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https://www.readbyqxmd.com/read/28350790/use-of-common-analgesic-medications-and-ovarian-cancer-survival-results-from-a-pooled-analysis-in-the-ovarian-cancer-association-consortium
#1
Suzanne C Dixon, Christina M Nagle, Nicolas Wentzensen, Britton Trabert, Alicia Beeghly-Fadiel, Joellen M Schildkraut, Kirsten B Moysich, Anna deFazio, Harvey A Risch, Mary Anne Rossing, Jennifer A Doherty, Kristine G Wicklund, Marc T Goodman, Francesmary Modugno, Roberta B Ness, Robert P Edwards, Allan Jensen, Susanne K Kjær, Estrid Høgdall, Andrew Berchuck, Daniel W Cramer, Kathryn L Terry, Elizabeth M Poole, Elisa V Bandera, Lisa E Paddock, Hoda Anton-Culver, Argyrios Ziogas, Usha Menon, Simon A Gayther, Susan J Ramus, Aleksandra Gentry-Maharaj, Celeste Leigh Pearce, Anna H Wu, Malcolm C Pike, Penelope M Webb
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been associated with improved survival in some cancers, but evidence for ovarian cancer is limited. METHODS: Pooling individual-level data from 12 Ovarian Cancer Association Consortium studies, we evaluated the association between self-reported, pre-diagnosis use of common analgesics and overall/progression-free/disease-specific survival among 7694 women with invasive epithelial ovarian cancer (4273 deaths)...
March 28, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28346131/lack-of-diversity-in-personal-health-record-evaluations-with-older-adult-participants-a-systematic-review-of-literature
#2
Laura Kneale, George Demiris
BACKGROUND: Older adults are not adopting personal health records (PHRs) at the same rates as other adult populations. Disparities in adoption rates are also reported in older adult subgroups. The variability in adoption may be because PHRs are not designed to meet older adult users. OBJECTIVE: We analyzed PHR evaluation studies to examine the characteristics and perspectives of older adult study participants to identify their self-reported needs. METHOD: We searched Medline, CINAHL, PsycINFO, and Embase for PHR evaluation studies that involved older adult participants...
January 15, 2017: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/28334951/community-participation-in-research-from-resource-constrained-countries-a-scoping-review
#3
Michelle Brear, Karin Hammarberg, Jane Fisher
Participatory health research (PHR) involves equitable community participation in all aspects of the research process. It is a potentially beneficial approach to research in resource-constrained countries. Measuring participation in specific activities and aspects is necessary for understanding the community and research-related benefits of PHR. The aims of this scoping review were to: develop a measure of lay-community participation in aspects and activities of PHR in resource-constrained countries; and use the measure to assess the nature and extent of reported participation...
March 18, 2017: Health Promotion International
https://www.readbyqxmd.com/read/28325112/potential-of-personal-health-record-portals-in-the-care-of-individuals-with-spinal-cord-injuries-and-disorders-provider-perspectives
#4
Jennifer N Hill, Bridget M Smith, Frances M Weaver, Kim M Nazi, Florian P Thomas, Barry Goldstein, Timothy P Hogan
CONTEXT/OBJECTIVE: Although personal health record (PHR) portals are designed for patients, healthcare providers are a key influence in how patients use their features and realize benefits from them. A few studies have examined provider attitudes toward PHR portals, but none have focused on those who care for individuals with spinal cord injuries and disorders (SCI/D). We characterize SCI/D provider perspectives of PHR portals, including perceived advantages and disadvantages of PHR portal use in SCI/D care...
March 21, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28303255/active-use-of-electronic-health-records-ehrs-and-personal-health-records-phrs-for-epidemiologic-research-sample-representativeness-and-nonresponse-bias-in-a-study-of-women-during-pregnancy
#5
Julie K Bower, Claire E Bollinger, Randi E Foraker, Darryl B Hood, Abigail B Shoben, Albert M Lai
INTRODUCTION: With the growing use of electronic medical records, electronic health records (EHRs), and personal health records (PHRs) for health care delivery, new opportunities have arisen for population health researchers. Our objective was to characterize PHR users and examine sample representativeness and nonresponse bias in a study of pregnant women recruited via the PHR. DESIGN: Demographic characteristics were examined for PHR users and nonusers. Enrolled study participants (responders, n=187) were then compared with nonresponders and a representative sample of the target population...
2017: EGEMS
https://www.readbyqxmd.com/read/28294365/prevalence-of-prenatal-alcohol-exposure-in-the-state-of-texas-as-assessed-by-phosphatidylethanol-in-newborn-dried-blood-spot-specimens
#6
Ludmila N Bakhireva, Janet Sharkis, Shikhar Shrestha, Tristan J Miranda-Sohrabji, Sonnie Williams, Rajesh C Miranda
BACKGROUND: While 2-5% of school-aged children in the U.S. are estimated to be affected by Fetal Alcohol Spectrum Disorders (FASD), the prevalence of prenatal alcohol exposure (PAE) might be substantially under-reported. Our objective was to systematically estimate the prevalence of PAE in Texas by measuring a direct ethanol metabolite, phosphatidylethanol (PEth), in 1,000 infant residual dried blood spots (irDBS) in the Texas Newborn Screening Repository. METHODS: All Public Health Regions were represented proportional to their 2014 birth rate (~0...
March 13, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28274313/-establishment-of-esophageal-squamous-carcinoma-cell-lines-stably-over-expressing-llgl2
#7
Qiong Hu, Fu'an Xie, Xiaoqian Hong, Kuancan Liu
Objective To prepare a lentiviral vector expressing LLGL2 and establish KYSE450 and TE-1 cell lines for the stable expression of LLGL2. Methods The full-length LLGL2 sequence was amplified by high-fidelity PCR, and then it was inserted into pCDH-CMV-IRES-GFP-EF1-Puro vectors. The recombinant plasmid was confirmed by double enzyme digestion and sequencing. After co-infection of pCDH-CMV-LLGL2-IRES- GFP-EF1-Puro with vesicular stomatitis virus glycoprotein (VSVG) and PHR into HEK293T cells, the lentivirus was harvested and used for infecting esophageal squamous cell carcinoma cell lines including KYSE450 and TE-1 cells...
March 2017: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://www.readbyqxmd.com/read/28254419/human-papillomavirus-infection-and-cervical-lesions-in-hiv-infected-women-on-antiretroviral-treatment-in-thailand
#8
Tristan Delory, Nicole Ngo-Giang-Huong, Samreung Rangdaeng, Nantasak Chotivanich, Aram Limtrakul, Chaiwat Putiyanun, Pornnapa Suriyachai, Wanmanee Matanasarawut, Tapnarong Jarupanich, Prateung Liampongsabuddhi, Isabelle Heard, Gonzague Jourdain, Marc Lallemant, Sophie Le Coeur
OBJECTIVES: To estimate the prevalence and factors associated with Human Papillomavirus (HPV) infection, HPV genotypes and cytological/histological high-grade (HSIL+/CIN2+) lesions. METHODS: We conducted a cross-sectional study within a prospective cohort of HIV-infected women on combination antiretroviral therapy (cART). Cervical specimens were collected for cytology and HPV genotyping (Papillocheck(®)). Any women with High-Risk-HPV (HR-HPV), and/or potentially HR-HPV (pHR-HPV) and/or ASC-US or higher (ASC-US+) lesions were referred for colposcopy...
February 28, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28236696/effect-of-ethyl-ester-l-lysine-triisocyanate-addition-to-produce-reactive-pla-pcl-bio-polyester-blends-for-biomedical-applications
#9
Annamaria Visco, Davide Nocita, Alberto Giamporcaro, Sara Ronca, Giuseppe Forte, Alessandro Pistone, Claudia Espro
We report in this paper the effects of Ethyl Ester L-Lysine Triisocyanate (LTI) on the physical-mechanical properties of Poly(lactide)/Poly(ε-caprolactone) (PLA/PCL) polyesters blends. The PLA/PCL ratios considered were 20/80, 50/50 and 80/20 (wt/wt %) and LTI was added in amounts of 0.0-0.5-1.0 phr. PLA and PCL reacted with LTI during processing in a Brabender twin screw internal mixer to produce block copolymers in-situ. The resulting blends have been characterized by torque measurements, uniaxial tensile tests, Differential Scanning Calorimeter, contact angle measurements with a Phosphate Buffered Saline (PBS) solution, ATR analysis and morphological SEM observations...
February 16, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28223814/the-dynamic-relationship-between-emotional-and-physical-states-an-observational-study-of-personal-health-records
#10
Ye-Seul Lee, Won-Mo Jung, Hyunchul Jang, Sanghyun Kim, Sun-Yong Chung, Younbyoung Chae
OBJECTIVES: Recently, there has been increasing interest in preventing and managing diseases both inside and outside medical institutions, and these concerns have supported the development of the individual Personal Health Record (PHR). Thus, the current study created a mobile platform called "Mind Mirror" to evaluate psychological and physical conditions and investigated whether PHRs would be a useful tool for assessment of the dynamic relationship between the emotional and physical conditions of an individual...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28202428/patient-use-of-electronic-prescription-refill-and-secure-messaging-and-its-association-with-undetectable-hiv-viral-load-a-retrospective-cohort-study
#11
D Keith McInnes, Stephanie L Shimada, Amanda M Midboe, Kim M Nazi, Shibei Zhao, Justina Wu, Casey M Garvey, Thomas K Houston
BACKGROUND: Electronic personal health records (PHRs) can support patient self-management of chronic conditions. Managing human immunodeficiency virus (HIV) viral load, through taking antiretroviral therapy (ART) is crucial to long term survival of persons with HIV. Many persons with HIV have difficulty adhering to their ART over long periods of time. PHRs contribute to chronic disease self-care and may help persons with HIV remain adherent to ART. Proportionally veterans with HIV are among the most active users of the US Department of Veterans Affairs (VA) PHR, called My HealtheVet...
February 15, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28186028/deriving-a-set-of-privacy-specific-heuristics-for-the-assessment-of-phrs-personal-health-records
#12
Riccardo F Furano, Andre Kushniruk, Jeff Barnett
With the emergence of personal health record (PHR) platforms becoming more widely available, this research focused on the development of privacy heuristics to assess PHRs regarding privacy. Existing sets of heuristics are typically not application specific and do not address patient-centric privacy as a main concern prior to undergoing PHR procurement. A set of privacy specific heuristics were developed based on a scoping review of the literature. An internet-based commercially available, vendor specific PHR application was evaluated using the derived set of privacy specific heuristics...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28186019/designing-personal-health-record-technology-for-shared-decision-making
#13
Selena Davis, Abdul Roudsari, Karen L Courtney
Engaging patients in the self-management decision-making provides opportunities for positive health outcomes. The process of shared decision-making (SDM) is touted as the pinnacle of patient-centred care, yet it has been difficult to implement in practice. Access to tools resulting from the integration of all health data and clinical evidence, and an ease of communications with care providers are needed to engage patients in self management decision-making. Personal health record (PHR) technology is a promising approach for overcoming such barriers...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28177702/modulation-of-mitochondrial-biomarkers-by-intermittent-hypobaric-hypoxia-and-aerobic-exercise-after-eccentric-exercise-in-trained-rats
#14
David Rizo-Roca, Juan Gabriel Ríos-Kristjánsson, Cristian Núñez-Espinosa, Estela Santos-Alves, José Magalhães, António Ascensão, Teresa Pagès, Ginés Viscor, Joan Ramon Torrella
Unaccustomed eccentric contractions induce muscle damage, calcium homeostasis disruption and mitochondrial alterations. Since exercise and hypoxia are known to modulate mitochondrial function, we aimed to analyze the effects on eccentric exercise-induced muscle damage (EEIMD), in trained rats, of two recovery protocols based on: 1) intermittent hypobaric hypoxia (IHH) and 2) IHH followed by exercise. The expression of biomarkers related to mitochondrial biogenesis, dynamics, oxidative stress and bioenergetics was evaluated...
February 2, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28154555/key-impact-of-an-uncommon-plasmid-on-bacillus-amyloliquefaciens-subsp-plantarum-s499-developmental-traits-and-lipopeptide-production
#15
Giulia Molinatto, Laurent Franzil, Sébastien Steels, Gerardo Puopolo, Ilaria Pertot, Marc Ongena
The rhizobacterium Bacillus amyloliquefaciens subsp. plantarum S499 (S499) is particularly efficient in terms of the production of cyclic lipopeptides, which are responsible for the high level of plant disease protection provided by this strain. Sequencing of the S499 genome has highlighted genetic differences and similarities with the closely related rhizobacterium B. amyloliquefaciens subsp. plantarum FZB42 (FZB42). More specifically, a rare 8008 bp plasmid (pS499) harboring a rap-phr cassette constitutes a major distinctive element between S499 and FZB42...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28121135/dielectric-elastomer-generator-with-improved-energy-density-and-conversion-efficiency-based-on-polyurethane-composites
#16
Guoling Yin, Yu Yang, Feilong Song, Christophe Renard, Zhi-Min Dang, Chang-Yong Shi, Dongrui Wang
Dielectric elastomer generators (DEGs), which follow the physics of variable capacitors and harvest electric energy from mechanical work, have attracted intensive attention over the past decade. The lack of ideal dielectric elastomers, after nearly two decades of research, has become the bottleneck for DEGs' practical applications. Here, we fabricated a series of polyurethane-based ternary composites and estimated their potential as DEGs to harvest electric energy for the first time. Thermoplastic polyurethane (PU) with high relative permittivity (∼8) was chosen as the elastic matrix...
February 6, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28094912/strong-strain-sensing-performance-of-natural-rubber-nanocomposites
#17
Tamil Selvan Natarajan, Subramani Bhagavatheswaran Eshwaran, Klaus Werner Stöckelhuber, Sven Wießner, Petra Pötschke, Gert Heinrich, Amit Das
A detail study concerning the strain (tensile) dependent electrical conductivity of elastomeric composites is reported in this present paper. Multiwall carbon nanotubes (CNT), conducting carbon black (CB), and their combinations were considered as conducting filler in cross-linked natural rubber matrix. The loadings of the fillers were considered from 3 to 11 phr (filler concentration close to their percolation threshold). Without hindering the elastic nature of the composite (reversible stretchability up to several 100%), the change of relative resistance, ΔR/R0 (ΔR is the change in the resistance with respect to strain and R0 is the initial resistance of the sample) of the CB filled composites was found to be as much as ∼1300 at around 120% elongation...
January 30, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28070215/multiple-hpv-infections-in-female-sex-workers-in-western-kenya-implications-for-prophylactic-vaccines-within-this-sub-population
#18
Sonia Menon, Davy van den Broeck, Rodolfo Rossi, Emilomo Ogbe, Hillary Mabeya
BACKGROUND: Whilst the imputed role of High Risk (HR) HPV infection in the development of cervical lesions and cancer has been established, the high number of HPV genotypes that Female Sex workers (FSW) harbour warrants that the synergistic effects of potential HR (pHR) and HR HPV genotypes be elucidated to assess the potential impact of prophylactic vaccines. This population in Kenya also harbours a number of other vaginal infections and STIs, including bacterial vaginosis (BV), trichomonas vaginalis (TV) and candida spp...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28063166/cigarette-smoking-is-associated-with-adverse-survival-among-women-with-ovarian-cancer-results-from-a-pooled-analysis-of-19-studies
#19
Camilla Praestegaard, Allan Jensen, Signe M Jensen, Thor S S Nielsen, Penelope M Webb, Christina M Nagle, Anna DeFazio, Estrid Høgdall, Mary Anne Rossing, Jennifer A Doherty, Kristine G Wicklund, Marc T Goodman, Francesmary Modugno, Kirsten Moysich, Roberta B Ness, Robert Edwards, Keitaro Matsuo, Satoyo Hosono, Ellen L Goode, Stacey J Winham, Brooke L Fridley, Daniel W Cramer, Kathryn L Terry, Joellen M Schildkraut, Andrew Berchuck, Elisa V Bandera, Lisa E Paddock, Leon F Massuger, Nicolas Wentzensen, Paul Pharoah, Honglin Song, Alice Whittemore, Valerie McGuire, Weiva Sieh, Joseph Rothstein, Hoda Anton-Culver, Argyrios Ziogas, Usha Menon, Simon A Gayther, Susan J Ramus, Alexandra Gentry-Maharaj, Anna H Wu, Celeste L Pearce, Malcolm Pike, Alice W Lee, Rebecca Sutphen, Jenny Chang-Claude, Harvey A Risch, Susanne K Kjaer
Cigarette smoking is associated with an increased risk of developing mucinous ovarian tumours but whether it is associated with ovarian cancer survival overall or for the different histotypes is unestablished. Furthermore, it is unknown whether the association between cigarette smoking and survival differs according to strata of ovarian cancer stage at diagnosis. In a large pooled analysis, we evaluated the association between various measures of cigarette smoking and survival among women with epithelial ovarian cancer...
January 7, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28062391/personal-health-records-a-systematic-literature-review
#20
REVIEW
Alex Roehrs, Cristiano André da Costa, Rodrigo da Rosa Righi, Kleinner Silva Farias de Oliveira
BACKGROUND: Information and communication technology (ICT) has transformed the health care field worldwide. One of the main drivers of this change is the electronic health record (EHR). However, there are still open issues and challenges because the EHR usually reflects the partial view of a health care provider without the ability for patients to control or interact with their data. Furthermore, with the growth of mobile and ubiquitous computing, the number of records regarding personal health is increasing exponentially...
January 6, 2017: Journal of Medical Internet Research
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