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https://www.readbyqxmd.com/read/29754154/-series-caries-prevention-in-historical-perspective-fluoride
#1
H Kalsbeek
Shortly after the Second World War it became known in the Netherlands that fluoride can contribute to the prevention of dental caries. As to how this effect was achieved, opinions differed. Initially, the dominant the view was that fluoride had to be absorbed into the enamel and dentine during tooth formation to make the teeth resistant to caries. Later it was discovered that decalcification of the enamel is inhibited if fluoride is present in the dental plaque. While in the beginning water fluoridation was considered to be the most effective measure to prevent caries, the current position is that tooth brushing with fluoride toothpaste plays the most important role in caries prevention...
May 2018: Nederlands Tijdschrift Voor Tandheelkunde
https://www.readbyqxmd.com/read/29737333/multimodal-imaging-of-undecalcified-tissue-sections-by-maldi-ms-and-%C3%AE-xrf
#2
Anastasiya Svirkova, Anna Turyanskaya, Lukas Perneczky, Christina Streli, Martina Marchetti-Deschmann
Matrix-assisted laser desorption/ionisation mass spectrometric imaging (MALDI MSI) is a technique that provides localized information on intact molecules in a sample. Micro X-ray fluorescence (μXRF) imaging allows the examination of the spatial distribution of elements in a sample without any morphological changes. These methods have already been applied separately to different tissues, organs, plants and bacterial films, but, to the best of our knowledge, they have yet to be coupled in a multimodal analysis...
May 8, 2018: Analyst
https://www.readbyqxmd.com/read/29715705/randomized-co-mparison-of-tri-fecta-and-p-erimount-magna-ease-supraannular-aortic-xenografts-co-tri-p-study
#3
Arnaud Van Linden, Mani Arsalan, Thore Körschgen, Johannes Blumenstein, Jörg Kempfert, Florian Hecker, Thomas Walther
BACKGROUND:  Modern supraannular aortic xenografts offer a special design, thus providing maximized opening area for improved hemodynamics. The aim of this study was a prospectively randomized comparison of the Trifecta and the Perimount Magna Ease valves based on metric annulus sizing. METHODS:  A total of 100 patients with aortic stenosis undergoing aortic valve replacement (AVR) with or without concomitant procedures were prospectively included. After decalcification of the annulus, stratified intraoperative randomization was performed...
May 1, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29702250/type-2-diabetes-impairs-angiogenesis-and-osteogenesis-in-calvarial-defects-microct-study-in-zdf-rats
#4
Guavri Caliaperoumal, Maite Souyet, Morad Bensidhoum, Herve Petite, Fani Anagnostou
OBJECTIVES: The present study was motivated by the fact that bone regeneration in the compromised vascular microenvironment of T2DM is challenging and the factors that determine the adverse bone regeneration outcomes are poorly understood. For this purpose the effect of T2DM on osteogenic and angiogenic healing potential of calvarial bone, was evaluated in Zucker diabetic fatty (ZDF) rats, an established rat model for obese T2DM. MATERIALS AND METHODS: The study used 16-week-old ZDF rats and their age-matched controls, Zucker Lean (ZL)...
April 24, 2018: Bone
https://www.readbyqxmd.com/read/29697396/influence-of-tricalcium-silicate-on-course-of-traumatic-pulpitis
#5
I Kovach, K Buniatian, A Makarevych, A Verbyts'ka, V Gargin
The use of Tricalcium Silicate (TS) as an odontotropic preparation makes it possible to create a hermetic crown restoration with a high degree of adhesion. However, the use of TS silicate by direct pulp capping remains disputable. The aim of this study was to determine the effects of TS on course of traumatic pulpitis by detection of morpho-functional peculiarities of changes in pulp tissue. We performed experimental investigation (on rabbits, males, aging three-month) for study of the morpho-functional changes of the pulp tissues with modeling of traumatic pulpitis and direct pulp capping with TS preparation (8 animals, investigated group) and calcium hydroxide (Calasept, NORDISKA DENTAL) preparation (8 animals, comparison group)...
March 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29680163/decalcification-and-survival-of-benthic-foraminifera-under-the-combined-impacts-of-varying-ph-and-salinity
#6
Laurie M Charrieau, Helena L Filipsson, Yukiko Nagai, Sachiko Kawada, Karl Ljung, Emma Kritzberg, Takashi Toyofuku
Coastal areas display natural large environmental variability such as frequent changes in salinity, pH, and carbonate chemistry. Anthropogenic impacts - especially ocean acidification - increase this variability, which may affect the living conditions of coastal species, particularly, calcifiers. We performed culture experiments on living benthic foraminifera to study the combined effects of lowered pH and salinity on the calcification abilities and survival of the coastal, calcitic species Ammonia sp. and Elphidium crispum...
April 3, 2018: Marine Environmental Research
https://www.readbyqxmd.com/read/29661113/histology-vascularity-and-innervation-of-the-glenoid-labrum
#7
Abduelmenem Alashkham, Abdulrahman Alraddadi, Paul Felts, Roger Soames
BACKGROUND: Although the glenoid labrum has an important role in shoulder stability, little is known about its composition, vascularity and innervation. The aims of this study were therefore to evaluate the histology, vascularity and innervation of the glenoid labrum. MATERIALS AND METHODS: Ten glenoid labrum specimens (three male, two female: mean age 81.2 years, range 76-90 years) were detached at the glenoid neck. Following decalcification, sections were cut through the whole thickness of each specimen perpendicular to the glenoid labrum at 12 radii corresponding to a clock face superimposed on the glenoid fossa...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29658405/real-time-intracochlear-imaging-of-automated-cochlear-implant-insertions-in-whole-decalcified-cadaver-cochleas-using-ultrasound
#8
Thomas G Landry, Guy Earle, Jeremy A Brown, Manohar L Bance
OBJECTIVES: This study aimed to determine the feasibility of combining high-frequency ultrasound imaging, automated insertion, and force sensing to yield more information about cochlear implant insertion dynamics. METHODS: An apparatus was developed combining these aspects along with software to control implant and imaging probe positions. Decalcified unfixed human cochleas were implanted at various speeds, insertion sites, and implant models while imaging near the implant tip throughout insertion and recording force data from the cochlea mounting stage...
April 16, 2018: Cochlear Implants International
https://www.readbyqxmd.com/read/29630138/adhesives-for-fixed-orthodontic-brackets
#9
REVIEW
Nicky A Mandall, Joy Hickman, Tatiana V Macfarlane, Rye Cr Mattick, Declan T Millett, Helen V Worthington
BACKGROUND: Bonding of orthodontic brackets to teeth is important to enable effective and efficient treatment with fixed appliances. The problem is bracket failure during treatment which increases operator chairside time and lengthens treatment time. A prolonged treatment is likely to increase the oral health risks of orthodontic treatment with fixed appliances one of which is irreversible enamel decalcification. This is an update of the Cochrane Review first published in 2003. A new full search was conducted on 26 September 2017 but no new studies were identified...
April 9, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29603124/comparison-of-two-ancient-dna-extraction-protocols-for-skeletal-remains-from-tropical-environments
#10
Maria A Nieves-Colón, Andrew T Ozga, William J Pestle, Andrea Cucina, Vera Tiesler, Travis W Stanton, Anne C Stone
OBJECTIVES: The tropics harbor a large part of the world's biodiversity and have a long history of human habitation. However, paleogenomics research in these climates has been constrained so far by poor ancient DNA yields. Here we compare the performance of two DNA extraction methods on ancient samples of teeth and petrous portions excavated from tropical and semi-tropical sites in Tanzania, Mexico, and Puerto Rico (N = 12). MATERIALS AND METHODS: All samples were extracted twice, built into double-stranded sequencing libraries, and shotgun sequenced on the Illumina HiSeq 2500...
March 30, 2018: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/29600734/inhalation-therapy-for-repairing-damaged-elastin-fibers-and-decelerating-elastinolysis-in-chronic-obstructive-pulmonary-disease
#11
Rob Janssen, Ianthe Piscaer, Emiel Fm Wouters
Current pharmacologic therapy of chronic obstructive pulmonary disease (COPD) can reduce respiratory symptoms and exacerbation frequency. However, no single COPD intervention except for lung transplantation has proven effective in recovering lung function. Lung elasticity is reduced in COPD lungs, which is for a large part due to chronically enhanced elastin degradation. Elastin calcification and formation of advanced glycation end products (AGEs) may also contribute to this. Areas covered: We propose inhalation therapy to induce repair of damaged pulmonary elastin fibers by stimulating tropoelastin synthesis, assembly and crosslinking in order to improve lung function in patients with COPD...
May 2018: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/29587160/extending-neutron-autoradiography-technique-for-boron-concentration-measurements-in-hard-tissues
#12
Lucas Provenzano, María Silvina Olivera, Gisela Saint Martin, Luis Miguel Rodríguez, Daniel Fregenal, Silvia I Thorp, Emiliano C C Pozzi, Paula Curotto, Ian Postuma, Saverio Altieri, Sara J González, Silva Bortolussi, Agustina Portu
The neutron autoradiography technique using polycarbonate nuclear track detectors (NTD) has been extended to quantify the boron concentration in hard tissues, an application of special interest in Boron Neutron Capture Therapy (BNCT). Chemical and mechanical processing methods to prepare thin tissue sections as required by this technique have been explored. Four different decalcification methods governed by slow and fast kinetics were tested in boron-loaded bones. Due to the significant loss of the boron content, this technique was discarded...
March 14, 2018: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/29506318/the-stapedial-artery-in-the-mongolian-gerbil-meriones-unguiculatus
#13
Jacek Kuchinka
The persistent stapedial artery is a component of the main arterial roads of the head in some animal groups (Frąckowiak: Roczn Akad Roln Poznań 336 (2003) 1-81). This type of vascularization occurs in the Mongolian gerbil, among others. The stapedial artery is common in a variety of forms in rodents. It has been described, for example, in Sciuridae, Muridae, Heteromyidae, Geomyidae, Splacidae, Cricetidae, Arvicolinae, and in genus Jaculus (Cox and Hautier: Evolution of the Rodents: Advances in phylogeny, Functional Morphology and Development, 2015)...
March 5, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29496436/myectomy-and-la-to-lv-conduit-for-severe-calcific-mitral-stenosis-and-hypertrophic-cardiomyopathy
#14
Zahara Meghji, Anita Nguyen, Jeffrey B Geske, Hartzell V Schaff
Severe calcific mitral valve stenosis can rarely occur concomitantly with obstructive hypertrophic cardiomyopathy. In these patients, surgical decalcification of the stenotic mitral valve followed by mitral valve replacement carries significant operative risk and may result in paravalvular leakage, atrioventricular groove disruption, and excessive bleeding. We report the first 2 cases of obstructive hypertrophic cardiomyopathy with severe calcific mitral valve stenosis successfully treated with concomitant transaortic septal myectomy and bypass of the stenotic mitral valve using a valved left atrium to left ventricular conduit...
February 26, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29495655/single-blind-randomized-clinical-trial-on-the-efficacy-of-an-interdental-cleaning-device-in-orthodontic-patients
#15
Alessandro Quaranta, Olivia Marchisio, Orlando D'Isidoro, Anna-Maria Genovesi, Ugo Covani
BACKGROUND: It is well known that poor oral hygiene during orthodontic treatment may lead to development of gingivitis, probing pocket depth, hyperplastic tissue, decalcification, dental caries and white spot lesions on the coronal surfaces of teeth. METHODS: 22 patients with the following inclusion criteria were enrolled in the present study: fixed orthodontic treatment , 12-18 years, systemically healthy , no history of periodontal treatment, periodontal health or gingivitis...
February 13, 2018: Minerva Stomatologica
https://www.readbyqxmd.com/read/29461224/-microecological-changes-in-the-intestine-and-its-effect-on-the-condition-of-hard-tissues-of-teeth-in-adolescence
#16
T Shishniashvili, T Suladze, M Makhviladze, M Pkhaladze
On the background of microecological changes in the gastrointestinal tract, mineral and protein metabolism is disrupted, biochemical changes occur in the phosphorus-calcium metabolism in the bones of the skeleton and hard tissues of the teeth. The aim of the research was to study the activity of the caries process, characterized by progressive decalcification, under conditions of microecological changes in the intestine and its effect on the processes of endogenous calcium assimilation in adolescence. Within the frames of the research 68 adolescents aged 11 to 17 years with various degrees of pathology of the gastrointestinal tract were examined...
January 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29434174/macrophages-highly-express-carbonic-anhydrase-2-and-play-a-significant-role-in-demineralization-of-the-ectopic-calcification
#17
Agian Jeffilano Barinda, Koji Ikeda, Ken-Ichi Hirata, Noriaki Emoto
Vascular calcification is an important risk factor for cardiovascular disease, and is closely associated with all-cause mortality. Recently, it has been revealed that vascular calcification is not a passive precipitation of circulating minerals, but is a process actively regulated through machinery similar to bone formation. During the bone remodeling, osteoclasts execute the bone resorption by releasing hydrogen ions to dissolve minerals; however, molecular mechanisms underlying decalcification of ectopically calcified lesions remain largely unknown...
October 16, 2017: Kobe Journal of Medical Sciences
https://www.readbyqxmd.com/read/29424622/alveolar-bone-remodeling-after-tooth-extraction-in-irradiated-mandible-an-experimental-study-with-canine-model
#18
Venni Heinonen, Timo J Ruotsalainen, Lauri Paavola, Jopi J Mikkonen, Pekka Asikainen, Arto P Koistinen, Arja M Kullaa
OBJECTIVES: The aim of the present study is to investigate the morphological and cellular changes in dental extraction socket that has been irradiated after the tooth extraction and to describe morphological characteristics of the osteocytes and osteocyte-lacunar-canalicular network (LCN) by scanning electron microscopy (SEM). MATERIAL AND METHODS: Five beagle dogs aged 1-2 years were used in this study. One side of each mandible was irradiated in two sessions and the other side of mandible (non-irradiated) served as a control...
March 2018: Ultrastructural Pathology
https://www.readbyqxmd.com/read/29403224/clinical-evaluation-of-bond-failures-and-survival-of-mandibular-canine-to-canine-bonded-retainers-during-a-12-year-time-span
#19
Marcello Maddalone, Elisa Rota, Luca Mirabelli, Pier M Venino, Gianluca Porcaro
Aim: The aim of this study was to assess the effectiveness of the 3-3 mandibular lingual stainless steel retainer to prevent a relapse of orthodontic treatment during the 12-year time span of the survey. Materials and methods: Fifty patients with canine-to-canine bonded retainers (placed at least 10 years earlier) were recalled. All patients had been followed up annually during this period. Patients were screened for stability of the retainer and for the condition of hard and soft oral tissues...
October 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29344873/laser-capture-microdissection-and-rna-extraction-from-perfusion-fixed-cartilage-and-bone-tissue-from-mice-implanted-with-human-ipsc-derived-mscs-in-a-calvarial-defect-model
#20
Xiaonan Xin, Xi Jiang, Alexander Lichtler, Mark Kronenberg, David Rowe, Joel S Pachter
Laser-capture microdissection (LCM) coupled to downstream RNA analysis poses unique difficulties for the evaluation of mineralized tissues. A rapid protocol was thus developed to enable sufficient integrity of bone and cartilage tissue for reliable sectioning, while minimizing RNA loss associated with prolonged decalcification and purification steps. Specifically, the protocol involves pump-assisted, cardiac perfusion-fixation with paraformaldehyde, and moderate digestion of LCM-acquired tissue with proteinase K followed by DNase treatment and separation of RNA using magnetic beads...
2018: Methods in Molecular Biology
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