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https://www.readbyqxmd.com/read/28340517/piecemeal-mechanism-combining-sprouting-and-intussusceptive-angiogenesis-in-intravenous-papillary-formation-induced-by-pge2-and-glycerol
#1
Lucio Díaz-Flores, Ricardo Gutiérrez, M Del Pino García, Francisco J Sáez, Lucio Díaz-Flores, Juan F Madrid
Recently, we demonstrated that in human intravascular papillary endothelial hyperplasia (IPEH), vein wall vascularization occurs in association with myriad papillae, a large part of which formed in the vascularized vein wall. Previously, using an animal model, we observed that PGE2 and glycerol administration around the femoral vein originates intense vascularization of the vein wall from its intimal endothelial cells (ECs). This vascularization is similar to that in IPEH. The aim of this study is to assess the mechanism of papillary formation, using this model after demonstrating papillary development in neo-vascularized femoral vein walls...
March 24, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28340509/liver-transplant-lt-recipients-with-nonalcoholic-steatohepatitis-nash-have-lower-risk-hepatocellular-carcinoma-hcc
#2
Sara M Lewin, Neil Mehta, R Kate Kelley, John P Roberts, Francis Y Yao, Danielle Brandman
BACKGROUND: Liver transplantation is a well-established treatment for HCC in carefully selected patients. Risk factors for tumors with poor prognostic features on explant have not been well described in a national cohort. METHODS: We performed a retrospective cohort study of adult LT recipients with HCC transplanted from 4/8/12 (when explant pathology in UNOS became available) until 9/30/2014. We evaluated the association between listing diagnosis and other demographic factors with tumor features on explant using logistic regression...
March 24, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28340505/afferent-and-efferent-connections-of-the-interpeduncular-nucleus-with-special-reference-to-circuits-involving-the-habenula-and-raphe-nuclei
#3
Leandro B Lima, Debora Bueno, Fernanda Leite, Stefani Souza, Luciano Gonçalves, Isadora C Furigo, Jose Donato, Martin Metzger
The habenula is an epithalamic structure differentiated into two nuclear complexes, medial (MHb) and lateral habenula (LHb). Recently, MHb together with its primary target, the interpeduncular nucleus (IP), have been identified as major players in mediating the aversive effects of nicotine. However, structures downstream of the MHb-IP axis, including the median (MnR) and caudal dorsal raphe nucleus (DRC), may contribute to the behavioral effects of nicotine. The afferent and efferent connections of the IP have hitherto not been systematically investigated with sensitive tracers...
March 24, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28340503/risk-factors-for-lymph-node-metastases-in-women-with-endometrial-cancer-a-population-based-nation-wide-register-study-on-behalf-of-the-swedish-gynecological-cancer-group-swegcg
#4
K Stålberg, P Kjølhede, M Bjurberg, C Borgfeldt, P Dahm-Kähler, H Falconer, E Holmberg, C Staf, B Tholander, E Åvall-Lundqvist, P Rosenberg, T Högberg
The role of lymphadenectomy in the management of early endometrial cancer is still controversial. In the recent ESMO-ESGO-ESTRO guidelines, lymphadenectomy is recommended for patients with endometrioid adenocarcinoma grade 3 with deep myometrial invasion, but complete agreement was not achieved. In Sweden, DNA aneuploidy has been included as a high-risk factor. The aim of our study was to evaluate the impact of tumor histology, FIGO grade, DNA ploidy and myometrial invasion (MI) on occurrence of lymph node metastasis (LNM) in patients with endometrial cancer...
March 24, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28340469/characterization-and-expression-patterns-of-key-c4-photosynthetic-pathway-genes-in-bread-wheat-triticum-aestivum-l-under-field-conditions
#5
Daoura Goudia Bachir, Iqbal Saeed, Quanhao Song, Tay Zar Linn, Liang Chen, Yin-Gang Hu
Wheat is a C3 plant with relatively low photosynthetic efficiency and is a potential target for C4 photosynthetic pathway engineering. Here we reported the characterization of four key C4 pathway genes and assessed their expression patterns and enzymatic activities at three growth stages in flag leaves of 59 bread wheat genotypes. The C4-like genes homologous to PEPC, NADP-ME, MDH, and PPDK in maize were identified in the A, B, and D sub-genomes of bread wheat, located on the long arms of chromosomes 3 and 5 (TaPEPC), short arms of chromosomes 1 and 3 (TaNADP-ME), long arms of chromosomes 1 and 7 (TaMDH), and long arms of chromosome 1 (TaPPDK), respectively...
March 9, 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/28340455/toxicological-and-behavioral-responses-as-a-tool-to-assess-the-effects-of-natural-and-synthetic-dyes-on-zebrafish-early-life
#6
Flavia R Abe, Jacqueline N Mendonça, Luiz A B Moraes, Gisele A R de Oliveira, Carlos Gravato, Amadeu M V M Soares, Danielle P de Oliveira
Organic dyes extracted from natural sources have been widely used to develop safety and eco-friendly dyes as an alternative to synthetic ones, since the latter are usually precursors of mutagenic compounds. Thereby, toxicity tests to non-target organisms are critical step to develop harmless dyes to environment and in this context, zebrafish early life stages are becoming an important alternative model. We aimed to assess the toxic effects of the synthetic dye Basic Red 51 (BR51, used in cosmetic industry), the natural dye erythrostominone (ERY, a potential commercial dye extracted from fungi) and its photodegradation product (DERY), using zebrafish early life assays...
March 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/28340453/long-term-nitrogen-deposition-increases-heathland-carbon-sequestration
#7
Chris D Field, Chris D Evans, Nancy B Dise, Jane R Hall, Simon J M Caporn
The large increases in reactive nitrogen (N) deposition in developed countries since the Industrial Revolution have had a marked impact on ecosystem functioning, including declining species richness, shifts in species composition, and increased N leaching. A potential mitigation of these harmful effects is the action of N as a fertiliser, which, through increasing primary productivity (and subsequently, organic matter production), has the potential to increase ecosystem carbon (C) storage. Here we report the response of an upland heath to 10years of experimental N addition...
March 21, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28340441/type-d-personality-stress-coping-strategies-and-self-efficacy-as-predictors-of-facebook-intrusion
#8
Agata Błachnio, Aneta Przepiorka, Stanisław Jerzy Czuczwar
Recently, Facebook has become one of the most popular social networking sites. People use it more and more often. A number of studies have recently addressed the issue of excessive Facebook use, showing this phenomenon to be a spreading problem. The main aim of the present study was to examine whether Type D personality, self-efficacy and coping strategies are related to Facebook intrusion. The participants were 882 students of Polish universities, all of them Facebook users (72% women, mean age: 22.25 years, SD =2...
March 14, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28340430/bilateral-sequential-motor-cortex-stimulation-and-skilled-task-performance-with-non-dominant-hand
#9
Milan B Jelić, Saša R Filipović, Sladjan D Milanović, Vuk B Stevanović, Ljubica Konstantinović
OBJECTIVE: To check whether bilateral sequential stimulation (BSS) of M1 with theta burst stimulation (TBS), using facilitatory protocol over non-dominant M1 followed by inhibitory one over dominant M1, can improve skilled task performance with non-dominant hand more than either of the unilateral stimulations do. Both, direct motor cortex (M1) facilitatory non-invasive brain stimulation (NIBS) and contralateral M1 inhibitory NIBS were shown to improve motor learning. METHODS: Forty right-handed healthy subjects were divided into 4 matched groups which received either ipsilateral facilitatory (intermittent TBS [iTBS] over non-dominant M1), contralateral inhibitory (continuous TBS [cTBS] over dominant M1), bilateral sequential (contralateral cTBS followed by ipsilateral iTBS), or placebo stimulation...
March 6, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28340426/porcine-parvovirus-induces-activation-of-nf-%C3%AE%C2%BAb-signaling-pathways-in-pk-15-cells-mediated-by-toll-like-receptors
#10
Liyan Cao, Jianfei Chen, Yanwu Wei, Hongyan Shi, Xin Zhang, Jing Yuan, Da Shi, Jianbo Liu, Xiangdong Zhu, Xin Wang, Shangjin Cui, Li Feng
Porcine parvovirus (PPV) is a pathogenic factor that primarily induces severe reproductive failure of pregnant swine, which results in extensive losses to the swine industry worldwide. In this study, a potential mechanism of PPV-induced activation of the nuclear transcription factor-kappaB (NF-κB) by infection in porcine kidney cells (PK-15) was elucidated for the first time. The subcellular localization of p65 analyzed by immunofluorescence assay (IFA) showed that PPV infection induced p65 translocation from the cytoplasm to the nucleus...
March 21, 2017: Molecular Immunology
https://www.readbyqxmd.com/read/28340421/cannabis-use-patterns-and-motives-a-comparison-of-younger-middle-aged-and-older-medical-cannabis-dispensary-patients
#11
Nancy A Haug, Claudia B Padula, James E Sottile, Ryan Vandrey, Adrienne J Heinz, Marcel O Bonn-Miller
INTRODUCTION: Medical cannabis is increasingly being used for a variety of health conditions as more states implement legislation permitting medical use of cannabis. Little is known about medical cannabis use patterns and motives among adults across the lifespan. METHODS: The present study examined data collected at a medical cannabis dispensary in San Francisco, California. Participants included 217 medical cannabis patients who were grouped into age-defined cohorts (younger: 18-30, middle-aged: 31-50, and older: 51-72)...
March 9, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28340419/photolytic-degradation-of-the-%C3%AE-blocker-nebivolol-in-aqueous-solution
#12
Alaa Salma, Holger V Lutze, Torsten C Schmidt, Jochen Tuerk
Nebivolol (NEB) is one of the top-sold prescription drugs belonging to the third generation of beta-blockers. However, so far, occurrence data in the environment are lacking. Within this study NEB has been found for the first time in effluent samples of wastewater treatment plants in Germany with an average concentration of 13 ng L(-1). Its photodegradation behavior in the environment and in technical processes is largely unknown. To fill this gap, three different UV treatment procedures (UV-C at 254 nm, UV-B at 312 nm and UV-A at 365 nm) were investigated in three different matrices: pure water, pure water in presence of the hydroxyl radical (OH) scavenger tert...
March 13, 2017: Water Research
https://www.readbyqxmd.com/read/28340415/uncertainty-analysis-for-effluent-trading-planning-using-a-bayesian-estimation-based-simulation-optimization-modeling-approach
#13
J L Zhang, Y P Li, G H Huang, B W Baetz, J Liu
In this study, a Bayesian estimation-based simulation-optimization modeling approach (BESMA) is developed for identifying effluent trading strategies. BESMA incorporates nutrient fate modeling with soil and water assessment tool (SWAT), Bayesian estimation, and probabilistic-possibilistic interval programming with fuzzy random coefficients (PPI-FRC) within a general framework. Based on the water quality protocols provided by SWAT, posterior distributions of parameters can be analyzed through Bayesian estimation; stochastic characteristic of nutrient loading can be investigated which provides the inputs for the decision making...
March 6, 2017: Water Research
https://www.readbyqxmd.com/read/28340395/a-quint-wavelength-uv-spectroscopy-for-simultaneous-determination-of-dichlorobenzene-chlorobenzene-and-benzene-in-simulated-water-reduced-by-nanoscale-zero-valent-fe-ni-bimetal
#14
Xiaofang Wan, Yu Liu, Xin-Sheng Chai, Youming Li, Congbao Guo
A quint-wavelength UV spectroscopy for rapid determination of dichlorobenzene (DCB), chlorobenzene (CB) and benzene (B) was developed for the dechlorination process of DCB reduced by nanoscale zero-valent Fe/Ni bimetal. Based on the absorbance measurements at 260, 269, 277, 290 and 300nm, the equations for calculating the concentration of DCB and CB and B were established, in which the spectral interference from the nanoparticles could be effectively minimized. The results show that the present method has a good measurement precision (the relative standard deviations are within 2...
March 18, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28340392/-237-np-analytical-method-using-239-np-tracers-and-application-to-a-contaminated-nuclear-disposal-facility
#15
Mathew S Snow, Samuel S Morrison, Sue B Clark, John E Olson, Matthew G Watrous
Environmental (237)Np analyses are challenged by low (237)Np concentrations and lack of an available yield tracer; we report a rapid, inexpensive (237)Np analytical approach employing the short lived (239)Np (t1/2 = 2.3 days) as a chemical yield tracer followed by (237)Np quantification using inductively coupled plasma-mass spectrometry. (239)Np tracer is obtained via separation from a (243)Am stock solution and standardized using gamma spectrometry immediately prior to sample processing. Rapid digestions using a commercial, 900 W "Walmart" microwave and Parr microwave vessels result in 99...
March 21, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28340368/synthesis-molecular-docking-antimycobacterial-and-antimicrobial-evaluation-of-new-pyrrolo-3-2-c-pyridine-mannich-bases
#16
Gilish Jose, Tholappanavara H Suresha Kumara, Haliwana B V Sowmya, Dharmarajan Sriram, Tayur N Guru Row, Amar A Hosamani, Sunil S More, Bhavya Janardhan, B G Harish, Sandeep Telkar, Yalegara Siddappa Ravikumar
In this report, we describe the synthesis and biological evaluation of a new series of pyrrolo[3,2-c]pyridine Mannich bases (7a-v). The Mannich bases were obtained in good yields by one-pot three component condensation of pyrrolo[3,2-c]pyridine scaffold (6a-c) with secondary amines and excess of formaldehyde solution in AcOH. The chemical structures of the compounds were characterized by (1)H NMR, (13)C NMR, LC/MS and elemental analysis. Single crystal X-ray diffraction has been recorded for compound 7k ([C23H29ClN4](+2), H2O)...
March 16, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28340367/insulin-resistance-is-associated-with-carotid-intima-media-thickness-in-non-diabetic-subjects-a-cross-sectional-analysis-of-the-elsa-brasil-cohort-baseline
#17
Itamar S Santos, Márcio S Bittencourt, Alessandra C Goulart, Maria Inês Schmidt, Maria de Fátima H S Diniz, Paulo A Lotufo, Isabela M Benseñor
BACKGROUND AND AIMS: Epidemiological studies have analyzed the association between carotid intima-media thickness (CIMT) and insulin resistance, glucose levels or glycated hemoglobin with mixed results. We aimed to evaluate the association between CIMT and homeostasis model assessment - insulin resistance (HOMA-IR), fasting and post-load plasma glucose and glycated hemoglobin in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) baseline. METHODS: We included 8028 participants (aged 35-74 years) without diabetes or overt cardiovascular disease who had complete CIMT data at baseline...
March 10, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28340366/effect-of-ezetimibe-on-low-and-high-density-lipoprotein-subclasses-in-sitosterolemia
#18
Rgia A Othman, Semone B Myrie, David Mymin, Jean-Baptiste Roullet, Robert D Steiner, Peter J H Jones
BACKGROUND AND AIMS: Sitosterolemia displays high plasma total sterols [high plant sterols (PS) + normal to high total cholesterol (TC)] with normal to moderately elevated low-density lipoprotein (LDL) levels. High LDL, intermediate-density lipoprotein (IDL) and very low-density lipoprotein (VLDL) particles, low high-density lipoprotein (HDL), and increased non-HDL and the ratios of TC and triglycerides (TG) to HDL can increase the risk for atherosclerosis. Ezetimibe (EZE) can reduce plasma PS and TC levels in sitosterolemia, but its effect on lipoprotein subclasses has not been previously reported...
March 10, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28340365/emotion-regulation-strategies-mediate-the-associations-of-positive-and-negative-affect-to-upper-extremity-physical-function
#19
Mojtaba Talaei-Khoei, Hora Nemati-Rezvani, Stefan F Fischerauer, David Ring, Neal Chen, Ana-Maria Vranceanu
BACKGROUND: The Gross process model of emotion regulation holds that emotion-eliciting situations (e.g. musculoskeletal illness) can be strategically regulated to determine the final emotional and behavioral response. Also, there is some evidence that innate emotional traits may predispose an individual to a particular regulating coping style. METHODS: We enrolled 107 patients with upper extremity musculoskeletal illness in this cross-sectional study. They completed self-report measures of positive and negative affect, emotion regulation strategies (cognitive reappraisal and expressive suppression), upper extremity physical function, pain intensity, and demographics...
March 12, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28340363/benchmark-integral-neutron-experiments-for-fe-be-and-c-with-dt-neutron-by-liquid-scintillation-detector
#20
He Tie, Zheng Pu, Xiao Jun, Zhu Chuanxin, Yang Jian, Guo Haiping
The measurements of iron, beryllium and carbon sphere neutron leakage spectra using BC501A detector by DT neutron source are presented. The experiments were carried out in Institute of Nuclear Physics and Chemistry (INPC), China. Neutron leakage spectra in a wide energy range at angles of 0° and 30° from the direction of incident deuteron beam were obtained. The results show the leakage neutron flux decreases notably with the spherical shell increasing when neutron energy >10MeV. When neutron energy <6MeV the leakage neutron distribution tends to lower energy side with the shell increase...
December 20, 2016: Applied Radiation and Isotopes
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