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Late life depression

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https://www.readbyqxmd.com/read/28641215/worry-and-cognitive-control-predict-course-trajectories-of-anxiety-in-older-adults-with-late-life-depression
#1
P Spinhoven, D C van der Veen, R C Oude Voshaar, H C Comijs
BACKGROUND: Many older adults with depressive disorder manifest anxious distress. This longitudinal study examines the predictive value of worry as a maladaptive cognitive emotion regulation strategy, and resources necessary for successful emotion regulation (i.e., cognitive control and resting heart rate variability [HRV]) for the course of anxiety symptoms in depressed older adults. Moreover, it examines whether these emotion regulation variables moderate the impact of negative life events on severity of anxiety symptoms...
May 19, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28629899/high-adherence-to-a-mediterranean-diet-and-lower-risk-of-frailty-among-french-older-adults-community-dwellers-results-from-the-three-city-bordeaux-study
#2
Berna Rahi, Soufiane Ajana, Maturin Tabue-Teguo, Jean-François Dartigues, Karine Peres, Catherine Feart
BACKGROUND & AIMS: Mediterranean diet (MeDi) is considered as a key component for healthy aging, including prevention of age-related disability, while its association with frailty, independent of disability has never been assessed. Our objective was to investigate the relation between MeDi adherence and frailty incidence among persons aged ≥75 years participating at the prospective population-based French Three-City Study. METHODS: The study sample consisted of 560 initially non-frail participants of the Three-City-Bordeaux center, seen at the 2009-2010 follow-up, and re-examined two years later...
May 31, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28624531/the-short-to-mid-term-symptom-prevalence-of-dumping-syndrome-after-primary-gastric-bypass-surgery-and-its-impact-on-health-related-quality-of-life
#3
Marloes Emous, Bruce H R Wolffenbuttel, Eric Totté, André P van Beek
BACKGROUND: Early and late dumping are complications of gastric bypass surgery. Early dumping occurs within an hour after eating, when the emptying of food into the small intestine triggers rapid fluid shifts into the intestinal lumen and the release of gastrointestinal hormones, resulting in gastrointestinal and vasomotor symptoms. Late dumping occurs between 1 and 3 hours after carbohydrate ingestion and is caused by an exaggerated insulin release, resulting in hypoglycemia. Almost no data are currently available on the prevalence of early and late dumping or their impact on health-related quality of life (QoL)...
April 28, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28623080/increased-constitutive-nitric-oxide-production-by-whole-body-periodic-acceleration-ameliorates-alterations-in-cardiomyocytes-associated-with-utrophin-dystrophin-deficiency
#4
Jose R Lopez, Juan Kolster, Rui Zhang, Jose Adams
Duchenne Muscular Dystrophy (DMD) cardiomyopathy is a progressive lethal disease caused by the lack of the dystrophin protein in the heart. The most widely used animal model of DMD is the dystrophin-deficient mdx mouse; however, these mice exhibit a mild dystrophic phenotype with heart failure only late in life. In contrast, mice deficient for both dystrophin and utrophin (mdx/utrn(-/-), or dKO) can be used to model severe DMD cardiomyopathy where pathophysiological indicators of heart failure are detectable by 8-10weeks of age...
June 13, 2017: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/28615661/increased-levels-of-ascorbic-acid-in-the-cerebrospinal-fluid-of-cognitively-intact-elderly-patients-with-major-depression-a-preliminary-study
#5
Kenji Hashimoto, Tamaki Ishima, Yasunori Sato, Davide Bruno, Jay Nierenberg, Charles R Marmar, Henrik Zetterberg, Kaj Blennow, Nunzio Pomara
Major depressive disorder (MDD) in the elderly is a risk factor for dementia, but the precise biological basis remains unknown, hampering the search for novel biomarkers and treatments. In this study, we performed metabolomics analysis of cerebrospinal fluid (CSF) from cognitively intact elderly patients (N = 28) with MDD and age- and gender-matched healthy controls (N = 18). The CSF levels of 177 substances were measured, while 288 substances were below the detection limit. Only ascorbic acid was significantly different, with higher levels in the MDD group at baseline...
June 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28612654/a-qualitative-comparison-of-dsm-depression-criteria-to-language-used-by-older-church-going-african-americans
#6
Esther Akinyemi, Daphne C Watkins, Janet Kavanagh, Vicki Johnson-Lawrence, Shana Lynn, Helen C Kales
OBJECTIVE: Depression in late life is associated with substantial suffering, disability, suicide risk, and decreased health-related quality of life. According to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), a depression diagnosis is derived from a constellation of symptoms that may be described differently by different people. For example, the DSM language may be inadequate in capturing these symptoms in certain populations such as African-Americans, whose rates of depression misdiagnosis is high...
June 14, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28603719/prospective-study-of-quality-of-life-after-lung-cancer-resection
#7
Kathleen G Hopkins, Peter F Ferson, Manisha R Shende, Neil A Christie, Matthew J Schuchert, Arjun Pennathur
BACKGROUND: Surgical resection with curative-intent remains the gold standard for clinically operable early-stage non-small cell lung cancer (NSCLC). This goal can be accomplished using a minimally invasive option, e.g., video assisted thoracic surgery (VATS) or standard thoracotomy. Surgical techniques continue to evolve and few studies have compared the QOL of patients managed with these procedures using current approaches. The primary goal of this study was to investigate differences between patients managed surgically via VATS compared to thoracotomy with respect to ratings of chronic pain, anxiety/depression and quality of life (QOL)...
May 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28602383/stress-and-late-life-depression
#8
EDITORIAL
Christopher C Abbott, Mohamad Khafaja
No abstract text is available yet for this article.
May 17, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28592136/relationship-of-depression-with-executive-functions-and-visuospatial-memory-in-elderly
#9
Monika Klojčnik, Voyko Kavcic, Karin Bakracevic Vukman
Cognitive deficits are a potential part of the clinical picture of depression, especially when it comes to late-life depression. The present study was carried out to establish whether distinctive cognitive deficiencies can be linked with depression in the late-life period, especially in executive functioning, working memory, and visuospatial memory. Our sample consisted of 71 seniors in the age range between 69 and 85 years. A battery of neurocognitive tests was used, including tests of executive functioning (Trail Making Test [TMT], part B, Stroop color word test, semantic word fluency test, and partially Rey-Osterrieth Complex Figure test [ROCF]), tests of attention and working memory (TMT, part A and digit span), and test of visuospatil ability and memory (ROCF)...
January 1, 2017: International Journal of Aging & Human Development
https://www.readbyqxmd.com/read/28588453/refining-the-role-of-5-ht-in-postnatal-development-of-brain-circuits
#10
REVIEW
Anne Teissier, Mariano Soiza-Reilly, Patricia Gaspar
Changing serotonin (5-hydroxytryptamine, 5-HT) brain levels during critical periods in development has long-lasting effects on brain function, particularly on later anxiety/depression-related behaviors in adulthood. A large part of the known developmental effects of 5-HT occur during critical periods of postnatal life, when activity-dependent mechanisms remodel neural circuits. This was first demonstrated for the maturation of sensory brain maps in the barrel cortex and the visual system. More recently this has been extended to the 5-HT raphe circuits themselves and to limbic circuits...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28586377/psychometric-properties-of-a-power-mobility-caregiver-assistive-technology-outcome-measure
#11
W Ben Mortenson, Louise Demers, Paula W Rushton, Claudine Auger, François Routhier, William C Miller
Caregiver burnout is a serious concern among informal caregivers, especially for those who provide care to individuals with more severe limitations such as power mobility users. The Power Wheelchair Caregiver Assistive Technology Outcome Measure tool measures device specific and overall burden experienced by informal caregivers of power mobility users. A one-month, test-retest study was conducted to examine the reliability, internal consistency, and construct validity of the Power Wheelchair Caregiver Assistive Technology Outcome Measure...
2017: PloS One
https://www.readbyqxmd.com/read/28585568/brain-tissue-pulsatility-is-increased-in-mid-life-depression-a-comparative-study-using-ultrasound-tissue-pulsatility-imaging
#12
Thomas Desmidt, Bruno Brizard, Paul-Armand Dujardin, Redouane Ternifi, Jean-Pierre Réméniéras, Frédéric Patat, Frédéric Andersson, Jean-Philippe Cottier, Emilie Vierron, Valérie Gissot, Kang Kim, Howard Aizenstein, Wissam El-Hage, Vincent Camus
Cerebrovascular disease (CVD) is consistently associated with late-life depression but poorly documented in midlife depression. It can be hypothesized that the relatively low sensitivity of conventional neuroimaging techniques does not allow the detection of subtle CVD in midlife depression. We used Tissue Pulsatility Imaging (TPI), a novel ultrasound (US) neuroimaging technique that has demonstrated good sensitivity to detect changes in the pulsatility of small brain volumes, to identify early and subtle changes in brain vascular function in midlife depression...
June 6, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28578453/prenatal-care-associations-with-prenatal-depressive-symptoms-and-social-support-in-low-income-urban-women
#13
Abbey C Sidebottom, Wendy L Hellerstedt, Patricia A Harrison, Rhonda J Jones-Webb
We examined associations of depressive symptoms and social support with late and inadequate prenatal care in a low-income urban population. The sample was prenatal care patients at five community health centers. Measures of depressive symptoms, social support, and covariates were collected at prenatal care entry. Prenatal care entry and adequacy came from birth certificates. We examined outcomes of late prenatal care and less than adequate care in multivariable models. Among 2341 study participants, 16% had elevated depressive symptoms, 70% had moderate/poor social support, 21% had no/low partner support, 37% had late prenatal care, and 29% had less than adequate prenatal care...
June 3, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28566108/cognitive-performance-of-community-dwelling-oldest-old-individuals-with-major-depression-the-piet%C3%A3-study
#14
Filipi Leles da Costa Dias, Antônio Lúcio Teixeira, Henrique Cerqueira Guimarães, Maira Tonidandel Barbosa, Elisa de Paula França Resende, Rogério Gomes Beato, Karoline Carvalho Carmona, Paulo Caramelli
BACKGROUND: Individuals with late-life depression (LLD) may present cognitive symptoms. We sought to determine whether a brief cognitive battery (BCB) could identify cognitive and functional deficits in oldest-old individuals with LLD and a low level of education. METHODS: We evaluated 639 community-dwelling individuals aged 75+ years in Caeté (MG), Brazil. We used the MINI and GDS-15 to diagnose major depression and evaluate its severity, respectively. The cognitive evaluation comprised the Mini-Mental State Examination (MMSE), BCB, clock-drawing test, category fluency test (animals) and Pfeffer's Functional Activities Questionnaire (FAQ)...
June 1, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28564681/association-of-microvascular-dysfunction-with-late-life-depression-a-systematic-review-and-meta-analysis
#15
Marnix J M van Agtmaal, Alfons J H M Houben, Frans Pouwer, Coen D A Stehouwer, Miranda T Schram
Importance: The etiologic factors of late-life depression are still poorly understood. Recent evidence suggests that microvascular dysfunction is associated with depression, which may have implications for prevention and treatment. However, this association has not been systematically reviewed. Objective: To examine the associations of peripheral and cerebral microvascular dysfunction with late-life depression. Data Sources: A systematic literature search was conducted in MEDLINE and EMBASE for and longitudinal studies published since inception to October 16, 2016, that assessed the associations between microvascular dysfunction and depression...
May 31, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28556801/heterogeneous-trajectories-of-physical-and-mental-health-in-late-middle-age-importance-of-life-course-socioeconomic-positions
#16
Eunsun Kwon, Sojung Park
Drawing on life course and cumulative disadvantage theory, this study examines heterogeneous trajectories of functional limitations and depressive symptoms among late middle-aged individuals. This study used prospective data from 6010 adults, 51 to 64 years old, collected over a 12-year-period from the Health and Retirement Study. Considering the empirical proposition that several physical and mental trajectories may exist, Latent Class Growth Modeling was used. Five heterogeneous patterns of joint trajectories (Relatively healthy, Moderately improving, Steadily deteriorating, Steeply deteriorating, and Persistently high comorbid) were identified...
May 30, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28556687/effects-of-adolescent-sport-practice-on-health-outcomes-of-adult-amateur-endurance-cyclists-adulthood-is-not-too-late-to-start
#17
Diego Munguia-Izquierdo, Carmen Mayolas-Pi, Carlos Peñarrubia-Lozano, Federico Paris-Garcia, Javier Bueno-Antequera, Miguel Angel Oviedo-Caro, Alejandro Legaz-Arrese
BACKGROUND: We investigated the effects of adolescent sport practice on the training, performance, and health outcomes of adult amateur endurance cyclists and compared health outcomes of 3 adult groups: amateur endurance cyclists who practiced sports during adolescence, amateur endurance cyclists who did not practice sports during adolescence, and inactive individuals. METHODS: In 859 (751 men, 108 women) adult cyclists and 718 inactive subjects (307 men, 411 women), we examined adolescent sport practice, current training status, quality of life, quality of sleep, anxiety and depression and cardiometabolic risk: body mass index, physical activity, physical fitness, adherence to Mediterranean diet, and alcohol and tobacco consumption...
May 30, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28553816/heterogeneous-trajectories-of-depressive-symptoms-in-late-middle-age-critical-period-accumulation-and-social-mobility-life-course-perspectives
#18
Eunsun Kwon, BoRin Kim, Hyunjoo Lee, Sojung Park
OBJECTIVE: This study investigated patterns of depressive symptoms and whether socioeconomic status (SES) across the life course affects these trajectories using the critical period, accumulation, and social mobility models. METHOD: This study uses data from 8,532 adults, age 51 to 64, collected over 12 years from the Health and Retirement Study (observations = 25,887). A latent class analysis was performed to examine distinct depressive symptom trajectories; life course models were studied with multinomial logistic regression...
April 1, 2017: Journal of Aging and Health
https://www.readbyqxmd.com/read/28550256/cortical-thickness-and-depressive-symptoms-in-cognitively-normal-individuals-the-mayo-clinic-study-of%C3%A2-aging
#19
Anna Pink, Scott A Przybelski, Janina Krell-Roesch, Gorazd B Stokin, Rosebud O Roberts, Michelle M Mielke, David S Knopman, Clifford R Jack, Ronald C Petersen, Yonas E Geda
Altered cortical thickness has been observed in aging and various neurodegenerative disorders. Furthermore, reduced hippocampal volume has been reported in late-life depression. Even mild depressive symptoms are common in the elderly. However, little is known about the structural MRI measures of depressive symptoms in normal cognitive aging. Thus we sought to examine the association between depressive symptoms with cortical thickness and hippocampal volume as measured by brain MRI among community-dwelling participants...
May 25, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28543407/assessing-bipolar-disorder-in-the-older-adult-the-geri-bd-toolbox
#20
Patricia Marino, Herbert C Schulberg, Ariel G Gildengers, Benoit H Mulsant, Martha Sajatovic, Laszlo Gyulai, Rayan K Aljurdi, Laurie Davan Evans, Samprit Banerjee, Ruben C Gur, Robert C Young
INTRODUCTION: The evidence base regarding characteristics of older adults with bipolar disorder (BD) remains limited. The NIH-funded multicenter study Acute Pharmacotherapy of Late-Life Mania (GERI-BD) assessed various clinical domains before and during mood stabilizer treatment in older adults participating in a 9-week, double-blind randomized controlled trial. We describe the rationale for selecting these instruments. METHODS: Domains and instruments were selected on the basis of the study design and the participants...
May 22, 2017: International Journal of Geriatric Psychiatry
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