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Zheng Xu, Jun Ni, Faheem Afzal Shah, Qiaojian Wang, Zhaocheng Wang, Lifang Wu, Songling Fu
Pecan is an economically important nut crop tree due to its unique texture and flavor properties. The pecan seed is rich of unsaturated fatty acid and protein. However, little is known about the molecular mechanisms of the biosynthesis of fatty acids in the developing seeds. In this study, transcriptome sequencing of the developing seeds was performed using Illumina sequencing technology. Pecan seed embryos at different developmental stages were collected and sequenced. The transcriptomes of pecan seeds at two key developing stages (PA, the initial stage and PS, the fast oil accumulation stage) were also compared...
2018: PloS One
Guo-Ming Zhang, Hemant Goyal, Lei-Lei Song
Breast carcinoma is one of the most common types of malignant neoplasms, and is associated with high rates of morbidity and mortality. Altered gene expression is critical in the development of breast cancer. To identify the important differentially expressed genes and microRNAs in breast carcinoma, mRNA (GSE26910, GSE42568, and GSE89116) and microRNA (GSE35412) microarray datasets were downloaded from the Gene Expression Omnibus database. The differentially expressed microRNA expression data were extracted with GEO2R online software...
April 23, 2018: Oncology Reports
Brian M Hoff, Diana C Ford, Dilek Ince, Erika J Ernst, Daniel J Livorsi, Brett H Heintz, Vincent Masse, Michael J Brownlee, Bradley A Ford
Background: Medical applications for mobile devices allow clinicians to leverage microbiological data and standardized guidelines to treat patients with infectious diseases. We report the implementation of a mobile clinical decision support (CDS) application to augment local antimicrobial stewardship. Methods: We detail the implementation of our mobile CDS application over 20 months. Application utilization data were collected and evaluated using descriptive statistics to quantify the impact of our implementation...
2018: Journal of Pathology Informatics
Chao Zhao, Jingchi Jiang, Yi Guan, Xitong Guo, Bin He
OBJECTIVE: Electronic medical records (EMRs) contain medical knowledge that can be used for clinical decision support (CDS). Our objective is to develop a general system that can extract and represent knowledge contained in EMRs to support three CDS tasks-test recommendation, initial diagnosis, and treatment plan recommendation-given the condition of a patient. METHODS: We extracted four kinds of medical entities from records and constructed an EMR-based medical knowledge network (EMKN), in which nodes are entities and edges reflect their co-occurrence in a record...
April 22, 2018: Artificial Intelligence in Medicine
Vanderson Carvalho Fenelon, Juliana Harumi Miyoshi, Camila Sampaio Mangolim, Aline Satomi Noce, Luciana Numata Koga, Graciette Matioli
The study comparatively evaluated diverse strategic models of cyclodextrin (CD) production by the CGTase of Bacillus firmus strain 37: continuous production and repetitive batches in ultrafiltration systems; immobilization of CGTase on curdlan and vegetable sponge natural supports; the use of the glycyrrhizin complexing agent to modulate CGTase selectivity in favor of γ-CD production. All strategies had in common the possibility of separation of CGTase from its inhibitory products and its reuse. In the continuous production model, at 48 h of assay, the highest productivity and selectivity for β-CD were obtained, 1...
July 15, 2018: Carbohydrate Polymers
Santanu Patra, Ekta Roy, Rashmi Madhuri, Prashant K Sharma
No abstract text is available yet for this article.
July 15, 2018: Biosensors & Bioelectronics
Haipeng Diao, Tingting Li, Rong Zhang, Yu Kang, Wen Liu, Yanhua Cui, Shuangyan Wei, Ning Wang, Lihong Li, Haojiang Wang, Weifen Niu, Tijian Sun
Most carbon dots (CDs) conventional fabrication approaches produce single colored fluorescent materials, different methods are required to synthesize distinct carbon dots for specific optical applications. Herein, using one-pot hydrothermal treatment of Syringa obtata Lindl, a facile, low-cost and green assay is achieved in the controllable synthesis of blue and green fluorescent carbon dots. The fluorescent emission of CDs can be well-tuned by adding sodium hydroxide in the precursor solution. Blue fluorescent CDs are applied to Fe3+ sensing with a low detection limit of 0...
April 17, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Tengfei Wu, Peifang Wang, Yanhui Ao, Chao Wang
Photocatalytic water splitting is considered to be a promising strategy for addressing the global energy crisis through the expanded use of solar energy. Herein, cadmium sulfide (CdS) nanorods modified with a thin conductive carbon layer and a nickel phosphide co-catalyst, referred to as cadmium sulfide coated with a carbon layer and nickel phosphide (CdS@C/Ni2 P, where @ indicates a core-shell structure), were synthesized and applied as a novel composite photocatalyst for water splitting. The optimized CdS@C/Ni2 P composite showed a high photocatalytic hydrogen generation rate of 32030 μmol h-1  g-1 , which was approximately 19 times as high as that of pure CdS...
April 18, 2018: Journal of Colloid and Interface Science
Qing Chang, Shanshan Yang, Liuqing Li, Chaorui Xue, Ying Li, Yanzhong Wang, Shengliang Hu, Jinlong Yang, Feng Zhang
A favorable interface for hybrid photocatalysts makes an important contribution in enhancing photocatalytic reactions. Herein we located sulfur and nitrogen co-doped carbon dots (SN-CDs) onto g-C3N4 nanosheets and achieved a novel SN-CD/g-C3N4 composite with a high visible-light photocatalytic reduction of 4-nitrophenol (4-NP). Compared to g-C3N4 nanosheets, the SN-CD/g-C3N4 composite possessed a wider light absorption. More importantly, the interaction of surface groups led to a favorable interfacial bonding between SN-CDs and g-C3N4 nanosheets, which facilitated the transfer of photoexcited electrons and holes, giving rise to an improved electron transport ability of the composite...
April 24, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
Li Wang, Peng Chen, Yu-Cheng Wang, Gui-Shi Liu, Chuan Liu, Xi Xie, Jingzhou Li, Bo-Ru Yang
We report a facile transfer method to fabricate flexible photodetectors directly on tape, wherein the films formed by different processes were integrated together. The tape-based photodetectors with CdS nanowire (NWs) active layers exhibited good performances as those fabricated by conventional processes. The obvious persistent photocurrent (PPC) in our device was eliminated by introducing a conductive polymer poly (3, 4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) onto the CdS NWs layer. By adjusting the concentration of the PEDOT:PSS aqueous solution, a device with a fast response, ultrashort decay time, and relatively large photocurrent was obtained...
April 24, 2018: ACS Applied Materials & Interfaces
Shujin Zhou, Yue Yin, Tingting Yu, Edward J N Stupple, Junlong Luo
The electrophysiological correlates of experiencing novelty in creative advertising were studied in 28 healthy subjects using event-related potentials. Participants viewed images that were difficult to interpret until a description was presented providing either a creative description (CD) featuring an unexpected description of the image based on the original advertisement, or a normal description (ND), which was a literal description of the image (and served as a baseline condition). Participants evaluated the level of creativity of the description...
2018: Frontiers in Psychology
Xiaojin Zhang, Xin Ma, Kang Wang, Shijun Lin, Shitai Zhu, Yu Dai, Fan Xia
Cyclodextrins (CDs), one of the host molecules in supramolecular chemistry, can host guest molecules to form inclusion complexes via non-covalent and reversible host-guest interactions. CD-based light-responsive supramolecular systems are typically constructed using CDs and guest molecules with light-responsive moieties, including azobenzene, arylazopyrazole, o-nitrobenzyl ester, pyrenylmethyl ester, coumarin, and anthracene. To date, numerous efforts have been reported on the topic of CD-based light-responsive supramolecular systems, but these have not yet been highlighted in a separated review...
April 22, 2018: Macromolecular Rapid Communications
Ranju Singh, Nitin Hayaran, Deepika Nagar, Aruna Jain
OBJECTIVE: Preeclampsia or eclampsia is associated with significant maternal morbidity and mortality, and neurological complications are varied. This prospective observational study sought to collect data and push for early aggressive diagnostic evaluation for neurological complications in eclamptic women. METHODS: The study was conducted in Lady Hardinge Medical College and associated Shrimati Sucheta Kriplani Hospital in New Dehli, India from July 2014 to July 2016...
April 19, 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Zhukang Du, Kang Ke, Xueyi Chang, Renfeng Dong, Biye Ren
Superamphiphilic polymers (SAPs) constructed by host-guest inclusion can self-assemble into various nanostructures in solution, which can find applications in many fields such as nanodevices, drug delivery and template synthesis. Herein, we report the controlled self-assembly of multiple-responsive SAP based on a selective host-guest inclusion of β-Cyclodextrin (β-CD) with a modified PEG (FcC11AzoPEG) consisting of a ferrocene (Fc) end group, a C11 alkyl chain, an azobenzene (Azo) block,and a polyethylene glycol (PEG) chain...
April 23, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
Mauro Pedrine Santamaria, Camila Augusto Silveira, Ingrid Fernandes Mathias, Felipe Lucas da Silva Neves, Lúcio Murilo Dos Santos, Maria Aparecida Neves Jardini, Dimitris N Tatakis, Enilson Antônio Sallum, Eduardo Bresciani
BACKGROUND: Gingival recession is frequently associated with non-carious cervical lesion (NCCL) forming a combined defect (CD). The aim of this study was to evaluate a new multidisciplinary protocol for CDs. METHODS: Forty patients presenting 40 Miller's Class I or II gingival recession defects associated with B+ tooth cervical defect were randomly allocated to one of the following treatments: Test Group (n=20), partial restoration of the NCCL, in which the apical border of the restoration was placed 1mm beyond the cement-enamel junction estimation, and connective tissue graft (CTG+PR) and Control Group (n=20), odontoplasty of the NCCL and connective tissue graft (CTG)...
April 22, 2018: Journal of Clinical Periodontology
N Clament Sagaya Selvam, Yeong Gyeong Kim, Dong Jin Kim, Won-Hwa Hong, Woong Kim, Sung Hyuk Park, Wan-Kuen Jo
The efficient photocatalytic degradation of harmful organic pollutants (isoniazid (ISN) and 1,4-dioxane (DX)) via the Z-scheme electron transfer mechanism was accomplished using a photostable composite photocatalyst consisting of BiVO4 , CdS, and reduced graphene oxide (RGO). Compared to their pristine counterparts, the RGO-mediated Z-scheme CdS/BiVO4 (CdS/RGO-BiVO4 ) nanocomposites exhibited superior degradation activities, mainly attributed to the prolonged charge separation. RGO was found to be involved in visible-light harvesting and acted as a solid-state electron mediator at the CdS/BiVO4 interface to realize an effective Z-scheme electron transfer pathway, avoid photocatalyst self-oxidation, and lengthen the life span of charge carriers...
April 19, 2018: Science of the Total Environment
Jinxia Xu, Zhangjun Bai, Fanlin Zu, Fanyong Yan, Junfu Wei, Saihui Zhang, Yunmei Luo
A convenient, highly sensitive and reliable assay for 2,4,6‑trinitrophenol (TNP) and Fe (III) ion (Fe3+ ) in the dual spectroscopic manner is developed based on novel carbon dots (CDs). The CDs with highly blue emitting fluorescent were easily prepared via the one-step potassium hydroxide-assisted reflux method from dextrin. The as-synthesized CDs exhibited the high crystalline quality, the excellent fluorescence characteristics with a high quantum yield of ~13.1%, and the narrow size distribution with an average diameter of 6...
April 10, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Zhongliang Yang, Yongfeng Huang, Yiran Jiang, Yuxi Sun, Yu-Jin Zhang, Pengcheng Luo
Automatically extracting useful information from electronic medical records along with conducting disease diagnoses is a promising task for both clinical decision support(CDS) and neural language processing(NLP). Most of the existing systems are based on artificially constructed knowledge bases, and then auxiliary diagnosis is done by rule matching. In this study, we present a clinical intelligent decision approach based on Convolutional Neural Networks(CNN), which can automatically extract high-level semantic information of electronic medical records and then perform automatic diagnosis without artificial construction of rules or knowledge bases...
April 20, 2018: Scientific Reports
Evan D Baron, Kevin F Lutsky, Mitchell Maltenfort, Pedro Beredjiklian
The purpose of this study was to evaluate the geographic distribution of hand surgeons in the United States. We assessed the states and congressional districts (CDs) for optimal numbers of surgeons, determined whether there is an even distribution, and identified factors influencing practice location. Hand surgeon practice location data from the American Association for Hand Surgery and American Society for Surgery of the Hand (2015) and both state and CD population data from the US Census (2014) were assessed...
April 17, 2018: Journal of Hand Surgery
Marc Hinderer, Melanie Boerries, Martin Boeker, Michael Neumaier, Frank-Peter Loubal, Till Acker, Manfred Brunner, Hans-Ulrich Prokosch, Jan Christoph
BACKGROUND: Pharmacogenomic Clinical Decision Support Systems (CDSS) are considered to be the most feasible tool for adopting pharmacogenomic testing into clinical routine. OBJECTIVE: To discuss important factors for implementing pharmacogenomic CDSS into German hospitals. METHODS: We analyzed two relevant studies. Furthermore, we interviewed data privacy officers of three German university hospitals and examined relevant legal regulations in literature...
2018: Studies in Health Technology and Informatics
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