keyword
https://read.qxmd.com/read/38506272/benign-prostatic-hyperplasia
#21
JOURNAL ARTICLE
Steven A Kaplan
No abstract text is available yet for this article.
March 20, 2024: Journal of Urology
https://read.qxmd.com/read/38499703/pi-rads-v2-1-evaluation-of-prostate-nodule-in-nodule-variants-clinical-imaging-and-pathological-features
#22
JOURNAL ARTICLE
MingHua Sun, Li Xu, XiaoYan Zhang, LiYu Cao, WenBao Chen, Kai Liu, Hao Wu, DongDong Xie
OBJECTIVES: To analyze the correlation among the imaging features of prostate "nodule in nodule," clinical prostate indices, and pathology results. METHODS: We retrospectively analyzed the prostate images from 47 male patients who underwent MRI scans and pathological biopsy from January 2022 to July 2023. Two radiologists (R1/R2) evaluated the morphology and signal intensity of the "nodule in nodule" in a double-blind manner and calculated the PI-RADS v2.1 score, which was compared with clinical prostate indices and pathological results...
March 18, 2024: Insights Into Imaging
https://read.qxmd.com/read/38490277/moses-tm-technology-versus-non-moses-holmium-laser-enucleation-of-the-prostate-a-randomized-controlled-trial-from-a-high-volume-center
#23
JOURNAL ARTICLE
Zhen Tong, Sherryn Sherryn, Shengqiang Xia, Jie Sun
OBJECTIVES: Benign prostatic hyperplasia (BPH) management has evolved from transurethral resection of the prostate (TURP) to holmium laser enucleation of the prostate (HoLEP). Recent innovation introduces MosesTM technology in holmium lasers, with the Lumenis PulseTM system. METHODS: To compare Moses-augmented HoLEP (MoLEP) to non-Moses HoLEP in terms of enucleation efficiency, hemostasis, and applicability in day surgery settings. A single-blind, prospective, parallel randomized controlled trial was conducted in Shanghai, China, from March to December 2022...
March 13, 2024: Urology
https://read.qxmd.com/read/38488864/exploring-complex-links-inflammatory-rheumatic-diseases-and-men-s-health
#24
REVIEW
Burhan Fatih Kocyigit, Yuliya Fedorchenko, Kassymkhan Sultanbekov, Gulsah Yasa Ozturk, Marlen Yessirkepov
This article examines the complex interactions between inflammatory rheumatic diseases (IRDs) and men's health. It delves into the effects of IRDs on reproductive health, erectile dysfunction, prostate involvement, male osteoporosis, body composition, physical activity, and coping mechanisms. The findings show that the prevalence of sexual dysfunction varies among different diseases, underscoring the necessity for comprehensive counseling. The link between IRDs and prostate health, with a substantial rise in benign prostatic hyperplasia among IRD patients, demonstrates the condition's importance...
March 15, 2024: Rheumatology International
https://read.qxmd.com/read/38485798/nomogram-predicting-the-efficacy-of-transurethral-surgery-in-benign-prostatic-hyperplasia-patients
#25
JOURNAL ARTICLE
Jing Zhou, Zhu-Feng Peng, Lu-Chen Yang, Sheng-Zhuo Liu, Pan Song, Zheng-Huan Liu, Lin-Chun Wang, Jun-Hao Chen, Kai Ma, Yun-Fei Yu, Liang-Ren Liu, Qiang Dong
PURPOSE: This study aimed to develop and validate a nomogram for predicting the efficacy of transurethral surgery in benign prostatic hyperplasia (BPH) patients. METHODS: Patients with BPH who underwent transurethral surgery in the West China Hospital and West China Shang Jin Hospital were enrolled. Patients were retrospectively involved as the training group and were prospectively recruited as the validation group for the nomogram. Logistic regression analysis was utilized to generate nomogram for predicting the efficacy of transurethral surgery...
March 14, 2024: Aging Clinical and Experimental Research
https://read.qxmd.com/read/38484443/sheet-like-interstitial-cells-connect-epithelial-and-smooth-muscle-cells-in-the-mouse-prostate
#26
JOURNAL ARTICLE
Yoshihiro Kawaguchi, Keisuke Ohta, Tasuku Hiroshige, Kei-Ichiro Uemura, Akinobu Togo, Kei-Ichiro Nakamura, Tsukasa Igawa
Epithelial-stromal relationship in the prostate gland is crucial for maintaining homeostasis, including functional differentiation, proliferation, and quiescence. Pathological stromal changes are believed to cause benign prostatic hyperplasia (BPH). The prostate stromal tissue is known to have several subtypes of interstitial cells that connect the epithelium and smooth muscle. However, the characteristics of their morphology and connection patterns are not fully understood. Therefore, we aimed to investigated the three-dimensional morphology and intercellular interactions of interstitial cells in the prostate ventral lobe of mature wild-type mice using immunohistochemistry and focused ion beam-scanning electron microscopy tomography (FIB-SEM tomography)...
March 13, 2024: Acta Histochemica
https://read.qxmd.com/read/38483598/pulse-modulation-in-en-bloc-holep-does-it-really-matter-a-propensity-score-matched-analysis
#27
JOURNAL ARTICLE
Friedrich Otto Hartung, Luisa Egen, Britta Gruene, Maren Juliane Wenk, Karl-Friedrich Kowalewski, Paul Patroi, Marie-Claire Rassweiler-Seyfried, Maurice Stephan Michel, Jonas Herrmann
INTRODUCTION: Holmium laser enucleation of the prostate (HoLEP) is an established option in the surgical treatment of benign prostatic hyperplasia. Pulse modulation, such as MOSES® technology, has recently been introduced and may offer potential advantages in HoLEP. METHODS: Perioperative data from 117 patients who underwent MOSES® laser enucleation of the prostate (MoLEP) were collected. Propensity score matching using prostate volume, age, body mass index (BMI), and anticoagulant intake was performed using a database of 237 patients treated with HoLEP...
March 14, 2024: World Journal of Urology
https://read.qxmd.com/read/38481670/incidental-prostate-cancer-after-holmium-laser-enucleation-of-the-prostate-critical-analysis-of-independent-risk-factors-and-impact-on-surgical-outcomes
#28
JOURNAL ARTICLE
Joao G Porto, Ruben Blachman-Braun, Tarek Ajami, Mohamadhusni Zarli, Ryan Chen, Thiago Furtado, Robert Marcovich, Dipen J Parekh, Hemendra N Shah
OBJECTIVES: The objectives of this study are to evaluate the impact of incidental prostate cancer (iPCa) and its different grade group (GG) on the surgical outcomes of holmium laser enucleation of the prostate (HoLEP) and, furthermore, to assess the independent risk factors associated with the detection of iPCa. PATIENTS OR MATERIALS AND METHODS: A retrospective chart review was conducted at a single institution for HoLEP cases that were performed between 2017 and 2022...
March 2024: BJUI compass
https://read.qxmd.com/read/38481433/the-effects-of-high-fat-diet-on-the-incidence-of-obesity-and-monocyte-chemoattractant-protein-1-levels-on-histological-changes-in-prostate-wistar-rats
#29
JOURNAL ARTICLE
Syarif, Haerani Rasyid, Makbul Aman, Gatot Susilo Lawrence, Agussalim Bukhari, Ilhamjaya Patellongi, Husni Cangara, Muhammad Zulharyahya Dandy Asmara Putra
INTRODUCTION: Benign prostatic hyperplasia (BPH) is a histopathological diagnosis characterized by the increase in stromal cells and epithelial cells of the prostate gland in the transitional zone surrounding the urethra. Obesity is the risk factor of BPH. The most frequent cause of obesity is a high-fat diet (HFD). Obesity and HFD lead to pro-inflammatory conditions. One of the pathomechanisms for the occurrence of BPH is a low-degree inflammatory factor, one of which is the level of monocyte chemoattractant protein-1/MCP-1...
2024: Research and Reports in Urology
https://read.qxmd.com/read/38477358/can-we-predict-and-manage-persistent-storage-and-voiding-luts-following-bladder-outflow-resistance-reduction-surgery-in-men-ici-rs-2023
#30
REVIEW
Tufan Tarcan, Hashim Hashim, Sachin Malde, Sanjay Sinha, Arun Sahai, Omer Acar, Caroline Selai, Enrico Finazzi Agro, Paul Abrams, Alan Wein
AIMS: Lower urinary tract symptoms (LUTS) persist in up to 50% of patients after bladder outflow resistance reduction surgery (BORRS) in men. Our think tank aims to address the predictive factors for persistent LUTS after BORRS and to propose the recommendations for future research to enable improved better patient counseling and selection by more accurate prediction of treatment outcome. METHODS: A think tank of ICI-RS gathered in 2023, Bristol, UK, to discuss the pre and postsurgical clinical and urodynamic evaluation of men undergoing BORRS and whether it is possible to predict which men will have persistent LUTS after BORRS...
March 13, 2024: Neurourology and Urodynamics
https://read.qxmd.com/read/38476919/secondary-bladder-stone-caused-by-delayed-penetration-of-the-bladder-by-a-pubic-fracture-a-case-report-and-literature-review
#31
Xinghao Wang, Xiao Guo, Zhiling Tang, Xiangjun Ying, Chenye Tang, Ruilin Shen
Pelvic fractures sometimes lead to injuries of the urinary bladder, which commonly present as gross hematuria, dysuria and lower abdominal pain. As a type of urinary stone, bladder stones are usually secondary to lower urinary tract obstruction, such as benign prostatic hyperplasia, urethral stricture, and neurogenic bladder. The present case report examines an unusual case of a delayed pubic fracture penetrating the bladder, which caused a secondary bladder stone. A 53-year-old man was first hospitalized at The Second Hospital of Jiaxing (Jiaxing, China) in January 2020 because of trauma-induced bleeding in the scalp and abdominal pain...
April 2024: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/38474555/chickpea-sprouts-as-a-potential-dietary-support-in-different-prostate-disorders-a-preliminary-in-vitro-study
#32
JOURNAL ARTICLE
Agnieszka Galanty, Ewelina Prochownik, Marta Grudzińska, Paweł Paśko
BACKGROUND: Prostate cancer (PC) and benign prostatic hyperplasia (BPH) are common health problems in the aging male population. Due to the unexplored and unconfirmed impact of food containing isoflavones, like sprouts, on the development of the management of BPH and prostate cancer, we decided to extend the knowledge in this area. RESULTS: We have demonstrated for the first time that chickpea sprouts may play an important role in the chemoprevention of prostate disorders...
February 28, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38473877/integrative-metabolomic-analysis-of-serum-and-selected-serum-exosomal-microrna-in-metastatic-castration-resistant-prostate-cancer
#33
JOURNAL ARTICLE
Daniel Evin, Andrea Evinová, Eva Baranovičová, Miroslava Šarlinová, Jana Jurečeková, Peter Kaplán, Hubert Poláček, Erika Halašová, Róbert Dušenka, Lukáš Briš, Martina Knoško Brožová, Monika Kmeťová Sivoňová
Metastatic castration-resistant prostate cancer (mCRPC) remains a lethal disease due to the absence of effective therapies. A more comprehensive understanding of molecular events, encompassing the dysregulation of microRNAs (miRs) and metabolic reprogramming, holds the potential to unveil precise mechanisms underlying mCRPC. This study aims to assess the expression of selected serum exosomal miRs (miR-15a, miR-16, miR-19a-3p, miR-21, and miR-141a-3p) alongside serum metabolomic profiling and their correlation in patients with mCRPC and benign prostate hyperplasia (BPH)...
February 23, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38470547/evaluation-of-current-surgical-bph-interventions-for-young-and-elderly-men
#34
REVIEW
Timothy W Brandt, Jacqueline M Luizzi, Ronald J Caras
PURPOSE OF REVIEW: Benign prostatic hyperplasia affects the quality of life of a significant number of men, especially as they age. There are continuous innovations in the surgical management of benign prostatic hyperplasia, but many of these innovations are studied in the core population of men 50-70 years of age. This review focuses on the outliers of men aged 18-50 and 70 and older. RECENT FINDINGS: Older populations have more comorbidities, higher rates of antithrombotic medications, and advanced symptoms...
March 12, 2024: Current Urology Reports
https://read.qxmd.com/read/38468109/micro-nanofluidic-device-for-tamsulosin-therapeutic-drug-monitoring-in-patients-with-benign-prostatic-hyperplasia-at-point-of-care
#35
JOURNAL ARTICLE
Zaidon T Al-Aqbi, Hassan T Abdulsahib, Faris A J Al-Doghachi
Discovering the balance between toxicity and efficacy for many drugs requires therapeutic drug monitoring (TDM) of their concentrations in the blood. Here, a hot-embossed microfluidic device with a new design integrated to a nanofracture is presented for purification of blood samples from numerous proteins and cells, allowing to the separation of small molecules from blood matrix. The device was used to separate and quantitatively detect tamsulosin drug after derivatization with fluorescamine reagent, allowing converting it from a neutral molecule into a charged fluorescent complex under the experimental conditions, and thus its separation by electrophoresis...
March 11, 2024: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://read.qxmd.com/read/38467289/influence-of-early-apical-release-on-outcomes-in-endoscopic-enucleation-of-the-prostate-results-from-a-multicenter-series-of-4392-patients
#36
JOURNAL ARTICLE
Vineet Gauhar, Ee Jean Lim, Khi Yung Fong, Fernando Gómez Sancha, Moisés Rodríguez Socarrás, Dmitry Enikeev, Mario Sofer, Azimdjon N Tursunkulov, Dean Elterman, Mohammed Taif Bendigeri, Jeremy Yuen-Chun Teoh, Abhay Mahajan, Tanuj Pal Bhatia, Sorokin Nikolai Ivanovich, Nariman Gadzhiev, Lie Kwok Ying, Biligere Sarvajit, Bhaskar Kumar Somani, Thomas R W Herrmann, Daniele Castellani
OBJECTIVE: To evaluate outcomes after laser Endoscopic enucleation of the prostate (EEP) stratified by whether early apical release (EAR) was performed or not. METHODS: We retrospectively reviewed patients with clinical benign prostatic hyperplasia who underwent EEP with holmium or thulium fiber laser in 8 centers (January 2020-January 2022). EXCLUSION CRITERIA: previous prostate/urethral surgery, prostate cancer, pelvic radiotherapy, concomitant lower urinary tract surgery...
March 9, 2024: Urology
https://read.qxmd.com/read/38466193/cost-effectiveness-analysis-of-minimally-invasive-surgical-treatments-for-benign-prostatic-hyperplasia-implications-for-japan-s-public-healthcare-system
#37
JOURNAL ARTICLE
Hisataka Anezaki, Fumiyasu Endo, Georgia Swan, Kenta Takashima, Sirikan Rojanasarot
AIMS: Benign prostatic hyperplasia (BPH) represents a significant public health issue in Japan. This study evaluated the lifetime cost-effectiveness of water vapor energy therapy (WAVE) versus prostatic urethral lift (PUL) for men with moderate-to-severe BPH from a public healthcare payer's perspective in Japan. MATERIALS AND METHODS: A decision analytic model compared WAVE to PUL among males in Japan. Clinical effectiveness and adverse event (AE) inputs were obtained from a systematic literature review...
March 11, 2024: Journal of Medical Economics
https://read.qxmd.com/read/38462732/intrinsic-and-extrinsic-factors-causing-hyperplasia-of-the-prostate
#38
REVIEW
Yuki Kyoda, Kosuke Shibamori, Tetsuya Shindo, Takeshi Maehana, Kohei Hashimoto, Ko Kobayashi, Toshiaki Tanaka, Fumimasa Fukuta, Naoya Masumori
Prostatic hyperplasia is very common in elderly men and is a typical disease that reduces quality of life. Histologically, hyperplasia of the prostate gland causes obstruction at the bladder outlet, resulting in symptoms such as a weak urine stream. Various factors have been considered to cause histological enlargement of the prostate, but the underlying cause is still unknown. The factors that cause prostate hyperplasia can be broadly classified into intrinsic and extrinsic ones. Extrinsic factors include things that we directly come into contact with such as bacteria and food...
March 10, 2024: International Journal of Urology: Official Journal of the Japanese Urological Association
https://read.qxmd.com/read/38461856/adreno-muscarinic-synergy-of-contractile-responses-from-human-hyperplastic-prostate
#39
JOURNAL ARTICLE
Ben T Blake-James, Basu Chakrabarty, Christopher H Fry
PURPOSE: Adreno-muscarinic synergy, a supra-additional contractile response to simultaneous application of α-adrenoreceptor and muscarinic receptor agonists, is a feature of several lower urinary tract regions that have dual sympathetic and parasympathetic innervation. We tested the hypothesis that synergy is also a feature of prostate tissue obtained from men with benign prostatic enlargement. METHODS: Isolated tissue strips were dissected from prostate 'chips', collected after transurethral prostate resection procedures for in vitro experiments, to measure isometric tension at 36°C...
February 2024: International Neurourology Journal
https://read.qxmd.com/read/38460003/association-between-chronic-prostatitis-and-the-subsequent-benign-prostatic-hyperplasia-a-population-based-national-cohort-study
#40
JOURNAL ARTICLE
Tsung-Yen Lin, I-Hung Chen, Han-Yu Weng, Yu-Chiao Lin, Chien-Hui Ou, Chung-Yi Li, Yu-Sheng Cheng
PURPOSE: To explore the association between chronic prostatitis (CP) and the subsequent development of benign prostatic hyperplasia (BPH). METHODS: Data analyzed were medical claims of Taiwan's National Health Insurance program. From 2010 to 2017, 3571 patients ≧20 years with CP diagnosed by certified urologists were enrolled. Patients with past BPH diagnosis and diagnosis of prostate cancer, inguinal hernia, interstitial cystitis, and urethritis in the past and within one year after the first CP diagnosis were excluded...
March 9, 2024: World Journal of Urology
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