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Late life depression

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https://www.readbyqxmd.com/read/29327630/the-specter-of-the-primitive
#1
Gregory S Rizzolo
Traditional psychoanalytic theories of development hold that the adult neurotic can regress, or has already regressed, to the childhood arrests and/or fixations in which his pathology originated. More recent critiques have called this possibility into question. It is unlikely that anyone can roll back the additions and modifications of lifespan development in a full-fledged return to the needs, wishes, and anxieties of childhood. By regression, though, some analysts mean not a full-fledged return to an earlier developmental phase, but a non-phase-specific slip into primitive fantasies and defenses...
December 2017: Journal of the American Psychoanalytic Association
https://www.readbyqxmd.com/read/29322164/efficacy-of-transdermal-estradiol-and-micronized-progesterone-in-the-prevention-of-depressive-symptoms-in-the-menopause-transition-a-randomized-clinical-trial
#2
Jennifer L Gordon, David R Rubinow, Tory A Eisenlohr-Moul, Kai Xia, Peter J Schmidt, Susan S Girdler
Importance: The menopause transition and early postmenopausal period are associated with a 2- to 4-fold increased risk for clinically significant depressive symptoms. Although a few studies suggest that hormone therapy can effectively manage existing depression during this time, to our knowledge, there have been no studies testing whether hormone therapy can prevent the onset of perimenopausal and early postmenopausal depressive symptoms. Objective: To examine the efficacy of transdermal estradiol plus intermittent micronized progesterone (TE+IMP) in preventing depressive symptom onset among initially euthymic perimenopausal and early postmenopausal women...
January 10, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29318648/childhood-abuse-and-late-life-depression-mediating-effects-of-psychosocial-factors-for-early-and-late-onset-depression
#3
Ilse Wielaard, Mathijs Hoyer, Didi Rhebergen, Max L Stek, Hannie C Comijs
No abstract text is available yet for this article.
January 10, 2018: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29305239/can-repetitive-transcranial-magnetic-stimulation-enhance-cognitive-control-in-late-life-depression
#4
EDITORIAL
Daniel M Blumberger
No abstract text is available yet for this article.
December 6, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29295706/a-qualitative-study-on-older-primary-care-patients-perspectives-on-depression-and-its-treatments-potential-barriers-to-and-opportunities-for-managing-depression
#5
Anne Stark, Hanna Kaduszkiewicz, Janine Stein, Wolfgang Maier, Kathrin Heser, Siegfried Weyerer, Jochen Werle, Birgitt Wiese, Silke Mamone, Hans-Helmut König, Jens-Oliver Bock, Steffi G Riedel-Heller, Martin Scherer
BACKGROUND: Depression is one of the most common mental disorders in old age and is associated with various negative health consequences for the affected individual. Studies suggest that patients' views on depression have an impact on help-seeking behaviour and treatment. It is thus important to investigate the patient's perspective in order to ascertain optimum management of depression in late life. However, studies on depression and its treatment exploring the perspectives of primary care patients 75 years or older, are rare...
January 3, 2018: BMC Family Practice
https://www.readbyqxmd.com/read/29280040/the-relationships-between-timing-of-first-childbirth-parity-and-health-related-quality-of-life
#6
Sangshin Park, Nam-Kyong Choi
PURPOSE: A few studies have investigated the relationship between age at first childbirth and health-related quality of life (HRQoL). This study examined the relationship between age at first childbirth and HRQoL and whether parity mediates this timing of the first childbirth-HRQoL relationship in women aged 50 years or above. METHODS: The study population included 5146 parous women ≥ 50 years in the cross-sectional survey, the Korea National Health and Nutrition Examination Survey 2010-2012...
December 26, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/29279022/personality-and-its-relationship-to-depression-and-cognition-in-older-adults-implications-for-practice
#7
Nasreen A Sadeq, Victor Molinari
OBJECTIVES: Personality is an important contributor to an individual's mental health and is consistently linked to the two most prevalent mental health conditions among older adults: dementia and depression. This review summarizes the current findings on personality and its association with cognitive decline and depression, as well as treatment outcomes and possible intervention strategies. METHODS: Literature searches were conducted in Web of Science, PubMed, and PsycINFO...
December 8, 2017: Clinical Gerontologist
https://www.readbyqxmd.com/read/29249958/unlocking-neurocognitive-substrates-of-late-life-affective-symptoms-using-the-research-domain-criteria-worry-is-an-essential-dimension
#8
Sherry A Beaudreau, Nathan C Hantke, Nehjla Mashal, Christine E Gould, Victor W Henderson, Ruth O'Hara
While investigations have sought to identify the distinct and shared contributions of anxiety and depression to neurocognitive processes in late life, less is known regarding the further contribution of worry, a unique and critical dimension of affective dysregulation. Capturing the full range of symptoms, as inspired by the NIH Research Domain Criteria (RDoC), may provide finer-grained information on inter-relationships among worry, anxiety and depression on neurocognitive processing in later life. The objective of this study was to determine if the dimensional trait of worry intensifies known negative associations of dimensional measures of anxiety and depressive symptoms with neurocognitive processes, specifically cognitive control and memory processes...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29235659/effect-of-metabolic-syndrome-on-late-life-depression-associations-with-disease-severity-and-treatment-resistance
#9
John S Mulvahill, Ginger E Nicol, David Dixon, Eric J Lenze, Jordan F Karp, Charles F Reynolds, Daniel M Blumberger, Benoit H Mulsant
BACKGROUND/OBJECTIVES: Metabolic syndrome (MetS) is the co-occurrence of obesity and metabolic derangements. Prior research implicates MetS in prolongation of the course of depression in older adults, but its effect on antidepressant response is unknown in this population. The objective was to determine whether MetS and related metabolic dyscrasias are associated with decreased rate of remission from depression in older adults treated pharmacologically for depression. DESIGN: Secondary analysis of a randomized controlled trial...
December 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29231914/determinants-of-late-life-depression-in-residents-of-long-term-care-facility
#10
Urszula Horwath, Katarzyna Szczerbińska
Mental disorders, such as dementia and depression, are beside chronic somatic diseases, the most common problem in residents of longterm care facilities (LTCF). Late-life depression refers to depressive symptoms that arise in adults older than 65 years. According to literature review, older people tend to differ from middle-aged adults in presentation of depression. AIM: Mental disorders, such as dementia and depression, are beside chronic somatic diseases, the most common problem in residents of longterm care facilities (LTCF)...
November 23, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29227034/the-clinical-course-of-late-life-bipolar-disorder-looking-back-and-forward
#11
Annemiek Dols, Nicole Korten, Hannie Comijs, Sigfried Schouws, Moniek van Dijk, Ursula Klumpers, Aartjan Beekman, Ralph Kupka, Max Stek
OBJECTIVES: Little is known about the course of late-life bipolar disorder (LLBD). First, we studied patients with LLBD retrospectively with regard to age at first mood episode, onset polarity, predominant polarity and episode density and its associations with other clinical variables. Next, we examined prospectively the clinical course and its associated factors. METHODS: Data were used from a dynamic cohort (Dutch Older Bipolars [DOBi]) including 101 patients with LLBD (mean age of 68...
December 11, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29222609/evaluating-cognition-in-individuals-with-huntington-disease-neuro-qol-cognitive-functioning-measures
#12
Jin-Shei Lai, Siera Goodnight, Nancy R Downing, Rebecca E Ready, Jane S Paulsen, Anna L Kratz, Julie C Stout, Michael K McCormack, David Cella, Christopher Ross, Jenna Russell, Noelle E Carlozzi
PURPOSE: Cognitive functioning impacts health-related quality of life (HRQOL) for individuals with Huntington disease (HD). The Neuro-QoL includes two patient-reported outcome (PRO) measures of cognition-Executive Function (EF) and General Concerns (GC). These measures have not previously been validated for use in HD. The purpose of this analysis is to evaluate the reliability and validity of the Neuro-QoL Cognitive Function measures for use in HD. METHODS: Five hundred ten individuals with prodromal or manifest HD completed the Neuro-QoL Cognition measures, two other PRO measures of HRQOL (WHODAS 2...
December 8, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/29207962/a-partially-supervised-physical-activity-program-for-adult-and-adolescent-survivors-of-childhood-cancer-surfit-study-design-of-a-randomized-controlled-trial-nct02730767
#13
Corina S Rueegg, Susi Kriemler, Simeon J Zuercher, Christina Schindera, Andrea Renner, Helge Hebestreit, Christian Meier, Prisca Eser, Nicolas X von der Weid
BACKGROUND: Beyond survival of nowadays >80%, modern childhood cancer treatment strives to preserve long-term health and quality of life. However, the majority of today's survivors suffer from short- and long-term adverse effects such as cardiovascular and pulmonary diseases, obesity, osteoporosis, fatigue, depression, and reduced physical fitness and quality of life. Regular exercise can play a major role to mitigate or prevent such late-effects. Despite this, there are no data on the effects of regular exercise in childhood cancer survivors from randomized controlled trials (RCTs)...
December 5, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29202654/sensation-and-psychiatry-linking-age-related-hearing-loss-to-late-life-depression-and-cognitive-decline
#14
Bret R Rutherford, Katharine Brewster, Justin S Golub, Ana H Kim, Steven P Roose
Recent research has linked age-related hearing loss to impaired performance across cognitive domains and increased risk for dementia diagnosis. The data linking hearing impairment to incident late-life depression are more mixed but suggest that diminished hearing does increase risk for depression. Behavioral mechanisms may explain these associations, such as the withdrawal of older adults from situations in which they may have difficulty hearing and communicating, which may contribute to the development of social isolation, loneliness, and consequent cognitive decline and depression...
December 5, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29198213/presence-of-neuroticism-and-antidepressant-remission-rates-in-late-life-depression-results-from-the-neurobiology-of-late-life-depression-nbold-study
#15
David C Steffens, Rong Wu, James J Grady, Kevin J Manning
Neuroticism in older adults is common yet understudied, particularly its effects on depression treatment outcomes. We hypothesized that presence of high neuroticism would be associated with lower 12-week remission rates in older depressed sertraline-treated patients. In this longitudinal cohort study, 43 depressed older adults completed the Revised NEO Personality Inventory (NEO PI-R). A study psychiatrist administered the Montgomery Ǻsberg Depression Rating Scale (MADRS), and the Cumulative Illness Rating Scale (CIRS, a measure of medical burden) at baseline, and the MADRS at each clinical visit...
December 4, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/29195804/-psychostimulants-for-late-life-depression
#16
P Delsalle, J-P Schuster, A von Gunten, F Limosin
OBJECTIVES: The use of psychostimulants in the treatment of depressive disorders is receiving renewed interest. Recent publications suggest a particular interest of psychostimulants in the treatment of depression in the elderly. The aim of this article is to review the literature on the role of psychostimulants in the treatment of depression in older adults. METHODS: The literature review focused on efficacy and tolerability studies of psychostimulants in the treatment of depression for the elderly that were published between 1980 and 2016...
November 28, 2017: L'Encéphale
https://www.readbyqxmd.com/read/29193360/patterns-of-late-life-depressive-symptoms-and-subsequent-declines-in-cognitive-domains
#17
J Cai Gillis, Shun-Chiao Chang, Elizabeth E Devore, Bernard A Rosner, Francine Grodstein, Olivia I Okereke
BACKGROUND: Depression frequently co-occurs with cognitive decline, but the nature of this association is unclear. We examined relations of late-life depressive symptom patterns to subsequent domain-specific cognitive changes. METHODS: Depressive symptoms were measured at up to 3 timepoints among 11,675 Nurses' Health Study participants prior to cognitive testing. Depressive symptom patterns were categorized as non-depressed, variable or persistent, based on published severity cutpoints...
December 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29180946/educational-inequalities-in-late-life-depression-across-europe-results-from-the-generations-and-gender-survey
#18
Thomas Hansen, Britt Slagsvold, Marijke Veenstra
This study explores country- and gender-stratified educational differences in depression among older adults from 10 European countries. We examine inequalities in both absolute (prevalence differences) and relative (odds ratios) terms and in bivariate and multivariate models. We use cross-sectional, nationally representative data from the generations and gender survey. The analysis comprises 27,331 Europeans aged 60-80. Depression is measured with a seven-item version of the Center for Epidemiologic Studies Depression scale...
December 2017: European Journal of Ageing
https://www.readbyqxmd.com/read/29172763/depression-work-and-family-roles-and-the-gendered-life-course
#19
Katrina Leupp
Despite the importance of employment for shaping mental health over the life course, little is known about how the mental health benefits of employment change as individuals age through their prime employment and child-rearing years. This study examines the National Longitudinal Survey of Youth, 1979 Cohort ( N = 8,931), following respondents from their late 20s to mid-50s. Results suggest that among women, the aging of children is especially salient for shaping the mental health consequences of employment...
December 2017: Journal of Health and Social Behavior
https://www.readbyqxmd.com/read/29170758/design-and-rationale-for-a-technology-based-healthy-lifestyle-intervention-in-older-adults-grieving-the-loss-of-a-spouse
#20
Sarah T Stahl, James Emanuel, Steven M Albert, Mary Amanda Dew, Richard Schulz, Gregg Robbins-Welty, Charles F Reynolds
Introduction: Experiencing the death of a spouse during late life is associated with an increased risk of developing debilitating mental health problems. Healthy lifestyle practices, such as regular exercise, healthy eating, and good sleep hygiene are promising strategies to influence the mental health and associated physical symptoms of late-life spousal bereavement. Objective: This paper describes the design and rationale of an intervention development study addressing selective and indicated prevention of depression, anxiety, and/or complicated grief disorder(s) among adults 60 years and older who are grieving the recent loss (within 8 months) of a spouse or partner...
December 2017: Contemporary Clinical Trials Communications
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