keyword
https://read.qxmd.com/read/38627770/evaluation-of-network-guided-random-forest-for-disease-gene-discovery
#21
JOURNAL ARTICLE
Jianchang Hu, Silke Szymczak
BACKGROUND: Gene network information is believed to be beneficial for disease module and pathway identification, but has not been explicitly utilized in the standard random forest (RF) algorithm for gene expression data analysis. We investigate the performance of a network-guided RF where the network information is summarized into a sampling probability of predictor variables which is further used in the construction of the RF. RESULTS: Our simulation results suggest that network-guided RF does not provide better disease prediction than the standard RF...
April 16, 2024: BioData Mining
https://read.qxmd.com/read/38627533/comparison-and-evaluation-of-overcoring-and-hydraulic-fracturing-stress-measurements
#22
JOURNAL ARTICLE
Peng Li, Meifeng Cai, Shengjun Miao, Yuan Li, Liang Sun, Jiangtao Wang, Mostafa Gorjian
The stress measurements determined by both the overcoring (OC) and hydraulic fracturing (HF) methods in the Shuichang iron mine and Sanshandao gold mine were compared and evaluated, respectively. The results indicate that the independent OC and HF data in the two mines reveal the same dominant faulting stress regime. The σH orientations derived from the OC and HF methods in the Shuichang iron mine are dominantly oriented in the N81.1°W-N89.4°W and N77.0°E-N88.0°E, respectively, and the σH orientations yielded from the OC and HF techniques in the Sanshandao gold mine are predominantly in the N30°W-N90°W and N55...
April 16, 2024: Scientific Reports
https://read.qxmd.com/read/38627446/spatiotemporal-atmospheric-in-situ-carbon-dioxide-data-over-the-indian-sites-data-perspective
#23
JOURNAL ARTICLE
Mahesh Pathakoti, Mahalakshmi D V, Sreenivas G, Arun Shamrao Suryavanshi, Alok Taori, Yogesh Kant, Raja P, Rajashree Vinod Bothale, Prakash Chauhan, Rajan K S, P R Sinha, Naveen Chandra, Vinay Kumar Dadhwal
In the current study, atmospheric carbon dioxide (CO2 ) data covering multiple locations in the Indian subcontinent are reported. This data was collected using a dedicated ground-based in-situ network established as part of the Geosphere-Biosphere Programme (CAP-IGBP) of the Climate and Atmospheric Processes of the Indian Space Research Organisation (ISRO). Data are collected over Ponmudi, Ooty, Sriharikota, Gadanki, Shadnagar, Nagpur, and Dehradun during 2014-2015, 2017-2020, 2012, 2011-2015, 2014-2017, 2017 and 2008-2011, respectively...
April 16, 2024: Scientific Data
https://read.qxmd.com/read/38627435/a-construction-waste-landfill-dataset-of-two-districts-in-beijing-china-from-high-resolution-satellite-images
#24
JOURNAL ARTICLE
Shaofu Lin, Lei Huang, Xiliang Liu, Guihong Chen, Zhe Fu
Construction waste is unavoidable in the process of urban development, causing serious environmental pollution. Accurate assessment of municipal construction waste generation requires building construction waste identification models using deep learning technology. However, this process requires high-quality public datasets for model training and validation. This study utilizes Google Earth and GF-2 images as the data source to construct a specific dataset of construction waste landfills in the Changping and Daxing districts of Beijing, China...
April 16, 2024: Scientific Data
https://read.qxmd.com/read/38627416/topmed-imputed-genomics-enhances-genomic-atlas-of-the-human-proteome-in-brain-cerebrospinal-fluid-and-plasma
#25
JOURNAL ARTICLE
Heng Yi, Qijun Yang, Charlie Repaci, Cheolmin Matthew Lee, Gyujin Heo, Jigyasha Timsina, Priyanka Gorijala, Chengran Yang, John Budde, Lihua Wang, Carlos Cruchaga, Yun Ju Sung
Comprehensive expression quantitative trait loci studies have been instrumental for understanding tissue-specific gene regulation and pinpointing functional genes for disease-associated loci in a tissue-specific manner. Compared to gene expressions, proteins more directly affect various biological processes, often dysregulated in disease, and are important drug targets. We previously performed and identified tissue-specific protein quantitative trait loci in brain, cerebrospinal fluid, and plasma. We now enhance this work by analyzing more proteins (1,300 versus 1,079) and an almost twofold increase in high quality imputed genetic variants (8...
April 16, 2024: Scientific Data
https://read.qxmd.com/read/38627414/phenomics-and-transcriptomic-profiling-of-fruit-development-in-distinct-apple-varieties
#26
JOURNAL ARTICLE
Weihan Zhang, Yuepeng Han, Liao Liao
Apple is one of the most economically important and popular temperate fruit trees. The domestication of apple has resulted in substantial phenotypic differences, particularly between wild and cultivated varieties. However, the relationship between gene expression and phenotypic variations in apple remains poorly understood. Here, we present a comprehensive dataset featuring five distinct apple varieties, including two wild varieties and three representative cultivated varieties. The dataset comprises of both phenomics data, encompassing twelve fruit quality-related traits continuously measured over two years, and transcriptomic data obtained at different developmental stages with three biological replicates...
April 16, 2024: Scientific Data
https://read.qxmd.com/read/38627408/high-quality-chromosome-level-genome-assembly-of-nicotiana-benthamiana
#27
JOURNAL ARTICLE
Seo-Rin Ko, Sanghee Lee, Hyunjin Koo, Hyojeong Seo, Jaewoong Yu, Yong-Min Kim, Suk-Yoon Kwon, Ah-Young Shin
Nicotiana benthamiana is a fundamental model organism in plant research. Recent advancements in genomic sequencing have revealed significant intraspecific genetic variations. This study addresses the pressing need for a precise genome sequence specific to its geographic origin by presenting a comprehensive genome assembly of the N. benthamiana LAB strain from the Republic of Korea (NbKLAB). We compare this assembly with the widely used NbLAB360 strain, shedding light on essential genomic differences between them...
April 16, 2024: Scientific Data
https://read.qxmd.com/read/38627400/an-eeg-dataset-of-neural-signatures-in-a-competitive-two-player-game-encouraging-deceptive-behavior
#28
JOURNAL ARTICLE
Yiyu Chen, Siamac Fazli, Christian Wallraven
Studying deception is vital for understanding decision-making and social dynamics. Recent EEG research has deepened insights into the brain mechanisms behind deception. Standard methods in this field often rely on memory, are vulnerable to countermeasures, yield false positives, and lack real-world relevance. Here, we present a comprehensive dataset from an EEG-monitored competitive, two-player card game designed to elicit authentic deception behavior. Our extensive dataset contains EEG data from 12 pairs (N = 24 participants with role switching), controlled for age, gender, and risk-taking, with detailed labels and annotations...
April 16, 2024: Scientific Data
https://read.qxmd.com/read/38626821/geomechanics-contribution-to-co-2-storage-containment-and-trapping-mechanisms-in-tight-sandstone-complexes-a-case-study-on-mae-moh-basin
#29
JOURNAL ARTICLE
Romal Ramadhan, Khomchan Promneewat, Vorasate Thanasaksukthawee, Teerapat Tosuai, Masoud Babaei, Seyyed A Hosseini, Avirut Puttiwongrak, Cheowchan Leelasukseree, Suparit Tangparitkul
Recognized as a not-an-option approach to mitigate the climate crisis, carbon dioxide capture and storage (CCS) has a potential as much as gigaton of CO2 to sequestrate permanently and securely. Recent attention has been paid to store highly concentrated point-source CO2 into saline formation, of which Thailand considers one onshore case in the north located in Lampang - the Mae Moh coal-fired power plant matched with its own coal mine of Mae Moh Basin. Despite a large basin and short transport route from the source, target sandstone reservoir buried at deeper than 1000 m is of tight nature and limited data, while question on storing possibility has thereafter risen...
April 14, 2024: Science of the Total Environment
https://read.qxmd.com/read/38626426/self-reported-exposure-to-dust-and-diesel-exhaust-respiratory-symptoms-and-use-of-respiratory-protective-equipment-among-arctic-miners
#30
JOURNAL ARTICLE
David Peyre-Costa, Albin Stjernbrandt, Jens Wahlström, Tiina Maria Ikäheimo, Anje Christina Höper
Arctic miners face significant risks from diesel exhaust and dust exposure, potentially leading to adverse respiratory health. Employers must limit harmful exposures, using personal protective equipment (PPE) as a last line of defense. This study explored the association between reported respiratory exposure and symptoms, and PPE training and usage. Data from the MineHealth study (2012-2014) included a total of 453 Arctic open pit miners in Norway, Sweden, and Finland. Participants answered questions on exposure to dust and diesel exhaust, respiratory symptoms, and PPE use, in addition to age, gender, BMI, smoking, and self-rated health...
December 2024: International Journal of Circumpolar Health
https://read.qxmd.com/read/38626310/comprehensive-safety-profile-of-dipeptidyl-peptidase-4-inhibitors-a-post-marketing-study-based-on-faers-database-using-signal-detection-algorithms
#31
JOURNAL ARTICLE
Dipika Bansal, Beema T Yoosuf, Muhammed Favas Kt, Pinaki Dutta
BACKGROUND: Dipeptidyl peptidase-4 inhibitors (DPP-4 inhibitors) have acquired a foothold in managing type 2 diabetes mellitus, but few concerns have arisen regarding their overall safety profile. The aim of this study is to assess the potential risk of DPP-4 inhibitors by analyzing data from the FDA Adverse Event Reporting System (FAERS) database. RESEARCH DESIGN AND METHODS: This is a retrospective study which explored the FAERS database till March 2023 for the collection of safety reports...
April 16, 2024: Expert Opinion on Drug Safety
https://read.qxmd.com/read/38626055/enhanced-cardiovascular-disease-prediction-modelling-using-machine-learning-techniques-a-focus-on-cardiovitalnet
#32
JOURNAL ARTICLE
Chukwuebuka Joseph Ejiyi, Zhen Qin, Grace Ugochi Nneji, Happy Nkanta Monday, Victor K Agbesi, Makuachukwu Bennedith Ejiyi, Thomas Ugochukwu Ejiyi, Olusola O Bamisile
Aiming at early detection and accurate prediction of cardiovascular disease (CVD) to reduce mortality rates, this study focuses on the development of an intelligent predictive system to identify individuals at risk of CVD. The primary objective of the proposed system is to combine deep learning models with advanced data mining techniques to facilitate informed decision-making and precise CVD prediction. This approach involves several essential steps, including the preprocessing of acquired data, optimized feature selection, and disease classification, all aimed at enhancing the effectiveness of the system...
April 16, 2024: Network: Computation in Neural Systems
https://read.qxmd.com/read/38625891/spatio-temporal-heterogeneity-and-coupling-effect-of-mining-economy-social-governance-and-environmental-conservation-evidence-from-guangxi-zhuang-autonomous-region-china
#33
JOURNAL ARTICLE
Mingkai Liu, Hongyan Zhang, Kaixin Hou, Xiaoju Gong, Changxin Liu
In order to solve the problem of coordinated development among mining economy, social governance and environmental conservation in global resource-based cities, we choose Guangxi Zhuang Autonomous Region as the research area. The advantage of resource endowment and resource industry was measured by location quotient and input-output method. The panel data related to mining governance from 2010 to 2021 were selected to build the evaluation and coupling analysis model between mining economic, social governance and environmental conservation, and the spatial-temporal heterogeneity and coupling effect of them were analyzed by comprehensive empowerment evaluation, spatial autocorrelation analysis and barrier degree methods...
2024: PloS One
https://read.qxmd.com/read/38625247/a-survey-on-differential-privacy-for-medical-data-analysis
#34
REVIEW
WeiKang Liu, Yanchun Zhang, Hong Yang, Qinxue Meng
Machine learning methods promote the sustainable development of wise information technology of medicine (WITMED), and a variety of medical data brings high value and convenience to medical analysis. However, the applications of medical data have also been confronted with the risk of privacy leakage that is hard to avoid, especially when conducting correlation analysis or data sharing among multiple institutions. Data security and privacy preservation have recently played an essential role in the field of secure and private medical data analysis, where many differential privacy strategies are applied to medical data publishing and mining...
June 10, 2023: Ann Data Sci
https://read.qxmd.com/read/38623773/field-method-for-preservation-of-total-mercury-in-waters-including-those-associated-with-artisanal-scale-gold-mining
#35
JOURNAL ARTICLE
David C P King, Michael J Watts, Elliott M Hamilton, Robert J G Mortimer, Mike Coffey, Odipo Osano, Maureene Auma Ondayo, Marcello Di Bonito
Analysis of mercury (Hg) in natural water samples has routinely been impractical in many environments, for example, artisanal and small-scale gold mines (ASGM), where difficult conditions make monitoring of harmful elements and chemicals used in the processes highly challenging. Current sampling methods require the use of hazardous or expensive materials, and so difficulties in sample collection and transport are elevated. To solve this problem, a solid-phase extraction-based method was developed for the sampling and preservation of dissolved Hg in natural water samples, particularly those found around ASGM sites...
April 16, 2024: Analytical Methods: Advancing Methods and Applications
https://read.qxmd.com/read/38623560/riscoper-2-0-a-deep-learning-tool-to-extract-rna-biomedical-relation-sentences-from-literature
#36
JOURNAL ARTICLE
Hailong Zheng, Linfu Xu, Hailong Xie, Jiajing Xie, Yapeng Ma, Yongfei Hu, Le Wu, Jia Chen, Meiyi Wang, Ying Yi, Yan Huang, Dong Wang
RNA plays an extensive role in a multi-dimensional regulatory system, and its biomedical relationships are scattered across numerous biological studies. However, text mining works dedicated to the extraction of RNA biomedical relations remain limited. In this study, we established a comprehensive and reliable corpus of RNA biomedical relations, recruiting over 30,000 sentences manually curated from more than 15,000 biomedical literature. We also updated RIscoper 2.0, a BERT-based deep learning tool to extract RNA biomedical relation sentences from literature...
December 2024: Computational and Structural Biotechnology Journal
https://read.qxmd.com/read/38623547/tripi-a-global-dataset-and-codebase-of-the-total-resources-in-physical-infrastructure-encompassing-road-rail-and-parking
#37
JOURNAL ARTICLE
Martijn van Engelenburg, Sebastiaan Deetman, Tomer Fishman, Paul Behrens, Ester van der Voet
Construction materials are associated with significant environmental and resource impacts. The circular use of materials already in use as stocks may provide an opportunity to reduce these impacts. We provide a dataset describing the potential global urban mine consisting of transportation infrastructure in an open database based on geospatial data from OpenStreetMaps. We reveal the significant opportunities of the embedded materials in this huge stock. With this Total Resources in Physical Infrastructure, or TRIPI, the database we provide easy access to a global dataset covering 175 countries and sub-regions, allowing researchers to select an area of study, and find the location as well as the material composition of the physical infrastructure...
June 2024: Data in Brief
https://read.qxmd.com/read/38623228/data-mining-framework-for-in-depth-quantitative-study-of-influences-on-low-wind-velocity-area-from-morphological-parameters-of-cuboid-form-buildings
#38
JOURNAL ARTICLE
Han Guo, Yehao Song, Yingnan Chu, Yi He, Weizhi Gao, Xiaoqing Guan
Wind environment is important in architectural sustainable design, as existing studies show that it can be considerably influenced by building morphologies. This study aimed to develop a data-mining framework to quantitatively evaluate and compare influences on Low-Wind-Velocity Area (LWVA) of common cuboid-form buildings with typical morphological parameters. The data-mining framework was originally developed by integrating multiple computational methods for rapid in-depth iterative analyses, including the generation of building models using parametric modelling, the big data generation based on hybrid model, and the statistical metric analysis method...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38622212/dynamic-mechanical-response-and-crack-evolution-law-of-raw-coal-loaded-by-dynamic-static-coupling-under-three-dimensional-constraints
#39
JOURNAL ARTICLE
ShunKun Zhao, ShanYang Wei, Lin Zhang, Xianggui Tian, XingZhuan Yang, Xing Wang
This paper presents the investigation of the dynamic mechanical properties of coal rock under complex stress conditions at depth, based on the improved Separate Hopkinson Pressure Bar Test System. A total of 15 groups of coal samples were used to perform dynamic impact tests under different conditions. The changing rules of dynamic strength, crushing, fractal dimension and damage modes of coal under different stress conditions were analyzed. A total of nine groups of coal samples were selected for numerical simulation using ANSYS/LS-DYNA...
April 15, 2024: Scientific Reports
https://read.qxmd.com/read/38621982/-transcriptome-data-mining-combined-with-clinical-and-animal-experiments-for-identification-of-syndrome-element-marker-genes-during-entire-course-of-steroid-induced-osteonecrosis-of-femoral-head
#40
JOURNAL ARTICLE
Qun Li, Zhi-Xing Hu, Yan-Qiong Zhang, Yan Jia, Chao Yang, Li-Li Wang, Jia-Lin Wang, Qian-Qian Yan, Wei-Heng Chen, Na Lin, Chun-Fang Liu
A research strategy combining transcriptome data mining and experimental verification was adopted to identify the marker genes characterizing the syndrome elements of phlegm, stasis, and deficiency in steroid-induced osteonecrosis of the femoral head(SONFH). Firstly, the common differentially expressed gene sets of SONFH with the syndromes of phlegm-stasis obstructing collaterals, vessel obstruction, and liver-kidney deficiency were obtained from the clinical transcriptomic analysis of a previous study. The differential expression trend analysis and functional gene mining were then employed to predict the candidate marker gene sets representing phlegm, stasis, and deficiency...
March 2024: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
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