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Achilles tendinopathy

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https://www.readbyqxmd.com/read/28301205/intratendon-delivery-of-leukocyte-poor-platelet-rich-plasma-improves-healing-compared-with-leukocyte-rich-platelet-rich-plasma-in-a-rabbit-achilles-tendinopathy-model
#1
Ruijian Yan, Yanjia Gu, Jisheng Ran, Yejun Hu, Zefeng Zheng, Mengfeng Zeng, Boonchin Heng, Xiao Chen, Zi Yin, Weishan Chen, Weiliang Shen, Hongwei Ouyang
BACKGROUND: Chronic tendinopathy is a commonly occurring clinical problem that affects both athletes and inactive middle-aged patients. Although some studies have shown that different platelet-rich plasma (PRP) preparations could exert various therapeutic effects in vitro, the role of leukocytes in PRP has not yet been defined under tendinopathy conditions in vivo. PURPOSE: This study compared the effects of the intratendon delivery of leukocyte-poor PRP (Lp-PRP) versus leukocyte-rich PRP (Lr-PRP) in a rabbit chronic tendinopathy model in vivo...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28294413/acute-effect-of-running-exercise-on-physiological-achilles-tendon-blood-flow
#2
Lucie Risch, Michael Cassel, Frank Mayer
Sonographically detectable intratendinous blood flow (IBF) is found in 50-88% of Achilles tendinopathy patients as well as in up to 35% of asymptomatic Achilles tendons (AT). Although IBF is frequently associated with tendon pathology, it may also represent a physiological regulation e.g. due to increased blood flow in response to exercise. Therefore, this study aimed to investigate the acute effects of a standardized running exercise protocol on IBF assessed with Doppler ultrasound (DU) "Advanced dynamic flow" in healthy ATs...
March 13, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28291954/therapeutic-mechanisms-of-human-adipose-derived-mesenchymal-stem-cells-in-a-rat-tendon-injury-model
#3
Sang Yoon Lee, Bomi Kwon, Kyoungbun Lee, Young Hoon Son, Sun G Chung
BACKGROUND: Although survival of transplanted stem cells in vivo and differentiation of stem cells into tenocytes in vitro have been reported, there have been no in vivo studies demonstrating that mesenchymal stem cells (MSCs) could secrete their own proteins as differentiated tenogenic cells. Purpose/Hypothesis: Using a xenogeneic MSC transplantation model, we aimed to investigate whether MSCs could differentiate into the tenogenic lineage and secrete their own proteins. The hypothesis was that human MSCs would differentiate into the human tenogenic lineage and the cells would be able to secrete human-specific proteins in a rat tendon injury model...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28289916/predicting-tenocyte-expression-profiles-and-average-molecular-concentrations-in-achilles-tendon-ecm-from-tissue-strain-and-fiber-damage
#4
Arash Mehdizadeh, Bruce S Gardiner, Michael Lavagnino, David W Smith
In this study, we propose a method for quantitative prediction of changes in concentrations of a number of key signaling, structural and effector molecules within the extracellular matrix of tendon. To achieve this, we introduce the notion of elementary cell responses (ECRs). An ECR defines a normal reference secretion profile of a molecule by a tenocyte in response to the tenocyte's local strain. ECRs are then coupled with a model for mechanical damage of tendon collagen fibers at different straining conditions of tendon and then scaled up to the tendon tissue level for comparison with experimental observations...
March 13, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28289634/long-term-outcome-and-factors-affecting-prognosis-of-extracorporeal-shockwave-therapy-for-chronic-refractory-achilles-tendinopathy
#5
Joon-Youn Lee, Kyungjae Yoon, Youbin Yi, Chul-Hyun Park, Jung-Sang Lee, Kyoung-Ho Seo, Young Sook Park, Yong-Taek Lee
OBJECTIVE: To investigate the factors affecting prognosis of extracorporeal shockwave therapy (ESWT) for chronic refractory Achilles tendinopathy (AT). METHODS: Thirty-six patients (48 consecutive feet) with chronic AT (>6 months) and who underwent ESWT for 'poor' or 'fair' grade in Roles-Maudsley Score (RMS) after unsuccessful conservative treatment were included in the present study. A maximum of 12 sessions of ESWT were conducted until treatment success: RMS reached 'good' or 'excellent'...
February 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28258946/achilles-impingement-tendinopathy-on-magnetic-resonance-imaging
#6
Mark J Bullock, Jan Mourelatos, Alice Mar
Haglund's syndrome is impingement of the retrocalcaneal bursa and Achilles tendon caused by a prominence of the posterosuperior calcaneus. Radiographic measurements are not sensitive or specific for diagnosing Haglund's deformity. Localization of a bone deformity and tendinopathy in the same sagittal section of a magnetic resonance imaging scan can assist with the diagnosis in equivocal cases. The aim of the present cross-sectional study was to determine the prevalence of Haglund's syndrome in patients presenting with Achilles tendinopathy and note any associated findings to determine the criteria for a diagnosis of Haglund's syndrome...
February 28, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28257674/insertional-achilles-tendinopathy
#7
REVIEW
Gage M Caudell
Posterior heel pain is a common condition of the foot and ankle and is seen in a variety of foot types. Nonoperative treatment methods consisting of shoes inserts, heel lifts, stretching, physical therapy, nonsteroidal antiinflammatory drugs, eccentric strength training, and other modalities have been shown to have mixed results. When indicated, surgical repair can produce good long-term results. Complications, although uncommon, most commonly result from wound healing complications.
April 2017: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/28257673/midsubstance-tendinopathy-surgical-management
#8
REVIEW
William T DeCarbo, Mark J Bullock
Noninsertional Achilles tendinopathy often responds to nonoperative treatment. When nonoperative treatment fails, the clinician must distinguish between paratendinopathy and noninsertional tendinopathy. In paratendinopathy, myofibroblasts synthesize collagen, causing adhesions, and the paratenon may be released or excised. If a core area of tendinopathy is identified on MRI, the area is excised longitudinally and repaired with a side-to-side suture. If greater than 50% of the tendon diameter is excised, the authors recommend a short flexor hallucis longus tendon transfer with an interference screw...
April 2017: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/28257672/midsubstance-tendinopathy-percutaneous-techniques-platelet-rich-plasma-extracorporeal-shock-wave-therapy-prolotherapy-radiofrequency-ablation
#9
REVIEW
William Bret Smith, Will Melton, James Davies
The focus of this article is to present the current options available for noninvasive and percutaneous treatment options for noninsertional Achilles tendinopathy. An attempt is made to offer recommendations for both the treatment techniques as well as postprocedure protocols to be considered. Additionally, because there are numerous treatment options in this category, the different techniques are summarized in a chart format with a short list of pros and cons as well as the levels of evidence in the literature to support the different modalities...
April 2017: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/28257671/nonsurgical-management-of-midsubstance-achilles-tendinopathy
#10
REVIEW
Shane McClinton, Lace Luedke, Derek Clewley
Midsubstance Achilles tendinopathy is one of the most common lower leg conditions. Most patients can recover with nonsurgical treatment that focuses on tendon loading exercises and, when necessary, symptom modulating treatments such as topical, oral, or injected medication, ice, shoe inserts, manual therapy, stretching, taping, or low-level laser. If unresponsive to initial management, a small percentage of patients may consider shockwave or sclerosing treatment and possibly surgery.
April 2017: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/28257670/noninsertional-achilles-tendinopathy-pathologic-background-and-clinical-examination
#11
REVIEW
Mindi Feilmeier
The term tendinopathy includes a series of pathologies, all of which have a combination of pain, swelling, and impaired performance. The terms tendinosis, tendinitis and peritendinitis are all within the main heading of tendinopathy; this terminology provides a more accurate understanding of the condition and highlights the uniformity of clinical findings while distinguishing the individual histopathological findings of each condition. Understanding the clinical features and the underlying histopathology leads to a more accurate clinical diagnosis and subsequent treatment selection...
April 2017: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/28251260/intratendinous-adipose-derived-stromal-vascular-fraction-svf-injection-provides-a-safe-efficacious-treatment-for-achilles-tendinopathy-results-of-a-randomized-controlled-clinical-trial-at-a-6-month-follow-up
#12
Federico Giuseppe Usuelli, Miriam Grassi, Camilla Maccario, Marco Vigano', Luciano Lanfranchi, Umberto Alfieri Montrasio, Laura de Girolamo
PURPOSE: Although platelet-rich plasma (PRP) injection has shown controversial results for the treatment of Achilles tendinopathy, it remains the most used biological treatment. Recent findings seem to demonstrate that the stromal vascular fraction (SVF) within adipose tissue may counteract the impaired tendon homeostasis. The aim of this study was to prospectively compare the efficacy of PRP and SVF injection for the treatment of non-insertional Achilles tendinopathy. METHODS: Fourty-four patients were recruited in the study; 23 of them were assigned to the PRP group whereas 21 to the SVF group, treated unilaterally or bilaterally for a total of 28 tendons per group...
March 1, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28236094/-diseases-and-overuse-injuries-of-the-lower-extremities-in-long-distance-runners
#13
REVIEW
M Tschopp, F Brunner
Running is one of the most popular sports worldwide, with running events attracting hundreds of thousands of runners of all age groups. Running is an effective way to improve health but is also associated with a high risk of injuries. Up to 50% of regular runners report having more than one injury each year. Some injuries are caused by an accident but most are caused by overuse. The most frequent diagnoses are patellofemoral pain syndrome, tibial stress syndrome (shin splint), Achilles tendinopathy, iliotibial band friction syndrome (runner's knee), plantar fasciitis and stress fractures of the metatarsals and tibia...
February 24, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28229814/could-leptin-deficient-mice-be-good-novel-models-for-diabetic-achilles-tendinopathy
#14
Min-Jun Huang, Can-Jun Zeng, Liang Wang
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February 10, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28229813/reply-to-could-leptin-deficient-mice-be-good-novel-models-for-diabetic-achilles-tendinopathy-by-m-j-huang-et-al
#15
Jinfei Ji, Qing Jiang
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February 10, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28222571/the-edurep-approach-plus-manual-therapy-for-the-management-of-insertional-achilles-tendinopathy-a-case-report
#16
Francesco Sartorio, Anna Zanetta, Giorgio Ferriero, Elisabetta Bravini, Stefano Vercelli
BACKGROUND: Insertional Achilles tendinopathy (IAT) is a challenging overuse disorder. The aim of this case report was to study the feasibility of a comprehensive rehabilitative approach according to the Education, Unloading, Reloading, and Prevention (EdUReP) framework combined with Instrument-Augmented Soft Tissue Mobilization (I-ASTM). METHODS: An active 51-year-old man patient with chronic IAT was studied. Clinical assessment battery was composed by visual analogue scale for pain during the Achilles tendon palpation test, passive straight leg raise test, single leg hop test, Patient-Specific Functional Scale, and Foot and Ankle Ability Measure...
February 21, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28217424/joint-mobilization-in-the-management-of-persistent-insertional-achilles-tendinopathy-a-case-report
#17
Dhinu J Jayaseelan, Andrew A Post, John J Mischke, Josiah D Sault
BACKGROUND & PURPOSE: Insertional Achilles tendinopathy (IAT) can be a challenging condition to manage conservatively. Eccentric exercise is commonly used in the management of chronic tendinopathy; however, it may not be as helpful for insertional tendon problems as compared to mid-portion dysfunction. While current evidence describing the physical therapy management of IAT is developing, gaps still exist in descriptions of best practice. The purpose of this case report is to describe the management of a patient with persistent IAT utilizing impairment-based joint mobilization, self-mobilization, and exercise...
February 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28203584/plantaris-excision-reduces-pain-in-midportion-achilles-tendinopathy-even-in-the-absence-of-plantaris-tendinosis
#18
James D F Calder, Joanna M Stephen, C Niek van Dijk
BACKGROUND: It is becoming increasingly apparent that the plantaris can contribute to symptoms in at least a subset of patients with midportion Achilles tendinopathy. However, the nature of its involvement remains unclear. PURPOSE: To determine whether excised plantaris tendons from patients with midportion Achilles tendinopathy display tendinopathic changes and whether the presence of such changes affect clinical outcomes. STUDY DESIGN: Case series; Level of evidence, 4...
December 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28194638/achilles-tendon-injuries
#19
REVIEW
Anthony C Egger, Mark J Berkowitz
PURPOSE OF REVIEW: The purpose of this study is to review the current literature of Achilles tendon injuries, specifically chronic tendinopathy and acute ruptures in regard to etiology, diagnosis, treatment options, and outcomes. RECENT FINDINGS: The incidence of Achilles tendon injuries is increasing, but the necessity for surgical intervention is decreasing due to improved conservative therapies, which may provide comparable outcomes without the implied surgical risk...
March 2017: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/28169151/value-of-quantitative-mri-parameters-in-predicting-and-evaluating-clinical-outcome-in-conservatively-treated-patients-with-chronic-midportion-achilles-tendinopathy-a-prospective-study
#20
J Tsehaie, D H J Poot, E H G Oei, J A N Verhaar, R J de Vos
OBJECTIVES: To evaluate whether baseline MRI parameters provide prognostic value for clinical outcome, and to study correlation between MRI parameters and clinical outcome. DESIGN: Observational prospective cohort study. METHODS: Patients with chronic midportion Achilles tendinopathy were included and performed a 16-week eccentric calf-muscle exercise program. Outcome measurements were the validated Victorian Institute of Sports Assessment-Achilles (VISA-A) questionnaire and MRI parameters at baseline and after 24 weeks...
January 24, 2017: Journal of Science and Medicine in Sport
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