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https://www.readbyqxmd.com/read/28915151/analgesic-effects-of-locally-administered-ketorolac-based-analgesics-after-breast-surgery-a-meta-analysis-of-randomized-controlled-trials
#1
Jen-Yin Chen, I-Jung Feng, El-Wui Loh, Li-Kai Wang, Chao-Chun Lin, Ka-Wai Tam
OBJECTIVE: Reducing postoperative pain following breast surgery is crucial for rapid recovery and shortening hospital stay. Ketorolac, a nonsteroidal antiinflammatory drug, has been used as a postoperative analgesic in many surgical procedures. Here, we conducted a systemic review and meta-analysis on the efficacy of locally administered ketorolac-based analgesics in managing pain after breast surgery. METHODS: We searched the PubMed, Embase, Cochrane Library, Scopus, and ClinicalTrials...
September 14, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28914345/comparison-of-clinical-outcomes-between-open-and-thoracoscopic-repair-for-esophageal-atresia-with-tracheoesophageal-fistula-a-systematic-review-and-meta-analysis
#2
Yuhao Wu, Hongyu Kuang, Tiewei Lv, Chun Wu
OBJECTIVE: A meta-analysis was performed for a comparison of outcomes between open repair (OR) and thoracoscopic repair (TR) for esophageal atresia with tracheoesophageal fistula (EA with TEF). METHODS: Electronic databases, including PubMed, Cochrane Library, and Medline, were searched systematically for the literatures aimed mainly at comparing the therapeutic effects for EA with TEF administrated by OR and TR. Corresponding data sets were extracted and two reviewers independently assessed the methodological quality...
September 15, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28912048/effectiveness-and-safety-of-robotic-assisted-versus-laparoscopic-hepatectomy-for-liver-neoplasms-a-meta-analysis-of-retrospective-studies
#3
REVIEW
Lidong Hu, Liang Yao, Xiaofei Li, Penghui Jin, Kehu Yang, Tiankang Guo
This meta-analysis aimed to investigate the effectiveness and safety of RAH and LLR for liver neoplasms. A systematic search was performed in PubMed, EMbase, the Cochrane Library, Web of science, and China Biology Medicine disc up to July 2016 for studies that provided comparisons between the surgical outcomes of RAH and LLR for liver neoplasms. WMD, OR and 95% CI were calculated and data combined using the random-effect model. The quality of the evidence was assessed using GRADE methods. A total of 17 studies were included in the meta-analysis, in which 487 patients were in the RAH group and 902 patients were in the LLR group...
September 11, 2017: Asian Journal of Surgery
https://www.readbyqxmd.com/read/28906412/laparoscopic-nissen-total-versus-anterior-180%C3%A2-fundoplication-for-gastro-esophageal-reflux-disease-a-meta-analysis-and-systematic-review
#4
Xing Du, Ji-Min Wu, Zhi-Wei Hu, Feng Wang, Zhong-Gao Wang, Chao Zhang, Chao Yan, Mei-Ping Chen
BACKGROUND: Laparoscopic Nissen fundoplication (LNF) has been the gold standard for the surgical management of Gastro-esophageal reflux disease (GERD). Laparoscopic anterior 180° fundoplication (180° LAF) is reported to reduce the incidence of postoperative complications while obtaining similar control of reflux. The present meta-analysis was conducted to confirm the value of the 2 techniques. METHODS: PubMed, Medline, Embase, Cochrane Library, Springerlink, and China National Knowledge Infrastructure Platform databases were searched for randomized controlled trials (RCTs) comparing LNF and 180° LAF...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28904361/intrafascial-versus-interfascial-nerve-sparing-in-radical-prostatectomy-for-localized-prostate-cancer-a-systematic-review-and-meta-analysis
#5
Hong Weng, Xian-Tao Zeng, Sheng Li, Xiang-Yu Meng, Ming-Jun Shi, Da-Lin He, Xing-Huan Wang
The present study aimed to systematically evaluate the effectiveness and safety of the intrafascial and interfascial nerve sparing (ITR-NS and ITE-NS) radical prostatectomy. PubMed, Embase, and Cochrane Library databases were searched for eligible studies. Meta-analysis with random-effects model was performed. Six comparative trials were selected and embraced in this research, including one randomized controlled trial, three prospective comparative trials, and two retrospective comparative trials. With regard to perioperative parameters, no significant association of operative time, blood loss, transfusion rates, duration of catheterization, and hospital stay existed between ITR-NS and ITE-NS...
September 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28901001/-early-versus-traditional-postoperative-oral-feeding-in-patients-undergoing-elective-colorectal-surgery-a-meta-analysis-of-safety-and-efficacy
#6
Kun Zhang, Sirong Cheng, Qi Zhu, Zhenguo Han
OBJECTIVE: To compare the outcomes of early oral feeding (EOF) and the traditional oral feeding (TOF) in postoperative patients with colorectal cancer using Meta-analysis. METHODS: The databases of PubMed, SCI, Ovid, The Cochrane Library, CNKI, CBM, VIP and Wanfang Data were searched to collect randomized controlled trial (RCT) about EOF versus TOF in patients undergoing elective colorectal surgery. The retrieval time span was from inception to June 1, 2016. The studies were screened according to the inclusion and exclusion criteria...
September 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28888810/bystander-automated-external-defibrillator-use-and-clinical-outcomes-after-out-of-hospital-cardiac-arrest-a-systematic-review-and-meta-analysis
#7
REVIEW
Mathias J Holmberg, Mikael Vognsen, Mikkel S Andersen, Michael W Donnino, Lars W Andersen
AIM: To systematically review studies comparing bystander automated external defibrillator (AED) use to no AED use in regard to clinical outcomes in out-of-hospital cardiac arrest (OHCA), and to provide a descriptive summary of studies on the cost-effectiveness of bystander AED use. METHODS: We searched Medline, Embase, the Web of Science, and the Cochrane Library for randomized trials and observational studies published before June 1, 2017. Meta-analyses were performed for patients with all rhythms, shockable rhythms, and non-shockable rhythms...
September 6, 2017: Resuscitation
https://www.readbyqxmd.com/read/28888775/simultaneous-versus-delayed-hepatectomy-for-synchronous-colorectal-liver-metastases-a-systematic-review-and-meta-analysis
#8
REVIEW
Paschalis Gavriilidis, Robert P Sutcliffe, James Hodson, Ravi Marudanayagam, John Isaac, Daniel Azoulay, Keith J Roberts
OBJECTIVE: This was a systematic review and meta-analysis to compare outcomes between patients undergoing simultaneous or delayed hepatectomy for synchronous colorectal liver metastases. BACKGROUND: The optimal strategy for treating liver disease among patients with resectable synchronous colorectal liver metastases (CRLM) is unclear. Simultaneous resection of primary tumour and liver metastases may improve patient experience by reducing the number of interventions...
September 7, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28882916/incidence-of-laboratory-confirmed-influenza-disease-among-infants-under-6-months-of-age-a-systematic-review
#9
Deshayne B Fell, Jeanene Johnson, Zohar Mor, Mark A Katz, Becky Skidmore, Kathleen M Neuzil, Justin R Ortiz, Niranjan Bhat
OBJECTIVES: The aim of this systematic review was to assess incidence rates of laboratory-confirmed influenza (LCI) outcomes among infants under 6 months of age. DESIGN: Systematic literature search and review of indexed studies in PubMed, EMBASE, the Cochrane Library and CINAHL Plus from inception to 19 April 2017. SETTING: Population-based estimates from community or hospital settings. PARTICIPANTS: Infants under 6 months of age...
September 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28881894/outcomes-following-the-main-treatment-options-in-patients-with-a-leaking-esophagus-a-systematic-literature-review
#10
S Persson, I Rouvelas, T Irino, L Lundell
Leakage from the esophagus and gastroesophageal junction can be lethal due to uncontrolled contamination of the mediastinum. The most predominant risk factors for the subsequent clinical outcome are the patients' delay as well as the delay of diagnosis. Two major therapeutic concepts have been advocated: either prompt closure of the leakage by insertion of a self-expandable metal stent (SEMS) or more traditionally, surgical exploration. The objective of this review is to carefully scrutinize the recent literature and assess the outcomes of these two therapeutic alternatives in the management of iatrogenic perforation-spontaneous esophageal rupture as separated from those with anastomotic leak...
December 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28881841/efficacy-of-epidermal-growth-factor-receptor-egfr-tyrosine-kinase-inhibitors-tkis-in-targeted-therapy-of-lung-squamous-cell-carcinoma-patients-with-egfr-mutation-a-pooled-analysis
#11
Jingqi Zhuang, Yongfeng Yu, Ziming Li, Shun Lu
PURPOSE: This pooled analysis aims to evaluate the efficacy of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) in lung squamous cell carcinoma with EGFR mutation. METHODS: Advanced stage (IIIB/IV) lung squamous cell carcinoma patients with EGFR mutations treated with EGFR-TKIs were extracted from the publications searched from the databases of EMBASE, Medline (Ovid SP), Web of Science, Cochrane library, PubMed Publisher, ASCO meeting abstract and Google Scholar before August 2016, or identified from the database of Shanghai Chest Hospital from July 2014 to August 2016...
August 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28881697/feasibility-of-laparoscopic-gastrectomy-for-elderly-gastric-cancer-patients-meta-analysis-of-non-randomized-controlled-studies
#12
REVIEW
Liang Zong, Aiwen Wu, Wenyue Wang, Jingyu Deng, Susumu Aikou, Hiroharu Yamashita, Masahiro Maeda, Masanobu Abe, Duonan Yu, Zhiwei Jiang, Yasuyuki Seto, Jiafu Ji
The aim of this meta-analysis was to determine the feasibility of laparoscopic gastrectomy (LG) for elderly gastric cancer patients by comparing laparoscopic and conventional open gastrectomies (OG). Comprehensive search of the PubMed, EMBASE, and Cochrane Library databases revealed nine non-randomized controlled studies that compared LG and OG in elderly gastric cancer patients We then analyzed dichotomous or continuous parameters using odds ratios (ORs) or weighted mean differences (WMDs). Overall survival was estimated using hazard ratios (HRs) with a fixed effects or random effects model...
August 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28881069/person-centred-discharge-education-following-coronary-artery-bypass-graft-a-critical-review
#13
Melanie Rushton, Michelle Howarth, Maria J Grant, Felicity Astin
AIMS AND OBJECTIVES: This critical review examines the extent that individualised education helps reduce depression, anxiety and improves self-care for people who've undergone Coronary Artery Bypass Graft surgery (CABG). BACKGROUND: Individualised discharge planning is increasingly important following cardiac surgery due to recurrent admissions as well as the issue of anxiety and depression, often due to lack of preparation. The hospital to home transition is fundamental in the recovery process...
September 7, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28881006/simple-aspiration-versus-intercostal-tube-drainage-for-primary-spontaneous-pneumothorax-in-adults
#14
REVIEW
Kristin V Carson-Chahhoud, Abel Wakai, Joseph Em van Agteren, Brian J Smith, Grainne McCabe, Malcolm P Brinn, Ronan O'Sullivan
BACKGROUND: For management of pneumothorax that occurs without underlying lung disease, also referred to as primary spontaneous pneumothorax, simple aspiration is technically easier to perform than intercostal tube drainage. In this systematic review, we seek to compare the clinical efficacy and safety of simple aspiration versus intercostal tube drainage for management of primary spontaneous pneumothorax. This review was first published in 2007 and was updated in 2017. OBJECTIVES: To compare the clinical efficacy and safety of simple aspiration versus intercostal tube drainage for management of primary spontaneous pneumothorax...
September 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28880729/outcomes-following-laparoscopic-versus-open-major-hepatectomy-a-meta-analysis
#15
Hongwei Xu, Fei Liu, Hongyu Li, Yonggang Wei, Bo Li
OBJECTIVE: The role of laparoscopic major hepatectomy (LMH) remains uncertain in current liver surgery. This meta-analysis aimed to compare surgical and oncological outcomes of LMH versus open major hepatectomy (OMH). METHODS: A systematic search was conducted in PubMed, Embase, and the Cochrane Library database to identify all relevant publications. The statistical analysis was performed using Review Manager version 5.3. Continuous variables were calculated by standardized mean differences (SMD) with 95% confidence interval (CI), whereas dichotomous variables were calculated by odds ratio (OR) with 95%CI...
September 7, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28879784/non-chemotherapy-drug-induced-neutropenia-an-update
#16
Emmanuel Andrès, Rachel Mourot-Cottet
To date, non-chemotherapy drug-induced severe neutropenia (neutrophil count of ≤0.5 x 10(9)/L) also called idiosyncratic drug-induced agranulocytosis is little discussed in the literature. In the present paper, we report and discuss the clinical data and management of this rare disorder. Areas covered: To do this, we carried out a review of the literature using PubMed database of the US National Library of Medicine. We also used data from the American Society of Hematology educational books, textbooks of Hematology and Internal medicine, and information gleaned from international meetings...
September 7, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28877947/influence-of-hospital-volume-on-nephrectomy-mortality-and-complications-a-systematic-review-and-meta-analysis-stratified-by-surgical-type
#17
Ray C J Hsu, Theodosia Salika, Jonathan Maw, Georgios Lyratzopoulos, Vincent J Gnanapragasam, James N Armitage
OBJECTIVES: The provision of complex surgery is increasingly centralised to high-volume (HV) specialist hospitals. Evidence to support nephrectomy centralisation however has been inconsistent. We conducted a systematic review and meta-analysis to determine the association between hospital case volumes and perioperative outcomes in radical nephrectomy, partial nephrectomy and nephrectomy with venous thrombectomy. METHODS: Medline, Embase and the Cochrane Library were searched for relevant studies published between 1990 and 2016...
September 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28877841/cognitive-behaviour-therapy-for-health-anxiety-in-medical-patients-champ-a-randomised-controlled-trial-with-outcomes-to-5-years
#18
Peter Tyrer, Paul Salkovskis, Helen Tyrer, Duolao Wang, Michael J Crawford, Simon Dupont, Sylvia Cooper, John Green, David Murphy, Georgina Smith, Sharandeep Bhogal, Shaeda Nourmand, Valentina Lazarevic, Gemma Loebenberg, Rachel Evered, Stephanie Kings, Antoinette McNulty, Yvonne Lisseman-Stones, Sharon McAllister, Kofi Kramo, Jessica Nagar, Steven Reid, Rahil Sanatinia, Katherine Whittamore, Gemma Walker, Aaron Philip, Hilary Warwick, Sarah Byford, Barbara Barrett
BACKGROUND: Health anxiety is an under-recognised but frequent cause of distress that is potentially treatable, but there are few studies in secondary care. OBJECTIVE: To determine the clinical effectiveness and cost-effectiveness of a modified form of cognitive-behaviour therapy (CBT) for health anxiety (CBT-HA) compared with standard care in medical outpatients. DESIGN: Randomised controlled trial. SETTING: Five general hospitals in London, Middlesex and Nottinghamshire...
September 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28867465/effect-of-gum-chewing-on-ameliorating-ileus-following-colorectal-surgery-a-meta-analysis-of-18-randomized-controlled-trials
#19
REVIEW
Qing Liu, Honglei Jiang, Dong Xu, Junzhe Jin
BACKGROUND AND OBJECTIVE: Chewing gum, as an alternative to sham feeding, had been shown to hasten the recovery of gut function following abdominal surgery. However, conclusions remained contradictory. We sought to conduct an updated meta-analysis to evaluate the efficacy of gum chewing in alleviating ileus following colorectal surgery. METHODS: We searched PubMed, EMBASE, and Cochrane Library Databases through February 2017 to identify randomized controlled trials (RCTs) evaluating the efficacy of the additional use of chewing gum following colorectal surgery...
August 31, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28864224/catheter-directed-therapy-as-a-treatment-for-submassive-pulmonary-embolism-a-meta-analysis
#20
Xiao-Fang Li, Cheng-Quan Wan, Xue-Gai He, Jia-Yong Qiu, Dan-Yang Li, Yu-Xia Sun, Yi-Min Mao
AIMS: Catheter-directed therapy (CDT) is included in the guidelines for diagnosing and treating massive pulmonary embolism. However, few studies have evaluated the efficacy of CDT as a treatment for submassive pulmonary embolism (SPE). Therefore, we used evidence-based medicine to evaluate the effectiveness and safety of CDT in treating SPE. METHODS: Search terms describing CDT in SPE and patients with intermediate pulmonary embolism were entered into the PubMed, Embase and Cochrane Library databases to identify relevant articles without language restrictions published between January 1990 and December 2016...
August 29, 2017: Life Sciences
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