keyword
MENU ▼
Read by QxMD icon Read
search

Late life depression

keyword
https://www.readbyqxmd.com/read/28444658/comparing-the-immune-genomic-effects-of-vilazodone-and-paroxetine-in-late-life-depression-a-pilot-study
#1
Harris Eyre, Prabha Siddarth, Natalie Cyr, Hongyu Yang, Steve Cole, Malcolm Forbes, Helen Lavretsky
Vilazodone is a novel antidepressant agent that combines selective serotonin (5-HT) reuptake inhibitor (SSRI) activity and 5-HT(1A) receptor partial agonist activity. A pilot study was conducted to compare vilazodone (novel compound) and paroxetine (gold standard) on antidepressant effects, tolerability, and inflammation and immune modulation. A 12-week, double-blind, randomized clinical trial was conducted with 56 nondemented older adults diagnosed with major depressive disorder (MDD). Between-group differences in mood, tolerability, and safety, as well as genomic markers of inflammation and immune modulation, were examined...
April 25, 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28441647/subjective-memory-in-a-national-sample-predicting-psychological-well-being
#2
Jacqueline A Mogle, Nikki Hill, Caroline McDermott
BACKGROUND: Individual perception of memory performance (i.e., subjective memory) is assessed using a variety of approaches. This article focuses on 2 such approaches: (1) self-comparison assessments that attempt to capture changes in memory ability over a period of time and (2) age-anchored comparisons that assess how an individual perceives their memory in relation to others their age. These different types of assessment may relate to psychological well-being differently due to the underlying mechanisms of assessment...
April 26, 2017: Gerontology
https://www.readbyqxmd.com/read/28435933/the-c677t-variant-in-mthfr-modulates-associations-between-brain-integrity-mood-and-cognitive-functioning-in-old-age
#3
Florence F Roussotte, Xue Hua, Katherine L Narr, Gary W Small, Paul M Thompson
INTRODUCTION: The C677T functional variant in the methylene-tetrahydrofolate reductase (MTHFR) gene leads to reduced enzymatic activity and elevated blood levels of homocysteine. Hyperhomocysteinemia has been linked with higher rates of cardiovascular diseases, cognitive decline, and late-life depression. METHODS AND MATERIALS: Here, 3D magnetic resonance imaging data was analyzed from 738 individuals (age: 75.5 ± 6.8 years; 438 men/300 women) including 173 Alzheimer's patients, 359 subjects with mild cognitive impairment, and 206 healthy older adults, scanned as part of the Alzheimer's Disease Neuroimaging Initiative (ADNI)...
April 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28434642/-late-life-depression-or-prodromal-alzheimer-s-disease-which-tools-for-the-differential-diagnosis
#4
A-I Gasser, V Salamin, S Zumbach
INTRODUCTION: Depression and Alzheimer's disease are both very frequent in elderly people. Cognitive deficits are the hallmark of Alzheimer's disease, but they are also common in depressed elderly people who often present cognitive deficits such as memory, attention and executive function problems. On the other hand, people with early Alzheimer's disease demonstrate emotional and behavioral disorders generally encountered in depression such as loss of energy, apathy, mood disorder, and irritability...
April 20, 2017: L'Encéphale
https://www.readbyqxmd.com/read/28432781/cognitive-functioning-and-emotion-processing-in-breast-cancer-survivors-and-controls-an-erp-pilot-study
#5
Janine Wirkner, Mathias Weymar, Andreas Löw, Carmen Hamm, Anne-Marie Struck, Clemens Kirschbaum, Alfons O Hamm
Diagnosis and treatment of breast cancer is a very emotionally aversive and stressful life event, which can lead to impaired cognitive functioning and mental health. Breast cancer survivors responding with repressive emotion regulation strategies often show less adaptive coping and adverse outcomes. We investigated cognitive functioning and neural correlates of emotion processing using ERPs. Self-report measures of depression, anxiety, and fatigue, as well as hair cortisol as an index of chronic stress, were assessed...
April 22, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28424070/antidepressant-use-and-cognitive-decline-in-community-dwelling-elderly-people-the-three-city-cohort
#6
Isabelle Carrière, Joanna Norton, Amandine Farré, Marilyn Wyart, Christophe Tzourio, Pernelle Noize, Karine Pérès, Annie Fourrier-Réglat, Karen Ritchie, Marie Laure Ancelin
BACKGROUND: Cognitive impairment is very common in late-life depression, principally affecting executive skills and information processing speed. The aim of the study was to examine the effect of antidepressant treatment on cognitive performances over a 10-year period. METHODS: The community-based cohort included 7381 participants aged 65 years and above. Five cognitive domains (verbal fluency, psychomotor speed, executive function, visuospatial skills and global cognition) were assessed up to five times over 10 years of follow-up...
April 19, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28421866/chronic-pain-and-psychological-distress-among-older-adults
#7
Alex Bierman, Yeonjung Lee
This research examines whether unobserved time-stable influences confound the association between chronic pain and psychological distress in older adults as well as how race and ethnicity combine with subjective social status (SSS) to modify the association. In a nationally representative longitudinal survey, holistically controlling for unobserved time-stable influences using fixed-effects models substantially reduces the pain-depression relationship and eliminates the overall pain-anxiety relationship. The association with depression is stronger for Black and Hispanic elders, illustrating a process of double-jeopardy...
January 1, 2017: Research on Aging
https://www.readbyqxmd.com/read/28418079/loneliness-and-cardiovascular-disease-and-the-role-of-late-life-depression
#8
Annette Hegeman, Natasja Schutter, Hannie Comijs, Tjalling Holwerda, Jack Dekker, Max Stek, Roos van der Mast
OBJECTIVE: Loneliness and depression have a strong reciprocal influence, and both predict adverse health outcomes at old age. Therefore, this study examines whether loneliness is associated with the presence of cardiovascular diseases taking into account the role of late-life depression. METHODS: Cross-sectional data of 477 older adults in the Netherlands Study of Depressed Older Persons were used. Logistic regression analysis was performed to examine the relation between loneliness and cardiovascular disease...
April 18, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28412979/physical-exercise-for-late-life-depression-effects-on-cognition-and-disability
#9
Francesca Neviani, Martino Belvederi Murri, Chiara Mussi, Federico Triolo, Giulio Toni, Elisabetta Simoncini, Ferdinando Tripi, Marco Menchetti, Silvia Ferrari, Graziano Ceresini, Alessandro Cremonini, Marco Bertolotti, Giovanni Neri, Salvatore Squatrito, Mario Amore, Stamatula Zanetidou, Mirco Neri
BACKGROUND: Late-life depression is often associated with cognitive impairments and disability, which may persist even after adequate antidepressant drug treatment. Physical exercise is increasingly recognized as an effective antidepressant agent, and may exert positive effects on these features too. However, few studies examined this issue, especially by comparing different types of exercises. METHODS: We performed secondary analyses on data from the Safety and Efficacy of Exercise for Depression in Seniors study, a trial comparing the antidepressant effectiveness of sertraline (S), sertraline plus thrice-weekly non-progressive exercise (S+NPE), and sertraline plus thrice-weekly progressive aerobic exercise (S+PAE)...
April 17, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28409063/a-practical-approach-to-detection-and-treatment-of-depression-in-parkinson-disease-and-dementia
#10
REVIEW
Zahra Goodarzi, Zahinoor Ismail
PURPOSE OF REVIEW: To review the available evidence for the detection and management of depression in Parkinson disease (PD) and dementia. RECENT FINDINGS: Depression is a common comorbidity in those with PD or dementia, and leads to increased morbidity. There are several available and accurate tools for the detection of depression in PD (e.g., Geriatric Depression Scale) and dementia (e.g., Cornell Scale for Depression in Dementia). Treatment of depression depends on patient preference, severity of depression, comorbidities, and available resources...
April 2017: Neurology. Clinical Practice
https://www.readbyqxmd.com/read/28403622/amyloid-positivity-using-18f-flutemetamol-pet-and-cognitive-deficits-in-nondemented-community-dwelling-older-adults
#11
Dustin B Hammers, Taylor J Atkinson, Bonnie C A Dalley, Kayla R Suhrie, Kevin P Horn, Kelli M Rasmussen, Britney E Beardmore, Lance D Burrell, Kevin Duff, John M Hoffman
Little research exists examining the relationship between beta-amyloid neuritic plaque density via [18F]flutemetamol binding and cognition; consequently, the purpose of the current study was to compare cognitive performances among individuals having either increased amyloid deposition (Flute+) or minimal amyloid deposition (Flute-). Twenty-seven nondemented community-dwelling adults over the age of 65 underwent [18F]flutemetamol amyloid-positron emission tomography imaging, along with cognitive testing using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and select behavioral measures...
January 1, 2017: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/28399220/associations-of-fat-and-muscle-tissue-with-cognitive-status-in-older-adults-the-ages-reykjavik-study
#12
Peggy J J Spauwen, Rachel A Murphy, Pálmi V Jónsson, Sigurdur Sigurdsson, Melissa E Garcia, Gudny Eiriksdottir, Martin P J van Boxtel, Oscar L Lopez, Vilmundur Gudnason, Tamara B Harris, Lenore J Launer
Background/Objective: studies on the association of dementia with specific body composition (BC) components are scarce. Our aim was to investigate associations of BC measures with different levels of cognitive function in late-life. Methods: we studied 5,169 participants (mean age 76 years, 42.9% men) in the AGES-Reykjavik Study of whom 485 (9.4%) were diagnosed with mild cognitive impairment (MCI) and 307 (5.9%) with dementia. Visceral fat, abdominal and thigh subcutaneous fat, and thigh muscle were assessed by computed tomography...
March 1, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28393076/subthreshold-depression-and-clinically-significant-depression-in-an-italian-population-of-70-74-year-olds-prevalence-and-association-with-perceptions-of-self
#13
Roberta Vaccaro, Paola Borrelli, Simona Abbondanza, Annalisa Davin, Letizia Polito, Mauro Colombo, Silvia Francesca Vitali, Simona Villani, Antonio Guaita
Estimates of depressive disorders in the elderly vary depending on how cases are defined. We estimated the prevalence of subthreshold depression (SD) and clinically significant depression (D) in a population of 70-74-year-olds. We also looked for associations with sociodemographic factors and perceptions of self. Participants underwent a multidimensional assessment (social, medical, and neuropsychological). The estimated prevalence of SD was 15.71% (95% CI: 13.70-17.72), while that of D was 5.58% (95% CI: 4...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28390440/prevalence-of-and-risk-factors-for-minor-and-major-depression-among-community-dwelling-older-adults-in-taiwan
#14
Chi-Shin Wu, Shu-Han Yu, Chun-Yi Lee, Han-Yun Tseng, Yen-Feng Chiu, Chao Agnes Hsiung
BACKGROUND: This study was conducted to estimate prevalence rates and risk factors for late-life depression in a large nationwide representative sample from Taiwan. METHODS: A total of 5,664, randomly sampled individuals aged ≥55 years were enrolled. Clinically, relevant depressive symptoms were classified using the Center for Epidemiological Studies Depression Scale (CES-D score ≥16), and major depression was confirmed using the Primary Care Evaluation of Mental Disorders...
April 9, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28382870/late-versus-early-onset-depression-in-elderly-patients-vascular-risk-and-cognitive-impairment
#15
Abdelhamid H Hashem, Maged Al-Adrousy Gomaa, Mohamed Nasr Elden Sadek, Ola Osama Khalaf
BACKGROUND: Three-quarters of patients with major depressive disorder have late-onset depression. Late-onset depression is more often associated with cognitive impairment than early-onset depression and evidences showed a relationship between vascular factors and late-life depression. OBJECTIVES: To compare cognitive functions between late-onset (≥60 years) and early-onset (<60 years) depression in elderly patients and to highlight the effect of vascular risk factors in elderly patients with late and early onset depression...
April 4, 2017: Current Aging Science
https://www.readbyqxmd.com/read/28380710/the-reduction-of-public-and-internalized-stigma-in-late-life-depression
#16
Symone A McKinnon, Kyaien O Conner, Rosalyn Roker, Chris J Ward, Charlotte Brown
Innovative strategies are needed to reduce the impact of stigma as a barrier to mental health services for older adults living with a mental illness. The purpose of this brief report was to examine the impact of a 3-month peer educator (PE) intervention on stigma reduction in a sample of depressed older adults. PEs are individuals of similar age, and racial and socioeconomic backgrounds who have been previously treated for depression, and are trained to provide support and education to depressed individuals within their community...
January 1, 2017: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/28379498/association-of-anxiety-symptom-clusters-with-sleep-quality-and-daytime-sleepiness
#17
Christine E Gould, Adam P Spira, Victoria Liou-Johnson, Erin Cassidy-Eagle, Makoto Kawai, Nehjla Mashal, Ruth O'Hara, Sherry A Beaudreau
Objectives: To better understand links between anxiety and sleep disturbances in older adults, we examined the association of different phenotypic presentations of anxiety (i.e., affective, cognitive, and somatic clusters) with global sleep quality and daytime sleepiness. Methods: 109 community-dwelling adults aged 66-92 years old (57% female) completed assessments of global sleep quality (Pittsburgh Sleep Quality Index), daytime sleepiness (Epworth Sleepiness Scale), affective anxiety symptoms (Geriatric Anxiety Scale (GAS) affective subscale), cognitive anxiety symptoms (GAS cognitive subscale), and somatic anxiety symptoms (GAS somatic subscale)...
April 3, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28369380/late-life-depression-and-the-association-with-multimorbidity-and-polypharmacy-a-cross-sectional-study
#18
Floor Holvast, Bernard A van Hattem, Judith Sinnige, François Schellevis, Katja Taxis, Huibert Burger, Peter F M Verhaak
Background.: Late-life depression often coincides with chronic somatic diseases and, consequently, with polypharmacy, which may complicate medical treatment. Objective.: To determine the associations between patients diagnosed with late-life depression in primary care and multimorbidity and polypharmacy. Methods.: This cross-sectional observational study was performed using 2012 primary care data. Depressed patients aged ≥60 years were compared to age and gender matched patients diagnosed with other psychological diagnoses and mentally healthy controls...
March 23, 2017: Family Practice
https://www.readbyqxmd.com/read/28365469/the-impact-of-frailty-on-depressive-disorder-in-later-life-findings-from-the-netherlands-study-of-depression-in-older-persons
#19
R M Collard, M H L Arts, A H Schene, P Naarding, R C Oude Voshaar, H C Comijs
BACKGROUND: Physical frailty and depressive symptoms are reciprocally related in community-based studies, but its prognostic impact on depressive disorder remains unknown. METHODS: A cohort of 378 older persons (≥60 years) suffering from a depressive disorder (DSM-IV criteria) was reassessed at two-year follow-up. Depressive symptom severity was assessed every six months with the Inventory of Depressive Symptomatology, including a mood, motivational, and somatic subscale...
January 24, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28362229/late-chronotypes-are-associated-with-neoadjuvant-chemotherapy-induced-nausea-and-vomiting-in-women-with-breast-cancer
#20
Kwang-Min Lee, Doo-Young Jung, Heesung Hwang, Won-Hyoung Kim, Joo-Young Lee, Tae-Yong Kim, Seock-Ah Im, Kyung-Hun Lee, David Spiegel, Bong-Jin Hahm
Neoadjuvant chemotherapy, that is, the administration of chemotherapy before surgery, has been commonly used for locally advanced breast cancer to improve the surgical outcomes and increase the opportunity for breast-conserving therapy. Women with breast cancer often receive an anthracycline-based regimen as the neoadjuvant chemotherapy, which is associated with a high risk of emesis. Despite the development of novel antiemetics, chemotherapy-induced nausea and vomiting (CINV) has been commonly reported as a major adverse effect, affecting the quality of life of the patients...
2017: Chronobiology International
keyword
keyword
22229
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"