescents-suffering-from-mobile-phone-addiction
#17
Menglong Li, Xia Jiang, Yujia Ren
BACKGROUND: Depression is a common mental disorder that is widely seen among adolescents suffering from mobile phone addiction. While it is well known that both positive emtions in adolescents wiotions and social support can have a positive impact by helping individuals to maintain a positive attitude, the correlation between positive emotions, social support, and depression among these adolescents remains to be investigated. This study examined the mediator effects of positive emotions on the relationship between social support and depression among adolescents suffering from mobile phone addiction...
June 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28636557/surgical-management-for-follicular-variant-of-papillary-thyroid-carcinoma
#18
Jianing Tang, Deguang Kong, Lupin Bu, Gaosong Wu
BACKGROUND AND AIMS: For most patients with follicular variant of papillary thyroid carcinoma (FVPTC), surgery is required, while the surgical management remains controversial. We aim to further understanding of treatment of FVPTC and to determine whether specific features could be identified for the decision of surgical strategy. MATERIALS AND METHODS: Data were obtained from the Surveillance, Epidemiology, and End Results (SEER) Program database during 2003 and 2013...
June 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28636543/high-grade-glioma-in-very-young-children-a-rare-and-particular-patient-population
#19
REVIEW
Moatasem El-Ayadi, Marc Ansari, Dominik Sturm, Gerrit H Gielen, Monika Warmuth-Metz, Christof M Kramm, Andre O von Bueren
In the past years, pediatric high-grade gliomas (HGG) have been the focus of several research articles and reviews, given the recent discoveries on the genetic and molecular levels pointing out a clinico-biological uniqueness of the pediatric population compared to their adult counterparts with HGG. On the other hand, there are only scarce data about HGG in very young children (below 3 years of age at diagnosis) due to their relatively low incidence. However, the few available data suggest further distinction of this very rare subgroup from older children and adults at several levels including their molecular and biological characteristics, their treatment management, as well as their outcome...
June 14, 2017: Oncotarget
https://www.readbyqxmd.com/read/28636529/bladder-cancer-and-water-disinfection-by-product-exposures-through-multiple-routes-a-population-based-case-control-study-new-england-usa
#20
Laura E Beane Freeman, Kenneth P Cantor, Dalsu Baris, John R Nuckols, Alison Johnson, Joanne S Colt, Molly Schwenn, Mary H Ward, Jay H Lubin, Richard Waddell, G Monawar Hosain, Chris Paulu, Richard McCoy, Lee E Moore, An-Tsun Huang, Nat Rothman, Margaret R Karagas, Debra T Silverman
BACKGROUND: Ingestion of disinfection byproducts has been associated with bladder cancer in multiple studies. Although associations with other routes of exposure have been suggested, epidemiologic evidence is limited. OBJECTIVES: We evaluated the relationship between bladder cancer and total, chlorinated, and brominated trihalomethanes (THMs) through various exposure routes. METHODS: In a population-based case-control study in New England ( cases; controls), we estimated lifetime exposure to THMs from ingestion, showering/bathing, and hours of swimming pool use...
June 21, 2017: Environmental Health Perspectives
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