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https://www.readbyqxmd.com/read/29156548/patient-provider-communication-and-counseling-about-gestational-weight-gain-and-physical-activity-a-qualitative-study-of-the-perceptions-and-experiences-of-latinas-pregnant-with-their-first-child
#1
Ana Cristina Lindsay, Sherrie F Wallington, Mary L Greaney, Marcia M Tavares Machado, Gabriela P De Andrade
Latina women in the United States (U.S.) are disproportionately affected by obesity and are more likely to begin pregnancy overweight and gain excessive weight during pregnancy. The prenatal care period represents a window of opportunity for women to access the healthcare system and receive preventive services, education, nutritional support, and other social services to improve pregnancy outcomes. Excessive gestational weight gain (GWG) has numerous negative short- and long-term consequences for both the mother and newborn...
November 18, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29156465/-pseudophacic-additive-lenses
#2
Fritz H Hengerer, Ina Conrad-Hengerer
Implantation of artificial intraocular lenses (IOL) after cataract removal today represents the standard of care in the field of anterior segment surgery. In refractive lens exchange cases the natural lens is replaced by an IOL to correct different types of refractive situations. In the majority of the operations the refractive result is satisfying with only few deviations from target refraction.But daily practice reveals some outliers from the intended corrections with the need for further refractive enhancements, respectively...
November 20, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29156334/applicability-evaluation-of-advanced-processes-for-elimination-of-neurophysiological-activity-of-antidepressant-fluoxetine
#3
László Szabó, Viktória Mile, Dóra J Kiss, Krisztina Kovács, Tamás Földes, Tamás Németh, Tünde Tóth, Renáta Homlok, György T Balogh, Erzsébet Takács, László Wojnárovits
Presence of the antidepressant fluoxetine in different water bodies has raised significant concerns due to its detrimental effects on non-targeted organisms, especially on fish. When seeking for an appropriate technology able to remove fluoxetine residue from a complex water matrix, special attention needs to be paid to the elimination of the neurophysiological activity that eventually lies behind the noxious effects of the parent compound. Our aim was to probe the applicability of advanced oxidation techniques for this purpose using in situ generated free radical system based on OH-initiated peroxyl radical-mediated processes...
November 11, 2017: Chemosphere
https://www.readbyqxmd.com/read/29155283/comparative-analysis-of-media-effects-on-human-induced-pluripotent-stem-cell-derived-cardiomyocytes-in-proarrhythmia-risk-assessment
#4
Derek Schocken, Jayna Stohlman, Jose Vicente, Dulciana Chan, Dakshesh Patel, Murali Krishna Matta, Vikram Patel, Mathew Brock, Daniel Millard, James Ross, David G Strauss, Ksenia Blinova
INTRODUCTION: Cardiotoxicity assessment using human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) forms a key component of the Comprehensive in Vitro Proarrhythmia Assay (CiPA). A potentially impactful factor on iPSC-CM testing is the presence of serum in the experimental media. Generally, serum-free media is used to most accurately reproduce "free" drug concentration. However, caution is needed; drug solubility and cardiomyocyte electrophysiology could be affected by media formulation, potentially impacting interpretation of drug-induced effects...
November 16, 2017: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/29155095/behavioral-and-neural-mechanisms-by-which-prior-experience-impacts-subsequent-learning
#5
Ryan G Parsons
Memory is often thought about in terms of its ability to recollect and store information about the past, but its function likely rests with the fact that it permits adaptation to ongoing and future experience. Thus, the brain circuitry that encodes memory must act as if stored information is likely to be modified by subsequent experience. Considerable progress has been made in identifying the behavioral and neural mechanisms supporting the acquisition and consolidation of memories, but this knowledge comes largely from studies in laboratory animals in which the training experience is presented in isolation from prior experimentally-controlled events...
November 16, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29155018/emerging-infections-are-an-increasingly-important-topic
#6
REVIEW
Eskild Petersen, Nicola Petrosillo, Marion Koopmans
OBJECTIVES: This paper review trends in emerging infections and the need for increased clinical and laboratory surveillance. METHODS: Factors that contributed to the emergence of recent outbreaks have been reviewed. Known, major outbreaks over the past two decades were reviewed. RESULTS: We identified at least four major drivers of emergent infections: i. increasing density of the human population; ii. stress from farmland expansion on the environment; iii...
November 15, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29154748/cdc-safety-training-course-for-ebola-virus-disease-healthcare-workers
#7
Rupa Narra, Jeremy Sobel, Catherine Piper, Deborah Gould, Nahid Bhadelia, Mary Dott, Anthony Fiore, William A Fischer, Mary Jo Frawley, Patricia M Griffin, Douglas Hamilton, Barbara Mahon, Satish K Pillai, Emily F Veltus, Robert Tauxe, Michael Jhung
Response to sudden epidemic infectious disease emergencies can demand intensive and specialized training, as demonstrated in 2014 when Ebola virus disease (EVD) rapidly spread throughout West Africa. The medical community quickly became overwhelmed because of limited staff, supplies, and Ebola treatment units (ETUs). Because a mechanism to rapidly increase trained healthcare workers was needed, the US Centers for Disease Control and Prevention developed and implemented an introductory EVD safety training course to prepare US healthcare workers to work in West Africa ETUs...
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29154210/clinical-pharmacokinetic-pharmacodynamic-analyses-a-critical-element-for-developing-antibacterial-agents
#8
REVIEW
Sujata M Bhavnani, Jeffrey P Hammel
In the current of era of developing antibacterial agents, including those for unmet medical need, Sponsors are required to submit a robust pre-clinical pharmacokinetic-pharmacodynamic (PK-PD) data package in exchange for limited clinical data. However, the clinical data package also needs to be as robust as possible. The clinical data package needs to include the Phase 1 pharmacokinetic (PK) studies conducted in the target patient populations and special populations. Additionally, PK data need to be collected from all patients enrolled in the pivotal trial(s)...
November 16, 2017: Current Opinion in Pharmacology
https://www.readbyqxmd.com/read/29153519/invited-review-practical-feeding-management-recommendations-to-mitigate-the-risk-of-subacute-ruminal-acidosis-in-dairy-cattle
#9
E Humer, R M Petri, J R Aschenbach, B J Bradford, G B Penner, M Tafaj, K-H Südekum, Q Zebeli
Rumen health is of vital importance in ensuring healthy and efficient dairy cattle production. Current feeding programs for cattle recommend concentrate-rich diets to meet the high nutritional needs of cows during lactation and enhance cost-efficiency. These diets, however, can impair rumen health. The term "subacute ruminal acidosis" (SARA) is often used as a synonym for poor rumen health. In this review, we first describe the physiological demands of cattle for dietary physically effective fiber. We also provide background information on the importance of enhancing salivary secretions and short-chain fatty acid absorption across the stratified squamous epithelium of the rumen; thus, preventing the disruption of the ruminal acid-base balance, a process that paves the way for acidification of the rumen...
November 15, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29152714/scaffolding-as-a-key-role-for-teaching-assistants-perceptions-of-their-pedagogical-strategies
#10
David Bowles, Julie Radford, Ioanna Bakopoulou
BACKGROUND: Inclusive education policies have led to a worldwide increase in the number of teaching assistants (TAs) working in mainstream schools. TAs have a large amount of responsibility for supporting children with special educational needs and disabilities (SEND), a role which by default has become instructional in practice, and for which training and preparation are rarely adequate. While there is some research into the nature of TAs' interactions with pupils and the strategies they use which are helpful for children's learning, TAs' perspectives on their own classroom practice have yet to be explored...
November 19, 2017: British Journal of Educational Psychology
https://www.readbyqxmd.com/read/29152434/characterization-of-eyeball-loss-in-four-cities-of-colombia
#11
F Hernán Moreno-Caviedes, Nórida Velez Cuellar, Margarita Caicedo Zapata, Gabriel Triana Reina, Azucena Sánchez
PURPOSE: Describe the socio-demographic characteristics of anophthalmic patients examined at specialized centers of four cities in Colombia to know the different causes of eyeball loss. METHOD: A transversal retrospective study was done of 511 medical records from the specialized practices of four cities in Colombia. Socio-demographic data of patients who were seen between January 2011 and December 2013 were compiled. SOFA Statistics software v1.4.6 was used for this analysis...
September 11, 2017: Curēus
https://www.readbyqxmd.com/read/29152165/specificity-of-executive-function-and-theory-of-mind-performance-in-relation-to-attention-deficit-hyperactivity-symptoms-in-autism-spectrum-disorders
#12
Steve Lukito, Catherine R G Jones, Andrew Pickles, Gillian Baird, Francesca Happé, Tony Charman, Emily Simonoff
Background: Individuals with autism spectrum disorder (ASD) frequently demonstrate symptoms of attention-deficit/hyperactivity disorder (ADHD). Previous findings in children with ASD have suggested that these symptoms are associated with an impairment in executive function (EF) abilities. However, studies rarely considered this association within a single framework that controls for other related factors such as Theory of Mind (ToM) abilities and ASD symptoms. Methods: We used structural equation modeling to explore the relations among EF, ToM, and symptoms of ASD and ADHD, using data from a population-based sample of 100 adolescents with ASD and full-scale IQ ≥ 50 (the Special Needs and Autism Project (SNAP) cohort)...
2017: Molecular Autism
https://www.readbyqxmd.com/read/29152160/traumatized-refugees-identifying-needs-and-facing-challenges-for-mental-health-care
#13
EDITORIAL
Christine Knaevelsrud, Nadine Stammel, Miranda Olff
In the past few years the number of refugees worldwide has increased dramatically. Many of them were traumatized in their homelands due to violent conflict or persecution, as well as during their flight, and are confronted with ongoing stressors in the exile countries. In order to contribute to enhancing the clinical knowledge, this special issue of the European Journal of Psychotraumatology focuses on traumatized refugees. It includes three review articles as well as four original articles on the mental health burden, screening instruments and interventions in different groups of refugees...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29151820/name-it-store-it-protect-it-a-systems-approach-to-managing-data-in-research-core-facilities
#14
REVIEW
Matthew DeVries, Michael Fenchel, R E Fogarty, Byong-Do Kim, Daniel Timmons, A Nicole White
As the capabilities of technology increase, so do the production of data and the need for data management. The need for data storage at many academic institutions is increasing exponentially. Technology is expanding rapidly, and institutions are recognizing the need to incorporate data management that can be available for future data sharing as a critical component of institutional services. The establishment of a process to manage the surge in data storage is complex and often hindered by not having a plan...
November 2, 2017: Journal of Biomolecular Techniques: JBT
https://www.readbyqxmd.com/read/29151362/elimination-of-schistosomiasis-the-tools-required
#15
REVIEW
Robert Bergquist, Xiao-Nong Zhou, David Rollinson, Jutta Reinhard-Rupp, Katharina Klohe
BACKGROUND: Historically, the target in the schistosomiasis control has shifted from infection to morbidity, then back to infection, but now as a public health problem, before moving on to transmission control. Currently, all endemic countries are encouraged to increase control efforts and move towards elimination as required by the World Health Organization (WHO) roadmap for the global control of the neglected tropical diseases (NTDs) and the WHA65.21 resolution issued by the World Health Assembly...
November 20, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29151344/computation-of-hemagglutinin-free-energy-difference-by-the-confinement-method
#16
Sander Boonstra, Patrick R Onck, Erik Van der Giessen
Hemagglutinin (HA) mediates membrane fusion, a crucial step during influenza virus cell entry. How many HAs are needed for this process is still subject to debate. To aid in this discussion, the confinement free energy method was used to calculate the conformational free energy difference between the extended intermediate and postfusion state of HA. Special care was taken to comply with general guidelines for free energy calculations, thereby obtaining convergence and demonstrating reliability of the results...
November 20, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29150170/evaluating-the-content-and-development-of-decision-aid-tools-for-the-management-of-menopause-a-scoping-review
#17
REVIEW
Tasneem Siyam, Humirah Sultani, Sue Ross, Trish Chatterley, Nese Yuksel
OBJECTIVE: Decision-making during menopause (especially surgical menopause) can be complex given the variability in risk-benefit perceptions of menopausal treatments. Decision aid tools (DATs) help women participate in decision-making about options. Our objective is to identify and evaluate the content and development of DATs for managing menopause, with a special focus on surgical menopause. METHODS: We systematically searched electronic databases, including MEDLINE and EMBASE, from inception to March 2017 for relevant records...
December 2017: Maturitas
https://www.readbyqxmd.com/read/29149359/-preclinical-and-intrahospital-management-of-mass-casualties-and-terrorist-incidents
#18
REVIEW
A Franke, D Bieler, B Friemert, E Kollig, S Flohe
Due to the recent terrorist attacks in Paris, Brussels, Ansbach, Munich, Berlin and more recently Manchester and London, terrorism is realized as a present threat to our society and social life, as well as a challenge for the health care system. Without fueling anxiety, there is a need for sensitization to this subject and to familiarize all concerned with the special kind of terrorist attack-related injuries, the operational priorities and tactics and the individual basic principles of preclinical and hospital care...
October 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29148565/tobacco-cessation-interventions-for-young-people
#19
REVIEW
Thomas R Fanshawe, William Halliwell, Nicola Lindson, Paul Aveyard, Jonathan Livingstone-Banks, Jamie Hartmann-Boyce
BACKGROUND: Most tobacco control programmes for adolescents are based around prevention of uptake, but teenage smoking is still common. It is unclear if interventions that are effective for adults can also help adolescents to quit. This is the update of a Cochrane Review first published in 2006. OBJECTIVES: To evaluate the effectiveness of strategies that help young people to stop smoking tobacco. SEARCH METHODS: We searched the Cochrane Tobacco Addiction Group's Specialized Register in June 2017...
November 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29148562/recurrence-of-reported-cdh23-mutations-causing-dfnb12-in-a-special-cohort-of-south-indian-hearing-impaired-assortative-mating-families-an-evaluation
#20
Paridhy Vanniya S, Jayasankaran Chandru, Amritkumar Pavithra, Justin Margret Jeffrey, Murugesan Kalaimathi, Rajagopalan Ramakrishnan, Natarajan P Karthikeyen, Srisailapathy C R Srikumari
Mutations in CDH23 are known to cause autosomal-recessive nonsyndromic hearing loss (DFNB12). Until now, there was only one study describing its frequency in Indian population. We screened for CDH23 mutations to identify prevalent and recurring mutations among South Indian assortative mating hearing-impaired individuals who were identified as non-DFNB1 (GJB2 and GJB6). Whole-exome sequencing was performed in individuals found to be heterozygous for CDH23 to determine whether there was a second pathogenic allele...
November 17, 2017: Annals of Human Genetics
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