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Late life depression

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https://www.readbyqxmd.com/read/28528350/prevalence-and-impact-of-severe-fatigue-in-adolescent-and-young-adult-cancer-patients-in-comparison-with-population-based-controls
#1
Hanneke Poort, Suzanne E J Kaal, Hans Knoop, Rosemarie Jansen, Judith B Prins, Eveliene Manten-Horst, Petra Servaes, Olga Husson, Winette T A van der Graaf
PURPOSE: The current study determined the prevalence of severe fatigue in adolescent and young adult (AYA) cancer patients (aged 18-35 years at diagnosis) consulting a multidisciplinary AYA team in comparison with gender- and age-matched population-based controls. In addition, impact of severe fatigue on quality of life and correlates of fatigue severity were examined. METHODS: AYAs with cancer (n = 83) completed questionnaires including the Checklist Individual Strength (CIS-fatigue), Quality of Life (QoL)-Cancer Survivor, Hospital Anxiety and Depression Scale (reflecting psychological distress), and the Cancer Worry Scale (reflecting fear of cancer recurrence or progression)...
May 20, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28527907/behavioral-and-cognitive-impact-of-early-life-stress-insights-from-an-animal-model
#2
Hesong Liu, Fatin Atrooz, Ankita Salvi, Samina Salim
BACKGROUND: Children subjected to traumatic events during childhood are reported to exhibit behavioral and cognitive deficits later in life, often leading to post-traumatic stress disorder (PTSD) and major depression. Interestingly, some children continue to remain normal despite being exposed to the same risk factors. These trauma-related behavioral and cognitive profiles across different stages of life are not well understood. Animal studies can offer useful insights. OBJECTIVE: The goal of this study was to determine the impact of early life exposure to traumatic events on behavioral and cognitive profile in rats by tracking the behavior of each rat at different ages...
May 17, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28527083/shared-mechanisms-of-epilepsy-migraine-and-affective-disorders
#3
Davide Zarcone, Simona Corbetta
Since the nineteenth century several clinical features have been observed in common between migraine and epilepsy (such as episodic attacks, triggering factors, presence of aura, frequent familiarity), but only in recent years researchers have really engaged in finding a common pathogenic mechanism. From studies of disease incidence, we understand how either migraine among patients with epilepsy or epilepsy among migraine patients are more frequent than in the general population. This association may result from a direct causality, by the same environmental risk factors and/or by a common genetic susceptibility...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28525728/response-to-letter-regarding-canmat-recommendations-for-the-pharmacological-treatment-of-late-life-depression
#4
Raymond W Lam, Zahinoor Ismail, Glenda M MacQueen, Roumen V Milev, Sagar V Parikh, Arun V Ravindran, Sidney H Kennedy
No abstract text is available yet for this article.
May 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28525727/some-of-the-canmat-recommendations-for-the-pharmacological-treatment-of-late-life-depression-are-not-congruent-with-available-evidence-or-expert-opinion
#5
Daniel Blumberger, David Conn, John S Kennedy, Benoit H Mulsant, Bruce G Pollock, Kiran Rabheru, Mark J Rapoport, Dallas Seitz
No abstract text is available yet for this article.
May 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28521620/depression-inflammation-and-physiological-risk-in-late-life-a-national-longitudinal-study
#6
Aniruddha Das
This nationally representative study queried effects of community dwelling older adults' depression and inflammation at baseline on over-time changes in surrogate markers of their cardiometabolic risk. Data were from the 2005-2006 and 2010-2011 waves of the U.S. National Social Life, Health, and Aging Project. Inflammation was indicated by C-reactive protein and depression by the CES-D scale. Cardiometabolic markers included hemoglobin A1c and systolic BP. Lagged dependent variable models were used to examine effects...
2017: Biodemography and Social Biology
https://www.readbyqxmd.com/read/28521552/unmet-needs-in-the-depressed-primary-care-elderly-and-their-relation-to-severity-of-depression-results-from-the-agemoode-study
#7
Sophie Alltag, Janine Stein, Alexander Pabst, Siegfried Weyerer, Jochen Werle, Wolfgang Maier, Lisa Miebach, Martin Scherer, Anne Stark, Birgitt Wiese, Silke Mamone, Hans-Helmut König, Jens-Oliver Bock, Steffi G Riedel-Heller
OBJECTIVES: This study aims at examining the distribution of unmet environmental, physical, social and psychological care needs in a sample of the oldest old primary care patients with different levels of depression severity. Furthermore, the objective of this study was to analyze the association between specific unmet care needs and severity of depression. METHOD: The sample of patients aged 75 years (n = 202) and more was derived from the multicenter prospective cohort study AgeMooDe ('Late-life depression in primary care: Needs, health care utilization and costs')...
May 19, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28516827/bold-activation-of-the-ventromedial-prefrontal-cortex-in-patients-with-late-life-depression-and-comparison-participants
#8
Akshya Vasudev, Michael J Firbank, Joseph S Gati, Emily Ionson, Alan J Thomas
The ventromedial prefrontal cortex's (vMPFC) role in regulating emotions in late life depression (LLD) remains unclarified. We assessed vMPFC activation in an emotional valence blood oxygenation level-dependent (BOLD) functional magnetic neuroimaging (fMRI) task and related the findings to extent of white matter hyperintensities (WMH). Sixteen participants with mild to moderate LLD were compared to 14 similar aged comparison participants. Participants in the scanner viewed words matched for length and arousal, indicated the perceived valence by pressing one of the three buttons i...
May 18, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28514459/late-life-depression-and-the-prodromes-of-dementia
#9
David Carl Steffens
No abstract text is available yet for this article.
May 17, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28510288/the-relationship-of-physiopsychosocial-factors-and-spiritual-well-being-in-elderly-residents-implications-for-evidence-based-practice
#10
Yi-Heng Chen, Li-Chan Lin, Li-Lan Chuang, Mei-Li Chen
BACKGROUND: Older adults in residential settings frequently suffer from functional decline, mental illness, and social isolation, which make them more vulnerable to spiritual distress. However, empirical evidence of the interrelationships between physiopsychosocial variables and spiritual well-being are still lacking, limiting the application of the biopsychosocial-spiritual model in institutional healthcare practice. AIMS: To explain the mechanisms by which these variables are linked, this cross-sectional study tested a causal model of predictors of spiritual well-being among 377 institutionalized older adults with disability using a structural equation modeling approach...
May 16, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28491917/understanding-the-burden-experienced-by-caregivers-of-older-adults-who-use-a-powered-wheelchair-a-cross-sectional-study
#11
Paula W Rushton, Delphine Labbé, Louise Demers, William C Miller, William B Mortenson, R Lee Kirby
Objective: In this study, we aimed to describe the burden of family caregivers providing powered wheelchair-related and overall assistance and test the hypotheses that caregiver burden correlates with participation, wheelchair skills capacity, anxiety, depression, and social support. Methods: Cross-sectional study. Participants included 35 family caregivers of powered wheelchair users. Caregivers were assessed using the Power Mobility Caregiver Assistive Technology Outcome Measure, Late Life Disability Instrument, Wheelchair Skills Test Questionnaire for caregivers, Hospital Anxiety and Depression Scale, and Interpersonal Support Evaluation List-12...
January 2017: Gerontology & Geriatric Medicine
https://www.readbyqxmd.com/read/28489656/consequences-of-traumatic-brain-injury-in-professional-american-football-players-a-systematic-review-of-the-literature
#12
Bodil C Vos, Karen Nieuwenhuijsen, Judith K Sluiter
OBJECTIVE: The purpose of this study was to systematically review the literature for the consequences Traumatic brain injury (TBI) has on cognitive, psychological, physical, and sports-related functioning in professional American Football players. DATA SOURCES: We performed a systematic search in 2 databases, PubMed and SPORTDiscus, to obtain literature from January 1990 to January 2015. To be eligible for inclusion, a study had to examine the relationship between TBI and the consequences for several aspects of functioning in professional American football players older than 18 years...
May 9, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28489293/the-role-of-family-history-of-depression-and-the-menopausal-transition-in-the-development-of-major-depression-in-midlife-women-study-of-women-s-health-across-the-nation-mental-health-study-swan-mhs
#13
Alicia Colvin, Gale A Richardson, Jill M Cyranowski, Ada Youk, Joyce T Bromberger
BACKGROUND: This study evaluated whether family history of depression predicts major depression in midlife women above and beyond static risk factors (such as personal history of depression prior to midlife) and risks that may change dynamically across midlife (such as menopausal, psychosocial, and health profiles). METHODS: Participants were 303 African American and Caucasian women (42-52 years at baseline) recruited into the Study of Women's Health across the Nation (SWAN) Mental Health Study (MHS) in Pittsburgh...
May 10, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28479153/longitudinal-cognitive-outcomes-of-clinical-phenotypes-of-late-life-depression
#14
Meghan Riddle, Guy G Potter, Douglas R McQuoid, David C Steffens, John L Beyer, Warren D Taylor
OBJECTIVE: Late-life depression is associated with cognitive deficits and increased risk for cognitive decline. The purpose of the study was to determine whether clinical characteristics could serve as phenotypes informative of subsequent cognitive decline. Age at depression onset and antidepressant remission at 3 months (acute response) and 12 months (chronic response) were examined. METHODS: In a longitudinal study of late-life depression in an academic center, 273 depressed and 164 never-depressed community-dwelling elders aged 60 years or older were followed on average for over 5 years...
March 28, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28475220/caring-for-a-centenarian-parent-an-exploratory-study-on-role-strains-and-psychological-distress
#15
Daniela Brandão, Oscar Ribeiro, Mónica Oliveira, Constança Paúl
OBJECTIVES: This study examined the main sources of strain and the presence of psychological distress in a sample of centenarians' children who assumed the role of primary caregivers. METHOD: A sample of 43 children (M age = 67.10 ± 6.67 years; 90.7% female) caring for a centenarian parent was interviewed and asked about their overall caregiving experience. Information on caregiving burden (Zarit Burden Interview) and psychological distress (Hospital Anxiety and Depression Scale) was also obtained...
May 5, 2017: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/28472702/depressive-subtypes-in-an-elderly-cohort-identified-using-latent-class-analysis
#16
E M Veltman, F Lamers, H C Comijs, M W M de Waal, M L Stek, R C van der Mast, D Rhebergen
BACKGROUND: Clinical findings indicate heterogeneity of depressive disorders, stressing the importance of subtyping depression for research and clinical care. Subtypes of the common late life depression are however seldom studied. Data-driven methods may help provide a more empirically-based classification of late-life depression. METHODS: Data were used from the Netherlands Study of Depression in Older People (NESDO) derived from 359 persons, aged 60 years or older, with a current diagnosis of major depressive disorder...
April 26, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28469817/no-relationship-between-baseline-salivary-alpha-amylase-and-state-trait-anxiety-inventory-score-in-drug-na%C3%A3-ve-patients-with-short-illness-duration-first-episode-major-depressive-disorder-an-exploratory-study
#17
Joanna Szarmach, Wiesław-Jerzy Cubała, Jerzy Landowski, Anna Chrzanowska
BACKGROUND: Salivary α-amylase (sAA) activity alternations are observed in major depressive disorder (MDD) being associated with depression severity and its specific psychopathological dimensions with anxiety being attributed to distress. No data is available on sAA in MDD according to Hamilton Rating Scale for Depression (HAMD-17) and State-Trait Anxiety Inventory (STAI). The exploratory study examines whether and to what extent baseline sAA level is interrelated to the psychopathological features including severity of symptoms and specific psychopathological dimensions...
April 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28462727/a-prospective-evaluation-of-the-depression-nutrient-intake-reverse-causality-hypothesis-in-a-cohort-of-community-dwelling-older-canadians
#18
Laura Gougeon, Hélène Payette, José A Morais, Pierrette Gaudreau, Bryna Shatenstein, Katherine Gray-Donald
Studies have investigated the potential protective effects that diet may have on late-life depression incidence. This disorder can, however, affect the person's food intake, widely known as the reverse causality hypothesis of depression. To test this hypothesis, we compared mean nutrient intakes from three 24-h recalls during the year depression was detected (Geriatric Depression Scale ≥11 or antidepressant medication) with intakes from 1 year earlier among community-dwelling older adults (67-83 years) followed up annually in the 4-year Québec Longitudinal Study on Nutrition and Aging, who were free of depression and cognitive impairment at baseline...
May 2, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28457805/negative-affectivity-aging-and-depression-results-from-the-neurobiology-of-late-life-depression-nbold-study
#19
David C Steffens, Lihong Wang, Kevin J Manning, Godfrey D Pearlson
OBJECTIVE: Neuroticism is a common yet understudied condition in older adults. We hypothesized that presence of high negativity affectivity (NA), a key feature of neuroticism, would be associated with different prefrontal cortex (PFC) activity and connectivity patterns in depressed and never-depressed older adults. METHODS: This is a baseline cross-sectional analysis of a cohort study of 52 depressed and 36 never-depressed older adults. Assessments included NA scores from the Type D Scale-14 and Montgomery-Åsberg Depression Rating Scale scores...
April 3, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28453490/plasma-amyloid-%C3%AE-and-alzheimer-s-disease-related-changes-in-late-life-depression
#20
Chiemi Yamazaki, Toshio Tamaoki, Akihiko Nunomura, Kenichi Tamai, Kazuyuki Yasuda, Nobutaka Motohashi
To elucidate an involvement of amyloid dysmetabolism in the pathophysiology of depression, we investigated associations of plasma amyloid-β (Aβ) levels with Alzheimer's disease-related changes in neuroimaging and cognitive dysfunction in patients with late-life depression. Higher plasma Aβ40, but not Aβ42 nor Aβ40/Aβ42 ratio, was associated with higher degree of parahippocampal atrophy and lower verbal fluency performance. Indeed, high plasma Aβ40 predicted poor cognitive prognosis of depressed patients with mild cognitive impairment...
2017: Journal of Alzheimer's Disease: JAD
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