Raúl Martínez Fernández, Elena Natera Villalba, Rafael Rodriguez-Rojas, Marta Del Álamo, Jose A Pineda-Pardo, Ignacio Obeso, David Mata-Marín, Pasqualina Guida, Tamara Jimenez-Castellanos, Diana Pérez-Bueno, Alicia Duque, Jorge U Máñez Miró, Carmen Gasca-Salas, Michele Matarazzo, Jose A Obeso
BACKGROUND: Unilateral focused ultrasound subthalamotomy (FUS-STN) improves motor features of Parkinson's disease (PD) in moderately advanced patients. The less invasive nature of FUS makes its early application in PD feasible. We aim to assess the safety and efficacy of unilateral FUS-STN in patients with PD of less than 5 years from diagnosis (early PD). METHODS: Prospective, open-label study. Eligible patients with early PD had highly asymmetrical cardinal features...
September 6, 2023: Journal of Neurology, Neurosurgery, and Psychiatry