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https://www.readbyqxmd.com/read/28645214/sodium-fluorescein-facilitates-guided-sampling-of-diagnostic-tumor-tissue-in-nonenhancing-gliomas
#1
Stephen G Bowden, Justin A Neira, Brian J A Gill, Timothy H Ung, Zachary K Englander, George Zanazzi, Peter D Chang, Jorge Samanamud, Jack Grinband, Sameer A Sheth, Guy M McKhann, Michael B Sisti, Peter Canoll, Randy S D'Amico, Jeffrey N Bruce
BACKGROUND: Accurate tissue sampling in nonenhancing (NE) gliomas is a unique surgical challenge due to their intratumoral histological heterogeneity and absence of contrast enhancement as a guide for intraoperative stereotactic guidance. Instead, T2/fluid-attenuated inversion-recovery (FLAIR) hyperintensity on MRI is commonly used as an imaging surrogate for pathological tissue, but sampling from this region can yield nondiagnostic or underdiagnostic brain tissue. Sodium fluorescein is an intraoperative fluorescent dye that has a high predictive value for tumor identification in areas of contrast enhancement and NE in glioblastomas...
June 21, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28645213/cohort-profile-the-bristol-cats-study-bcs-a-birth-cohort-of-kittens-owned-by-uk-households
#2
J K Murray, R A Casey, E Gale, C A T Buffington, C Roberts, R H Kinsman, T J Gruffydd-Jones
No abstract text is available yet for this article.
June 22, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28645208/in-memoriam-john-edward-kalsbeck-md-1928-2017
#3
Daniel H Fulkerson, Andrew Jea, Thomas G Luerssen
No abstract text is available yet for this article.
June 21, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28645194/predictors-of-treatment-response-and-survival-outcomes-in-meningioma-recurrence-with-atypical-or-anaplastic-histology
#4
Muhammad O Chohan, Christopher T Ryan, Ranjodh Singh, Ryan M Lanning, Anne S Reiner, Marc K Rosenblum, Viviane Tabar, Philip H Gutin
BACKGROUND: Recurrence rates for atypical and anaplastic meningiomas range between 9% and 50% after gross total resection and between 36% and 83% after subtotal resection. Optimal treatment of recurrent meningiomas exhibiting atypical/anaplastic histology is complicated because they are often refractory to both surgery and radiation. OBJECTIVE: To evaluate clinical determinants of recurrence and treatment-specific outcomes in patients with recurrent meningiomas exhibiting atypical/anaplastic histology at our institution...
June 21, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28645192/frequent-sexual-activity-predicts-specific-cognitive-abilities-in-older-adults
#5
Hayley Wright, Rebecca A Jenks, Nele Demeyere
Objectives: This study replicates and extends the findings of previous research (Wright, H., & Jenks, R. A. (2016). Sex on the brain! Associations between sexual activity and cognitive function in older age. Age and Ageing, 45, 313-317. doi:10.1093/ageing/afv197) which found a significant association between sexual activity (SA) and cognitive function in older adults. Specifically, this study aimed to generalize these findings to a range of cognitive domains, and to assess whether increasing SA frequency is associated with increasing scores on a variety of cognitive tasks...
June 21, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28645182/stereotactic-radiosurgery-for-brainstem-arteriovenous-malformations-a-multicenter-study
#6
Or Cohen-Inbar, Robert M Starke, Cheng-Chia Lee, Hideyuki Kano, Paul Huang, Douglas Kondziolka, Inga S Grills, Danilo Silva, Mohmoud Abbassy, Symeon Missios, Gene H Barnett, L Dade Lunsford, Jason P Sheehan
BACKGROUND: The management of brainstem arteriovenous malformations (bAVMs) is a formidable challenge. bAVMs harbor higher morbidity and mortality compared to other locations. OBJECTIVE: To review the outcomes following stereotactic radiosurgery (SRS) of bAVMs in a multicenter study. METHODS: Six medical centers contributed data from 205 patients through the International Gamma Knife Research Foundation. Median age was 32 yr (6-81). Median nidus volume was 1...
June 21, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28645169/heterodimerization-of-arabidopsis-calcium-proton-exchangers-contributes-to-regulation-of-guard-cell-dynamics-and-plant-defense-responses
#7
Bradleigh Hocking, Simon J Conn, Murli Manohar, Bo Xu, Asmini Athman, Matthew A Stancombe, Alex R Webb, Kendal D Hirschi, Matthew Gilliham
Arabidopsis thaliana cation exchangers (CAX1 and CAX3) are closely related tonoplast-localized calcium/proton (Ca2+/H+) antiporters that contribute to cellular Ca2+ homeostasis. CAX1 and CAX3 were previously shown to interact in yeast; however, the function of this complex in plants has remained elusive. Here, we demonstrate that expression of CAX1 and CAX3 occurs in guard cells. Additionally, CAX1 and CAX3 are co-expressed in mesophyll tissue in response to wounding or flg22 treatment, due to the induction of CAX3 expression...
June 22, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28645155/features-of-genomic-organization-in-a-nucleotide-resolution-molecular-model-of-the-escherichia-coli-chromosome
#8
William C Hacker, Shuxiang Li, Adrian H Elcock
We describe structural models of the Escherichia coli chromosome in which the positions of all 4.6 million nucleotides of each DNA strand are resolved. Models consistent with two basic chromosomal orientations, differing in their positioning of the origin of replication, have been constructed. In both types of model, the chromosome is partitioned into plectoneme-abundant and plectoneme-free regions, with plectoneme lengths and branching patterns matching experimental distributions, and with spatial distributions of highly-transcribed chromosomal regions matching recent experimental measurements of the distribution of RNA polymerases...
June 22, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28645098/the-behavioral-economics-of-social-anxiety-disorder-reveal-a-robust-effect-for-interpersonal-traits
#9
Thomas L Rodebaugh, Natasha A Tonge, Jaclyn S Weisman, Michelle H Lim, Katya C Fernandez, Ryan Bogdan
Recent evidence suggests that reduced generosity among individuals with social anxiety disorder (SAD) in behavioral economic tasks may result from constraint in changing behavior according to interpersonal contingencies. That is, people with SAD may be slower to be more generous when the situation warrants. Conversely, more global effects on generosity may be related to interpersonal vindictiveness, a dimension only somewhat related to SAD. A total of 133 participants, 73 with the generalized form of SAD, completed self-report instruments and a behavioral economic task with simulated interpersonal (friend, romantic partner, stranger) interactions...
June 15, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28645084/application-of-the-combination-index-ci-isobologram-equation-to-research-the-toxicological-interactions-of-clothianidin-thiamethoxam-and-dinotefuran-in-honeybee-apis-mellifera
#10
Yanmei Liu, Sihong Liu, Hui Zhang, Yanping Gu, Xuesheng Li, Mingyuan He, Huihua Tan
Due to complex pest control scenarios and the needs of agricultural production, different neonicotinoids may be used in certain agricultural applications. Consequently, honeybees may be exposed to these substances through distribution throughout plant tissues via the vascular system through several pathways, such as surface water, the exudates excreted from plants, and air pollution via drift of dust as well as contaminated pollen and nectar. In the current study, the single and combined toxicity of clothianidin, dinotefuran, and thiamethoxam to honeybees was examined after 48 h exposure by the acute oral method and combination index (CI)-isobologram equation...
June 13, 2017: Chemosphere
https://www.readbyqxmd.com/read/28645083/graphene-oxide-nanosheets-induce-dna-damage-and-activate-the-base-excision-repair-ber-signaling-pathway-both-in%C3%A2-vitro-and-in%C3%A2-vivo
#11
Chun-Jiao Lu, Xue-Feng Jiang, Muhammad Junaid, Yan-Bo Ma, Pan-Pan Jia, Hua-Bin Wang, De-Sheng Pei
Graphene oxide (GO) has widespread concerns in the fields of biological sciences and medical applications. Currently, studies have reported that excessive GO exposure can cause cellular DNA damage through reactive oxygen species (ROS) generation. However, DNA damage mediated response of the base excision repair (BER) pathway due to GO exposure is not elucidated yet. Therefore, we exposed HEK293T cells and zebrafish embryos to different concentrations of GO for 24 h, and transcriptional profiles of BER pathway genes, DNA damage, and cell viability were analyzed both in vitro and in vivo...
June 14, 2017: Chemosphere
https://www.readbyqxmd.com/read/28645077/increased-blood-bdnf-in-healthy-individuals-with-a-family-history-of-depression
#12
Ulla Knorr, Mia H Greisen Søndergaard, Pernille Koefoed, Anders Jørgensen, Maria Faurholt-Jepsen, Maj Vinberg, Lars Vedel Kessing
The brain-derive neurotrophic factor (BDNF) may play an important role in the course of depression. We aimed to study the associations between peripheral whole blood BDNF levels in healthy individuals with and without a family history of depression. BDNF levels were significantly increased in healthy individuals with (n = 76), compared with healthy individuals without (n = 39) a family history of depression and persisted after adjustment for age and gender differences. Higher BDNF levels were associated with increasing age and seasonality...
June 17, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28645071/television-viewing-and-risk-of-mortality-exploring-the-biological-plausibility
#13
Mark Hamer, Thomas Yates, Panayotes Demakakos
BACKGROUND AND AIMS: Television (TV) viewing is a major component of leisure sedentary time, and has been consistently associated with cardiovascular disease. We examined the extent to which metabolic biomarkers explain the association between TV viewing and mortality. METHODS: Participants (N = 8,451, aged 64.8 ± 9.9 yrs) were drawn from The English Longitudinal Study of Ageing (ELSA), a national prospective cohort study of community-dwelling men and women living in England...
June 9, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28645055/c-reactive-protein-and-white-blood-cell-levels-in-schizophrenia-bipolar-disorders-and-depression-associations-with-mortality-and-psychiatric-outcomes-a-population-based-study
#14
H T Horsdal, O Köhler-Forsberg, M E Benros, C Gasse
BACKGROUND: Mental disorders have been associated with increased levels of inflammatory markers, which can affect disease trajectories. We aimed to assess levels of C-reactive protein (CRP) and white blood cells (WBC) across individuals with schizophrenia, bipolar disorder, and depression, and to investigate associations with subsequent psychiatric admission and mortality. METHODS: We identified all adults in the Central Denmark Region during 2000-2012 with a first diagnosis of schizophrenia, bipolar disorder, or depression and a baseline measurement of CRP and/or WBC count...
May 17, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28645049/gaseous-elemental-mercury-in-the-marine-boundary-layer-and-air-sea-flux-in-the-southern-ocean-in-austral-summer
#15
Jiancheng Wang, Zhouqing Xie, Feiyue Wang, Hui Kang
Gaseous elemental mercury (GEM) in the marine boundary layer (MBL), and dissolved gaseous mercury (DGM) in surface seawater of the Southern Ocean were measured in the austral summer from December 13, 2014 to February 1, 2015. GEM concentrations in the MBL ranged from 0.4 to 1.9ngm(-3) (mean±standard deviation: 0.9±0.2ngm(-3)), whereas DGM concentrations in surface seawater ranged from 7.0 to 75.9pgL(-1) (mean±standard deviation: 23.7±13.2pgL(-1)). The occasionally observed low GEM in the MBL suggested either the occurrence of atmospheric mercury depletion in summer, or the transport of GEM-depleted air from the Antarctic Plateau...
June 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28645041/behavioral-and-neural-concordance-in-parent-child-dyadic-sleep-patterns
#16
Tae-Ho Lee, Michelle E Miernicki, Eva H Telzer
Sleep habits developed in adolescence shape long-term trajectories of psychological, educational, and physiological well-being. Adolescents' sleep behaviors are shaped by their parents' sleep at both the behavioral and biological levels. In the current study, we sought to examine how neural concordance in resting-state functional connectivity between parent-child dyads is associated with dyadic concordance in sleep duration and adolescents' sleep quality. To this end, we scanned both parents and their child (N=28 parent-child dyads; parent Mage=42...
June 15, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28645033/acetic-acid-assisted-fabrication-of-hierarchical-flower-like-bi2o3-for-photocatalytic-degradation-of-sulfamethoxazole-and-rhodamine-b-under-solar-irradiation
#17
Yueping Bao, Teik-Thye Lim, Ziyi Zhong, Rong Wang, Xiao Hu
With the assistance of acetic acid (CH3COOH), a novel 3D flower-like Bi2O3 was synthesized via hydrothermal process followed by calcination. For the first time, the role of CH3COOH as a capping agent in the formation of flower-like structure was investigated. The as-prepared flower-like Bi2O3 had a high activity on the degradation of sulfamethoxazole (SMX) under simulated solar light irradiation due to the narrow band gap of 2.69eV, high percentage of β-Bi2O3 as well as high intensity of polar facets (120) and (200)...
May 23, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28645017/examining-anxiety-sensitivity-as-a-mediator-of-the-association-between-ptsd-symptoms-and-suicide-risk-among-women-firefighters
#18
Ian H Stanley, Melanie A Hom, Sally Spencer-Thomas, Thomas E Joiner
OBJECTIVE: Posttraumatic stress disorder (PTSD) symptoms are associated with increased suicide risk. Anxiety sensitivity (AS)-the fear of anxiety-related sensations-is both a vulnerability factor for and consequence of PTSD symptoms. AS also predicts suicide risk. To our knowledge, no study has examined whether AS concerns account for the association between PTSD symptoms and suicide risk. METHOD: A total of 254 women firefighters completed a web-based mental health survey...
June 13, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/28645003/structure-and-gene-cluster-of-the-o-antigen-of-enterobacter-cloacae-c4115
#19
Andrei V Perepelov, Guangnan Xu, Andrei V Filatov, Xinjie Zhang, Alexander S Shashkov, Min Wang, Yuriy A Knirel
An O-polysaccharide was isolated by mild acid degradation of the lipopolysaccharide of Enterobacter cloacae C4115 and studied by sugar analysis along with 1D and 2D (1)H and (13)C NMR spectroscopy. The following structure of the linear pentasaccharide repeating unit of the O-polysaccharide was established: →2)-α-l-Rhap-(1 → 2)-α-l-Rhap-(1 → 2)-α-l-Rhap-(1 → 2)-α-d-Galp-(1 → 3)-α-d-FucpNAc-(1→ The O-antigen gene cluster of E. cloacae C4115 was sequenced. The gene functions were tentatively assigned by comparison with sequences in the available databases and found to be in consistence with the O-polysaccharide structure...
June 3, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/28644994/is-the-systematic-circumferential-tumor-cavity-shaving-a-representative-sample-for-the-remaining-mammary-gland-about-75-cases
#20
H Bouzaiene, A Triki, M Ghalleb, M Chemlali, Z Benzarti, J Ben Hassouna, A Gammoudi, K Rahal
INTRODUCTION: The conservative surgery is more and more indicated for breast cancer. However, we still fear local recurrence which is mostly due to residual tumors?. Several techniques have been used to minimize theses residual tumors; one of them is the systematic circumferential tumor cavity shaving (SCTCS). METHODS: We sampled 75 female patients who had conservative surgery with positive shaved margins in the anatomopathology examination and to whom a complementary treatment with mastectomy have been decided...
June 20, 2017: Breast: Official Journal of the European Society of Mastology
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