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Late life depression

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https://www.readbyqxmd.com/read/27911019/the-impact-and-measurement-of-social-dysfunction-in-late-life-depression-an-evaluation-of-current-methods-with-a-focus-on-wearable-technology
#1
REVIEW
Sophie Hodgetts, Peter Gallagher, Daniel Stow, I Nicol Ferrier, John T O'Brien
OBJECTIVE: Depression is known to negatively impact social functioning, with patients commonly reporting difficulties maintaining social relationships. Moreover, a large body of evidence suggests poor social functioning is not only present in depression but that social functioning is an important factor in illness course and outcome. In addition, good social relationships can play a protective role against the onset of depressive symptoms, particularly in late-life depression. However, the majority of research in this area has employed self-report measures of social function...
December 2, 2016: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27890036/treatment-preferences-for-depression-in-the-elderly
#2
Claudia Luck-Sikorski, Janine Stein, Katharina Heilmann, Wolfgang Maier, Hanna Kaduszkiewicz, Martin Scherer, Siegfried Weyerer, Jochen Werle, Birgitt Wiese, Lilia Moor, Jens-Oliver Bock, Hans-Helmut König, Steffi G Riedel-Heller
BACKGROUND: If patients are treated according to their personal preferences, depression treatment success is higher. It is not known which treatment options for late-life depression are preferred by patients aged 75 years and over and whether there are determinants of these preferences. METHODS: The data were derived from the German "Late-life depression in primary care: needs, health care utilization, and costs (AgeMooDe)" study. Patients aged 75+ years (N = 1,230) were recruited from primary care practices...
November 28, 2016: International Psychogeriatrics
https://www.readbyqxmd.com/read/27889051/the-trajectory-of-negative-mood-and-depressive-symptoms-over-two-decades
#3
Katherine E Campbell, Lorraine Dennerstein, Mark Tacey, Cassandra E Szoeke
OBJECTIVE: Research aimed at understanding the temporal characteristics of depressive symptoms and negative mood in an older female population is lacking, despite the relationship between the two factors being well established. The aim of this study was to examine the characteristics of negative mood scores and depressive symptom scores in a longitudinal sample of women transitioning from mid-life to late life. STUDY DESIGN: This study was a longitudinal assessment of variables drawn from an epidemiological prospective study of women's healthy ageing...
January 2017: Maturitas
https://www.readbyqxmd.com/read/27870302/the-effect-on-mental-health-of-retiring-during-the-economic-crisis
#4
Michele Belloni, Elena Meschi, Giacomo Pasini
This paper investigates the causal impact of retirement on late-life mental health, a growing concern for public health, because major depressive disorders are the second leading cause of disability. We shed light on the role of economic conditions in shaping the effect of retirement on mental health by exploiting time and regional variation in the severity of the economic crisis across 10 European countries during 2004-2013. We use data from four waves of the Survey of Health, Ageing and Retirement in Europe and address the potential endogeneity of the retirement decision to mental health by applying a fixed-effects instrumental variables approach...
November 2016: Health Economics
https://www.readbyqxmd.com/read/27869986/physical-exercise-for-late-life-depression-customizing-an-intervention-for-primary-care
#5
Stamatula Zanetidou, Martino Belvederi Murri, Marco Menchetti, Giulio Toni, Fabrizio Asioli, Luigi Bagnoli, Donato Zocchi, Matteo Siena, Barbara Assirelli, Claudia Luciano, Mattia Masotti, Carlo Spezia, Monica Magagnoli, Mirco Neri, Mario Amore, Klea D Bertakis
OBJECTIVES: To identify which individual- and context-related factors influence the translation into clinical practice of interventions based on physical exercise (PE) as an adjunct to antidepressants (AD) for the treatment of late-life major depression (LLMD). DESIGN: Secondary analysis of a randomized controlled trial. SETTING: Primary care with psychiatric consultation-liaison programs (PCLPs)-organizational protocols that regulate the clinical management of individuals with psychiatric disorders...
November 21, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27866046/changes-in-depression-among-older-adults-in-china-a-latent-transition-analysis
#6
Yuhan Ni, Jenn-Yun Tein, Minqiang Zhang, Yawei Yang, Guoting Wu
BACKGROUND: Depression in late life is an important public health problem in developing countries. It is timely to investigate stability and transition patterns of depressive symptom subtypes. METHODS: Longitudinal data were used from the China Health and Retirement Longitudinal Study (CHARLS). A total of 853 women and 930 men aged 60-96 years were recruited. Latent class and latent transition analysis (LCA/LTA) were used to identify meaningful subgroups, transitions between those classes across time, and baseline demographic features that help to predict and design tailored interventions...
November 15, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27862293/a-meta-analysis-of-third-wave-mindfulness-based-cognitive-behavioral-therapies-for-older-people
#7
Naoko Kishita, Yuko Takei, Ian Stewart
OBJECTIVES: The aim of this study is to review the effectiveness of third wave mindfulness-based cognitive behavioral therapies (CBTs) for depressive or anxiety symptomatology in older adults across a wide range of physical and psychological conditions. METHODS: Electronic literature databases were searched for articles, and random-effects meta-analysis was conducted. RESULTS: Ten studies met the inclusion criteria, of which nine reported the efficacy of interventions on depressive symptoms and seven on anxiety symptoms...
November 11, 2016: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27856124/enhanced-molecular-aging-in-late-life-depression-the-senescent-associated-secretory-phenotype
#8
Breno Satler Diniz, Charles F Reynolds, Etienne Sibille, Chien-Wei Lin, George Tseng, Francis Lotrich, Howard J Aizenstein, Meryl A Butters
OBJECTIVE: This study aims to investigate whether a systemic molecular pattern associated with aging (senescent-associated secretory phenotype [SASP]) is elevated in adults with late-life depression (LLD), compared with never-depressed elderly comparison participants. DESIGN: Cross-sectional study. PARTICIPANTS: We included 111 older adults (80 with LLD and 31 comparison participants) in this study. MEASUREMENT: A panel of 22 SASP-related proteins was extracted from a previous multiplex protein panel performed in these participants...
August 31, 2016: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27834162/longitudinal-associations-between-late-life-depression-dimensions-and-cognitive-functioning-a-cross-domain-latent-growth-curve-analysis
#9
A Brailean, M J Aartsen, G Muniz-Terrera, M Prince, A M Prina, H C Comijs, M Huisman, A Beekman
BACKGROUND: Cognitive impairment and depression often co-occur in older adults, but it is not clear whether depression is a risk factor for cognitive decline, a psychological reaction to cognitive decline, or whether changes in depressive symptoms correlate with changes in cognitive performance over time. The co-morbid manifestation of depression and cognitive impairment may reflect either a causal effect or a common cause, depending on the specific symptoms experienced and the cognitive functions affected...
November 11, 2016: Psychological Medicine
https://www.readbyqxmd.com/read/27833238/screening-for-depression-among-community-dwelling-elders-usefulness-of-the-center-for-epidemiologic-studies-depression-scale
#10
Sebind Kumar, Anisha Nakulan, Sumesh Purushothaman Thoppil, Rejani Parameshwaran Parassery, Shaji Sivaraman Kunnukattil
CONTEXT: Though common, depressive disorders often remain undetected in late life. AIM: To examine the usefulness of Center for Epidemiologic Studies Depression (CES-D) for identifying depression among older people. SETTINGS AND DESIGN: Community resident older people (aged 65 years or more), were evaluated by clinicians trained in psychiatry, as part of a cross-sectional study of late-life depression. Assessments were done in the community...
September 2016: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/27827534/correlates-of-sleep-disturbances-in-depressed-older-persons-the-netherlands-study-of-depression-in-older-persons-nesdo
#11
Rian Johanna Gerdina Peters van Neijenhof, Erik van Duijn, Hannie C Comijs, Julia F van den Berg, Margot W M de Waal, Richard C Oude Voshaar, Roos C van der Mast
OBJECTIVES: Sleep disturbances are common among depressed older persons. To gain insight into sleep disturbances in late-life depression, their occurrence and correlates were assessed. METHODS: Baseline data of 294 depressed older persons of the Netherlands Study of Depression in Older persons study were used. A diagnosis of current depression according to the diagnostic and statistical manual of mental disorders-IV (DSM-IV) was assessed with the Composite International Diagnostic Interview...
November 9, 2016: Aging & Mental Health
https://www.readbyqxmd.com/read/27825555/neuroticism-traits-selectively-impact-long-term-illness-course-and-cognitive-decline-in-late-life-depression
#12
Kevin J Manning, Grace Chan, David C Steffens
OBJECTIVES: Neuroticism is a broad construct that conveys a predisposition to experience psychological distress and negative mood states. Vulnerability to stress (VS) is one neuroticism trait that has been linked to worse mood and cognitive outcomes in older adults. We hypothesized that elevated VS would be associated with worse illness course and cognitive decline in older adults with late-life major depression (LLD). DESIGN: Participants were enrolled in the Neurocognitive Outcomes of Depression in the Elderly (NCODE), a longitudinal investigation of the predictors of poor illness course and cognitive decline in LLD...
October 13, 2016: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27811155/olfaction-is-related-to-motor-function-in-older-adults
#13
Qu Tian, Susan M Resnick, Stephanie A Studenski
BACKGROUND: Among older adults, both olfaction and motor function predict future cognitive decline and dementia, suggesting potential shared causal pathways. However, it is not known whether olfactory and motor function are independently related in late life. METHODS: We assessed cross-sectional associations of olfaction with motor and cognitive function, using concurrent data on olfactory function, mobility, balance, fine motor function, manual dexterity, and cognition in 163 Baltimore Longitudinal Study of Aging participants aged 60 and older without common neurological diseases (n = 114 with available cognitive data)...
November 3, 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/27810721/social-stratification-of-general-psychopathology-trajectories-and-young-adult-social-outcomes-a-second-order-growth-mixture-analysis-over-the-early-life-course
#14
Tae Kyoung Lee, Kandauda A S Wickrama, Catherine Walker O'Neal, Frederick O Lorenz
BACKGROUND: Research has documented heterogeneous developmental trajectories of specific symptoms, such as anxiety and depression, in late childhood and adolescence. Few studies, however, have examined the heterogeneity of general psychopathology (GPP) trajectories considering symptoms of anxiety, depression, and hostility in adolescence simultaneously. Identifying antecedents for distinct trajectory groups of GPP, and their respective consequences, may provide insight into the etiological underpinnings of social antecedents of different symptoms and inform the targets and timing of intervention...
October 13, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27810716/risk-factors-for-late-life-depression-and-correlates-of-antidepressant-use-in-costa-rica-results-from-a-nationally-representative-longitudinal-survey-of-older-adults
#15
Alex K Gertner, Marisa Elena Domino, William H Dow
BACKGROUND: Risk factors for late-life depression have been studied in high-income countries, but there have been no longitudinal studies from middle-income countries. This study reports risk factors for late-life depression and correlates of antidepressant using the Costa Rican Longevity and Healthy Aging Study (CRELES), a nationally representative cohort of adults age 60 and over. METHODS: CRELES contains baseline interviews in 2005 (n=2827) with follow-up interviews in 2007 and 2009...
October 11, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27806704/vascular-depression-consensus-report-a-critical-update
#16
EDITORIAL
Howard J Aizenstein, Andrius Baskys, Maura Boldrini, Meryl A Butters, Breno S Diniz, Manoj Kumar Jaiswal, Kurt A Jellinger, Lev S Kruglov, Ivan A Meshandin, Milija D Mijajlovic, Guenter Niklewski, Sarah Pospos, Keerthy Raju, Kneginja Richter, David C Steffens, Warren D Taylor, Oren Tene
BACKGROUND: Vascular depression is regarded as a subtype of late-life depression characterized by a distinct clinical presentation and an association with cerebrovascular damage. Although the term is commonly used in research settings, widely accepted diagnostic criteria are lacking and vascular depression is absent from formal psychiatric manuals such as the Diagnostic and Statistical Manual of Mental Disorders, 5(th) edition - a fact that limits its use in clinical settings. Magnetic resonance imaging (MRI) techniques, showing a variety of cerebrovascular lesions, including extensive white matter hyperintensities, subcortical microvascular lesions, lacunes, and microinfarcts, in patients with late life depression, led to the introduction of the term "MRI-defined vascular depression"...
November 3, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27801933/timing-of-physical-activity-apolipoprotein-e-%C3%AE%C2%B54-genotype-and-risk-of-incident-mild-cognitive-impairment
#17
Janina Krell-Roesch, Anna Pink, Rosebud O Roberts, Gorazd B Stokin, Michelle M Mielke, Kathleen A Spangehl, Mairead M Bartley, David S Knopman, Teresa J H Christianson, Ronald C Petersen, Yonas E Geda
OBJECTIVES: To investigate the timing (mid- vs late life) of physical activity, apolipoprotein (APO)E ε4, and risk of incident mild cognitive impairment (MCI). DESIGN: Prospective cohort study. SETTING: Mayo Clinic Study of Aging (Olmsted County, MN). PARTICIPANTS: Cognitively normal elderly adults (N = 1,830, median age 78, 50.2% female). MEASUREMENTS: Light, moderate, and vigorous physical activities in mid- and late life were assessed using a validated questionnaire...
November 1, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27790137/association-of-cerebral-amyloidosis-blood-pressure-and-neuronal-injury-with-late-life-onset-depression
#18
Min Soo Byun, Young Min Choe, Bo Kyung Sohn, Dahyun Yi, Ji Young Han, Jinsick Park, Hyo Jung Choi, Hyewon Baek, Jun Ho Lee, Hyun Jung Kim, Yu Kyeong Kim, Eun Jin Yoon, Chul-Ho Sohn, Jong Inn Woo, Dong Young Lee
Previous literature suggests that Alzheimer's disease (AD) process may contribute to late-life onset depression (LLOD). Therefore, we investigated the association of LLOD with cerebral amyloidosis and neuronal injury, the two key brain changes in AD, along with vascular risks. Twenty nine non-demented individuals who first experienced major depressive disorder (MDD) after age of 60 years were included as LLOD subjects, and 27 non-demented elderly individuals without lifetime experience of MDD were included as normal controls (NC)...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/27780491/association-of-adverse-childhood-experiences-with-lifetime-mental-and-substance-use-disorders-among-men-and-women-aged-50-years
#19
Namkee G Choi, Diana M DiNitto, C Nathan Marti, Bryan Y Choi
BACKGROUND: Given growing numbers of older adults with mental and substance use disorders (MSUDs), this study examined the association between ten types of adverse childhood experiences (ACEs) and lifetime MSUDs among those aged 50+. METHODS: Data (N = 14,738 for the 50+ age group) came from the 2012 to 2013 National Epidemiologic Survey on Alcohol and Related Conditions. Using multivariable binary logistic regression analyses, we examined relationships between ten ACEs and six lifetime MSUDs (major depressive disorder (MDD) and anxiety, post-traumatic stress, alcohol use, drug use, and nicotine use disorders)...
October 26, 2016: International Psychogeriatrics
https://www.readbyqxmd.com/read/27779764/quality-of-life-anxiety-and-depression-symptoms-in-early-and-late-pregnancy-in-women-with-pregestational-diabetes
#20
Nicoline C Do, Anna L Secher, Per Cramon, Lene Ringholm, Torquil Watt, Peter Damm, Elisabeth R Mathiesen
INTRODUCTION: To explore changes in health-related quality of life, anxiety and depression symptoms during pregnancy in women with pregestational diabetes. MATERIAL AND METHODS: An observational cohort study including 137 pregnant women with pregestational diabetes (110 with type 1 and 27 with type 2). To evaluate changes from early to late pregnancy, the internationally validated questionnaires 36-Item Short-Form Health Survey (SF-36) and Hospital Anxiety and Depression Scale (HADS) were completed at 8 and 33 gestational weeks...
October 25, 2016: Acta Obstetricia et Gynecologica Scandinavica
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