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Keith Rourke
No abstract text is available yet for this article.
May 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Keith Francis Rourke, Andrew E MacNeily
INTRODUCTION: Urology residency training in Canada is quickly evolving from a time-based to a competency-based model. We aim to better define core surgical competencies that would comprise a surgical curriculum and assess any discrepancies in opinion nationally. METHODS: A web-based survey was validated and sent to the 536 practicing members of the Canadian Urological Association (CUA) in August and October 2014. The survey consisted of questions regarding practice demographics, fellowship training, and evaluated the 76 most common urological procedures (using a five-point Likert scale) in the context of the question, "After completion of residency training in Canada a urologist should be proficient in…" A core procedure was defined as one for which there was ≥75% agreement...
May 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Nathan Y Hoy, Keith F Rourke
OBJECTIVES: To describe the spectrum of adult presentations with hypospadias-related complications and examine the effect of childhood surgical repair on these adult presentations. METHODS: A retrospective chart review over a 10-year period, from Aug. 2004-Dec. 2014, demonstrated 93 adult patients who presented to a reconstructive urologist with complications related to hypospadias. Patients were divided into two groups: those with no prior hypospadias surgery (Group 1, N=19) and those who underwent surgical correction as a child (Group 2, N=74)...
September 27, 2016: Urology
Liam Rourke, Leanna Cruickshank, Larissa Shapke, Anthony Singhal
Researchers have identified a component of the EEG that discriminates visual experts from novices. The marker indexes a comprehensive model of visual processing, and if it is apparent in physicians, it could be used to investigate the development and training of their visual expertise. The purpose of this study was to determine whether a neural marker of visual expertise-the enhanced N170 event-related potential-is apparent in the EEGs of physicians as they interpret diagnostic images. We conducted a controlled trial with 10 cardiologists and 9 pulmonologists...
September 23, 2016: Advances in Health Sciences Education: Theory and Practice
Feng Zhu, Michael J Rourke, Tianyi Yang, Jacob Rodriguez, Maciej A Walczak
We demonstrate that configurationally stable anomeric stannanes undergo a stereospecific cross-coupling reaction with aromatic halides in the presence of a palladium catalyst with exceptionally high levels of stereocontrol. In addition to a broad substrate scope (>40 examples), this reaction eliminates critical problems inherent to nucleophilic displacement methods and is applicable to (hetero)aromatics, peptides, pharmaceuticals, common monosaccharides, and saccharides containing free hydroxyl groups.
September 21, 2016: Journal of the American Chemical Society
Charles Boelen, David Pearson, Arthur Kaufman, James Rourke, Robert Woollard, David C Marsh, Trevor Gibbs
Health systems worldwide are confronted with challenges due to increased demand from their citizens, an aging population, a variety of health risks and limited resources. Key health stakeholders, including academic institutions and medical schools, are urged to develop a common vision for a more efficient and equitable health sector. It is in this environment that Boelen and Heck defined the concept of the "Social Accountability of Medical Schools" - a concept that encourages schools to produce not just highly competent professionals, but professionals who are equipped to respond to the changing challenges of healthcare through re-orientation of their education, research and service commitments, and be capable of demonstrating a positive effect upon the communities they serve...
September 9, 2016: Medical Teacher
Samantha Robinson, Sandra Gardner, Mona Loutfy, Lucia Light, Wangari Tharao, Sean B Rourke, Ann N Burchell
Understanding the sexual activities and partnerships of women living with human immunodeficiency virus (HIV) remains important to promote healthy sexuality and to reduce the transmission of HIV and other sexually transmitted infections. We described sexual behaviors of women living with HIV enrolled in an ongoing study in Ontario, Canada. Data were available from 582 women who self-completed a sexual behavior questionnaire between 2010 and 2012. Nearly half (46.1%) of women reported a sexual partner in the preceding three months; women less likely to be sexually active were older, Black/African, separated, divorced, widowed, single, and unemployed...
September 8, 2016: AIDS Care
Hannah M OʼRourke, Kimberly D Fraser
Recommendations for the evaluation of quality improvement interventions have been made in order to improve the evidence base of whether, to what extent, and why quality improvement interventions affect chosen outcomes. The purpose of this article is to articulate why these recommendations are appropriate to improve the rigor of quality improvement intervention evaluation as a research endeavor, but inappropriate for the purposes of everyday quality improvement practice. To support our claim, we describe the differences between quality improvement interventions that occur for the purpose of practice as compared to research...
September 2016: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
Trevor Haines, Keith F Rourke
PURPOSE: To prospectively assess the effect of urethral transection on erectile function after anterior urethroplasty. METHODS: From February 2012 to December 2014, 104 patients were enrolled in a prospective study assessing erectile function (EF) after anterior urethroplasty. Participants completed the International Index of Erectile Function (IIEF) questionnaire preoperatively and 6 months postoperatively. Outcome measures were the incidence of erectile dysfunction (ED) defined by ≥5-point change in EF and mean change in the EF domain...
August 25, 2016: World Journal of Urology
Daniel G Beach, Callee M Walsh, Pamela Cantrell, Wade Rourke, Sinead O'Brien, Kelley Reeves, Pearse McCarron
RATIONALE: Domoic acid (DA) is a potent neurotoxin that accumulates in shellfish. Routine testing involves homogenization, extraction and chromatographic analysis, with a run time of up to 30 min. Improving throughput using ambient ionization for direct analysis of DA in tissue would result in significant time savings for regulatory testing labs. METHODS: We assess the suitability of laser ablation electrospray ionization high-resolution mass spectrometry (LAESI-HRMS) for high-throughput screening or quantitation of DA in a variety of shellfish matrices...
November 30, 2016: Rapid Communications in Mass Spectrometry: RCM
Hunter Wessells, Keith W Angermeier, Sean Elliott, Christopher M Gonzalez, Ron Kodama, Andrew C Peterson, James Reston, Keith Rourke, John T Stoffel, Alex J Vanni, Bryan B Voelzke, Lee Zhao, Richard A Santucci
PURPOSE: The purpose of this Guideline is to provide a clinical framework for the diagnosis and treatment of male urethral stricture. MATERIALS AND METHODS: A systematic review of the literature using the Pubmed, Embase, and Cochrane databases (search dates 1/1/1990 to 12/1/2015) was conducted to identify peer-reviewed publications relevant to the diagnosis and treatment of urethral stricture. The review yielded an evidence base of 250 articles after application of inclusion/exclusion criteria...
August 3, 2016: Journal of Urology
Aranka Anema, Sarah J Fielden, Susan Shurgold, Erin Ding, Jennifer Messina, Jennifer E Jones, Brian Chittock, Ken Monteith, Jason Globerman, Sean B Rourke, Robert S Hogg
OBJECTIVE: People living with HIV in high-resource settings suffer severe levels of food insecurity; however, limited evidence exists regarding dietary intake and sub-components that characterize food insecurity (i.e. food quantity, quality, safety or procurement) in this population. We examined the prevalence and characteristics of food insecurity among people living with HIV across British Columbia, Canada. DESIGN: This cross-sectional analysis was conducted within a national community-based research initiative...
2016: PloS One
Tyler J O'Neill, Janet M Raboud, Jill Tinmouth, Sean B Rourke, Sandra Gardner, Curtis Cooper, Sergio Rueda, Trevor A Hart, Anita Rachlis, Ann N Burchell
In the modern antiretroviral (ARV) era, there is limited knowledge about the prevalence and risk factors for HIV patient-reported gastrointestinal (GI) symptoms (diarrhoea/soft stool, nausea/vomiting, bloating/painful abdomen, loss of appetite, and weight loss/wasting) and distress. We prospectively analysed data (2007-2014) on distressing GI symptoms from the Ontario HIV Treatment Network Cohort Study, which follows people attending HIV clinics. Using generalized estimating equations with a logit link, we estimated the associations of psychosocial, demographic, behavioural, and clinical factors with each GI symptoms compared to asymptomatic and non-bothersome symptoms...
July 25, 2016: AIDS Care
Mariateresa Maldini, Mario Chessa, Giacomo L Petretto, Paola Montoro, Jonathan P Rourke, Marzia Foddai, Marcello Nicoletti, Giorgio Pintore
INTRODUCTION: Myrtus communis L. (Myrtaceae) is a self-seeded shrub, widespread in Sardinia, with anti-inflammatory, antiseptic, antimicrobial, hypoglycemic and balsamic properties. Its berries, employed for the production of sweet myrtle liqueur, are characterised by a high content of bioactive polyphenols, mainly anthocyanins. Anthocyanin composition is quite specific for vegetables/fruits and can be used as a fingerprint to determine the authenticity, geographical origin and quality of raw materials, products and extracts...
September 2016: Phytochemical Analysis: PCA
Sergio Rueda, Sanjana Mitra, Shiyi Chen, David Gogolishvili, Jason Globerman, Lori Chambers, Mike Wilson, Carmen H Logie, Qiyun Shi, Sara Morassaei, Sean B Rourke
OBJECTIVE: To conduct a systematic review and series of meta-analyses on the association between HIV-related stigma and health among people living with HIV. DATA SOURCES: A structured search was conducted on 6 electronic databases for journal articles reporting associations between HIV-related stigma and health-related outcomes published between 1996 and 2013. STUDY ELIGIBILITY CRITERIA: Controlled studies, cohort studies, case-control studies and cross-sectional studies in people living with HIV were considered for inclusion...
2016: BMJ Open
Ryan Ng, Claire E Kendall, Ann N Burchell, Ahmed M Bayoumi, Mona R Loutfy, Janet Raboud, Richard H Glazier, Sean Rourke, Tony Antoniou
BACKGROUND: Emergency department use may reflect poor access to primary care. Our objective was to compare rates and causes of emergency department use between adults living with and without HIV. METHODS: We conducted a population-based study involving Ontario residents living with and without HIV between Apr. 1, 2011, and Mar. 31, 2012. We frequency matched adults with HIV to 4 HIV-negative people by age, sex and census division, and used random-effects negative binomial regression to compare rates of emergency department use...
April 2016: CMAJ Open
Keith F Rourke
No abstract text is available yet for this article.
August 2016: Urology
Erin K McGuirk, Christopher J Lundstrum, Morgan R Betker, Zachary T Rourk, Katelyn E Uithoven, Emma J Lee, Eric M Snyder
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Christopher J Lundstrom, Morgan R Betker, Erin K McGuirk, Katelyn E Uithoven, Zachary T Rourk, Emma J Lee, Eric M Snyder
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Paul A Shaw, Jessica M Phillips, Guy J Clarkson, Jonathan P Rourke
The oxidation of three different complexes of the doubly cycloplatinated 2,6-di(4-fluorophenyl)pyridine ligand (namely DMSO, PPh3 and PPr3 derivatives, 1a, 1b and 1c, respectively) with the electrophilic oxidant iodobenzenedichloride was studied. In each case oxidation can yield a simple trans-dichloro platinum(iv) complex (2(t)), which subsequently isomerises to the cis isomer (2(c)). However, by changing the solvent, or performing the reaction in the presence of an additional ligating species, a five-coordinate intermediate can be trapped out and isolated...
July 28, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
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