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https://www.readbyqxmd.com/read/27891621/animal-cryptochromes-divergent-roles-in-light-perception-circadian-timekeeping-and-beyond
#1
Alicia K Michael, Jennifer L Fribourgh, Russell N Van Gelder, Carrie L Partch
Cryptochromes are evolutionarily related to the light-dependent DNA repair enzyme photolyase, serving as major regulators of circadian rhythms in insects and vertebrate animals. There are two types of cryptochromes in the animal kingdom: Drosophila-like CRYs that act as non-visual photopigments linking circadian rhythms to the environmental light/dark cycle, and vertebrate-like CRYs that do not appear to sense light directly, but control the generation of circadian rhythms by acting as transcriptional repressors...
November 28, 2016: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/27884871/simultaneous-liquid-chromatographic-determination-of-ebastine-with-two-sympathomimetic-drugs-using-a-monolithic-column
#2
F Ibrahim, M E K Wahba
Ebastine (EBS) has been assayed in its laboratory-prepared co-formulated tablets with either pseudoephedrine hydrochloride (PSU) or phenylephrine hydrochloride (PHR) using isocratic reversed-phase chromatography. Separation was conducted using a 50 mm × 4.6 mm i.d., Chromolith(®) SpeedROD RP-18 end-capped column at ambient temperature. A mobile phase composed of water:acetonitrile in a ratio of 25:75 having a pH of 3.2, has been utilized at 1 mL/min with UV detection at 254 nm for both EBS and PSU and 274 nm for PHR which in turn increased the sensitivity of the proposed method significantly...
November 24, 2016: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/27883135/synthesis-of-mno2-nanoparticles-and-their-effective-utilization-as-uv-protectors-for-outdoor-high-voltage-polymeric-insulators-used-in-power-transmission-lines
#3
Dipankar Ghosh, Subhendu Bhandari, Dipak Khastgir
Polymeric outdoor insulators derived from polydimethyl siloxane (PDMS) are replacing conventional ceramic insulators in high voltage power transmission lines because of their improved electrical, mechanical and hydrophobic performance. Major impediments like failure of polymeric insulators due to natural aging by UV radiation from sunlight and electrical tracking have limited their usage. Herein, it is demonstrated about the usage of manganese dioxide based nanoparticles as an effective agent to prevent the UV accelerated aging of polymeric insulators...
November 24, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27881987/microscopic-and-molecular-characterization-of-the-prehaustorial-resistance-against-wheat-leaf-rust-puccinia-triticina-in-einkorn-triticum-monococcum
#4
Albrecht Serfling, Sven E Templer, Peter Winter, Frank Ordon
Puccinia triticina f. sp. tritici (Eriks.), the causal agent of leaf rust, causes substantial yield losses in wheat production. In wheat many major leaf rust resistance genes have been overcome by virulent races. In contrast, the prehaustorial resistance (phr) against wheat leaf rust detected in the diploid wheat Einkorn (Triticum monoccocum var. monococcum) accession PI272560 confers race-independent resistance against isolates virulent on accessions harboring resistance genes located on the A-genome of Triticum aestivum...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27864885/phylogenetic-and-functional-classification-of-the-photolyase-cryptochrome-family
#5
Nuri Ozturk
The Photolyase/Cryptochrome (PHR/CRY) family is a large group of proteins with similar structure and but very diverge functions such as in DNA repair, circadian clock resetting, and regulation of transcription. As a result of advances in the biochemistry of the CRY/PHR family and identification of new members, several adjustments have been made to the classification of this protein family. For example, a new class of PHRs, Class III, has been proposed. Furthermore, CRYs have been suggested to function as photosensory proteins in the primordial eye of sponge larvae...
November 19, 2016: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/27847722/physiological-responses-during-the-lower-body-positive-pressure-supported-treadmill-test
#6
Ka-Young Lee, Jae-Young Han, Ji-Hyun Kim, Dong-Ju Kim, In-Sung Choi
OBJECTIVE: To quantify changes in cardiopulmonary function using a lower body positive pressure supported (LBPPS) treadmill during the exercise tolerance test (ETT) in healthy subjects before applying the LBPPS treadmill in patients with gait problems. METHODS: We evaluated 30 healthy subjects who were able to walk independently. The ETT was performed using the Modified Bruce Protocol (stages 1-5) at four levels (0%, 40%, 60%, and 80%) of LBPPS. The time interval at each level of the LBPPS treadmill test was 20 minutes to recover to baseline status...
October 2016: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/27834182/marked-sex-differences-in-all-cause-mortality-on-antiretroviral-therapy-in-low-and-middle-income-countries-a-systematic-review-and-meta-analysis
#7
REVIEW
Sarah W Beckham, Chris Beyrer, Peter Luckow, Meg Doherty, Eyerusalem K Negussie, Stefan D Baral
INTRODUCTION: While women and girls are disproportionately at risk of HIV acquisition, particularly in low- and middle-income countries (LMIC), globally men and women comprise similar proportions of people living with HIV who are eligible for antiretroviral therapy. However, men represent only approximately 41% of those receiving antiretroviral therapy globally. There has been limited study of men's outcomes in treatment programmes, despite data suggesting that men living with HIV and engaged in treatment programmes have higher mortality rates...
2016: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/27809976/feeding-horses-with-industrially-manufactured-pellets-with-fungal-spores-to-promote-nematode-integrated-control
#8
José Ángel Hernández, Fabián Leonardo Arroyo, José Suárez, Cristiana Filipa Cazapal-Monteiro, Ángel Romasanta, María Eugenia López-Arellano, José Pedreira, Luis Manuel Madeira de Carvalho, Rita Sánchez-Andrade, María Sol Arias, Pedro Mendoza de Gives, Adolfo Paz-Silva
The usefulness of pellets industrially manufactured with spores of parasiticide fungi as a contribution to integrated nematode control was assessed in grazing horses throughout sixteen months. Two groups of 7 Pura Raza Galega autochthonous horses (G-T and G-P) were dewormed pour-on (1mg Ivermectin/kg bw) at the beginning of the trial, and other group (G-C) remained untreated. The G-P was provided daily with commercial pellets to which was added a mixture of fungal spores during the industrial manufacturing (2×10(6) spores of Mucor circinelloides and same dose of Duddingtonia flagrans/kg), and G-T and G-C received pellets without spores...
October 15, 2016: Veterinary Parasitology
https://www.readbyqxmd.com/read/27798390/smartphone-use-among-postpartum-women-and-implications-for-personal-health-record-utilization
#9
Nadira Fernandez, Danis J Copenhaver, David K Vawdrey, Helen Kotchoubey, Melissa S Stockwell
Personal health records (PHRs) have the potential to improve incomplete health records. However, internet access through traditional methods may be limited for populations most at risk for fragmented care. A convenience sample of postpartum women at a community hospital and tertiary-care academic center in New York City completed a self-administered survey. Most (75.2%, n = 200) women approached participated. The majority (70.0%) were Latina, 53.5% were Spanish speakers, 23.4% were uninsured, and 41.6% were publicly insured...
October 18, 2016: Clinical Pediatrics
https://www.readbyqxmd.com/read/27765844/intermittent-hypobaric-hypoxia-combined-with-aerobic-exercise-improves-muscle-morphofunctional-recovery-after-eccentric-exercise-to-exhaustion-in-trained-rats
#10
David Rizo-Roca, Juan Gabriel Ríos-Kristjánsson, Cristian Núñez-Espinosa, Estela Santos-Alves, Ines O Goncalves, Jose Magalhaes, Antonio A Ascensao, Teresa Pagès, Ginés Viscor, Joan Ramon Torrella
Unaccustomed eccentric exercise leads to muscle morphological and functional alterations, including microvasculature damage, the repair of which is modulated by hypoxia. Here we present the effects of intermittent hypobaric hypoxia and exercise on recovery from eccentric-induced muscle damage (EEIMD). Soleus muscles from trained rats were excised pre- (CTRL) and 1, 3, 7 and 14 days after a double session of EEIMD protocol. A recovery treatment consisting of one of the following protocols was applied one day after the EEIMD: passive normobaric recovery (PNR), a 4-hour daily exposure to passive hypobaric hypoxia at 4000m (PHR) or hypobaric hypoxia exposure followed by aerobic exercise (AHR)...
October 20, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27764092/epidemiology-of-hpv-genotypes-among-hiv-positive-women-in-kenya-a-systematic-review-and-meta-analysis
#11
Sonia Menon, Aibibula Wusiman, Marie Claude Boily, Mbabazi Kariisa, Hillary Mabeya, Stanley Luchters, Frode Forland, Rodolfo Rossi, Steven Callens, Davy Vanden Broeck
BACKGROUND: There is a scarcity of data on the distribution of human papillomavirus (HPV) genotypes in the HIV positive population and in invasive cervical cancer (ICC) in Kenya. This may be different from genotypes found in abnormal cytology. Yet, with the advent of preventive HPV vaccines that target HPV 16 and 18, and the nonavalent vaccine targeting 90% of all ICC cases, such HPV genotype distribution data are indispensable for predicting the impact of vaccination and HPV screening on prevention...
2016: PloS One
https://www.readbyqxmd.com/read/27738689/thermal-oxidative-and-ozone-oxidative-stabilization-effect-of-hybridized-functional-graphene-oxide-in-a-silica-filled-solution-styrene-butadiene-elastomer
#12
Juqiao Su, Zhongguo Zhao, Yajiang Huang, Xia Liao, Qi Yang
Hybridization of modified functional graphene oxide (fGO) in silica-filled solution styrene butadiene rubber (SSBR) endows preferable tensile and dynamic properties before and after thermal oxidative aging, and similar mechanical hysteresis performance compared with the composites without fGO. The preventing mechanism of fGO is attributed to its intrinsic peroxy radical scavenging and gas barrier abilities, which significantly reduces the peroxy radical concentration and oxygen permeability of nanocomposites and then prolongs oxidative induction time (OIT), characterized by differential scanning calorimetry (DSC)...
October 14, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27730393/privacy-preserving-and-secure-sharing-of-phr-in-the-cloud
#13
Leyou Zhang, Qing Wu, Yi Mu, Jingxia Zhang
As a new summarized record of an individual's medical data and information, Personal Health Record (PHR) can be accessible online. The owner can control fully his/her PHR files to be shared with different users such as doctors, clinic agents, and friends. However, in an open network environment like in the Cloud, these sensitive privacy information may be gotten by those unauthorized parties and users. In this paper, we consider how to achieve PHR data confidentiality and provide fine-grained access control of PHR files in the public Cloud based on Attribute Based Encryption(ABE)...
December 2016: Journal of Medical Systems
https://www.readbyqxmd.com/read/27696175/m-2-abks-attribute-based-multi-keyword-search-over-encrypted-personal-health-records-in-multi-owner-setting
#14
Yinbin Miao, Jianfeng Ma, Ximeng Liu, Fushan Wei, Zhiquan Liu, Xu An Wang
Online personal health record (PHR) is more inclined to shift data storage and search operations to cloud server so as to enjoy the elastic resources and lessen computational burden in cloud storage. As multiple patients' data is always stored in the cloud server simultaneously, it is a challenge to guarantee the confidentiality of PHR data and allow data users to search encrypted data in an efficient and privacy-preserving way. To this end, we design a secure cryptographic primitive called as attribute-based multi-keyword search over encrypted personal health records in multi-owner setting to support both fine-grained access control and multi-keyword search via Ciphertext-Policy Attribute-Based Encryption...
November 2016: Journal of Medical Systems
https://www.readbyqxmd.com/read/27686702/predicting-intentions-of-nurses-to-adopt-patient-personal-health-records-a-structural-equation-modeling-approach
#15
Min-Huey Chung, Cheng-Hsun Ho, Hsyien-Chia Wen
OBJECTIVE: The American Nurses Association endorsed the use of online patient personal health records (PHRs) and challenged all nurses to obtain the health records of patients. However, few studies have explored the factors associated with the intentions of nurses to use patient PHRs. Our study used an extended technology acceptance model, with the theory of planned behavior and perceived credibility, to explore factors associated with the intentions of nurses to use patient PHRs. METHODS: This cross-sectional quantitative study comprised a sample of 635 nurses who had worked full time for at least 3 months, and they were recruited from three hospitals affiliated with a university in northern Taiwan...
November 2016: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/27683280/the-prognosis-of-women-diagnosed-with-breast-cancer-before-during-and-after-pregnancy-a-meta-analysis
#16
Emily K Hartman, Guy D Eslick
OBJECTIVE: Previous meta-analyses have examined the prognosis of women with pregnancy-associated breast cancer (PABC) as well as pregnancy that follows breast cancer diagnosis. Since then, many additional studies have been performed. We conducted an updated meta-analysis to examine the prognosis for women who become pregnant before, during and after a diagnosis of breast cancer. We also performed analyses on the various subgroups within PABC such as pregnancy and postpartum cases, as well as on time periods postpartum...
November 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27676927/compilio-a-personal-health-record-for-disabled-people
#17
Pascale Roger Dalbert, Marie-Charlotte d'Anjou
Compilio is a free and secure personal health record (PHR). It is an Internet based innovative tool for families and health professionals. Compilio aims to improve the coordination of the care course for people having specific needs related to a handicap or a chronic disease. Compilio is a project of the "Agence régionale de Santé Auvergne-Rhone-Alpes" and the NGO network R4P (Regional Network of Pediatric Re-education and Re-adaptation in Rhône-Alpes), developed with the participation of Civil hospices of Lyon and GCS SISRA...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27668834/the-association-of-graph-literacy-with-use-of-and-skills-using-an-online-personal-health-record-in-outpatient-veterans
#18
Jorge G Ruiz, Allen D Andrade, Christie Hogue, Chandana Karanam, Sisir Akkineni, David Cevallos, Ramanakumar Anam, Joseph Sharit
Personal health records (PHRs) are intended to increase patients' access to and ownership over their health care information for self-management purposes. The purpose of this study was to determine the association of graph literacy with adoption of an online PHR and, among adopters with self-reported skills, the frequency of use and intent to return to use the PHR . We conducted a cross-sectional survey of veterans receiving outpatient care. We measured health literacy, numeracy, graph literacy, and Internet and PHR adoption and use...
2016: Journal of Health Communication
https://www.readbyqxmd.com/read/27601062/high-prevalence-of-human-papillomaviruses-in-ghanaian-pregnant-women
#19
Marco H Schulze, Fabian M Völker, Raimond Lugert, Paul Cooper, Kai Hasenclever, Uwe Groß, Herbert Pfister, Steffi Silling
Data about the prevalence of human papillomaviruses (HPV) in African women with normal and abnormal cervical cytology are still scarce. Current HPV vaccines contain HPV types, which mainly represent the HPV epidemiology of industrial countries. As further developments of HPV vaccines are going on, it is necessary to regard regional differences in HPV type prevalence to ensure optimal protection by the vaccine. Vaginal swabs of Ghanaian pregnant women, routinely collected before delivery to rule out bacterial infections causing early onset sepsis, were screened for 12 high-risk (HR), 13 probably/possibly (pHR), and 18 low-risk (LR) HPV types...
September 6, 2016: Medical Microbiology and Immunology
https://www.readbyqxmd.com/read/27599452/using-tablet-computers-to-increase-patient-engagement-with-electronic-personal-health-records-protocol-for-a-prospective-randomized-interventional-study
#20
S Ryan Greysen, Yimdriuska Magan Mendoza, Jaime Rosenthal, Ronald Jacolbia, Alvin Rajkomar, Herman Lee, Andrew Auerbach
BACKGROUND: Inadequate patient engagement in care is a major barrier to successful transitions from the inpatient setting and can lead to preventable adverse events after discharge, particularly for older adults. While older adults may be less familiar with mobile devices and applications, they may benefit from focused bedside training to engage them in using their Personal Health Record (PHR). Mobile technologies such as tablet computers can be used in the hospital to help bridge this gap in experience by teaching older, hospitalized patients to actively manage their medication list through their PHR during hospitalization and continue to use their PHR for other post-discharge tasks such as scheduling follow-up appointments, viewing test results, and communicating with providers...
September 6, 2016: JMIR Research Protocols
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