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https://www.readbyqxmd.com/read/29457866/epigenetic-effects-of-metformin-from-molecular-mechanisms-to-clinical-implications
#1
REVIEW
S C Bridgeman, G C Ellison, P E Melton, P Newsholme, Cds Mamotte
There is a growing body of evidence that links epigenetic modifications to type 2 diabetes. Researchers have more recently investigated effects of commonly used medications, including those prescribed for diabetes, on epigenetic processes. This work reviews the influence of the widely used antidiabetic drug metformin on epigenomics, microRNA levels and subsequent gene expression and potential clinical implications. Metformin may influence the activity of numerous epigenetic modifying enzymes, mostly via modulating the activation of AMP-activated protein kinase (AMPK)...
February 19, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29457808/cds-nanosphere-decorated-hollow-polyhedral-zco-derived-from-a-metal-organic-framework-mof-for-effective-photocatalytic-water-evolution
#2
Wenxia Chen, Jiasheng Fang, Yiwei Zhang, Guangliang Chen, Shuo Zhao, Chao Zhang, Ran Xu, Jiehua Bao, Yuming Zhou, Xin Xiang
Semiconductor nanostructures have received considerable attention in the field of photocatalytic hydrogen evolution. However, eco-friendly, high efficiency, and low-cost semiconductor materials are still desired. In consideration of this, herein, we design a new and economic noble-metal-free CdS/Znx Co3-x O4 (CdS/ZCO) nanohybrid photocatalyst using a metal-organic framework (MOF) template, which is a framework structure composed of organic ligands and metal ion nodes with different numbers of connections. The as-prepared CdS/ZCO composites with a large specific surface area and porous hollow structure exhibit remarkable catalytic activity and high stability for hydrogen generation...
February 19, 2018: Nanoscale
https://www.readbyqxmd.com/read/29455540/cds-nanoparticles-of-different-lengths-induce-differential-responses-in-some-of-the-liver-functions-of-mice
#3
Q Z Li, J Sun, H T Shen, S F Jia, D S Bai, D Ma
Cadmium sulfide nanoparticles (CdS NPs) are one of important nanoparticle materials which are widely used in photoelectric production, but their potential health hazard to the liver is not clear. This study is aimed at exploring the possible mechanisms of liver injury induced by CdS NPs. Male mice were treated with nanoparticles of 110-130 nm and 80-100 nm cadmium sulfide. The main methods were based on detecting the vigor of superoxide dismutase (SOD) and glutathione (GSH), and content of malondialdehyde (MDA) in both blood and liver tissues as well as on observing the pathological changes in liver tissue...
2018: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/29453104/controlling-shape-anisotropy-of-hexagonal-cds-for-highly-stable-and-efficient-photocatalytic-h-2-evolution-and-photoelectrochemical-water-splitting
#4
Yongjin Ma, Yi Liu, Yuan Bian, Anquan Zhu, Yang Yang, Jun Pan
Photocorrosion and low solar conversion efficiency hindered widely applications of CdS in photocatalytic (PC) H 2 evolution and photoelectrochemical (PEC) water splitting. Hence, this work reports the shape anisotropy of hexagonal CdS possesses highly stable and efficient PC H 2 evolution and PEC water splitting by simply mixed diethylenetriamine (DETA) and deionized water (DIW) solvothermal. Here we demonstrate that the shape of hexagonal CdS plays an important role in their PC activity. The CdS-Nanorod yields optimal 5...
February 6, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29452230/a-regulatory-circuitry-between-mir-193a-mir-600-and-wt1-enhances-leukemogenesis-in-acute-myeloid-leukemia
#5
Haiying Li, Chongyun Xing, Bin Zhou, Haige Ye, Jianhua Feng, Jianbo Wu, Shenmeng Gao
The aberrant overexpression of the Wilm's tumor-1 (WT1) in acute myeloid leukemia (AML) plays an important role in blast cell survival through enhancing proliferation and inhibiting apoptosis. However, the mechanism underlying the overexpression of WT1 remains unclear. Here, we identified miR-193a (miR-193a-5p) and miR-600 targeting and degrading WT1. MiR-193a and miR-600 synergistically reduced WT1 expression and suppressed the activity of a luciferase reporter through binding coding sequence (CDS) and 3'-untranslated regions (3'UTR) of WT1 mRNA, respectively...
February 13, 2018: Experimental Hematology
https://www.readbyqxmd.com/read/29448945/rna-secondary-structure-profiling-in-zebrafish-reveals-unique-regulatory-features
#6
Kriti Kaushik, Ambily Sivadas, Shamsudheen Karuthedath Vellarikkal, Ankit Verma, Rijith Jayarajan, Satyaprakash Pandey, Tavprithesh Sethi, Souvik Maiti, Vinod Scaria, Sridhar Sivasubbu
BACKGROUND: RNA is known to play diverse roles in gene regulation. The clues for this regulatory function of RNA are embedded in its ability to fold into intricate secondary and tertiary structure. RESULTS: We report the transcriptome-wide RNA secondary structure in zebrafish at single nucleotide resolution using Parallel Analysis of RNA Structure (PARS). This study provides the secondary structure map of zebrafish coding and non-coding RNAs. The single nucleotide pairing probabilities of 54,083 distinct transcripts in the zebrafish genome were documented...
February 15, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29448673/a-phosphine-free-route-to-size-adjustable-cdse-and-cdse-cds-core-shell-quantum-dots-for-white-light-emitting-diodes
#7
Yugang Zhang, Guopeng Li, Ting Zhang, Zihang Song, Hui Wang, Zhongping Zhang, Yang Jiang
The selenium dioxide was used as the precursor to synthesize wide-size-ranged CdSe quantum dots (2.4-5.7 nm) via hot-injection route. The CdSe quantum dots are featured with high crystalline, monodisperse, zinc blende structure and wide emission region (530-635 nm). In order to improve the stability and quantum yield, a phosphine-free single-molecular precursor approach is used to obtain CdSe/CdS core/shell quantum dots. The CdSe/CdS quantum dots are highly fluorescent with quantum yield up to 65%, and persist the good monodispersity and high crystallinity...
March 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448594/conduction-mechanisms-in-polyvinyl-alcohol-cds-cds-cu-nanoparticle-hybrid-nanocomposites
#8
Sweety Sarma, Bakang Moses Mothudi, Mokhotjwa Simon Dhlamini, Sekhar Chandra Ray
The electrical conduction mechanisms were investigated for the CdS and Cu-doped CdS (CdS:Cu) nanoparticles embedded in polyvinyl alcohol (PVA) (PVA/CdS and PVA/CdS:Cu) nanocomposites; synthesized by the chemical Sol Gel method on indium tin-oxide (ITO) substrate. X-ray diffraction pattern results show that the PVA/CdS nanocomposite is hawleyite-sturcture and PVA/CdS:Cu nanocomposites show greenockite-hawelyite mixed structure. The sizes of CdS and CdS:Cu nanoparticles were estimated from transmission electron microscopy (TEM) images and are ≈4 nm and ≈10 nm respectively; which were formed inside the PVA polymer layer...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448589/photocurrent-enhancement-of-cdse-quantum-dot-sensitized-solar-cells-incorporating-single-walled-carbon-nanotubes
#9
Jonghee Yang, Jongtaek Lee, Junyoung Lee, Taehun Park, Whikun Yi
We demonstrate quantum-dot sensitized solar cells (QDSSCs) which have colloidal CdSe quantum dots (TOPO-CdSe) as a sensitizer onto mesoporous TiO2 photoanodes. CdS quantum-dot (QD) layer plays a role of buffer layer for direct adsorption of TOPO-CdSe. We incorporate single-walled carbon nanotubes with TiO2 photoanode of our QDSSCs to facilitate efficient charge transfer. Shortcircuit current densities (Jsc) of our QDSSCs are enhanced while other parameters are maintained. Furthermore, we apply inert N2 pressure onto our sensitized photoanodes and observe 44% of Jsc enhancement with respect to pristine sample...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448532/fabrication-of-a-hierarchical-tio%C3%A2-microsphere-carbon-dots-photocatalyst-for-oxygen-evolution-and-dye-degradation-under-visible-light
#10
Soumen Chandra, Karunamay Majee, Triveni Kumar Mahto, Sumanta Kumar Padhi, Sumanta Kumar Sahu
Anatase hierarchical TiO2 microsphere/carbon dots composite (HTM/CDs) was fabricated by a facile method for active visible light photocatalysis. The phase, morphology, microstructure and optical properties were investigated by X-ray diffraction, scanning electronmicroscopy, transmission electron microscopy and UV-VIS diffuse reflectance spectroscopy respectively. Under visible light illumination, the fabricated HTM/CDs composite was exhibited an enhanced photo catalytic activity compared to that of pure hierarchical TiO2 microspheres (HTM)...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29446775/carbon-dots-with-efficient-solid-state-red-light-emission-through-the-step-by-step-surface-modification-towards-light-emitting-diodes
#11
Jinyang Zhu, Xue Bai, Xu Chen, Zhifeng Xie, Yongsheng Zhu, Gencai Pan, Yue Zhai, Hanzhuang Zhang, Biao Dong, Hongwei Song
Carbon dots (CDs) have attracted extensive attention over the past decade due to their excellent advantages. However, few attempts have been reported for realizing the long-wavelength emission, especially for obtaining efficient solid-state red emission with high photoluminescence quantum yield (QY). Herein, we developed highly red light emitting CDs by the step-by-step surface modifications of the nitrogen-doped CDs. By introducing hexadecyltrimethyl ammonium bromide to modulate a red CD aqueous solution, the photoluminescence QY increases from 23...
February 15, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29445645/evaluating-the-effect-of-using-training-cds-on-the-patients-with-type-ii-diabetes
#12
Hamid Taghinejad, Hamed Tavan
No abstract text is available yet for this article.
February 2018: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29443903/qlog-solar-cell-mode-photodiode-logarithmic-cmos-pixel-using-charge-compression-and-readout
#13
Yang Ni
In this paper, we present a new logarithmic pixel design currently under development at New Imaging Technologies SA (NIT). This new logarithmic pixel design uses charge domain logarithmic signal compression and charge-transfer-based signal readout. This structure gives a linear response in low light conditions and logarithmic response in high light conditions. The charge transfer readout efficiently suppresses the reset (KTC) noise by using true correlated double sampling (CDS) in low light conditions. In high light conditions, thanks to charge domain logarithmic compression, it has been demonstrated that 3000 electrons should be enough to cover a 120 dB dynamic range with a mobile phone camera-like signal-to-noise ratio (SNR) over the whole dynamic range...
February 14, 2018: Sensors
https://www.readbyqxmd.com/read/29442967/2d-effective-electron-mass-at-the-fermi-level-in-accumulation-and-inversion-layers-of-mosfet-nano-devices
#14
S L Singh, S B Singh, K P Ghatak
In this paper an attempt is made to study the 2D Fermi Level Mass (FLM) in accumulation and inversion layers of nano MOSFET devices made of nonlinear optical, III-V, ternary, Quaternary, II-VI, IV-VI, Ge and stressed materials by formulating 2D carrier dispersion laws on the basis of <mml:math display="block"> <mml:mover accent="true"> <mml:mi>k</mml:mi> <mml:mo>→</mml:mo> </mml:mover> <mml:mo>⋅</mml:mo> </mml:math> <mml:math display="block"> <mml:mover accent="true"> <mml:mi>p</mml:mi> <mml:mo>→</mml:mo> </mml:mover> <mml:mo>⋅</mml:mo> </mml:math> formalism and considering the energy band constants of a particular material...
April 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442944/photoluminescence-quenching-based-visual-and-spectroscopic-method-for-mercury-sensing-by-surface-modified-cadmium-sulphide-quantum-dots
#15
Ambika Kumar, R K Dutta
Here we present a simple yet efficient analytical method for sensing ultratrace levels of Hg2+ ions by highly water soluble CdS quantum dots functionalized with thiourea as a probe. The bluish photoluminescence emission of the probe responded to a systematic linear photoluminescence quenching in the presence of increasing concentration of Hg2+ ions. The photoluminescence quenching by Hg2+ ions was attributed to agglomeration of the quantum dots, which has been confirmed by zeta potential measurements. The sensitivity (31...
April 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442892/facile-synthesis-of-near-infrared-emissive-cds-quantum-dots-for-live-cells-imaging
#16
Yanyan Cui, Chunfang Zhang, Li Song, Jian Yang, Zhongbo Hu, Xiangfeng Liu
CdS quantum dots (QDs) have attracted extensive attention owing to their great potential in optoelectronic nanodevices and biosensors. But their poor water solubility and high cytotoxicity restrict their practical application in live cell imaging. In addition, CdS QDs usually emit blue or green fluorescence, which also have some limitations for cell imaging due to the "water window" effect. In this study, we report a novel strategy to directly synthesize water-soluble and low-cytotoxic CdS QDs with near infrared (NIR) fluorescence through confinement into BSA templates with the mediation of L-cysteine (Cys)...
April 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442888/synthesis-and-characteristics-of-large-area-and-high-filling-cds-nanowire-arrays-in-aao-template
#17
Xiao-Yi Lv, Jun-Wei Hou, Zhi-Xian Gao, Hong-Fei Liu
CdS nanowires arrays were successfully synthesized by a simple solvothermal process using AAO as templates. The phase structures, morphologies, and optical properties of the products were investigated by X-ray diffraction, scanning electron microscopy, high-resolution transmission electron microscopy, Raman spectroscopy, and photoluminescence spectroscopy. It was found that the nanowires were composed of hexagonal structure CdS nanoparticles and the average diameters is about 60-70 nm. A strong green emission with a maximum around 505 nm was observed from the synthesized CdS nanowires at room temperature, which was attributed to near-band-edge emission...
May 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442762/high-quality-nitrogen-and-silicon-co-doped-carbon-dots-n-si-cds-for-fe-3-sensing
#18
Jinzhu Wu, Yaxiu Feng, Yanbin Shao, Yanchun Sun
Nitrogen and silicon co-doped carbon nanodots (N/Si-CDs) were synthesized by one-step hydrothermal carbonization of folic acid and 3-aminopropyl trimethoxy silane with the assistance of glycerol. The resultant N/Si-CDs present intense excitation-independent photoluminescence (PL) emission owing to their monodisperse sizes and specific surface states. In comparison to nitrogen single doped CDs (N-CDs), the co-doped N/Si-CDs possess better PL properties following different emission manner due to the synergistic effects of the nitrogen and silicon dopants...
June 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442654/highly-efficient-visible-light-driven-graphene-cds-nanocomposite-photocatalysts
#19
Qian Zhao, Ruifeng Liu, Yalong Shen, Minglan Fang, Mingfeng Dong
Graphene-CdS nanocomposites with different CdS contents were synthesized via a solvothermal route. Compared with pure CdS, graphene-CdS composites exhibited higher efficiency in photodegradation of methylene blue (MB) under visible light irradiation. TEM observations demonstrated that a homogeneous distribution of CdS nanoparticles on the graphene nanosheets was formed, while the CdS nanoparticles on graphene-CdS composite (1 g/7.5 mmol) distributed best among graphene-CdS composites. The results show that the graphene-CdS composite (1 g/7...
July 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442648/the-preparation-and-optical-properties-of-ni-ii-and-mn-ii-doped-in-znte-nanobelt-nanorod-by-using-chemical-vapor-deposition
#20
Arfan Bukhtiar, Zou BingSuo
The doping techniques are often used to modify the properties of semiconductors. Transition metal ion doping in semiconductor can lead to dilute magnetic semiconductors (DMSs), which may initiate some novel properties related to spins. In contrast to the wide band semiconductor ZnO, ZnSe and CdS crystal the transition metal (TM) ion aggregate can be the origin of the ferromagnetic behaviors, which influence their optical properties mainly through the exciton-spin interactions due to their high exciton binding energy...
July 1, 2018: Journal of Nanoscience and Nanotechnology
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