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Otitis media with effusion

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https://www.readbyqxmd.com/read/29775023/-the-role-of-th1-th2-cells-imbalance-in-the-pathogenesis-of-secretory-otitis-media
#1
Z H Li, Q Y Fu, Z Y Li, K X Wang, Y C Xu, J P Xue
Objective: The aim of this study is to explore the role of Th1/Th2 cells imbalance in the pathogenesis of secretory otitis media. Method: Ninety secretory otitis media patients were enrolled in observation group. According to medical history, they were divided into acute and chronic group. In addition, 90 healthy volunteers during the same period were selected as the control group. The levels of Th1-type cytokines IFN-γ, Th2-type cytokines interleukin-4 (IL-4) and IFN-γ/IL-4 in peripheral blood were compared between observation group and control group...
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29764792/otitis-media-with-effusion-revealing-underlying-meningioma
#2
Diane Evrard, Mary Daval, Denis Ayache
Otitis media with effusion (OME) is a very common condition in the current clinical practice. Usually idiopathic, it may sometimes be the consequence of primary diseases. Extracranial meningioma is rare, and even more when involving the ear and temporal bone. We report a case of temporal meningioma spreading to the middle ear and mastoid presenting as an OME. The diagnosis relies on a thorough imaging evaluation with computed tomography and magnetic resonance imaging. This short report aims to warn the otolaryngologist of this rare situation to prevent any delay in diagnosing and managing such a condition...
April 2018: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29764778/lower-beclin-1-mrna-levels-in-pediatric-compared-with-adult-patients-with-otitis-media-with-effusion
#3
Kim Sang Hoon, Kim Myung Gu, Shim Haeng Seon, Kim Sung Su, Kim Young Il, Yeo Seung Geun
OBJECTIVES: The role of autophagy in the pathophysiology of otitis media with effusion (OME) remains unclear, particularly regarding the difference between pediatric and adult patients. The present study analyzed the expression levels of autophagy-associated mRNAs in effusion fluids obtained from pediatric and adult patients with OME. MATERIALS AND METHODS: Middle ear fluid samples were collected from 76 pediatric patients and 41 adult patients with OME, and the levels of mRNAs encoding autophagy-related genes were measured using real-time reverse transcription-polymerase chain reaction...
April 2018: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29759911/management-of-otitis-media-with-effusion-in-children-soci%C3%A3-t%C3%A3-fran%C3%A3-aise-d-orl-et-de-chirurgie-cervico-faciale-clinical-practice-guidelines
#4
F Blanc, D Ayache, M N Calmels, O Deguine, M François, N Leboulanger, E Lescanne, R Marianowski, J Nevoux, R Nicollas, S Tringali, N Tessier, V Franco-Vidal, P Bordure, M Mondain
The Société française d'ORL et de chirurgie cervico-faciale clinical practice guidelines concern the management of otitis media with effusion (OME) in children under the age of 12 years. They are based on extensive review of MEDLINE and Cochrane Library publications in English or French from 1996 to 2016 concerning the methods of diagnosis and assessment of otitis media with effusion, as well as the efficacy of tympanostomy tubes and medical and surgical treatments of OME.
May 11, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29753496/an-evidence-based-protocol-for-managing-neonatal-middle-ear-effusions-in-babies-who-fail-newborn-hearing-screening
#5
Brittany C Weber, Scott M Whitlock, Kaidi He, Blake S Kimbrell, Craig S Derkay
OBJECTIVES: To evaluate the prevalence of middle ear disease in infants referred for failed newborn hearing screening (NBHS) and to review patient outcomes after intervention in order to propose an evidence-based protocol for management of newborns with otitis media with effusion (OME) who fail NBHS. METHODS: 85 infants with suspected middle ear pathology were retrospectively reviewed after referral for failed NBHS. All subjects underwent a diagnostic microscopic exam with myringotomy with or without placement of a ventilation tube in the presence of a middle ear effusion and had intra-operative auditory brainstem response (ABR) testing or testing at a later date...
April 12, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29741289/grommets-ventilation-tubes-for-recurrent-acute-otitis-media-in-children
#6
REVIEW
Roderick P Venekamp, Paul Mick, Anne Gm Schilder, Desmond A Nunez
BACKGROUND: Acute otitis media (AOM) is one of the most common childhood illnesses. While many children experience sporadic AOM episodes, an important group suffer from recurrent AOM (rAOM), defined as three or more episodes in six months, or four or more in one year. In this subset of children AOM poses a true burden through frequent episodes of ear pain, general illness, sleepless nights and time lost from nursery or school. Grommets, also called ventilation or tympanostomy tubes, can be offered for rAOM...
May 9, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29728166/long-term-evaluation-of-the-effect-of-middle-ear-effusion-on-the-vestibular-system-in-children
#7
Katarzyna Pazdro-Zastawny, Lucyna Pośpiech, Tomasz Zatoński
BACKGROUND: Otitis media with effusion (OME) is one of the most common clinical conditions in childhood. Fluid accumulation in the middle ear may impact inner ear. OBJECTIVES: The purpose of this random sample cohort study was to investigate whether the past history of middle ear effusion has a long-term negative impact on the vestibular system in children. MATERIAL AND METHODS: The study was carried out on 22 children aged 7-15 years who had undergone drainage of the middle ear 5 years before evaluation...
June 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29699430/current-evidence-of-peripheral-vestibular-symptoms-secondary-to-otitis-media
#8
Rafael Costa Monsanto, Ana Luiza Papi Kasemodel, Andreza Tomaz, Michael M Paparella, Norma O Penido
BACKGROUND: The association between otitis media and vestibular symptoms has been hypothesized in the past. Thus, in this study, we aimed to critically analyze (based in a systematic review of the literature) whether patients who have otitis media are at greater risk of developing vestibular impairment or not. METHODS: We performed a systematic review of the literature, and identified potentially relevant articles reporting vestibular symptoms and results of vestibular function tests in patients with otitis media through searches of the PubMED, Web of Science, Scopus, and Google Scholar databases...
April 26, 2018: Annals of Medicine
https://www.readbyqxmd.com/read/29698103/otitis-media-with-effusion-after-radiotherapy-of-the-head-and-neck-a-systematic-review
#9
J G Christensen, I Wessel, A B Gothelf, P Homøe
BACKGROUND: Otitis media (OM) and associated hearing problems may be side effects to radiotherapy of the head and neck region and affect patient quality of life. The condition is associated with the tumor location. OBJECTIVE: To perform a systematic review concerning the present knowledge of the risk of OM after radiotherapy of the head and neck. METHODS: A comprehensive search of PubMed and Embase was carried out between 1 October 2015 and 6 February 2017...
April 26, 2018: Acta Oncologica
https://www.readbyqxmd.com/read/29644162/clinical-study-on-middle-ear-diseases-in-children-with-orofacial-clefts
#10
Raja Kalaiarasi, Kamran A Syed, Chellappa Vijayakumar, Ajoy M Varghese, Mary John
Introduction Orofacial clefts are associated with middle ear diseases, but the magnitude of this problem is not generally well appreciated. The aim of this study was to describe the middle ear findings and audiological profile in children with orofacial clefts. Materials and methods Children with orofacial clefts attending plastic surgery and otorhinolaryngology departments of a tertiary hospital over one-year duration were included in this study. Ninety-six children with orofacial clefts were identified. They were categorized age-wise as zero to five years, more than five years to 10 years, and more than 10 years to 15 years...
February 8, 2018: Curēus
https://www.readbyqxmd.com/read/29609841/the-safety-and-risk-factors-of-revision-adenoidectomy-in-children-and-adolescents-a-nationwide-retrospective-population-based-cohort-study
#11
Dai-Lou Lin, Chuan-Song Wu, Chao-Hsiun Tang, Ting-Yu Kuo, Tzong-Yang Tu
OBJECTIVE: To investigate the safety of adenoidectomy and risk factors of re-adenoidectomy, and intend to provide evidence-based information to clinicians for further consideration. METHODS AND MATERIALS: This study was based on data obtained from Taiwan's National Health Insurance Research Database from the period 2002-2011. We utilized that data from the hospitalization group and collected information regarding those individuals who accepted adenoidectomy with or without tonsillectomy and post-adenoidectomy bleeding...
March 30, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29607712/expression-of-aquaporins-mrnas-in-patients-with-otitis-media
#12
Su Young Jung, Sung Su Kim, Young Il Kim, Hyung-Sik Kim, Sang Hoon Kim, Seung Geun Yeo
OBJECTIVE: This study analyzed the associations between measured levels of aquaporin (AQP) mRNAs and clinical manifestations in patients with various types of otitis media (OM). METHODS: AQP1, 2, 3, 4, 5, 6, 8, and 10 mRNA levels were assayed by real-time PCR from 57 patients with chronic otitis media (COM), 24 patients with cholesteatomatous otitis media (choleOM), and 82 patients with otitis media with effusion (OME). The relationships of these mRNA levels with the presence of bacteria, the type of hearing loss, and clinical manifestations of OM types were evaluated...
April 1, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29603354/combined-multichannel-intraluminal-impedance-ph-monitoring-should-be-used-to-diagnose-reflux-related-otitis-media-with-effusion-in-children
#13
Ivan Pavić, Irena Babić, Nuša Matijašić, Iva Hojsak
AIMS: This study investigated the diagnostic usefulness of combined multichannel intraluminal impedance-pH monitoring (MII-pH) in children with suspected reflux-related otitis media with effusion (OME) as existing data were scarce. METHODS: This was a prospective study that included children up to seven years of age who underwent MII-pH due to OME lasting more than three months. The study was conducted in the Children's Hospital Zagreb, Croatia, from January 2014 to August 2016...
March 30, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29600829/our-experience-of-the-necessity-of-adenoidectomy-or-adenotonsillectomy-at-the-time-of-ventilation-tube-insertion-in-11-941-children-with-middle-ear-effusion
#14
James Johnston, Gabrielle Kinzett-Carran, Murali Mahadevan, Richard G Douglas
Adenoidectomy and tonsillectomy are commonly performed at the time of myringotomy plus ventilation tube insertion (MVTI) in children with otitis media with effusion (OME). However, the evidence supporting this practice is not conclusive. This is because uncertainty remains regarding the pathogenic role of the adenoids in OME. It is unclear if mechanical obstruction is a more or less important factor than the adenoids' role as a bacterial reservoir. Some studies show that children who have large adenoids removed have higher rates of effusion resolution compared to those children with small adenoids...
March 30, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29593875/long-term-low-dose-of-clarithromycin-as-a-cause-of-community-acquired-clostridium-difficile-infection-in-a-5-year-old-boy
#15
Hirofumi Namiki, Tadashi Kobayashi
Clostridium difficile is one of the most common causes of antibiotic-associated diarrhoea. Despite C. difficile infection (CDI) has increased in all ages worldwide, episodes of CDI are often misdiagnosed due to the lack of clinical suspicion. Macrolides are also associated with CDI. Additionally, exposure to macrolides in the 12 weeks preceding infection is reported to be a significant risk factor of CDI in a child. We report here a 5-year-old Japanese boy who presented with acute onset of watery diarrhoea...
March 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29587475/microbiological-results-from-middle-ear-effusion-in-pediatric-patients-receiving-ventilation-tube-insertion-multicenter-registry-study-on-the-effectiveness-of-ventilation-tube-insertion-in-pediatric-patients-with-chronic-otitis-media-with-effusion-part-i
#16
Myung Hoon Yoo, Yang-Sun Cho, June Choi, Yun Hoon Choung, Jae-Ho Chung, Jong Woo Chung, Gyu Cheol Han, Eun-Ju Jeon, Beom Cho Jun, Dong-Kee Kim, Kyu Sung Kim, Jun Ho Lee, Kyu-Yup Lee, Seung Hwan Lee, In Seok Moon, Hong Ju Park, Shi Nae Park, Jihye Rhee, Jae Hyun Seo, Seung Geun Yeo
Objectives: The aim of this multicenter registry study was to investigate the effectiveness of ventilation tube insertion and the microbiology of otitis media with effusion (OME) in children. This part I study was conducted to evaluate the microbiological profile of children with OME who needed ventilation tube insertion. Methods: Patients <15 years old who were diagnosed as having OME and received ventilation tube insertion were prospectively enrolled in 16 tertiary hospitals from June 2014 to December 2016...
March 28, 2018: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/29573766/-quality-of-life-of-children-with-otitis-media-and-impact-of-insertion-of-transtympanic-ventilation-tubes-in-a-portuguese-population
#17
Ana Rita Lameiras, Deodato Silva, Assunção O Neill, Pedro Escada
INTRODUCTION: Quality of life is an important measure for health-outcome evaluation. Although otitis media is one of the most common childhood diseases, its impact on Portuguese children's quality of life is unknown. The aim of this study is to determine the quality of life of Portuguese children with chronic otitis media with effusion and/or recurrent acute otitis media and the short-term impact of transtympanic ventilation tubes, using the Portuguese version of the OM-6 questionnaire, a valid, reliable and sensitive instrument to evaluate the health-related quality of life in children with otitis media...
January 31, 2018: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/29554447/surveillance-of-otitis-media-with-effusion-in-thai-children-with-cleft-palate-cumulative-incidence-and-outcome-of-the-management
#18
Kitirat Ungkanont, Panrasee Boonyabut, Chulaluk Komoltri, Archwin Tanphaichitr, Vannipa Vathanophas
OBJECTIVE: To study the incidence and outcome of management of otitis media with effusion in Thai children with cleft palate. DESIGN: Retrospective cohort study in the tertiary care center. PATIENTS: Ninety-five children with cleft palate were referred for ear evaluation, from June 1997 to January 2015. Fifteen children (15.8%) had associated craniofacial syndromic anomalies. MAIN OUTCOME MEASURES: Cumulative incidence of otitis media with effusion, rate of ventilation tube insertion, duration of indwelling tubes, hearing outcome, and complications of ventilation tubes...
April 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29552381/pneumatic-low-coherence-interferometry-otoscope-to-quantify-tympanic-membrane-mobility-and-middle-ear-pressure
#19
Jungeun Won, Guillermo L Monroy, Pin-Chieh Huang, Roshan Dsouza, Malcolm C Hill, Michael A Novak, Ryan G Porter, Eric Chaney, Ronit Barkalifa, Stephen A Boppart
Pneumatic otoscopy to assess the mobility of the tympanic membrane (TM) is a highly recommended diagnostic method of otitis media (OM), a widespread middle ear infection characterized by the fluid accumulation in the middle ear. Nonetheless, limited depth perception and subjective interpretation of small TM displacements have challenged the appropriate and efficient examination of TM dynamics experienced during OM. In this paper, a pneumatic otoscope integrated with low coherence interferometry (LCI) was adapted with a controlled pressure-generating system to record the pneumatic response of the TM and to estimate middle ear pressure (MEP)...
February 1, 2018: Biomedical Optics Express
https://www.readbyqxmd.com/read/29504815/distortion-product-otoacoustic-emission-together-with-tympanometry-for-assessing-otitis-media-with-effusion-in-children
#20
Lei Jin, Keyong Li, Xiaoyan Li
OBJECTIVE: To investigate the diagnostic value of distortion product otoacoustic emission (DPOAE) together with tympanometry in assessing otitis media with effusion in children. METHODS: Three hundred and thirty-nine patients, who were diagnosed with obstructive sleep apnea-hypopnea syndrome (OSAHS) and prepared to undergo adenotonsillectomy and had a unilateral or bilateral type 'B' or 'C' tympanogram were enrolled in this study. Patients were divided into the following four groups: Group 1, type 'B' tympanogram with positive DPOAE; Group 2, type 'B' tympanogram with negative DPOAE; Group 3, type 'C' tympanogram with positive DPOAE and Group 4, type 'C' tympanogram with negative DPOAE...
March 5, 2018: Acta Oto-laryngologica
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