keyword
MENU ▼
Read by QxMD icon Read
search

Rourke

keyword
https://www.readbyqxmd.com/read/29216222/cortical-computations-via-transient-attractors
#1
Oliver L C Rourke, Daniel A Butts
The ability of sensory networks to transiently store information on the scale of seconds can confer many advantages in processing time-varying stimuli. How a network could store information on such intermediate time scales, between typical neurophysiological time scales and those of long-term memory, is typically attributed to persistent neural activity. An alternative mechanism which might allow for such information storage is through temporary modifications to the neural connectivity which decay on the same second-long time scale as the underlying memories...
2017: PloS One
https://www.readbyqxmd.com/read/29209931/co-morbid-non-communicable-diseases-and-associated-health-service-use-in-african-and-caribbean-immigrants-with-hiv
#2
Khatundi-Irene Masindi, Nathaniel Jembere, Claire E Kendall, Ann N Burchell, Ahmed M Bayoumi, Mona Loutfy, Janet Raboud, Sean B Rourke, Henry Luyombya, Tony Antoniou
We sought to characterize non-communicable disease (NCD)-related and overall health service use among African and Caribbean immigrants living with HIV between April 1, 2010 and March 31, 2013. We conducted two population-based analyses using Ontario's linked administrative health databases. We studied 1525 persons with HIV originally from Africa and the Caribbean. Compared with non-immigrants with HIV (n = 11,931), African and Caribbean immigrants had lower rates of hospital admissions, emergency department visits and non-HIV specific ambulatory care visits, and higher rates of health service use for hypertension and diabetes...
December 5, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29194669/red-blood-cell-transfusion-in-adult-palliative-care-a-systematic-review
#3
REVIEW
Nicolas Chin-Yee, Joshua Taylor, Kaitlyn Rourke, Danika Faig, Alexandra Davis, Dean Fergusson, Elianna Saidenberg
BACKGROUND: The risks and benefits of red blood cell (RBC) transfusion in palliative care patients remain poorly understood. We reviewed the literature to summarize available information on RBC transfusion in this population. STUDY DESIGN AND METHODS: We searched electronic databases (MEDLINE, Embase, PsycINFO, CINAHL) from inception through September 2016 to identify studies reporting data on palliative patients receiving RBC transfusion. Original studies that assessed RBC transfusion as an intervention and reported at least one clinical outcome were included...
December 1, 2017: Transfusion
https://www.readbyqxmd.com/read/29185142/initial-and-long-term-impact-of-a-multi-disciplinary-task-force-in-the-diagnosis-and-management-of-heparin-induced-thrombocytopenia
#4
Ming Y Lim, Joyce Foster, Angela Rourk, Charles S Greenberg
Many medical centers are faced with a major challenge in making an accurate diagnosis of heparin-induced thrombocytopenia (HIT) and ensuring appropriate changes in management strategy in line with guideline recommendations. We report the initial and long-term impact and challenges of institution-wide changes in the diagnosis and management of HIT in the inpatient setting at an academic medical center. We established a HIT Task Force, consisting of a multidisciplinary team of non-malignant hematologists, nursing, pharmacist, pathology, blood bank and clinical lab informatics...
November 28, 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29148749/glycosyl-cross-coupling-of-anomeric-nucleophiles-scope-mechanism-and-applications-in-the-synthesis-of-aryl-c-glycosides
#5
Feng Zhu, Jacob Rodriguez, Tianyi Yang, Ilia Kevlishvili, Eric Miller, Duk Yi, Sloane O'Neill, Michael Rourke, Peng Liu, Maciej A Walczak
Stereoselective manipulations at the C1 anomeric position of saccharides are one of the central goals of preparative carbohydrate chemistry. Historically, the majority of reactions forming a bond with anomeric carbon has focused on reactions of nucleophiles with saccharide donors equipped with a leaving group. Here, we describe a novel approach to stereoselective synthesis of C-aryl glycosides capitalizing on the highly stereospecific reaction of anomeric nucleophiles. First, methods for the preparation of anomeric stannanes have been developed and optimized to afford both anomers of common saccharides in high anomeric selectivities...
November 17, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29082788/prevalence-and-predictors-of-food-insecurity-among-people-living-with-hiv-affiliated-with-aids-service-organizations-in-ontario-canada
#6
Tsegaye Bekele, Jason Globerman, James Watson, Murray Jose-Boebridge, Richard Kennedy, Keith Hambly, Aranka Anema, Robert S Hogg, Sean B Rourke
Up to half of people living with HIV in resource-rich settings experience moderate to severe food insecurity. Food insecurity, in turn, has been linked to adverse health outcomes including poor antiretroviral adherence, poor HIV viral suppression, frailty, and mortality. We estimated the prevalence of food insecurity among 649 adults living with HIV and recruited from community-based AIDS service organizations in Ontario, Canada. Food security was assessed using the Canadian Household Food Security module. We used logistic regression modeling to identify demographic, socioeconomic, and psychosocial factors independently associated with food insecurity...
October 28, 2017: AIDS Care
https://www.readbyqxmd.com/read/29080061/perceived-cognitive-impairment-in-people-with-colorectal-cancer-who-do-and-do-not-receive-chemotherapy
#7
Haryana M Dhillon, Ian F Tannock, Gregory R Pond, Corrinne Renton, Sean B Rourke, Janette L Vardy
PURPOSE: Cognitive symptoms are common after cancer, but poorly associated with neuropsychological results. We previously reported colorectal cancer (CRC) patients had more cognitive impairment than controls. Here, we explore relationships between cognitive symptoms and neuropsychological domains. METHODS: Subjects with CRC (N = 362) and 72 healthy controls completed neuropsychological assessments and Functional Assessment of Cancer Therapy-Cognition (FACT-COG) at baseline (pre-chemotherapy) and 6, 12, and 24 months...
October 27, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29076932/evaluation-of-the-clinical-utility-of-a-real-time-pcr-assay-for-the-diagnosis-of-streptococcus-pneumoniae-bacteremia-in-children-a-retrospective-diagnostic-accuracy-study
#8
Jane Murphy, Sadhbh O' Rourke, Mary Corcoran, Nicola O' Sullivan, Robert Cunney, Richard Drew
BACKGROUND: The widespread uptake of pneumococcal vaccines has substantially reduced the incidence of invasive pneumococcal disease, such that pneumococcal bacteremia in children is now considered a relatively rare event. The objective of this study was to ascertain the clinical utility of a Streptococcus pneumoniae real-time PCR assay compared with standard blood culture for the diagnosis of pneumococcal bacteremia in children in the post-vaccine era. METHODS: A systematic retrospective review of laboratory and patient records from Children's University Hospital, Temple Street during a 6 year period was performed...
October 25, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29047413/itactic-implementing-treatment-algorithms-for-the-correction-of-trauma-induced-coagulopathy-study-protocol-for-a-multicentre-randomised-controlled-trial
#9
Kjersti Baksaas-Aasen, Lewis Gall, Simon Eaglestone, Claire Rourke, Nicole P Juffermans, J Carel Goslings, Paal Aksel Naess, Susan van Dieren, Sisse Rye Ostrowski, Jakob Stensballe, Marc Maegele, Simon J Stanworth, Christine Gaarder, Karim Brohi, Per I Johansson
BACKGROUND: Traumatic injury is the fourth leading cause of death globally. Half of all trauma deaths are due to bleeding and most of these will occur within 6 h of injury. Haemorrhagic shock following injury has been shown to induce a clotting dysfunction within minutes, and this early trauma-induced coagulopathy (TIC) may exacerbate bleeding and is associated with higher mortality and morbidity. In spite of improved resuscitation strategies over the last decade, current transfusion therapy still fails to correct TIC during ongoing haemorrhage and evidence for the optimal management of bleeding trauma patients is lacking...
October 18, 2017: Trials
https://www.readbyqxmd.com/read/28977721/signatures-of-polygenic-adaptation-associated-with-climate-across-the-range-of-a-threatened-fish-species-with-high-genetic-connectivity
#10
K A Harrisson, S J Amish, A Pavlova, S Narum, M Telonis-Scott, M L Rourke, J Lyon, Z Tonkin, D M Gilligan, B A Ingram, M Lintermans, H M Gan, C M Austin, G Luikart, P Sunnucks
Adaptive differences across species' ranges can have important implications for population persistence and conservation management decisions. Despite advances in genomic technologies, detecting adaptive variation in natural populations remains challenging. Key challenges in gene-environment association studies involve distinguishing the effects of drift from those of selection, and identifying subtle signatures of polygenic adaptation. We used paired-end restriction-site associated-DNA sequencing data (6605 biallelic single nucleotide polymorphisms; SNPs) to examine population structure and test for signatures of adaptation across the geographic range of an iconic Australian endemic freshwater fish species, the Murray cod Maccullochella peelii...
October 4, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28970934/reversible-c-c-bond-formation-at-a-triply-cyclometallated-platinum-iv-centre
#11
Paul A Shaw, Guy J Clarkson, Jonathan P Rourke
The oxidation of the tribenzylphosphine derivative of the doubly cylcometallated platinum(ii) complex of diphenylpyridine, 1, with PhICl2 led, as a first step, to the formation of a highly electrophilic metal centre which attacked the benzyl phosphine to give a triply cyclometallated species as the arenium ion. The highly acidic arenium ion protonated unreacted starting 1, a reaction that could be supressed by the addition of water, and gave the neutral species 2(t). Octahedral complex 2(t) was induced to reductively couple, with two five-membered rings coupling to give square planar complex 5 containing a nine-membered ring...
August 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28904041/engagement-of-people-with-lived-experience-in-primary-care-research-living-with-hiv-innovation-team-community-scholar-program
#12
Claire E Kendall, Esther Susanna Shoemaker, Lois Crowe, Ron Rosenes, Philip Lundrigan, Christine Bibeau, Shabnam Asghari, Marissa Becker, Sean B Rourke, Zack Marshall, Clare Liddy
No abstract text is available yet for this article.
September 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28899769/incidence-and-predictors-of-complications-due-to-urethral-stricture-in-patients-awaiting-urethroplasty
#13
Nathan Y Hoy, David W Chapman, Nicholas Dean, Keith F Rourke
PURPOSE: The purpose of this study is to examine the incidence and predictors of complications due to urethral stricture in patients awaiting urethroplasty. METHODS AND METHODS: A retrospective chart review of patients undergoing urethroplasty from 2009-2013 was performed. The primary outcome was complications, defined as any unplanned interaction with the health care system due to the urethral stricture during the period between decision for surgery and urethroplasty...
September 9, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28880109/how-adolescents-perceive-that-community-based-exercise-improves-their-well-being
#14
Kevin Rourke, Coralie J Wilson
OBJECTIVES: To determine if adolescents perceive community-based exercise as beneficial to their well-being and in what ways. METHODS: A New South Wales Police Citizens Youth Club ran a four-week fitness course. The classes involved: 1) sports including basketball and soccer, 2) non-contact boxing drills, and 3) games, both team games such as dodgeball and non-team games such as line tag. Parental consent to offer a survey at the completion of the course was requested during registration...
September 1, 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28855308/a-cross-sectional-population-based-study-of-breast-cancer-screening-among-women-with-hiv-in-ontario-canada
#15
Claire E Kendall, Sharon Walmsley, Cindy Lau, Nathaniel Jembere, Ann N Burchell, Mona Loutfy, Janet Raboud, Ron Rosenes, Sean B Rourke, Tony Antoniou
BACKGROUND: As women with HIV live longer, the need for age-appropriate breast cancer screening will increase. We compared rates of screening mammography among women with and without HIV. METHODS: We used administrative health databases to identify all women in Ontario, Canada, who were eligible for screening mammography (aged 50 to 74 yr and no history of breast cancer) as of Apr. 1, 2011. We used multivariable log-binomial regression to compare the 2-year period prevalence of screening mammography in 2011 to 2013 among women with and without HIV and to examine the correlates of screening among women with HIV...
August 30, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28835844/polar-bears-experience-skeletal-muscle-atrophy-in-response-to-food-deprivation-and-reduced-activity-in-winter-and-summer
#16
John P Whiteman, Henry J Harlow, George M Durner, Eric V Regehr, Bryan C Rourke, Manuel Robles, Steven C Amstrup, Merav Ben-David
When reducing activity and using stored energy during seasonal food shortages, animals risk degradation of skeletal muscles, although some species avoid or minimize the resulting atrophy while experiencing these conditions during hibernation. Polar bears may be food deprived and relatively inactive during winter (when pregnant females hibernate and hunting success declines for other demographic groups) as well as summer (when sea ice retreats from key foraging habitats). We investigated muscle atrophy in samples of biceps femoris collected from free-ranging polar bears in the Southern Beaufort Sea (SBS) throughout their annual cycle...
2017: Conservation Physiology
https://www.readbyqxmd.com/read/28835709/glycoprotein-2-is-a-specific-cell-surface-marker-of-human-pancreatic-progenitors
#17
Kathryn F Cogger, Ankit Sinha, Farida Sarangi, Emily C McGaugh, Diane Saunders, Craig Dorrell, Salvador Mejia-Guerrero, Yasaman Aghazadeh, Jillian L Rourke, Robert A Screaton, Markus Grompe, Philip R Streeter, Alvin C Powers, Marcela Brissova, Thomas Kislinger, M Cristina Nostro
PDX1(+)/NKX6-1(+) pancreatic progenitors (PPs) give rise to endocrine cells both in vitro and in vivo. This cell population can be successfully differentiated from human pluripotent stem cells (hPSCs) and hold the potential to generate an unlimited supply of β cells for diabetes treatment. However, the efficiency of PP generation in vitro is highly variable, negatively impacting reproducibility and validation of in vitro and in vivo studies, and consequently, translation to the clinic. Here, we report the use of a proteomics approach to phenotypically characterize hPSC-derived PPs and distinguish these cells from non-PP populations during differentiation...
August 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/28833500/primary-stability-of-a-cementless-acetabular-cup-in-a-cohort-of-patient-specific-finite-element-models
#18
Dermot O' Rourke, Rami Al-Dirini, Mark Taylor
The primary stability achieved during total hip arthroplasty determines the long-term success of cementless acetabular cups. Pre-clinical finite element testing of cups typically use a model of a single patient and assume the results can be extrapolated to the general population. This study explored the variability in predicted primary stability of a Pinnacle ® cementless acetabular cup in 103 patient-specific finite element models of the hemipelvis and examined the association between patient-related factors and the observed variability...
August 18, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28817947/mortality-and-health-service-use-following-acute-myocardial-infarction-among-persons-with-hiv-a-population-based-study
#19
Caroline Jeon, Cindy Lau, Claire E Kendall, Ann N Burchell, Ahmed M Bayoumi, Mona Loutfy, Sean B Rourke, Tony Antoniou
People with HIV have higher rates of acute myocardial infarction (AMI) than HIV-negative individuals. We compared mortality risk and health service use following AMI among people with and without HIV between January 1, 2002, and March 31, 2015. We conducted a population-based study using Ontario's administrative databases. Our primary outcomes were risk of inpatient death and death at 30 days following hospital discharge. In secondary analyses, we compared use of revascularization procedures within 90 days of AMI, as well as readmission or emergency department visits for heart disease and cardiology follow-up within 90 days of discharge...
September 14, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28802381/diagnosing-subtle-palatal-anomalies-validation-of-video-analysis-and-assessment-protocol-for-diagnosing-occult-submucous-cleft-palate
#20
Ryan Rourke, Seth M Weinberg, Mary L Marazita, Noel Jabbour
INTRODUCTION: Submucous cleft palate (SMCP) classically involves bifid uvula, zona pellucida, and notched hard palate. However, patients may present with more subtle anatomic abnormalities. The ability to detect these abnormalities is important for surgeons managing velopharyngeal dysfunction (VPD) or considering adenoidectomy. OBJECTIVES: Validate an assessment protocol for diagnosis of occult submucous cleft palate (OSMCP) and identify physical examination features present in patients with OSMCP in the relaxed and activated palate positions...
September 2017: International Journal of Pediatric Otorhinolaryngology
keyword
keyword
22188
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"